PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE
1EPX 10891264 CRYSTAL STRUCTURE ANALYSIS OF ALDOLASE FROM L. MEXICANA 2000-03-29 2000-07-13 Chudzik, D.M.,Michels, P.A.,de Walque, S.,Hol, W.G. Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases. J.Mol.Biol. 2000 300 697 707
1HZJ 11279032 HUMAN UDP-GALACTOSE 4-EPIMERASE: ACCOMMODATION OF UDP-N-ACETYLGLUCOSAMINE WITHIN THE ACTIVE SITE 2001-01-25 2001-05-09 Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site. J.Biol.Chem. 2001 276 15131 15136
1I3K 11279193 MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE 2001-02-15 2001-06-20 Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem. 2001 276 20617 20623
1I3L 11279193 MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE 2001-02-15 2001-06-20 Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem. 2001 276 20617 20623
1I3M 11279193 MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE 2001-02-15 2001-06-20 Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem. 2001 276 20617 20623
1I3N 11279193 MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE 2001-02-15 2001-06-20 Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem. 2001 276 20617 20623
1J8R 11440716 BINARY COMPLEX OF THE PAPG RECEPTOR-BINDING DOMAIN BOUND TO GBO4 RECEPTOR 2001-05-22 2001-06-22 Dodson, K.W.,Pinkner, J.S.,Rose, T.,Magnusson, G.,Hultgren, S.J.,Waksman, G. Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell(Cambridge,Mass.) 2001 105 733 743
1J8S 11440716 PAPG ADHESIN RECEPTOR BINDING DOMAIN-UNBOUND FORM 2001-05-22 2001-06-22 Dodson, K.W.,Pinkner, J.S.,Rose, T.,Magnusson, G.,Hultgren, S.J.,Waksman, G. Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell(Cambridge,Mass.) 2001 105 733 743
1G2R 11679764 Structure of Cytosolic Protein of Unknown Function Coded by Gene from NUSA/INFB Region, a YlxR Homologue 2000-10-20 2001-08-29 Osipiuk, J.,Gornicki, P.,Maj, L.,Dementieva, I.,Laskowski, R.,Joachimiak, A. Streptococcus pneumonia YlxR at 1.35 A shows a putative new fold. Acta Crystallogr.,Sect.D 2001 57 1747 1751
1JCT 11513584 Glucarate Dehydratase, N341L mutant Orthorhombic Form 2001-06-11 2001-09-05 Gulick, A.M.,Hubbard, B.K.,Gerlt, J.A.,Rayment, I. Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry 2001 40 10054 10062
1H72 11535056 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE 2001-07-02 2001-09-13 Krishna, S.S.,Zhou, T.,Daugherty, M.,Osterman, A.L.,Zhang, H. Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase Biochemistry 2001 40 10810 0
1ILV 11709173 Crystal Structure Analysis of the TM107 2001-05-08 2001-10-10 Zhang, R.G.,Skarina, T.,Katz, J.E.,Beasley, S.,Khachatryan, A.,Vyas, S.,Arrowsmith, C.H.,Clarke, S.,Edwards, A.,Joachimiak, A.,Savchenko, A. Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase. Structure 2001 9 1095 1106
1GKZ 11562470 Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) complxed with ADP 2001-08-22 2001-10-11 Machius, M.,Chuang, J.L.,Wynn, R.M.,Tomchick, D.R.,Chuang, D.T. Structure of Rat Bckd Kinase: Nucleotide-Induced Domain Communication in a Mitochondrial Protein Kinase. Proc.Natl.Acad.Sci.USA 2001 98 11218 0
1H74 11535056 CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE 2001-07-02 2001-11-28 Krishna, S.S.,Zhou, T.,Daugherty, M.,Osterman, A.L.,Zhang, H. Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase Biochemistry 2001 40 10810 0
1JPM 11747448 L-Ala-D/L-Glu Epimerase 2001-08-02 2001-12-21 Gulick, A.M.,Schmidt, D.M.,Gerlt, J.A.,Rayment, I. Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry 2001 40 15716 15724
1EBB 11827481 Bacillus stearothermophilus YhfR 2001-07-24 2002-02-11 Rigden, D.J.,Mello, L.V.,Setlow, P.,Jedrzejas, M.J. Structure and Mechanism of Action of a Cofactor-Dependent Phosphoglycerate Mutase Homolog from Bacillus Stearothermophilus with Broad Specificity Phosphatase Activity. J.Mol.Biol. 2002 315 1129 0
1JYL 11706035 Catalytic Mechanism of CTP:phosphocholine Cytidylyltransferase from Streptococcus pneumoniae (LicC) 2001-09-12 2002-02-22 Kwak, B.Y.,Zhang, Y.M.,Yun, M.,Heath, R.J.,Rock, C.O.,Jackowski, S.,Park, H.W. Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae. J.Biol.Chem. 2002 277 4343 4350
1KMP 11872840 Crystal structure of the Outer Membrane Transporter FecA Complexed with Ferric Citrate 2001-12-17 2002-03-06 Ferguson, A.D.,Chakraborty, R.,Smith, B.S.,Esser, L.,van der Helm, D.,Deisenhofer, J. Structural basis of gating by the outer membrane transporter FecA. Science 2002 295 1715 1719
1KV8 11900527 Crystal Structure of 3-Keto-L-Gulonate 6-Phosphate Decarboxylase 2002-01-25 2002-04-15 Wise, E.,Yew, W.S.,Babbitt, P.C.,Gerlt, J.A.,Rayment, I. Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry 2002 41 3861 3869
1KB4 11980721 Crystal Structure of VDR DNA-binding Domain Bound to a Canonical Direct Repeat with Three Base Pair Spacer (DR3) Response Element 2001-11-05 2002-05-03 Shaffer, P.L.,Gewirth, D.T. Structural basis of VDR-DNA interactions on direct repeat response elements. EMBO J. 2002 21 2242 2252
1KB6 11980721 Crystal Structure of VDR DNA-binding Domain Bound to Rat Osteocalcin (OC) Response Element 2001-11-05 2002-05-03 Shaffer, P.L.,Gewirth, D.T. Structural basis of VDR-DNA interactions on direct repeat response elements. EMBO J. 2002 21 2242 2252
1LB1 12006984 Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA 2002-04-01 2002-05-29 Snyder, J.T.,Worthylake, D.K.,Rossman, K.L.,Betts, L.,Pruitt, W.M.,Siderovski, D.P.,Der, C.J.,Sondek, J. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol. 2002 9 468 475
1KIU 12010488 FimH adhesin Q133N mutant-FimC chaperone complex with methyl-alpha-D-mannose 2001-12-03 2002-06-05 Hung, C.S.,Bouckaert, J.,Hung, D.,Pinkner, J.,Widberg, C.,DeFusco, A.,Auguste, C.G.,Strouse, R.,Langermann, S.,Waksman, G.,Hultgren, S.J. Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol. 2002 44 903 915
1KLF 12010488 FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE 2001-12-11 2002-06-05 Hung, C.S.,Bouckaert, J.,Hung, D.,Pinkner, J.,Widberg, C.,DeFusco, A.,Auguste, C.G.,Strouse, R.,Langermann, S.,Waksman, G.,Hultgren, S.J. Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol. 2002 44 903 915
1LC5 12119022 Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica in its apo state 2002-04-05 2002-06-28 Cheong, C.G.,Escalante-Semerena, J.C.,Rayment, I. Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes. Biochemistry 2002 41 9079 9089
1LC7 12119022 Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica complexed with a substrate 2002-04-05 2002-06-28 Cheong, C.G.,Escalante-Semerena, J.C.,Rayment, I. Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes. Biochemistry 2002 41 9079 9089
1LC8 12119022 Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica complexed with its reaction intermediate 2002-04-05 2002-06-28 Cheong, C.G.,Escalante-Semerena, J.C.,Rayment, I. Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes. Biochemistry 2002 41 9079 9089
1LEW 12086621 CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A 2002-04-10 2002-07-10 Chang, C.I.,Xu, B.E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J. Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. Mol.Cell 2002 9 1241 1249
1LOH 11991948 Streptococcus pneumoniae Hyaluronate Lyase in Complex with Hexasaccharide Hyaluronan Substrate 2002-05-06 2002-08-07 Jedrzejas, M.J.,Mello, L.V.,de Groot, B.L.,Li, S. Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate. J.Biol.Chem. 2002 277 28287 28297
1LXK 11991948 Streptococcus pneumoniae Hyaluronate Lyase in Complex with Tetrasaccharide Hyaluronan Substrate 2002-06-05 2002-08-07 Jedrzejas, M.J.,Mello, L.V.,de Groot, B.L.,Li, S. Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate. J.Biol.Chem. 2002 277 28287 28297
1KTN Structural Genomics, Protein EC1535 2002-01-16 2002-08-14 Zhang, R.,Joachimiak, A.,Edwards, A.,Skarina, T.,Evdokimova, E.,Savchenko, A. The 1.5A crystal structure of 2-deoxyribose-5-phosphate aldlase To be Published 0 0 0 0
1LNU 12084926 CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE 2002-05-03 2002-08-14 Liu, X.,Dai, S.,Crawford, F.,Fruge, R.,Marrack, P.,Kappler, J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc.Natl.Acad.Sci.USA 2002 99 8820 8825
1LON 12004071 Crystal Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with 6-phosphoryl-IMP, GDP and Hadacidin 2002-05-06 2002-08-28 Iancu, C.V.,Borza, T.,Fromm, H.J.,Honzatko, R.B. IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem. 2002 277 26779 26787
1JVZ 11755403 Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid 2001-09-01 2002-09-01 Kim, Y.,Hol, W.G. Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity CHEM.BIOL. 2001 8 1253 1264
1JW0 11755403 Structure of cephalosporin acylase in complex with glutarate 2001-09-01 2002-09-01 Kim, Y.,Hol, W.G. Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity CHEM.BIOL. 2001 8 1253 1264
1K4K 11796112 Crystal structure of E. coli Nicotinic acid mononucleotide adenylyltransferase 2001-10-08 2002-10-08 Zhang, H.,Zhou, T.,Kurnasov, O.,Cheek, S.,Grishin, N.V.,Osterman, A. Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD. Structure 2002 10 69 79
1IY9 Crystal structure of spermidine synthase 2002-07-26 2002-10-30 Tan, A.Y.,Smith, P.C.,Shen, J.,Xiao, R.,Acton, T.,Rost, B.,Montelione, G.,Hunt, J.F. Crystal structure of spermidine synthase To be Published 0 0 0 0
1MBY 12352953 Murine Sak Polo Domain 2002-08-04 2002-10-30 Leung, G.C.,Hudson, J.W.,Kozarova, A.,Davidson, A.,Dennis, J.W.,Sicheri, F. The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization. Nat.Struct.Biol. 2002 9 719 724
1MH0 12205081 Crystal structure of the anticoagulant slow form of thrombin 2002-08-18 2002-11-08 Pineda, A.O.,Savvides, S.,Waksman, G.,Di Cera, E. Crystal structure of the anticoagulant slow form of thrombin J.Biol.Chem. 2002 277 40177 40180
1MD2 12405825 CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013 2002-08-06 2002-12-11 Zhang, Z.,Merritt, E.A.,Ahn, M.,Roach, C.,Hou, Z.,Verlinde, C.L.,Hol, W.G.,Fan, E. Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin. J.Am.Chem.Soc. 2002 124 12991 12998
1KYT Crystal Structure of Thermoplasma acidophilum 0175 (APC014) 2002-02-05 2003-01-21 Kim, Y.,Joachimiak, A.,Edwards, A.,Xu, X.,Pennycooke, M.,Gu, J.,Cheung, F.,Christendat, D. Crystal Structure of Thermoplasma acidophilum 0175 (APC014) To be published 0 0 0 0
1NKK 12549906 COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR 2003-01-03 2003-02-11 Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry 2003 42 885 891
1LF9 12614608 CRYSTAL STRUCTURE OF BACTERIAL GLUCOAMYLASE COMPLEXED WITH ACARBOSE 2002-04-10 2003-02-25 Aleshin, A.E.,Feng, P.-H.,Honzatko, R.B.,Reilly, P.J. Crystal structure and evolution of prokaryotic glucoamylase J.Mol.Biol. 2003 327 61 73
1NB0 12623014 Crystal Structure of Human Riboflavin Kinase 2002-12-01 2003-03-11 Karthikeyan, S.,Zhou, Q.,Mseeh, F.,Grishin, N.V.,Osterman, A.L.,Zhang, H. Crystal Structure of Human Riboflavin Kinase Reveals a Beta Barrel Fold and a Novel Active Site Arch Structure 2003 11 265 273
1NOP 12618186 Crystal structure of human tyrosyl-DNA phosphodiesterase (Tdp1) in complex with vanadate, DNA and a human topoisomerase I-derived peptide 2003-01-16 2003-03-11 Davies, D.R.,Interthal, H.,Champoux, J.J.,Hol, W.G.J. Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide Chem.Biol. 2003 10 139 147
1O1Y 14997577 Crystal structure of a glutamine amidotransferase (tm1158) from thermotoga maritima at 1.70 A resolution 2003-02-12 2003-03-11 Schwarzenbacher, R.,Deacon, A.M.,Jaroszewski, L.,Brinen, L.S.,Canaves, J.M.,Dai, X.,Elsliger, M.A.,Floyd, R.,Godzik, A.,Grittini, C.,Grzechnik, S.K.,Klock, H.E.,Koesema, E.,Kovarik, J.S.,Kreusch, A.,Kuhn, P.,Lesley, S.A.,McMullan, D.,McPhillips, T.M.,Miller, M.D.,Morse, A.,Moy, K.,Nelson, M.S.,Ouyang, J.,Page, R.,Robb, A.,Quijano, K.,Spraggon, G.,Stevens, R.C.,van den Bedem, H.,Velasquez, J.,Vincent, J.,von Delft, F.,Wang, X.,West, B.,Wolf, G.,Hodgson, K.O.,Wooley, J.,Wilson, I.A. Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution. PROTEINS 2004 54 801 805
1N57 12621151 Crystal Structure of Chaperone Hsp31 2002-11-04 2003-03-18 Quigley, P.M.,Korotkov, K.,Baneyx, F.,Hol, W.G.J. The 1.6A Crystal Structure of the Class of Chaperone Represented by Escherichia coli Hsp31 Reveals a Putative Catalytic Triad Proc.Natl.Acad.Sci.USA 2003 100 3137 3142
1O1Z 15162496 Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) (TM1621) from Thermotoga maritima at 1.60 A resolution 2003-02-12 2003-04-01 Santelli, E.,Schwarzenbacher, R.,McMullan, D.,Biorac, T.,Brinen, L.S.,Canaves, J.M.,Cambell, J.,Dai, X.,Deacon, A.M.,Elsliger, M.A.,Eshagi, S.,Floyd, R.,Godzik, A.,Grittini, C.,Grzechnik, S.K.,Jaroszewski, L.,Karlak, C.,Klock, H.E.,Koesema, E.,Kovarik, J.S.,Kreusch, A.,Kuhn, P.,Lesley, S.A.,McPhillips, T.M.,Miller, M.D.,Morse, A.,Moy, K.,Ouyang, J.,Page, R.,Quijano, K.,Rezezadeh, F.,Robb, A.,Stevens, R.C.,van den Bedem, H.,Velasquez, J.,Vincent, J.,von Delft, F.,Wang, X.,West, B.,Wolf, G.,Xu, Q.,Hodgson, K.O.,Wooley, J.,Wilson, I.A. Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins 2004 56 167 170
1MKZ 15269205 Crystal structure of MoaB protein at 1.6 A resolution. 2002-08-29 2003-04-22 Sanishvili, R.,Beasley, S.,Skarina, T.,Glesne, D.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J.Biol.Chem. 2004 279 42139 42146
1NLY 12727865 Crystal structure of the traffic ATPase of the Helicobacter pylori type IV secretion system in complex with ATPgammaS 2003-01-08 2003-05-06 Savvides, S.N.,Yeo, H.J.,Beck, M.R.,Blaesing, F.,Lurz, R.,Lanka, E.,Buhrdorf, R.,Fischer, W.,Haas, R.,Waksman, G. VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion Embo J. 2003 22 1969 1980
1NLZ 12727865 Crystal structure of unliganded traffic ATPase of the type IV secretion system of helicobacter pylori 2003-01-08 2003-05-06 Savvides, S.N.,Yeo, H.J.,Beck, M.R.,Blaesing, F.,Lurz, R.,Lanka, E.,Buhrdorf, R.,Fischer, W.,Haas, R.,Waksman, G. VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion Embo J. 2003 22 1969 1980
1OPX 12727865 Crystal structure of the traffic ATPase (HP0525) of the Helicobacter pylori type IV secretion system bound by sulfate 2003-03-06 2003-05-06 Savvides, S.N.,Yeo, H.J.,Beck, M.R.,Blaesing, F.,Lurz, R.,Lanka, E.,Buhrdorf, R.,Fischer, W.,Haas, R.,Waksman, G. VirB11 ATPases are dynamic hexameric assemblies: New insights into bacterial type IV secretion Embo J. 2003 22 1969 1980
1N3E 12758074 Crystal structure of I-CreI bound to a palindromic DNA sequence I (palindrome of left side of wildtype DNA target sequence) 2002-10-28 2003-06-03 Chevalier, B.,Turmel, M.,Lemieux, C.,Monnat, R.J.,Stoddard, B.L. Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol. 2003 329 253 269
1NI4 12651851 HUMAN PYRUVATE DEHYDROGENASE 2002-12-20 2003-06-17 Ciszak, E.M.,Korotchkina, L.G.,Dominiak, P.M.,Sidhu, S.,Patel, M.S. Structural Basis for Flip-Flop Action of Thiamin Pyrophosphate-Dependent Enzymes Revealed by Human Pyruvate Dehydrogenase J.Biol.Chem. 2003 278 21240 21246
1NUW 12595528 Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate and Phosphate at pH 9.6 2003-02-01 2003-07-08 Choe, J.Y.,Iancu, C.V.,Fromm, H.J.,Honzatko, R.B. Metaphosphate in the active site of fructose-1,6-bisphosphatase J.BIOL.CHEM. 2003 278 16015 16020
1P4X 12837797 Crystal structure of SarS protein from Staphylococcus Aureus 2003-04-24 2003-07-08 Li, R.,Manna, A.C.,Dai, S.,Cheung, A.L.,Zhang, G. Crystal structure of the SarS protein from Staphylococcus aureus J.BACTERIOL. 2003 185 4219 4225
1M2Z 12151000 Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif 2002-06-26 2003-07-15 Bledsoe, R.B.,Montana, V.G.,Stanley, T.B.,Delves, C.J.,Apolito, C.J.,Mckee, D.D.,Consler, T.G.,Parks, D.J.,Stewart, E.L.,Willson, T.M.,Lambert, M.H.,Moore, J.T.,Pearce, K.H.,Xu, H.E. Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition Cell(Cambridge,Mass.) 2002 110 93 105
1NIG 15704011 2.0 A Structure of Protein of Unknown Function from Thermoplasma acidophilum 2002-12-23 2003-07-15 Sanishvili, R.,Pennycooke, M.,Gu, J.,Xu, X.,Joachimiak, A.,Edwards, A.M.,Christendat, D. Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: a new type of helical super-bundle. J.STRUCT.FUNCT.GENOM. 2004 5 231 240
1LXN 12866058 X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 2002-06-05 2003-07-29 Tao, X.,Khayat, R.,Christendat, D.,Savchenko, A.,Xu, X.,Goldsmith-Fischman, S.,Honig, B.,Edwards, A.,Arrowsmith, C.H.,Tong, L. Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C Proteins 2003 52 478 480
1NFH 12730210 Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding 2002-12-15 2003-08-05 Zhao, K.,Chai, X.,Marmorstein, R. Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA-binding J.Biol.Chem. 2003 278 26071 26077
1NFJ 12730210 Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding 2002-12-15 2003-08-05 Zhao, K.,Chai, X.,Marmorstein, R. Structure of a Sir2 substrate, alba, reveals a mechanism for deacetylation-induced enhancement of DNA-binding J.Biol.Chem. 2003 278 26071 26077
1NRL 12909012 Crystal Structure of the human PXR-LBD in complex with an SRC-1 coactivator peptide and SR12813 2003-01-25 2003-08-19 Watkins, R.E.,Davis-Searles, P.R.,Lambert, M.H.,Redinbo, M.R. Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor J.Mol.Biol. 2003 331 815 828
1O51 14997579 Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.50 A resolution 2003-08-01 2003-08-19 Schwarzenbacher, R.,von Delft, F.,Abdubek, P.,Ambing, E.,Biorac, T.,Brinen, L.S.,Canaves, J.M.,Cambell, J.,Chiu, H.J.,Dai, X.,Deacon, A.M.,DiDonato, M.,Elsliger, M.A.,Eshagi, S.,Floyd, R.,Godzik, A.,Grittini, C.,Grzechnik, S.K.,Hampton, E.,Jaroszewski, L.,Karlak, C.,Klock, H.E.,Koesema, E.,Kovarik, J.S.,Kreusch, A.,Kuhn, P.,Lesley, S.A.,Levin, I.,McMullan, D.,McPhillips, T.M.,Miller, M.D.,Morse, A.,Moy, K.,Ouyang, J.,Page, R.,Quijano, K.,Robb, A.,Spraggon, G.,Stevens, R.C.,van den Bedem, H.,Velasquez, J.,Vincent, J.,Wang, X.,West, B.,Wolf, G.,Xu, Q.,Hodgson, K.O.,Wooley, J.,Wilson, I.A. Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution Proteins 2004 54 810 813
1ORR 12642575 Crystal Structure of CDP-Tyvelose 2-Epimerase complexed with NAD and CDP 2003-03-14 2003-08-26 Koropatkin, N.M.,Liu, H.W.,Holden, H.M. High Resolution X-ray Structure of Tyvelose Epimerase from Salmonella typhi J.Biol.Chem. 2003 278 20874 20881
1OLX 12902323 Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase 2003-08-18 2003-08-28 Wynn, R.M.,Machius, M.,Chuang, J.L.,Li, J.,Tomchick, D.R.,Chuang, D.T. Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site. J.Biol.Chem. 2003 278 43402 0
1OOF 12881720 Complex of Drosophila odorant binding protein LUSH with ethanol 2003-03-03 2003-09-02 Kruse, S.W.,Zhao, R.,Smith, D.P.,Jones, D.N.M. Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol. 2003 10 694 700
1OOG 12881720 Complex of Drosophila odorant binding protein LUSH with propanol 2003-03-03 2003-09-02 Kruse, S.W.,Zhao, R.,Smith, D.P.,Jones, D.N.M. Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol. 2003 10 694 700
1OOH 12881720 Complex of Drosophila odorant binding protein LUSH with butanol 2003-03-03 2003-09-02 Kruse, S.W.,Zhao, R.,Smith, D.P.,Jones, D.N.M. Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol. 2003 10 694 700
1ORU Crystal Structure of APC1665, YUAD protein from Bacillus subtilis 2003-03-15 2003-09-23 Kim, Y.,Joachimiak, A.,Edwards, A.,Skarina, T.,Savchenko, A. Crystal Structure of APC1665, YUAD protein from Bacillus subtilis To be Published 0 0 0 0
1O5J Crystal structure of Periplasmic divalent cation tolerance protein (TM1056) from Thermotoga maritima at 1.95 A resolution 2003-09-19 2003-09-30 Joint Center for Structural Genomics (JCSG) Crystal structure of Periplasmic divalent cation tolerance protein (TM1056) from Thermotoga maritima at 1.95 A resolution To be published 0 0 0 0
1Q14 14502267 Structure and autoregulation of the yeast Hst2 homolog of Sir2 2003-07-18 2003-09-30 Zhao, K.,Chai, X.,Clements, A.,Marmorstein, R. Structure and autoregulation of the Yeast Hst2 homolog of Sir2 Nat.Struct.Biol. 2003 10 864 871
1P4C 14604988 High Resolution Structure of Oxidized Active Mutant of (S)-Mandelate Dehydrogenase 2003-04-22 2003-10-28 Sukumar, N.,Dewanti, A.R.,Mitra, B.,Mathews, F.S. High Resolution Structures of an Oxidized and Reduced Flavoprotein: THE WATER SWITCH IN A SOLUBLE FORM OF (S)-MANDELATE DEHYDROGENASE J.Biol.Chem. 2004 279 3749 3757
1P5B 14604988 High Resolution Structure of Reduced Active Mutant of (S)-Mandelate Dehydrogenase 2003-04-25 2003-10-28 Sukumar, N.,Dewanti, A.R.,Mitra, B.,Mathews, F.S. High resolution structures of an oxidized and reduced flavoprotein. The water switch in a soluble form of (S)-mandelate dehydrogenase J.Biol.Chem. 2004 279 3749 3757
1Q6R 14567674 Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-xylulose 5-phosphate 2003-08-13 2003-10-28 Wise, E.L.,Yew, W.S.,Gerlt, J.A.,Rayment, I. Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily Biochemistry 2003 42 12133 12142
1QY8 12970348 Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with Radicicol 2003-09-09 2003-11-11 Soldano, K.L.,Jivan, A.,Nicchitta, C.V.,Gewirth, D.T. Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation J.Biol.Chem. 2003 278 48330 48338
1QZ6 14578936 Structure of rabbit actin in complex with jaspisamide A 2003-09-15 2003-11-11 Klenchin, V.A.,Allingham, J.S.,King, R.,Tanaka, J.,Marriott, G.,Rayment, I. Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin Nat.Struct.Biol. 2003 10 1058 1063
1UJW 14528295 Structure of the complex between BtuB and Colicin E3 Receptor binding domain 2003-08-12 2003-11-25 Kurisu, G.,Zakharov, S.D.,Zhalnina, M.V.,Bano, S.,Eroukova, V.Y.,Rokitskaya, T.I.,Antonenko, Y.N.,Wiener, M.C.,Cramer, W.A. The structure of BtuB with bound colicin E3 R-domain implies a translocon NAT.STRUCT.BIOL. 2003 10 948 954
1MV5 Crystal structure of LmrA ATP-binding domain 2002-09-24 2003-12-02 Yuan, Y.,Chen, H.,Patel, D. Crystal structure of LmrA ATP-binding domain reveals the two-site alternating mechanism at molecular level To be Published 0 0 0 0
1NA6 14659759 Crystal structure of restriction endonuclease EcoRII mutant R88A 2002-11-26 2003-12-16 Zhou, X.E.,Wang, Y.,Reuter, M.,Mucke, M.,Kruger, D.H.,Meehan, E.J.,Chen, L. Crystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold. J.Mol.Biol. 2004 335 307 319
1R49 14594810 Human topoisomerase I (Topo70) double mutant K532R/Y723F 2003-10-03 2003-12-16 Interthal, H.,Quigley, P.M.,Hol, W.G.,Champoux, J.J. The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J.Biol.Chem. 2004 279 2984 2992
1R8I 14673074 Crystal structure of TraC 2003-10-24 2004-01-06 Yeo, H.-J.,Yuan, Q.,Beck, M.R.,Baron, C.,Waksman, G. Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101 Proc.Natl.Acad.Sci.USA 2003 100 15947 15952
1NO7 12574112 Structure of the Large Protease Resistant Upper Domain of VP5, the Major Capsid Protein of Herpes Simplex Virus-1 2003-01-15 2004-01-20 Bowman, B.R.,Baker, M.L.,Rixon, F.J.,Chiu, W.,Quiocho, F.A. Structure of the herpesvirus major capsid protein Embo J. 2003 22 757 765
1PZX Hypothetical protein APC36103 from Bacillus stearothermophilus: a lipid binding protein 2003-07-14 2004-01-20 Zhang, R.,Osipiuk, J.,Zhou, M.,Alkire, R.,Moy, S.,Collart, F.,Joachimiak, A. Lipid binding protein APC36103 from Bacillus Stearothermophilus To be Published 0 0 0 0
1R66 14570895 Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound 2003-10-14 2004-01-27 Allard, S.T.M.,Cleland, W.W.,Holden, H.M. High Resolution X-ray Structure of dTDP-Glucose 4,6-Dehydratase from Streptomyces venezuelae J.Biol.Chem. 2004 279 2211 2220
1OS6 14744127 Cytochrome c7 (PpcA) from Geobacter sulfurreducens 2003-03-18 2004-02-03 Pokkuluri, P.R.,Londer, Y.Y.,Duke, N.E.,Long, W.C.,Schiffer, M. Family of cytochrome c7-type proteins from Geobacter sulfurreducens: structure of one cytochrome c7 at 1.45 A resolution. Biochemistry 2004 43 849 859
1NXH X-RAY STRUCTURE: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT87 2003-02-10 2004-02-24 Khayat, R.,Savchenko, A.,Edwards, A.,Arowsmith, C.,Tong, L. X-RAY STRUCTURE OF MTH396 To be Published 0 0 0 0
1PWL 15146479 Crystal structure of human Aldose Reductase complexed with NADP and Minalrestat 2003-07-02 2004-02-24 El-Kabbani, O.,Darmanin, C.,Schneider, T.R.,Hazemann, I.,Ruiz, F.,Oka, M.,Joachimiak, A.,Schulze-Briese, C.,Tomizaki, T.,Mitschler, A.,Podjarny, A. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors PROTEINS 2004 55 805 813
1QWR Crystal Structure Analysis of the Mannose 6-Phosphate Isomerase from Bacillus subtilis 2003-09-03 2004-03-02 Kim, Y.,Lezondra, L.,Joachimiak, A. Crystal structure analysis of the mannose 6-phosphate isomerase from Bacillus subtilis To be Published 0 0 0 0
1Q1G 14982926 Crystal structure of Plasmodium falciparum PNP with 5'-methylthio-immucillin-H 2003-07-19 2004-03-16 Shi, W.,Ting, L.M.,Kicska, G.A.,Lewandowicz, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Kim, K.,Almo, S.C.,Schramm, V.L. Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION. J.Biol.Chem. 2004 279 18103 18106
1VJN Crystal structure of a putative zn-dependent hydrolase of the metallo-beta-lactamase superfamily (tm0207) from thermotoga maritima at 2.00 A resolution 2004-03-11 2004-03-16 Joint Center for Structural Genomics (JCSG) Crystal structure of Zn-dependent hydrolase of metallo-beta-lactamase superfamily (TM0207) from Thermotoga maritima at 2.00 A resolution To be published 0 0 0 0
1OSV 12718893 STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR 2003-03-20 2004-03-23 Mi, L.Z.,Devarakonda, S.,Harp, J.M.,Han, Q.,Pellicciari, R.,Willson, T.M.,Khorasanizadeh, S.,Rastinejad, F. Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR Mol.Cell 2003 11 1093 1100
1R61 The structure of predicted metal-dependent hydrolase from Bacillus stearothermophilus 2003-10-14 2004-03-30 Maderova, J.,Borek, D.,Tomchick, D.,Joachimiak, A.,Collart, F.,Otwinowski, Z. The structure of potential metal-dependent hydrolase with cyclase activity To be Published 0 0 0 0
1QX6 14725770 Crystal structure of Sortase B complexed with E-64 2003-09-04 2004-04-06 Zong, Y.,Mazmanian, S.K.,Schneewind, O.,Narayana, S.V. The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall Structure 2004 12 105 112
1S7M 15029242 Crystal Structure of HiaBD1 2004-01-29 2004-04-06 Yeo, H.J.,Cotter, S.E.,Laarmann, S.,Juehne, T.,St Geme, J.W.,Waksman, G. Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter. Embo J. 2004 23 1245 1256
1VJX Crystal structure of a putative ferritin-like diiron-carboxylate protein (tm1526) from thermotoga maritima at 2.30 A resolution 2004-04-01 2004-04-13 Joint Center for Structural Genomics (JCSG) Crystal structure of putative ferritin-like diiron-carboxylate protein (TM1526) from Thermotoga maritima at 2.30 A resolution To be published 0 0 0 0
1VJZ Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution 2004-04-08 2004-04-13 Joint Center for Structural Genomics (JCSG) Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution To be published 0 0 0 0
1VJZ Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution 2004-04-08 2004-04-13 Joint Center for Structural Genomics (JCSG) Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution To be published 0 0 0 0
1T2A Crystal structure of human GDP-D-mannose 4,6-dehydratase 2004-04-20 2004-05-10 Vedadi, M.,Walker, J.R.,Sharma, S.,Houston, S.,Wasney, G.,Loppnau, P.,Oppermann, U. Crystal Structure and Biophysical Characterization of Human GDP-D-mannose 4,6-dehydratase To be Published 0 0 0 0
1S5A Crystal Structure of Putative Isomerase from Bacillus subtilis 2004-01-20 2004-05-11 Kim, Y.,Lezondra, L.,Joachimiak, A. The Crystal Structure of APC1116 from Bacillus subtilis TO BE PUBLISHED 0 0 0 0
1R5T 15148397 The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast 2003-10-13 2004-05-25 Xie, K.,Sowden, M.P.,Dance, G.S.,Torelli, A.T.,Smith, H.C.,Wedekind, J.E. The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1. Proc.Natl.Acad.Sci.Usa 2004 101 8114 8119
1S6Y 2.3A crystal structure of phospho-beta-glucosidase 2004-01-28 2004-05-25 Tereshko, V.,Dementieva, I.,Kim, Y.,Collat, F.,Joachimiak, A.,Kossiakoff, A. 2.3A CRYSTAL STRUCTURE OF PHOSPHO-BETA-GLUCOSIDASE, licH Gene Product from BACILLUS STEAROTHERMOPHILUS To be Published 0 0 0 0
1SI3 15152257 Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex 2004-02-27 2004-05-25 Ma, J.B.,Ye, K.,Patel, D.J. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 2004 429 318 322
1SJA 15134446 X-ray structure of o-Succinylbenzoate Synthase complexed with N-acetylmethionine 2004-03-03 2004-06-01 Thoden, J.B.,Taylor-Ringia, E.A.,Garrett, J.B.,Gerlt, J.A.,Holden, H.M.,Rayment, I. Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis Biochemistry 2004 43 5716 5727
1SJB 15134446 X-ray structure of o-succinylbenzoate synthase complexed with o-succinylbenzoic acid 2004-03-03 2004-06-01 Thoden, J.B.,Taylor-Ringia, E.A.,Garrett, J.B.,Gerlt, J.A.,Holden, H.M.,Rayment, I. Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis Biochemistry 2004 43 5716 5727
1SVS 15128951 Structure of the K180P mutant of Gi alpha subunit bound to GppNHp. 2004-03-29 2004-06-01 Thomas, C.J.,Du, X.,Li, P.,Wang, Y.,Ross, E.M.,Sprang, S.R. Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit. Proc.Natl.Acad.Sci.USA 2004 101 7560 7565
1T47 15157070 Structure of fe2-HPPD bound to NTBC 2004-04-28 2004-06-15 Brownlee, J.,Johnson-Winters, K.,Harrison, D.H.T.,Moran, G.R. Structure of the Ferrous Form of (4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis in Complex with the Therapeutic Herbicide, NTBC Biochemistry 2004 43 6370 6377
1RT8 15274920 CRYSTAL STRUCTURE OF THE ACTIN-CROSSLINKING CORE OF SCHIZOSACCHAROMYCES POMBE FIMBRIN 2003-12-10 2004-06-22 Klein, M.G.,Shi, W.,Ramagopal, U.,Tseng, Y.,Wirtz, D.,Kovar, D.R.,Staiger, C.J.,Almo, S.C. Structure of the actin crosslinking core of fimbrin. Structure 2004 12 999 1013
1RT8 15274920 CRYSTAL STRUCTURE OF THE ACTIN-CROSSLINKING CORE OF SCHIZOSACCHAROMYCES POMBE FIMBRIN 2003-12-10 2004-06-22 Klein, M.G.,Shi, W.,Ramagopal, U.,Tseng, Y.,Wirtz, D.,Kovar, D.R.,Staiger, C.J.,Almo, S.C. Structure of the actin crosslinking core of fimbrin. Structure 2004 12 999 1013
1T6A Crystal Structure of Protein of Unknown Function from Bacillus stearothermophilus 2004-05-05 2004-07-06 Osipiuk, J.,Wu, R.,Moy, S.,Collart, F.,Joachimiak, A. X-ray crystal structure of hypothetical protein (RBSTP2229 gene product) from Bacillus stearothermophilus To be Published 0 0 0 0
1PS8 15272161 Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae 2003-06-20 2004-07-27 Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D 2004 60 1388 1395
1PU2 15272161 Crystal Structure of the K246R Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae 2003-06-23 2004-07-27 Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D 2004 60 1388 1395
1Q2X 15272161 Crystal Structure of the E243D Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae bound with substrate aspartate semialdehyde 2003-07-26 2004-07-27 Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D 2004 60 1388 1395
1U13 Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis 2004-07-14 2004-07-27 Podust, L.M.,Yermalitskaya, L.V.,Kim, Y.,Waterman, M.R. Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis To be published 0 0 0 0
1SR8 Structural Genomics, 1.9A crystal structure of cobalamin biosynthesis protein (cbiD) from Archaeoglobus fulgidus 2004-03-22 2004-08-03 Zhang, R.,Skarina, T.,Savchenko, A.,Edwards, A.,Joachimiak, A. 1.9A crystal structure of cobalamin biosynthesis protein (cbiD) from Archaeoglobus fulgidus To be Published 0 0 0 0
1SS4 Crystal Structure of the Glyoxalase Family Protein APC24694 from Bacillus cereus 2004-03-23 2004-08-03 Kim, Y.,Li, H.,Joachimiak, A. Crystal Structure of the Glyoxalase Family Protein APC24694 from Bacillus cereus To be Published 0 0 0 0
1SS4 Crystal Structure of the Glyoxalase Family Protein APC24694 from Bacillus cereus 2004-03-23 2004-08-03 Kim, Y.,Li, H.,Joachimiak, A. Crystal Structure of the Glyoxalase Family Protein APC24694 from Bacillus cereus To be Published 0 0 0 0
1T0B Structure of ThuA-like protein from Bacillus stearothermophilus 2004-04-08 2004-08-03 Borek, D.,Chen, Y.,Collart, F.,Joachimiak, A.,Otwinowski, Z. Analysis of chemical interactions in ThuA-like protein from Bacillus Stearothermophilus To be Published 0 0 0 0
1T1J Crystal structure of genomics APC5043 2004-04-16 2004-08-03 Dong, A.,Xu, X.,Liu, Y.,Zhang, R.,Savchenko, A.,Edwards, A. Crystal Structure of Conserved Hypothetical Protein PA1492 from Pseudomonas aeruginosa TO BE PUBLISHED 0 0 0 0
1TLJ 27932585 Crystal Structure of Conserved Protein of Unknown Function SSO0622 from Sulfolobus solfataricus 2004-06-09 2004-08-03 Currie, M.A.,Brown, G.,Wong, A.,Ohira, T.,Sugiyama, K.,Suzuki, T.,Yakunin, A.F.,Jia, Z. Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases. Rna 2017 23 346 354
1TP6 1.5 A Crystal Structure of a NTF-2 Like Protein of Unknown Function PA1314 from Pseudomonas aeruginosa 2004-06-15 2004-08-03 Zhang, R.,Xu, L.X.,Savchenko, A.,Edwards, A.,Joachimiak, A. 1.5A crystal structure of a hypothetical protein PA1314 from Pseudomonas aeruginosa To be Published 0 0 0 0
1PQP 15272161 Crystal Structure of the C136S Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with Aspartate Semialdehyde and Phosphate 2003-06-18 2004-08-10 Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D 2004 60 1388 1395
1PQU 15272161 Crystal Structure of the H277N Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with NADP, S-methyl cysteine sulfoxide and cacodylate 2003-06-19 2004-08-10 Blanco, J.,Moore, R.A.,Faehnle, C.R.,Coe, D.M.,Viola, R.E. The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D 2004 60 1388 1395
1W15 15311271 rat synaptotagmin 4 C2B domain in the presence of calcium 2004-06-16 2004-08-13 Dai, H.,Shin, O.-H.,Machius, M.,Tomchick, D.R.,Sudhof, T.C.,Rizo, J. Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4 Nat.Struct.Mol.Biol. 2004 11 844 0
1W16 15311271 rat synaptotagmin 4 C2B domain in the absence of calcium 2004-06-16 2004-08-13 Dai, H.,Shin, O.-H.,Machius, M.,Tomchick, D.R.,Sudhof, T.C.,Rizo, J. Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4 Nat.Struct.Mol.Biol. 2004 11 844 0
1TWU 2.0 A Crystal Structure of a YycE Protein of Unknown Function from Bacillus subtilis, Putative Glyoxalase/Fosfomycin Resistance Protein 2004-07-01 2004-08-17 Zhang, R.,Quartey, P.,Collart, F.,Joachimiak, A. 2.0 A crystal structure of a hypothetical protein yycE from Bacillus subtilis To be Published 0 0 0 0
1VL8 Crystal structure of Gluconate 5-dehydrogenase (TM0441) from Thermotoga maritima at 2.07 A resolution 2004-07-14 2004-08-17 Joint Center for Structural Genomics (JCSG) Crystal structure of Gluconate 5-dehydrogenase (TM0441) from Thermotoga maritima at 2.07 A resolution To be published 0 0 0 0
1VKZ Crystal structure of Phosphoribosylamine--glycine ligase (TM1250) from Thermotoga maritima at 2.30 A resolution 2004-06-29 2004-08-24 Joint Center for Structural Genomics (JCSG) Crystal structure of Phosphoribosylamine--glycine ligase (TM1250) from Thermotoga maritima at 2.30 A resolution To be published 0 0 0 0
1SWX 15329726 Crystal structure of a human glycolipid transfer protein in apo-form 2004-03-30 2004-08-31 Malinina, L.,Malakhova, M.L.,Teplov, A.,Brown, R.E.,Patel, D.J. Structural basis for glycosphingolipid transfer specificity. Nature 2004 430 1048 1053
1T5I 15296731 Crystal structure of the C-terminal domain of UAP56 2004-05-04 2004-08-31 Zhao, R.,Shen, J.,Green, M.R.,Macmorris, M.,Blumenthal, T. Crystal structure of UAP56, a ""DEXD/H-box"" protein involved in pre-mRNA splicing and mRNA export Structure 2004 12 1373 1381
1T6N 15296731 Crystal structure of the N-terminal domain of human UAP56 2004-05-06 2004-08-31 Zhao, R.,Shen, J.,Green, M.R.,MacMorris, M.,Blumenthal, T. Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export Structure 2004 12 1373 1381
1T2W 15117963 Crystal Structure of Sortase A in Complex with a LPETG peptide 2004-04-23 2004-09-07 Zong, Y.,Bice, T.W.,Ton-That, H.,Schneewind, O.,Narayana, S.V. Crystal structure of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem. 2004 279 31383 31389
1TJN Crystal structure of hypothetical protein af0721 from Archaeoglobus fulgidus 2004-06-06 2004-09-07 Yin, J.,Xu, X.L.,Cuff, M.,Walker, J.R.,Edwards, A.,Savchenko, A.,James, M.N.G. Crystal structure of af0721: a hypothetical protein bearing sequence similarity with class II chelatases in cobalamin synthesis To be Published 0 0 0 0
1U2X 19553681 Crystal Structure of a Hypothetical ADP-dependent Phosphofructokinase from Pyrococcus horikoshii OT3 2004-07-20 2004-09-14 Currie, M.A.,Merino, F.,Skarina, T.,Wong, A.H.,Singer, A.,Brown, G.,Savchenko, A.,Caniuguir, A.,Guixe, V.,Yakunin, A.F.,Jia, Z. ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645. J.Biol.Chem. 2009 284 22664 22671
1U14 The crystal structure of hypothetical UPF0244 protein yjjX at resolution 1.68 Angstrom 2004-07-14 2004-09-21 Qiu, Y.,Kim, Y.,Cuff, M.,Collart, F.,Joachimiak, A.,Kossiakoff, A. The crystal structure of hypothetical UPF0244 protein yjjX at resolution 1.68 Angstrom To be Published 0 0 0 0
1U69 16493657 Crystal Structure of PA2721 Protein of Unknown Function from Pseudomonas aeruginosa PAO1 2004-07-29 2004-09-21 Nocek, B.,Cuff, M.,Evdokimova, E.,Edwards, A.,Joachimiak, A.,Savchenko, A. 1.6 A crystal structure of a PA2721 protein from pseudomonas aeruginosa--a potential drug-resistance protein. Proteins 2006 63 1102 1105
1U9D Structure of Protein of Unknown Function from Vibrio cholerae O1 biovar eltor str. N16961 2004-08-09 2004-09-21 Binkowski, T.A.,Wu, R.,Moy, S.F.,Joachimiak, A. Hypothetical Protein from Vibrio cholerae O1 biovar eltor str. N16961 TO BE PUBLISHED 0 0 0 0
1VJV Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution 2004-03-29 2004-09-21 Joint Center for Structural Genomics (JCSG) Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution To be published 0 0 0 0
1XFI 16511115 X-ray structure of gene product from Arabidopsis thaliana At2g17340 2004-09-14 2004-09-28 Bitto, E.,Bingman, C.A.,Allard, S.T.,Wesenberg, G.E.,Phillips, G.N. The structure at 1.7 A resolution of the protein product of the At2g17340 gene from Arabidopsis thaliana. Acta Crystallogr.,Sect.F 2005 61 630 635
1XJ5 X-RAY STRUCTURE OF SPERMIDINE SYNTHASE FROM ARABIDOPSIS THALIANA GENE AT1G23820 2004-09-22 2004-10-05 Center for Eukaryotic Structural Genomics X-RAY STRUCTURE OF SPERMIDINE SYNTHASE FROM ARABIDOPSIS THALIANA GENE AT1G23820 To be published 0 0 0 0
1U5Q 15458637 Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K 2004-07-28 2004-10-12 Zhou, T.,Raman, M.,Gao, Y.,Earnest, S.,Chen, Z.,Machius, M.,Cobb, M.H.,Goldsmith, E.J. Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K. STRUCTURE 2004 12 1891 1900
1U5R 15458637 Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K 2004-07-28 2004-10-12 Zhou, T.,Raman, M.,Gao, Y.,Earnest, S.,Chen, Z.,Machius, M.,Cobb, M.H.,Goldsmith, E.J. Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K. Structure 2004 12 1891 1900
1VMK Crystal structure of Purine nucleoside phosphorylase (TM1596) from Thermotoga maritima at 2.01 A resolution 2004-09-30 2004-10-12 Joint Center for Structural Genomics (JCSG) Crystal structure of Purine nucleoside phosphorylase (TM1596) from Thermotoga maritima at 2.01 A resolution To be published 0 0 0 0
1XMB 18543330 X-ray structure of IAA-aminoacid hydrolase from Arabidopsis thaliana gene AT5G56660 2004-10-01 2004-10-12 Bitto, E.,Bingman, C.A.,Bittova, L.,Houston, N.L.,Boston, R.S.,Fox, B.G.,Phillips Jr., G.N. X-ray structure of ILL2, an auxin-conjugate amidohydrolase from Arabidopsis thaliana. Proteins 2009 74 61 71
1XMB 18543330 X-ray structure of IAA-aminoacid hydrolase from Arabidopsis thaliana gene AT5G56660 2004-10-01 2004-10-12 Bitto, E.,Bingman, C.A.,Bittova, L.,Houston, N.L.,Boston, R.S.,Fox, B.G.,Phillips Jr., G.N. X-ray structure of ILL2, an auxin-conjugate amidohydrolase from Arabidopsis thaliana. Proteins 2009 74 61 71
1XQ1 X-RAY STRUCTURE OF PUTATIVE TROPINONE REDUCATSE FROM ARABIDOPSIS THALIANA GENE AT1G07440 2004-10-11 2004-10-19 Center for Eukaryotic Structural Genomics X-RAY STRUCTURE OF PUTATIVE TROPINONE REDUCATSE FROM ARABIDOPSIS THALIANA GENE AT1G07440 To be published 0 0 0 0
1U5K 15458636 Recombinational repair protein RecO 2004-07-27 2004-10-26 Makharashvili, N.,Koroleva, O.,Bera, S.,Grandgenett, D.P.,Korolev, S. A Novel Structure of DNA Repair Protein RecO from Deinococcus radiodurans STRUCTURE 2004 12 1881 1889
1U5K 15458636 Recombinational repair protein RecO 2004-07-27 2004-10-26 Makharashvili, N.,Koroleva, O.,Bera, S.,Grandgenett, D.P.,Korolev, S. A Novel Structure of DNA Repair Protein RecO from Deinococcus radiodurans STRUCTURE 2004 12 1881 1889
1VPD 19184529 X-Ray Crystal Structure of Tartronate Semialdehyde Reductase [Salmonella Typhimurium LT2] 2004-10-22 2004-10-26 Osipiuk, J.,Zhou, M.,Moy, S.,Collart, F.,Joachimiak, A. X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium. J Struct Funct Genomics 2009 10 249 253
1XRI 18433060 X-ray structure of a putative phosphoprotein phosphatase from Arabidopsis thaliana gene AT1G05000 2004-10-14 2004-10-26 Aceti, D.J.,Bitto, E.,Yakunin, A.F.,Proudfoot, M.,Bingman, C.A.,Frederick, R.O.,Sreenath, H.K.,Vojtik, F.C.,Wrobel, R.L.,Fox, B.G.,Markley, J.L.,Phillips Jr., G.N. Structural and functional characterization of a novel phosphatase from the Arabidopsis thaliana gene locus At1g05000. Proteins 2008 73 241 253
1RY0 14979715 Structure of prostaglandin F synthase with prostaglandin D2 2003-12-19 2004-11-02 Komoto, J.,Yamada, T.,Watanabe, K.,Takusagawa, F. Crystal structure of human prostaglandin F synthase (AKR1C3). Biochemistry 2004 43 2188 2198
1RY8 14979715 Prostaglandin F synthase complexed with NADPH and rutin 2003-12-19 2004-11-02 Komoto, J.,Yamada, T.,Watanabe, K.,Takusagawa, F. Crystal structure of human prostaglandin F synthase (AKR1C3). Biochemistry 2004 43 2188 2198
1VPA Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution 2004-10-14 2004-11-02 Joint Center for Structural Genomics (JCSG) Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution To be published 0 0 0 0
1XPM 15498869 Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine 2004-10-08 2004-11-02 Theisen, M.J.,Misra, I.,Saadat, D.,Campobasso, N.,Miziorko, H.M.,Harrison, D.H.T. 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in ""real-time"" Proc.Natl.Acad.Sci.USA 2004 47 16442 16447
1XU1 15542592 The crystal structure of APRIL bound to TACI 2004-10-25 2004-11-09 Hymowitz, S.G.,Patel, D.R.,Wallweber, H.J.A.,Runyon, S.,Yan, M.,Yin, J.,Shriver, S.K.,Gordon, N.C.,Pan, B.,Skelton, N.J.,Kelley, R.F.,Starovasnik, M.A. Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem. 2005 280 7218 7227
1XU2 15542592 The crystal structure of APRIL bound to BCMA 2004-10-25 2004-11-09 Hymowitz, S.G.,Patel, D.R.,Wallweber, H.J.A.,Runyon, S.,Yan, M.,Yin, J.,Shriver, S.K.,Gordon, N.C.,Pan, B.,Skelton, N.J.,Kelley, R.F.,Starovasnik, M.A. Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem. 2005 280 7218 7227
1XQ5 Met-Perch Hemoglobin at 1.9A 2004-10-11 2004-11-16 Center for Eukaryotic Structural Genomics (CESG) Met-Perch Hemoglobin at 1.9A To be Published 0 0 0 0
1XTE 15126499 crystal structure of CISK-PX domain 2004-10-21 2004-11-16 Xing, Y.,Liu, D.,Zhang, R.,Joachimiak, A.,Songyang, Z.,Xu, W. Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX) J.Biol.Chem. 2004 279 30662 30669
1VPQ CRYSTAL STRUCTURE OF a DUF72 family protein (TM1631) FROM THERMOTOGA MARITIMA MSB8 AT 2.20 A RESOLUTION 2004-11-16 2004-11-23 Joint Center for Structural Genomics (JCSG) Crystal structure of hypothetical protein (TM1631) from Thermotoga maritima at 2.20 A resolution To be published 0 0 0 0
1XI9 Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001 2004-09-21 2004-11-23 Zhou, W.,Tempel, W.,Shah, A.,Chen, L.,Liu, Z.-J.,Lee, D.,Lin, D.,Chang, S.-H.,Brereton, P.S.,Izumi, M.,Jenney Jr., F.E.,Lee, H.-S.,Poole II, F.L.,Shah, C.,Sugar, F.J.,Arendall III, W.B.,Richardson, J.S.,Richardson, D.C.,Rose, J.P.,Adams, M.W.W.,Wang, B.-C.,Southeast Collaboratory for Structural Genomics Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001 To be published 0 0 0 0
1XPP Crystal Structure of TA1416,DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum 2004-10-09 2004-11-23 Kim, Y.,Joachimiak, A.,Evdokimova, E.,Savchenko, A.,Edwards, A. Crystal structure of TA1416, DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum To be Published 0 0 0 0
1XQA Structure of a possible Glyoxalase from Bacillus cereus 2004-10-11 2004-11-23 Cuff, M.E.,Li, H.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Structure of a possible Glyoxalase from Bacillus cereus To be Published 0 0 0 0
1XR4 X-ray crystal structure of putative citrate lyase alpha chain/citrate-ACP transferase [Salmonella typhimurium] 2004-10-13 2004-11-30 Osipiuk, J.,Quartey, P.,Moy, S.,Collart, F.,Joachimiak, A. X-ray crystal structure of putative citrate lyase alpha chain/citrate-ACP transferase from Salmonella typhimurium. To be Published 0 0 0 0
1Y0Z 16511070 X-ray structure of gene product from Arabidopsis thaliana At3g21360 2004-11-16 2004-11-30 Bitto, E.,Bingman, C.A.,Allard, S.T.,Wesenberg, G.E.,Aceti, D.J.,Wrobel, R.L.,Frederick, R.O.,Sreenath, H.,Vojtik, F.C.,Jeon, W.B.,Newman, C.S.,Primm, J.,Sussman, M.R.,Fox, B.G.,Markley, J.L.,Phillips, G.N. The structure at 2.4 A resolution of the protein from gene locus At3g21360, a putative Fe(II)/2-oxoglutarate-dependent enzyme from Arabidopsis thaliana. Acta Crystallogr.,Sect.F 2005 61 469 472
1RD6 16428843 Crystal Structure of S. Marcescens Chitinase A Mutant W167A 2003-11-05 2004-12-07 Aronson, N.N.,Halloran, B.A.,Alexeyev, M.F.,Zhou, X.E.,Wang, Y.,Meehan, E.J.,Chen, L. Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation. Biosci.Biotechnol.Biochem. 2006 70 243 251
1VPV Crystal structure of a degv lipid binding protein (tm1468) from thermotoga maritima at 2.45 A resolution 2004-11-18 2004-12-07 Joint Center for Structural Genomics (JCSG) Crystal structure of UPF0230 protein TM1468 (TM1468) from Thermotoga maritima at 2.45 A resolution To be published 0 0 0 0
1RRK 15068800 Crystal Structure Analysis of the Bb segment of Factor B 2003-12-08 2004-12-14 Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell 2004 14 17 28
1TL7 15591060 Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-triphosphate and Mn 2004-06-09 2004-12-14 Mou, T.C.,Gille, A.,Fancy, D.A.,Seifert, R.,Sprang, S.R. Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate. J.Biol.Chem. 2005 280 7253 7261
1U0H 15591060 STRUCTURAL BASIS FOR THE INHIBITION OF MAMMALIAN ADENYLYL CYCLASE BY MANT-GTP 2004-07-13 2004-12-14 Mou, T.C.,Gille, A.,Fancy, D.A.,Seifert, R.,Sprang, S.R. Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate. J.Biol.Chem. 2005 280 7253 7261
1VKC Putative acetyl transferase from Pyrococcus furiosus 2004-05-11 2004-12-14 Habel, J.E.,Liu, Z.-J.,Tempel, W.,Rose, J.P.,BRERETON, P.S.,IZUMI, M.,JENNEY JR, F.E.,POOLE II, F.L.,SHAH, C.,SUGAR, F.J.,ADAMS, M.W.W.,RICHARDSON, D.C.,RICHARDSON, J.S.,Wang, B.-C.,Southeast Collaboratory for Structural Genomics Putative acetyl transferase from Pyrococcus furiosus To be published 0 0 0 0
1XVI Crystal Structure of YedP, phosphatase-like domain protein from Escherichia coli K12 2004-10-28 2004-12-14 Kim, Y.,Joachimiak, A.,Cymborowski, M.,Skarina, T.,Savchenko, A.,Edwards, A. Crystal Structure of YedP, phosphatase-like domain protein from Escherichia coli K12 To be Published 0 0 0 0
1XVI Crystal Structure of YedP, phosphatase-like domain protein from Escherichia coli K12 2004-10-28 2004-12-14 Kim, Y.,Joachimiak, A.,Cymborowski, M.,Skarina, T.,Savchenko, A.,Edwards, A. Crystal Structure of YedP, phosphatase-like domain protein from Escherichia coli K12 To be Published 0 0 0 0
1Y0N Structure of Protein of Unknown Function PA3463 from Pseudomonas aeruginosa PAO1 2004-11-15 2004-12-21 Binkowski, T.A.,Edwards, A.,Savchenko, A.,Skarina, T.,Gorodichtchenskaia, E.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Hypothetical protein PA3463 from Pseudomonas aeruginosa strain PAO1 To be Published 0 0 0 0
1Y88 Crystal Structure of Protein of Unknown Function AF1548 2004-12-10 2004-12-21 Lunin, V.V.,Evdokimova, E.,Kudritskaya, M.,Cuff, M.E.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of hypothetical protein AF1548 from Archaeoglobus fulgidus To be Published 0 0 0 0
1RXD 18058037 Crystal structure of human protein tyrosine phosphatase 4A1 2003-12-18 2004-12-28 Almo, S.C.,Bonanno, J.B.,Sauder, J.M.,Emtage, S.,Dilorenzo, T.P.,Malashkevich, V.,Wasserman, S.R.,Swaminathan, S.,Eswaramoorthy, S.,Agarwal, R.,Kumaran, D.,Madegowda, M.,Ragumani, S.,Patskovsky, Y.,Alvarado, J.,Ramagopal, U.A.,Faber-Barata, J.,Chance, M.R.,Sali, A.,Fiser, A.,Zhang, Z.Y.,Lawrence, D.S.,Burley, S.K. Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM. 2007 8 121 140
1XF9 15619636 Structure of NBD1 from murine CFTR- F508S mutant 2004-09-14 2004-12-28 Thibodeau, P.H.,Brautigam, C.A.,Machius, M.,Thomas, P.J. Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol. 2005 12 10 16
1XFA 15619636 Structure of NBD1 from murine CFTR- F508R mutant 2004-09-14 2004-12-28 Thibodeau, P.H.,Brautigam, C.A.,Machius, M.,Thomas, P.J. Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol. 2005 12 10 16
1Y0E Crystal structure of putative ManNAc-6-P epimerase from Staphylococcus aureus (strain N315) 2004-11-15 2004-12-28 Chang, C.,Moy, S.,Li, H.,Joachimiak, A. Crystal structure of putative ManNAc-6-P epimerase from Staphylococcus aureus (strain N315) To be Published 0 0 0 0
1Y0U Crystal Structure of the putative arsenical resistance operon repressor from Archaeoglobus fulgidus 2004-11-16 2004-12-28 Kim, Y.,Joachimiak, A.,Skarina, T.,Savchenko, A.,Edwards, A. Crystal Structure of the putative arsenical resistance operon repressor from Archaeoglobus fulgidus To be Published 0 0 0 0
1YCN X-RAY STRUCTURE OF ANNEXIN FROM ARABIDOPSIS THALIANA GENE AT1G35720 2004-12-22 2005-01-04 Center for Eukaryotic Structural Genomics (CESG) X-RAY STRUCTURE OF ANNEXIN FROM ARABIDOPSIS THALIANA GENE AT1G35720 To be published 0 0 0 0
1YDH 17048257 X-ray structure of a lysine decarboxylase-like protein from arabidopsis thaliana gene at5g11950 2004-12-23 2005-01-11 Jeon, W.B.,Allard, S.T.M.,Bingman, C.A.,Bitto, E.,Han, B.W.,Wesenberg, G.E.,Phillips Jr., G.N. X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210. Proteins 2006 65 1051 1054
1Y5E Crystal structure of Molybdenum cofactor biosynthesis protein B 2004-12-02 2005-01-18 Chang, C.,Zhou, M.,Abdullah, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of Molybdenum cofactor biosynthesis protein B TO BE PUBLISHED 0 0 0 0
1Y71 X-ray crystal structure of kinase-associated protein B from Bacillus cereus 2004-12-07 2005-01-18 Osipiuk, J.,Zhou, M.,Moy, S.,Collart, F.,Joachimiak, A. X-ray crystal structure of kinase-associated protein B from Bacillus cereus To be Published 0 0 0 0
1SG0 15350128 Crystal structure analysis of QR2 in complex with resveratrol 2004-02-22 2005-01-25 Buryanovskyy, L.,Fu, Y.,Boyd, M.,Ma, Y.,Hsieh, T.C.,Wu, J.M.,Zhang, Z. Crystal structure of quinone reductase 2 in complex with resveratrol Biochemistry 2004 43 11417 11426
1T00 16510983 The structure of thioredoxin from S. coelicolor 2004-04-07 2005-01-25 Stefankova, P.,Maderova, J.,Barak, I.,Kollarova, M.,Otwinowski, Z. Expression, purification and X-ray crystallographic analysis of thioredoxin from Streptomyces coelicolor. Acta Crystallogr.,Sect.F 2005 61 164 168
1XZZ 15664189 Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor 2004-11-13 2005-01-25 Bosanac, I.,Yamazaki, H.,Matsu-Ura, T.,Michikawa, T.,Mikoshiba, K.,Ikura, M. Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol.Cell 2005 17 193 203
1XZZ 15664189 Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor 2004-11-13 2005-01-25 Bosanac, I.,Yamazaki, H.,Matsu-Ura, T.,Michikawa, T.,Mikoshiba, K.,Ikura, M. Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol.Cell 2005 17 193 203
1Y8A Structure of gene product AF1437 from Archaeoglobus fulgidus 2004-12-10 2005-01-25 Cuff, M.E.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Structure of gene product AF1437 from Archaeoglobus fulgidus To be published 0 0 0 0
1Y8A Structure of gene product AF1437 from Archaeoglobus fulgidus 2004-12-10 2005-01-25 Cuff, M.E.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Structure of gene product AF1437 from Archaeoglobus fulgidus To be published 0 0 0 0
1Y9B Structure of Conserved Putative Transcriptional Factor from Vibrio cholerae O1 biovar eltor str. N16961 2004-12-15 2005-01-25 Binkowski, T.A.,Hatzos, C.,Quartey, P.,Moy, S.,Joachimiak, A. Conserverd hypothetical protein from Vibrio cholerae O1 biovar eltor str. N16961 To be Published 0 0 0 0
1Y9K IAA acetyltransferase from Bacillus cereus ATCC 14579 2004-12-15 2005-02-01 Nocek, B.P.,Osipiuk, J.,Li, H.,Collart, F.,Joachimiak, A. A crystal structure of IAA acetyltransferase from Bacillus cereus To be Published 0 0 0 0
1YOY Predicted coding region AF1432 from Archaeoglobus Fulgidus 2005-01-28 2005-02-08 Lunin, V.V.,Evdokimova, E.,Kudritskaya, M.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of predicted coding region AF1432 from Archaeoglobus Fulgidus To be Published 0 0 0 0
1UWF 15659162 1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli 2004-02-05 2005-02-16 Bouckaert, J.,Berglund, J.,Schembri, M.,De Genst, E.,Cools, L.,Wuhrer, M.,Hung, C.,Pinkner, J.,Slattegard, R.,Zavialov, A.,Choudhury, D.,Langermann, S.,Hultgren, S.J.,Wyns, L.,Klemm, P.,Oscarson, S.,Knight, S.D.,De Greve, H. Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin. Mol.Microbiol. 2005 55 441 0
1SC6 15035616 Crystal Structure of W139G D-3-Phosphoglycerate dehydrogenase complexed with NAD+ 2004-02-11 2005-02-22 Bell, J.K.,Grant, G.A.,Banaszak, L.J. Multiconformational states in phosphoglycerate dehydrogenase Biochemistry 2004 43 3450 3458
1YHF Crystal Structure of Conserved SPY1581 Protein of Unknown Function from Streptococcus pyogenes 2005-01-07 2005-02-22 Osipiuk, J.,Lezondra, L.,Moy, S.,Collart, F.,Joachimiak, A. X-ray crystal structure of conserved hypothetical SPy1581 protein from Streptococcus pyogenes. To be Published 0 0 0 0
1YVI X-RAY STRUCTURE OF PUTATIVE HISTIDINE-CONTAINING PHOSPHOTRANSFER PROTEIN FROM RICE, AK104879 2005-02-15 2005-02-22 Center for Eukaryotic Structural Genomics (CESG) X-RAY STRUCTURE OF PUTATIVE HISTIDINE-CONTAINING PHOSPHOTRANSFER PROTEIN FROM RICE, AK104879 To be published 0 0 0 0
1PWO 15720395 Crystal Structure of Phospholipase A2 (MIPLA2) from Micropechis Ikaheka 2003-07-02 2005-03-01 Lok, S.M.,Gao, R.,Rouault, M.,Lambeau, G.,Gopalakrishnakone, P.,Swaminathan, K. Structure and function comparison of Micropechis ikaheka snake venom phospholipase A2 isoenzymes. Febs J. 2005 272 1211 1220
1XG4 15723538 Crystal Structure of the C123S 2-Methylisocitrate Lyase Mutant from Escherichia coli in complex with the inhibitor isocitrate 2004-09-16 2005-03-01 Liu, S.,Lu, Z.,Han, Y.,Melamud, E.,Dunaway-Mariano, D.,Herzberg, O. Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution Biochemistry 2005 44 2949 2962
1YLE The structure of arginine/ornithine succinyltransferase subunit AI from Pseudomonas aeruginosa. 2005-01-19 2005-03-01 Cuff, M.E.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A.,MCSG The structure of arginine/ornithine succinyltransferase subunit AI from Pseudomonas aeruginosa. To be Published 0 0 0 0
1SHM 15826665 Convergent solutions to VHH domain stabilization from natural and in vitro evolution 2004-02-26 2005-03-08 Bond, C.J.,Wiesmann, C.,Marsters, J.C.,Sidhu, S.S. A structure-based database of antibody variable domain diversity. J.Mol.Biol. 2005 348 699 709
1YJ0 Crystal Structures of Chicken Annexin V in Complex with Zn2+ 2005-01-11 2005-03-08 Ortlund, E.A.,Chai, G.,Genge, B.,Wu, L.N.Y.,Wuthier, R.E.,Lebioda, L. Crystal Structures of Chicken Annexin A5 in Complex with Functional Modifiers Ca2+ and Zn2+ Reveal Zn2+ Induced Formation of Non-Planar Assemblies Annexins 2005 1 183 190
1YOC Crystal Structure of genomics APC5556 2005-01-27 2005-03-08 Dong, A.,Evdokimova, E.,Kudritskam, M.,Zhang, R.G.,Yakunin, A.,Pai, E.,Edwards, A.,Savchenko, A. Crystal structure of genomics AFPA1835 by Sulfur SAD methods To be Published 0 0 0 0
1YW6 Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72. 2005-02-17 2005-03-08 Forouhar, F.,Yong, W.,Kuzin, A.P.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72. To be Published 0 0 0 0
1YP2 15692569 Crystal structure of potato tuber ADP-glucose pyrophosphorylase 2005-01-29 2005-03-15 Jin, X.,Ballicora, M.A.,Preiss, J.,Geiger, J.H. Crystal structure of potato tuber ADP-glucose pyrophosphorylase. Embo J. 2005 24 694 704
1YQH Structure of domain of unknown function DUF77 from Bacillus cereus 2005-02-01 2005-03-15 Cuff, M.E.,Quartey, P.,Zhou, M.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Structure of domain of unknown function DUF77 from Bacillus cereus To be Published 0 0 0 0
1YTL Crystal Structure of Acetyl-CoA decarboxylase/synthase complex epsilon subunit 2 2005-02-10 2005-03-22 Chang, C.,Evdokimova, E.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal Structure of Acetyl-CoA decarboxylase/synthase complex epsilon subunit 2 from Archaeoglobus fulgidus To be Published 0 0 0 0
1YVO hypothetical acetyltransferase from P.aeruginosa PA01 2005-02-16 2005-03-29 Nocek, B.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of a hypothetical acetyltransferase from P.aeruginosa PA01 To be Published 0 0 0 0
1YX2 Crystal Structure of the Probable Aminomethyltransferase from Bacillus subtilis 2005-02-19 2005-04-05 Kim, Y.,Quartey, P.,Lezondra, L.,Collart, F.,Joachimiak, A. Crystal Structure of the Probable Aminomethyltransferase from Bacillus subtilis To be Published 0 0 0 0
1YXY Crystal Structure of putative N-acetylmannosamine-6-P epimerase from Streptococcus pyogenes (APC29713) Structural genomics, MCSG 2005-02-22 2005-04-05 Rotella, F.J.,Zhang, R.G.,Lezondra, L.E.O.,Collart, F.R.,Joachimiak, A. The 1.6 A crystal structure of putative N-acetylmannosamine-6-P epimerase from Streptococcus pyogenes To be Published 0 0 0 0
1YTV 16511036 Maltose-binding protein fusion to a C-terminal fragment of the V1a vasopressin receptor 2005-02-11 2005-04-12 Adikesavan, N.V.,Mahmood, S.S.,Stanley, N.,Xu, Z.,Wu, N.,Thibonnier, M.,Shoham, M. A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein. Acta Crystallogr.,Sect.F 2005 61 341 345
1TVB 15814707 Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2 2004-06-29 2005-04-19 Borbulevych, O.Y.,Baxter, T.K.,Yu, Z.,Restifo, N.P.,Baker, B.M. Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design J.Immunol. 2005 174 4812 4820
1TVH 15814707 Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2 2004-06-29 2005-04-19 Borbulevych, O.Y.,Baxter, T.K.,Yu, Z.,Restifo, N.P.,Baker, B.M. Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design J.Immunol. 2005 174 4812 4820
1Z0X Crystal structure of transcriptional regulator, tetR Family from Enterococcus faecalis V583 2005-03-02 2005-04-19 Chang, C.,Li, H.,Collart, F.,Moy, S.,Joachimiak, A. Crystal structure of transcriptional regulator, tetR Family from Enterococcus faecalis V583 To be Published 0 0 0 0
1Z84 16519510 X-ray structure of galt-like protein from arabidopsis thaliana at5g18200 2005-03-29 2005-04-19 MCCOY, J.G.,ARABSHAHI, A.,BITTO, E.,BINGMAN, C.A.,RUZICKA, F.J.,FREY, P.A.,PHILLIPS JR., G.N. Structure and Mechanism of an ADP-Glucose Phosphorylase from Arabidopsis thaliana Biochemistry 2006 45 3154 3162
1YOX Structure of the conserved Protein of Unknown Function PA3696 from Pseudomonas aeruginosa 2005-01-28 2005-04-26 Walker, J.R.,Xu, X.,Gu, J.,Savchenko, A. X-ray structure of the conserved hypothetical protein PA3696 To be Published 0 0 0 0
1Z67 16927377 Structure of Homeodomain-like Protein of Unknown Function S4005 from Shigella flexneri 2005-03-21 2005-05-03 Osipiuk, J.,Maltseva, N.,Dementieva, I.,Clancy, S.,Collart, F.,Joachimiak, A. Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif. Proteins 2006 65 509 513
1YMP 15802643 The Crystal Structure of a Partial Mouse Notch-1 Ankyrin Domain: Repeats 4 Through 7 Preserve an Ankyrin Fold 2005-01-21 2005-05-10 Lubman, O.Y.,Kopan, R.,Waksman, G.,Korolev, S. The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold. Protein Sci. 2005 14 1274 1281
1Z77 17588774 Crystal structure of transcriptional regulator protein from Thermotoga maritima. 2005-03-24 2005-05-10 Koclega, K.D.,Chruszcz, M.,Zimmerman, M.D.,Cymborowski, M.,Evdokimova, E.,Minor, W. Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment. J.Struct.Biol. 2007 159 424 432
1Z7A Crystal structure of probable Polysaccharide deacetylase from Pseudomonas aeruginosa PAO1 2005-03-24 2005-05-10 Chang, C.,Skarina, T.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of probable Polysaccharide deacetylase from Pseudomonas aeruginosa PAO1 To be Published 0 0 0 0
1Z7U Crystal Structure of the Putitive Transcriptional Regulator of MarR Family from Enterococcus faecalis V583 2005-03-28 2005-05-10 Kim, Y.,Wu, R.,Collart, F.,Joachimiak, A. Crystal Structure of the Putitive Transcriptional Regulator of MarR Family from Enterococcus faecalis To be Published 0 0 0 0
1Z9H 15854652 Microsomal prostaglandin E synthase type-2 2005-04-02 2005-05-17 Yamada, T.,Komoto, J.,Watanabe, K.,Ohmiya, Y.,Takusagawa, F. Crystal Structure and Possible Catalytic Mechanism of Microsomal Prostaglandin E Synthase Type 2 (mPGES-2). J.Mol.Biol. 2005 348 1163 1176
1TQ5 15951572 Crystal Structure of YhhW from Escherichia coli 2004-06-16 2005-06-14 Adams, M.,Jia, Z. Structural and biochemical analysis reveal pirins to possess quercetinase activity. J.Biol.Chem. 2005 280 28675 28682
1ZA3 15854651 The crystal structure of the YSd1 Fab bound to DR5 2005-04-05 2005-06-14 Fellouse, F.A.,Li, B.,Compaan, D.M.,Peden, A.A.,Hymowitz, S.G.,Sidhu, S.S. Molecular recognition by a binary code. J.Mol.Biol. 2005 348 1153 1162
1ZKI 22439787 Structure of conserved protein PA5202 from Pseudomonas aeruginosa 2005-05-02 2005-06-14 Gonzalez, C.F.,Tchigvintsev, A.,Brown, G.,Flick, R.,Evdokimova, E.,Xu, X.,Osipiuk, J.,Cuff, M.E.,Lynch, S.,Joachimiak, A.,Savchenko, A.,Yakunin, A.F. Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801. Biochem.J. 2012 444 445 455
1ZMA Crystal Structure of the Bacterocin Transport Accessory Protein from Streptococcus pneumoniae 2005-05-10 2005-06-21 Kim, Y.,Hatzos, C.,Abdullah, J.,Collart, F.,Joachimiak, A. The Crystal Structure of the Bacterocin Transport Accessory Protein from Streptococcus pneumoniae To be Published 0 0 0 0
1ZPV ACT domain protein from Streptococcus pneumoniae 2005-05-17 2005-06-28 Osipiuk, J.,Hatzos, C.,Abdullah, J.,Collart, F.,Joachimiak, A. X-ray crystal structure of ACT domain protein from Streptococcus pneumoniae To be Published 0 0 0 0
1ZS7 The structure of gene product APE0525 from Aeropyrum pernix 2005-05-23 2005-07-05 Cuff, M.E.,Skarina, T.,Edwards, A.,Savchenko, A.,Joachimiak, A. The structure of gene product APE0525 from Aeropyrum pernix To be Published 0 0 0 0
1ZWY Crystal structure of protein VC0702 from Vibrio cholerae 2005-06-06 2005-07-19 Chang, C.,Wu, R.,Moy, S.,Joachimiak, A. Crystal structure of protein VC0702 from Vibrio cholerae To be Published 0 0 0 0
1ZX3 Structure of NE0241 Protein of Unknown Function from Nitrosomonas europaea 2005-06-06 2005-07-19 Osipiuk, J.,Cuff, M.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A. X-ray crystal structure of hypothetical protein NE0241 from Nitrosomonas europaea. To be Published 0 0 0 0
2A5J Crystal Structure of Human RAB2B 2005-06-30 2005-07-19 Wang, J.,Dong, A.,Shen, Y.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Bochkarev, A.,Park, H.W. Crystal structure of human RAB2B To be Published 0 0 0 0
2A61 The crystal structure of transcriptional regulator Tm0710 from Thermotoga maritima 2005-07-01 2005-07-19 Lunin, V.V.,Evdokimova, E.,Kudritska, M.,Chang, C.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of transcriptional regulator Tm0710 from Thermotoga maritima To be Published 0 0 0 0
2A9S The crystal structure of competence/damage inducible protein CihA from Agrobacterium tumefaciens 2005-07-12 2005-07-19 Lunin, V.V.,Evdokimova, E.,Kudritska, M.,Kim, Y.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of competence/damage inducible protein CihA from Agrobacterium tumefaciens To be Published 0 0 0 0
2A2C 16006554 x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 2005-06-22 2005-07-26 Thoden, J.B.,Holden, H.M. The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem. 2005 280 32784 32791
1ZOT 16138079 crystal structure analysis of the CyaA/C-Cam with PMEAPP 2005-05-13 2005-08-09 Guo, Q.,Shen, Y.,Lee, Y.S.,Gibbs, C.S.,Mrksich, M.,Tang, W.J. Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin. Embo J. 2005 24 3190 3201
2A5Z 18566914 Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1 2005-07-01 2005-08-16 Nocek, B.,Bigelow, L.,Abdullah, J.,Joachimiak, A. Structure of SO2946 orphan from Shewanella oneidensis shows ""jelly-roll"" fold with carbohydrate-binding module. J.STRUCT.FUNCT.GENOM. 2008 9 1 6
2A67 Crystal structure of Isochorismatase family protein 2005-07-01 2005-08-16 Chang, C.,Hatzos, C.,Collart, F.,Moy, S.,Joachimiak, A. Crystal structure of Isochorismatase family protein To be Published 0 0 0 0
2A9U 17035239 Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) 2005-07-12 2005-08-16 Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem. 2006 281 38061 38070
1XI2 16129418 Quinone Reductase 2 in Complex with Cancer Prodrug CB1954 2004-09-21 2005-08-30 Fu, Y.,Buryanovskyy, L.,Zhang, Z. Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954 Biochem.Biophys.Res.Commun. 2005 336 332 338
1ZTW 16049022 d(CTTAATTCGAATTAAG) complexed with Moloney Murine Leukemia Virus Reverse Transcriptase catalytic fragment 2005-05-27 2005-08-30 Goodwin, K.D.,Long, E.C.,Georgiadis, M.M. A host-guest approach for determining drug-DNA interactions: an example using netropsin. Nucleic Acids Res. 2005 33 4106 4116
2ARY 17157313 Catalytic domain of Human Calpain-1 2005-08-22 2005-08-30 Davis, T.L.,Walker, J.R.,Finerty, P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition J.Mol.Biol. 2007 366 216 229
2A4A 17125854 Deoxyribose-phosphate aldolase from P. yoelii 2005-06-28 2005-09-06 Vedadi, M.,Lew, J.,Artz, J.,Amani, M.,Zhao, Y.,Dong, A.,Wasney, G.A.,Gao, M.,Hills, T.,Brokx, S.,Qiu, W.,Sharma, S.,Diassiti, A.,Alam, Z.,Melone, M.,Mulichak, A.,Wernimont, A.,Bray, J.,Loppnau, P.,Plotnikova, O.,Newberry, K.,Sundararajan, E.,Houston, S.,Walker, J.,Tempel, W.,Bochkarev, A.,Kozieradzki, I.,Edwards, A.,Arrowsmith, C.,Roos, D.,Kain, K.,Hui, R. Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol. 2007 151 100 110
2AEE Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes 2005-07-22 2005-09-06 Chang, C.,Li, H.,Collart, F.,Joachimiak, A. Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes To be Published 0 0 0 0
1TXQ 16109370 Crystal structure of the EB1 C-terminal domain complexed with the CAP-Gly domain of p150Glued 2004-07-06 2005-09-13 Hayashi, I.,Wilde, A.,Mal, T.K.,Ikura, M. Structural Basis for the Activation of Microtubule Assembly by the EB1 and p150(Glued) Complex Mol.Cell 2005 19 449 460
1XWF 16061414 K185N mutated S-adenosylhomocysteine hydrolase 2004-11-01 2005-09-20 Yamada, T.,Takata, Y.,Komoto, J.,Gomi, T.,Ogawa, H.,Fujioka, M.,Takusagawa, F. Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89. Int.J.Biochem.Cell Biol. 2005 37 2417 2435
2AS0 16260766 Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase 2005-08-22 2005-09-20 Sun, W.,Xu, X.,Pavlova, M.,Edwards, A.M.,Joachimiak, A.,Savchenko, A.,Christendat, D. The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii. Protein Sci. 2005 14 3121 3128
2AP1 Crystal structure of the putative regulatory protein 2005-08-15 2005-09-27 Brunzelle, J.S.,Minasov, G.,Shuvalova, L.,Collart, F.R.,Anderson, W.F. Crystal structure of the putative regulatory protein To be Published 0 0 0 0
1ZPU 16230618 Crystal Structure of Fet3p, a Multicopper Oxidase that Functions in Iron Import 2005-05-17 2005-10-04 Taylor, A.B.,Stoj, C.S.,Ziegler, L.,Kosman, D.J.,Hart, P.J. The copper-iron connection in biology: Structure of the metallo-oxidase Fet3p. Proc.Natl.Acad.Sci.Usa 2005 102 15459 15464
1ZPU 16230618 Crystal Structure of Fet3p, a Multicopper Oxidase that Functions in Iron Import 2005-05-17 2005-10-04 Taylor, A.B.,Stoj, C.S.,Ziegler, L.,Kosman, D.J.,Hart, P.J. The copper-iron connection in biology: Structure of the metallo-oxidase Fet3p. Proc.Natl.Acad.Sci.Usa 2005 102 15459 15464
2ATR Acetyltransferase, GNAT family protein SP0256 from Streptococcus pneumoniae TIGR4 2005-08-25 2005-10-11 Binkowski, T.A.,Hatzos, C.,Abdullah, J.,Collart, F.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Acetyltransferase, GNAT family protein SP0256 from Streptococcus pneumoniae To be Published 0 0 0 0
2AV1 16197958 Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the E63Q and K66A mutations in the heavy chain. 2005-08-29 2005-10-18 Gagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Baxter, T.K.,Clemens, J.R.,Armstrong, K.M.,Turner, R.V.,Damirjian, M.,Biddison, W.E.,Baker, B.M. Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants. J.Mol.Biol. 2005 353 556 573
2AV7 16197958 Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain. 2005-08-29 2005-10-18 Gagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Baxter, T.K.,Clemens, J.R.,Armstrong, K.M.,Turner, R.V.,Damirjian, M.,Biddison, W.E.,Baker, B.M. Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants. J.Mol.Biol. 2005 353 556 573
2AV9 19898606 Crystal Structure of the PA5185 protein from Pseudomonas Aeruginosa Strain PAO1. 2005-08-29 2005-10-18 Chruszcz, M.,Zimmerman, M.D.,Wang, S.,Koclega, K.D.,Zheng, H.,Evdokimova, E.,Kudritska, M.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Minor, W. Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1. Cryst.Growth Des. 2008 8 4054 4061
2AEM 16227203 Crystal Structures of the MthK RCK Domain 2005-07-22 2005-10-25 Dong, J.,Shi, N.,Berke, I.,Chen, L.,Jiang, Y. Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability J.Biol.Chem. 2005 280 41716 41724
2ARK Structure of a flavodoxin from Aquifex aeolicus 2005-08-19 2005-10-25 Cuff, M.E.,Quartey, P.,Zhou, M.,Cymborowski, M.,Minor, W.,Joachimiak, A. Structure of a flavodoxin from Aquifex aeolicus To be Published 0 0 0 0
2ESN The crystal structure of probable transcriptional regulator PA0477 from Pseudomonas aeruginosa 2005-10-26 2005-11-01 Lunin, V.V.,Chang, C.,Skarina, T.,Gorodischenskaya, E.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of putative transcriptional regulator Pa0477 from Pseudomonas aeruginosa To be Published 0 0 0 0
2ESN The crystal structure of probable transcriptional regulator PA0477 from Pseudomonas aeruginosa 2005-10-26 2005-11-01 Lunin, V.V.,Chang, C.,Skarina, T.,Gorodischenskaya, E.,Joachimiak, A.,Edwards, A.,Savchenko, A. The crystal structure of putative transcriptional regulator Pa0477 from Pseudomonas aeruginosa To be Published 0 0 0 0
2ESK 16365295 Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b, wild-type 2005-10-26 2005-12-06 Ozkan, E.,Yu, H.,Deisenhofer, J. Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa 2005 102 18890 18895
2ESO 16365295 Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b mutant Ile37Ala 2005-10-26 2005-12-06 Ozkan, E.,Yu, H.,Deisenhofer, J. Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa 2005 102 18890 18895
2ESP 16365295 Human ubiquitin-conjugating enzyme (E2) UbcH5b mutant Ile88Ala 2005-10-26 2005-12-06 Ozkan, E.,Yu, H.,Deisenhofer, J. Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa 2005 102 18890 18895
2ESQ 16365295 Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b mutant Ser94Gly 2005-10-26 2005-12-06 Ozkan, E.,Yu, H.,Deisenhofer, J. Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa 2005 102 18890 18895
1Y4K 16922498 Lipoxygenase-1 (Soybean) at 100K, N694G Mutant 2004-12-01 2005-12-13 Segraves, E.N.,Chruszcz, M.,Neidig, M.L.,Ruddat, V.,Zhou, J.,Wecksler, A.T.,Minor, W.,Solomon, E.I.,Holman, T.R. Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly. Biochemistry 2006 45 10233 10242
2AWN 16326809 Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ATP-Mg) 2005-09-01 2005-12-13 Lu, G.,Westbrooks, J.M.,Davidson, A.L.,Chen, J. ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation. Proc.Natl.Acad.Sci.Usa 2005 102 17969 17974
2AWO 16326809 Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ADP-Mg) 2005-09-01 2005-12-13 Lu, G.,Westbrooks, J.M.,Davidson, A.L.,Chen, J. ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation. Proc.Natl.Acad.Sci.Usa 2005 102 17969 17974
2ESL 20676357 Human Cyclophilin C in Complex with Cyclosporin A 2005-10-26 2005-12-13 Davis, T.L.,Walker, J.R.,Campagna-Slater, V.,Finerty, P.J.,Paramanathan, R.,Bernstein, G.,MacKenzie, F.,Tempel, W.,Ouyang, H.,Lee, W.H.,Eisenmesser, E.Z.,Dhe-Paganon, S. Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol. 2010 8 0 0
2EVV Crystal Structure of the PEBP-like Protein of Unknown Function HP0218 from Helicobacter pylori 2005-11-01 2005-12-13 Kim, Y.,Xu, X.,Hong, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal Structure of the Hypothetical Protein HP0218 from Helicobacter pylori To be Published 0 0 0 0
2FAZ Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95 2005-12-08 2005-12-20 Walker, J.R.,Wybenga-Groot, L.,Doherty, R.S.,Finerty Jr., P.J.,Newman, E.,Mackenzie, F.M.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S. Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95 To be Published 0 0 0 0
2F4W 22496338 Human ubiquitin-conjugating enzyme E2 J2 2005-11-24 2005-12-27 Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics 2012 11 329 341
2FBR 14583036 Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker) 2005-12-09 2005-12-27 Green, N.S.,Palaninathan, S.K.,Sacchettini, J.C.,Kelly, J.W. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. J.Am.Chem.Soc. 2003 125 13404 13414
2D7V Structure of OsmC-like Protein of Unknown Function VCA0330 from Vibrio cholerae O1 biovar eltor str. N16961 2005-11-30 2006-01-10 Binkowski, T.A.,Hatzos, C.,Moy, S.,Collart, F.,Joachimiak, A. Hypothetical protein VCA0330 from Vibrio cholerae O1 biovar eltor str. N16961 TO BE PUBLISHED 0 0 0 0
2FA1 16672238 Crystal structure of PhnF C-terminal domain 2005-12-06 2006-01-10 Gorelik, M.,Lunin, V.V.,Skarina, T.,Savchenko, A. Structural characterization of GntR/HutC family signaling domain. Protein Sci. 2006 15 1 6
1YTY 16387655 Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen 2005-02-11 2006-01-17 Teplova, M.,Yuan, Y.R.,Phan, A.T.,Malinina, L.,Ilin, S.,Teplov, A.,Patel, D.J. Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell 2006 21 75 85
2F9H The Crystal Structure of PTS System IIA Component from Enterococcus faecalis V583 2005-12-05 2006-01-17 Kim, Y.,Quartey, P.,Abdullah, J.,Collart, F.,Joachimiak, A. The Crystal Structure of PTS System IIA Component from Enterococcus faecalis V583 To be Published 2006 0 0 0
2FFC 17125854 Crystal Structure of Plasmodium Vivax Orotidine-Monophosphate-Decarboxyl UMP Bound 2005-12-19 2006-01-17 Vedadi, M.,Lew, J.,Artz, J.,Amani, M.,Zhao, Y.,Dong, A.,Wasney, G.A.,Gao, M.,Hills, T.,Brokx, S.,Qiu, W.,Sharma, S.,Diassiti, A.,Alam, Z.,Melone, M.,Mulichak, A.,Wernimont, A.,Bray, J.,Loppnau, P.,Plotnikova, O.,Newberry, K.,Sundararajan, E.,Houston, S.,Walker, J.,Tempel, W.,Bochkarev, A.,Kozieradzki, I.,Edwards, A.,Arrowsmith, C.,Roos, D.,Kain, K.,Hui, R. Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol. 2007 151 100 110
2FHX 16460758 Pseudomonas aeruginosa SPM-1 metallo-beta-lactamase 2005-12-27 2006-01-17 Murphy, T.A.,Catto, L.E.,Halford, S.E.,Hadfield, A.T.,Minor, W.,Walsh, T.R.,Spencer, J. Crystal Structure of Pseudomonas aeruginosa SPM-1 Provides Insights into Variable Zinc Affinity of Metallo-beta-lactamases. J.Mol.Biol. 2006 357 890 903
2COL 16138079 Crystal structure analysis of CyaA/C-Cam with Pyrophosphate 2005-05-18 2006-01-24 Guo, Q.,Shen, Y.,Lee, Y.S.,Gibbs, C.S.,Mrksich, M.,Tang, W.J. Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin Embo J. 2005 24 3190 3201
2D9R Structure of Conserved Protein of Unknown Function PG0164 from Porphyromonas gingivalis [W83] 2005-12-13 2006-01-24 Binkowski, T.A.,Hatzos, C.,Moy, S.,Collart, F.,Joachimiak, A. Conserved hypothetical protein PG0164 frpm Porphyromonas gingivalis [W83] To be published 0 0 0 0
2FEX The Crystal Structure of DJ-1 Superfamily Protein Atu0886 from Agrobacterium tumefaciens 2005-12-16 2006-01-31 Cymborowski, M.T.,Wang, S.,Chruszcz, M.,Shumilin, I.,Gu, J.,Xu, X.,Edwards, A.M.,Savchenko, A.,Minor, W. The Crystal Structure of DJ-1 Superfamily Protein Atu0886 from Agrobacterium tumefaciens To be Published 0 0 0 0
2FM1 Crystal structure of L-ALLO-threonine aldolase (tm1744) from Thermotoga maritima at 2.25 A resolution 2006-01-06 2006-01-31 Joint Center for Structural Genomics (JCSG) Crystal structure of L-ALLO-threonine aldolase (tm1744) from Thermotoga maritima at 2.25 A resolution To be published 0 0 0 0
2AHZ 16467789 K+ complex of the NaK Channel 2005-07-28 2006-02-07 Shi, N.,Ye, S.,Alam, A.,Chen, L.,Jiang, Y. Atomic structure of a Na+- and K+-conducting channel. Nature 2006 440 570 574
2FGC 17586771 Crystal structure of Acetolactate synthase- small subunit from Thermotoga maritima 2005-12-21 2006-02-07 Petkowski, J.J.,Chruszcz, M.,Zimmerman, M.D.,Zheng, H.,Skarina, T.,Onopriyenko, O.,Cymborowski, M.T.,Koclega, K.D.,Savchenko, A.,Edwards, A.,Minor, W. Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit. Protein Sci. 2007 16 1360 1367
2FIW Crystal Structure of the GCN5-Related N-acetyltransferase: Aminotransferase, Class-II from Rhodopseudomonas palustris 2005-12-30 2006-02-14 Kim, Y.,Skarina, T.,Onopriyenko, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal Structure of the GCN5-Related N-acetyltransferase: Aminotransferase, Class-II from Rhodopseudomonas palustris To be Published 2006 0 0 0
2FNO 16988933 Crystal structure of a glutathione s-transferase (atu5508) from agrobacterium tumefaciens str. c58 at 2.00 A resolution 2006-01-11 2006-02-14 Kosloff, M.,Han, G.W.,Krishna, S.S.,Schwarzenbacher, R.,Fasnacht, M.,Elsliger, M.A.,Abdubek, P.,Agarwalla, S.,Ambing, E.,Astakhova, T.,Axelrod, H.L.,Canaves, J.M.,Carlton, D.,Chiu, H.J.,Clayton, T.,DiDonato, M.,Duan, L.,Feuerhelm, J.,Grittini, C.,Grzechnik, S.K.,Hale, J.,Hampton, E.,Haugen, J.,Jaroszewski, L.,Jin, K.K.,Johnson, H.,Klock, H.E.,Knuth, M.W.,Koesema, E.,Kreusch, A.,Kuhn, P.,Levin, I.,McMullan, D.,Miller, M.D.,Morse, A.T.,Moy, K.,Nigoghossian, E.,Okach, L.,Oommachen, S.,Page, R.,Paulsen, J.,Quijano, K.,Reyes, R.,Rife, C.L.,Sims, E.,Spraggon, G.,Sridhar, V.,Stevens, R.C.,van den Bedem, H.,Velasquez, J.,White, A.,Wolf, G.,Xu, Q.,Hodgson, K.O.,Wooley, J.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A. Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Proteins 2006 65 527 537
1WCI 16472748 Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch 2004-11-16 2006-02-16 Machius, M.,Wynn, R.M.,Chuang, J.L.,Li, J.,Kluger, R.,Yu, D.,Tomchick, D.R.,Brautigam, C.A.,Chuang, D.T. A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure 2006 14 287 0
2BEU 16472748 Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch 2004-11-30 2006-02-16 Machius, M.,Wynn, R.M.,Chuang, J.L.,Li, J.,Kluger, R.,Yu, D.,Tomchick, D.R.,Brautigam, C.A.,Chuang, D.T. A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure 2006 14 287 0
2BEW 16472748 Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch 2004-11-30 2006-02-16 Machius, M.,Wynn, R.M.,Chuang, J.L.,Li, J.,Kluger, R.,Yu, D.,Tomchick, D.R.,Brautigam, C.A.,Chuang, D.T. A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure 2006 14 287 0
2G3A Crystal structure of putative acetyltransferase from Agrobacterium tumefaciens 2006-02-17 2006-03-14 Cymborowski, M.,Xu, X.,Chruszcz, M.,Zheng, H.,Gu, J.,Savchenko, A.,Edwards, A.,Minor, W. Crystal structure of putative acetyltransferase from Agrobacterium tumefaciens To be Published 0 0 0 0
2G3B Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. 2006-02-17 2006-03-14 Chruszcz, M.,Evdokimova, E.,Cymborowski, M.,Kagan, O.,Wang, S.,Koclega, K.D.,Savchenko, A.,Edwards, A.,Minor, W. Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. To be Published 0 0 0 0
2G03 Structure of a putative cell filamentation protein from Neisseria meningitidis. 2006-02-10 2006-03-21 Cuff, M.E.,Bigelow, L.,Bargassa, M.,Joachimiak, A. Structure of a putative cell filamentation protein from Neisseria meningitidis. To be Published 0 0 0 0
2F2F 16434747 Crystal structure of cytolethal distending toxin (CDT) from Actinobacillus actinomycetemcomitans 2005-11-16 2006-03-28 Yamada, T.,Komoto, J.,Saiki, K.,Konishi, K.,Takusagawa, F. Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans Protein Sci. 2006 15 362 372
2FH9 16531232 Structure and dimerization of the kinase domain from yeast Snf1 2005-12-23 2006-03-28 Nayak, V.,Zhao, K.,Wyce, A.,Schwartz, M.F.,Lo, W.S.,Berger, S.L.,Marmorstein, R. Structure and Dimerization of the Kinase Domain from Yeast Snf1, a Member of the Snf1/AMPK Protein Family Structure 2006 14 477 485
2FZP 17035239 Crystal structure of the USP8 interaction domain of human NRDP1 2006-02-10 2006-03-28 Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem. 2006 281 38061 38070
2G2C Putative molybdenum cofactor biosynthesis protein from Corynebacterium diphtheriae. 2006-02-15 2006-03-28 Osipiuk, J.,Li, H.,Clancy, S.,Joachimiak, A. X-ray crystal structure of putative molybdenum cofactor biosynthesis protein from Corynebacterium diphtheriae. To be Published 0 0 0 0
2ER8 16615914 Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex 2005-10-24 2006-04-04 Fitzgerald, M.X.,Rojas, J.R.,Kim, J.M.,Kohlhaw, G.B.,Marmorstein, R. Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure 2006 14 725 735
2G7R X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 2006-02-28 2006-04-04 Wybenga-Groot, L.,Walker, J.R.,Newman, E.M.,Finerty Jr., P.J.,Butler-Cole, C.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S. X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 To be Published 0 0 0 0
2G7U 2.3 A structure of putative catechol degradative operon regulator from Rhodococcus sp. RHA1 2006-03-01 2006-04-04 Zheng, H.,Skarina, T.,Chruszcz, M.,Cymborowski, M.,Grabowski, M.,Onopriyenko, O.,Savchenko, A.,Edwards, A.,Minor, W. 2.3 A structure of putative catechol degradative operon regulator from Rhodococcus sp. RHA1 To be Published 0 0 0 0
2GFO 17035239 Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8 2006-03-22 2006-04-04 Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem. 2006 281 38061 38070
2F9S 16537372 2nd Crystal Structure Of A Soluble Domain Of ResA In The Oxidised Form 2005-12-06 2006-04-18 Colbert, C.L.,Wu, Q.,Erbel, P.J.A.,Gardner, K.H.,Deisenhofer, J. Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation Proc.Natl.Acad.Sci.USA 2006 103 4410 4415
2F9S 16537372 2nd Crystal Structure Of A Soluble Domain Of ResA In The Oxidised Form 2005-12-06 2006-04-18 Colbert, C.L.,Wu, Q.,Erbel, P.J.A.,Gardner, K.H.,Deisenhofer, J. Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation Proc.Natl.Acad.Sci.USA 2006 103 4410 4415
2GKP Protein of Unknown Function NMB0488 from Neisseria meningitidis 2006-04-03 2006-05-02 Osipiuk, J.,Volkart, L.,Bargassa, M.,Joachimiak, A. X-ray crystal structure of hypothetical protein NMB0488 from Neisseria meningitidis. To be Published 0 0 0 0
1ZKY 16648639 Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-3M and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide 2005-05-04 2006-05-09 Hsieh, R.W.,Rajan, S.S.,Sharma, S.K.,Guo, Y.,Desombre, E.R.,Mrksich, M.,Greene, G.L. Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem. 2006 281 17909 17919
2GU3 YpmB protein from Bacillus subtilis 2006-04-28 2006-05-30 Osipiuk, J.,Maltseva, N.,Dementieva, I.,Moy, S.,Joachimiak, A. X-ray crystal structure of YpmB protein from Bacillus subtilis. To be Published 0 0 0 0
2GUH Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1 2006-04-30 2006-05-30 Kim, Y.,Joachimiak, A.,Skarina, T.,Zheng, H.,Edwards, A.,Savchenko, A. Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1 To be Published 0 0 0 0
2H1I Crystal Structure of the Bacillus cereus Carboxylesterase 2006-05-16 2006-05-30 Minasov, G.,Shuvalova, L.,Collart, F.R.,Anderson, W.F. Crystal Structure of the Bacillus cereus Carboxylesterase To be Published 0 0 0 0
2GWN The structure of putative dihydroorotase from Porphyromonas gingivalis. 2006-05-04 2006-06-06 Cuff, M.E.,Borovilos, M.,Moy, S.,Joachimiak, A. The structure of putative dihydroorotase from Porphyromonas gingivalis. To be Published 0 0 0 0
2CJT 16732694 Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules 2006-04-06 2006-06-07 Lu, J.,Machius, M.,Dulubova, I.,Dai, H.,Sudhof, T.C.,Tomchick, D.R.,Rizo, J. Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch Plos Biol. 2006 4 0 0
2GYQ YcfI, a putative structural protein from Rhodopseudomonas palustris. 2006-05-09 2006-06-13 Osipiuk, J.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.,Joachimiak, A. X-ray crystal structure of YcfI protein, a putative structural protein from Rhodopseudomonas palustris. To be Published 0 0 0 0
2AM3 16769084 Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-Glucose 2005-08-08 2006-06-27 Gordon, R.D.,Sivarajah, P.,Satkunarajah, M.,Ma, D.,Tarling, C.A.,Vizitiu, D.,Withers, S.G.,Rini, J.M. X-ray Crystal Structures of Rabbit N-acetylglucosaminyltransferase I (GnT I) in Complex with Donor Substrate Analogues. J.Mol.Biol. 2006 360 67 79
2AM5 16769084 Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP 2005-08-08 2006-06-27 Gordon, R.D.,Sivarajah, P.,Satkunarajah, M.,Ma, D.,Tarling, C.A.,Vizitiu, D.,Withers, S.G.,Rini, J.M. X-ray Crystal Structures of Rabbit N-acetylglucosaminyltransferase I (GnT I) in Complex with Donor Substrate Analogues. J.Mol.Biol. 2006 360 67 79
2GPH 16765894 Docking motif interactions in the MAP kinase ERK2 2006-04-17 2006-07-04 Zhou, T.,Sun, L.,Humphreys, J.,Goldsmith, E.J. Docking Interactions Induce Exposure of Activation Loop in the MAP Kinase ERK2. Structure 2006 14 1011 1019
2G29 16777960 crystal structure of the periplasmic nitrate-binding protein NrtA from Synechocystis PCC 6803 2006-02-15 2006-07-11 Koropatkin, N.M.,Pakrasi, H.B.,Smith, T.J. Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity Proc.Natl.Acad.Sci.Usa 2006 103 9820 9825
2GAM 16829524 X-ray crystal structure of murine leukocyte-type Core 2 b1,6-N-acetylglucosaminyltransferase (C2GnT-L) in complex with Galb1,3GalNAc 2006-03-09 2006-07-11 Pak, J.E.,Arnoux, P.,Zhou, S.,Sivarajah, P.,Satkunarajah, M.,Xing, X.,Rini, J.M. X-ray Crystal Structure of Leukocyte Type Core 2 beta1,6-N-Acetylglucosaminyltransferase: Evidence for a covergence of metal ion independent glycosyltransferase mechanism. J.Biol.Chem. 2006 281 26693 26701
2GTD 16855243 Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria 2006-04-27 2006-08-01 Yang, K.,Eyobo, Y.,Brand, L.A.,Martynowski, D.,Tomchick, D.,Strauss, E.,Zhang, H. Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria. J.Bacteriol. 2006 188 5532 5540
2GTD 16855243 Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria 2006-04-27 2006-08-01 Yang, K.,Eyobo, Y.,Brand, L.A.,Martynowski, D.,Tomchick, D.,Strauss, E.,Zhang, H. Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria. J.Bacteriol. 2006 188 5532 5540
2HKU Structural Genomics, the crystal structure of a putative transcriptional regulator from Rhodococcus sp. RHA1 2006-07-05 2006-08-08 Tan, K.,Evdokimova, E.,Kagan, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of a transcriptional regulator from Rhodococcus sp. RHA1 To be Published 0 0 0 0
2HMC The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens 2006-07-11 2006-09-05 Kim, Y.,Zhang, R.,Xu, X.,Zheng, H.,Edwards, A.,Savchenko, A.,Joachimiak, A. The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens To be Published 2006 0 0 0
2HXI Structural Genomics, the crystal structure of a putative transcriptional regulator from Streptomyces coelicolor A3(2) 2006-08-03 2006-09-05 Tan, K.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of a putative transcriptional regulator TetR from Streptomyces coelicolor A3(2) To be Published 0 0 0 0
2EWS 16905099 Crystal structure of S.aureus pantothenate kinase 2005-11-06 2006-09-12 Hong, B.S.,Yun, M.K.,Zhang, Y.M.,Chohnan, S.,Rock, C.O.,White, S.W.,Jackowski, S.,Park, H.W.,Leonardi, R. Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties. Structure 2006 14 1251 1261
2EWS 16905099 Crystal structure of S.aureus pantothenate kinase 2005-11-06 2006-09-12 Hong, B.S.,Yun, M.K.,Zhang, Y.M.,Chohnan, S.,Rock, C.O.,White, S.W.,Jackowski, S.,Park, H.W.,Leonardi, R. Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties. Structure 2006 14 1251 1261
2FRS 16979656 Crystal structure of the f15w mutant of apo-cellular retinoic acid binding protein type ii at 1.51 angstroms resolution 2006-01-20 2006-09-19 Vaezeslami, S.,Mathes, E.,Vasileiou, C.,Borhan, B.,Geiger, J.H. The structure of Apo-wild-type cellular retinoic acid binding protein II at 1.4 A and its relationship to ligand binding and nuclear translocation. J.Mol.Biol. 2006 363 687 701
2I0M Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae 2006-08-10 2006-09-19 Zhang, R.,Li, H.,Abdullah, J.,Joachimiak, A. Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae To be Published 2006 0 0 0
2I3H 17168540 Structure of an ML-IAP/XIAP chimera bound to a 4-mer peptide (AVPW) 2006-08-18 2006-09-19 Zobel, K.,Wang, L.,Varfolomeev, E.,Franklin, M.C.,Elliott, L.O.,Wallweber, H.J.,Okawa, D.C.,Flygare, J.A.,Vucic, D.,Fairbrother, W.J.,Deshayes, K. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. Acs Chem.Biol. 2006 1 525 533
2I8E 18482976 Structure of SSO1404, a predicted DNA repair-associated protein from Sulfolobus solfataricus P2 2006-09-01 2006-09-26 Beloglazova, N.,Brown, G.,Zimmerman, M.D.,Proudfoot, M.,Makarova, K.S.,Kudritska, M.,Kochinyan, S.,Wang, S.,Chruszcz, M.,Minor, W.,Koonin, E.V.,Edwards, A.M.,Savchenko, A.,Yakunin, A.F. A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats. J.Biol.Chem. 2008 283 20361 20371
2IAI Crystal structure of SCO3833, a member of the TetR transcriptional regulator family from Streptomyces coelicolor A3 2006-09-08 2006-09-26 Zimmerman, M.D.,Xu, X.,Wang, S.,Gu, J.,Chruszcz, M.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Minor, W. Crystal structure of SCO3833, a member of the TetR transcriptional regulator family from Streptomyces coelicolor A3 To be Published 0 0 0 0
2GJ6 16962135 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide 2006-03-30 2006-10-03 Gagnon, S.J.,Borbulevych, O.Y.,Davis-Harrison, R.L.,Turner, R.V.,Damirjian, M.,Wojnarowicz, A.,Biddison, W.E.,Baker, B.M. T Cell Receptor Recognition via Cooperative Conformational Plasticity. J.Mol.Biol. 2006 363 228 243
2I71 Crystal structure of a Conserved Protein of Unknown Function from Sulfolobus solfataricus P2 2006-08-30 2006-10-03 Tan, K.,Skarina, T.,Onopriyenko, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of a Conserved hypothetical protein from Sulfolobus solfataricus P2 To be Published 0 0 0 0
2I7G Crystal Structure of Monooxygenase from Agrobacterium tumefaciens 2006-08-30 2006-10-03 Kim, Y.,Xu, X.,Zheng, H.,Joachimiak, A.,Edwards, A.,Savchenko, A. The Crystal Structure of Monooxygenase from Agrobacterium tumefaciens To be Published 2006 0 0 0
2I7H Crystal Structure of the Nitroreductase-like Family Protein from Bacillus cereus 2006-08-30 2006-10-03 Kim, Y.,Li, H.,Moy, S.,Joachimiak, A. Crystal Structure of the Nitroreductase-like Family Protein from Bacillus cereus To be Published 0 0 0 0
2I9C Crystal Structure of the Protein RPA1889 from Rhodopseudomonas palustris CGA009 2006-09-05 2006-10-03 Cymborowski, M.T.,Evdokimova, E.,Kagan, O.,Chruszcz, M.,Savchenko, A.,Edwards, A.,Minor, W. Crystal Structure of the Protein RPA1889 from Rhodopseudomonas palustris CGA009 To be Published 0 0 0 0
2I9X Structural Genomics, the crystal structure of SpoVG conserved domain from Staphylococcus epidermidis ATCC 12228 2006-09-06 2006-10-03 Tan, K.,Maltseva, N.,Bargassa, M.,Joachimiak, A. The crystal structure of SpoVG from Staphylococcus epidermidis ATCC 12228 To be Published 0 0 0 0
2I79 The crystal structure of the acetyltransferase of GNAT family from Streptococcus pneumoniae 2006-08-30 2006-10-10 Zhang, R.G.,Zhou, M.,Abdullah, J.,Joachimiak, A. The crystal structure of the acetyltransferase of GNAT family from Streptococcus pneumoniae To be Published 0 0 0 0
2I4S 16978643 PDZ domain of EpsC from Vibrio cholerae, residues 204-305 2006-08-22 2006-10-17 Korotkov, K.V.,Krumm, B.,Bagdasarian, M.,Hol, W.G. Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae. J.Mol.Biol. 2006 363 311 321
2I7R conserved domain protein 2006-08-31 2006-10-17 Duke, N.E.C.,Zhou, M.,Abdullah, J.,Joachimiak, A. conserved domain protein To be Published 0 0 0 0
2ID3 Crystal structure of transcriptional regulator SCO5951 from Streptomyces coelicolor A3(2) 2006-09-14 2006-10-17 0 0 0 0
2B02 Crystal Structure of ARNT PAS-B Domain 2005-09-12 2006-10-24 Lee, J.,Botuyan, M.V.,Nomine, Y.,Ohh, M.,Thompson, J.R.,Mer, G. Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain To be Published 0 0 0 0
2F6G 17291527 BenM effector binding domain 2005-11-29 2006-10-31 Ezezika, O.C.,Haddad, S.,Clark, T.J.,Neidle, E.L.,Momany, C. Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol. 2007 367 616 629
2F78 17291527 BenM effector binding domain with its effector benzoate 2005-11-30 2006-10-31 Ezezika, O.C.,Haddad, S.,Clark, T.J.,Neidle, E.L.,Momany, C. Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol. 2007 367 616 629
2F7A 17291527 BenM effector binding domain with its effector, cis,cis-muconate 2005-11-30 2006-10-31 Ezezika, O.C.,Haddad, S.,Clark, T.J.,Neidle, E.L.,Momany, C. Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol. 2007 367 616 629
2F7B 17291527 CatM effector binding domain 2005-11-30 2006-10-31 Ezezika, O.C.,Haddad, S.,Clark, T.J.,Neidle, E.L.,Momany, C. Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol. 2007 367 616 629
2F7C 17291527 CatM effector binding domain with its effector cis,cis-muconate 2005-11-30 2006-10-31 Ezezika, O.C.,Haddad, S.,Clark, T.J.,Neidle, E.L.,Momany, C. Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol. 2007 367 616 629
2IL5 Structure of Protein of Unknown Function SA2116 from Staphylococcus aureus 2006-10-02 2006-10-31 Osipiuk, J.,Quartey, P.,Holzle, D.,Joachimiak, A. X-ray crystal structure of hypothetical protein SA2116 from Staphylococcus aureus. To be Published 0 0 0 0
2B5U Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein 2005-09-29 2006-11-07 Nallini Vijayarangan, A.,Nithianantham, S.,Nan, W.,Jakes, K.,Shoham, M. Crystal Structure Of Colicin E3 In Complex With Its Immunity Protein TO BE PUBLISHED 0 0 0 0
2HZP 17300176 Crystal Structure of Homo Sapiens Kynureninase 2006-08-09 2006-11-07 Lima, S.,Khristoforov, R.,Momany, C.,Phillips, R.S. Crystal Structure of Homo sapiens Kynureninase. Biochemistry 2007 46 2735 2744
2IQT Crystal Structure of Fructose-Bisphosphate Aldolase, Class I from Porphyromonas gingivalis 2006-10-14 2006-11-14 Kim, Y.,Zhou, M.,Moy, S.,Joachimiak, A. Crystal Structure of Fructose-Bisphosphate Aldolase, Class I from Porphyromonas gingivalis To be Published 0 0 0 0
2NNN Crystal structure of probable transcriptional regulator from Pseudomonas aeruginosa 2006-10-24 2006-11-21 Chang, C.,Evdokimova, E.,Altamentova, S.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of probable transcriptional regulator from Pseudomonas aeruginosa To be Published 0 0 0 0
2NT8 17121823 ATP bound at the active site of a PduO type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri 2006-11-07 2006-11-21 St Maurice, M.,Mera, P.E.,Taranto, M.P.,Sesma, F.,Escalante-Semerena, J.C.,Rayment, I. Structural characterization of the active site of the PduO-type ATP:Co(I)rrinoid adenosyltransferase from Lactobacillus reuteri. J.Biol.Chem. 2007 282 2596 2605
2NVW 17121853 Crystal sctucture of transcriptional regulator Gal80p from kluyveromymes lactis 2006-11-13 2006-11-21 Thoden, J.B.,Sellick, C.A.,Reece, R.J.,Holden, H.M. Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p. J.Biol.Chem. 2007 282 1534 1538
2NP5 Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. 2006-10-26 2006-11-28 Chruszcz, M.,Evdokimova, E.,Kagan, O.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Minor, W.,Midwest Center for Structural Genomics (MCSG) Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. TO BE PUBLISHED 0 0 0 0
2NPN Crystal structure of putative cobalamin synthesis related protein (CobF) from Corynebacterium diphtheriae 2006-10-27 2006-11-28 Nocek, B.,Zhou, M.,Clancy, S.,Joachimiak, A. Crystal structure of cobalamin synthesis related protein (CobF) from Corynebacterium diphtheriae To be Published 0 0 0 0
2NQW Structure of the transporter associated domain from PG_0272, a CBS domain protein from Porphyromonas gingivalis 2006-10-31 2006-11-28 Cuff, M.E.,Volkart, L.,Abdullah, J.,Joachimiak, A. Structure of the transporter associated domain from PG_0272, a CBS domain protein from Porphyromonas gingivalis. TO BE PUBLISHED 0 0 0 0
2IOI 17139084 Crystal structure of the mouse p53 core domain at 1.55 A 2006-10-10 2006-12-05 Ho, W.C.,Luo, C.,Zhao, K.,Chai, X.,Fitzgerald, M.X.,Marmorstein, R. High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D 2006 62 1484 1493
2NRK Crystal structure of conserved protein GrpB from Enterococcus faecalis 2006-11-02 2006-12-05 Cuff, M.E.,Mulligan, R.,Bargassa, M.,Joachimiak, A. The structure of conserved protein GrpB from Enterococcus faecalis TO BE PUBLISHED 0 0 0 0
2NS0 Crystal structure of protein RHA04536 from Rhodococcus sp 2006-11-02 2006-12-05 Chang, C.,Skarina, T.,Onopriyenko, O.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of protein RHA04536 from Rhodococcus sp To be Published 0 0 0 0
2F68 16362049 Crystal structure of collagen adhesin (CNA) from S. aureus 2005-11-28 2006-12-12 Zong, Y.,Xu, Y.,Liang, X.,Keene, D.R.,Hook, A.,Gurusiddappa, S.,Hook, M.,Narayana, S.V. A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen. Embo J. 2005 24 4224 4236
2F8D 17565172 BenM effector-Binding domain crystallized from high pH conditions 2005-12-02 2006-12-12 Ezezika, O.C.,Haddad, S.,Neidle, E.L.,Momany, C. Oligomerization of BenM, a LysR-type transcriptional regulator: structural basis for the aggregation of proteins in this family. Acta Crystallogr.,Sect.F 2007 63 361 368
2HHQ 17179038 O6-methyl-guanine:T pair in the polymerase-10 basepair position 2006-06-28 2006-12-12 Warren, J.J.,Forsberg, L.J.,Beese, L.S. The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa 2006 103 19701 19706
2HHV 17179038 T:O6-methyl-guanine in the polymerase-2 basepair position 2006-06-28 2006-12-12 Warren, J.J.,Forsberg, L.J.,Beese, L.S. The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa 2006 103 19701 19706
2NWH Carbohydrate kinase from Agrobacterium tumefaciens 2006-11-14 2006-12-12 Osipiuk, J.,Xu, X.,Gu, J.,Savchenko, A.,Edwards, A.,Joachimiak, A. X-ray crystal structure of carbohydrate kinase from Agrobacterium tumefaciens To be Published 0 0 0 0
2F97 17565172 Effector Binding Domain of BenM (crystals generated from high pH conditions) 2005-12-05 2006-12-19 Ezezika, O.C.,Haddad, S.,Neidle, E.L.,Momany, C. Oligomerization of BenM, a LysR-type transcriptional regulator: structural basis for the aggregation of proteins in this family. Acta Crystallogr.,Sect.F 2007 63 361 368
2I48 17121816 Crystal structure of Bicarbonate Transport Protein CmpA from Synechocystis sp. PCC 6803 in complex with carbonic acid 2006-08-21 2006-12-19 Koropatkin, N.M.,Koppenaal, D.W.,Pakrasi, H.B.,Smith, T.J. The Structure of a Cyanobacterial Bicarbonate Transport Protein, CmpA. J.Biol.Chem. 2007 282 2606 2614
2NZC The structure of uncharacterized protein TM1266 from Thermotoga maritima. 2006-11-22 2006-12-19 Cuff, M.E.,Evdokimova, E.,Kudritska, M.,Edwards, A.,Joachimiak, A.,Savchenko, A. The structure of uncharacterized protein TM1266 from Thermotoga maritima. TO BE PUBLISHED 0 0 0 0
2FHT 17243149 Crystal Structure of Viral Macrophage Inflammatory Protein-II 2005-12-27 2006-12-26 Li, Y.,Liu, D.,Cao, R.,Kumar, S.,Dong, C.,An, J.,Wilson, S.R.,Gao, Y.G.,Huang, Z. Crystal structure of chemically synthesized vMIP-II. Proteins 2007 67 243 246
2I7N 17631502 Crystal structure of human PANK1 alpha: the catalytic core domain in complex with AcCoA 2006-08-31 2006-12-26 Hong, B.S.,Senisterra, G.,Rabeh, W.M.,Vedadi, M.,Leonardi, R.,Zhang, Y.M.,Rock, C.O.,Jackowski, S.,Park, H.W. Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. J.Biol.Chem. 2007 282 27984 27993
2I7P 17631502 Crystal structure of human PANK3 in complex with AcCoA 2006-08-31 2006-12-26 Hong, B.S.,Senisterra, G.,Rabeh, W.M.,Vedadi, M.,Leonardi, R.,Zhang, Y.M.,Rock, C.O.,Jackowski, S.,Park, H.W. Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. J.Biol.Chem. 2007 282 27984 27993
2O0Y Crystal structure of putative transcriptional regulator RHA1_ro06953 (IclR-family) from Rhodococcus sp. 2006-11-28 2006-12-26 Chruszcz, M.,Wang, S.,Skarina, T.,Onopriyenko, O.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Minor, W. Crystal Structure of Putative Transcriptional Regul 2 Rha1_Ro06953(Iclr-Family) from Rhodococcus Sp. To be Published 0 0 0 0
2O6D 17192261 Structure of native rTp34 from Treponema pallidum 2006-12-07 2006-12-26 Deka, R.K.,Brautigam, C.A.,Tomson, F.L.,Lumpkins, S.B.,Tomchick, D.R.,Machius, M.,Norgard, M.V. Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin. J.Biol.Chem. 2007 282 5944 5958
2O6E 17192261 Structure of native rTp34 from Treponema pallidum from zinc-soaked crystals 2006-12-07 2006-12-26 Deka, R.K.,Brautigam, C.A.,Tomson, F.L.,Lumpkins, S.B.,Tomchick, D.R.,Machius, M.,Norgard, M.V. Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin. J.Biol.Chem. 2007 282 5944 5958
2O6F 17192261 Structure of metal- free rTp34 from Treponema pallidum 2006-12-07 2006-12-26 Deka, R.K.,Brautigam, C.A.,Tomson, F.L.,Lumpkins, S.B.,Tomchick, D.R.,Machius, M.,Norgard, M.V. Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin. J.Biol.Chem. 2007 282 5944 5958
2O35 Protein of Unknown Function (DUF1244) from Sinorhizobium meliloti 2006-11-30 2007-01-02 Kim, Y.,Evdokimova, E.,Kudritska, M.,Edwards, A.,Savchenko, A.,Joachimiak, A. The Crystal Structure of Protein of Unknown Function (DUF1244) from Sinorhizobium meliloti To be Published 0 0 0 0
2O38 Putative XRE Family Transcriptional Regulator 2006-11-30 2007-01-02 Kim, Y.,Evdokimova, E.,Kagan, O.,Edwards, A.,Savchenko, A.,Joachimiak, A. The Crystal Structure of Putative XRE Family Transcriptional Regulator To be Published 0 0 0 0
2O3F Structural Genomics, the crystal structure of the N-terminal domain of the putative transcriptional regulator ybbH from Bacillus subtilis subsp. subtilis str. 168. 2006-12-01 2007-01-02 Tan, K.,Bigelow, L.,Abdullah, J.,Joachimiak, A. The crystal structure of the N-terminal domain of the putative transcriptional regulator ybbH from Bacillus subtilis subsp. subtilis str. 168. To be Published 0 0 0 0
2O3G Structural Genomics, the crystal structure of a conserved putative domain from Neisseria meningitidis MC58 2006-12-01 2007-01-02 Tan, K.,Volkart, L.,Gu, M.,Joachimiak, A. The crystal structure of a conserved putative domain from Neisseria meningitidis MC58 To be Published 0 0 0 0
2NYD 17187687 Crystal structure of Staphylococcus aureus hypothetical protein SA1388 2006-11-20 2007-01-09 Singh Saikatendu, K.,Zhang, X.,Kinch, L.,Leybourne, M.,Grishin, N.V.,Zhang, H. Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center. Bmc Struct.Biol. 2006 6 27 27
2O5H Uncharacterized Protein Conserved in Bacteria, COG3792 from Neisseria meningitidis 2006-12-06 2007-01-09 Kim, Y.,Li, H.,Gu, M.,Bargassa, M.,Joachimiak, A. Uncharacterized Protein Conserved in Bacteria, COG3792 from Neisseria meningitidis To be Published 0 0 0 0
2OB5 Crystal structure of protein Atu2016, putative sugar binding protein 2006-12-18 2007-01-16 Chang, C.,Xu, X.,Gu, J.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of protein Atu2016, putative sugar binding protein To be Published 0 0 0 0
2OFY Crystal structure of putative XRE-family transcriptional regulator from Rhodococcus sp. 2007-01-04 2007-01-16 Shumilin, I.A.,Skarina, T.,Onopriyenko, O.,Yim, V.,Chruszcz, M.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Minor, W. Crystal structure of putative XRE-family transcriptional regulator from Rhodococcus sp. To be Published 0 0 0 0
2FN7 Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 2006-01-10 2007-01-23 Senkovich, O.A.,Chattopadhyay, D. Structure of cryptosporidium parvum lactate dehydrogenase in complex with substrates and cofactors To be Published 0 0 0 0
2OCH J-domain of dnj-12 from Caenorhabditis elegans 2006-12-20 2007-01-23 Osipiuk, J.,Maltseva, N.,Gu, M.,Voisine, C.,Morimoto, R.I.,Joachimiak, A. X-ray crystal structure of J-domain of dnj-12 from Caenorhabditis elegans. To be Published 0 0 0 0
2OER Probable Transcriptional Regulator from Pseudomonas aeruginosa 2006-12-31 2007-01-30 Kim, Y.,Skarina, T.,Kagan, O.,Edwards, A.,Savchenko, A.,Joachimiak, A. Crystal Structure of the Probable Transcriptional Regulator from Pseudomonas aeruginosa To be Published 0 0 0 0
2OMO Putative antibiotic biosynthesis monooxygenase from Nitrosomonas europaea 2007-01-22 2007-01-30 Osipiuk, J.,Evdokimova, E.,Kagan, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. X-ray structure of putative antibiotic biosynthesis monooxygenase from Nitrosomonas europaea. To be Published 0 0 0 0
2CD8 16825192 Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1) 2006-01-20 2007-02-20 Sherman, D.H.,Li, S.,Yermalitskaya, L.V.,Kim, Y.,Smith, J.A.,Waterman, M.R.,Podust, L.M. The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem. 2006 281 26289 0
2OIW The structure of a predicted thioesterase from Bacillus stearothermophilus 2007-01-11 2007-02-20 Cuff, M.E.,Li, H.,Moy, S.,Joachimiak, A. The structure of a predicted thioesterase from Bacillus stearothermophilus TO BE PUBLISHED 0 0 0 0
2J9F 17329260 Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase E1b 2006-11-07 2007-02-27 Li, J.,Machius, M.,Chuang, J.L.,Wynn, R.M.,Chuang, D.T. The Two Active Sites in Human Branched-Chain Alpha- Keto Acid Dehydrogenase Operate Independently without an Obligatory Alternating-Site Mechanism. J.Biol.Chem. 2007 282 11904 0
2OJH The structure of putative TolB from Agrobacterium tumefaciens 2007-01-12 2007-02-27 Cuff, M.E.,Xu, X.,Gu, J.,Edwards, A.,Savchenko, A.,Joachimiak, A. The structure of putative TolB from Agrobacterium tumefaciens TO BE PUBLISHED 0 0 0 0
2OP6 Peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans 2007-01-26 2007-02-27 Osipiuk, J.,Duggan, E.,Gu, M.,Voisine, C.,Morimoto, R.I.,Joachimiak, A. X-ray structure of peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans To be Published 0 0 0 0
2OQG ArsR-like Transcriptional Regulator from Rhodococcus sp. RHA1 2007-01-31 2007-03-06 Kim, Y.,Xu, X.,Zheng, H.,Edwards, A.,Savchenko, A.,Joachimiak, A. Crystal Structure of the ArsR-like Transcriptional Regulator from Rhodococcus sp. RHA1 To be Published 0 0 0 0
2OR0 Structural Genomics, the crystal structure of a putative hydroxylase from Rhodococcus sp. RHA1 2007-02-01 2007-03-06 Tan, K.,Skarina, T.,Kagen, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of a putative hydroxylase from Rhodococcus sp. RHA1 To be Published 0 0 0 0
2NV9 17305368 The X-ray Crystal Structure of the Paramecium bursaria Chlorella virus arginine decarboxylase 2006-11-11 2007-03-20 Shah, R.,Akella, R.,Goldsmith, E.J.,Phillips, M.A. X-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity. Biochemistry 2007 46 2831 2841
2DG2 18202122 Crystal Structure of Mouse Apolipoprotein A-I Binding Protein 2006-03-08 2007-03-27 Jha, K.N.,Shumilin, I.A.,Digilio, L.C.,Chertihin, O.,Zheng, H.,Schmitz, G.,Visconti, P.E.,Flickinger, C.J.,Minor, W.,Herr, J.C. Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation. Endocrinology 2008 149 2108 2120
2H0R 17382284 Structure of the Yeast Nicotinamidase Pnc1p 2006-05-15 2007-03-27 Hu, G.,Taylor, A.B.,McAlister-Henn, L.,Hart, P.J. Crystal structure of the yeast nicotinamidase Pnc1p. Arch.Biochem.Biophys. 2007 461 66 75
2H0R 17382284 Structure of the Yeast Nicotinamidase Pnc1p 2006-05-15 2007-03-27 Hu, G.,Taylor, A.B.,McAlister-Henn, L.,Hart, P.J. Crystal structure of the yeast nicotinamidase Pnc1p. Arch.Biochem.Biophys. 2007 461 66 75
2O0A 17382884 The structure of the C-terminal domain of Vik1 has a motor domain fold but lacks a nucleotide-binding site. 2006-11-27 2007-03-27 Allingham, J.S.,Sproul, L.R.,Rayment, I.,Gilbert, S.P. Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site. Cell(Cambridge,Mass.) 2007 128 1161 1172
2GL2 17142900 Crystal structure of the tetra mutant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA 2006-04-04 2007-04-10 Nithianantham, S.,Xu, M.,Wu, N.,Han, Y.W.,Shoham, M. Crystallization and preliminary X-ray data of the FadA adhesin from Fusobacterium nucleatum. Acta Crystallogr.,Sect.F 2006 62 1215 1217
2P3H Crystal structure of the CorC_HlyC domain of a putative Corynebacterium glutamicum hemolysin 2007-03-08 2007-04-10 Cuff, M.E.,Volkart, L.,Gu, M.,Joachimiak, A. Structure of the CorC_HlyC domain of a putative Corynebacterium glutamicum hemolysin. TO BE PUBLISHED 0 0 0 0
2PA7 17459872 Structure of Wild-Type dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus in complex with TDP 2007-03-27 2007-04-24 Davis, M.L.,Thoden, J.B.,Holden, H.M. The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase. J.Biol.Chem. 2007 282 19227 19236
2PDO Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri 2007-04-01 2007-04-24 Kim, Y.,Li, H.,Holzle, D.,Joachimiak, A. Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri To be Published 0 0 0 0
2OV5 17441734 Crystal structure of the KPC-2 carbapenemase 2007-02-13 2007-05-01 Ke, W.,Bethel, C.R.,Thomson, J.M.,Bonomo, R.A.,Akker, F. Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A beta-Lactamases. Biochemistry 2007 46 5732 5740
2GW3 17692334 Crystal structure of stony coral fluorescent protein Kaede, green form 2006-05-03 2007-05-08 Hayashi, I.,Mizuno, H.,Tong, K.I.,Furuta, T.,Tanaka, F.,Yoshimura, M.,Miyawaki, A.,Ikura, M. Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede. J.Mol.Biol. 2007 372 918 926
2CMN 16813836 A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor 2006-05-11 2007-05-15 Gilles-Gonzalez, M.-A.,Caceres, A.I.,Silva Sousa, E.H.,Tomchick, D.R.,Brautigam, C.A.,Gonzalez, C.,Machius, M. A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium Japonicum Fixl Oxygen Sensor J.Mol.Biol. 2006 360 80 0
2PJS Crystal structure of Atu1953, protein of unknown function 2007-04-16 2007-05-15 Chang, C.,Skarina, T.,Onopriyenko, O.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein Atu1953, protein of unknown function To be Published 0 0 0 0
2OVE 17452033 Crystal Structure of Recombinant Human Complement Protein C8gamma 2007-02-13 2007-05-22 Chiswell, B.,Lovelace, L.L.,Brannen, C.,Ortlund, E.A.,Lebioda, L.,Sodetz, J.M. Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family Biochim.Biophys.Acta 2007 1774 637 644
2OZL 17474719 Human pyruvate dehydrogenase S264E variant 2007-02-26 2007-05-22 Seifert, F.,Ciszak, E.M.,Korotchkina, L.G.,Golbik, R.,Spinka, M.,Dominiak, P.M.,Sidhu, S.,Brauer, J.,Patel, M.S.,Tittmann, K. Phosphorylation of Serine 264 Impedes Active Site Accessibility in the E1 Component of the Human Pyruvate Dehydrogenase Multienzyme Complex Biochemistry 2007 46 6277 6287
2PLI Crystal structure of putative Mg2+ and Co2+ transporter(CorC)associated region from Neisseria meningitidis MC58 2007-04-19 2007-05-22 Nocek, B.,Duggan, E.,Gu, M.,Joachimiak, A. Structure of putative Mg2+ and Co2+ transporter(CorC)associated region from Neisseria meningitidis MC58. To be Published 0 0 0 0
2OIV 17204475 Structural Analysis of Xanthomonas XopD Provides Insights Into Substrate Specificity of Ubiquitin-like Protein Proteases 2007-01-11 2007-05-29 Chosed, R.,Tomchick, D.R.,Brautigam, C.A.,Mukherjee, S.,Negi, V.S.,Machius, M.,Orth, K. Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases. J.Biol.Chem. 2007 282 6773 6782
2OIX 17204475 Xanthomonas XopD C470A Mutant 2007-01-11 2007-05-29 Chosed, R.,Tomchick, D.R.,Brautigam, C.A.,Mukherjee, S.,Negi, V.S.,Machius, M.,Orth, K. Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases. J.Biol.Chem. 2007 282 6773 6782
2UXN 17529991 Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation 2007-03-28 2007-05-29 Yang, M.,Culhane, J.C.,Szewczuk, L.M.,Gocke, C.B.,Brautigam, C.A.,Tomchick, D.R.,Machius, M.,Cole, P.A.,Yu, H. Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation. Nat.Struct.Mol.Biol. 2007 14 535 0
2PQQ Structural Genomics, the crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) 2007-05-02 2007-06-05 Tan, K.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. The crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) To be Published 0 0 0 0
2OQZ 17545669 The crystal structure of sortase B from B.anthracis in complex with AAEK2 2007-02-01 2007-06-19 Maresso, A.W.,Wu, R.,Kern, J.W.,Zhang, R.,Janik, D.,Missiakas, D.M.,Duban, M.E.,Joachimiak, A.,Schneewind, O. Activation of inhibitors by sortase triggers irreversible modification of the active site. J.Biol.Chem. 2007 282 23129 23139
2P63 17574027 Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination 2007-03-16 2007-06-19 Tang, X.,Orlicky, S.,Lin, Z.,Willems, A.,Neculai, D.,Ceccarelli, D.,Mercurio, F.,Shilton, B.H.,Sicheri, F.,Tyers, M. Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination. Cell(Cambridge,Mass.) 2007 129 1165 1176
2H98 Crystal structure of the effector binding domain of a CatM variant, CatM(V158M) 2006-06-09 2007-06-26 Ezezika, O.C.,Neidle, E.L.,Momany, C. Structural basis for the altered regulatory roles of three LysR-type transcritional variants of CatM and BenM: CatM(V158M), CatM(R156H) and BenM(R156H/T157S) To be Published 0 0 0 0
2Q6J 17584613 Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand 2007-06-05 2007-06-26 Zhou, H.-B.,Nettles, K.W.,Bruning, J.B.,Kim, Y.,Joachimiak, A.,Sharma, S.,Carlson, K.E.,Stossi, F.,Katzenellenbogen, B.S.,Greene, G.L.,Katzenellenbogen, J.A. Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Chem.Biol. 2007 14 659 669
2I5R 17705269 Structure of small Toprim domain-containing protein from B. stearothermophilus in complex with Mg2+ 2006-08-25 2007-07-03 Rezacova, P.,Borek, D.,Moy, S.F.,Joachimiak, A.,Otwinowski, Z. Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus. Proteins 2007 70 311 319
2Q24 21625866 Crystal structure of TetR transcriptional regulator SCO0520 from Streptomyces coelicolor 2007-05-25 2007-07-03 Filippova, E.V.,Chruszcz, M.,Cymborowski, M.,Gu, J.,Savchenko, A.,Edwards, A.,Minor, W. Crystal structure of a putative transcriptional regulator SCO0520 from Streptomyces coelicolor A3(2) reveals an unusual dimer among TetR family proteins. J.Struct.Funct.Genom. 2011 12 149 157
2I5Z 17335845 The crystal structure of OspA mutant 2006-08-26 2007-07-10 Yan, S.,Gawlak, G.,Makabe, K.,Tereshko, V.,Koide, A.,Koide, S. Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet. J.Mol.Biol. 2007 368 230 243
2PLJ 17626020 Crystal structure of lysine/ornithine decarboxylase complexed with putrescine from Vibrio vulnificus 2007-04-19 2007-07-10 Lee, J.,Michael, A.J.,Martynowski, D.,Goldsmith, E.J.,Phillips, M.A. Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases. J.Biol.Chem. 2007 282 27115 27125
2PLK 17626020 Crystal structure of lysine/ornithine decarboxylase complexed with cadaverine from Vibrio vulnificus 2007-04-19 2007-07-10 Lee, J.,Michael, A.J.,Martynowski, D.,Goldsmith, E.J.,Phillips, M.A. Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases. J.Biol.Chem. 2007 282 27115 27125
2Q0R 17599353 Structure of Pectenotoxin-2 Bound to Actin 2007-05-22 2007-07-17 Allingham, J.S.,Miles, C.O.,Rayment, I. A structural basis for regulation of actin polymerization by pectenotoxins. J.Mol.Biol. 2007 371 959 970
2Q0U 17599353 Structure of Pectenotoxin-2 and Latrunculin B Bound to Actin 2007-05-22 2007-07-17 Allingham, J.S.,Miles, C.O.,Rayment, I. A structural basis for regulation of actin polymerization by pectenotoxins. J.Mol.Biol. 2007 371 959 970
2QHQ Crystal structure of unknown function protein VPA0580 2007-07-02 2007-07-17 Chang, C.,Kim, Y.,Volkart, L.,Abdullah, J.,Joachimiak, A. Crystal structure of unknown function protein VPA0580. To be Published 0 0 0 0
2PN5 17606907 Crystal Structure of TEP1r 2007-04-23 2007-07-24 Baxter, R.H.G.,Chang, C.I.,Chelliah, Y.,Blandin, S.,Levashina, E.A.,Deisenhofer, J. Structural basis for conserved complement factor-like function in the antimalarial protein TEP1 Proc.Natl.Acad.Sci.Usa 2007 104 11615 11620
2Q8F 17683942 Structure of pyruvate dehydrogenase kinase isoform 1 2007-06-10 2007-07-24 Kato, M.,Li, J.,Chuang, J.L.,Chuang, D.T. Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure 2007 15 992 1004
2Q8G 17683942 Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 2007-06-10 2007-07-24 Kato, M.,Li, J.,Chuang, J.L.,Chuang, D.T. Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure 2007 15 992 1004
2Q8H 17683942 Structure of pyruvate dehydrogenase kinase isoform 1 in complex with dichloroacetate (DCA) 2007-06-10 2007-07-24 Kato, M.,Li, J.,Chuang, J.L.,Chuang, D.T. Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure 2007 15 992 1004
2Q8I 17683942 Pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug radicicol 2007-06-10 2007-07-24 Kato, M.,Li, J.,Chuang, J.L.,Chuang, D.T. Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure 2007 15 992 1004
2QNG Crystal structure of unknown function protein SAV2460 2007-07-18 2007-07-31 Chang, C.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of SAV2460. To be Published 0 0 0 0
2QLT Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae 2007-07-13 2007-08-07 Tan, K.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p from Saccharomyces cerevisiae. To be Published 0 0 0 0
2QQZ Crystal structure of putative glyoxalase family protein from Bacillus anthracis 2007-07-27 2007-08-14 Kim, Y.,Joachimiak, G.,Wu, R.,Patterson, S.,Gornicki, P.,Joachimiak, A. Crystal Structure of Putative Glyoxalase Family Protein from Bacillus anthracis. To be Published 0 0 0 0
2HQH 17828275 Crystal structure of p150Glued and CLIP-170 2006-07-18 2007-08-21 Hayashi, I.,Plevin, M.J.,Ikura, M. CLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1. Nat.Struct.Mol.Biol. 2007 14 980 981
2ODL 17699157 Crystal structure of the HMW1 secretion domain from Haemophilus influenzae 2006-12-22 2007-08-21 Yeo, H.J.,Yokoyama, T.,Walkiewicz, K.,Kim, Y.,Grass, S.,Geme, J.W. The structure of the Haemophilus influenzae HMW1 pro-piece reveals a structural domain essential for bacterial two-partner secretion. J.Biol.Chem. 2007 282 31076 31084
2PVZ 17567742 Crystal structure of methylaconitate isomerase PrpF from Shewanella oneidensis 2007-05-10 2007-08-21 Garvey, G.S.,Rocco, C.J.,Escalante-Semerena, J.C.,Rayment, I. The three-dimensional crystal structure of the PrpF protein of Shewanella oneidensis complexed with trans-aconitate: insights into its biological function. Protein Sci. 2007 16 1274 1284
2PW0 17567742 crystal structure of trans-aconitate bound to methylaconitate isomerase PrpF from Shewanella oneidensis 2007-05-10 2007-08-21 Garvey, G.S.,Rocco, C.J.,Escalante-Semerena, J.C.,Rayment, I. The three-dimensional crystal structure of the PrpF protein of Shewanella oneidensis complexed with trans-aconitate: insights into its biological function. Protein Sci. 2007 16 1274 1284
2QSW Crystal structure of C-terminal domain of ABC transporter / ATP-binding protein from Enterococcus faecalis 2007-07-31 2007-08-21 Osipiuk, J.,Bigelow, L.,Clancy, S.,Joachimiak, A. X-ray structure of C-terminal domain of ABC transporter / ATP-binding protein from Enterococcus faecalis. To be Published 0 0 0 0
2J9J 17869270 Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365 2006-11-11 2007-08-28 Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol. 2007 373 573 0
2J9K 17869270 Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor MVT-101 2006-11-11 2007-08-28 Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol. 2007 373 573 0
2JE4 17705484 Atomic-resolution crystal structure of chemically-synthesized HIV-1 protease in complex with JG-365 2007-01-15 2007-08-28 Johnson, E.C.B.,Malito, E.,Shen, Y.,Rich, D.,Tang, W.J.,Kent, S.B. Modular Total Chemical Synthesis of a Human Immunodeficiency Virus Type 1 Protease. J.Am.Chem.Soc. 2007 129 11480 0
2Q3X 17630786 The RIM1alpha C2B domain 2007-05-30 2007-08-28 Guan, R.,Dai, H.,Tomchick, D.R.,Dulubova, I.,Machius, M.,Sudhof, T.C.,Rizo, J. Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry 2007 46 8988 8998
2QF7 17717183 Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli 2007-06-27 2007-09-04 St Maurice, M.,Reinhardt, L.,Surinya, K.H.,Attwood, P.V.,Wallace, J.C.,Cleland, W.W.,Rayment, I. Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science 2007 317 1076 1079
2QNJ 17726107 Kinase and Ubiquitin-associated domains of MARK3/Par-1 2007-07-18 2007-09-04 Murphy, J.M.,Korzhnev, D.M.,Ceccarelli, D.F.,Briant, D.J.,Zarrine-Afsar, A.,Sicheri, F.,Kay, L.E.,Pawson, T. Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain Proc.Natl.Acad.Sci.Usa 2007 104 14336 14341
2QRU Crystal structure of an alpha/beta hydrolase superfamily protein from Enterococcus faecalis 2007-07-29 2007-09-11 Cuff, M.E.,Volkart, L.,Moy, S.,Joachimiak, A. Structure of an alpha/beta hydrolase superfamily protein from Enterococcus faecalis. TO BE PUBLISHED 0 0 0 0
2R39 Crystal structure of FixG-related protein from Vibrio parahaemolyticus 2007-08-29 2007-09-11 Chang, C.,Bigelow, L.,Abdullah, J.,Joachimiak, A. Crystal structure of FixG-related protein from Vibrio parahaemolyticus. To be Published 0 0 0 0
2R47 Crystal structure of MTH_862 protein of unknown function from Methanothermobacter thermautotrophicus 2007-08-30 2007-09-11 Osipiuk, J.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of MTH_862 protein of unknown function from Methanothermobacter thermautotrophicus. To be Published 0 0 0 0
2R6H Crystal structure of the domain comprising the NAD binding and the FAD binding regions of the NADH:ubiquinone oxidoreductase, Na translocating, F subunit from Porphyromonas gingivalis 2007-09-05 2007-09-11 Kim, Y.,Mulligan, R.,Moy, S.,Joachimiak, A. Crystal Structure of the Domain Comprising the Regions Binding NAD and FAD from the NADH:Ubiquinone Oxidoreductase, Na Translocating, F Subunit from Porphyromonas gingivalis. To be Published 0 0 0 0
2QOH 17718712 Crystal Structure of Abl kinase bound with PPY-A 2007-07-20 2007-09-18 Zhou, T.,Parillon, L.,Li, F.,Wang, Y.,Keats, J.,Lamore, S.,Xu, Q.,Shakespeare, W.,Dalgarno, D.,Zhu, X. Crystal Structure of the T315I Mutant of Abl Kinase Chem.Biol.Drug Des. 2007 70 171 181
2R4Q The structure of a domain of fruA from Bacillus subtilis 2007-08-31 2007-09-18 Cuff, M.E.,Sather, A.,Nocek, B.,Clancy, S.,Joachimiak, A. The structure of a domain of fruA from Bacillus subtilis. TO BE PUBLISHED 0 0 0 0
2R5F Putative sugar-binding domain of transcriptional regulator DeoR from Pseudomonas syringae pv. tomato 2007-09-03 2007-09-18 Cuff, M.E.,Duggan, E.,Clancy, S.,Joachimiak, A. Putative sugar-binding domain of trancsriptional regulator DeoR from Pseudomonas syringae pv. tomato. TO BE PUBLISHED 0 0 0 0
2R5S The crystal structure of a domain of protein VP0806 (unknown function) from Vibrio parahaemolyticus RIMD 2210633 2007-09-04 2007-09-18 Tan, K.,Wu, R.,Abdullah, J.,Freeman, L.,Joachimiak, A. The crystal structure of a domain of protein VP0806 (unknown function) from Vibrio parahaemolyticus RIMD 2210633. To be Published 0 0 0 0
2R6O 20691189 Crystal structure of putative diguanylate cyclase/phosphodiesterase from Thiobacillus denitrificans 2007-09-06 2007-09-18 Tchigvintsev, A.,Xu, X.,Singer, A.,Chang, C.,Brown, G.,Proudfoot, M.,Cui, H.,Flick, R.,Anderson, W.F.,Joachimiak, A.,Galperin, M.Y.,Savchenko, A.,Yakunin, A.F. Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J.Mol.Biol. 2010 402 524 538
2Z60 17718712 Crystal Structure of the T315I Mutant of Abl kinase bound with PPY-A 2007-07-21 2007-09-18 Zhou, T.,Parillon, L.,Li, F.,Wang, Y.,Keats, J.,Lamore, S.,Xu, Q.,Shakespeare, W.,Dalgarno, D.,Zhu, X. Crystal Structure of the T315I Mutant of Abl Kinase Chem.Biol.Drug Des. 2007 70 171 181
2IQY Rat Phosphatidylethanolamine-Binding Protein 2006-10-14 2007-09-25 Kim, Y.,Joachimiak, G.,Heil, G.L.,Koide, S.,Joachimiak, A. Crystal Structure of Rat Phosphatidylethanolamine-Binding Protein To be Published 0 0 0 0
2R78 Crystal structure of a domain of the sensory box sensor histidine kinase/response regulator from Geobacter sulfurreducens 2007-09-07 2007-09-25 Zhang, R.,Sather, A.,Clancy, S.,Joachimiak, A. The crystal structure of a domain of the sensory box sensor histidine kinase/response regulator from Geobacter sulfurreducens. To be Published 0 0 0 0
2V84 17868688 Crystal Structure of the Tp0655 (TpPotD) Lipoprotein of Treponema pallidum 2007-08-02 2007-09-25 Machius, M.,Brautigam, C.A.,Tomchick, D.R.,Ward, P.,Otwinowski, Z.,Blevins, J.S.,Deka, R.K.,Norgard, M.V. Structural and Biochemical Basis for Polyamine Binding to the Tp0655 Lipoprotein of Treponema Pallidum: Putative Role for Tp0655 (Tppotd) as a Polyamine Receptor. J.Mol.Biol. 2007 373 681 0
2Q67 17878296 Crystal Structure of Nak channel D66A mutant 2007-06-04 2007-10-02 Alam, A.,Shi, N.,Jiang, Y. Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa 2007 104 15334 15339
2Q68 17878296 Crystal Structure of Nak channel D66A, S70E double mutants 2007-06-04 2007-10-02 Alam, A.,Shi, N.,Jiang, Y. Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa 2007 104 15334 15339
2Q6A 17878296 Crystal Structure of Nak channel D66E mutant 2007-06-04 2007-10-02 Alam, A.,Shi, N.,Jiang, Y. Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa 2007 104 15334 15339
2QEB 17928288 Crystal Structure of Anopheles Gambiae D7R4-Histamine Complex 2007-06-25 2007-10-09 Mans, B.J.,Calvo, E.,Ribeiro, J.M.,Andersen, J.F. The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae J.Biol.Chem. 2007 282 36626 36633
2QEO 17928288 Crystal Structure of Anopheles gambiae D7R4-norepinephrine complex 2007-06-26 2007-10-09 Mans, B.J.,Calvo, E.,Ribeiro, J.M.,Andersen, J.F. The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae J.Biol.Chem. 2007 282 36626 36633
2QKV 17923089 Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD 2007-07-11 2007-11-06 Mishra, P.,Socolich, M.,Wall, M.A.,Graves, J.,Wang, Z.,Ranganathan, R. Dynamic Scaffolding in a G Protein-Coupled Signaling System. Cell(Cambridge,Mass.) 2007 131 80 92
2RBC Crystal structure of a putative ribokinase from Agrobacterium tumefaciens 2007-09-18 2007-11-13 Cuff, M.E.,Xu, X.,Zheng, H.,Edwards, A.M.,Savchenko, A.,Joachimiak, A. Structure of a putative ribokinase from Agrobacterium tumefaciens. TO BE PUBLISHED 0 0 0 0
2RC4 17925393 Crystal Structure of the HAT domain of the human MOZ protein 2007-09-19 2007-11-13 Holbert, M.A.,Sikorski, T.,Carten, J.,Snowflack, D.,Hodawadekar, S.,Marmorstein, R. The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. J.Biol.Chem. 2007 282 36603 36613
2RDP The structure of a MarR family protein from Bacillus stearothermophilus 2007-09-24 2007-11-13 Cuff, M.E.,Duggan, E.,Dementieva, I.,Moy, S.,Joachimiak, A. The structure of a MarR family protein from Bacillus stearothermophilus. TO BE PUBLISHED 0 0 0 0
2R8S 18162543 High resolution structure of a specific synthetic FAB bound to P4-P6 RNA ribozyme domain 2007-09-11 2007-12-04 Ye, J.D.,Tereshko, V.,Frederiksen, J.K.,Koide, A.,Fellouse, F.A.,Sidhu, S.S.,Koide, S.,Kossiakoff, A.A.,Piccirilli, J.A. Synthetic antibodies for specific recognition and crystallization of structured RNA Proc.Natl.Acad.Sci.Usa 2008 105 82 87
2O6U 19898606 Crystal structure of the PA5185 protein from Pseudomonas Aeruginosa strain PAO1- new crystal form. 2006-12-08 2007-12-11 Chruszcz, M.,Zimmerman, M.D.,Wang, S.,Koclega, K.D.,Zheng, H.,Evdokimova, E.,Kudritska, M.,Cymborowski, M.,Savchenko, A.,Edwards, A.,Minor, W. Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1. Cryst.Growth Des. 2008 8 4054 4061
2QQS 18084306 JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide 2007-07-26 2007-12-11 Lee, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol. 2008 15 109 111
2RKT 17923480 Crystal Structure of apo F. graminearum TRI101 2007-10-17 2007-12-11 Garvey, G.S.,McCormick, S.P.,Rayment, I. Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem. 2008 283 1660 1669
2RKV 17923480 Crystal Structure of F. graminearum TRI101 complexed with Coenzyme A and T-2 mycotoxin 2007-10-17 2007-12-11 Garvey, G.S.,McCormick, S.P.,Rayment, I. Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem. 2008 283 1660 1669
2ZBA 17923480 Crystal Structure of F. sporotrichioides TRI101 complexed with Coenzyme A and T-2 2007-10-18 2007-12-11 Garvey, G.S.,McCormick, S.P.,Rayment, I. Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem. 2008 283 1660 1669
3B2S 17923480 Crystal Structure of F. graminearum TRI101 complexed with Coenzyme A and Deoxynivalenol 2007-10-19 2007-12-11 Garvey, G.S.,McCormick, S.P.,Rayment, I. Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem. 2008 283 1660 1669
3B30 17923480 Crystal Structure of F. graminearum TRI101 complexed with Ethyl Coenzyme A 2007-10-19 2007-12-11 Garvey, G.S.,McCormick, S.P.,Rayment, I. Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem. 2008 283 1660 1669
3BJD Crystal structure of putative 3-oxoacyl-(acyl-carrier-protein) synthase from Pseudomonas aeruginosa 2007-12-03 2007-12-11 Osipiuk, J.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal structure of putative 3-oxoacyl-(acyl-carrier-protein) synthase from Pseudomonas aeruginosa. To be Published 0 0 0 0
2R9I Crystal structure of putative phage capsid protein domain from Corynebacterium diphtheriae 2007-09-12 2007-12-18 Wu, R.,Abdullah, J.,Joachimiak, A. The crystal structure of putative phage capsid protein domain from Corynebacterium diphtheriae. To be Published 0 0 0 0
3BJ6 Crystal structure of MarR family transcription regulator SP03579 2007-12-03 2007-12-18 Kim, Y.,Volkart, L.,Keigher, L.,Joachimiak, A. Crystal Structure of MarR family Transcription Regulator SP03579. To be Published 0 0 0 0
3BJZ 18056714 Crystal structure of Pseudomonas aeruginosa phosphoheptose isomerase 2007-12-05 2007-12-18 Taylor, P.L.,Blakely, K.M.,de Leon, G.P.,Walker, J.R.,McArthur, F.,Evdokimova, E.,Zhang, K.,Valvano, M.A.,Wright, G.D.,Junop, M.S. Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants. J.Biol.Chem. 2008 283 2835 2845
2O8N 18202122 Crystal Structure of Mouse Apolipoprotein A-I Binding Protein 2006-12-12 2007-12-25 Jha, K.N.,Shumilin, I.A.,Digilio, L.C.,Chertihin, O.,Zheng, H.,Schmitz, G.,Visconti, P.E.,Flickinger, C.J.,Minor, W.,Herr, J.C. Biochemical and Structural Characterization of Apolipoprotein A-I Binding Protein, a Novel Phosphoprotein with a Potential Role in Sperm Capacitation. Endocrinology 2008 149 2108 2120
3BP1 20875425 Crystal structure of putative 7-cyano-7-deazaguanine reductase QueF from Vibrio cholerae O1 biovar eltor 2007-12-18 2008-01-08 Kim, Y.,Zhou, M.,Moy, S.,Morales, J.,Cunningham, M.A.,Joachimiak, A. High-resolution structure of the nitrile reductase QueF combined with molecular simulations provide insight into enzyme mechanism. J.Mol.Biol. 2010 404 127 137
3BQW Crystal structure of the putative capsid protein of prophage (E.coli CFT073) 2007-12-20 2008-01-08 Zhang, R.,Hatzos, C.,Abdullah, J.,Joachimiak, A. The crystal structure of the putative capsid protein of prophage (E.coli CFT073). To be Published 0 0 0 0
3BQY Crystal structure of a possible TetR family transcriptional regulator from Streptomyces coelicolor A3(2). 2007-12-20 2008-01-15 Cuff, M.E.,Skarina, T.,Kagan, O.,Edwards, A.M.,Savchenko, A.,Joachimiak, A. Structure of a possible TetR family transcriptional regulator from Streptomyces coelicolor A3(2). TO BE PUBLISHED 0 0 0 0
2RIO 18191223 Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation of non-conventional splicing 2007-10-12 2008-01-29 Lee, K.P.,Dey, M.,Neculai, D.,Cao, C.,Dever, T.E.,Sicheri, F. Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell(Cambridge,Mass.) 2008 132 89 100
3BV8 Crystal structure of the N-terminal domain of tetrahydrodipicolinate acetyltransferase from Staphylococcus aureus 2008-01-04 2008-02-05 Cuff, M.E.,Duggan, E.,Clancy, S.,Joachimiak, A. Structure of the N-terminal domain of tetrahydrodipicolinate acetyltransferase from Staphylococcus aureus. TO BE PUBLISHED 0 0 0 0
3C2Q Crystal structure of conserved putative LOR/SDH protein from Methanococcus maripaludis S2 2008-01-25 2008-02-05 Duke, N.,Gu, M.,Mulligan, R.,Conrad, B.,Joachimiak, A. Crystal structure of conserved putative LOR/SDH protein from Methanococcus maripaludis S2 To be Published 0 0 0 0
2EHZ Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 4-methylcatechol 2007-03-10 2008-02-19 Neau, D.B.,Kelker, M.S.,Maaroufi, H.,Colbert, C.L.,Eltis, L.D.,Bolin, J.T. Structural explanation for success and failure in the enzymatic ring-cleavage of 3,4 dihydroxybiphenyl and related PCB metabolites To be Published 0 0 0 0
2EI0 Anaerobic Crystal Structure Analysis of 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. strain C18 complexed with 3,4-dihydroxybiphenyl 2007-03-10 2008-02-19 Neau, D.B.,Kelker, M.S.,Maaroufi, H.,Colbert, C.L.,Eltis, L.D.,Bolin, J.T. Structural explanation for success and failure in the enzymatic ring-cleavage of 3,4 dihydroxybiphenyl and related PCB metabolites To be Published 0 0 0 0
2EI1 Anaerobic Crystal Structure Analysis of the 1,2-dihydroxynaphthalene dioxygeanse of Pseudomonas sp. strain C18 complexes to 1,2-dihydroxynaphthalene 2007-03-10 2008-02-19 Neau, D.B.,Kelker, M.S.,Maaroufi, H.,Colbert, C.L.,Eltis, L.D.,Bolin, J.T. Structural explanation for success and failure in the enzymatic ring-cleavage of 3,4 dihydroxybiphenyl and related PCB metabolites. To be Published 0 0 0 0
2EI2 Crystal Structure Analysis of the 1,2-dihydroxynaphthalene dioxygenase from Pseudomonas sp. stain C18 2007-03-10 2008-02-19 Neau, D.B.,Kelker, M.S.,Maaroufi, H.,Colbert, C.L.,Eltis, L.D.,Bolin, J.T. Structural explanation for success and failure in the enzymatic ring-cleavage of 3,4 dihydroxybiphenyl and related PCB metabolites To be Published 0 0 0 0
3C8G 19840941 Crystal structure of a possible transciptional regulator YggD from Shigella flexneri 2a str. 2457T 2008-02-12 2008-02-19 Tan, K.,Clancy, S.,Borovilos, M.,Zhou, M.,Horer, S.,Moy, S.,Volkart, L.L.,Sassoon, J.,Baumann, U.,Joachimiak, A. The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J.Biol.Chem. 2009 284 36670 36679
3BIK 18287011 Crystal Structure of the PD-1/PD-L1 Complex 2007-11-30 2008-02-26 Lin, D.Y.,Tanaka, Y.,Iwasaki, M.,Gittis, A.G.,Su, H.P.,Mikami, B.,Okazaki, T.,Honjo, T.,Minato, N.,Garboczi, D.N. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc.Natl.Acad.Sci.Usa 2008 105 3011 3016
3BIS 18287011 Crystal Structure of the PD-L1 2007-11-30 2008-02-26 Lin, D.Y.,Tanaka, Y.,Iwasaki, M.,Gittis, A.G.,Su, H.P.,Mikami, B.,Okazaki, T.,Honjo, T.,Minato, N.,Garboczi, D.N. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc.Natl.Acad.Sci.Usa 2008 105 3011 3016
2QJO 18275811 crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase (NadM) complexed with ADPRP and NAD from Synechocystis sp. 2007-07-08 2008-03-11 Huang, N.,Sorci, L.,Zhang, X.,Brautigam, C.A.,Li, X.,Raffaelli, N.,Magni, G.,Grishin, N.V.,Osterman, A.L.,Zhang, H. Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism. Structure 2008 16 196 209
2QGT 18344977 Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound 2007-06-29 2008-03-18 Nettles, K.W.,Bruning, J.B.,Gil, G.,Nowak, J.,Sharma, S.K.,Hahm, J.B.,Kulp, K.,Hochberg, R.B.,Zhou, H.,Katzenellenbogen, J.A.,Katzenellenbogen, B.S.,Kim, Y.,Joachmiak, A.,Greene, G.L. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol. 2008 4 241 247
2QGW 18344977 Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with a Chloro-Indazole Compound 2007-06-29 2008-03-18 Nettles, K.W.,Bruning, J.B.,Gil, G.,Nowak, J.,Sharma, S.K.,Hahm, J.B.,Kulp, K.,Hochberg, R.B.,Zhou, H.,Katzenellenbogen, J.A.,Katzenellenbogen, B.S.,Kim, Y.,Joachmiak, A.,Greene, G.L. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol. 2008 4 241 247
3CDH Crystal structure of the MarR family transcriptional regulator SPO1453 from Silicibacter pomeroyi DSS-3 2008-02-26 2008-03-18 Kim, Y.,Volkart, L.,Keigher, L.,Joachimiak, A. Crystal structure of the MarR family transcriptional regulator SPO1453 from Silicibacter pomeroyi. To be Published 0 0 0 0
3CK6 19653298 Crystal structure of ZntB cytoplasmic domain from Vibrio parahaemolyticus RIMD 2210633 2008-03-14 2008-03-25 Tan, K.,Sather, A.,Robertson, J.L.,Moy, S.,Roux, B.,Joachimiak, A. Structure and electrostatic property of cytoplasmic domain of ZntB transporter. Protein Sci. 2009 18 2043 2052
2R1D 18334217 Crystal structure of rat neurexin 1beta in the Ca2+ containing form 2007-08-22 2008-04-01 Shen, K.C.,Kuczynska, D.A.,Wu, I.J.,Murray, B.H.,Sheckler, L.R.,Rudenko, G. Regulation of Neurexin 1beta Tertiary Structure and Ligand Binding through Alternative Splicing Structure 2008 16 422 431
3BU1 18445596 Crystal structure of monomine-histamine complex 2007-12-31 2008-04-01 Mans, B.J.,Ribeiro, J.M.,Andersen, J.F. Structure, function, and evolution of biogenic amine-binding proteins in soft ticks. J.Biol.Chem. 2008 283 18721 18733
3BU9 18445596 Selenomethionine derivative of monomine L57,63,87,146M mutant 2008-01-02 2008-04-01 Mans, B.J.,Ribeiro, J.M.,Andersen, J.F. Structure, function, and evolution of biogenic amine-binding proteins in soft ticks. J.Biol.Chem. 2008 283 18721 18733
2H2Q 18536013 Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase 2006-05-19 2008-04-08 Schormann, N.,Senkovich, O.,Walker, K.,Wright, D.L.,Anderson, A.C.,Rosowsky, A.,Ananthan, S.,Shinkre, B.,Velu, S.,Chattopadhyay, D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins 2008 73 889 901
2Q1E 18400753 Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein. 2007-05-24 2008-04-08 Baden, E.M.,Owen, B.A.,Peterson, F.C.,Volkman, B.F.,Ramirez-Alvarado, M.,Thompson, J.R. Altered dimer interface decreases stability in an amyloidogenic protein. J.Biol.Chem. 2008 283 15853 15860
2Q20 18400753 Structure of the germline Vk1 O18/O8 light chain variable domain homodimer 2007-05-25 2008-04-08 Baden, E.M.,Owen, B.A.,Peterson, F.C.,Volkman, B.F.,Ramirez-Alvarado, M.,Thompson, J.R. Altered dimer interface decreases stability in an amyloidogenic protein. J.Biol.Chem. 2008 283 15853 15860
3B42 18329666 Periplasmic sensor domain of chemotaxis protein GSU0935 2007-10-23 2008-04-08 Pokkuluri, P.R.,Pessanha, M.,Londer, Y.Y.,Wood, S.J.,Duke, N.E.,Wilton, R.,Catarino, T.,Salgueiro, C.A.,Schiffer, M. Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction. J.Mol.Biol. 2008 377 1498 1517
3B47 18329666 Periplasmic sensor domain of chemotaxis protein GSU0582 2007-10-23 2008-04-08 Pokkuluri, P.R.,Pessanha, M.,Londer, Y.Y.,Wood, S.J.,Duke, N.E.,Wilton, R.,Catarino, T.,Salgueiro, C.A.,Schiffer, M. Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction. J.Mol.Biol. 2008 377 1498 1517
3CNI 25306867 Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8 2008-03-25 2008-04-08 Filippova, E.V.,Tkaczuk, K.L.,Chruszcz, M.,Xu, X.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8. J.Struct.Funct.Genom. 2014 15 215 222
3CNU Crystal structure of the predicted coding region AF_1534 from Archaeoglobus fulgidus 2008-03-26 2008-04-15 Zhang, R.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. The crystal structure of the predicted coding region AF_1534 from Archaeoglobus fulgidus. To be Published 0 0 0 0
3CNU Crystal structure of the predicted coding region AF_1534 from Archaeoglobus fulgidus 2008-03-26 2008-04-15 Zhang, R.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. The crystal structure of the predicted coding region AF_1534 from Archaeoglobus fulgidus. To be Published 0 0 0 0
3BCF 18387632 Alpha-amylase B from Halothermothrix orenii 2007-11-12 2008-04-22 Tan, T.-C.,Mijts, B.N.,Swaminathan, K.,Patel, B.K.C.,Divne, C. Crystal Structure of the Polyextremophilic alpha-Amylase AmyB from Halothermothrix orenii: Details of a Productive Enzyme-Substrate Complex and an N Domain with a Role in Binding Raw Starch J.Mol.Biol. 2008 378 850 868
3BTX 18432238 X-ray structure of human ABH2 bound to dsDNA through active site cross-linking 2007-12-31 2008-04-22 Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 2008 452 961 965
3BTY 18432238 Crystal structure of human ABH2 bound to dsDNA containing 1meA through cross-linking away from active site 2007-12-31 2008-04-22 Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 2008 452 961 965
3BTZ 18432238 Crystal structure of human ABH2 cross-linked to dsDNA 2007-12-31 2008-04-22 Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 2008 452 961 965
3BU0 18432238 crystal structure of human ABH2 cross-linked to dsDNA with cofactors 2007-12-31 2008-04-22 Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 2008 452 961 965
3BUC 18432238 X-ray structure of human ABH2 bound to dsDNA with Mn(II) and 2KG 2008-01-02 2008-04-22 Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 2008 452 961 965
3CRJ Crystal structure of a TetR transcription regulator from Haloarcula marismortui ATCC 43049 2008-04-07 2008-04-22 Tan, K.,Zhou, M.,Freeman, L.,Joachimiak, A. The crystal structure of a TetR transcription regulator from Haloarcula marismortui ATCC 43049. To be Published 0 0 0 0
2PNE 18598029 Crystal Structure of the Snow Flea Antifreeze Protein 2007-04-24 2008-04-29 Pentelute, B.L.,Gates, Z.P.,Tereshko, V.,Dashnau, J.L.,Vanderkooi, J.M.,Kossiakoff, A.A.,Kent, S.B. X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers J.Am.Chem.Soc. 2008 130 9695 9701
3CNV Crystal structure of the ligand-binding domain of a putative GntR-family transcriptional regulator from Bordetella bronchiseptica 2008-03-26 2008-04-29 Zimmerman, M.D.,Xu, X.,Cui, H.,Filippova, E.V.,Savchenko, A.,Edwards, A.M.,Minor, W. Structure of the ligand-binding domain of a putative GntR-family transcriptional regulator from Bordetella bronchiseptica. To be Published 0 0 0 0
3CQP 18378676 Human SOD1 G85R Variant, Structure I 2008-04-03 2008-04-29 Cao, X.,Antonyuk, S.V.,Seetharaman, S.V.,Whitson, L.J.,Taylor, A.B.,Holloway, S.P.,Strange, R.W.,Doucette, P.A.,Valentine, J.S.,Tiwari, A.,Hayward, L.J.,Padua, S.,Cohlberg, J.A.,Hasnain, S.S.,Hart, P.J. Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis. J.Biol.Chem. 2008 283 16169 16177
3CTV Crystal structure of central domain of 3-hydroxyacyl-CoA dehydrogenase from Archaeoglobus fulgidus 2008-04-14 2008-04-29 Osipiuk, J.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. X-ray crystal structure of central domain of 3-hydroxyacyl-CoA dehydrogenase from Archaeoglobus fulgidus. To be Published 0 0 0 0
3CWF 20008068 Crystal structure of PAS domain of two-component sensor histidine kinase 2008-04-21 2008-05-06 Chang, C.,Tesar, C.,Gu, M.,Babnigg, G.,Joachimiak, A.,Pokkuluri, P.R.,Szurmant, H.,Schiffer, M. Extracytoplasmic PAS-like domains are common in signal transduction proteins. J.Bacteriol. 2010 192 1156 1159
3CWF 20008068 Crystal structure of PAS domain of two-component sensor histidine kinase 2008-04-21 2008-05-06 Chang, C.,Tesar, C.,Gu, M.,Babnigg, G.,Joachimiak, A.,Pokkuluri, P.R.,Szurmant, H.,Schiffer, M. Extracytoplasmic PAS-like domains are common in signal transduction proteins. J.Bacteriol. 2010 192 1156 1159
3BZA 18492808 Structure of Mn-substituted Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.7 Ang resolution 2008-01-17 2008-05-13 Emerson, J.P.,Kovaleva, E.G.,Farquhar, E.R.,Lipscomb, J.D.,Que, L. Swapping metals in Fe- and Mn-dependent dioxygenases: evidence for oxygen activation without a change in metal redox state. Proc.Natl.Acad.Sci.Usa 2008 105 7347 7352
3CIT Crystal structure of the GAF domain of a putative sensor histidine kinase from Pseudomonas syringae pv. tomato 2008-03-11 2008-05-13 Cuff, M.E.,Li, H.,Abdullah, J.,Joachimiak, A. Crystal structure of the GAF domain of a putative sensor histidine kinase from Pseudomonas syringae pv. tomato To be Published 0 0 0 0
3CQB Crystal structure of heat shock protein HtpX domain from Vibrio parahaemolyticus RIMD 2210633 2008-04-02 2008-05-27 Wu, R.,Clancy, S.,Joachimiak, A. The crystal structure of heat shock protein HtpX domain from Vibrio parahaemolyticus RIMD 2210633. To be Published 0 0 0 0
3CXK 19020349 1.7 A Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei: crystallization in a microfluidic crystal card. 2008-04-24 2008-05-27 Gerdts, C.J.,Elliott, M.,Lovell, S.,Mixon, M.B.,Napuli, A.J.,Staker, B.L.,Nollert, P.,Stewart, L. The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS). Acta Crystallogr.,Sect.D 2008 64 1116 1122
2QMY Quinone Reductase 2 in complex with adrenochrome 2007-07-17 2008-06-24 Zhang, Z.,Fu, Y.,Buryanovskky, L. Quinone Reductase 2 regulates Catecholamine oxidation To be Published 0 0 0 0
2QMZ Quinone Reductase 2 in Complex with Dopamine 2007-07-17 2008-06-24 Fu, Y.,Buryanovskyy, L.,Zhang, Z. Quinone Reductase 2 Regulates Catecholamine Oxidation To be Published 0 0 0 0
3BEX 18186650 Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate 2007-11-20 2008-06-24 Yang, K.,Strauss, E.,Huerta, C.,Zhang, H. Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry 2008 47 1369 1380
3BF3 18186650 Type III pantothenate kinase from Thermotoga maritima complexed with product phosphopantothenate 2007-11-20 2008-06-24 Yang, K.,Strauss, E.,Huerta, C.,Zhang, H. Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry 2008 47 1369 1380
3BXH 18554327 Crystal structure of effector binding domain of central glycolytic gene regulator (CggR) from Bacillus subtilis in complex with fructose-6-phosphate 2008-01-13 2008-07-01 Rezacova, P.,Kozisek, M.,Moy, S.F.,Sieglova, I.,Joachimiak, A.,Machius, M.,Otwinowski, Z. Crystal structures of the effector-binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand-induced structural changes upon binding of several glycolytic intermediates. Mol.Microbiol. 2008 69 895 910
3BXU 18534185 PpcB, A Cytochrome c7 from Geobacter sulfurreducens 2008-01-14 2008-07-01 Morgado, L.,Bruix, M.,Orshonsky, V.,Londer, Y.Y.,Duke, N.E.,Yang, X.,Pokkuluri, P.R.,Schiffer, M.,Salgueiro, C.A. Structural insights into the modulation of the redox properties of two Geobacter sulfurreducens homologous triheme cytochromes. Biochim.Biophys.Acta 2008 1777 1157 1165
3D0G 18448527 Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus human strain complexed with human-civet chimeric receptor ACE2 2008-05-01 2008-07-08 Li, F. Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections J.Virol. 2008 82 6984 6991
3D0H 18448527 Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 2008-05-01 2008-07-08 Li, F. Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections J.Virol. 2008 82 6984 6991
3D0I 18448527 Crystal structure of spike protein receptor-binding domain from the 2005-2006 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 2008-05-01 2008-07-08 Li, F. Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections J.Virol. 2008 82 6984 6991
3D1L Crystal structure of putative NADP oxidoreductase BF3122 from Bacteroides fragilis 2008-05-06 2008-07-08 Chang, C.,Hendricks, R.,Abdullah, J.,Joachimiak, A. Crystal structure of putative NADP oxidoreductase BF3122 from Bacteroides fragilis. To be Published 0 0 0 0
3D6J Crystal structure of Putative haloacid dehalogenase-like hydrolase from Bacteroides fragilis 2008-05-19 2008-07-15 Chang, C.,Wu, R.,Cobb, G.,Joachimiak, A. Crystal structure of Putative haloacid dehalogenase-like hydrolase from Bacteroides fragilis To be Published 0 0 0 0
3D7N The crystal structure of the flavodoxin, WrbA-like protein from Agrobacterium tumefaciens 2008-05-21 2008-07-15 Zhang, R.,Xu, X.,Gu, J.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the flavodoxin, WrbA-like protein from Agrobacterium tumefaciens To be Published 2008 0 0 0
3D7N The crystal structure of the flavodoxin, WrbA-like protein from Agrobacterium tumefaciens 2008-05-21 2008-07-15 Zhang, R.,Xu, X.,Gu, J.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the flavodoxin, WrbA-like protein from Agrobacterium tumefaciens To be Published 2008 0 0 0
3DED C-terminal domain of Probable hemolysin from Chromobacterium violaceum 2008-06-09 2008-08-05 Chang, C.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of C-terminal domain of Probable hemolysin from Chromobacterium violaceum To be Published 0 0 0 0
3DM8 Crystal Structure of Putative Isomerase from Rhodopseudomonas palustris 2008-06-30 2008-08-05 Cymborowski, M.,Minor, W. Crystal Structure of Putative Isomerase from Rhodopseudomonas palustris To be Published 0 0 0 0
3DV9 Putative beta-phosphoglucomutase from Bacteroides vulgatus. 2008-07-18 2008-08-05 Osipiuk, J.,Tesar, C.,Clancy, S.,Joachimiak, A. X-ray crystal structure of putative beta-phosphoglucomutase from Bacteroides vulgatus. To be Published 0 0 0 0
3E0R Crystal structure of cppA protein from Streptococcus pneumoniae TIGR4 2008-07-31 2008-08-19 Nocek, B.,Mulligan, R.,Abdullah, S.,Otwinowski, Z.,Joachimiak, A. Crystal structure of cppA protein from Streptococcus pneumoniae TIGR4 To be Published 0 0 0 0
2R1T dopamine quinone conjugation to DJ-1 2007-08-23 2008-08-26 Zhongtao, Z.,Yue, F. DJ-1 is a proisopeptidase To be Published 0 0 0 0
2R1U DJ-1 activation by catechol quinone modification 2007-08-23 2008-08-26 Zhongtao, Z.,Yue, F. DJ-1 activation by catechol quinone modification To be Published 0 0 0 0
2R1V Norepinephrine quinone conjugation to DJ-1 2007-08-23 2008-08-26 Zhongtao, Z.,Yue, F. DJ-1 activation by catechol quinone conjugation To be Published 0 0 0 0
3E58 Crystal structure of putative beta-phosphoglucomutase from Streptococcus thermophilus 2008-08-13 2008-08-26 Chang, C.,Tesar, C.,Souvong, K.,Cobb, G.,Joachimiak, A. Crystal structure of putative beta-phosphoglucomutase from Streptococcus thermophilus To be Published 0 0 0 0
3B4V 18768470 X-Ray structure of Activin in complex with FSTL3 2007-10-24 2008-09-02 Stamler, R.,Keutmann, H.T.,Sidis, Y.,Kattamuri, C.,Schneyer, A.,Thompson, T.B. The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity. J.Biol.Chem. 2008 283 32831 32838
3BJ1 18831041 met-Perch Hemoglobin at pH 5.7 2007-12-02 2008-09-02 Aranda, R.,Cai, H.,Worley, C.E.,Levin, E.J.,Li, R.,Olson, J.S.,Phillips, G.N.,Richards, M.P. Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins 2008 75 217 230
3BJ2 18831041 met-Perch Hemoglobin at pH 6.3 2007-12-02 2008-09-02 Aranda, R.,Cai, H.,Worley, C.E.,Levin, E.J.,Li, R.,Olson, J.S.,Phillips, G.N.,Richards, M.P. Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins 2008 75 217 230
3BJ3 18831041 met-Perch hemoglobin at pH 8.0 2007-12-02 2008-09-02 Aranda, R.,Cai, H.,Worley, C.E.,Levin, E.J.,Li, R.,Olson, J.S.,Phillips, G.N.,Richards, M.P. Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins 2008 75 217 230
3CDY 18768467 AL-09 H87Y, immunoglobulin light chain variable domain 2008-02-27 2008-09-02 Baden, E.M.,Randles, E.G.,Aboagye, A.K.,Thompson, J.R.,Ramirez-Alvarado, M. Structural insights into the role of mutations in amyloidogenesis. J.Biol.Chem. 2008 283 30950 30956
3CPZ 19172746 Crystal structure of VAR2CSA DBL3x domain in the presence of dodecasaccharide of CSA 2008-04-01 2008-09-02 Singh, K.,Gittis, A.G.,Nguyen, P.,Gowda, D.C.,Miller, L.H.,Garboczi, D.N. Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A. Nat.Struct.Mol.Biol. 2008 15 932 938
3DNH The crystal structure of the protein Atu2129 (unknown function) from Agrobacterium tumefaciens str. C58 2008-07-02 2008-09-02 Tan, K.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the protein Atu2129 (unknown function) from Agrobacterium tumefaciens str. C58 To be Published 0 0 0 0
3DO8 The crystal structure of the protein with unknown function from Archaeoglobus fulgidus 2008-07-03 2008-09-02 Zhang, R.,Wu, R.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of the protein with unknown function from Archaeoglobus fulgidus To be Published 2008 0 0 0
3DS8 The crystal structure of the gene lin2722 products from Listeria innocua 2008-07-11 2008-09-16 Zhang, R.,Wu, R.,Freeman, L.,Joachimiak, A. The crysatl structure of the gene lin2722 products from Listeria innocua To be Published 0 0 0 0
3E9A Crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from Vibrio cholerae O1 biovar eltor str. N16961 2008-08-21 2008-09-16 Nocek, B.,Mulligan, R.,Kwon, K.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from Vibrio cholerae O1 biovar eltor str. N16961 To be Published 0 0 0 0
3EC6 Crystal structure of the General Stress Protein 26 from Bacillus anthracis str. Sterne 2008-08-29 2008-09-16 Kim, Y.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Anderson, W.F.,Joachimiak, A. Crystal structure of the general stress protein 26 from Bacillus anthracis str. Sterne To be Published 0 0 0 0
3ECT Crystal Structure of the Hexapeptide-Repeat Containing-Acetyltransferase VCA0836 from Vibrio cholerae 2008-09-02 2008-09-16 Kim, Y.,Maltseva, N.,Kwon, K.,Papazisi, L.,Hasseman, J.,Peterson, S.,Anderson, W.F.,Joachimiak, A. Crystal Structure of the Hexapeptide-Repeat Containing-Acetyltransferase VCA0836 from Vibrio cholerae To be Published 0 0 0 0
3ED5 The crystal structure of YfnB from Bacillus subtilis subsp. subtilis str. 168 2008-09-02 2008-09-16 Tan, K.,Wu, R.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of YfnB from Bacillus subtilis subsp. subtilis str. 168 To be Published 0 0 0 0
3EEV Crystal Structure of Chloramphenicol Acetyltransferase VCA0300 from Vibrio cholerae O1 biovar eltor 2008-09-05 2008-09-16 Kim, Y.,Maltseva, N.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Chloramphenicol Acetyltransferase VCA0300 from Vibrio cholerae O1 biovar eltor To be Published 0 0 0 0
3D9C 18781746 Crystal Structure PTP1B complex with aryl Seleninic acid 2008-05-27 2008-09-23 Abdo, M.,Liu, S.,Zhou, B.,Walls, C.D.,Wu, L.,Knapp, S.,Zhang, Z.Y. Seleninate in place of phosphate: irreversible inhibition of protein tyrosine phosphatases. J.Am.Chem.Soc. 2008 130 13196 13197
3EFB Crystal Structure of Probable sor Operon Regulator from Shigella flexneri 2008-09-08 2008-09-23 Kim, Y.,Evdokimova, E.,Kudritska, M.,Savchenko, A.,Edwards, A.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Probable sor Operon Regulator from Shigella flexneri To be Published 0 0 0 0
3EFE The crystal structure of the thiJ/pfpI family protein from Bacillus anthracis 2008-09-08 2008-09-23 Zhang, R.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Anderson, W.,Joachimiak, A. The crystal structure of the thiJ/pfpI family protein from Bacillus anthracis To be Published 0 0 0 0
3BEN 18298086 Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3 2007-11-19 2008-09-30 Haines, D.C.,Chen, B.,Tomchick, D.R.,Bondlela, M.,Hegde, A.,Machius, M.,Peterson, J.A. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. Biochemistry 2008 47 3662 3670
3DCI The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 2008-06-03 2008-09-30 Cuff, M.E.,Xu, X.,Zheng, H.,Binkowski, T.A.,Edwards, A.,Savchenko, A.,Joachimiak, A. The Structure of a putative arylesterase from Agrobacterium tumefaciens str. C58 TO BE PUBLISHED 0 0 0 0
3DDH The structure of a putative haloacid dehalogenase-like family hydrolase from Bacteroides thetaiotaomicron VPI-5482 2008-06-05 2008-09-30 Cuff, M.E.,Duggan, E.,Abdullah, J.,Joachimiak, A. The structure of a putative haloacid dehalogenase-like family hydrolase from Bacteroides thetaiotaomicron VPI-5482 TO BE PUBLISHED 0 0 0 0
3ECJ 18826259 Structure of E323L mutant of Homoprotocatechuate 2,3-Dioxygenase from Brevibacterium fuscum at 1.65A resolution 2008-08-31 2008-10-07 Kovaleva, E.G.,Lipscomb, J.D. Intermediate in the O-O Bond Cleavage Reaction of an Extradiol Dioxygenase. Biochemistry 2008 47 11168 11170
3ECK 18826259 Structure of E323L Homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum in complex with putative O-O bond cleavage intermediate formed via in crystallo reaction with 4-sulfonyl catechol at low oxygen concentrations 2008-08-31 2008-10-07 Kovaleva, E.G.,Lipscomb, J.D. Intermediate in the O-O Bond Cleavage Reaction of an Extradiol Dioxygenase. Biochemistry 2008 47 11168 11170
3DR4 18795799 GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand 2008-07-10 2008-10-14 Cook, P.D.,Carney, A.E.,Holden, H.M. Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase Biochemistry 2008 47 10685 10693
2RHH 19383143 Synthetic Gene Encoded Bacillus Subtilis FtsZ with Bound Sulfate Ion 2007-10-09 2008-10-21 Raymond, A.,Lovell, S.,Lorimer, D.,Walchli, J.,Mixon, M.,Wallace, E.,Thompkins, K.,Archer, K.,Burgin, A.,Stewart, L. Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer. BMC Biotechnol. 2009 9 37 37
2RHJ 19383143 Synthetic Gene Encoded Bacillus Subtilis FtsZ with Two Sulfate Ions and Sodium Ion in the Nucleotide Pocket 2007-10-09 2008-10-21 Raymond, A.,Lovell, S.,Lorimer, D.,Walchli, J.,Mixon, M.,Wallace, E.,Thompkins, K.,Archer, K.,Burgin, A.,Stewart, L. Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer. BMC Biotechnol. 2009 9 37 37
2RHL 19383143 Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP 2007-10-09 2008-10-21 Raymond, A.,Lovell, S.,Lorimer, D.,Walchli, J.,Mixon, M.,Wallace, E.,Thompkins, K.,Archer, K.,Burgin, A.,Stewart, L. Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer. BMC Biotechnol. 2009 9 37 37
2RHO 19383143 Synthetic Gene Encoded Bacillus Subtilis FtsZ NCS Dimer with Bound GDP and GTP-gamma-S 2007-10-09 2008-10-21 Raymond, A.,Lovell, S.,Lorimer, D.,Walchli, J.,Mixon, M.,Wallace, E.,Thompkins, K.,Archer, K.,Burgin, A.,Stewart, L. Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer. BMC Biotechnol. 2009 9 37 37
3CU4 18837462 OmcF, Outer membrance cytochrome F from Geobacter sulfurreducens 2008-04-15 2008-10-21 Pokkuluri, P.R.,Londer, Y.Y.,Wood, S.J.,Duke, N.E.,Morgado, L.,Salgueiro, C.A.,Schiffer, M. Outer membrane cytochrome c, OmcF, from Geobacter sulfurreducens: High structural similarity to an algal cytochrome c(6). Proteins 2008 74 266 270
3EER High resolution structure of putative organic hydroperoxide resistance protein from Vibrio cholerae O1 biovar eltor str. N16961 2008-09-05 2008-10-21 Nocek, B.,Mulligan, R.,Kwon, K.,Anderson, W.F.,Joachimiak, A. High resolution crystal structure of the organic hydroperoxide resistance protein from Vibrio cholerae O1 biovar eltor str. N16961 To be Published 0 0 0 0
3BNV 18835274 Crystal structure of Cj0977, a sigma28-regulated virulence protein from Campylobacter jejuni. 2007-12-14 2008-10-28 Yokoyama, T.,Paek, S.,Ewing, C.P.,Guerry, P.,Yeo, H.J. Structure of a sigma28-regulated nonflagellar virulence protein from Campylobacter jejuni. J.Mol.Biol. 2008 384 364 376
3EWL Crystal Structure of Conserved protein BF1870 of Unknown Function from Bacteroides fragilis 2008-10-15 2008-10-28 Kim, Y.,Tesar, C.,Cobb, G.,Joachimiak, A. Crystal Structure of Conserved protein BF1870 of Unknown Function from Bacteroides fragilis To be Published 0 0 0 0
3F0I Arsenate reductase from Vibrio cholerae. 2008-10-24 2008-11-11 Osipiuk, J.,Gu, M.,Stam, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of Arsenate reductase from Vibrio cholerae. To be Published 0 0 0 0
3EY5 Putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron. 2008-10-17 2008-11-18 Osipiuk, J.,Bigelow, L.,Clancy, S.,Joachimiak, A. X-ray crystal structure of putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron. To be Published 0 0 0 0
3F5B The crystal structure of aminoglycoside N(6')acetyltransferase from Legionella pneumophila subsp. pneumophila str. Philadelphia 1. 2008-11-03 2008-11-18 Tan, K.,Wu, R.,Perez, V.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of aminoglycoside N(6')acetyltransferase from Legionella pneumophila subsp. pneumophila str. Philadelphia 1. To be Published 0 0 0 0
3F5R The crystal structure of a subunit of the heterodimeric FACT complex (Spt16p-Pob3p). 2008-11-04 2008-11-18 Tan, K.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of a subunit of the heterodimeric FACT complex (Spt16p-Pob3p). To be Published 0 0 0 0
3CCK 18959746 Human CD69 2008-02-26 2008-11-25 Vanek, O.,Nalezkova, M.,Kavan, D.,Borovickova, I.,Pompach, P.,Novak, P.,Kumar, V.,Vannucci, L.,Hudecek, J.,Hofbauerova, K.,Kopecky, V.,Brynda, J.,Kolenko, P.,Dohnalek, J.,Kaderavek, P.,Chmelik, J.,Gorcik, L.,Zidek, L.,Sklenar, V.,Bezouska, K. Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice Febs J. 2008 275 5589 5606
3F4N Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis 2008-11-01 2008-11-25 Kim, Y.,Maltseva, N.,Stam, J.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis To be Published 2008 0 0 0
3F67 Crystal Structure of Putative Dienelactone Hydrolase from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 2008-11-05 2008-11-25 Kim, Y.,Li, H.,Bearden, J.,Joachimiak, A. Crystal Structure of Putative Dienelactone Hydrolase from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 To be Published 0 0 0 0
3ETW 18996848 Crystal Structure of bacterial adhesin FadA 2008-10-08 2008-12-02 Nithianantham, S.,Xu, M.,Yamada, M.,Ikegami, A.,Shoham, M.,Han, Y.W. Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem. 2009 284 3865 3872
3ETX 18996848 Crystal structure of bacterial adhesin FadA L14A mutant 2008-10-08 2008-12-02 Nithianantham, S.,Xu, M.,Yamada, M.,Ikegami, A.,Shoham, M.,Han, Y.W. Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem. 2009 284 3865 3872
3ETY 18996848 Crystal structure of bacterial adhesin FadA L14A mutant 2008-10-08 2008-12-02 Nithianantham, S.,Xu, M.,Yamada, M.,Ikegami, A.,Shoham, M.,Han, Y.W. Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem. 2009 284 3865 3872
3ETZ 18996848 Crystal structure of bacterial adhesin FadA L76A mutant 2008-10-08 2008-12-02 Nithianantham, S.,Xu, M.,Yamada, M.,Ikegami, A.,Shoham, M.,Han, Y.W. Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem. 2009 284 3865 3872
3EUR Crystal structure of the C-terminal domain of uncharacterized protein from Bacteroides fragilis NCTC 9343 2008-10-10 2008-12-02 Nocek, B.,Tesar, C.,Cobb, G.,Joachimiak, A. Crystal structure of the C-terminal domain of uncharacterized protein from Bacteroides fragilis NCTC 9343 To be Published 0 0 0 0
3EYO 18772881 Crystal structure of anti-human cytomegalovirus antibody 8F9 2008-10-21 2008-12-16 Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J. 2008 27 2592 2602
3FDX Putative filament protein / universal stress protein F from Klebsiella pneumoniae. 2008-11-26 2008-12-16 Osipiuk, J.,Volkart, L.,Bearden, J.,Joachimiak, A. X-ray crystal structure of putative filament protein / universal stress protein F from Klebsiella pneumoniae. To be Published 0 0 0 0
3E83 19098915 Crystal Structure of the the open NaK channel pore 2008-08-19 2008-12-23 Alam, A.,Jiang, Y. Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol. 2009 16 35 41
3E89 19098915 Crystal Structure of the the open NaK channel-low Na+ complex 2008-08-19 2008-12-23 Alam, A.,Jiang, Y. Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol. 2009 16 35 41
3E8B 19098915 Crystal Structure of the the open NaK channel- Rb+ complex 2008-08-19 2008-12-23 Alam, A.,Jiang, Y. Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol. 2009 16 35 41
3E8F 19098915 Crystal Structure of the the open NaK channel- K+/Ba2+ 2008-08-19 2008-12-23 Alam, A.,Jiang, Y. Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol. 2009 16 35 41
3E8H 19098915 Crystal Structure of the the open NaK channel-K+ complex 2008-08-19 2008-12-23 Alam, A.,Jiang, Y. Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol. 2009 16 35 41
3FBS The crystal structure of the oxidoreductase from Agrobacterium tumefaciens 2008-11-19 2008-12-23 Zhang, R.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the oxidoreductase from Agrobacterium tumefaciens To be Published 2008 0 0 0
3FBS The crystal structure of the oxidoreductase from Agrobacterium tumefaciens 2008-11-19 2008-12-23 Zhang, R.,Xu, X.,Zheng, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the oxidoreductase from Agrobacterium tumefaciens To be Published 2008 0 0 0
3FH0 Crystal structure of putative universal stress protein KPN_01444 - ATPase 2008-12-08 2008-12-23 Chang, C.,Li, H.,Bearden, J.,Joachimiak, A. Crystal structure of putative universal stress protein KPN_01444 - ATPase To be Published 0 0 0 0
3FH2 The crystal structure of the PROBABLE ATP-DEPENDENT PROTEASE (HEAT SHOCK PROTEIN) from Corynebacterium glutamicum 2008-12-08 2008-12-23 Zhang, R.,Li, H.,Freeman, L.,Joachimiak, A. The crystal structure of the PROBABLE ATP-DEPENDENT PROTEASE (HEAT SHOCK PROTEIN) from Corynebacterium glutamicum To be Published 0 0 0 0
3EXN Crystal structure of acetyltransferase from Thermus thermophilus HB8 2008-10-16 2009-01-06 Nocek, B.,Hatzos, C.,Clancy, S.,Joachimiak, A. Crystal structure of acetyltransferase from Thermus thermophilus HB8 To be Published 0 0 0 0
3FGG Crystal Structure of Putative ECF-type Sigma Factor Negative Effector from Bacillus cereus 2008-12-05 2009-01-06 Kim, Y.,Nocek, B.,Maltseva, N.,Joachimiak, G.,Du, J.,Jedrzejczak, R.,Joachimiak, A. Crystal Structure of Putative ECF-type Sigma Factor Negative Effector from Bacillus cereus To be Published 0 0 0 0
3FOB Crystal structure of bromoperoxidase from Bacillus anthracis 2008-12-29 2009-01-06 Osipiuk, J.,Gu, M.,Stam, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of bromoperoxidase from Bacillus anthracis. To be Published 0 0 0 0
3FLE SE_1780 protein of unknown function from Staphylococcus epidermidis. 2008-12-18 2009-01-13 Osipiuk, J.,Hatzos, C.,Clancy, S.,Joachimiak, A. X-ray crystal structure of SE_1780 protein of unknown function from Staphylococcus epidermidis. To be Published 0 0 0 0
3FOV Crystal structure of protein RPA0323 of unknown function from Rhodopseudomonas palustris 2009-01-02 2009-01-13 Osipiuk, J.,Skarina, T.,Kagan, O.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. X-ray crystal structure of protein RPA0323 of unknown function from Rhodopseudomonas palustris. To be Published 0 0 0 0
3F1O 19129502 Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand 2008-10-28 2009-01-20 Scheuermann, T.H.,Tomchick, D.R.,Machius, M.,Guo, Y.,Bruick, R.K.,Gardner, K.H. Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor. Proc.Natl.Acad.Sci.USA 2009 106 450 455
3FG8 Crystal structure of PAS domain of RHA05790 2008-12-05 2009-01-20 Chang, C.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of PAS domain of RHA05790 To be Published 0 0 0 0
3FKF thiol-disulfide oxidoreductase from Bacteroides fragilis NCTC 9343 2008-12-16 2009-01-20 Duke, N.E.C.,Freeman, L.,Tesar, C.,Joachimiak, A. thiol-disulfide oxidoreductase from Bacteroides fragilis NCTC 9343 To be Published 0 0 0 0
3FN2 Crystal structure of a putative sensor histidine kinase domain from Clostridium symbiosum ATCC 14940 2008-12-23 2009-01-27 Cuff, M.E.,Tesar, C.,Freeman, L.,Joachimiak, A. The structure of a putative sensor histidine kinase domain from Clostridium symbiosum ATCC 14940 TO BE PUBLISHED 0 0 0 0
3FNA Crystal structure of the CBS pair of possible D-arabinose 5-phosphate isomerase yrbH from Escherichia coli CFT073 2008-12-23 2009-01-27 Cuff, M.E.,Bigelow, L.,Buck, K.,Joachimiak, A. The CBS Pair of possible D-arabinose 5-phosphate isomerase yrbH from Escherichia coli CFT073 TO BE PUBLISHED 0 0 0 0
3FNC Crystal structure of a putative acetyltransferase from Listeria innocua 2008-12-24 2009-01-27 Cuff, M.E.,Tesar, C.,Freeman, L.,Joachimiak, A. The structure of a putative acetyltransferase from Listeria innocua. TO BE PUBLISHED 0 0 0 0
3FW2 C-terminal domain of putative thiol-disulfide oxidoreductase from Bacteroides thetaiotaomicron. 2009-01-16 2009-01-27 Osipiuk, J.,Li, H.,Cobb, G.,Joachimiak, A. X-ray crystal structure of C-terminal domain of putative thiol-disulfide oxidoreductase from Bacteroides thetaiotaomicron. To be Published 0 0 0 0
3DYE 19234127 Crystal structure of AED7-norepineprhine complex 2008-07-27 2009-02-03 Calvo, E.,Mans, B.J.,Ribeiro, J.M.,Andersen, J.F. Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein Proc.Natl.Acad.Sci.USA 2009 106 3728 3733
3FPI Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase IspF complexed with Cytidine Triphosphate 2009-01-05 2009-02-03 Kim, Y.,Maltseva, N.,Stam, J.,Anderson, W.F.,Joachimiak, A. Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase IspF complexed with Cytidine Triphosphate To be Published 0 0 0 0
3DAK 19177573 Crystal Structure of Domain-Swapped OSR1 kinase domain 2008-05-29 2009-02-10 Lee, S.J.,Cobb, M.H.,Goldsmith, E.J. Crystal structure of domain-swapped STE20 OSR1 kinase domain. Protein Sci. 2008 18 304 313
3FYN Crystal structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3 2009-01-22 2009-02-10 Sureshan, V.,Deshpande, C.,Harrop, S.J.,Kudritska, M.,Koenig, J.E.,Evdokimova, E.,Osipiuk, J.,Edwards, A.M.,Savchenko, A.,Joachimiak, A.,Doolittle, W.F.,Stokes, H.W.,Curmi, P.M.G.,Mabbutt, B.C. Structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3 To be Published 0 0 0 0
3G0S Dihydrodipicolinate synthase from Salmonella typhimurium LT2 2009-01-28 2009-02-10 Osipiuk, J.,Maltseva, N.,Stam, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of dihydrodipicolinate synthase from Salmonella typhimurium LT2. To be Published 0 0 0 0
2ZXX 15286659 Crystal structure of Cdt1/geminin complex 2009-01-08 2009-02-17 Lee, C.,Hong, B.S.,Choi, J.M.,Kim, Y.,Watanabe, S.,Ishimi, Y.,Enomoto, T.,Tada, S.,Kim, Y.,Cho, Y. Structural basis for inhibition of the replication licensing factor Cdt1 by geminin Nature 2004 430 913 917
3CIK 20128603 Human GRK2 in Complex with Gbetagamma subunits 2008-03-11 2009-02-17 Tesmer, J.J.,Tesmer, V.M.,Lodowski, D.T.,Steinhagen, H.,Huber, J. Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem. 2010 53 1867 1870
3FRK 19178182 X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine 2009-01-08 2009-02-17 Thoden, J.B.,Schaffer, C.,Messner, P.,Holden, H.M. Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose. Biochemistry 2009 48 1553 1561
3FXH 23349695 Crystal structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS2 2009-01-20 2009-02-17 Sureshan, V.,Deshpande, C.N.,Boucher, Y.,Koenig, J.E.,Stokes, H.W.,Harrop, S.J.,Curmi, P.M.,Mabbutt, B.C. Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. Plos One 2013 8 0 0
3G1J Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS4. 2009-01-30 2009-02-24 Deshpande, C.N.,Sureshan, V.,Harrop, S.J.,Boucher, Y.,Xu, X.,Cui, H.,Edwards, A.,Savchenko, A.,Joachimiak, A.,Tan, K.,Stokes, H.W.,Curmi, P.M.G.,Mabbutt, B.C. Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS4. To be published 0 0 0 0
3ENM 19141286 The structure of the MAP2K MEK6 reveals an autoinhibitory dimer 2008-09-25 2009-03-03 Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.E.,Lee, S.J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J. The structure of the MAP2K MEK6 reveals an autoinhibitory dimer Structure 2009 17 96 104
3FN8 Crystal Structure of MerB complexed with mercury 2008-12-23 2009-03-03 Momany, C.,Summers, A.,Cagle, C.,Teske, J. Crystal Structure of MerB complexed with mercury TO BE PUBLISHED 0 0 0 0
3FTT 23963951 Crystal Structure of the galactoside O-acetyltransferase from Staphylococcus aureus 2009-01-13 2009-03-03 Luo, H.B.,Knapik, A.A.,Petkowski, J.J.,Demas, M.,Shumilin, I.A.,Zheng, H.,Chruszcz, M.,Minor, W. Biophysical analysis of the putative acetyltransferase SACOL2570 from methicillin-resistant Staphylococcus aureus. J.Struct.Funct.Genom. 2013 14 97 108
3FDD 19265705 The Crystal Structure of the Pseudomonas dacunhae Aspartate-Beta-Decarboxylase Reveals a Novel Oligomeric Assembly for a Pyridoxal-5-Phosphate Dependent Enzyme 2008-11-25 2009-03-17 Lima, S.,Sundararaju, B.,Huang, C.,Khristoforov, R.,Momany, C.,Phillips, R.S. The crystal structure of the Pseudomonas dacunhae aspartate-beta-decarboxylase dodecamer reveals an unknown oligomeric assembly for a pyridoxal-5'-phosphate-dependent enzyme. J.Mol.Biol. 2009 388 98 108
1VSU 19243605 Crystal Structure of Apo-glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum 2008-03-10 2009-03-24 Cook, W.J.,Senkovich, O.,Chattopadhyay, D. An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme BMC STRUCT.BIOL. 2009 9 9 9
1VSV 19243605 Crystal Structure of holo-glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum 2008-03-11 2009-03-24 Cook, W.J.,Senkovich, O.,Chattopadhyay, D. An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme BMC STRUCT.BIOL. 2009 9 9 9
3COP 19244233 Crystal Structure of E.coli GS mutant E377A in complex with ADP and acceptor analogue HEPPSO 2008-03-28 2009-03-24 Sheng, F.,Jia, X.,Yep, A.,Preiss, J.,Geiger, J.H. The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase. J.Biol.Chem. 2009 284 17796 17807
3FX3 Structure of a putative cAMP-binding regulatory protein from Silicibacter pomeroyi DSS-3 2009-01-19 2009-03-24 Cuff, M.E.,Zhou, M.,Freeman, L.,Joachimiak, A. Structure of a putative cAMP-binding regulatory protein from Silicibacter pomeroyi DSS-3 TO BE PUBLISHED 0 0 0 0
3G27 Structure of a putative bacteriophage protein from Escherichia coli str. K-12 substr. MG1655 2009-01-30 2009-03-24 Cuff, M.E.,Evdokimova, E.,Kudritska, M.,Edwards, A.,Savchenko, A.,Joachimiak, A. Structure of a putative bacteriophage protein from Escherichia coli str. K-12 substr. MG1655 TO BE PUBLISHED 0 0 0 0
3GHJ Crystal structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4 2009-03-03 2009-03-24 Sureshan, V.,Deshpande, C.,Harrop, S.J.,Kudritska, M.,Koenig, J.E.,Evdokimova, E.,Kim, Y.,Edwards, A.M.,Savchenko, A.,Joachimiak, A.,Doolittle, W.F.,Stokes, H.W.,Curmi, P.M.G.,Mabbutt, B.C. Structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4 To be Published 0 0 0 0
3GKX Crystal structure of putative ArsC family related protein from Bacteroides fragilis 2009-03-11 2009-03-24 Chang, C.,Tesar, C.,Freeman, L.,Joachimiak, A. Crystal structure of putative ArsC family related protein from Bacteroides fragilis To be Published 0 0 0 0
3GN3 Crystal structure of a putative protein-disulfide isomerase from Pseudomonas syringae to 2.5A resolution. 2009-03-16 2009-03-31 Stein, A.J.,Chhor, G.,Freeman, L.,Joachimiak, A. Crystal structure of a putative protein-disulfide isomerase from Pseudomonas syringae to 2.5A resolution. To be Published 0 0 0 0
3GQS Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis 2009-03-24 2009-04-07 Majorek, K.A.,Cymborowski, M.,Chruszcz, M.,Evdokimova, E.,Egorova, O.,Di Leo, R.,Zimmerman, M.D.,Savchenko, A.,Joachimiak, A.,Edwards, A.M.,Minor, W. Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis To be Published 0 0 0 0
3D6L 19303060 Crystal structure of Cj0915, a hexameric hotdog fold thioesterase of Campylobacter jejuni 2008-05-19 2009-05-05 Yokoyama, T.,Choi, K.J.,Bosch, A.M.,Yeo, H.J. Structure and function of a Campylobacter jejuni thioesterase Cj0915, a hexameric hot dog fold enzyme. Biochim.Biophys.Acta 2009 1794 1073 1081
3D6X 19280690 Crystal structure of Campylobacter jejuni FabZ 2008-05-20 2009-05-05 Kirkpatrick, A.S.,Yokoyama, T.,Choi, K.J.,Yeo, H.J. Campylobacter jejuni fatty acid synthase II: structural and functional analysis of beta-hydroxyacyl-ACP dehydratase (FabZ). Biochem.Biophys.Res.Commun. 2009 380 407 412
3FOT 19319932 Structural and Functional Characterization of TRI3 Trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides 2009-01-01 2009-05-05 Garvey, G.S.,McCormick, S.P.,Alexander, N.J.,Rayment, I. Structural and functional characterization of TRI3 trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides Protein Sci. 2009 18 747 761
3GSE Crystal structure of menaquinone-specific isochorismate synthase from Yersinia pestis CO92 2009-03-26 2009-05-05 Nocek, B.,Gu, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Crystal structure of menaquinone-specific isochorismate synthase from Yersinia pestis CO92 To be Published 0 0 0 0
3H07 Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Yersinia pestis CO92 2009-04-08 2009-05-05 Nocek, B.,Gu, M.,Kwon, K.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Yersinia pestis CO92 To be Published 0 0 0 0
3EHM 19191477 Structure of BT1043 2008-09-13 2009-05-12 Koropatkin, N.,Martens, E.C.,Gordon, J.I.,Smith, T.J. Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont. Biochemistry 2009 48 1532 1542
3GMI Crystal structure of a protein of unknown function from Methanocaldococcus jannaschii 2009-03-13 2009-05-12 Zhang, R.,Hatzos, C.,Freeman, L.,Joachimiak, A. The crystal structure of the protein with unknown function from Methanocaldococcus jannaschii To be Published 0 0 0 0
3GNJ The crystal structure of a thioredoxin-related protein from Desulfitobacterium hafniense DCB 2009-03-17 2009-05-12 Tan, K.,Volkart, L.,Gu, M.,Kinney, J.N.,Babnigg, G.,Kerfeld, C.,Joachimiak, A. The crystal structure of a thioredoxin-related protein from Desulfitobacterium hafniense DCB To be Published 0 0 0 0
3FV3 19401235 Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A 2009-01-15 2009-05-19 Dostal, J.,Brynda, J.,Hruskova-Heidingsfeldova, O.,Sieglova, I.,Pichova, I.,Rezacova, P. The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A J.Struct.Biol. 2009 167 145 152
3HJJ Crystal Structure of Maltose O-acetyltransferase from Bacillus anthracis 2009-05-21 2009-06-02 Kim, Y.,Maltseva, N.,Papazisi, L.,Anderson, W.,Joachimiak, A. Crystal Structure of Maltose O-acetyltransferase from Bacillus anthracis To be Published 0 0 0 0
3GYK The crystal structure of a thioredoxin-like oxidoreductase from Silicibacter pomeroyi DSS-3 2009-04-03 2009-06-09 Fan, Y.,Marshall, N.,Keigher, L.,Joachimiak, A. The crystal structure of a thioredoxin-like oxidoreductase from Silicibacter pomeroyi DSS-3 To be Published 0 0 0 0
3HFR Crystal structure of glutamate racemase from Listeria monocytogenes 2009-05-12 2009-06-09 Majorek, K.A.,Chruszcz, M.,Zimmerman, M.D.,Klimecka, M.M.,Cymborowski, M.,Skarina, T.,Onopriyenko, O.,Stam, J.,Otwinowski, Z.,Anderson, W.F.,Savchenko, A.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of glutamate racemase from Listeria monocytogenes TO BE PUBLISHED 0 0 0 0
3D3V 19698083 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide 2008-05-12 2009-06-16 Piepenbrink, K.H.,Borbulevych, O.Y.,Sommese, R.F.,Clemens, J.,Armstrong, K.M.,Desmond, C.,Do, P.,Baker, B.M. Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner. Biochem.J. 2009 423 353 361
3H2Z The crystal structure of mannitol-1-phosphate dehydrogenase from Shigella flexneri 2009-04-15 2009-06-16 Wu, R.,Clancy, S.,Joachimiak, A. The crystal structure of mannitol-1-phosphate dehydrogenase from Shigella flexneri To be Published 0 0 0 0
3HE1 21476004 Secreted protein Hcp3 from Pseudomonas aeruginosa. 2009-05-07 2009-06-16 Osipiuk, J.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of secretory protein Hcp3 from Pseudomonas aeruginosa. J.Struct.Funct.Genom. 2011 12 21 26
3HL0 Crystal structure of Maleylacetate reductase from Agrobacterium tumefaciens 2009-05-26 2009-06-16 Chang, C.,Evdokimova, E.,Mursleen, A.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of Maleylacetate reductase from Agrobacterium tumefaciens To be Published 0 0 0 0
3HQX Crystal structure of protein of unknown function (DUF1255,PF06865) from Acinetobacter sp. ADP1 2009-06-08 2009-06-30 Nocek, B.,Hatzos, C.,Freeman, L.,Dauter, Z.,Joachimiak, A. Crystal structure of protein of unknown function (DUF1255,PF06865) from Acinetobacter sp. ADP1 To be Published 0 0 0 0
3HYL Crystal Structure of Transketolase from Bacillus anthracis 2009-06-22 2009-06-30 Maltseva, N.,Kim, Y.,Kwon, K.,Joachimiak, A.,Anderson, W.F. Crystal Structure of Transketolase from Bacillus anthracis To be Published 0 0 0 0
3HYQ Crystal Structure of Isopentenyl-Diphosphate delta-Isomerase from Salmonella entericase 2009-06-22 2009-06-30 Kim, Y.,Zhou, M.,Peterson, S.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Isopentenyl-Diphosphate delta-Isomerase from Salmonella entericase To be Published 0 0 0 0
3GAH 19236001 Structure of a F112H variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP 2009-02-17 2009-07-07 Mera, P.E.,St Maurice, M.,Rayment, I.,Escalante-Semerena, J.C. Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry 2009 48 3138 3145
3GAI 19236001 Structure of a F112A variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP 2009-02-17 2009-07-07 Mera, P.E.,St Maurice, M.,Rayment, I.,Escalante-Semerena, J.C. Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry 2009 48 3138 3145
3GAJ 19236001 Structure of a C-terminal deletion variant of a PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP 2009-02-17 2009-07-07 Mera, P.E.,St Maurice, M.,Rayment, I.,Escalante-Semerena, J.C. Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry 2009 48 3138 3145
3HHL Crystal structure of methylated RPA0582 protein 2009-05-15 2009-07-07 Sledz, P.,Niedzialkowska, E.,Chruszcz, M.,Porebski, P.,Yim, V.,Kudritska, M.,Zimmerman, M.D.,Evdokimova, E.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Minor, W. Crystal structure of methylated RPA0582 protein To be Published 0 0 0 0
3HSE 19586910 Crystal structure of Staphylococcus aureus protein SarZ in reduced form 2009-06-10 2009-07-07 Poor, C.B.,Chen, P.R.,Duguid, E.,Rice, P.A.,He, C. Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus. J.Biol.Chem. 2009 284 23517 23524
3HNW Crystal Structure of a Basic Coiled-Coil Protein of Unknown Function from Eubacterium eligens ATCC 27750 2009-06-01 2009-07-14 Kim, Y.,Cuff, M.,Hendricks, R.,Keigher, L.,Joachimiak, A. Crystal Structure of a Basic Coiled-Coil Protein of Unknown Function from Eubacterium eligens ATCC 27750 To be Published 0 0 0 0
3I7M N-terminal domain of Xaa-Pro dipeptidase from Lactobacillus brevis. 2009-07-08 2009-07-14 Osipiuk, J.,Xu, X.,Cui, H.,Ng, J.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. X-ray crystal structure of N-terminal domain of Xaa-Pro dipeptidase from Lactobacillus brevis. To be Published 0 0 0 0
3HSM 19541610 Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1 2009-06-10 2009-07-28 Amador, F.J.,Liu, S.,Ishiyama, N.,Plevin, M.J.,Wilson, A.,MacLennan, D.H.,Ikura, M. Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation ""hot spot"" loop Proc.Natl.Acad.Sci.USA 2009 106 11040 11044
3I4P Crystal structure of AsnC family transcriptional regulator from Agrobacterium tumefaciens 2009-07-02 2009-07-28 Cymborowski, M.,Chruszcz, M.,Luo, H.,Xu, X.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Minor, W. Crystal structure of AsnC family transcriptional regulator from Agrobacterium tumefaciens To be Published 0 0 0 0
3IGJ Crystal Structure of Maltose O-acetyltransferase Complexed with Acetyl Coenzyme A from Bacillus anthracis 2009-07-27 2009-08-04 Maltseva, N.,Kim, Y.,Papazisi, L.,Anderson, W.,Joachimiak, A. Crystal Structure of Maltose O-acetyltransferase Complexed with Acetyl Coenzyme A from Bacillus anthracis To be Published 0 0 0 0
3GGU 19535439 HIV PR drug resistant patient's variant in complex with darunavir 2009-03-02 2009-08-11 Saskova, K.G.,Kozisek, M.,Rezacova, P.,Brynda, J.,Yashina, T.,Kagan, R.M.,Konvalinka, J. Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir. J.Virol. 2009 83 8810 8818
3IH2 20161694 TM1030 crystallized at 323K 2009-07-29 2009-08-11 Koclega, K.D.,Chruszcz, M.,Zimmerman, M.D.,Bujacz, G.,Minor, W. 'Hot' macromolecular crystals. Cryst.Growth Des. 2010 10 580 586
3EGY 19569192 Crystal Structure of Human Thymidyalte Synthase A191K with Loop 181-197 stabilized in the inactive conformation 2008-09-11 2009-08-18 Lovelace, L.L.,Johnson, S.R.,Gibson, L.M.,Bell, B.J.,Berger, S.H.,Lebioda, L. Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation. Protein Sci. 2009 18 1628 1636
3IC4 The crystal structure of the glutaredoxin(grx-1) from Archaeoglobus fulgidus 2009-07-17 2009-08-18 Zhang, R.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the glutaredoxin from Archaeoglobus fulgidus To be Published 0 0 0 0
3IC4 The crystal structure of the glutaredoxin(grx-1) from Archaeoglobus fulgidus 2009-07-17 2009-08-18 Zhang, R.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. The crystal structure of the glutaredoxin from Archaeoglobus fulgidus To be Published 0 0 0 0
3IH6 Crystal structure of putative zinc protease from Bordetella pertussis Tohama I 2009-07-29 2009-08-18 Chang, C.,Chhor, G.,Bearden, J.,Joachimiak, A. Crystal structure of putative zinc protease from Bordetella pertussis Tohama I To be Published 0 0 0 0
3III 1.95 Angstrom Crystal Structure of CocE/NonD family hydrolase (SACOL2612) from Staphylococcus aureus 2009-08-01 2009-08-18 Osinski, T.,Chruszcz, M.,Domagalski, M.J.,Cymborowski, M.,Shumilin, I.A.,Skarina, T.,Onopriyenko, O.,Zimmerman, M.D.,Savchenko, A.,Edwards, A.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) 1.95 Angstrom Crystal Structure of CocE/NonD family hydrolase (SACOL2612) from Staphylococcus aureus To be Published 0 0 0 0
3IBS Crystal structure of conserved hypothetical protein BatB from Bacteroides thetaiotaomicron 2009-07-16 2009-08-25 Hattne, J.,Bearden, J.,Borek, D.,Nakka, C.,Sather, A.,Joachimiak, A.,Otwinowski, Z. Crystal structure of conserved hypothetical protein BatB from Bacteroides thetaiotaomicron To be Published 0 0 0 0
3IG3 19717441 Crystal structure of mouse Plexin A3 intracellular domain 2009-07-27 2009-08-25 He, H.,Yang, T.,Terman, J.R.,Zhang, X. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. Proc.Natl.Acad.Sci.USA 2009 106 15610 15615
3IG3 19717441 Crystal structure of mouse Plexin A3 intracellular domain 2009-07-27 2009-08-25 He, H.,Yang, T.,Terman, J.R.,Zhang, X. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. Proc.Natl.Acad.Sci.USA 2009 106 15610 15615
3F00 Crystal Structure of Synaptotagmin I C2A domain with Cu(II) 2008-10-24 2009-09-08 Guo, F.,Dakshinamurthy, R.,Thallapuranam, S.K.K.,Sakon, J. Crystal structure of Synaptotagmin I C2A To be Published 0 0 0 0
3F04 Crystal Structure of Synaptotagmin I C2A domain 2008-10-24 2009-09-08 Guo, F.,Dakshinamurthy, R.,Thallapuranam, S.K.K.,Sakon, J. Cystal structure of synaptotagmin I C2A to be published 0 0 0 0
3IV8 N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate 2009-08-31 2009-09-08 Osipiuk, J.,Maltseva, N.,Stam, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate. To be Published 0 0 0 0
3IJM The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. 2009-08-04 2009-09-22 Cuff, M.E.,Tesar, C.,Samano, S.,Bearden, J.,Joachimiak, A. The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. TO BE PUBLISHED 0 0 0 0
3IX7 Crystal structure of a domain of functionally unknown protein from Thermus thermophilus HB8 2009-09-03 2009-09-22 Chang, C.,Li, H.,Clancy, S.,Joachimiak, A. Crystal structure of a domain of functionally unknown protein from Thermus thermophilus HB8 To be Published 0 0 0 0
3JSA Homoserine dehydrogenase from Thermoplasma volcanium complexed with NAD 2009-09-09 2009-09-22 Osipiuk, J.,Nocek, B.,Hendricks, R.,Abdullah, J.,Joachimiak, A. X-ray crystal structure of Homoserine dehydrogenase from Thermoplasma volcanium To be Published 0 0 0 0
3JU1 Crystal Structure of Enoyl-CoA Hydratase/Isomerase Family Protein 2009-09-14 2009-09-22 Kim, Y.,Xu, X.,Cui, H.,Ng, J.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal Structure of Enoyl-CoA Hydratase/Isomerase Family Protein To be Published 0 0 0 0
3JU8 Crystal Structure of Succinylglutamic Semialdehyde Dehydrogenase from Pseudomonas aeruginosa. 2009-09-14 2009-09-22 Kim, Y.,Li, H.,Buck, K.,Joachimiak, A. Crystal Structure of Succinylglutamic Semialdehyde Dehydrogenase from Pseudomonas aeruginosa To be Published 0 0 0 0
3JUW Putative GnaT-family acetyltransferase from Bordetella pertussis. 2009-09-15 2009-09-22 Osipiuk, J.,Wu, R.,Cobb, G.,Joachimiak, A. X-ray crystal structure of putative GnaT-family acetyltransferase from Bordetella pertussis. To be Published 0 0 0 0
3HTX 19812675 Crystal structure of small RNA methyltransferase HEN1 2009-06-12 2009-09-29 Huang, Y.,Ji, L.,Huang, Q.,Vassylyev, D.G.,Chen, X.,Ma, J.B. Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature 2009 461 823 827
3JYF The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 2009-09-21 2009-09-29 Fan, Y.,Volkart, L.,Cobb, G.,Joachimiak, A. The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 To be Published 0 0 0 0
3F05 Crystal Structure of Synaptotagmin I C2A domain with Mn(II) 2008-10-24 2009-10-06 Guo, F.,Dakshinamurthy, R.,Thallapuranam, S.K.K.,Sakon, J. Cystal structure of synaptotagmin I C2A to be published 0 0 0 0
3FP0 19319932 Structural and Functional Characterization of TRI3 Trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides 2009-01-02 2009-10-13 Garvey, G.S.,McCormick, S.P.,Alexander, N.J.,Rayment, I. Structural and functional characterization of TRI3 trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides Protein Sci. 2009 18 747 761
3GZP 19800308 HUMAN SOD1 G93A Metal-free Variant 2009-04-07 2009-10-13 Galaleldeen, A.,Strange, R.W.,Whitson, L.J.,Antonyuk, S.V.,Narayana, N.,Taylor, A.B.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J. Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Arch.Biochem.Biophys. 2009 492 40 47
3IJW 21601576 Crystal structure of BA2930 in complex with CoA 2009-08-05 2009-10-13 Klimecka, M.M.,Chruszcz, M.,Font, J.,Skarina, T.,Shumilin, I.,Onopryienko, O.,Porebski, P.J.,Cymborowski, M.,Zimmerman, M.D.,Hasseman, J.,Glomski, I.J.,Lebioda, L.,Savchenko, A.,Edwards, A.,Minor, W. Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol. 2011 410 411 423
3JR7 The crystal structure of the protein of DegV family COG1307 with unknown function from Ruminococcus gnavus ATCC 29149 2009-09-08 2009-10-20 Zhang, R.,Hatzos, C.,Clancy, S.,Joachimiak, A. The crystal structure of the protein of DegV family COG1307 with unknown function from Ruminococcus gnavus ATCC 29149 To be Published 0 0 0 0
3FA9 Crystal structure of the apo R132K:Y134F:R111L:L121D mutant of cellular retinoic acid-binding protein II at 1.94 angstrom resolution 2008-11-16 2009-10-27 Jia, X.,Lee, K.S.,Vasileiou, C.,Borhan, B.,Geiger, J.H. Crystal structures of apo cellular retinoic acid-binding protein II mutants: Structural integrity investigated through multiple site mutations To be Published 0 0 0 0
3K6C Crystal structure of protein ne0167 from nitrosomonas europaea 2009-10-08 2009-10-27 Chang, C.,Evdokimova, E.,Savchenko, A.,Edwards, A.M.,Joachimiak, A. Crystal Structure of Protein Ne0167 from Nitrosomonas Europaea To be Published 0 0 0 0
3IK3 19878872 AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance 2009-08-05 2009-11-03 O'Hare, T.,Shakespeare, W.C.,Zhu, X.,Eide, C.A.,Rivera, V.M.,Wang, F.,Adrian, L.T.,Zhou, T.,Huang, W.S.,Xu, Q.,Metcalf, C.A.,Tyner, J.W.,Loriaux, M.M.,Corbin, A.S.,Wardwell, S.,Ning, Y.,Keats, J.A.,Wang, Y.,Sundaramoorthi, R.,Thomas, M.,Zhou, D.,Snodgrass, J.,Commodore, L.,Sawyer, T.K.,Dalgarno, D.C.,Deininger, M.W.,Druker, B.J.,Clackson, T. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell 2009 16 401 412
3KK4 uncharacterized protein BP1543 from Bordetella pertussis Tohama I 2009-11-04 2009-11-17 Chang, C.,Chhor, G.,Cobb, G.,Joachimiak, A. Crystal structure of uncharacterized protein BP1543 from Bordetella pertussis Tohama I To be Published 0 0 0 0
3K7R 19965379 Crystal structure of [TM][CuAtx1]3 2009-10-13 2009-11-24 Alvarez, H.M.,Xue, Y.,Robinson, C.D.,Canalizo-Hernandez, M.A.,Marvin, R.G.,Kelly, R.A.,Mondragon, A.,Penner-Hahn, J.E.,O'Halloran, T.V. Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation. Science 2010 327 331 334
3KKW 25044180 Crystal structure of His-tagged form of PA4794 protein 2009-11-06 2009-11-24 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments. Protein Sci. 2014 23 1359 1368
3KD8 Cofactor-Independent Phosphoglycerate mutase from Thermoplasma Acidophilum DSM 1728 2009-10-22 2009-12-01 Joachimiak, A.,Duke, N.E.C.,Marshall, N.,Buck, K. Cofactor-Independent Phosphoglycerate mutase from Thermoplasma Acidophilum DSM 1728 To be Published 0 0 0 0
3KN3 Crystal Structure of LysR Substrate Binding Domain (25-263) of Putative Periplasmic Protein from Wolinella succinogenes 2009-11-11 2009-12-01 Kim, Y.,Volkart, L.,Bearden, J.,Joachimiak, A. Crystal Structure of LysR Substrate Binding Domain from Wolinella succinogenes To be Published 0 0 0 0
3KTB Crystal Structure of Arsenical Resistance Operon Trans-acting Repressor from Bacteroides vulgatus ATCC 8482 2009-11-24 2009-12-08 Kim, Y.,Tesar, C.,Feldmann, B.,Joachimiak, A. Crystal Structure of Arsenical Resistance Operon Trans-acting Repressor from Bacteroides vulgatus ATCC 8482 To be Published 0 0 0 0
3KWP Crystal structure of putative methyltransferase from Lactobacillus brevis 2009-12-01 2009-12-15 Chang, C.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of putative methyltransferase from Lactobacillus brevis To be Published 0 0 0 0
3KWP Crystal structure of putative methyltransferase from Lactobacillus brevis 2009-12-01 2009-12-15 Chang, C.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of putative methyltransferase from Lactobacillus brevis To be Published 0 0 0 0
3FSS 22307274 Structure of the tandem PH domains of Rtt106 2009-01-11 2009-12-22 Su, D.,Hu, Q.,Li, Q.,Thompson, J.R.,Cui, G.,Fazly, A.,Davies, B.A.,Botuyan, M.V.,Zhang, Z.,Mer, G. Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature 2012 483 104 107
3JW4 The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum 2009-09-17 2009-12-22 Cuff, M.E.,Bigelow, L.,Moy, S.,Joachimiak, A. The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum TO BE PUBLISHED 0 0 0 0
3KV1 Crystal Structure of Putative Sugar-Binding Domain of Transcriptional Repressor from Vibrio fischeri 2009-11-28 2009-12-22 Kim, Y.,Marshall, N.,Bearden, J.,Joachimiak, A. Crystal Structure of Putative Sugar-Binding Domain of Transcriptional Repressor from Vibrio fischeri To be Published 0 0 0 0
3KZL 21601576 Crystal structure of BA2930 mutant (H183G) in complex with AcCoA 2009-12-08 2009-12-22 Klimecka, M.M.,Chruszcz, M.,Font, J.,Skarina, T.,Shumilin, I.,Onopryienko, O.,Porebski, P.J.,Cymborowski, M.,Zimmerman, M.D.,Hasseman, J.,Glomski, I.J.,Lebioda, L.,Savchenko, A.,Edwards, A.,Minor, W. Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol. 2011 410 411 423
3H33 19857457 PpcC, A cytochrome c7 from Geobacter sulfurreducens 2009-04-15 2009-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Yang, X.,Duke, N.E.,Erickson, J.,Orshonsky, V.,Johnson, G.,Schiffer, M. Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens. Biochim.Biophys.Acta 2010 1797 222 232
3H34 19857457 PpcE, A cytochrome c7 from Geobacter sulfurreducens 2009-04-15 2009-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Yang, X.,Duke, N.E.,Erickson, J.,Orshonsky, V.,Johnson, G.,Schiffer, M. Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens. Biochim.Biophys.Acta 2010 1797 222 232
3H4N 19857457 PpcD, A cytochrome c7 from Geobacter sulfurreducens 2009-04-20 2009-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Yang, X.,Duke, N.E.,Erickson, J.,Orshonsky, V.,Johnson, G.,Schiffer, M. Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens. Biochim.Biophys.Acta 2010 1797 222 232
3KNW Crystal structure of a putative transcriptional regulator (TetR/AcrR family member) from putative transcriptional regulator (TetR/AcrR family) 2009-11-12 2010-01-05 Nocek, B.,Bigelow, L.,Cobb, G.,Joachimiak, A. Crystal structure of a putative transcriptional regulator (TetR/AcrR family member) from putative transcriptional regulator (TetR/AcrR family) To be Published 0 0 0 0
3KRV The Structure Of Potential Metal-Dependent Hydrolase With Cyclase Activity 2009-11-19 2010-01-05 Rezacova, P.,Rakonjac, N.,Maderova, J.,Borek, D.,Tomchick, D.,Joachimiak, A.,Collart, F.,Otwinowski, Z. The Structure Of Potential Metal-Dependent Hydrolase With Cyclase Activity To be Published 0 0 0 0
3KWM Crystal structure of ribose-5-isomerase A 2009-12-01 2010-01-05 0 0 0 0
3H7B 20064447 Human Class I MHC HLA-A2 in complex with the Tel1p peptide 2009-04-24 2010-01-12 Borbulevych, O.Y.,Piepenbrink, K.H.,Gloor, B.E.,Scott, D.R.,Sommese, R.F.,Cole, D.K.,Sewell, A.K.,Baker, B.M. T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity 2009 31 885 896
3H7W 19950993 Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS017 2009-04-28 2010-01-12 Key, J.,Scheuermann, T.H.,Anderson, P.C.,Daggett, V.,Gardner, K.H. Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc. 2009 131 17647 17654
3H82 19950993 Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS020 2009-04-28 2010-01-12 Key, J.,Scheuermann, T.H.,Anderson, P.C.,Daggett, V.,Gardner, K.H. Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc. 2009 131 17647 17654
3H9S 20064447 The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide 2009-04-30 2010-01-12 Borbulevych, O.Y.,Piepenbrink, K.H.,Gloor, B.E.,Scott, D.R.,Sommese, R.F.,Cole, D.K.,Sewell, A.K.,Baker, B.M. T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity 2009 31 885 896
3HAF 19927125 Human prion protein variant V129 domain swapped dimer 2009-05-01 2010-01-12 Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J. 2010 29 251 262
3HJX 19927125 Human prion protein variant D178N with V129 2009-05-22 2010-01-12 Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J. 2010 29 251 262
3ICY The crystal structure of sensory box histidine kinase/response regulator domain from Chlorobium tepidum TLS 2009-07-19 2010-01-12 Ruiying, W.,Shonda, C.,Joachimiak, A. The crystal structure of sensory box histidine kinase/response regulator domain from Chlorobium To be Published 0 0 0 0
3IU7 20038112 M. tuberculosis methionine aminopeptidase with Mn inhibitor A02 2009-08-30 2010-01-12 Lu, J.P.,Chai, S.C.,Ye, Q.Z. Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem. 2010 53 1329 1337
3IU8 20038112 M. tuberculosis methionine aminopeptidase with Ni inhibitor T03 2009-08-30 2010-01-12 Lu, J.P.,Chai, S.C.,Ye, Q.Z. Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem. 2010 53 1329 1337
3IU9 20038112 M. tuberculosis methionine aminopeptidase with Ni inhibitor T07 2009-08-30 2010-01-12 Lu, J.P.,Chai, S.C.,Ye, Q.Z. Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem. 2010 53 1329 1337
3K2N The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium Tepidum TLS 2009-09-30 2010-01-19 Wu, R.,Clancy, S.,Joachimiak, A. The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium To be Published 0 0 0 0
3KWO Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni 2009-12-01 2010-01-19 Kim, Y.,Gu, M.,Papazisi, L.,Anderson, W.,Joachimiak, A. Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni To be Published 0 0 0 0
3L93 Phosphopantetheine adenylyltransferase from Yersinia pestis. 2010-01-04 2010-01-19 Osipiuk, J.,Maltseva, N.,Makowska-grzyska, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of phosphopantetheine adenylyltransferase from Yersinia pestis. To be Published 0 0 0 0
3LAO Crystal Structure of Enoyl-CoA Hydratase from Pseudomonas aeruginosa PA01 2010-01-06 2010-01-19 Kim, Y.,Chhor, G.,Buck, K.,Joachimiak, A. Crystal Structure of Enoyl-CoA Hydratase from Pseudomonas aeruginosa PA01 To be Published 0 0 0 0
3KTZ 19913503 Structure of GAP31 2009-11-26 2010-01-26 Li, H.G.,Huang, P.L.,Zhang, D.,Sun, Y.,Chen, H.C.,Zhang, J.,Huang, P.L.,Kong, X.P.,Lee-Huang, S. A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun. 2010 391 340 345
3KU0 19913503 Structure of GAP31 with adenine at its binding pocket 2009-11-26 2010-01-26 Li, H.G.,Huang, P.L.,Zhang, D.,Sun, Y.,Chen, H.C.,Zhang, J.,Huang, P.L.,Kong, X.P.,Lee-Huang, S. A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun. 2010 391 340 345
3LED Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase III from Rhodopseudomonas palustris CGA009 2010-01-14 2010-01-26 Chang, C.,Xu, X.,Cui, H.,Chin, S.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase III from Rhodopseudomonas palustris CGA009 To be Published 0 0 0 0
3KZQ The crystal structure of the protein with unknown function from Vibrio parahaemolyticus RIMD 2210633 2009-12-08 2010-02-02 Zhang, R.,Weger, A.,Shackelford, G.,Joachimiak, A. The crystal structure of the protein with unknown function from Vibrio parahaemolyticus RIMD 2210633 To be Published 0 0 0 0
3LHE The crystal structure of the C-terminal domain of a GntR family transcriptional regulator from Bacillus anthracis str. Sterne 2010-01-22 2010-02-02 Tan, K.,Chhor, G.,Clancy, S.,Joachimiak, A. The crystal structure of the C-terminal domain of a GntR family transcriptional regulator from Bacillus anthracis str. Sterne To be Published 0 0 0 0
3LNP 23877221 Crystal Structure of Amidohydrolase family Protein OLEI01672_1_465 from Oleispira antarctica 2010-02-02 2010-02-16 Kube, M.,Chernikova, T.N.,Al-Ramahi, Y.,Beloqui, A.,Lopez-Cortez, N.,Guazzaroni, M.E.,Heipieper, H.J.,Klages, S.,Kotsyurbenko, O.R.,Langer, I.,Nechitaylo, T.Y.,Lunsdorf, H.,Fernandez, M.,Juarez, S.,Ciordia, S.,Singer, A.,Kagan, O.,Egorova, O.,Petit, P.A.,Stogios, P.,Kim, Y.,Tchigvintsev, A.,Flick, R.,Denaro, R.,Genovese, M.,Albar, J.P.,Reva, O.N.,Martinez-Gomariz, M.,Tran, H.,Ferrer, M.,Savchenko, A.,Yakunin, A.F.,Yakimov, M.M.,Golyshina, O.V.,Reinhardt, R.,Golyshin, P.N. Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun 2013 4 2156 2156
3LOF C-terminal domain of human heat shock 70kDa protein 1B. 2010-02-03 2010-02-16 Osipiuk, J.,Gu, M.,Mihelic, M.,Orton, K.,Morimoto, R.I.,Joachimiak, A. X-ray crystal structure of C-terminal domain of human heat shock 70kDa protein 1B. To be Published 0 0 0 0
3LOQ The crystal structure of a universal stress protein from Archaeoglobus fulgidus DSM 4304 2010-02-04 2010-02-16 Tan, K.,Weger, A.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of a universal stress protein from Archaeoglobus fulgidus DSM 4304 To be Published 0 0 0 0
3LM7 Crystal Structure of DUF1341 representative, from Yersinia enterocolitica subsp. enterocolitica 8081 2010-01-29 2010-02-23 Joachimiak, A.,Duke, N.E.C.,Feldmann, B.,Wu, R. Crystal Structure of DUF1341 representative, from Yersinia enterocolitica subsp. enterocolitica 8081 To be Published 0 0 0 0
3LQN Crystal Structure of CBS Domain-containing Protein of Unknown Function from Bacillus anthracis str. Ames Ancestor 2010-02-09 2010-03-02 Kim, Y.,Mulligan, R.,Hasseman, J.,Anderson, W.F.,Joachimiak, A. Crystal Structure of CBS Domain-containing Protein of Unknown Function from Bacillus anthracis str. Ames Ancestor To be Published 0 0 0 0
3LQ9 20166753 Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR 2010-02-08 2010-03-09 Vega-Rubin-de-Celis, S.,Abdallah, Z.,Kinch, L.,Grishin, N.V.,Brugarolas, J.,Zhang, X. Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry 2010 49 2491 2501
3LQ9 20166753 Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR 2010-02-08 2010-03-09 Vega-Rubin-de-Celis, S.,Abdallah, Z.,Kinch, L.,Grishin, N.V.,Brugarolas, J.,Zhang, X. Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry 2010 49 2491 2501
3LVY Crystal Structure of Carboxymuconolactone Decarboxylase Family Protein SMU.961 from Streptococcus mutans 2010-02-22 2010-03-09 Kim, Y.,Xu, X.,Cui, H.,Chin, S.,Edwards, A.,Savchenko, A.,Joachimiak, A. Crystal Structure of Carboxymuconolactone Decarboxylase Family Protein SMU.961 from Streptococcus mutans To be Published 0 0 0 0
3LYD Crystal structure of Putative uncharacterized protein from Jonesia denitrificans 2010-02-26 2010-03-09 Chang, C.,Volkart, L.,Bearden, J.,Wu, D.,Eisen, J.,Kerfeld, C.,Joachimiak, A. Crystal structure of Putative uncharacterized protein from Jonesia denitrificans To be Published 0 0 0 0
3A3K 20066666 Reversibly bound chloride in the atrial natriuretic peptide receptor hormone-binding domain 2009-06-14 2010-03-16 Ogawa, H.,Qiu, Y.,Philo, J.S.,Arakawa, T.,Ogata, C.M.,Misono, K.S. Reversibly bound chloride in the atrial natriuretic peptide receptor hormone-binding domain: Possible allosteric regulation and a conserved structural motif for the chloride-binding site. Protein Sci. 2010 19 544 557
3LJK Glucose-6-phosphate isomerase from Francisella tularensis. 2010-01-26 2010-03-16 Osipiuk, J.,Maltseva, N.,Hasseman, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of glucose-6-phosphate isomerase from Francisella tularensis. To be Published 0 0 0 0
3LNL 17187687 Crystal structure of Staphylococcus aureus protein SA1388 2010-02-02 2010-03-16 Singh Saikatendu, K.,Zhang, X.,Kinch, L.,Leybourne, M.,Grishin, N.V.,Zhang, H. Structure of a Conserved Hypothetical Protein Sa1388 from S. aureus Reveals a Capped Hexameric Toroid with Two Pii Domain Lids and a Dinuclear Metal Center. Bmc Struct.Biol. 2006 6 27 0
3LOC Crystal structure of putative transcriptional regulator ycdc 2010-02-03 2010-03-16 Patskovsky, Y.V.,Mennella, V.,Almo, S.C. Crystal Structure of Hypothetical Transcriptional Regulator Ycdc from Escherichia Coli To be Published 0 0 0 0
3LOD The crystal structure of the putative acyl-CoA N-acyltransferase from Klebsiella pneumoniae subsp.pneumoniae MGH 78578 2010-02-03 2010-03-16 Zhang, R.,Volkart, L.,Bearden, J.,Joachimiak, A. The crystal structure of the putative acyl-CoA N-acyltransferase from Klebsiella pneumoniae To be Published 0 0 0 0
3M1R The crystal structure of formimidoylglutamase from Bacillus subtilis subsp. subtilis str. 168 2010-03-05 2010-03-16 Tan, K.,Bigelow, L.,Buck, K.,Joachimiak, A. The crystal structure of formimidoylglutamase from Bacillus subtilis subsp. subtilis str. 168 To be Published 0 0 0 0
3M5P Glucose-6-phosphate isomerase from Francisella tularensis complexed with fructose-6-phosphate. 2010-03-12 2010-03-23 Osipiuk, J.,Maltseva, N.,Hasseman, J.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of glucose-6-phosphate isomerase from Francisella tularensis complexed with fructose-6-phosphate. To be Published 0 0 0 0
3M33 The crystal structure of a functionally unknown protein from Deinococcus radiodurans R1 2010-03-08 2010-03-31 Tan, K.,Mack, J.,Feldmann, B.,Joachimiak, A. The crystal structure of a functionally unknown protein from Deinococcus radiodurans R1 To be Published 0 0 0 0
3L15 20368466 Human Tead2 transcriptional factor 2009-12-10 2010-04-07 Tian, W.,Yu, J.,Tomchick, D.R.,Pan, D.,Luo, X. Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc.Natl.Acad.Sci.USA 2010 107 7293 7298
3L9A Structure of the C-terminal domain from a Streptococcus mutans hypothetical 2010-01-04 2010-04-07 Singer, A.U.,Cuff, M.E.,Xu, X.,Cui, H.,Edwards, A.M.,Savchenko, A. Structure of the C-terminal domain from a Streptococcus mutans hypothetical To be Published 0 0 0 0
3M49 Crystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracis 2010-03-10 2010-04-07 Maltseva, N.,Kim, Y.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracis To be Published 0 0 0 0
3M5U Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuni 2010-03-13 2010-04-07 Kim, Y.,Gu, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuni To be Published 0 0 0 0
3M4R Structure of the N-terminal Class II Aldolase domain of a conserved protein from Thermoplasma acidophilum 2010-03-11 2010-04-14 Cuff, M.E.,Li, H.,Clancy, S.,Joachimiak, A. Structure of the N-terminal Class II Aldolase domain of a conserved protein from Thermoplasma acidophilum TO BE PUBLISHED 0 0 0 0
3L6X 20371349 Crystal structure of p120 catenin in complex with E-cadherin 2009-12-27 2010-04-21 Ishiyama, N.,Lee, S.H.,Liu, S.,Li, G.Y.,Smith, M.J.,Reichardt, L.F.,Ikura, M. Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.) 2010 141 117 128
3L6Y 20371349 Crystal structure of p120 catenin in complex with E-cadherin 2009-12-27 2010-04-21 Ishiyama, N.,Lee, S.H.,Liu, S.,Li, G.Y.,Smith, M.J.,Reichardt, L.F.,Ikura, M. Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.) 2010 141 117 128
3KZ1 20430886 Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA 2009-12-07 2010-04-28 Chen, Z.,Medina, F.,Liu, M.Y.,Thomas, C.,Sprang, S.R.,Sternweis, P.C. Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation. J.Biol.Chem. 2010 285 21070 21081
3L1X 20696396 Crystal Structure of U-box Domain of Human E4B Ubiquitin Ligase 2009-12-14 2010-05-05 Benirschke, R.C.,Thompson, J.R.,Nomine, Y.,Wasielewski, E.,Juranic, N.,Macura, S.,Hatakeyama, S.,Nakayama, K.I.,Botuyan, M.V.,Mer, G. Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure 2010 18 955 965
3L1Z 20696396 Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme 2009-12-14 2010-05-05 Benirschke, R.C.,Thompson, J.R.,Nomine, Y.,Wasielewski, E.,Juranic, N.,Macura, S.,Hatakeyama, S.,Nakayama, K.I.,Botuyan, M.V.,Mer, G. Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure 2010 18 955 965
3MN2 The crystal structure of a probable AraC family transcriptional regulator from Rhodopseudomonas palustris CGA009 2010-04-20 2010-05-12 Tan, K.,Li, H.,Buck, K.,Joachimiak, A. The crystal structure of a probable AraC family transcriptional regulator from Rhodopseudomonas palustris CGA009 To be Published 0 0 0 0
3MQG 20433200 crystal structure of the 3-N-acetyl transferase WlbB from Bordetella petrii in complex with acetyl-CoA 2010-04-28 2010-05-12 Thoden, J.B.,Holden, H.M. Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . Biochemistry 2010 49 4644 4653
3MQH 20433200 crystal structure of the 3-N-acetyl transferase WlbB from Bordetella petrii in complex with CoA and UDP-3-amino-2-acetamido-2,3-dideoxy glucuronic acid 2010-04-28 2010-05-12 Thoden, J.B.,Holden, H.M. Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . Biochemistry 2010 49 4644 4653
3MFD The Structure of the Beta-lactamase superfamily domain of D-alanyl-D-alanine carboxypeptidase from Bacillus subtilis 2010-04-01 2010-05-19 Cuff, M.E.,Rakowski, E.,Buck, K.,Joachimiak, A. The Structure of the Beta-lactamase superfamily domain of D-alanyl-D-alanine carboxypeptidase from Bacillus subtilis. TO BE PUBLISHED 0 0 0 0
3MLE 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori cocrystallized with ATP 2010-04-16 2010-05-19 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3MJF Phosphoribosylamine-glycine ligase from Yersinia pestis 2010-04-12 2010-05-26 Osipiuk, J.,Zhou, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. X-ray crystal structure of phosphoribosylamine-glycine ligase from Yersinia pestis. To be Published 0 0 0 0
3MUE Crystal Structure of Pantoate-beta-Alanine Ligase from Salmonella typhimurium 2010-05-03 2010-05-26 Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Pantoate-beta-Alanine Ligase from Salmonella typhimurium To be Published 0 0 0 0
3N0M 21601576 Crystal structure of BA2930 mutant (H183G) in complex with AcCoA 2010-05-14 2010-06-09 Klimecka, M.M.,Chruszcz, M.,Font, J.,Skarina, T.,Shumilin, I.,Onopryienko, O.,Porebski, P.J.,Cymborowski, M.,Zimmerman, M.D.,Hasseman, J.,Glomski, I.J.,Lebioda, L.,Savchenko, A.,Edwards, A.,Minor, W. Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol. 2011 410 411 423
3MXT Crystal Structure of Pantoate-Beta-alanine Ligase from Campylobacter jejuni 2010-05-07 2010-06-16 Kim, Y.,Zhou, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Pantoate-Beta-alanine Ligase from Campylobacter jejuni To be Published 0 0 0 0
3N3T 20691189 Crystal structure of putative diguanylate cyclase/phosphodiesterase complex with cyclic di-gmp 2010-05-20 2010-06-16 Tchigvintsev, A.,Xu, X.,Singer, A.,Chang, C.,Brown, G.,Proudfoot, M.,Cui, H.,Flick, R.,Anderson, W.F.,Joachimiak, A.,Galperin, M.Y.,Savchenko, A.,Yakunin, A.F. Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J.Mol.Biol. 2010 402 524 538
3HPJ 20619457 Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide 2009-06-04 2010-06-23 Borbulevych, O.Y.,Do, P.,Baker, B.M. Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics. Mol.Immunol. 2010 47 2519 2524
3M16 23877221 Structure of a Transaldolase from Oleispira antarctica 2010-03-04 2010-06-23 Kube, M.,Chernikova, T.N.,Al-Ramahi, Y.,Beloqui, A.,Lopez-Cortez, N.,Guazzaroni, M.E.,Heipieper, H.J.,Klages, S.,Kotsyurbenko, O.R.,Langer, I.,Nechitaylo, T.Y.,Lunsdorf, H.,Fernandez, M.,Juarez, S.,Ciordia, S.,Singer, A.,Kagan, O.,Egorova, O.,Alain Petit, P.,Stogios, P.,Kim, Y.,Tchigvintsev, A.,Flick, R.,Denaro, R.,Genovese, M.,Albar, J.P.,Reva, O.N.,Martinez-Gomariz, M.,Tran, H.,Ferrer, M.,Savchenko, A.,Yakunin, A.F.,Yakimov, M.M.,Golyshina, O.V.,Reinhardt, R.,Golyshin, P.N. Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun 2013 4 2156 2156
3MQZ Crystal Structure of Conserved Protein DUF1054 from Pink Subaerial Biofilm Microbial Leptospirillum sp. Group II UBA. 2010-04-28 2010-06-23 Kim, Y.,Xu, X.,Cui, H.,Chin, S.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crystal Structure of Conserved Protein DUF1054 from Pink Subaerial Biofilm Microbial Leptospirillum sp. Group II UBA. To be Published 0 0 0 0
3MR0 Crystal Structure of Sensory Box Histidine Kinase/Response Regulator from Burkholderia thailandensis E264 2010-04-28 2010-06-23 Kim, Y.,Tesar, C.,Buck, K.,Joachimiak, A. Crystal Structure of Sensory Box Histidine Kinase/Response Regulator from Burkholderia thailandensis E264 To be Published 0 0 0 0
3MTU 20465283 Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle 2010-04-30 2010-06-23 Frye, J.,Klenchin, V.A.,Rayment, I. Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition . Biochemistry 2010 49 4908 4920
3MUD 20465283 Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle 2010-05-02 2010-06-23 Frye, J.,Klenchin, V.A.,Rayment, I. Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition . Biochemistry 2010 49 4908 4920
3NJF 22493430 Y26F mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis 2010-06-17 2010-07-07 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3M84 Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis 2010-03-17 2010-07-14 Maltseva, N.,Kim, Y.,Hasseman, J.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis To be Published 0 0 0 0
3NJG 22493430 K98A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis. 2010-06-17 2010-07-14 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3NJJ 22493430 P115A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis 2010-06-17 2010-07-21 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3NJK 22493430 D116A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis, at pH5.5 2010-06-17 2010-07-21 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3NJL 22493430 D116A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis, at pH7.5 2010-06-17 2010-07-21 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3NJM 22493430 P117A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis. 2010-06-17 2010-07-21 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3NJN 22493430 Q118A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis 2010-06-17 2010-07-21 Osipiuk, J.,Mulligan, R.,Bargassa, M.,Hamilton, J.E.,Cunningham, M.A.,Joachimiak, A. Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J.Biol.Chem. 2012 287 19452 19461
3MLA 20578699 BaNadD in complex with inhibitor 1_02 2010-04-16 2010-07-28 Huang, N.,Kolhatkar, R.,Eyobo, Y.,Sorci, L.,Rodionova, I.,Osterman, A.L.,Mackerell, A.D.,Zhang, H. Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement. J.Med.Chem. 2010 53 5229 5239
3NA2 Crystal Structure of Protein of Unknown Function from Mine Drainage Metagenome Leptospirillum rubarum 2010-05-31 2010-07-28 Kim, Y.,Xu, X.,Cui, H.,Chin, S.,Savchenko, A.,Edwards, A.,Joachimiak, A. Crsystal Structure of Protein of Unknown Function from Mine Drainage Metagenome Leptospirillum rubarum To be Published 0 0 0 0
3NYU 28028852 X-ray crystal structure of the Wbpe (WlbE) aminotransferase from pseudomonas aeruginosa as the PLP internal aldimine adduct with lysine 185 2010-07-15 2010-07-28 Dow, G.T.,Gilbert, M.,Thoden, J.B.,Holden, H.M. Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci. 2017 26 586 599
3NXK Crystal Structure of Probable Cytoplasmic L-asparaginase from Campylobacter jejuni 2010-07-14 2010-08-04 Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Probable Cytoplasmic L-asparaginase from Campylobacter jejuni To be Published 0 0 0 0
3O5X 20170098 Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor 2010-07-28 2010-08-11 Zhang, X.,He, Y.,Liu, S.,Yu, Z.,Jiang, Z.X.,Yang, Z.,Dong, Y.,Nabinger, S.C.,Wu, L.,Gunawan, A.M.,Wang, L.,Chan, R.J.,Zhang, Z.Y. Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J.Med.Chem. 2010 53 2482 2493
3K3R 20703307 Unrefined crystal structure of a LexA-DNA complex 2009-10-04 2010-08-18 Zhang, A.P.,Pigli, Y.Z.,Rice, P.A. Structure of the LexA-DNA complex and implications for SOS box measurement. Nature 2010 466 883 886
3O9Z 20690587 Crystal structure of the WlbA (WbpB) dehydrogenase from Thermus thermophilus in complex with NAD and alpha-ketoglutarate at 1.45 angstrom resolution 2010-08-04 2010-08-18 Thoden, J.B.,Holden, H.M. Structural and Functional Studies of WlbA: A Dehydrogenase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid . Biochemistry 2010 49 7939 7948
3OA0 20690587 Crystal structure of the WlbA (WbpB) Dehydrogenase from Thermus thermophilus in complex with NAD and UDP-GlcNAcA 2010-08-04 2010-08-18 Thoden, J.B.,Holden, H.M. Structural and Functional Studies of WlbA: A Dehydrogenase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid . Biochemistry 2010 49 7939 7948
3OA2 20690587 Crystal structure of the WlbA (WbpB) dehydrogenase from Pseudomonas aeruginosa in complex with NAD at 1.5 angstrom resolution 2010-08-04 2010-08-18 Thoden, J.B.,Holden, H.M. Structural and Functional Studies of WlbA: A Dehydrogenase Involved in the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid . Biochemistry 2010 49 7939 7948
3IKL 19837034 Crystal structure of Pol gB delta-I4. 2009-08-06 2010-08-25 Lee, Y.S.,Kennedy, W.D.,Yin, Y.W. Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Cell(Cambridge,Mass.) 2009 139 312 324
3OD1 The crystal structure of an ATP phosphoribosyltransferase regulatory subunit/histidyl-tRNA synthetase from Bacillus halodurans C 2010-08-10 2010-08-25 Tan, K.,Bigelow, L.,Hamilton, J.,Bearden, J.,Joachimiak, A. The crystal structure of aATP phosphoribosyltransferase regulatory subunit/histidyl-tRNA synthetase from Bacillus halodurans C To be Published 0 0 0 0
3NBM The lactose-specific IIB component domain structure of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) from Streptococcus pneumoniae. 2010-06-03 2010-09-08 Cuff, M.E.,Chhor, G.,Clancy, S.,Joachimiak, A. Structure of the lactose-specific IIB component domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) from Streptococcus pneumoniae. TO BE PUBLISHED 0 0 0 0
3OMS Putative 3-demethylubiquinone-9 3-methyltransferase, PhnB protein, from Bacillus cereus. 2010-08-27 2010-09-08 Osipiuk, J.,Li, H.,Abdullah, J.,Joachimiak, A. X-ray crystal structure of putative 3-demethylubiquinone-9 3-methyltransferase, PhnB protein, from Bacillus cereus. To be Published 0 0 0 0
3ONO Crystal Structure of Ribose-5-phosphate Isomerase LacAB_rpiB from Vibrio parahaemolyticus 2010-08-30 2010-09-08 Kim, Y.,Volkart, L.,Abdullah, J.,Joachimiak, A. Crystal Structure of Ribose-5-phosphate Isomerase LacAB_rpiB from Vibrio parahaemolyticus To be Published 0 0 0 0
3ONQ Crystal Structure of Regulator of Polyketide Synthase Expression BAD_0249 from Bifidobacterium adolescentis 2010-08-30 2010-09-08 Kim, Y.,Wu, R.,Tan, K.,Morales, J.,Bearden, J.,Joachimiak, A. Crystal Structure of Regulator of Polyketide Synthase Expression BAD_0249 from Bifidobacterium adolescentis To be Published 0 0 0 0
3JRR Crystal structure of the ligand binding suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor 2009-09-08 2010-09-15 Chan, J.,Yamazaki, H.,Ishiyama, N.,Mal, T.K.,Michikawa, T.,Mikoshiba, K.,Ikura, M. A 1.9 angstrom crystal structure of the suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor To be Published 0 0 0 0
3NNV 20800479 Crystal structure of P38 alpha in complex with DP437 2010-06-24 2010-09-15 Ahn, Y.M.,Clare, M.,Ensinger, C.L.,Hood, M.M.,Lord, J.W.,Lu, W.P.,Miller, D.F.,Patt, W.C.,Smith, B.D.,Vogeti, L.,Kaufman, M.D.,Petillo, P.A.,Wise, S.C.,Abendroth, J.,Chun, L.,Clark, R.,Feese, M.,Kim, H.,Stewart, L.,Flynn, D.L. Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett. 2010 20 5793 5798
3NRV Crystal structure of MarR/EmrR family transcriptional regulator from Acinetobacter sp. ADP1 2010-06-30 2010-09-15 Rongguang, Z.,Ruiying, W.,Andrzej, J.,Midwest Center for Structural Genomics (MCSG) Crystal structure of MarR/EmrR family transcriptional regulator from Acinetobacter sp. ADP1 To be Published 0 0 0 0
3OLO Crystal structure of a PAS domain from two-component sensor histidine kinase 2010-08-26 2010-09-15 Michalska, K.,Chhor, G.,Bearden, J.,Fenske, R.J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of a PAS domain from two-component sensor histidine kinase To be Published 0 0 0 0
3OP9 Crystal structure of transcriptional regulator from Listeria innocua 2010-08-31 2010-09-15 Michalska, K.,Li, H.,Gu, M.,Joachimiak, A. Crystal structure of transcriptional regulator from Listeria innocua To be Published 0 0 0 0
3OPC Crystal structure of FlgN chaperone from Bordetella pertussis 2010-08-31 2010-09-15 Michalska, K.,Chhor, G.,Bearden, J.,Fenske, R.J.,Joachimiak, A. Crystal structure of FlgN chaperone from Bordetella pertussis To be Published 0 0 0 0
3ON1 The structure of a protein with unknown function from Bacillus halodurans C 2010-08-27 2010-09-22 Fan, Y.,Kagan, O.,Savchenko, A.,Joachimiak, A.,Edwards, A. The structure of a protein with unknown function from Bacillus halodurans C To be Published 0 0 0 0
3ON4 Crystal structure of TetR transcriptional regulator from Legionella pneumophila 2010-08-27 2010-09-22 Michalska, K.,Li, H.,Gu, M.,Joachimiak, A. Crystal structure of TetR transcriptional regulator from Legionella pneumophila To be Published 0 0 0 0
3OS4 The Crystal Structure of Nicotinate Phosphoribosyltransferase from Yersinia pestis 2010-09-08 2010-09-22 Maltseva, N.,Kim, Y.,Gu, M.,Anderson, W.F.,Joachimiak, A. The Crystal Structure of Nicotinate Phosphoribosyltransferase from Yersinia pestis TO BE PUBLISHED 0 0 0 0
3N5A 20824061 Synaptotagmin-7, C2B-domain, calcium bound 2010-05-24 2010-09-29 Xue, M.,Craig, T.K.,Shin, O.H.,Li, L.,Brautigam, C.A.,Tomchick, D.R.,Sudhof, T.C.,Rosenmund, C.,Rizo, J. Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One 2010 5 12544 12544
3OP1 Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae 2010-08-31 2010-09-29 Kim, Y.,Li, H.,Cobb, G.,Joachimiak, A. Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae TO BE PUBLISHED 0 0 0 0
3OCJ The crystal structure of a possilbe exported protein from Bordetella parapertussis 2010-08-10 2010-10-06 Tan, K.,Bigelow, L.,Buck, K.,Joachimiak, A. The crystal structure of a possilbe exported protein from Bordetella parapertussis To be Published 0 0 0 0
3P2A Crystal Structure of Thioredoxin 2 from Yersinia pestis 2010-10-01 2010-10-13 Kim, Y.,Zhou, M.,Grimshaw, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Thioredoxin 2 from Yersinia pestis TO BE PUBLISHED 0 0 0 0
3OZH Crystal Structure of Beta-Lactamase/D-alanine Carboxypeptidase from Yersinia pestis 2010-09-24 2010-10-20 Kim, Y.,Zhou, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Beta-Lactamase/D-alanine Carboxypeptidase from Yersinia pestis To be Published 0 0 0 0
3OVK Crystal structure of an XXA-pro aminopeptidase from Streptococcus pyogenes 2010-09-16 2010-11-03 Joachimiak, A.,Duke, N.E.C.,Volkart, L.,Clancy, S.,Midwest Center for Structural Genomics (MCSG) Crystal structure of an XXA-pro aminopeptidase from Streptococcus pyogenes To be Published 0 0 0 0
3OWC Crystal structure of GNAT superfamily protein PA2578 from Pseudomonas aeruginosa 2010-09-17 2010-11-03 Majorek, K.A.,Chruszcz, M.,Joachimiak, A.,Minor, W. Crystal structure of GNAT superfamily protein PA2578 from Pseudomonas aeruginosa To be Published 0 0 0 0
3PEB The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus. 2010-10-25 2010-11-03 Cuff, M.E.,Mack, J.C.,Clancy, S.,Joachimiak, A. The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus. TO BE PUBLISHED 0 0 0 0
3OOS The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne 2010-08-31 2010-11-10 Fan, Y.,Tan, K.,Bigelow, L.,Hamilton, J.,Li, H.,Zhou, Y.,Clancy, S.,Buck, K.,Joachimiak, A. The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne To be Published 0 0 0 0
3PF6 The structure of uncharacterized protein PP-LUZ7_gp033 from Pseudomonas phage LUZ7. 2010-10-28 2010-11-10 Cuff, M.E.,Evdokimova, E.,Liu, F.,Edwards, A.,Savchenko, A.,Joachimiak, A. The structure of uncharacterized protein PP-LUZ7_gp033 from Pseudomonas phage LUZ7. TO BE PUBLISHED 0 0 0 0
3O1O 21068844 Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase 2010-07-21 2010-11-17 Yi, C.,Jia, G.,Hou, G.,Dai, Q.,Zhang, W.,Zheng, G.,Jian, X.,Yang, C.-G.,Cui, Q.,He, C. Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase Nature 2010 468 330 333
3KM1 ZINC-Reconstituted TOMATO CHLOROPLAST SUPEROXIDE DISMUTASE 2009-11-09 2010-12-01 Galaleldeen, A.,Taylor, A.B.,Thomas, S.T.,Jart, P.J. Biophysical properties of tomato chloroplast sod To be Published 0 0 0 0
3PGP 24003232 Crystal structure of PA4794 - GNAT superfamily protein in complex with AcCoA 2010-11-02 2010-12-01 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J.Biol.Chem. 2013 288 30223 30235
3O3A 20806940 Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1 2010-07-23 2010-12-08 Douat-Casassus, C.,Borbulevych, O.,Tarbe, M.,Gervois, N.,Jotereau, F.,Baker, B.M.,Quideau, S. Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition. J.Med.Chem. 2010 53 7061 7066
3O3D 20806940 Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2 2010-07-23 2010-12-08 Douat-Casassus, C.,Borbulevych, O.,Tarbe, M.,Gervois, N.,Jotereau, F.,Baker, B.M.,Quideau, S. Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition. J.Med.Chem. 2010 53 7061 7066
3PD7 Crystal Structure of the Sixth BRCT Domain of Human TopBP1 2010-10-22 2010-12-08 Lee, J.,Xu, C.,Cui, G.,Thompson, J.R.,Mer, G. Crystal Structure of the Sixth BRCT Domain of Human TopBP1 To be Published 0 0 0 0
3O26 21169353 The structure of salutaridine reductase from Papaver somniferum. 2010-07-22 2010-12-15 Higashi, Y.,Kutchan, T.M.,Smith, T.J. The atomic structure of salutaridine reductase from the opium poppy Papaver somniferum. J.Biol.Chem. 2010 66 163 166
3OXZ 21118377 Crystal structure of ABL kinase domain bound with a DFG-out inhibitor AP24534 2010-09-22 2010-12-15 Zhou, T.,Commodore, L.,Huang, W.S.,Wang, Y.,Thomas, M.,Keats, J.,Xu, Q.,Rivera, V.M.,Shakespeare, W.C.,Clackson, T.,Dalgarno, D.C.,Zhu, X. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem.Biol.Drug Des. 2011 77 1 11
3OY3 21118377 Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589 2010-09-22 2010-12-15 Zhou, T.,Commodore, L.,Huang, W.S.,Wang, Y.,Thomas, M.,Keats, J.,Xu, Q.,Rivera, V.M.,Shakespeare, W.C.,Clackson, T.,Dalgarno, D.C.,Zhu, X. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem.Biol.Drug Des. 2011 77 1 11
3NHI 21152418 Crystal structure of the AnSt-D7L1-leukotriene C4 complex 2010-06-14 2010-12-29 Alvarenga, P.H.,Francischetti, I.M.,Calvo, E.,Sa-Nunes, A.,Ribeiro, J.M.,Andersen, J.F. The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite. Plos Biol. 2010 8 0 0
3NHT 21152418 Crystal structure of the AnSt-D7L1-U46619 complex 2010-06-14 2010-12-29 Alvarenga, P.H.,Francischetti, I.M.,Calvo, E.,Sa-Nunes, A.,Ribeiro, J.M.,Andersen, J.F. The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite. Plos Biol. 2010 8 0 0
3OUE 21130881 Structure of C-terminal hexaheme fragment of GSU1996 2010-09-14 2010-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Duke, N.E.,Pessanha, M.,Yang, X.,Orshonsky, V.,Orshonsky, L.,Erickson, J.,Zagyanskiy, Y.,Salgueiro, C.A.,Schiffer, M. Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes. J.Struct.Biol. 2011 174 223 233
3OUQ 21130881 Structure of N-terminal hexaheme fragment of GSU1996 2010-09-15 2010-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Duke, N.E.,Pessanha, M.,Yang, X.,Orshonsky, V.,Orshonsky, L.,Erickson, J.,Zagyanskiy, Y.,Salgueiro, C.A.,Schiffer, M. Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes. J.Struct.Biol. 2011 174 223 233
3OV0 21130881 Structure of dodecaheme cytochrome c GSU1996 2010-09-15 2010-12-29 Pokkuluri, P.R.,Londer, Y.Y.,Duke, N.E.,Pessanha, M.,Yang, X.,Orshonsky, V.,Orshonsky, L.,Erickson, J.,Zagyanskiy, Y.,Salgueiro, C.A.,Schiffer, M. Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes. J.Struct.Biol. 2011 174 223 233
3Q0I Methionyl-tRNA formyltransferase from Vibrio cholerae 2010-12-15 2010-12-29 Osipiuk, J.,Gu, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Methionyl-tRNA formyltransferase from Vibrio cholerae. To be Published 0 0 0 0
3ODX Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF 2010-08-12 2011-01-05 Chen, Z.,Guo, L.,Sprang, S.R.,Sternweis, P.C. Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF Protein Sci. 2011 20 107 117
3Q62 Crystal Structure of 3-hydroxydecanoyl-(acyl carrier protein) dehydratase from Yersinia pestis 2010-12-30 2011-01-12 Zhang, R.,Maltseva, N.,Kwon, K.,Anderson, W.F.,Joachimiak, A.,CSGID Crystal Structure of 3-hydroxydecanoyl-(acyl carrier protein) dehydratase from Yersinia pestis To be Published 0 0 0 0
3Q2I 21241053 Crystal structure of the WlbA dehydrognase from Chromobactrium violaceum in complex with NADH and UDP-GlcNAcA at 1.50 A resolution 2010-12-20 2011-01-19 Thoden, J.B.,Holden, H.M. Biochemical and Structural Characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: Enzymes Required for the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid. Biochemistry 2011 50 1483 1491
3Q2K 21241053 Crystal structure of the WlbA dehydrogenase from Bordetella pertussis in complex with NADH and UDP-GlcNAcA 2010-12-20 2011-01-19 Thoden, J.B.,Holden, H.M. Biochemical and Structural Characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: Enzymes Required for the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid. Biochemistry 2011 50 1483 1491
3P7J 21472955 Drosophila HP1a chromo shadow domain 2010-10-12 2011-02-02 Mendez, D.L.,Kim, D.,Chruszcz, M.,Stephens, G.E.,Minor, W.,Khorasanizadeh, S.,Elgin, S.C. The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners. Chembiochem 2011 12 1084 1096
3QDN Putative thioredoxin protein from Salmonella typhimurium 2011-01-18 2011-02-09 Osipiuk, J.,Zhou, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Putative thioredoxin protein from Salmonella typhimurium. To be Published 0 0 0 0
3QJG Epidermin biosynthesis protein EpiD from Staphylococcus aureus 2011-01-28 2011-02-09 Osipiuk, J.,Makowska-Grzyska, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Epidermin biosynthesis protein EpiD from Staphylococcus aureus. To be Published 0 0 0 0
3N75 21278708 X-ray Crystal Structure of the Escherichia coli Inducible Lysine Decarboxylase LdcI 2010-05-26 2011-02-16 Kanjee, U.,Gutsche, I.,Alexopoulos, E.,Zhao, B.,El Bakkouri, M.,Thibault, G.,Liu, K.,Ramachandran, S.,Snider, J.,Pai, E.F.,Houry, W.A. Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase. Embo J. 2011 30 931 944
3LKT Tyrosine 447 of Protocatechuate 3,4-Dioxygenase Controls Efficient Progress Through Catalysis 2010-01-27 2011-02-23 Purpero, V.M.,Valley, M.P.,Ohlendorf, D.H.,Lipscomb, J.D.,Burk, D.,Dolbeare, K.B.,Brown, K.C. Tyrosine 447 of Protocatechuate 3,4-Dioxygenase Controls Efficient Progress Through Catalysis To be Published 0 0 0 0
3QN3 Phosphopyruvate hydratase from Campylobacter jejuni. 2011-02-07 2011-02-23 Osipiuk, J.,Gu, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Phosphopyruvate hydratase from Campylobacter jejuni. To be Published 0 0 0 0
3PTG 21316234 Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor 2010-12-02 2011-03-02 Bowers, S.,Truong, A.P.,Neitz, R.J.,Neitzel, M.,Probst, G.D.,Hom, R.K.,Peterson, B.,Galemmo, R.A.,Konradi, A.W.,Sham, H.L.,Toth, G.,Pan, H.,Yao, N.,Artis, D.R.,Brigham, E.F.,Quinn, K.P.,Sauer, J.M.,Powell, K.,Ruslim, L.,Ren, Z.,Bard, F.,Yednock, T.A.,Griswold-Prenner, I. Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorg.Med.Chem.Lett. 2011 21 1838 1843
3PWJ 21282516 Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant 2010-12-08 2011-03-09 Borbulevych, O.Y.,Piepenbrink, K.H.,Baker, B.M. Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics. J.Immunol. 2011 186 2950 2958
3PWL 21282516 Human Class I MHC HLA-A2 in complex with the HuD peptide 2010-12-08 2011-03-09 Borbulevych, O.Y.,Piepenbrink, K.H.,Baker, B.M. Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics. J.Immunol. 2011 186 2950 2958
3PWN 21282516 Human Class I MHC HLA-A2 in complex with the HuD (G2L) peptide variant 2010-12-08 2011-03-09 Borbulevych, O.Y.,Piepenbrink, K.H.,Baker, B.M. Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics. J.Immunol. 2011 186 2950 2958
3QTY Crystal structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis complexed with pyrophosphate 2011-02-23 2011-03-16 Maltseva, N.,Kim, Y.,Hasseman, J.,Anderson, W.F.,Joachimiak, A. Crystal structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis complexed with pyrophosphate To be Published 0 0 0 0
3OA7 21454609 Structure of the C-terminal domain of Cnm67, a core component of the spindle pole body of Saccharomyces cerevisiae 2010-08-04 2011-03-23 Klenchin, V.A.,Frye, J.J.,Jones, M.H.,Winey, M.,Rayment, I. Structure-function analysis of the C-terminal domain of CNM67, a core component of the Saccharomyces cerevisiae spindle pole body. J.Biol.Chem. 2011 286 18240 18250
3R0A Possible transcriptional regulator from Methanosarcina mazei Go1 (gi 21227196) 2011-03-07 2011-03-23 Joachimiak, A.,Duke, N.E.C.,Li, H.,Gu, M. Possible transcriptional regulator from Methanosarcina mazei Go1 (gi 21227196) To be Published 0 0 0 0
3R2E Dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase from Yersinia pestis. 2011-03-14 2011-03-23 Osipiuk, J.,Maltseva, N.,Makowska-Grzyska, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase from Yersinia pestis To be Published 0 0 0 0
3QXC 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ATP 2011-03-01 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3QXH 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ADP and 8-aminocaprylic acid 2011-03-01 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3QXJ 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GTP 2011-03-01 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3QXS 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ANP 2011-03-02 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3QXX 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid 2011-03-02 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3QY0 22284390 Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP 2011-03-02 2011-03-30 Porebski, P.J.,Klimecka, M.,Chruszcz, M.,Nicholls, R.A.,Murzyn, K.,Cuff, M.E.,Xu, X.,Cymborowski, M.,Murshudov, G.N.,Savchenko, A.,Edwards, A.,Minor, W. Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J. 2012 279 1093 1105
3MFL Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2010-04-02 2011-04-13 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
3QVM 23877221 The structure of olei00960, a hydrolase from Oleispira antarctica 2011-02-25 2011-04-13 Kube, M.,Chernikova, T.N.,Al-Ramahi, Y.,Beloqui, A.,Lopez-Cortez, N.,Guazzaroni, M.E.,Heipieper, H.J.,Klages, S.,Kotsyurbenko, O.R.,Langer, I.,Nechitaylo, T.Y.,Lunsdorf, H.,Fernandez, M.,Juarez, S.,Ciordia, S.,Singer, A.,Kagan, O.,Egorova, O.,Alain Petit, P.,Stogios, P.,Kim, Y.,Tchigvintsev, A.,Flick, R.,Denaro, R.,Genovese, M.,Albar, J.P.,Reva, O.N.,Martinez-Gomariz, M.,Tran, H.,Ferrer, M.,Savchenko, A.,Yakunin, A.F.,Yakimov, M.M.,Golyshina, O.V.,Reinhardt, R.,Golyshin, P.N. Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun 2013 4 2156 2156
3QVQ The structure of an Oleispira antarctica phosphodiesterase OLEI02445 in complex with the product sn-glycerol-3-phosphate 2011-02-25 2011-04-13 Singer, A.U.,Kagan, O.,Evdokimova, E.,Cuff, M.E.,Edwards, A.M.,Joachimiak, A.,Yakunin, A.F.,Savchenko, A. The structure of an Oleispira antarctica phosphodiesterase OLEI02445 in complex with the product sn-glycerol-3-phosphate To be Published 0 0 0 0
3R1X 21795809 Crystal structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae 2011-03-11 2011-04-13 Michalska, K.,Cuff, M.E.,Tesar, C.,Feldmann, B.,Joachimiak, A. Structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae. Acta Crystallogr.,Sect.D 2011 67 678 689
3PKB 21465667 M. tuberculosis MetAP with bengamide analog Y16, in Mn form 2010-11-11 2011-04-20 Lu, J.P.,Yuan, X.H.,Yuan, H.,Wang, W.L.,Wan, B.,Franzblau, S.G.,Ye, Q.Z. Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem 2011 6 1041 1048
3PKC 21465667 M. tuberculosis MetAP with bengamide analog Y08, in Mn form 2010-11-11 2011-04-20 Lu, J.P.,Yuan, X.H.,Yuan, H.,Wang, W.L.,Wan, B.,Franzblau, S.G.,Ye, Q.Z. Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem 2011 6 1041 1048
3PKD 21465667 M. tuberculosis MetAP with bengamide analog Y10, in Mn form 2010-11-11 2011-04-20 Lu, J.P.,Yuan, X.H.,Yuan, H.,Wang, W.L.,Wan, B.,Franzblau, S.G.,Ye, Q.Z. Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem 2011 6 1041 1048
3PKE 21465667 M. tuberculosis MetAP with bengamide analog Y10, in Ni form 2010-11-11 2011-04-20 Lu, J.P.,Yuan, X.H.,Yuan, H.,Wang, W.L.,Wan, B.,Franzblau, S.G.,Ye, Q.Z. Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem 2011 6 1041 1048
3R7T Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni 2011-03-23 2011-04-20 Kim, Y.,Gu, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni To be Published 0 0 0 0
3MI5 Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2010-04-09 2011-04-27 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
3RHT Crystal structure of type 1 glutamine amidotransferase (GATase1)-like protein from Planctomyces limnophilus 2011-04-12 2011-04-27 Michalska, K.,Li, H.,Bearden, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of type 1 glutamine amidotransferase (GATase1)-like protein from Planctomyces limnophilus To be Published 0 0 0 0
3RJU Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate 2011-04-15 2011-04-27 Kim, Y.,Zhou, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate To be Published 0 0 0 0
3MOW Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1 2010-04-23 2011-05-04 Zhang, Z.-Y.,Liu, S.,Yu, Z.,Yu, X.,Huang, S.-X.,Luo, Y.,Wu, L.,Yang, Z.,Wang, L.,Gunawan, A.M.,Chan, R.J.,Shen, B. Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1 To be Published 0 0 0 0
3OXI 21071223 Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of JNK for the Treatment of Neurodegenerative Diseases 2010-09-21 2011-05-04 Hom, R.K.,Bowers, S.,Sealy, J.M.,Truong, A.P.,Probst, G.D.,Neitzel, M.L.,Neitz, R.J.,Fang, L.,Brogley, L.,Wu, J.,Konradi, A.W.,Sham, H.L.,Toth, G.,Pan, H.,Yao, N.,Artis, D.R.,Quinn, K.,Sauer, J.M.,Powell, K.,Ren, Z.,Bard, F.,Yednock, T.A.,Griswold-Prenner, I. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg.Med.Chem.Lett. 2010 20 7303 7307
3RMQ Crystal structure of uncharacterized protein Svir_20580 from Saccharomonospora viridis (V71M mutant) 2011-04-21 2011-05-11 Michalska, K.,Weger, A.,Hatzos-Skintges, C.,Bearden, J.,Joachimiak, A. Crystal structure of uncharacterized protein Svir_20580 from Saccharomonospora viridis (V71M mutant) To be Published 0 0 0 0
3RMS Crystal structure of uncharacterized protein Svir_20580 from Saccharomonospora viridis 2011-04-21 2011-05-11 Michalska, K.,Weger, A.,Hatzos-Skintges, C.,Bearden, J.,Joachimiak, A. Crystal structure of uncharacterized protein Svir_20580 from Saccharomonospora viridis To be Published 0 0 0 0
3RPW 23606130 The crystal structure of an ABC transporter from Rhodopseudomonas palustris CGA009 2011-04-27 2011-05-11 Tan, K.,Chang, C.,Cuff, M.,Osipiuk, J.,Landorf, E.,Mack, J.C.,Zerbs, S.,Joachimiak, A.,Collart, F.R. Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins 2013 81 1709 1726
3RSB 21542645 Structure of the Archaeal GTP:AdoCbi-P Guanylyltransferase (CobY) from Methanocaldococcus jannaschii 2011-05-02 2011-05-18 Newmister, S.A.,Otte, M.M.,Escalante-Semerena, J.C.,Rayment, I. Structure and Mutational Analysis of the Archaeal GTP:AdoCbi-P Guanylyltransferase (CobY) from Methanocaldococcus jannaschii: Insights into GTP Binding and Dimerization. Biochemistry 2011 50 5301 5313
3MV4 Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2010-05-03 2011-06-01 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
3MV6 Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2010-05-03 2011-06-01 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
3PIC 21661060 Glucuronoyl Esterase catalytic domain (Cip2_GE) from Hypocrea jecorina 2010-11-05 2011-06-01 Pokkuluri, P.R.,Duke, N.E.,Wood, S.J.,Cotta, M.A.,Li, X.L.,Biely, P.,Schiffer, M. Structure of the catalytic domain of glucuronoyl esterase Cip2 from Hypocrea jecorina. Proteins 2011 79 2588 2592
3S3T Universal stress protein UspA from Lactobacillus plantarum 2011-05-18 2011-06-08 Osipiuk, J.,Li, H.,Cobb, G.,Joachimiak, A. Universal stress protein UspA from Lactobacillus plantarum. To be Published 0 0 0 0
3P8D 22864287 Crystal structure of the second Tudor domain of human PHF20 (homodimer form) 2010-10-13 2011-06-22 Cui, G.,Park, S.,Badeaux, A.I.,Kim, D.,Lee, J.,Thompson, J.R.,Yan, F.,Kaneko, S.,Yuan, Z.,Botuyan, M.V.,Bedford, M.T.,Cheng, J.Q.,Mer, G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat.Struct.Mol.Biol. 2012 19 916 924
3RT7 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with ADP-glucose 2011-05-03 2011-06-22 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RT9 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with Coenzyme A 2011-05-03 2011-06-22 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RTC 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NAD and ATP. 2011-05-03 2011-06-22 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RTE 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADP and ATP. 2011-05-03 2011-06-22 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RXY Crystal structure of NIF3 superfamily protein from Sphaerobacter thermophilus 2011-05-10 2011-06-22 Michalska, K.,Tesar, C.,Clancy, S.,Otwinowski, Z.,Joachimiak, A. Crystal structure of NIF3 superfamily protein from Sphaerobacter thermophilus To be Published 0 0 0 0
3RXZ Crystal structure of putative polysaccharide deacetylase from Mycobacterium smegmatis 2011-05-10 2011-06-22 Michalska, K.,Tesar, C.,Bearden, J.,Joachimiak, A. Crystal structure of putative polysaccharide deacetylase from Mycobacterium smegmatis To be Published 0 0 0 0
3S2W The crystal structure of a MarR transcriptional regulator from Methanosarcina mazei Go1 2011-05-17 2011-06-22 Tan, K.,Li, H.,Gu, M.,Joachimiak, A. The crystal structure of a MarR transcriptional regulator from Methanosarcina mazei Go1 To be Published 0 0 0 0
3OLR PTPN22 in complex with consensus phospho-tyrosine peptide 1 2010-08-26 2011-06-29 Yu, X.,Sun, J.P.,Chen, M.,Zhang, S.,Wang, L.,Imasaki, T.,Takagi, Y.,Zhang, Z.Y. Structure basis of LYP substrate specificity revealed by reverse alanine screening and crystallography To be Published 0 0 0 0
3OMH 21719704 Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide 2010-08-26 2011-06-29 Yu, X.,Chen, M.,Zhang, S.,Yu, Z.H.,Sun, J.P.,Wang, L.,Liu, S.,Imasaki, T.,Takagi, Y.,Zhang, Z.Y. Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate. J.Biol.Chem. 2011 286 30526 30534
3Q7V 21775440 Beta-Lactam-Sensor Domain of BlaR1 (Apo) from Staphylococcus Aureus with Carboxylated Lys392 2011-01-05 2011-06-29 Borbulevych, O.,Kumarasiri, M.,Wilson, B.,Llarrull, L.I.,Lee, M.,Hesek, D.,Shi, Q.,Peng, J.,Baker, B.M.,Mobashery, S. Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J.Biol.Chem. 2011 286 31466 31472
3RNR Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans 2011-04-22 2011-06-29 Kim, Y.,Li, H.,Clancy, S.,Joachimiak, A. Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans To be Published 0 0 0 0
3Q7Z 21775440 CBAP-acylated BlaR1 sensor domain from Staphylococcus aureus 2011-01-05 2011-07-06 Borbulevych, O.,Kumarasiri, M.,Wilson, B.,Llarrull, L.I.,Lee, M.,Hesek, D.,Shi, Q.,Peng, J.,Baker, B.M.,Mobashery, S. Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J.Biol.Chem. 2011 286 31466 31472
3QDM 21795600 The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide 2011-01-18 2011-07-06 Borbulevych, O.Y.,Santhanagopolan, S.M.,Hossain, M.,Baker, B.M. TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms. J.Immunol. 2011 187 2453 2463
3QEU 21795600 The crystal structure of TCR DMF5 2011-01-20 2011-07-06 Borbulevych, O.Y.,Santhanagopolan, S.M.,Hossain, M.,Baker, B.M. TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms. J.Immunol. 2011 187 2453 2463
3RE2 21757704 Crystal structure of menin reveals the binding site for Mixed Lineage Leukemia (MLL) protein 2011-04-02 2011-07-13 Murai, M.J.,Chruszcz, M.,Reddy, G.,Grembecka, J.,Cierpicki, T. Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein. J.Biol.Chem. 2011 286 31742 31748
3SQN Putative Mga family transcriptional regulator from Enterococcus faecalis 2011-07-05 2011-07-20 Osipiuk, J.,Wu, R.,Jedrzejczak, R.,Moy, S.,Joachimiak, A. Putative Mga family transcriptional regulator from Enterococcus faecalis. To be Published 0 0 0 0
3RPH 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+. 2011-04-26 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RPZ 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+ and soaked with NADPH 2011-04-27 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQ2 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+ and soaked with NADH 2011-04-27 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQ5 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+ and soaked with CoA 2011-04-27 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQ6 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis soaked with ADP-ribose 2011-04-27 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQ8 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis soaked with P1,P5-Di(adenosine-5') pentaphosphate 2011-04-27 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQH 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P6-Di(adenosine-5') hexaphosphate 2011-04-28 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQQ 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P3-Di(adenosine-5') triphosphate 2011-04-28 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RQX 22940582 Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P4-Di(adenosine-5') tetraphosphate 2011-04-28 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RRE 22940582 Crystal Structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with ADP 2011-04-29 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RRF 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with ATP 2011-04-29 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3RSG 22940582 Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NAD. 2011-05-02 2011-07-27 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3QSD 21832058 Structure of cathepsin B1 from Schistosoma mansoni in complex with CA074 inhibitor 2011-02-21 2011-08-10 Jilkova, A.,Rezacova, P.,Lepsik, M.,Horn, M.,Vachova, J.,Fanfrlik, J.,Brynda, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem. 2011 286 35770 35781
3S3Q 21832058 Structure of cathepsin B1 from Schistosoma mansoni in complex with K11017 inhibitor 2011-05-18 2011-08-10 Jilkova, A.,Rezacova, P.,Lepsik, M.,Horn, M.,Vachova, J.,Fanfrlik, J.,Brynda, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem. 2011 286 35770 35781
3S3R 21832058 Structure of cathepsin B1 from Schistosoma mansoni in complex with K11777 inhibitor 2011-05-18 2011-08-10 Jilkova, A.,Rezacova, P.,Lepsik, M.,Horn, M.,Vachova, J.,Fanfrlik, J.,Brynda, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem. 2011 286 35770 35781
3SHO Crystal structure of RpiR transcription factor from Sphaerobacter thermophilus (sugar isomerase domain) 2011-06-16 2011-08-10 Michalska, K.,Tesar, C.,Clancy, S.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of RpiR transcription factor from Sphaerobacter thermophilus (sugar isomerase domain) TO BE PUBLISHED 0 0 0 0
3SZ3 Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan 2011-07-18 2011-09-14 Cooper, D.R.,Kudritska, M.,Chruszcz, M.,Grabowski, M.,Anderson, W.F.,Minor, W. Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan To be Published 0 0 0 0
3T7B Crystal Structure of N-acetyl-L-glutamate kinase from Yersinia pestis 2011-07-29 2011-09-14 Demas, M.W.,Solberg, R.G.,Cooper, D.R.,Chruszcz, M.,Porebski, P.J.,Zheng, H.,Onopriyenko, O.,Skarina, T.,Savchenko, A.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of N-acetyl-L-glutamate kinase from Yersinia pestis To be Published 0 0 0 0
3TNJ 23745136 Crystal structure of universal stress protein from Nitrosomonas europaea with AMP bound 2011-09-01 2011-09-14 Tkaczuk, K.L.,Shumilin, I.A.,Chruszcz, M.,Evdokimova, E.,Savchenko, A.,Minor, W. Structural and functional insight into the universal stress protein family. Evol Appl 2013 6 434 449
3QFD 21937447 Human Class I MHC HLA-A2 in complex with Mart-1(27-35) nonameric peptide 2011-01-21 2011-09-28 Insaidoo, F.K.,Borbulevych, O.Y.,Hossain, M.,Santhanagopolan, S.M.,Baxter, T.K.,Baker, B.M. Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN. J.Biol.Chem. 2011 286 40163 40173
3TL0 21800896 Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide 2011-08-29 2011-09-28 Zhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.,Pei, D. Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry 2011 50 7637 7646
3T4D 21933962 Crystal Structure of NaK2K Channel Y55F Mutant 2011-07-25 2011-10-05 Sauer, D.B.,Zeng, W.,Raghunathan, S.,Jiang, Y. Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA 2011 108 16634 16639
3T4Z 21933962 Crystal Structure of NaK2K Channel Y55W Mutant 2011-07-26 2011-10-05 Sauer, D.B.,Zeng, W.,Raghunathan, S.,Jiang, Y. Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA 2011 108 16634 16639
3TY6 ATP-dependent Protease HslV from Bacillus anthracis str. Ames 2011-09-23 2011-10-05 Kim, Y.,Mulligan, R.,Kwon, K.,Anderson, W.F.,Joachimiak, A. ATP-dependent Protease HslV from Bacillus anthracis str. Ames To be Published 0 0 0 0
3TZL Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni complexed with ADP and Tryptophane 2011-09-27 2011-10-05 Kim, Y.,Zhou, M.,Grimshaw, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni complexed with ADP and Tryptophane To be Published 0 0 0 0
3TYK 21084294 Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia 2011-09-26 2011-10-12 Stogios, P.J.,Shakya, T.,Evdokimova, E.,Savchenko, A.,Wright, G.D. Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme. J.Biol.Chem. 2011 286 1966 1975
3TY7 Crystal Structure of Aldehyde Dehydrogenase family Protein from Staphylococcus aureus 2011-09-23 2011-10-19 Kim, Y.,Joachimiak, G.,Jedrzejczak, R.,Rubin, E.,Ioerger, T.,Sacchettini, J.,Joachimiak, A. Crystal Structure of Aldehyde Dehydrogenase family Protein from Staphylococcus aureus To be Published 0 0 0 0
3TZC 26553852 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(Y155F) from Vibrio cholerae 2011-09-27 2011-10-19 Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W. Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol. 2015 198 463 476
3TZK 26553852 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92A) from Vibrio cholerae 2011-09-27 2011-10-19 Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W. Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol. 2015 198 463 476
3U09 26553852 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae 2011-09-28 2011-10-19 Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W. Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol. 2015 198 463 476
3RZ2 22009749 Crystal of Prl-1 complexed with peptide 2011-05-11 2011-10-26 Bai, Y.,Luo, Y.,Liu, S.,Zhang, L.,Shen, K.,Dong, Y.,Walls, C.D.,Quilliam, L.A.,Wells, C.D.,Cao, Y.,Zhang, Z.Y. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. J.Biol.Chem. 2011 286 42316 42324
3TKZ 21800896 Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide 2011-08-29 2011-10-26 Zhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.,Pei, D. Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry 2011 50 7637 7646
3UO2 22306468 Jac1 co-chaperone from Saccharomyces cerevisiae 2011-11-16 2011-12-14 Ciesielski, S.J.,Schilke, B.A.,Osipiuk, J.,Bigelow, L.,Mulligan, R.,Majewska, J.,Joachimiak, A.,Marszalek, J.,Craig, E.A.,Dutkiewicz, R. Interaction of j-protein co-chaperone jac1 with fe-s scaffold isu is indispensable in vivo and conserved in evolution. J.Mol.Biol. 2012 417 1 12
3PS8 Crystal structure of L68V mutant of human cystatin C 2010-12-01 2011-12-21 Orlikowska, M.,Szymanska, A.,Borek, D.,Otwinowski, Z.,Skowron, P.,Jankowska, E. Crystal structure of L68V mutant of human cystatin C To be Published 0 0 0 0
3U4G The Structure of CobT from Pyrococcus horikoshii 2011-10-07 2011-12-21 Cuff, M.E.,Evdokimova, E.,Mursleen, A.,Savchenko, A.,Edwards, A.,Joachimiak, A. The Structure of CobT from Pyrococcus horikoshii TO BE PUBLISHED 0 0 0 0
3UXV Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ 2011-12-05 2011-12-28 Kim, Y.,Zhou, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,CSGID Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ To be Published 2012 0 0 0
3V4Z D-alanine--D-alanine ligase from Yersinia pestis 2011-12-15 2011-12-28 Osipiuk, J.,Nocek, B.,Mulligan, R.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. D-alanine--D-alanine ligase from Yersinia pestis. To be Published 0 0 0 0
3QH3 22019736 The crystal structure of TCR A6 2011-01-25 2012-01-04 Scott, D.R.,Borbulevych, O.Y.,Piepenbrink, K.H.,Corcelli, S.A.,Baker, B.M. Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism. J.Mol.Biol. 2011 414 385 400
3UXJ Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ0 2011-12-05 2012-01-04 Kim, Y.,Zhang, R.,Gu, M.,Anderson, W.F.,Joachimiak, A.,CSGID Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ0 To be Published 2012 0 0 0
3V08 22677715 Crystal structure of Equine Serum Albumin 2011-12-07 2012-01-11 Majorek, K.A.,Porebski, P.J.,Dayal, A.,Zimmerman, M.D.,Jablonska, K.,Stewart, A.J.,Chruszcz, M.,Minor, W. Structural and immunologic characterization of bovine, horse, and rabbit serum albumins. Mol.Immunol. 2012 52 174 182
3VCX Crystal structure of a putative glyoxalase/bleomycin resistance protein from Rhodopseudomonas palustris CGA009 2012-01-04 2012-01-18 Stogios, P.J.,Chang, C.,Evdokimova, E.,Egorova, O.,Joachimiak, A.,Edwards, A.M.,Savchenko, A. Crystal structure of a putative glyoxalase/bleomycin resistance protein from Rhodopseudomonas palustris CGA009 To be Published 0 0 0 0
3V5X 22253436 Structure of FBXL5 hemerythrin domain, C2 cell 2011-12-17 2012-01-25 Thompson, J.W.,Salahudeen, A.A.,Chollangi, S.,Ruiz, J.C.,Brautigam, C.A.,Makris, T.M.,Lipscomb, J.D.,Tomchick, D.R.,Bruick, R.K. Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem. 2012 287 7357 7365
3V5Y 22253436 Structure of FBXL5 hemerythrin domain, P2(1) cell 2011-12-17 2012-01-25 Thompson, J.W.,Salahudeen, A.A.,Chollangi, S.,Ruiz, J.C.,Brautigam, C.A.,Makris, T.M.,Lipscomb, J.D.,Tomchick, D.R.,Bruick, R.K. Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem. 2012 287 7357 7365
4DGT Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate 2012-01-26 2012-02-08 Shabalin, I.G.,Onopriyenko, O.,Kudritska, M.,Grimshaw, S.,Chruszcz, M.,Porebski, P.J.,Cooper, D.R.,Savchenko, A.,Anderson, W.F.,Minor, W. Crystal structures of putative aminotransferase from Clostridium difficile 630 to be published 0 0 0 0
3UJ0 22286060 Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form. 2011-11-07 2012-02-15 Seo, M.D.,Velamakanni, S.,Ishiyama, N.,Stathopulos, P.B.,Rossi, A.M.,Khan, S.A.,Dale, P.,Li, C.,Ames, J.B.,Ikura, M.,Taylor, C.W. Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature 2012 483 108 112
4DM0 11896402 TN5 transposase: 20MER OUTSIDE END 2 MN complex 2012-02-06 2012-02-22 Lovell, S.,Goryshin, I.Y.,Reznikoff, W.R.,Rayment, I. Two-metal active site binding of a TN5 transposase synaptic complex Nat.Struct.Biol. 2002 9 278 281
4DRZ Crystal structure of human RAB14 2012-02-17 2012-02-29 Wang, J.,Tempel, W.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H. Crystal structure of human RAB14 to be published 0 0 0 0
4DQ1 Thymidylate synthase from Staphylococcus aureus. 2012-02-14 2012-03-21 Osipiuk, J.,Holowicki, J.,Jedrzejczak, R.,Rubin, E.,Guinn, K.,Ioerger, T.,Baker, D.,Sacchettini, J.,Joachimiak, A. Thymidylate synthase from Staphylococcus aureus. To be Published 0 0 0 0
3SZ6 22412371 IsdX1, an anthrax hemophore 2011-07-18 2012-03-28 Ekworomadu, M.T.,Poor, C.B.,Owens, C.P.,Balderas, M.A.,Fabian, M.,Olson, J.S.,Murphy, F.,Balkabasi, E.,Honsa, E.S.,He, C.,Goulding, C.W.,Maresso, A.W. Differential function of lip residues in the mechanism and biology of an anthrax hemophore. Plos Pathog. 2012 8 0 0
3U24 The structure of a putative lipoprotein of unknown function from Shewanella oneidensis. 2011-09-30 2012-05-09 Cuff, M.E.,Hatzos-Skintges, C.,Bearden, J.,Joachimiak, A. The structure of a putative lipoprotein of unknown function from Shewanella oneidensis. TO BE PUBLISHED 0 0 0 0
3V75 Crystal structure of putative orotidine 5'-phosphate decarboxylase from Streptomyces avermitilis ma-4680 2011-12-20 2012-05-09 Stogios, P.J.,Xu, X.,Cui, H.,Kudritska, M.,Tan, K.,Edwards, A.,Savchenko, A.,Joachimiak, A. Crystal structure of putative orotidine 5'-phosphate decarboxylase from Streptomyces avermitilis ma-4680 To be Published 0 0 0 0
3S67 23519666 Crystal structure of V57P mutant of human cystatin C 2011-05-25 2012-05-30 Orlikowska, M.,Szymanska, A.,Borek, D.,Otwinowski, Z.,Skowron, P.,Jankowska, E. Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein. Acta Crystallogr.,Sect.D 2013 69 577 586
3V0R 22664167 Crystal structure of Alternaria alternata allergen Alt a 1 2011-12-08 2012-06-13 Chruszcz, M.,Chapman, M.D.,Osinski, T.,Solberg, R.,Demas, M.,Porebski, P.J.,Majorek, K.A.,Pomes, A.,Minor, W. Alternaria alternata allergen Alt a 1: a unique beta-barrel protein dimer found exclusively in fungi. J.Allergy Clin.Immunol. 2012 130 241 0
4FC9 Structure of the C-terminal domain of the type III effector Xcv3220 (XopL) 2012-05-24 2012-06-13 Singer, A.U.,Schulze, S.,Xu, X.,Skarina, T.,Cui, H.,Egler, M.,Srikumar, T.,Raught, B.,Savchenko, A.,Bonas, U. Structure of the C-terminal domain of the type III effector Xcv3220 (XopL) To be Published 0 0 0 0
4FCG Structure of the leucine-rich repeat domain of the type III effector XCV3220 (XopL) 2012-05-24 2012-06-13 Singer, A.U.,Schulze, S.,Xu, X.,Skarina, T.,Cui, H.,Egler, M.,Srikumar, T.,Raught, B.,Savchenko, A.,Bonas, U. Structure of the leucine-rich repeat domain of the type III effector XCV3220 (XopL) To be Published 0 0 0 0
3T3C 22644035 Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV 2011-07-25 2012-06-20 Kozisek, M.,Henke, S.,Saskova, K.G.,Jacobs, G.B.,Schuch, A.,Buchholz, B.,Muller, V.,Krausslich, H.G.,Rezacova, P.,Konvalinka, J.,Bodem, J. Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease. Antimicrob.Agents Chemother. 2012 56 4320 4330
3SEL 23099666 PpcA M58N mutant 2011-06-10 2012-06-27 Pokkuluri, P.R.,Yang, X.,Londer, Y.Y.,Schiffer, M. Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures. J.Struct.Funct.Genom. 2012 13 227 232
3SJ0 23099666 PpcA mutant M58S 2011-06-20 2012-07-04 Pokkuluri, P.R.,Yang, X.,Londer, Y.Y.,Schiffer, M. Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures. J.Struct.Funct.Genom. 2012 13 227 232
3SJ1 23099666 PpcA M58D mutant 2011-06-20 2012-07-04 Pokkuluri, P.R.,Yang, X.,Londer, Y.Y.,Schiffer, M. Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures. J.Struct.Funct.Genom. 2012 13 227 232
3SJ4 23099666 PpcA mutant M58K 2011-06-20 2012-07-04 Pokkuluri, P.R.,Yang, X.,Londer, Y.Y.,Schiffer, M. Pitfalls in the interpretation of structural changes in mutant proteins from crystal structures. J.Struct.Funct.Genom. 2012 13 227 232
3ROG 22940582 Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Thymidine 3'-monophosphate 2011-04-25 2012-07-18 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3ROX 22940582 Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Theophylline 2011-04-26 2012-07-18 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
3ROZ 22940582 Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Nicotinamide 2011-04-26 2012-07-18 Shumilin, I.A.,Cymborowski, M.,Chertihin, O.,Jha, K.N.,Herr, J.C.,Lesley, S.A.,Joachimiak, A.,Minor, W. Identification of unknown protein function using metabolite cocktail screening. Structure 2012 20 1715 1725
4FUT 22773649 Crystal structure of ATP bound MatB from Rhodopseudomonas palustris 2012-06-28 2012-07-25 Crosby, H.A.,Rank, K.C.,Rayment, I.,Escalante-Semerena, J.C. Structure-Guided Expansion of the Substrate Range of Methylmalonyl Coenzyme A Synthetase (MatB) of Rhodopseudomonas palustris. Appl.Environ.Microbiol. 2012 78 6619 6629
3SVA 23519666 Crystal structure of V57D mutant of human cystatin C 2011-07-12 2012-08-01 Orlikowska, M.,Szymanska, A.,Borek, D.,Otwinowski, Z.,Skowron, P.,Jankowska, E. Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein. Acta Crystallogr.,Sect.D 2013 69 577 586
3T63 Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2011-07-28 2012-08-01 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
3T67 Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase 2011-07-28 2012-08-01 Purpero, V.M.,Lipscomb, J.D. Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published 0 0 0 0
4GB7 Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis 2012-07-26 2012-08-08 Osipiuk, J.,Zhou, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis. To be Published 0 0 0 0
4GL0 Putative spermidine/putrescine ABC transporter from Listeria monocytogenes 2012-08-13 2012-08-22 Osipiuk, J.,Zhou, M.,Papazisi, L.,Anderson, W.F.,Joachimiak, A. Putative spermidine/putrescine ABC transporter from Listeria monocytogenes To be Published 0 0 0 0
4GQT N-terminal domain of C. elegans Hsp90 2012-08-23 2012-09-05 Osipiuk, J.,Chhor, G.,Gu, M.,Van Oosten-Hawle, P.,Morimoto, R.I.,Joachimiak, A. N-terminal domain of C. elegans Hsp90 To be Published 0 0 0 0
4FLI 22913487 Human MetAP1 with bengamide analog Y16, in Mn form 2012-06-14 2012-09-19 Xu, W.,Lu, J.P.,Ye, Q.Z. Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem. 2012 55 8021 8027
4FLJ 22913487 Human MetAP1 with bengamide analog Y08, in Mn form 2012-06-14 2012-09-19 Xu, W.,Lu, J.P.,Ye, Q.Z. Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem. 2012 55 8021 8027
4FLK 22913487 Human MetAP1 with bengamide analog Y10, in Mn form 2012-06-14 2012-09-19 Xu, W.,Lu, J.P.,Ye, Q.Z. Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem. 2012 55 8021 8027
4FLL 22913487 Human MetAP1 with bengamide analog YZ6, in Mn form 2012-06-14 2012-09-19 Xu, W.,Lu, J.P.,Ye, Q.Z. Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem. 2012 55 8021 8027
4GB5 Crystal structure of Kfla4162 protein from Kribbella flavida 2012-07-26 2012-09-26 Michalska, K.,Chhor, G.,Endres, M.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of Kfla4162 protein from Kribbella flavida (CASP Target) To be Published 0 0 0 0
4GYM Crystal structure of Glyoxalase/bleomycin resistance protein/dioxygenase from Conexibacter woesei DSM 14684 2012-09-05 2012-09-26 Chang, C.,Tesar, C.,Clancy, S.,Joachimiak, A. Crystal structure of Glyoxalase/bleomycin resistance protein/dioxygenase from Conexibacter woesei DSM 14684 To be Published 0 0 0 0
4GZE 23519420 Crystal structure of 6-phospho-beta-glucosidase from Lactobacillus plantarum (apo form) 2012-09-06 2012-09-26 Michalska, K.,Tan, K.,Li, H.,Hatzos-Skintges, C.,Bearden, J.,Babnigg, G.,Joachimiak, A. GH1-family 6-P-beta-glucosidases from human microbiome lactic acid bacteria. Acta Crystallogr.,Sect.D 2013 69 451 463
4D94 23055931 Crystal Structure of TEP1r 2012-01-11 2012-10-17 Le, B.V.,Williams, M.,Logarajah, S.,Baxter, R.H. Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles. Plos Pathog. 2012 8 0 0
4DRS 23056503 Crystal structure of Cryptosporidium parvum pyruvate kinase 2012-02-17 2012-10-17 Cook, W.J.,Senkovich, O.,Aleem, K.,Chattopadhyay, D. Crystal structure of Cryptosporidium parvum pyruvate kinase. Plos One 2012 7 0 0
4HBZ The Structure of Putative Phosphohistidine Phosphatase SixA from Nakamurella multipartitia. 2012-09-28 2012-10-17 Cuff, M.E.,Holowicki, J.,Endres, M.,Joachimiak, A. The Structure of Putative Phosphohistidine Phosphatase SixA from Nakamurella multipartitia. TO BE PUBLISHED 0 0 0 0
4HCI Uncharacterized Cupredoxin-like Domain Protein Cupredoxin_1 from Bacillus anthracis 2012-09-30 2012-10-17 Kim, Y.,Maltseva, N.,Shatsman, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Uncharacterized Cupredoxin-like Domain Protein Cupredoxin_1 from Bacillus anthracis To be Published 0 0 0 0
4HES Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula. 2012-10-04 2012-10-17 Cuff, M.E.,Li, H.,Clancy, S.,Joachimiak, A. Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula. TO BE PUBLISHED 0 0 0 0
4HDK 23039029 Crystal Structure of ArsAB in Complex with Phloroglucinol 2012-10-02 2012-10-24 Newmister, S.A.,Chan, C.H.,Escalante-Semerena, J.C.,Rayment, I. Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry 2012 51 8571 8582
4HDM 23039029 Crystal Structure of ArsAB in Complex with p-cresol 2012-10-02 2012-10-24 Newmister, S.A.,Chan, C.H.,Escalante-Semerena, J.C.,Rayment, I. Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry 2012 51 8571 8582
4HDN 23039029 Crystal Structure of ArsAB in the Substrate-Free State. 2012-10-02 2012-10-24 Newmister, S.A.,Chan, C.H.,Escalante-Semerena, J.C.,Rayment, I. Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry 2012 51 8571 8582
4HDR 23039029 Crystal Structure of ArsAB in Complex with 5,6-dimethylbenzimidazole 2012-10-02 2012-10-24 Newmister, S.A.,Chan, C.H.,Escalante-Semerena, J.C.,Rayment, I. Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry 2012 51 8571 8582
4GE2 23075115 Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3 2012-08-01 2012-10-31 Zhang, S.,Liu, S.,Tao, R.,Wei, D.,Chen, L.,Shen, W.,Yu, Z.H.,Wang, L.,Jones, D.R.,Dong, X.C.,Zhang, Z.Y. A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. J.Am.Chem.Soc. 2012 134 18116 18124
4GE5 23075115 Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 5 2012-08-01 2012-10-31 Zhang, S.,Liu, S.,Tao, R.,Wei, D.,Chen, L.,Shen, W.,Yu, Z.H.,Wang, L.,Jones, D.R.,Dong, X.C.,Zhang, Z.Y. A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. J.Am.Chem.Soc. 2012 134 18116 18124
4GE6 23075115 Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7 2012-08-01 2012-10-31 Zhang, S.,Liu, S.,Tao, R.,Wei, D.,Chen, L.,Shen, W.,Yu, Z.H.,Wang, L.,Jones, D.R.,Dong, X.C.,Zhang, Z.Y. A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. J.Am.Chem.Soc. 2012 134 18116 18124
4GHC 23066739 Structure of Y257F variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.55 Ang resolution 2012-08-07 2012-10-31 Kovaleva, E.G.,Lipscomb, J.D. Structural basis for the role of tyrosine 257 of homoprotocatechuate 2,3-dioxygenase in substrate and oxygen activation. Biochemistry 2012 51 8755 8763
4HAJ Crystal structure of PpcA K9E mutant 2012-09-26 2012-10-31 Pokkuluri, P.R.,Schiffer, M. Lysine mutants of PpcA To be Published 0 0 0 0
4HB6 Crystal structure of PpcA K22E mutant 2012-09-27 2012-10-31 Pokkuluri, P.R.,Schiffer, M. Lysine mutants of PpcA To be Published 0 0 0 0
4HB8 Crystal structure of PpcA K22Q mutant 2012-09-27 2012-10-31 Pokkuluri, P.R.,Schiffer, M. Lysine mutants of PpcA To be Published 0 0 0 0
4HBF Crystal structure of PpcA V13A mutant 2012-09-27 2012-10-31 Pokkuluri, P.R.,Schiffer, M. V13 mutants of PpcA To be Published 0 0 0 0
4HC3 Crystal structure of PpcA V13T mutant 2012-09-28 2012-10-31 Pokkuluri, P.R.,Schiffer, M. V13 mutants of PpcA To be Published 0 0 0 0
4HDL Crystal structure of PpcA F15L mutant 2012-10-02 2012-10-31 Pokkuluri, P.R.,Schiffer, M. F15L mutant of PpcA To be Published 0 0 0 0
3UMT scFv12, Anti-BclA antibody single chain variable fragment 2011-11-14 2012-11-14 Wilton, R.,Londer, Y.Y.,Hanson, D.K.,Zerbs, S.,Dirks, A.,Warner, C.,Carney, J.P.,Pokkuluri, P.R.,Stevens, F.J. Systematic stability engineering of single-chain antibodies To be Published 0 0 0 0
4HTL Lmo2764 protein, a putative N-acetylmannosamine kinase, from Listeria monocytogenes 2012-11-01 2012-11-14 Osipiuk, J.,Mack, J.,Endres, M.,Salazar, J.,Zhang, W.,Joachimiak, A. Lmo2764 protein, a putative N-acetylmannosamine kinase, from Listeria monocytogenes. To be Published 0 0 0 0
4HN0 23116432 Crystal Structure of ChmJ, a 3'-monoepimerase apoenzyme from Streptomyces bikiniensis 2012-10-18 2012-11-21 Kubiak, R.L.,Phillips, R.K.,Zmudka, M.W.,Ahn, M.R.,Maka, E.M.,Pyeatt, G.L.,Roggensack, S.J.,Holden, H.M. Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose. Biochemistry 2012 51 9375 9383
4HN1 23116432 Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP 2012-10-18 2012-11-21 Kubiak, R.L.,Phillips, R.K.,Zmudka, M.W.,Ahn, M.R.,Maka, E.M.,Pyeatt, G.L.,Roggensack, S.J.,Holden, H.M. Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose. Biochemistry 2012 51 9375 9383
4IIN Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+ 2012-12-20 2013-01-09 Hou, J.,Osinski, T.,Zheng, H.,Shumilin, I.,Shabalin, I.,Shatsman, S.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+ To be Published 0 0 0 0
4IIU Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Escherichia coli strain CFT073 complexed with NADP+ at 2.1 A resolution 2012-12-20 2013-01-09 Hou, J.,Osinski, T.,Zheng, H.,Shumilin, I.,Shabalin, I.,Shatsman, S.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Escherichia coli strain CFT073 complexed with NADP+ at 2.1 A resolution To be Published 0 0 0 0
4IC1 24171432 Crystal structure of SSO0001 2012-12-09 2013-01-16 Lemak, S.,Beloglazova, N.,Nocek, B.,Skarina, T.,Flick, R.,Brown, G.,Popovic, A.,Joachimiak, A.,Savchenko, A.,Yakunin, A.F. Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus. J.Am.Chem.Soc. 2013 135 17476 17487
4IC1 24171432 Crystal structure of SSO0001 2012-12-09 2013-01-16 Lemak, S.,Beloglazova, N.,Nocek, B.,Skarina, T.,Flick, R.,Brown, G.,Popovic, A.,Joachimiak, A.,Savchenko, A.,Yakunin, A.F. Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus. J.Am.Chem.Soc. 2013 135 17476 17487
4HUT 23148601 Structure of ATP:co(I)rrinoid adenosyltransferase (CobA) from Salmonella enterica in complex with four and five-coordinate cob(II)alamin and ATP 2012-11-04 2013-01-23 Moore, T.C.,Newmister, S.A.,Rayment, I.,Escalante-Semerena, J.C. Structural Insights into the Mechanism of Four-Coordinate Cob(II)alamin Formation in the Active Site of the Salmonella enterica ATP:Co(I)rrinoid Adenosyltransferase Enzyme: Critical Role of Residues Phe91 and Trp93. Biochemistry 2012 51 9647 9657
4IQE Crystal Structure of Carboxyvinyl-Carboxyphosphonate Phosphorylmutase from Bacillus anthracis str. Ames Ancestor 2013-01-11 2013-01-23 Kim, Y.,Maltseva, N.,Kwon, K.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Carboxyvinyl-Carboxyphosphonate Phosphorylmutase from Bacillus anthracis str. Ames Ancestor To be Published 0 0 0 0
4IQF Crystal Structure of Methyionyl-tRNA Formyltransferase from Bacillus anthracis 2013-01-11 2013-01-23 Kim, Y.,Makowska-Grzyska, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Methyionyl-tRNA Formyltransferase from Bacillus anthracis To be Published 0 0 0 0
4IQI Crystal Structure of 7-cyano-7-deazaguanine Reductase, QueF from Vibrio cholerae O1 biovar El Tor complexed with cytosine 2013-01-11 2013-01-23 Kim, Y.,Zhou, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of 7-cyano-7-deazaguanine Reductase, QueF from Vibrio cholerae O1 biovar El Tor complexed with cytosine To be Published 0 0 0 0
4IAG 26512730 Crystal structure of ZbmA, the zorbamycin binding protein from Streptomyces flavoviridis 2012-12-06 2013-02-20 Rudolf, J.D.,Bigelow, L.,Chang, C.,Cuff, M.E.,Lohman, J.R.,Chang, C.Y.,Ma, M.,Yang, D.,Clancy, S.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B. Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry 2015 54 6842 6851
4DGP 23457302 The wild-type Src homology 2 (SH2)-domain containing protein tyrosine phosphatase-2 (SHP2) 2012-01-26 2013-03-06 Yu, Z.H.,Xu, J.,Walls, C.D.,Chen, L.,Zhang, S.,Zhang, R.,Wu, L.,Wang, L.,Liu, S.,Zhang, Z.Y. Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations. J.Biol.Chem. 2013 288 10472 10482
4DGX 23457302 LEOPARD Syndrome-Associated SHP2/Y279C mutant 2012-01-27 2013-03-06 Yu, Z.H.,Xu, J.,Walls, C.D.,Chen, L.,Zhang, S.,Zhang, R.,Wu, L.,Wang, L.,Liu, S.,Zhang, Z.Y. Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations. J.Biol.Chem. 2013 288 10472 10482
4JJZ 22109967 Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ADP and Formylphosphate 2013-03-08 2013-03-20 Celeste, L.R.,Chai, G.,Bielak, M.,Minor, W.,Lovelace, L.L.,Lebioda, L. Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci. 2012 21 219 228
4IOM 23533144 N10-formyltetrahydrofolate synthetase from Moorella thermoacetica with folate 2013-01-08 2013-04-10 Stec, B. Time passes yet errors remain: Comments on the structure of N(10) -formyltetrahydrofolate synthetase. Protein Sci. 2013 22 671 674
4EUP The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide 2012-04-25 2013-05-01 Hossain, M.,Baker, B.M. Structural description of how different MART-1 antigenic peptides influence JKF6 T cell receptor recognition To be Published 0 0 0 0
4JGR 23436677 The crystal structure of sporulation kinase D mutant sensor domain, R131A, from Bacillus subtilis subsp at 2.4A resolution 2013-03-01 2013-05-15 Wu, R.,Gu, M.,Wilton, R.,Babnigg, G.,Kim, Y.,Pokkuluri, P.R.,Szurmant, H.,Joachimiak, A.,Schiffer, M. Insight into the sporulation phosphorelay: Crystal structure of the sensor domain of Bacillus subtilis histidine kinase, KinD. Protein Sci. 2013 22 564 576
4KCF 23621882 X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose 2013-04-24 2013-05-22 Thoden, J.B.,Branch, M.C.,Zimmer, A.L.,Bruender, N.A.,Holden, H.M. Active site architecture of a sugar N-oxygenase. Biochemistry 2013 52 3191 3193
4JYJ Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 2013-03-29 2013-05-29 Cooper, D.R.,Porebski, P.J.,Domagalski, M.J.,Ahmed, M.,Stead, M.,Hillerich, B.,Seidel, R.,Zimmerman, M.,Bonanno, J.B.,Almo, S.C.,Minor, W.,New York Structural Genomics Research Consortium (NYSGRC) Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 To be Published 0 0 0 0
4KOS 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefmetazole 2013-05-12 2013-06-05 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem. 2013 288 30223 30235
4KOV 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefuroxime 2013-05-12 2013-06-05 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem. 2013 288 30223 30235
4KOW 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefoxitin 2013-05-12 2013-06-05 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem. 2013 288 30223 30235
4KOX 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin 2013-05-12 2013-06-05 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA. J.Biol.Chem. 2013 288 30223 30235
4KUB 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA 2013-05-21 2013-06-05 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J.Biol.Chem. 2013 288 30223 30235
4K0D 23897711 Periplasmic sensor domain of sensor histidine kinase, Adeh_2942 2013-04-03 2013-06-12 Pokkuluri, P.R.,Dwulit-Smith, J.,Duke, N.E.,Wilton, R.,Mack, J.C.,Bearden, J.,Rakowski, E.,Babnigg, G.,Szurmant, H.,Joachimiak, A.,Schiffer, M. Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein. Microbiologyopen 2013 2 766 777
4KVH Crystal structure of ketosteroid isomerase fold protein Hmuk_0747 2013-05-22 2013-06-12 Chang, C.,Holowicki, J.,Bearden, J.,Joachimiak, A. Crystal structure of ketosteroid isomerase fold protein Hmuk_0747 To be Published 0 0 0 0
4FO7 Pseudomonas aeruginosa MetAP, in Mn form 2012-06-20 2013-07-03 Lu, J.P.,Ye, Q.Z. Methionine excision captured by the structures of a methionine aminopeptidase To be published 0 0 0 0
4FO8 Pseudomonas aeruginosa MetAP with Met, in Mn form 2012-06-20 2013-07-03 Lu, J.P.,Ye, Q.Z. Methionine excision captured by the structures of a methionine aminopeptidase To be published 0 0 0 0
4FTV The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide 2012-06-28 2013-07-03 Borbulevych, O.Y.,Baker, B.M. Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity To be Published 0 0 0 0
4L89 24003232 Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with covalently bound CoA 2013-06-16 2013-07-10 Majorek, K.A.,Kuhn, M.L.,Chruszcz, M.,Anderson, W.F.,Minor, W. Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J.Biol.Chem. 2013 288 30223 30235
4K08 23897711 Periplasmic sensor domain of chemotaxis protein, Adeh_3718 2013-04-03 2013-07-17 Pokkuluri, P.R.,Dwulit-Smith, J.,Duke, N.E.,Wilton, R.,Mack, J.C.,Bearden, J.,Rakowski, E.,Babnigg, G.,Szurmant, H.,Joachimiak, A.,Schiffer, M. Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein. Microbiologyopen 2013 2 766 777
4J51 23713581 Cyrstal structure of protein tyrosine phosphatase Lyp catalytic domain complex with small molecular inhibitor L75N04 2013-02-07 2013-07-24 He, Y.,Liu, S.,Menon, A.,Stanford, S.,Oppong, E.,Gunawan, A.M.,Wu, L.,Wu, D.J.,Barrios, A.M.,Bottini, N.,Cato, A.C.,Zhang, Z.Y. A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune Diseases. J.Med.Chem. 2013 56 4990 5008
4KM7 23934049 Human folate receptor alpha (FOLR1) at acidic pH, triclinic form 2013-05-08 2013-08-07 Wibowo, A.S.,Singh, M.,Reeder, K.M.,Carter, J.J.,Kovach, A.R.,Meng, W.,Ratnam, M.,Zhang, F.,Dann, C.E. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA 2013 110 15180 15188
4LXQ 23898784 Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp and 5-N-Formyl-THF 2013-07-30 2013-08-14 Thoden, J.B.,Goneau, M.F.,Gilbert, M.,Holden, H.M. Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry 2013 52 6114 6126
4LXT 23898784 Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp-Qui3N and 5-N-Formyl-THF 2013-07-30 2013-08-14 Thoden, J.B.,Goneau, M.F.,Gilbert, M.,Holden, H.M. Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry 2013 52 6114 6126
4LXU 23898784 dTdp-Fuc3N and 5-N-Formyl-THF 2013-07-30 2013-08-14 Thoden, J.B.,Goneau, M.F.,Gilbert, M.,Holden, H.M. Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry 2013 52 6114 6126
4LXX 23898784 Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Fuc3NFo and 5-N-Formyl-THF 2013-07-30 2013-08-14 Thoden, J.B.,Goneau, M.F.,Gilbert, M.,Holden, H.M. Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry 2013 52 6114 6126
4MA0 The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP 2013-08-15 2013-08-28 Tan, K.,Zhou, M.,Kwon, K.,Anderson, W.F.,Joachimiak, A. The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP To be Published 0 0 0 0
4MLZ Crystal structure of periplasmic binding protein from Jonesia denitrificans 2013-09-06 2013-09-18 Chang, C.,Chhor, G.,Endres, M.,Joachimiak, A. Crystal structure of periplasmic binding protein from Jonesia denitrificans To be Published 0 0 0 0
4HE1 24086250 Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate 2012-10-03 2013-10-09 Shi, R.,Chen, Z.Y.,Zhu, D.W.,Li, C.,Shan, Y.,Xu, G.,Lin, S.X. Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway. Plos One 2013 8 0 0
4MZU 24128043 Crystal structure of FdtD, a bifunctional ketoisomerase/N-acetyltransferase from Shewanella denitrificans 2013-09-30 2013-10-09 Chantigian, D.P.,Thoden, J.B.,Holden, H.M. Structural and Biochemical Characterization of a Bifunctional Ketoisomerase/N-Acetyltransferase from Shewanella denitrificans. Biochemistry 2013 52 8374 8385
4K07 24157440 Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant 2013-04-03 2013-10-30 Blancas-Mejia, L.M.,Tischer, A.,Thompson, J.R.,Tai, J.,Wang, L.,Auton, M.,Ramirez-Alvarado, M. Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations. J.Mol.Biol. 2014 426 347 361
4MGR 24127574 The crystal structure of Bacillus subtilis GabR, an autorepressor and PLP- and GABA-dependent transcriptional activator of gabT 2013-08-28 2013-10-30 Edayathumangalam, R.,Wu, R.,Garcia, R.,Wang, Y.,Wang, W.,Kreinbring, C.A.,Bach, A.,Liao, J.,Stone, T.A.,Terwilliger, T.C.,Hoang, Q.Q.,Belitsky, B.R.,Petsko, G.A.,Ringe, D.,Liu, D. Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proc.Natl.Acad.Sci.USA 2013 110 17820 17825
4N0B 24127574 Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of GabT 2013-10-01 2013-10-30 Edayathumangalam, R.,Wu, R.,Garcia, R.,Wang, Y.,Wang, W.,Kreinbring, C.A.,Bach, A.,Liao, J.,Stone, T.A.,Terwilliger, T.C.,Hoang, Q.Q.,Belitsky, B.R.,Petsko, G.A.,Ringe, D.,Liu, D. Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proc.Natl.Acad.Sci.USA 2013 110 17820 17825
4NCZ 25623305 Spermidine N-acetyltransferase from Vibrio cholerae in complex with 2-[n-cyclohexylamino]ethane sulfonate. 2013-10-25 2013-11-06 Filippova, E.V.,Kuhn, M.L.,Osipiuk, J.,Kiryukhina, O.,Joachimiak, A.,Ballicora, M.A.,Anderson, W.F. A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol. 2015 427 1316 1334
4NAS The crystal structure of a rubisco-like protein (MtnW) from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 2013-10-22 2013-11-13 Tan, K.,Li, H.,Clancy, S.,Joachimiak, A. The crystal structure of a rubisco-like protein (MtnW) from Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446. To be Published 0 0 0 0
4M9B 24253038 Crystal structure of Apo Ara h 8 2013-08-14 2013-11-27 Hurlburt, B.K.,Offermann, L.R.,McBride, J.K.,Majorek, K.A.,Maleki, S.J.,Chruszcz, M. Structure and Function of the Peanut Panallergen Ara h 8. J.Biol.Chem. 2013 288 36890 36901
4MAP 24253038 Crystal structure of Ara h 8 purified with heating 2013-08-16 2013-11-27 Hurlburt, B.K.,Offermann, L.R.,McBride, J.K.,Majorek, K.A.,Maleki, S.J.,Chruszcz, M. Structure and Function of the Peanut Panallergen Ara h 8. J.Biol.Chem. 2013 288 36890 36901
4NHE The crystal structure of oxidoreductase (Gfo/Idh/MocA family) from Streptococcus pneumoniae TIGR4 in complex with NADP 2013-11-04 2013-11-27 Tan, K.,Hatzos-Skintges, C.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of oxidoreductase (Gfo/Idh/MocA family) from Streptococcus pneumoniae TIGR4 in complex with NADP. To be Published 0 0 0 0
4NOC The crystal structure of a CBS Domain-containing Protein of Unknown Function from Kribbella flavida DSM 17836. 2013-11-19 2013-11-27 Tan, K.,Hatzos-Skintges, C.,Jedrzejczak, R.,Joachimiak, A. The crystal structure of a CBS Domain-containing Protein of Unknown Function from Kribbella flavida DSM 17836. To be Published 0 0 0 0
4NV1 24347283 Crystal structure of a 4-N formyltransferase from Francisella tularensis 2013-12-04 2013-12-25 Zimmer, A.L.,Thoden, J.B.,Holden, H.M. Three-dimensional structure of a sugar N-formyltransferase from Francisella tularensis. Protein Sci. 2014 23 273 283
4NNQ Crystal structure of LnmF protein from Streptomyces amphibiosporus 2013-11-18 2014-01-15 0 0 0 0
4NEO 25050442 Structure of BlmI, a type-II acyl-carrier-protein from Streptomyces verticillus involved in bleomycin biosynthesis 2013-10-29 2014-01-29 Lohman, J.R.,Ma, M.,Cuff, M.E.,Bigelow, L.,Bearden, J.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B. The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins. Proteins 2014 82 1210 1218
4OG1 Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 2014-01-15 2014-01-29 Chapman, H.C.,Cooper, D.R.,Tkaczuk, K.L.,Cymborowski, M.T.,Stead, M.,Hillerich, B.,Ahmed, M.,Bonanno, J.B.,Seidel, R.,Alkire, R.,Almo, S.C.,Minor, W. Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 To be Published 0 0 0 0
4I05 25456815 Structure of intermediate processing form of cathepsin B1 from Schistosoma mansoni 2012-11-16 2014-02-05 Jilkova, A.,Horn, M.,Rezacova, P.,Maresova, L.,Fajtova, P.,Brynda, J.,Vondrasek, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure 2014 22 1786 1798
4I07 25456815 Structure of mature form of cathepsin B1 from Schistosoma mansoni 2012-11-16 2014-02-05 Jilkova, A.,Horn, M.,Rezacova, P.,Maresova, L.,Fajtova, P.,Brynda, J.,Vondrasek, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure 2014 22 1786 1798
4OQD 24512254 Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Qui3NMe2 2014-02-08 2014-02-26 Thoden, J.B.,Holden, H.M. Production of a novel N-monomethylated dideoxysugar. Biochemistry 2014 53 1105 1107
4KQI 24121107 Crystal structure of CobT E317A complexed with its reaction products 2013-05-15 2014-03-12 Chan, C.H.,Newmister, S.A.,Talyor, K.,Claas, K.R.,Rayment, I.,Escalante-Semerena, J.C. Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica. Biochim.Biophys.Acta 2014 1840 464 475
4KQK 24121107 Crystal structure of CobT S80Y/Q88M/L175M complexed with p-cresol 2013-05-15 2014-03-12 Chan, C.H.,Newmister, S.A.,Talyor, K.,Claas, K.R.,Rayment, I.,Escalante-Semerena, J.C. Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica. Biochim.Biophys.Acta 2014 1840 464 475
4NAH 24041904 Inhibitors of 4-Phosphopanthetheine Adenylyltransferase (PPAT) 2013-10-22 2014-03-12 de Jonge, B.L.,Walkup, G.K.,Lahiri, S.D.,Huynh, H.,Neckermann, G.,Utley, L.,Nash, T.J.,Brock, J.,San Martin, M.,Kutschke, A.,Johnstone, M.,Laganas, V.,Hajec, L.,Gu, R.F.,Ni, H.,Chen, B.,Hutchings, K.,Holt, E.,McKinney, D.,Gao, N.,Livchak, S.,Thresher, J. Discovery of inhibitors of 4'-phosphopantetheine adenylyltransferase (PPAT) to validate PPAT as a target for antibacterial therapy. Antimicrob.Agents Chemother. 2013 57 6005 6015
4NAT 24041904 Inhibitors of 4-Phosphopanthetheine Adenylyltransferase 2013-10-22 2014-03-12 de Jonge, B.L.,Walkup, G.K.,Lahiri, S.D.,Huynh, H.,Neckermann, G.,Utley, L.,Nash, T.J.,Brock, J.,San Martin, M.,Kutschke, A.,Johnstone, M.,Laganas, V.,Hajec, L.,Gu, R.F.,Ni, H.,Chen, B.,Hutchings, K.,Holt, E.,McKinney, D.,Gao, N.,Livchak, S.,Thresher, J. Discovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy. Antimicrob.Agents Chemother. 2013 57 6005 6015
4OMR Crystal structure of Tfu_1878, a putative enoyl-CoA hydratase from Thermobifida fusca YX in complex with acetoacetyl-CoA 2014-01-27 2014-04-02 Langner, K.M.,Cooper, D.R.,Chapman, H.C.,Handing, K.B.,Stead, M.,Hillerich, B.,Ahmed, M.,Bonanno, J.B.,Seidel, R.,Almo, S.C.,Minor, W.,New York Structural Genomics Research Consortium (NYSGRC) Crystal structure of Tfu_1878, a putative enoyl-CoA hydratase from Thermobifida fusca YX in complex with acetoacetyl-CoA To be Published 0 0 0 0
4PV4 Proline aminopeptidase P II from Yersinia pestis 2014-03-14 2014-04-02 Osipiuk, J.,Maltseva, N.,Shatsman, S.,Anderson, W.F.,Joachimiak, A. Proline aminopeptidase P II from Yersinia pestis To be Published 0 0 0 0
4PZK Crystal strucrure of putative RNA methyltransferase from Bacillus anthracis. 2014-03-31 2014-04-16 Maltseva, N.,Kim, Y.,Shatsman, S.,Anderson, W.F.,Joachimiak, A. Crystal strucrure of putative RNA methyltransferase from Bacillus anthracis. To be Published 0 0 0 0
4JUQ Pseudomonas aeruginosa MetAP T2N mutant, in Mn form 2013-03-25 2014-04-30 Lu, J.P.,Ye, Q.Z. Methionine excision captured by the structures of a methionine aminopeptidase To be published 0 0 0 0
4M8X 24371077 GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits HIV PR Mutants with Amino Acid Insertions 2013-08-14 2014-05-07 Grantz Saskova, K.,Kozisek, M.,Stray, K.,de Jong, D.,Rezaova, P.,Brynda, J.,van Maarseveen, N.M.,Nijhuis, M.,Cihlar, T.,Konvalinka, J. GS-8374, a prototype phosphonate-containing inhibitor of HIV-1 protease, effectively inhibits protease mutants with amino acid insertions. J.Virol. 2014 88 3586 3590
4JRW 25760606 Crystal structure of Clostridium histolyticum colg collagenase PKD domain 2 at 1.6 Angstrom resolution 2013-03-22 2014-05-21 Bauer, R.,Janowska, K.,Taylor, K.,Jordan, B.,Gann, S.,Janowski, T.,Latimer, E.C.,Matsushita, O.,Sakon, J. Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH. Acta Crystallogr.,Sect.D 2015 71 565 577
4Q88 Glycosyl hydrolase family 88 from Bacteroides vulgatus 2014-04-25 2014-05-21 Osipiuk, J.,Li, H.,Endres, M.,Joachimiak, A. Glycosyl hydrolase Family 88 from Bacteroides vulgatus To be Published 0 0 0 0
4Q6W Crystal Structure of Periplasmic Binding Protein type 1 from Bordetella pertussis Tohama I complexed with 3-Hydroxy Benzoic Acid 2014-04-23 2014-07-02 Kim, Y.,Joachimiak, G.,Clancy, S.,Joachimiak, A. Crystal Structure of Periplasmic Binding Protein type 1 from Bordetella pertussis Tohama I complexed with 3-Hydroxy Benzoic Acid To be Published 2014 0 0 0
4ONR 24842928 Crystal structure of Borrelia burgdorferi decorin-binding protein DbpA 2014-01-28 2014-07-09 Fortune, D.E.,Lin, Y.P.,Deka, R.K.,Groshong, A.M.,Moore, B.P.,Hagman, K.E.,Leong, J.M.,Tomchick, D.R.,Blevins, J.S. Identification of Lysine Residues in the Borrelia burgdorferi DbpA Adhesin Required for Murine Infection. Infect.Immun. 2014 82 3186 3198
4U12 Crystal structure of protein HP0242 from Helicobacter pylori at 1.94 A resolution: a knotted homodimer 2014-07-14 2014-07-23 Grabowski, M.,Shabalin, I.G.,Chruszcz, M.,Skarina, T.,Onopriyenko, O.,Guthrie, J.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Minor, W. Crystal structure of protein HP0242 from Helicobacter pylori at 1.94 A resolution: a knotted homodimer to be published 0 0 0 0
4QNE Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with NAD and IMP 2014-06-17 2014-08-06 Osipiuk, J.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Anderson, W.F.,Joachimiak, A. Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with NAD and IMP To be Published 0 0 0 0
4MCM 25433341 Human SOD1 C57S Mutant, As-isolated 2013-08-21 2014-08-27 Sea, K.,Sohn, S.H.,Durazo, A.,Sheng, Y.,Shaw, B.F.,Cao, X.,Taylor, A.B.,Whitson, L.J.,Holloway, S.P.,Hart, P.J.,Cabelli, D.E.,Gralla, E.B.,Valentine, J.S. Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J.Biol.Chem. 2015 290 2405 2418
4R7R Crystal Structure of Putative Lipoprotein from Clostridium perfringens 2014-08-28 2014-09-10 Kim, Y.,Zhou, M.,Shatsman, S.,Anderson, W.F.,Joachimiak, A. Crystal Structure of Putative Lipoprotein from Clostridium perfringens To be Published 0 0 0 0
4W9T 26929404 Crystal structure of HisAP from Streptomyces sp. Mg1 2014-08-27 2014-09-10 Verduzco-Castro, E.A.,Michalska, K.,Endres, M.,Juarez-Vazquez, A.L.,Noda-Garcia, L.,Chang, C.,Henry, C.S.,Babnigg, G.,Joachimiak, A.,Barona-Gomez, F. Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J. 2016 473 1141 1152
4R9X Crystal Structure of Putative Copper Homeostasis Protein CutC from Bacillus anthracis 2014-09-08 2014-09-17 Kim, Y.,Zhou, M.,Makowska-Grzyska, M.,Grimshaw, S.,Anderson, W.F.,Joachimiak, A.,CSGID Crystal Structure of Putative Copper Homeostasis Protein CutC from Bacillus anthracis To be Published 2014 0 0 0
4OHD 24935154 LEOPARD Syndrome-Associated SHP2/A461T mutant 2014-01-17 2014-09-24 Yu, Z.H.,Zhang, R.Y.,Walls, C.D.,Chen, L.,Zhang, S.,Wu, L.,Liu, S.,Zhang, Z.Y. Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry 2014 53 4136 4151
4OHL 24935154 LEOPARD Syndrome-Associated SHP2/T468M mutant 2014-01-17 2014-09-24 Yu, Z.H.,Zhang, R.Y.,Walls, C.D.,Chen, L.,Zhang, S.,Wu, L.,Liu, S.,Zhang, Z.Y. Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry 2014 53 4136 4151
4WHI Crystal structure of C-terminal domain of penicillin binding protein Rv0907 2014-09-22 2014-10-08 Chang, C.,Hatzos-Skintges, C.,Jedrzejczak, R.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of C-terminal domain of penicillin binding protein Rv0907 To Be Published 0 0 0 0
4W8I 26831115 Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase 2014-08-24 2014-11-05 Rolando, M.,Escoll, P.,Nora, T.,Botti, J.,Boitez, V.,Bedia, C.,Daniels, C.,Abraham, G.,Stogios, P.J.,Skarina, T.,Christophe, C.,Dervins-Ravault, D.,Cazalet, C.,Hilbi, H.,Rupasinghe, T.W.,Tull, D.,McConville, M.J.,Ong, S.Y.,Hartland, E.L.,Codogno, P.,Levade, T.,Naderer, T.,Savchenko, A.,Buchrieser, C. Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc.Natl.Acad.Sci.USA 2016 113 1901 1906
4PMH 25372813 The structure of rice weevil pectin methyl esterase 2014-05-21 2014-11-12 Teller, D.C.,Behnke, C.A.,Pappan, K.,Shen, Z.,Reese, J.C.,Reeck, G.R.,Stenkamp, R.E. The structure of rice weevil pectin methylesterase. Acta Crystallogr.,Sect.F 2014 70 1480 1484
4RQO 25380533 Crystal structure of L-Serine Dehydratase from Legionella pneumophila 2014-11-04 2014-11-19 Thoden, J.B.,Holden, H.M.,Grant, G.A. Structure of l-Serine Dehydratase from Legionella pneumophila: Novel Use of the C-Terminal Cysteine as an Intrinsic Competitive Inhibitor. Biochemistry 2014 53 7615 7624
4U5Y 25381442 Crystal Structure of the complex between the GNAT domain of S. lividans PAT and the acetyl-CoA synthetase C-terminal domain of S. enterica 2014-07-25 2014-11-19 Tucker, A.C.,Taylor, K.C.,Rank, K.C.,Rayment, I.,Escalante-Semerena, J.C. Insights into the specificity of lysine acetyltransferases. J.Biol.Chem. 2014 289 36249 36262
4RU0 The crystal structure of abc transporter permease from pseudomonas fluorescens group 2014-11-17 2014-11-26 Wu, R.,Endres, M.,Joachimiak, A. The crystal structure of abc transporter permease from pseudomonas fluorescens group To be Published 0 0 0 0
4WCZ Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans 2014-09-05 2014-12-03 Tkaczuk, K.L.,Cooper, D.R.,Chapman, H.C.,Niedzialkowska, E.,Cymborowski, M.T.,Hillerich, B.S.,Stead, M.,Ahmed, M.,Hammonds, J.,Bonanno, J.,Seidel, R.,Almo, S.C.,Minor, W.,New York Structural Genomics Research Consortium (NYSGRC) Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans to be published 0 0 0 0
4ND2 25542170 Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide) 2013-10-25 2014-12-17 Cook, W.J.,Senkovich, O.,Hernandez, A.,Speed, H.,Chattopadhyay, D. Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol. 2014 0 608 619
4ND3 25542170 Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 2013-10-25 2014-12-17 Cook, W.J.,Senkovich, O.,Hernandez, A.,Speed, H.,Chattopadhyay, D. Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol. 2014 0 608 619
4ND4 25542170 Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor (b-nicotinamide adenine dinucleotide) 2013-10-25 2014-12-17 Cook, W.J.,Senkovich, O.,Hernandez, A.,Speed, H.,Chattopadhyay, D. Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol. 2014 0 608 619
4RGP Crystal Structure of Uncharacterized CRISPR/Cas System-associated Protein Csm6 from Streptococcus mutans 2014-09-30 2014-12-24 Kim, Y.,Li, H.,Clancy, S.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal Structure of Uncharacterized CRISPR/Cas System-associated Protein Csm6 from Streptococcus mutans To be Published 0 0 0 0
4X9P 25772737 Crystal structure of bovine Annexin A2 2014-12-11 2015-01-14 Raddum, A.M.,Hollas, H.,Shumilin, I.A.,Henklein, P.,Kretsinger, R.,Fossen, T.,Vedeler, A. The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects. Biochem. Pharmacol. 2015 95 1 15
4XLT Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 2015-01-13 2015-01-28 Chang, C.,Cuff, M.,Holowicki, J.,Clancy, S.,Joachimiak, A. Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 To Be Published 0 0 0 0
4XOX Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae 2015-01-16 2015-01-28 Hou, J.,Grabowski, M.,Cymborowski, M.,Zheng, H.,Cooper, D.R.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae to be published 0 0 0 0
4WPN 25634381 Structure of human ALDH1A1 with inhibitor CM053 2014-10-20 2015-02-11 Morgan, C.A.,Hurley, T.D. Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors. J.Med.Chem. 2015 58 1964 1975
4XRR 26240141 Crystal structure of cals8 from micromonospora echinospora (P294S mutant) 2015-01-21 2015-02-11 Singh, S.,Michalska, K.,Bigelow, L.,Endres, M.,Kharel, M.K.,Babnigg, G.,Yennamalli, R.M.,Bingman, C.A.,Joachimiak, A.,Thorson, J.S.,Phillips, G.N. Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. J. Biol. Chem. 2015 290 26249 26258
4XXT Crystal structure of Fused Zn-dependent amidase/peptidase/peptodoglycan-binding domain-containing protein from Clostridium acetobutylicum ATCC 824 2015-01-30 2015-02-18 Chang, C.,Cuff, M.,Joachimiak, G.,Endres, M.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of Fused Zn-dependent amidase/peptidase/peptodoglycan-binding domain-containing protein from from Clostridium acetobutylicum ATCC 824 To Be Published 0 0 0 0
4Y7D Alpha/beta hydrolase fold protein from Nakamurella multipartita 2015-02-14 2015-02-25 Cuff, M.E.,OSIPIUK, J.,Holowicki, J.,Endres, M.,Joachimiak, A. Alpha/beta hydrolase fold protein from Nakamurella multipartita. to be published 0 0 0 0
4RGU Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with ferulic acid 2014-09-30 2015-03-04 Kim, Y.,Joachimiak, G.,Bigelow, L.,Cobb, G.,Joachimiak, A. Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with ferulic acid To be Published 2014 0 0 0
4WRP The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2014-10-24 2015-03-18 Cuff, M.E.,Evdokimova, E.,Egorova, O.,Savchenko, A.,Edwards, A.,Joachimiak, A. The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1. To Be Published 0 0 0 0
4RLR 25786707 Structure of monoheme cytochrome PccH from Geobacter sulfurreducens 2014-10-17 2015-04-01 Dantas, J.M.,Campelo, L.M.,Duke, N.E.,Salgueiro, C.A.,Pokkuluri, P.R. The structure of PccH from Geobacter sulfurreducens - a novel low reduction potential monoheme cytochrome essential for accepting electrons from an electrode. Febs J. 2015 282 2215 2231
4POZ 26026055 Fab fragment of Der p 1 specific antibody 10B9 2014-02-26 2015-04-08 Osinski, T.,Pomes, A.,Majorek, K.A.,Glesner, J.,Offermann, L.R.,Vailes, L.D.,Chapman, M.D.,Minor, W.,Chruszcz, M. Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies. J. Immunol. 2015 195 307 316
4RXV 27986836 The crystal structure of the N-terminal fragment of uncharacterized protein from Legionella pneumophila 2014-12-12 2015-04-08 Urbanus, M.L.,Quaile, A.T.,Stogios, P.J.,Morar, M.,Rao, C.,Di Leo, R.,Evdokimova, E.,Lam, M.,Oatway, C.,Cuff, M.E.,Osipiuk, J.,Michalska, K.,Nocek, B.P.,Taipale, M.,Savchenko, A.,Ensminger, A.W. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol 2016 12 893 893
4RXV 27986836 The crystal structure of the N-terminal fragment of uncharacterized protein from Legionella pneumophila 2014-12-12 2015-04-08 Urbanus, M.L.,Quaile, A.T.,Stogios, P.J.,Morar, M.,Rao, C.,Di Leo, R.,Evdokimova, E.,Lam, M.,Oatway, C.,Cuff, M.E.,Osipiuk, J.,Michalska, K.,Nocek, B.P.,Taipale, M.,Savchenko, A.,Ensminger, A.W. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol 2016 12 893 893
4PVG Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79 2014-03-17 2015-04-15 Zhang, Z.-Y.,Zeng, L.,Liu, D.,Yu, Z. Crystal structure of protein tyrosine Shp2 catalytic domain complex with compound L88N79 To be Published 0 0 0 0
4Q50 26836308 The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen 2014-04-15 2015-04-15 Fanning, S.W.,Mayne, C.G.,Dharmarajan, V.,Carlson, K.E.,Martin, T.A.,Novick, S.J.,Toy, W.,Green, B.,Panchamukhi, S.,Katzenellenbogen, B.S.,Tajkhorshid, E.,Griffin, P.R.,Shen, Y.,Chandarlapaty, S.,Katzenellenbogen, J.A.,Greene, G.L. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife 2016 5 0 0
4RXI 27986836 Structure of C-terminal domain of uncharacterized protein from Legionella pneumophila 2014-12-11 2015-05-06 Urbanus, M.L.,Quaile, A.T.,Stogios, P.J.,Morar, M.,Rao, C.,Di Leo, R.,Evdokimova, E.,Lam, M.,Oatway, C.,Cuff, M.E.,Osipiuk, J.,Michalska, K.,Nocek, B.P.,Taipale, M.,Savchenko, A.,Ensminger, A.W. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol 2016 12 893 893
4RXI 27986836 Structure of C-terminal domain of uncharacterized protein from Legionella pneumophila 2014-12-11 2015-05-06 Urbanus, M.L.,Quaile, A.T.,Stogios, P.J.,Morar, M.,Rao, C.,Di Leo, R.,Evdokimova, E.,Lam, M.,Oatway, C.,Cuff, M.E.,Osipiuk, J.,Michalska, K.,Nocek, B.P.,Taipale, M.,Savchenko, A.,Ensminger, A.W. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol 2016 12 893 893
4XO0 25961938 Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex 2015-01-16 2015-05-27 Georgiadis, M.M.,Singh, I.,Kellett, W.F.,Hoshika, S.,Benner, S.A.,Richards, N.G. Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc. 2015 137 6947 6955
4ZM8 20545851 Crystal Structure of Sialostatin L 2015-05-02 2015-06-17 Kotsyfakis, M.,Horka, H.,Salat, J.,Andersen, J.F. The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Mol. Microbiol. 2010 77 456 470
4ZQR 26440283 Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis 2015-05-11 2015-06-17 Makowska-Grzyska, M.,Kim, Y.,Gorla, S.K.,Wei, Y.,Mandapati, K.,Zhang, M.,Maltseva, N.,Modi, G.,Boshoff, H.I.,Gu, M.,Aldrich, C.,Cuny, G.D.,Hedstrom, L.,Joachimiak, A. Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. Plos One 2015 10 0 0
4RDD 26191366 Co-crystal structure of SHP2 in complex with a Cefsulodin derivative 2014-09-18 2015-07-01 He, R.,Yu, Z.H.,Zhang, R.Y.,Wu, L.,Gunawan, A.M.,Lane, B.S.,Shim, J.S.,Zeng, L.F.,He, Y.,Chen, L.,Wells, C.D.,Liu, J.O.,Zhang, Z.Y. Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. ACS Med Chem Lett 2015 6 782 786
4XA6 26150528 Crystal Structure of the coiled-coil surrounding Skip 4 of MYH7 2014-12-12 2015-07-01 Taylor, K.C.,Buvoli, M.,Korkmaz, E.N.,Buvoli, A.,Zheng, Y.,Heinze, N.T.,Cui, Q.,Leinwand, L.A.,Rayment, I. Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly. Proc.Natl.Acad.Sci.USA 2015 112 0 0
4ZO3 26115006 AidC, a Dizinc Quorum-Quenching Lactonase, in complex with a product N-hexnoyl-L-homoserine 2015-05-05 2015-07-15 Mascarenhas, R.,Thomas, P.W.,Wu, C.X.,Nocek, B.P.,Hoang, Q.Q.,Liu, D.,Fast, W. Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity. Biochemistry 2015 54 4342 4353
5CNP 26410587 X-ray crystal structure of Spermidine n1-acetyltransferase from Vibrio cholerae. 2015-07-17 2015-07-29 Filippova, E.V.,Weigand, S.,Osipiuk, J.,Kiryukhina, O.,Joachimiak, A.,Anderson, W.F. Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG. J.Mol.Biol. 2015 427 3538 3553
5CMN 26235030 FLRT3 LRR domain in complex with LPHN3 Olfactomedin domain 2015-07-17 2015-08-12 Lu, Y.C.,Nazarko, O.V.,Sando, R.,Salzman, G.S.,Sudhof, T.C.,Arac, D. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure 2015 23 1678 1691
5CB8 26294763 Crystal structure of Adenosine-5'-phosphosulfate kinase in complex with APS and sulfate 2015-06-30 2015-09-02 Herrmann, J.,Nathin, D.,Lee, S.G.,Sun, T.,Jez, J.M. Recapitulating the Structural Evolution of Redox Regulation in Adenosine 5'-Phosphosulfate Kinase from Cyanobacteria to Plants. J.Biol.Chem. 2015 290 24705 24714
4NKQ 27396825 Structure of a Cytokine Receptor Complex 2013-11-13 2015-09-23 Broughton, S.E.,Hercus, T.R.,Nero, T.L.,Dottore, M.,McClure, B.J.,Dhagat, U.,Taing, H.,Gorman, M.A.,King-Scott, J.,Lopez, A.F.,Parker, M.W. Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure 2016 24 1271 1281
5A23 SdsA sulfatase triclinic form 2015-05-11 2015-10-07 De La Mora, E.,Flores-Hernandez, E.,Jakoncic, J.,Stojanoff, V.,Siliqi, D.,Sanchez-Puig, N.,Moreno, A. Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques J.Appl.Crystallogr. 2015 48 1551 0
4WOJ Aspartate Semialdehyde Dehydrogenase from Francisella tularensis 2014-10-15 2015-10-21 Mank, N.J.,Pote, S.,Majorek, K.A.,Arnette, A.K.,Klapper, V.G.,Hurlburt, B.K.,Chruszcz, M. Structure of aspartate b-semialdehyde dehydrogenase from Francisella tularensis Acta Crystallogr.,Sect.F 2018 74 14 22
5END 26553852 Crystal structure of beta-ketoacyl-acyl carrier protein reductase (FabG)(Q152A) from Vibrio cholerae 2015-11-09 2015-12-23 Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W. Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol. 2015 198 463 476
5F9M Crystal structure of native B3275, member of MccF family of enzymes 2015-12-09 2015-12-30 Nocek, B.,Severinov, K.,Anderson, W.F.,Joachimiak, A. Crystal structure of native B3275, member of MccF family of enzymes. To Be Published 0 0 0 0
5FFM 16051820 Yellow fever virus helicase 2015-12-18 2015-12-30 Wu, J.,Bera, A.K.,Kuhn, R.J.,Smith, J.L. Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing. J. Virol. 2005 79 10268 10277
4V3F 26792760 Crystal structure of betaine aldehyde dehydrogenase from spinach showing a thiohemiacetal with betaine aldehyde 2014-10-18 2016-01-20 Zarate-Romero, A.,Murillo-Melo, D.S.,Mujica-Jimenez, C.,Montiel, C.,Munoz-Clares, R.A. Reversible, Partial Inactivation of Plant Betaine Aldehyde Dehydrogenase by Betaine Aldehyde: Mechanism and Possible Physiological Implications. Biochem.J. 2016 473 873 0
4YHP 26862167 Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide 2015-02-27 2016-02-10 Hattori, T.,Lai, D.,Dementieva, I.S.,Montano, S.P.,Kurosawa, K.,Zheng, Y.,Akin, L.R.,Swist-Rosowska, K.M.,Grzybowski, A.T.,Koide, A.,Krajewski, K.,Strahl, B.D.,Kelleher, N.L.,Ruthenburg, A.J.,Koide, S. Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc.Natl.Acad.Sci.USA 2016 113 2092 2097
5HX0 Crystal structure of unknown function protein Dfer_1899 fromDyadobacter fermentans DSM 18053 2016-01-29 2016-02-17 Chang, C.,Duke, N.,Clancy, S.,Chhor, G.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of unknown function protein Dfer_1899 fromDyadobacter fermentans DSM 18053 To Be Published 0 0 0 0
5I4K Metal ABC transporter from Listeria monocytogenes with manganese 2016-02-12 2016-02-24 Osipiuk, J.,Zhou, M.,Grimshaw, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Metal ABC transporter from Listeria monocytogenes with manganese to be published 0 0 0 0
5I47 Crystal structure of RimK domain protein ATP-grasp from Sphaerobacter thermophilus DSM 20745 2016-02-11 2016-03-16 Chang, C.,Duke, N.,Wu, R.,Clancy, S.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of RimK domain protein ATP-grasp from Sphaerobacter thermophilus DSM 20745 To Be Published 0 0 0 0
5IXP Crystal structure of Extracellular solute-binding protein family 1 2016-03-23 2016-03-30 Chang, C.,Cuff, M.,Chhor, G.,Endres, M.,Joachimiak, A. Crystal structure of Extracellular solute-binding protein family 1 To Be Published 0 0 0 0
4Z5Z The 2.5-angstrom crystal structure of Mg(2+)-bound PqqB from Pseudomonas Putida 2015-04-03 2016-04-13 Tu, X.,Wilmot, C.M. Crystal structures reveal metal-binding plasticity at the active site of PqqB To Be Published 0 0 0 0
5COR 27091995 X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER 2015-07-20 2016-04-13 Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA 2016 113 5000 5005
5COY 27091995 Crystal structure of CC chemokine 5 (CCL5) 2015-07-20 2016-04-13 Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA 2016 113 5000 5005
5DNF 27091995 Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin 2015-09-10 2016-04-13 Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA 2016 113 5000 5005
4Z7R The 1.98-angstrom crystal structure of Zn(2+)-bound PqqB from Methylobacterium extorquens 2015-04-07 2016-04-20 Tu, X.,Wimot, C.M. Crystal structures reveal metal-binding plasticity at active site of PqqB To Be Published 0 0 0 0
5D65 27091995 X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX 2015-08-11 2016-04-20 Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J. Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA 2016 113 5000 5005
5JBR Crystal structure of uncharacterized protein Bcav_2135 from Beutenbergia cavernae 2016-04-13 2016-04-20 Chang, C.,Cuff, M.,Hatzos-Skintges, C.,Jedrzejczak, R.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of uncharacterized protein Bcav_2135 from Beutenbergia cavernae To Be Published 0 0 0 0
5IJE 28567254 Crystal structure of Equine Serum Albumin in the presence of 30 mM zinc at pH 7.4 2016-03-01 2016-04-27 Handing, K.B.,Shabalin, I.G.,Kassaar, O.,Khazaipoul, S.,Blindauer, C.A.,Stewart, A.J.,Chruszcz, M.,Minor, W. Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins. Chem Sci 2016 7 6635 6648
5J7M Crystal structure of Cupin 2 conserved barrel domain protein from Kribbella flavida DSM 17836 2016-04-06 2016-04-27 Chang, C.,Cuff, M.,Chhor, G.,Endres, M.,Joachimiak, A. Crystal structure of Cupin 2 conserved barrel domain protein from Kribbella flavida DSM 17836 To Be Published 0 0 0 0
5JPD Metal ABC transporter from Listeria monocytogenes with cadmium 2016-05-03 2016-05-11 Osipiuk, J.,Zhou, M.,Grimshaw, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Metal ABC transporter from Listeria monocytogenes with cadmium to be published 0 0 0 0
5HYR 26928945 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-SP2 and Estradiol 2016-02-01 2016-05-25 Speltz, T.E.,Fanning, S.W.,Mayne, C.G.,Fowler, C.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew.Chem.Int.Ed.Engl. 2016 55 4252 4255
5J63 27171345 Crystal Structure of the N-terminal N-formyltransferase Domain (residues 1-306) of Escherichia coli Arna in Complex with UDP-Ara4N and Folinic Acid 2016-04-04 2016-05-25 Genthe, N.A.,Thoden, J.B.,Holden, H.M. Structure of the Escherichia coli ArnA N-formyltransferase domain in complex with N(5) -formyltetrahydrofolate and UDP-Ara4N. Protein Sci. 2016 25 1555 1562
5EVE 27231348 Crystal structure of Amb a 8 in complex with poly-Pro10 2015-11-19 2016-06-08 Offermann, L.R.,Schlachter, C.R.,Perdue, M.L.,Majorek, K.A.,He, J.Z.,Booth, W.T.,Garrett, J.,Kowal, K.,Chruszcz, M. Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2. J.Biol.Chem. 2016 291 15447 15459
5JMU The crystal structure of the catalytic domain of peptidoglycan N-acetylglucosamine deacetylase from Eubacterium rectale ATCC 33656 2016-04-29 2016-06-29 Tan, K.,Gu, M.,Clancy, S.,Joachimiak, A. The crystal structure of the catalytic domain of peptidoglycan N-acetylglucosamine deacetylase from Eubacterium rectale ATCC 33656 (CASP target) To Be Published 0 0 0 0
5KF9 27348258 X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum in complex with N-acetylglucosamine 2016-06-12 2016-07-06 Dopkins, B.J.,Tipton, P.A.,Thoden, J.B.,Holden, H.M. Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase. Biochemistry 2016 55 4495 4508
5DX3 26928945 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P3 and Estradiol 2015-09-23 2016-07-20 Speltz, T.E.,Fanning, S.W.,Mayne, C.G.,Fowler, C.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew.Chem.Int.Ed.Engl. 2016 55 4252 4255
5DXB 26928945 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P1 and Estradiol 2015-09-23 2016-07-27 Speltz, T.E.,Fanning, S.W.,Mayne, C.G.,Fowler, C.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew. Chem. Int. Ed. Engl. 2016 55 4252 4255
5DXG 26928945 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P5 2015-09-23 2016-07-27 Speltz, T.E.,Fanning, S.W.,Mayne, C.G.,Fowler, C.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew. Chem. Int. Ed. Engl. 2016 55 4252 4255
5DXE 26928945 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P4 and Estradiol 2015-09-23 2016-08-03 Speltz, T.E.,Fanning, S.W.,Mayne, C.G.,Fowler, C.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angew.Chem.Int.Ed.Engl. 2016 55 4252 4255
5D1V Crystal Structure and Thermal Stability of Hemoglobin from Thermophilic Phototrophic Bacterium Chloroflexus aurantiacus 2015-08-04 2016-08-10 Fromme, R.,Holl, M.,Tang, J.K. Crystal Structure and Thermal Stability of Hemoglobin from Thermophilic Phototrophic Bacterium Chloroflexus aurantiacus To Be Published 0 0 0 0
5L1A Crystal structure of uncharacterized protein LPG2271 from Legionella pneumophila 2016-07-28 2016-08-10 Chang, C.,Xu, X.,Cui, H.,Yim, V.,Savchenko, A.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of uncharacterized protein LPG2271 from Legionella pneumophila To Be Published 0 0 0 0
5T2X Crystal structure of Uncharacterised protein lpg1670 2016-08-24 2016-09-28 Chang, C.,Xu, X.,Cui, H.,SAVCHENKO, A.,JOACHIMIAK, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of Uncharacterised protein lpg1670 To Be Published 0 0 0 0
5KQG 27676368 Co-crystal structure of LMW-PTP in complex with 2-(benzothiazol-2-ylamino)-2-oxo-1-phenylethanesulfonic acid 2016-07-06 2016-10-12 He, R.,Wang, J.,Yu, Z.H.,Zhang, R.Y.,Liu, S.,Wu, L.,Zhang, Z.Y. Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem. 2016 0 0 0
5KQM 27676368 Co-crystal structure of LMW-PTP in complex with MES 2016-07-06 2016-10-12 He, R.,Wang, J.,Yu, Z.H.,Zhang, R.Y.,Liu, S.,Wu, L.,Zhang, Z.Y. Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem. 2016 0 0 0
5KQP 27676368 Crystal structure of Apo-form LMW-PTP 2016-07-06 2016-10-12 He, R.,Wang, J.,Yu, Z.H.,Zhang, R.Y.,Liu, S.,Wu, L.,Zhang, Z.Y. Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem. 2016 0 0 0
5TGN Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus 2016-09-28 2016-10-26 Michalska, K.,Li, H.,Clancy, S.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus To Be Published 0 0 0 0
5E95 27820802 Crystal Structure of Mb(NS1)/H-Ras Complex 2015-10-14 2016-11-02 Spencer-Smith, R.,Koide, A.,Zhou, Y.,Eguchi, R.R.,Sha, F.,Gajwani, P.,Santana, D.,Gupta, A.,Jacobs, M.,Herrero-Garcia, E.,Cobbert, J.,Lavoie, H.,Smith, M.,Rajakulendran, T.,Dowdell, E.,Okur, M.N.,Dementieva, I.,Sicheri, F.,Therrien, M.,Hancock, J.F.,Ikura, M.,Koide, S.,O'Bryan, J.P. Inhibition of RAS function through targeting an allosteric regulatory site. Nat. Chem. Biol. 2017 13 62 68
5TME 27715009 Crystal structure of Os79 from O. sativa in complex with UDP. 2016-10-12 2016-11-02 Wetterhorn, K.M.,Newmister, S.A.,Caniza, R.K.,Busman, M.,McCormick, S.P.,Berthiller, F.,Adam, G.,Rayment, I. Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol. Biochemistry 2016 55 6175 6186
5G18 27795378 Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate 2016-03-23 2016-11-09 Vandavasi, V.G.,Langan, P.S.,Weiss, K.L.,Parks, J.M.,Cooper, J.B.,Ginell, S.L.,Coates, L. Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate. Antimicrob. Agents Chemother. 2017 61 0 0
5TK2 Crystal Structure of Uncharacterized Cupredoxin-like domain protein from Bacillus anthracis 2016-10-06 2016-11-16 Kim, Y.,Maltseva, N.,Shatsman, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Uncharacterized Cupredoxin-like domain protein from Bacillus anthracis To Be Published 0 0 0 0
5BX1 Crystal Structure of PRL-1 complex with compound analogy 3 2015-06-08 2016-12-21 Liu, S.,Bai, Y.,Zhang, Z. Crystal Structure of PRL-1 complex with compound analogy 3 To Be Published 0 0 0 0
5JW6 28045392 Cystal structure of aspartate semialdehyde dehydrogenase from Aspergillus fumigatus 2016-05-11 2017-01-11 Dahal, G.P.,Viola, R.E. Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus. Acta Crystallogr F Struct Biol 2017 73 36 44
5T83 28017522 Structure of a guanidine-I riboswitch from S. acidophilus 2016-09-06 2017-01-11 Reiss, C.W.,Xiong, Y.,Strobel, S.A. Structural Basis for Ligand Binding to the Guanidine-I Riboswitch. Structure 2017 25 195 202
5UFH The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 2017-01-04 2017-01-18 Tan, K.,Li, H.,Endres, M.,Joachimiak, A. The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 To Be Published 0 0 0 0
5HUP 28618168 Crystal Structure of NadC from Streptococcus pyogenes 2016-01-27 2017-01-25 Booth, W.T.,Morris, T.L.,Mysona, D.P.,Shah, M.J.,Taylor, L.K.,Karlin, T.W.,Clary, K.,Majorek, K.A.,Offermann, L.R.,Chruszcz, M. Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD(+) synthetase. FEBS J. 2017 284 2425 2441
5UHJ The crystal structure of a natural product biosynthetic enzyme from Streptomyces sp. CB03234 2017-01-11 2017-01-25 Tan, K.,Li, H.,Endres, M.,Phillips Jr., G.N.,Joachimiak, A. The crystal structure of a natural product biosynthetic enzyme from Streptomyces sp. CB03234 To Be Published 0 0 0 0
5UJW Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4 2017-01-19 2017-02-08 Chang, C.,Maltseva, N.,Kim, Y.,Shatsman, S.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4 To Be Published 0 0 0 0
5JSP 27755868 New Mechanistic Insight from Substrate and Product Bound Structures of the Metal-dependent Dimethylsulfoniopropionate Lyase DddQ 2016-05-09 2017-02-22 Brummett, A.E.,Dey, M. New Mechanistic Insight from Substrate- and Product-Bound Structures of the Metal-Dependent Dimethylsulfoniopropionate Lyase DddQ. Biochemistry 2016 55 6162 6174
5JSR 27755868 New Mechanistic Insight from Substrate and Product Bound Structures of the Metal-dependent Dimethylsulfoniopropionate Lyase DddQ 2016-05-09 2017-02-22 Brummett, A.E.,Dey, M. New Mechanistic Insight from Substrate- and Product-Bound Structures of the Metal-Dependent Dimethylsulfoniopropionate Lyase DddQ. Biochemistry 2016 55 6162 6174
5UJP The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 2017-01-18 2017-02-22 Tan, K.,Li, H.,Endres, M.,Phillips Jr., G.N.,Joachimiak, A. The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 To Be Published 0 0 0 0
5UPT 29867143 Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP468 ligand 2017-02-03 2017-02-22 Wang, N.,Rudolf, J.D.,Dong, L.B.,Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Chang, C.Y.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B. Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol. 2018 14 730 737
5UTT 31427528 SrtA sortase from Actinomyces oris 2017-02-15 2017-03-01 Chang, C.,Wu, C.,Osipiuk, J.,Siegel, S.D.,Zhu, S.,Liu, X.,Joachimiak, A.,Clubb, R.T.,Das, A.,Ton-That, H. Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes. Proc.Natl.Acad.Sci.USA 2019 116 18041 18049
5IBY Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-2) in complex with lipoic acid 2016-02-22 2017-03-15 Hughes, S.J.,Song, J.H.,Antoshchenko, T.,Park, H.W. Crystal structure of Enterococcus faecalis lipoate protein ligase A (lplA-2) in complex with lipoic acid TO BE PUBLISHED 0 0 0 0
5ICH Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-2) in complex with 8BO-AMP 2016-02-23 2017-03-15 Hughes, S.J.,Song, J.H.,Antoshchenko, T.,Park, H.W. Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-2) in complex with 8BO-AMP to be published 0 0 0 0
5UWY The crystal structure of thioredoxin reductase from Streptococcus pyogenes MGAS5005 2017-02-21 2017-03-15 Tan, K.,Zhou, M.,Anderson, W.F.,Joachimiak, A. The crystal structure of thioredoxin reductase from Streptococcus pyogenes MGAS5005 To Be Published 0 0 0 0
5UZE Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182 2017-02-26 2017-03-22 Maltseva, N.,Kim, Y.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.R.,Hedstrom, L.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182 To Be Published 0 0 0 0
5UZS Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200 2017-02-27 2017-03-22 Maltseva, N.,Kim, Y.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.R.,Hedstrom, L.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200 To Be Published 0 0 0 0
5V0P Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA 2017-02-28 2017-03-22 Hou, J.,Zheng, H.,Cooper, D.R.,Chruszcz, M.,Chordia, M.D.,Grabowski, M.,Minor, W. Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA To Be Published 0 0 0 0
5MTJ 28347651 Yes1-SH2 in complex with monobody Mb(Yes_1) 2017-01-09 2017-04-05 Kukenshoner, T.,Schmit, N.E.,Bouda, E.,Sha, F.,Pojer, F.,Koide, A.,Seeliger, M.,Koide, S.,Hantschel, O. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J. Mol. Biol. 2017 429 1364 1380
5MTJ 28347651 Yes1-SH2 in complex with monobody Mb(Yes_1) 2017-01-09 2017-04-05 Kukenshoner, T.,Schmit, N.E.,Bouda, E.,Sha, F.,Pojer, F.,Koide, A.,Seeliger, M.,Koide, S.,Hantschel, O. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J. Mol. Biol. 2017 429 1364 1380
5VPH 22210776 CRYSTAL STRUCTURE OF DER P 1 COMPLEXED WITH FAB 4C1 2017-05-05 2017-05-24 Chruszcz, M.,Pomes, A.,Glesner, J.,Vailes, L.D.,Osinski, T.,Porebski, P.J.,Majorek, K.A.,Heymann, P.W.,Platts-Mills, T.A.,Minor, W.,Chapman, M.D. Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens. J.Biol.Chem. 2012 287 7388 0
5VSV Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225 2017-05-12 2017-05-24 Maltseva, N.,Kim, Y.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.R.,Hedstrom, L.,Joachimiak, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225 To Be Published 0 0 0 0
5SUL 27935293 Inhibited state structure of yGsy2p 2016-08-03 2017-06-14 Mahalingan, K.K.,Baskaran, S.,DePaoli-Roach, A.A.,Roach, P.J.,Hurley, T.D. Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation. Biochemistry 2017 56 179 188
5VUG Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase Domain of Uncharacterized Protein Rv2277c from Mycobacterium tuberculosis 2017-05-19 2017-06-14 Kim, Y.,Li, H.,Endres, M.,Joachimiak, A. Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase Domain of Uncharacterized Protein Rv2277c from Mycobacterium tuberculosis To Be Published 0 0 0 0
5VYM Crystal structure of beta-galactosidase from Bifidobacterium adolescentis 2017-05-25 2017-08-02 Chang, C.,Cuff, M.,Tesar, C.,Endres, M.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of beta-galactosidase from Bifidobacterium adolescentis To Be Published 0 0 0 0
5V8K 28751471 Homodimeric reaction center of H. modesticaldum 2017-03-22 2017-09-06 Gisriel, C.,Sarrou, I.,Ferlez, B.,Golbeck, J.H.,Redding, K.E.,Fromme, R. Structure of a symmetric photosynthetic reaction center-photosystem. Science 2017 357 1021 1025
5VIM 28876240 Crystal structure of the Zika virus NS5 methyltransferase. 2017-04-17 2017-09-06 Bukrejewska, M.,Derewenda, U.,Radwanska, M.,Engel, D.A.,Derewenda, Z.S. Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain. Acta Crystallogr D Struct Biol 2017 73 767 774
5W9D 29739819 Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen 2017-06-23 2017-10-11 Maximov, P.Y.,Abderrahman, B.,Fanning, S.W.,Sengupta, S.,Fan, P.,Curpan, R.F.,Rincon, D.M.Q.,Greenland, J.A.,Rajan, S.S.,Greene, G.L.,Jordan, V.C. Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol. 2018 94 812 822
5V2M 29025876 Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis 2017-03-05 2017-10-18 Chen, C.L.,Mermoud, J.C.,Paul, L.N.,Steussy, C.N.,Stauffacher, C.V. Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis. J. Biol. Chem. 2017 292 21340 21351
5VXH 29025976 Crystal structure of Xanthomonas campestris OleA E117D 2017-05-23 2017-10-25 Jensen, M.R.,Goblirsch, B.R.,Christenson, J.K.,Esler, M.A.,Mohamed, F.A.,Wackett, L.P.,Wilmot, C.M. OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J. 2017 474 3871 3886
5VXI 29025976 Crystal structure of Xanthomonas campestris OleA E117D bound with Cerulenin 2017-05-23 2017-10-25 Jensen, M.R.,Goblirsch, B.R.,Christenson, J.K.,Esler, M.A.,Mohamed, F.A.,Wackett, L.P.,Wilmot, C.M. OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J. 2017 474 3871 3886
5BJW 29053280 X-ray structure of the PglF 4,6-dehydratase from campylobacter jejuni, T595S variant, in complex with UDP 2017-09-12 2017-11-08 Riegert, A.S.,Thoden, J.B.,Schoenhofen, I.C.,Watson, D.C.,Young, N.M.,Tipton, P.A.,Holden, H.M. Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily. Biochemistry 2017 56 6030 6040
5BJX 29053280 X-ray structure of the PglF 4,6-dehydratase from campylobacter jejuni, variant T395V, in complex with UDP 2017-09-12 2017-11-08 Riegert, A.S.,Thoden, J.B.,Schoenhofen, I.C.,Watson, D.C.,Young, N.M.,Tipton, P.A.,Holden, H.M. Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily. Biochemistry 2017 56 6030 6040
5BJY 29053280 x-ray structure of the PglF 4,5-dehydratase from campylobacter jejuni, variant M405Y, in complex with UDP 2017-09-12 2017-11-08 Riegert, A.S.,Thoden, J.B.,Schoenhofen, I.C.,Watson, D.C.,Young, N.M.,Tipton, P.A.,Holden, H.M. Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily. Biochemistry 2017 56 6030 6040
5WI4 29089450 CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2 2017-07-18 2017-11-15 Sandi, M.J.,Marshall, C.B.,Balan, M.,Coyaud, E.,Zhou, M.,Monson, D.M.,Ishiyama, N.,Chandrakumar, A.A.,La Rose, J.,Couzens, A.L.,Gingras, A.C.,Raught, B.,Xu, W.,Ikura, M.,Morrison, D.K.,Rottapel, R. MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Sci Signal 2017 10 0 0
6BK1 29140092 Crystal structure of Os79 T291V from O. sativa in complex with UDP. 2017-11-07 2017-11-29 Wetterhorn, K.M.,Gabardi, K.,Michlmayr, H.,Malachova, A.,Busman, M.,McCormick, S.P.,Berthiller, F.,Adam, G.,Rayment, I. Determinants and Expansion of Specificity in a Trichothecene UDP-Glucosyltransferase from Oryza sativa. Biochemistry 2017 56 6585 6596
6BK3 29140092 Crystal structure of Os79 from O. sativa in complex with UDP and deoxynivalenol-3-glucoside (glucose moitey not resolved) 2017-11-07 2017-11-29 Wetterhorn, K.M.,Gabardi, K.,Michlmayr, H.,Malachova, A.,Busman, M.,McCormick, S.P.,Berthiller, F.,Adam, G.,Rayment, I. Determinants and Expansion of Specificity in a Trichothecene UDP-Glucosyltransferase from Oryza sativa. Biochemistry 2017 56 6585 6596
6APJ 29251719 Crystal Structure of human ST6GALNAC2 2017-08-17 2017-12-20 Moremen, K.W.,Ramiah, A.,Stuart, M.,Steel, J.,Meng, L.,Forouhar, F.,Moniz, H.A.,Gahlay, G.,Gao, Z.,Chapla, D.,Wang, S.,Yang, J.Y.,Prabhakar, P.K.,Johnson, R.,Rosa, M.D.,Geisler, C.,Nairn, A.V.,Seetharaman, J.,Wu, S.C.,Tong, L.,Gilbert, H.J.,LaBaer, J.,Jarvis, D.L. Expression system for structural and functional studies of human glycosylation enzymes. Nat. Chem. Biol. 2018 14 156 162
5UFW 29915250 Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1154 2017-01-06 2018-01-10 Fanning, S.W.,Hodges-Gallagher, L.,Myles, D.C.,Sun, R.,Fowler, C.E.,Plant, I.N.,Green, B.D.,Harmon, C.L.,Greene, G.L.,Kushner, P.J. Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun 2018 9 2368 2368
5UFX 29915250 Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1074 2017-01-06 2018-01-10 Fanning, S.W.,Hodges-Gallagher, L.,Myles, D.C.,Sun, R.,Fowler, C.E.,Plant, I.N.,Green, B.D.,Harmon, C.L.,Greene, G.L.,Kushner, P.J. Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun 2018 9 2368 2368
5WHS 29305053 Crystal structure of the catalase-peroxidase from Neurospora crassa at 2.6 A 2017-07-18 2018-01-17 Vega-Garcia, V.,Diaz-Vilchis, A.,Saucedo-Vazquez, J.P.,Solano-Peralta, A.,Rudino-Pinera, E.,Hansberg, W. Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase. Arch. Biochem. Biophys. 2018 640 17 26
6BWL 29266550 X-ray structure of Pal from Bacillus thuringiensis 2017-12-15 2018-01-17 Delvaux, N.A.,Thoden, J.B.,Holden, H.M. Molecular architectures of Pen and Pal: Key enzymes required for CMP-pseudaminic acid biosynthesis in Bacillus thuringiensis. Protein Sci. 2018 27 738 749
6C5C 35512834 Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH 2018-01-16 2018-01-24 Stogios, P.J.,Liston, S.D.,Semper, C.,Quade, B.,Michalska, K.,Evdokimova, E.,Ram, S.,Otwinowski, Z.,Borek, D.,Cowen, L.E.,Savchenko, A. Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance 2022 5 0 0
6C42 29915250 Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1156 2018-01-11 2018-02-14 Fanning, S.W.,Hodges-Gallagher, L.,Myles, D.C.,Sun, R.,Fowler, C.E.,Plant, I.N.,Green, B.D.,Harmon, C.L.,Greene, G.L.,Kushner, P.J. Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun 2018 9 2368 2368
6B5E 29076563 Mycobacterium tuberculosis RmlA in complex with dTDP-glucose 2017-09-29 2018-02-21 Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M. The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes. Protein Sci. 2018 27 441 450
6B5K 29076563 Mycobacterium tuberculosis RmlA in complex with Mg/dTTP 2017-09-29 2018-02-21 Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M. The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes. Protein Sci. 2018 27 441 450
6BL5 29779790 Head decoration protein from the hyperthermophilic phage P74-26 2017-11-09 2018-02-21 Stone, N.P.,Hilbert, B.J.,Hidalgo, D.,Halloran, K.T.,Lee, J.,Sontheimer, E.J.,Kelch, B.A. A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein. Structure 2018 26 936 0
6CBL 29516565 x-ray structure of NeoB from Streptomyces fradiae in complex with neamine as an external aldimine 2018-02-03 2018-02-21 Dow, G.T.,Thoden, J.B.,Holden, H.M. The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. Protein Sci. 2018 27 945 956
6CBO 29516565 X-ray structure of GenB1 from micromonospora echinospora in complex with neamine and PLP (as the external aldimine) 2018-02-03 2018-02-21 Dow, G.T.,Thoden, J.B.,Holden, H.M. The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. Protein Sci. 2018 27 945 956
6B2R 29430657 Crystal structure of Xanthomonas campestris OleA H285A 2017-09-20 2018-02-28 Jensen, M.R.,Goblirsch, B.R.,Esler, M.A.,Christenson, J.K.,Mohamed, F.A.,Wackett, L.P.,Wilmot, C.M. The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. FEBS Lett. 2018 592 987 998
6CBZ 29739819 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Estradiol and GRIP Peptide 2018-02-05 2018-02-28 Maximov, P.Y.,Abderrahman, B.,Fanning, S.W.,Sengupta, S.,Fan, P.,Curpan, R.F.,Rincon, D.M.Q.,Greenland, J.A.,Rajan, S.S.,Greene, G.L.,Jordan, V.C. Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol. 2018 94 812 822
5VBS 28752992 Structural basis for a six letter alphabet including GATCKX 2017-03-30 2018-03-07 Singh, I.,Kim, M.J.,Molt, R.W.,Hoshika, S.,Benner, S.A.,Georgiadis, M.M. Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K). ACS Synth Biol 2017 6 2118 2129
6CBK 29516565 X-ray structure of NeoB from Streptomyces fradiae in complex with PMP 2018-02-03 2018-03-07 Dow, G.T.,Thoden, J.B.,Holden, H.M. The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin. Protein Sci. 2018 27 945 956
6APC 29396163 Crystal Structure of Infant Antibody ADI-19425 2017-08-17 2018-03-21 Goodwin, E.,Gilman, M.S.A.,Wrapp, D.,Chen, M.,Ngwuta, J.O.,Moin, S.M.,Bai, P.,Sivasubramanian, A.,Connor, R.I.,Wright, P.F.,Graham, B.S.,McLellan, J.S.,Walker, L.M. Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity 2018 48 339 0
6D28 12970348 Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA 2018-04-13 2018-05-16 Soldano, K.L.,Jivan, A.,Nicchitta, C.V.,Gewirth, D.T. Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation. J. Biol. Chem. 2003 278 48330 48338
6DFP 35435721 Crystal Structure of a Tripartite Toxin Component VCA0883 from Vibrio cholerae 2018-05-15 2018-05-23 Herrera, A.,Kim, Y.,Chen, J.,Jedrzejczak, R.,Shukla, S.,Maltseva, N.,Joachimiak, G.,Welk, L.,Wiersum, G.,Jaroszewski, L.,Godzik, A.,Joachimiak, A.,Satchell, K.J.F. A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins. J.Bacteriol. 2022 204 0 0
6DFU Tryptophan--tRNA ligase from Haemophilus influenzae. 2018-05-15 2018-05-23 Osipiuk, J.,Maltseva, N.,Mulligan, R.,Grimshaw, S.,Satchell, K.J.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Tryptophan--tRNA ligase from Haemophilus influenzae. to be published 0 0 0 0
6D60 29784877 Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142P from Cupriavidus metallidurans 2018-04-19 2018-06-06 Yang, Y.,Liu, F.,Liu, A. Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem. 2018 293 10415 10424
6D61 29784877 Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142P from Cupriavidus metallidurans in complex with 4-Cl-3-HAA 2018-04-19 2018-06-06 Yang, Y.,Liu, F.,Liu, A. Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem. 2018 293 10415 10424
6D62 29784877 Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142P from Cupriavidus metallidurans in complex with 3-HAA 2018-04-19 2018-06-06 Yang, Y.,Liu, F.,Liu, A. Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem. 2018 293 10415 10424
5W2B 29968677 Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment 2017-06-06 2018-06-13 Radwanska, M.J.,Jaskolowski, M.,Davydova, E.,Derewenda, U.,Miyake, T.,Engel, D.A.,Kossiakoff, A.A.,Derewenda, Z.S. The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol 2018 74 681 689
5W9C 29739819 Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen 2017-06-23 2018-06-13 Maximov, P.Y.,Abderrahman, B.,Fanning, S.W.,Sengupta, S.,Fan, P.,Curpan, R.F.,Rincon, D.M.Q.,Greenland, J.A.,Rajan, S.S.,Greene, G.L.,Jordan, V.C. Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol. 2018 94 812 822
5WGD 29725689 Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-LP1 2017-07-14 2018-06-13 Speltz, T.E.,Mayne, C.G.,Fanning, S.W.,Siddiqui, Z.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. A ""cross-stitched"" peptide with improved helicity and proteolytic stability. Org. Biomol. Chem. 2018 16 3702 3706
5WGQ 29725689 Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-BCP1 2017-07-14 2018-06-13 Speltz, T.E.,Mayne, C.G.,Fanning, S.W.,Siddiqui, Z.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. A ""cross-stitched"" peptide with improved helicity and proteolytic stability. Org. Biomol. Chem. 2018 16 3702 3706
5VZ1 Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) 2017-05-26 2018-06-27 Radwanska, M.J.,Derewenda, U.,Kossiakoff, A.,Derewenda, Z.S. Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) To Be Published 0 0 0 0
6BPS 29942080 Crystal structure of cysteine-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase 2017-11-26 2018-07-04 Li, J.,Griffith, W.P.,Davis, I.,Shin, I.,Wang, J.,Li, F.,Wang, Y.,Wherritt, D.J.,Liu, A. Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol. 2018 14 853 860
6BPT 29942080 Crystal structure of ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase 2017-11-26 2018-07-04 Li, J.,Griffith, W.P.,Davis, I.,Shin, I.,Wang, J.,Li, F.,Wang, Y.,Wherritt, D.J.,Liu, A. Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol. 2018 14 853 860
6HCD 23745136 Structure of universal stress protein from Archaeoglobus fulgidus 2018-08-14 2018-08-29 Tkaczuk, K.L.,A Shumilin, I.,Chruszcz, M.,Evdokimova, E.,Savchenko, A.,Minor, W. Structural and functional insight into the universal stress protein family. Evol Appl 2013 6 434 449
6AUB CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2815 2017-08-31 2018-09-12 Ortwine, D. To Be Determined TO BE PUBLISHED 0 0 0 0
6AWR Structure of PR 10 Allergen Ara h 8.01 in complex with ANS 2017-09-06 2018-09-12 Offermann, L.R.,Yarbrough, J.,McBride, J.,Hurlburt, B.K.,Maleki, S.J.,Pote, S.S.,Chruszcz, M. Structure of PR-10 Allergen Ara h 8.01. To Be Published 0 0 0 0
6AWS Structure of PR 10 Allergen Ara h 8.01 in complex with quercetin 2017-09-06 2018-09-12 Offermann, L.R.,Yarbrough, J.,McBride, J.,Hurlburt, B.K.,Maleki, S.J.,Pote, S.S.,Chruszcz, M. Structure of PR-10 Allergen Ara h 8.01. To Be Published 0 0 0 0
6AWT Structure of PR 10 Allergen in complex with epicatechin 2017-09-06 2018-09-12 Offermann, L.R.,Yarbrough, J.,McBride, J.,Hurlburt, B.K.,Maleki, S.J.,Pote, S.S.,Chruszcz, M. Structure of PR-10 Allergen Ara h 8.01. To Be Published 0 0 0 0
6MGG Succinyl-CoA synthase from Francisella tularensis, phosphorylated, in complex with CoA 2018-09-13 2018-09-26 Osipiuk, J.,Maltseva, N.,Jedrzejczak, R.,Satchell, K.J.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Succinyl-CoA synthase from Francisella tularensis to be published 0 0 0 0
6DED 30322896 Crystal structure of the C-terminal ARM domain of Homo sapiens SPIN90 (SH3-protein interacting with Nck), residues 351-722 2018-05-11 2018-10-24 Luan, Q.,Liu, S.L.,Helgeson, L.A.,Nolen, B.J. Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex. EMBO J. 2018 37 0 0
6MN1 Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA 2018-10-01 2018-10-24 Stogios, P.J. Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA To Be Published 0 0 0 0
6MN2 Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with sisomicin-CoA 2018-10-01 2018-10-24 Stogios, P.J. Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with sisomicin-CoA To Be Published 0 0 0 0
6MN4 35338238 Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with apramycin 2018-10-01 2018-10-24 Stogios, P.J.,Bordeleau, E.,Xu, Z.,Skarina, T.,Evdokimova, E.,Chou, S.,Diorio-Toth, L.,D'Souza, A.W.,Patel, S.,Dantas, G.,Wright, G.D.,Savchenko, A. Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol 2022 5 263 263
6MIB 30367047 Crystal structure of the ILK ATP-binding deficient mutant (L207W)/alpha-parvin core complex 2018-09-19 2018-11-07 Vaynberg, J.,Fukuda, K.,Lu, F.,Bialkowska, K.,Chen, Y.,Plow, E.F.,Qin, J. Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion. Nat Commun 2018 9 4465 4465
5V85 The crystal structure of the protein of DegV family COG1307 from Ruminococcus gnavus ATCC 29149 (alternative refinement of PDB 3JR7 with Vaccenic acid) 2017-03-21 2018-11-21 Cuypers, M.G.,Ericson, M.,Subramanian, C.,Broussard, T.C.,Miller, D.J.,White, S.W.,Rock, C.O. The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution J.Biol.Chem. 2018 0 0 0
6N9K Beta-lactamase from Escherichia coli str. Sakai 2018-12-03 2018-12-12 Osipiuk, J.,Wu, R.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Beta-lactamase from Escherichia coli str. Sakai to be published 0 0 0 0
6B6Z Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) 2017-10-03 2018-12-19 Radwanska, M.J.,Derewenda, U.,Kossiakoff, A.A.,Derewenda, Z.S. Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) To Be Published 0 0 0 0
6N1N Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 2018-11-09 2018-12-19 Michalska, K.,Tesar, C.,Endres, M.,Joachimiak, A.,Satchell, K.J.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 To Be Published 0 0 0 0
6NHS Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc 2018-12-23 2019-01-16 Kim, Y.,Tesar, C.,Endres, M.,Babnigg, G.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc To Be Published 0 0 0 0
6NHU Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum 2018-12-23 2019-01-16 Kim, Y.,Welk, L.,Endres, M.,Babnigg, G.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum To Be Published 0 0 0 0
6NI0 Crystal Structure of the Beta Lactamase Class D YbxI from Burkholderia thailandensis 2018-12-25 2019-01-16 Kim, Y.,Wu, R.,Endres, R.,Babnigg, G.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Beta Lactamase Class D YbxI from Burkholderia thailandensis To Be Published 0 0 0 0
6MHM 30525581 Crystal structure of human acid ceramidase in covalent complex with carmofur 2018-09-18 2019-01-23 Dementiev, A.,Joachimiak, A.,Nguyen, H.,Gorelik, A.,Illes, K.,Shabani, S.,Gelsomino, M.,Ahn, E.E.,Nagar, B.,Doan, N. Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur. J. Med. Chem. 2019 62 987 992
6NLW The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 2019-01-09 2019-01-23 Tan, K.,Tesar, C.,Endres, M.,Joachimiak, A. The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 To Be Published 0 0 0 0
6NPO Crystal structure of oligopeptide ABC transporter from Bacillus anthracis str. Ames (substrate-binding domain) 2019-01-18 2019-02-06 Michalska, K.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal structure of oligopeptide ABC transporter from Bacillus anthracis str. Ames (substrate-binding domain) To Be Published 0 0 0 0
6NYC 20154707 Munc13-1 C2B-domain, calcium free 2019-02-11 2019-02-20 Shin, O.H.,Lu, J.,Rhee, J.S.,Tomchick, D.R.,Pang, Z.P.,Wojcik, S.M.,Camacho-Perez, M.,Brose, N.,Machius, M.,Rizo, J.,Rosenmund, C.,Sudhof, T.C. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol. 2010 17 280 288
6NYT 20154707 Munc13-1 C2B-domain, calcium bound 2019-02-12 2019-02-20 Shin, O.H.,Lu, J.,Rhee, J.S.,Tomchick, D.R.,Pang, Z.P.,Wojcik, S.M.,Camacho-Perez, M.,Brose, N.,Machius, M.,Rizo, J.,Rosenmund, C.,Sudhof, T.C. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol. 2010 17 280 288
6O6D N-terminal domain of translation initiation factor IF-3 from Helicobacter pylori 2019-03-06 2019-03-13 Osipiuk, J.,Tesar, C.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) N-terminal domain of translation initiation factor IF-3 from Helicobacter pylori to be published 0 0 0 0
6CZN Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide 2018-04-09 2019-03-20 Fanning, S.W. Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide To Be Published 0 0 0 0
6CN9 15242606 Crystal structure of the Kinase domain of WNK1 2018-03-07 2019-03-27 Min, X.,Lee, B.H.,Cobb, M.H.,Goldsmith, E.J. Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension. Structure 2004 12 1303 1311
6BPR 30946568 Crystal structure of cysteine, nitric oxide-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase 2017-11-26 2019-04-17 Li, J.,Koto, T.,Davis, I.,Liu, A. Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry 2019 58 2218 2227
6D0F Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide 2018-04-10 2019-04-17 fanning, s.w. Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide To Be Published 0 0 0 0
6D1D 31483651 Crystal structure of NDM-1 complexed with compound 6 2018-04-11 2019-04-17 Pemberton, O.A.,Jaishankar, P.,Akhtar, A.,Adams, J.L.,Shaw, L.N.,Renslo, A.R.,Chen, Y. Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem. 2019 62 8480 8496
6D2S 31504787 Mycobacterium tuberculosis transcriptional regulator 2018-04-13 2019-04-17 Tang, S.,Hicks, N.D.,Cheng, Y.S.,Silva, A.,Fortune, S.M.,Sacchettini, J.C. Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor. Nucleic Acids Res. 2019 47 9934 9949
6EFJ 30942078 Crystal structure of NDM-1 with compound 9 2018-08-16 2019-04-17 Torelli, N.J.,Akhtar, A.,DeFrees, K.,Jaishankar, P.,Pemberton, O.A.,Zhang, X.,Johnson, C.,Renslo, A.R.,Chen, Y. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis. 2019 5 1013 1021
6M7I 30942078 Crystal structure of KPC-2 with compound 3 2018-08-20 2019-04-17 Torelli, N.J.,Akhtar, A.,DeFrees, K.,Jaishankar, P.,Pemberton, O.A.,Zhang, X.,Johnson, C.,Renslo, A.R.,Chen, Y. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis. 2019 5 1013 1021
6MD8 30942078 Crystal structure of CTX-M-14 with compound 3 2018-09-04 2019-04-17 Torelli, N.J.,Akhtar, A.,DeFrees, K.,Jaishankar, P.,Pemberton, O.A.,Zhang, X.,Johnson, C.,Renslo, A.R.,Chen, Y. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis. 2019 5 1013 1021
6MIA 30942078 Crystal structure of CTX-M-14 with compound 6 2018-09-19 2019-04-17 Torelli, N.J.,Akhtar, A.,DeFrees, K.,Jaishankar, P.,Pemberton, O.A.,Zhang, X.,Johnson, C.,Renslo, A.R.,Chen, Y. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis. 2019 5 1013 1021
6N42 30946568 Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition 2018-11-16 2019-04-17 Li, J.,Koto, T.,Davis, I.,Liu, A. Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry 2019 58 2218 2227
6OH7 30981884 Crystal structure of (E)-biformene synthase LrdC from Streptomyces sp. strain K155 in complex with Mg 2019-04-04 2019-04-17 Centeno-Leija, S.,Tapia-Cabrera, S.,Guzman-Trampe, S.,Esquivel, B.,Esturau-Escofet, N.,Tierrafria, V.H.,Rodriguez-Sanoja, R.,Zarate-Romero, A.,Stojanoff, V.,Rudino-Pinera, E.,Sanchez, S.,Serrano-Posada, H. The structure of (E)-biformene synthase provides insights into the biosynthesis of bacterial bicyclic labdane-related diterpenoids. J.Struct.Biol. 2019 207 29 39
6OFU 31322866 X-ray crystal structure of the YdjI aldolase from Escherichia coli K12 2019-04-01 2019-04-24 Huddleston, J.P.,Thoden, J.B.,Dopkins, B.J.,Narindoshvili, T.,Fose, B.J.,Holden, H.M.,Raushel, F.M. Structural and Functional Characterization of YdjI, an Aldolase of Unknown Specificity inEscherichia coliK12. Biochemistry 2019 58 3340 3353
6D8X PPAR gamma LBD complexed with the agonist GW1929 2018-04-27 2019-05-01 Chrisman, I.M.,Mou, T.C.,Sprang, S.R.,Hughes, T.S. PPAR gamma LBD complexed with the agonist GW1929 To Be Published 0 0 0 0
6D94 36469765 Crystal structure of PPAR gamma in complex with Mediator of RNA polymerase II transcription subunit 1 2018-04-27 2019-05-01 Nemetchek, M.D.,Chrisman, I.M.,Rayl, M.L.,Voss, A.H.,Hughes, T.S. A structural mechanism of nuclear receptor biased agonism. Proc.Natl.Acad.Sci.USA 2022 119 0 0
6OZ7 Putative oxidoreductase from Escherichia coli str. K-12 2019-05-15 2019-05-29 Osipiuk, J.,Skarina, T.,Mesa, N.,Endres, M.,Savchenko, A.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Putative oxidoreductase from Escherichia coli str. K-12 to be published 0 0 0 0
6OUX 31325159 Structure of SMUL_1544, a decarboxylase from Sulfurospirillum multivorans 2019-05-05 2019-06-05 Keller, S.,Wetterhorn, K.M.,Vecellio, A.,Seeger, M.,Rayment, I.,Schubert, T. Structural and functional analysis of an l-serine O-phosphate decarboxylase involved in norcobamide biosynthesis. Febs Lett. 2019 593 3040 3053
6O52 31176713 Room temperature structure of binary complex of native hAChE with BW284c51 2019-03-01 2019-06-19 Gerlits, O.,Ho, K.Y.,Cheng, X.,Blumenthal, D.,Taylor, P.,Kovalevsky, A.,Radic, Z. A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies. Chem.Biol.Interact. 2019 309 108698 108698
6NMG 31155309 Crystal Structure of Rat Ric-8A G alpha binding domain 2019-01-10 2019-06-26 Zeng, B.,Mou, T.C.,Doukov, T.I.,Steiner, A.,Yu, W.,Papasergi-Scott, M.,Tall, G.G.,Hagn, F.,Sprang, S.R. Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A. Structure 2019 27 1137 0
6ON3 31180203 A substrate bound structure of L-DOPA dioxygenase from Streptomyces sclerotialus 2019-04-19 2019-06-26 Wang, Y.,Shin, I.,Fu, Y.,Colabroy, K.L.,Liu, A. Crystal Structures of L-DOPA Dioxygenase fromStreptomyces sclerotialus. Biochemistry 2019 58 5339 5350
6MQG 31341022 Crystal structure of KRAS V14I-GDP demonstrating open switch 1 conformation - Form 1 2018-10-09 2019-07-31 Bera, A.K.,Lu, J.,Wales, T.E.,Gondi, S.,Gurbani, D.,Nelson, A.,Engen, J.R.,Westover, K.D. Structural basis of the atypical activation mechanism of KRASV14I. J.Biol.Chem. 2019 294 13964 13972
6P2N 31324716 Crystal structure of Paenibacillus graminis GH74 (PgGH74) 2019-05-21 2019-07-31 Arnal, G.,Stogios, P.J.,Asohan, J.,Attia, M.A.,Skarina, T.,Viborg, A.H.,Henrissat, B.,Savchenko, A.,Brumer, H. Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem. 2019 294 13233 13247
6EAL CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT D486N STABILIZED IN THE PREFUSION STATE 2018-08-03 2019-08-07 Battles, M.B.,McLellan, J.S. Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance To be published 0 0 0 0
6EAN CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT F488I STABILIZED IN THE PREFUSION STATE 2018-08-03 2019-08-07 Battles, M.B.,McLellan, J.S. Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance To be published 0 0 0 0
6MBX 31326654 CRYSTAL STRUCTURE OF MUSKMELON ALLERGEN CUC M 2 2018-08-30 2019-08-21 Kapingidza, A.B.,Pye, S.E.,Hyduke, N.,Dolamore, C.,Pote, S.,Schlachter, C.R.,Commins, S.P.,Kowal, K.,Chruszcz, M. Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins. Mol.Immunol. 2019 114 19 29
6U2Z Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed moxalactam and two copper ions 2019-08-21 2019-09-04 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed moxalactam and two copper ions To Be Published 0 0 0 0
6U0Z Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed penicillin G 2019-08-15 2019-09-11 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed penicillin G. To Be Published 0 0 0 0
6U13 Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed antibiotic moxalactam 2019-08-15 2019-09-11 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the hydrolyzed antibiotic moxalactam. To Be Published 0 0 0 0
6UAF Crystal Structure of the Metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the Complex with Hydrolyzed Imipnem 2019-09-10 2019-09-18 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the Complex with Hydrolyzed Imipnem To Be Published 0 0 0 0
6UAH Crystal Structure of the Metallo-beta-Lactamase L1 from Stenotrophomonas maltophilia in the Complex with Hydrolyzed Meropenem 2019-09-10 2019-09-18 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Metallo-beta-Lactamase L1 from Stenotrophomonas maltophilia in the Complex with Hydrolyzed Meropenem To Be Published 0 0 0 0
6NY7 31483651 Crystal Structure of NDM-1 D199N with Compound 16 2019-02-11 2019-09-25 Pemberton, O.A.,Jaishankar, P.,Akhtar, A.,Adams, J.L.,Shaw, L.N.,Renslo, A.R.,Chen, Y. Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem. 2019 62 8480 8496
6O3R 31483651 Crystal Structure of NDM-1 D199N with Compound 7 2019-02-27 2019-09-25 Pemberton, O.A.,Jaishankar, P.,Akhtar, A.,Adams, J.L.,Shaw, L.N.,Renslo, A.R.,Chen, Y. Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem. 2019 62 8480 8496
6PUA 31762145 The 2.0 A Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae 2019-07-18 2019-09-25 Alcala, A.,Ramirez, G.,Solis, A.,Kim, Y.,Tan, K.,Luna, O.,Nguyen, K.,Vazquez, D.,Ward, M.,Zhou, M.,Mulligan, R.,Maltseva, N.,Kuhn, M.L. Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species. Protein Sci. 2020 29 695 710
6PUB Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet 2019-07-18 2019-09-25 Kim, Y.,Maltseva, N.,Kuhn, M.,Stam, J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet To Be Published 0 0 0 0
6MM1 34278292 Structure of the cysteine-rich region from human EHMT2 2018-09-28 2019-10-02 Kerchner, K.M.,Mou, T.C.,Sun, Y.,Rusnac, D.V.,Sprang, S.R.,Briknarova, K. The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a). J Struct Biol X 2021 5 100050 100050
6U0A Human Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) with Glycerol 2019-08-14 2019-10-09 Tarver, C.L.,Yuan, Q.,Singhal, A.J.,Ramaker, R.,Cooper, S.,Pusey, M.L. Crystal Structures of Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) Reveal a Binding Pocket with Multiple Ligands To Be Published 0 0 0 0
6PIT 31523967 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with SRC2 Stapled Peptide 41A and Estradiol 2019-06-27 2019-10-16 Montgomery, J.E.,Donnelly, J.A.,Fanning, S.W.,Speltz, T.E.,Shangguan, X.,Coukos, J.S.,Greene, G.L.,Moellering, R.E. Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. J.Am.Chem.Soc. 2019 141 16374 16381
6UN1 31685462 Crystal structure of Pseudomonas aeruginosa PBP3 in complex with temocillin 2019-10-10 2019-10-30 Sacco, M.D.,Kroeck, K.G.,Kemp, M.T.,Zhang, X.,Andrews, L.D.,Chen, Y. Influence of the alpha-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 beta-Lactamase. Antimicrob.Agents Chemother. 2019 64 0 0
6UEC 31664082 Pseudomonas aeruginosa LpxD Complex Structure with Ligand 2019-09-20 2019-11-13 Kroeck, K.G.,Sacco, M.D.,Smith, E.W.,Zhang, X.,Shoun, D.,Akhtar, A.,Darch, S.E.,Cohen, F.,Andrews, L.D.,Knox, J.E.,Chen, Y. Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography. Sci Rep 2019 9 15450 15450
6UED 31664082 Apo Pseudomonas aeruginosa LpxD Structure 2019-09-20 2019-11-13 Kroeck, K.G.,Sacco, M.D.,Smith, E.W.,Zhang, X.,Shoun, D.,Akhtar, A.,Darch, S.E.,Cohen, F.,Andrews, L.D.,Knox, J.E.,Chen, Y. Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography. Sci Rep 2019 9 15450 15450
6NEX 31702583 Fab fragment of anti-cocaine antibody h2E2 2018-12-18 2019-11-20 Tan, K.,Zhou, M.,Ahrendt, A.J.,Duke, N.E.C.,Tabaja, N.,Ball, W.J.,Kirley, T.L.,Norman, A.B.,Joachimiak, A.,Schiffer, M.,Wilton, R.,Pokkuluri, P.R. Structural analysis of free and liganded forms of the Fab fragment of a high-affinity anti-cocaine antibody, h2E2. Acta Crystallogr.,Sect.F 2019 75 697 706
6PSJ 35575456 Bazedoxifene in Complex with Y537S Estrogen Receptor Alpha Ligand Binding Domain 2019-07-12 2019-11-20 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
6PZ2 Crystal Structure of FolP (dihydropteroate synthase) from Colstridium difficile in the presence of pteroic acid 2019-07-31 2019-11-27 Girardi, N.M.,Thoden, J.B.,Holden, H.M. Crystal Structure of FolP (dihydropteroate synthase) from Colstridium difficile in the presence of pteroic acid To Be Published 0 0 0 0
6Q0A Crystal structure of MurA from Clostridium difficile, mutation C116D, n the presence of UDP-N-acetylmuramic acid 2019-08-01 2019-11-27 Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. Crystal structure of MurA from Clostridium difficile, mutation C116D, n the presence of UDP-N-acetylmuramic acid To Be Published 0 0 0 0
6Q0Y Crystal structure of MurA from Clostridium difficile, mutant C116S, in the presence of Uridine-Diphosphate-N-Acetylglucosamine 2019-08-02 2019-11-27 Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. Crystal structure of MurA from Clostridium difficile, mutant C116S, in the presence of Uridine-Diphosphate-N-Acetylglucosamine To Be Published 0 0 0 0
6Q11 Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID 2019-08-02 2019-11-27 Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID To Be Published 0 0 0 0
6NVT 31780261 Crystal structure of TLA-1 extended spectrum Beta-lactamase 2019-02-05 2019-12-11 Cifuentes-Castro, V.,Rodriguez-Almazan, C.,Silva-Sanchez, J.,Rudino-Pinera, E. The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochem.Biophys.Res.Commun. 2020 522 545 551
6NVU 31780261 Crystal structure of TLA-1 extended spectrum Beta-lactamase in complex with Clavulanic Acid 2019-02-05 2019-12-11 Cifuentes-Castro, V.,Rodriguez-Almazan, C.,Silva-Sanchez, J.,Rudino-Pinera, E. The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochem.Biophys.Res.Commun. 2020 522 545 551
6PQ8 31780261 Crystal structure of TLA-1 S70G extended spectrum Beta-lactamase in complex with clavulanic acid 2019-07-08 2019-12-11 Cifuentes-Castro, V.,Rodriguez-Almazan, C.,Silva-Sanchez, J.,Rudino-Pinera, E. The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochem.Biophys.Res.Commun. 2020 522 545 551
6PQ9 31780261 Crystal Structure of TLA-1 S70G extended spectrum Beta-lactamase 2019-07-08 2019-12-11 Cifuentes-Castro, V.,Rodriguez-Almazan, C.,Silva-Sanchez, J.,Rudino-Pinera, E. The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site. Biochem.Biophys.Res.Commun. 2020 522 545 551
6NIU 32015557 Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein 2018-12-31 2019-12-25 Dussupt, V.,Sankhala, R.S.,Gromowski, G.D.,Donofrio, G.,De La Barrera, R.A.,Larocca, R.A.,Zaky, W.,Mendez-Rivera, L.,Choe, M.,Davidson, E.,McCracken, M.K.,Brien, J.D.,Abbink, P.,Bai, H.,Bryan, A.L.,Bias, C.H.,Berry, I.M.,Botero, N.,Cook, T.,Doria-Rose, N.A.,Escuer, A.G.I.,Frimpong, J.A.,Geretz, A.,Hernandez, M.,Hollidge, B.S.,Jian, N.,Kabra, K.,Leggat, D.J.,Liu, J.,Pinto, A.K.,Rutvisuttinunt, W.,Setliff, I.,Tran, U.,Townsley, S.,Doranz, B.J.,Rolland, M.,McDermott, A.B.,Georgiev, I.S.,Thomas, R.,Robb, M.L.,Eckels, K.H.,Barranco, E.,Koren, M.,Smith, D.R.,Jarman, R.G.,George, S.L.,Stephenson, K.E.,Barouch, D.H.,Modjarrad, K.,Michael, N.L.,Joyce, M.G.,Krebs, S.J. Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat. Med. 2020 26 228 235
6V87 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen 2019-12-10 2019-12-25 Fanning, S.W. Estrogen Receptor Alpha To Be Published 0 0 0 0
6V8T 35575456 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with LSZ102 2019-12-12 2019-12-25 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
6V2T 31867814 X-ray structure of a sugar N-formyltransferase from Shewanella sp FDAARGOS_354 2019-11-25 2020-01-08 Girardi, N.M.,Thoden, J.B.,Holden, H.M. Misannotations of the genes encoding sugar N-formyltransferases. Protein Sci. 2020 29 930 940
6V33 31867814 X-ray structure of a sugar N-formyltransferase from Pseudomonas congelans 2019-11-25 2020-01-08 Girardi, N.M.,Thoden, J.B.,Holden, H.M. Misannotations of the genes encoding sugar N-formyltransferases. Protein Sci. 2020 29 930 940
6PT1 31872762 Crystal Structure of Class D Beta-lactamase OXA-48 with Meropenem 2019-07-14 2020-01-22 Akhtar, A.,Pemberton, O.A.,Chen, Y. Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase. Acs Infect Dis. 2020 6 261 271
6PTU 31872762 Crystal Structure of Class D Beta-lactamase OXA-48 with Imipenem 2019-07-16 2020-01-22 Akhtar, A.,Pemberton, O.A.,Chen, Y. Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase. Acs Infect Dis. 2020 6 261 271
6V3T 31967772 X-Ray Crystal Structure of Tribolium castaneum Arylalkylamine N-acyltransferase in Complex with Acetyl-CoA 2019-11-26 2020-02-05 O'Flynn, B.G.,Lewandowski, E.M.,Prins, K.C.,Suarez, G.,McCaskey, A.N.,Rios-Guzman, N.M.,Anderson, R.L.,Shepherd, B.A.,Gelis, I.,Leahy, J.W.,Chen, Y.,Merkler, D.J. Characterization of ArylalkylamineN-Acyltransferase fromTribolium castaneum: An Investigation into a Potential Next-Generation Insecticide Target. Acs Chem.Biol. 2020 15 513 523
6VI7 32732435 Probing extradiol dioxygenase mechanism in NAD(+) biosynthesis by viewing reaction cycle intermediates - a substrate bidentately bound structure 2020-01-12 2020-02-12 Wang, Y.,Liu, K.F.,Yang, Y.,Davis, I.,Liu, A. Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA 2020 117 19720 19730
6VLO 32083779 X-ray Structure of the R141 Sugar 4,6-dehydratase from Acanthamoeba polyphaga Minivirus 2020-01-24 2020-03-04 Ferek, J.D.,Thoden, J.B.,Holden, H.M. Biochemical analysis of a sugar 4,6-dehydratase from Acanthamoeba polyphaga Mimivirus. Protein Sci. 2020 29 1148 1159
6W4B The crystal structure of Nsp9 RNA binding protein of SARS CoV-2 2020-03-10 2020-03-18 Tan, K.,Kim, Y.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Michalska, K.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) The crystal structure of Nsp9 replicase protein of COVID-19 To Be Published 0 0 0 0
6V1O 32150407 Structure of OXA-48 bound to QPX7728 at 1.80 A 2019-11-20 2020-03-25 Hecker, S.J.,Reddy, K.R.,Lomovskaya, O.,Griffith, D.C.,Rubio-Aparicio, D.,Nelson, K.,Tsivkovski, R.,Sun, D.,Sabet, M.,Tarazi, Z.,Parkinson, J.,Totrov, M.,Boyer, S.H.,Glinka, T.W.,Pemberton, O.A.,Chen, Y.,Dudley, M.N. Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-beta-lactamases. J.Med.Chem. 2020 63 7491 7507
6W2Z Crystal Structure of the Beta Lactamase Class A PenP from Bacillus subtilis in the Complex with the Non-beta- lactam Beta-lactamase Inhibitor Avibactam 2020-03-08 2020-03-25 Kim, Y.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Beta Lactamase Class A PenP from Bacillus subtilis in the Complex with the Non-beta- lactam Beta-lactamase Inhibitor Avibactam To Be Published 0 0 0 0
6VO6 32168450 Crystal Structure of Cj1427, an Essential NAD-dependent Dehydrogenase from Campylobacter jejuni, in the Presence of NADH and GDP 2020-01-30 2020-04-01 Huddleston, J.P.,Anderson, T.K.,Spencer, K.D.,Thoden, J.B.,Raushel, F.M.,Holden, H.M. Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides ofCampylobacter jejuni. Biochemistry 2020 59 1314 1327
6WIF Class C beta-lactamase from Acinetobacter baumannii in complex with 4-(Ethyl(methyl)carbamoyl)phenyl boronic acid 2020-04-09 2020-04-22 Chang, C.,Maltseva, N.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) class C beta-lactamase from Acinetobacter baumannii in complex with 4-(Ethyl(methyl)carbamoyl)phenyl boronic acid To Be Published 0 0 0 0
6UPI Crystal structure of Mycobacterium tuberculosis CYP121 bound with a hydroxylated intermediate of cYF-4-OMe 2019-10-17 2020-04-29 Nguyen, R.C.,Yang, Y.,Davis, I.,Liu, A. Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121 Acs Catalysis 2020 10 1628 1639
6VR1 32518267 Complex of HLA-A2, a class I MHC, with a p53 peptide 2020-02-06 2020-06-10 Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun 2020 11 2908 2908
6VR5 32518267 Complex of HLA-A2, a class I MHC, with a p53 peptide 2020-02-06 2020-06-17 Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun 2020 11 2908 2908
6VRN 32518267 T cell receptor-p53-HLA-A2 complex 2020-02-08 2020-06-17 Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun 2020 11 2908 2908
6VTC 32518267 p53-specific T cell receptor 2020-02-12 2020-06-17 Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun 2020 11 2908 2908
6X9Y The crystal structure of a Beta-lactamase from Escherichia coli CFT073 2020-06-03 2020-06-17 Tan, K.,Wu, R.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) The crystal structure of a Beta-lactamase from Escherichia coli CFT073 To Be Published 0 0 0 0
6OOJ 32774871 CTX-M-14 Beta Lactamase with Compound 14 2019-04-23 2020-07-01 DeFrees, K.,Kemp, M.T.,ElHilali-Pollard, X.,Zhang, X.,Mohamed, A.,Chen, Y.,Renslo, A.R. An Empirical Study of Amide-Heteroarene pi-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase. Org Chem Front 2019 6 1749 1756
6OOK 32774871 CTX-M-14 Beta Lactamase with Compound 3 2019-04-23 2020-07-01 DeFrees, K.,Kemp, M.T.,ElHilali-Pollard, X.,Zhang, X.,Mohamed, A.,Chen, Y.,Renslo, A.R. An Empirical Study of Amide-Heteroarene pi-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase. Org Chem Front 2019 6 1749 1756
6PLL 31043568 Crystal structure of the ZIG-8 IG1 homodimer 2019-07-01 2020-07-08 Cheng, S.,Park, Y.,Kurleto, J.D.,Jeon, M.,Zinn, K.,Thornton, J.W.,Ozkan, E. Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence. Proc. Natl. Acad. Sci. U.S.A. 2019 116 9837 9842
6S0W 32592631 The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel and kanamycin B sulfate 2019-06-18 2020-07-08 Mrugala, B.,Milaczewska, A.,Porebski, P.J.,Niedzialkowska, E.,Guzik, M.,Minor, W.,Borowski, T. A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J. 2021 288 1366 1386
6S0W 32592631 The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel and kanamycin B sulfate 2019-06-18 2020-07-08 Mrugala, B.,Milaczewska, A.,Porebski, P.J.,Niedzialkowska, E.,Guzik, M.,Minor, W.,Borowski, T. A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J. 2021 288 1366 1386
6XFS Class C beta-lactamase from Escherichia coli in complex with Tazobactam 2020-06-16 2020-07-15 Chang, C.,Maltseva, N.,Endres, M.,Joachimiak, A. Class C beta-lactamase from Escherichia coli in complex with Tazobactam To Be Published 0 0 0 0
6PWQ 32553967 Crystal structure of Levansucrase from Bacillus subtilis mutant S164A at 2.6 A 2019-07-23 2020-07-22 Ortiz-Soto, M.E.,Porras-Dominguez, J.R.,Rodriguez-Alegria, M.E.,Morales-Moreno, L.A.,Diaz-Vilchis, A.,Rudino-Pinera, E.,Beltran-Hernandez, N.E.,Rivera, H.M.,Seibel, J.,Lopez Munguia, A. Implications of the mutation S164A on Bacillus subtilis levansucrase product specificity and insights into protein interactions acting upon levan synthesis. Int.J.Biol.Macromol. 2020 161 898 908
6VI6 32732435 Observing a ring-cleaving dioxygenase in action through a crystalline lens - a substrate monodentately bound structure 2020-01-12 2020-07-29 Wang, Y.,Liu, K.F.,Yang, Y.,Davis, I.,Liu, A. Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA 2020 117 19720 19730
6VI8 32732435 Observing a ring-cleaving dioxygenase in action through a crystalline lens - a superoxo bound structure 2020-01-12 2020-07-29 Wang, Y.,Liu, K.F.,Yang, Y.,Davis, I.,Liu, A. Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA 2020 117 19720 19730
6VI9 32732435 Observing a ring-cleaving dioxygenase in action through a crystalline lens - an alkylperoxo bound structure 2020-01-12 2020-07-29 Wang, Y.,Liu, K.F.,Yang, Y.,Davis, I.,Liu, A. Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA 2020 117 19720 19730
6PZL P. mirabilis hemolysin A mutant - Q125A 2019-08-01 2020-08-05 Weaver, T.M.,Novak, W.R.P.,Grilley, D.P.,Wimmer, M.R.,Woods, C.N.,Bhattacharyya, B. Structure of the HpmA265 Q125A variant To Be Published 0 0 0 0
6Q0P P. mirabilis hemolysin A mutant - Y134S 2019-08-02 2020-08-05 Weaver, T.M.,Novak, W.R.P.,Grilley, D.P.,Wimmer, M.R.,Woods, C.N.,Bhattacharyya, B. Structure of the HpmA265 Q125A variant To Be Published 0 0 0 0
7JRN 34341772 Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 2020-08-12 2020-08-26 Ma, C.,Sacco, M.D.,Xia, Z.,Lambrinidis, G.,Townsend, J.A.,Hu, Y.,Meng, X.,Szeto, T.,Ba, M.,Zhang, X.,Gongora, M.,Zhang, F.,Marty, M.T.,Xiang, Y.,Kolocouris, A.,Chen, Y.,Wang, J. Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci. 2021 7 1245 1260
6VPF 35575456 Estrogen Receptor Alpha Ligand Binding Domain in Complex with the Selective Estrogen Receptor Modulator Clomiphene 2020-02-03 2020-09-16 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7JH4 32887719 Crystal structure of NAD(P)H-flavin oxidoreductase (NfoR) from S. aureus complexed with reduced FMN and NAD+ 2020-07-20 2020-09-16 O'Neill, A.G.,Beaupre, B.A.,Zheng, Y.,Liu, D.,Moran, G.R. NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? Appl.Environ.Microbiol. 2020 86 0 0
6UXZ 32557944 (S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR 2019-11-09 2020-10-07 Catlin, D.S.,Reidl, C.T.,Trzupek, T.R.,Silverman, R.B.,Cannon, B.L.,Becker, D.P.,Liu, D. (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR. Protein Sci. 2020 29 1816 1828
7C28 33000863 Unusual quaternary structure of a homodimeric synergistic toxin from mamba snake venom 2020-05-07 2020-10-14 Aoki-Shioi, N.,Jobichen, C.,Sivaraman, J.,Kini, R.M. Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution. Biochem.J. 2020 477 3951 3962
6OL1 Structure of VcINDY in complex with Succinate 2019-04-15 2020-10-28 Klinz-Thompson, C.D.,Redondo, M.L.,Mulligan, C.,Sauer, D.B.,Marden, J.J.,Song, J.,Tajkhorshid, E.,Hunt, J.F.,Stokes, D.L.,Mindell, J.A.,Wang, D.N.,Gonzalez, R.L. Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter Biorxiv 2022 0 0 0
7KBS 35575456 Estrogen Receptor Alpha Ligand Binding Domain in Complex with Raloxifene 2020-10-02 2020-11-18 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
6WEX 33495478 Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H6 Hemagglutinin 2020-04-03 2020-11-25 Harshbarger, W.D.,Deming, D.,Lockbaum, G.J.,Attatippaholkun, N.,Kamkaew, M.,Hou, S.,Somasundaran, M.,Wang, J.P.,Finberg, R.W.,Zhu, Q.K.,Schiffer, C.A.,Marasco, W.A. Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun 2021 12 559 559
6WEZ 33495478 Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin 2020-04-03 2020-11-25 Harshbarger, W.D.,Deming, D.,Lockbaum, G.J.,Attatippaholkun, N.,Kamkaew, M.,Hou, S.,Somasundaran, M.,Wang, J.P.,Finberg, R.W.,Zhu, Q.K.,Schiffer, C.A.,Marasco, W.A. Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun 2021 12 559 559
6WF0 33495478 Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin 2020-04-03 2020-11-25 Harshbarger, W.D.,Deming, D.,Lockbaum, G.J.,Attatippaholkun, N.,Kamkaew, M.,Hou, S.,Somasundaran, M.,Wang, J.P.,Finberg, R.W.,Zhu, Q.K.,Schiffer, C.A.,Marasco, W.A. Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun 2021 12 559 559
7JHD 33177154 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with TTC-352 and GRIP Peptide 2020-07-20 2020-11-25 Abderrahman, B.,Maximov, P.Y.,Curpan, R.F.,Fanning, S.W.,Hanspal, J.S.,Fan, P.,Foulds, C.E.,Chen, Y.,Malovannaya, A.,Jain, A.,Xiong, R.,Greene, G.L.,Tonetti, D.A.,Thatcher, G.R.J.,Jordan, V.C. Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol.Cancer Ther. 2021 20 11 25
7KPP 33912589 Structure of the E102A mutant of a GNAT superfamily PA3944 acetyltransferase 2020-11-12 2020-11-25 Baumgartner, J.T.,Habeeb Mohammad, T.S.,Czub, M.P.,Majorek, K.A.,Arolli, X.,Variot, C.,Anonick, M.,Minor, W.,Ballicora, M.A.,Becker, D.P.,Kuhn, M.L. Gcn5-Related N- Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too. Front Mol Biosci 2021 8 646046 646046
7DH6 33239170 Crystal structure of PLRG1 2020-11-13 2020-12-02 Wang, X.,Li, Y.,Dai, H.,Xu, C. Crystal structure of the WD40 domain of human PLRG1. Biochem.Biophys.Res.Commun. 2021 534 474 477
6LKB 33098102 Crystal Structure of the peptidylprolyl isomerase domain of Arabidopsis thaliana CYP71. 2019-12-18 2020-12-16 Lakhanpal, S.,Fan, J.S.,Luan, S.,Swaminathan, K. Structural and functional analyses of the PPIase domain of Arabidopsis thaliana CYP71 reveal its catalytic activity toward histone H3. Febs Lett. 2021 595 145 154
7KYE Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES 2020-12-07 2020-12-16 Czub, M.P.,Porebski, P.J.,Cymborowski, M.,Minor, W. Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES To Be Published 0 0 0 0
7KYJ Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc 2020-12-07 2020-12-16 Czub, M.P.,Porebski, P.J.,Cymborowski, M.,Shabalin, I.G.,Minor, W. Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc To Be Published 0 0 0 0
7JWS 33341649 Crystal structure of human ALDH1A1 bound to compound (R)-28 2020-08-26 2020-12-30 Huddle, B.C.,Grimley, E.,Chtcherbinine, M.,Buchman, C.D.,Takahashi, C.,Debnath, B.,McGonigal, S.C.,Mao, S.,Li, S.,Felton, J.,Pan, S.,Wen, B.,Sun, D.,Neamati, N.,Buckanovich, R.J.,Hurley, T.D.,Larsen, S.D. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem. 2020 211 113060 113060
7JWT 33341649 Crystal structure of human ALDH1A1 bound to compound (R)-28 2020-08-26 2020-12-30 Huddle, B.C.,Grimley, E.,Chtcherbinine, M.,Buchman, C.D.,Takahashi, C.,Debnath, B.,McGonigal, S.C.,Mao, S.,Li, S.,Felton, J.,Pan, S.,Wen, B.,Sun, D.,Neamati, N.,Buckanovich, R.J.,Hurley, T.D.,Larsen, S.D. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem. 2020 211 113060 113060
7JWU 33341649 Crystal structure of human ALDH1A1 bound to compound (R)-28 2020-08-26 2020-12-30 Huddle, B.C.,Grimley, E.,Chtcherbinine, M.,Buchman, C.D.,Takahashi, C.,Debnath, B.,McGonigal, S.C.,Mao, S.,Li, S.,Felton, J.,Pan, S.,Wen, B.,Sun, D.,Neamati, N.,Buckanovich, R.J.,Hurley, T.D.,Larsen, S.D. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem. 2020 211 113060 113060
7JWV 33341649 Crystal structure of human ALDH1A1 bound to compound (R)-28 2020-08-26 2020-12-30 Huddle, B.C.,Grimley, E.,Chtcherbinine, M.,Buchman, C.D.,Takahashi, C.,Debnath, B.,McGonigal, S.C.,Mao, S.,Li, S.,Felton, J.,Pan, S.,Wen, B.,Sun, D.,Neamati, N.,Buckanovich, R.J.,Hurley, T.D.,Larsen, S.D. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem. 2020 211 113060 113060
7JWW 33341649 Crystal structure of human ALDH1A1 bound to compound (R)-28 2020-08-26 2020-12-30 Huddle, B.C.,Grimley, E.,Chtcherbinine, M.,Buchman, C.D.,Takahashi, C.,Debnath, B.,McGonigal, S.C.,Mao, S.,Li, S.,Felton, J.,Pan, S.,Wen, B.,Sun, D.,Neamati, N.,Buckanovich, R.J.,Hurley, T.D.,Larsen, S.D. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem. 2020 211 113060 113060
7L5D 34285133 The crystal structure of SARS-CoV-2 Main Protease in complex with demethylated analog of masitinib 2020-12-21 2020-12-30 Drayman, N.,DeMarco, J.K.,Jones, K.A.,Azizi, S.A.,Froggatt, H.M.,Tan, K.,Maltseva, N.I.,Chen, S.,Nicolaescu, V.,Dvorkin, S.,Furlong, K.,Kathayat, R.S.,Firpo, M.R.,Mastrodomenico, V.,Bruce, E.A.,Schmidt, M.M.,Jedrzejczak, R.,Munoz-Alia, M.A.,Schuster, B.,Nair, V.,Han, K.Y.,O'Brien, A.,Tomatsidou, A.,Meyer, B.,Vignuzzi, M.,Missiakas, D.,Botten, J.W.,Brooke, C.B.,Lee, H.,Baker, S.C.,Mounce, B.C.,Heaton, N.S.,Severson, W.E.,Palmer, K.E.,Dickinson, B.C.,Joachimiak, A.,Randall, G.,Tay, S. Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2. Science 2021 373 931 936
6VE5 34174285 X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74) 2019-12-28 2021-01-13 Du Truong, C.,Craig, T.A.,Cui, G.,Botuyan, M.V.,Serkasevich, R.A.,Chan, K.Y.,Mer, G.,Chiu, P.L.,Kumar, R. Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta. J.Biol.Chem. 2021 297 100912 100912
7K12 33369426 ACMSD in complex with diflunisal 2020-09-07 2021-01-13 Yang, Y.,Borel, T.,de Azambuja, F.,Johnson, D.,Sorrentino, J.P.,Udokwu, C.,Davis, I.,Liu, A.,Altman, R.A. Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. J.Med.Chem. 2021 64 797 811
7K13 33369426 ACMSD in complex with diflunisal derivative 14 2020-09-07 2021-01-13 Yang, Y.,Borel, T.,de Azambuja, F.,Johnson, D.,Sorrentino, J.P.,Udokwu, C.,Davis, I.,Liu, A.,Altman, R.A. Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. J.Med.Chem. 2021 64 797 811
7LGP DapE enzyme from Shigella flexneri 2021-01-20 2021-01-27 Osipiuk, J.,Endres, M.,Becker, D.P.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) DapE enzyme from Shigella flexneri To Be Published 0 0 0 0
6XLR 33091303 The 1.23 Angstrom crystal structure of galactose oxidase variant with genetically incorporated Cl2-Tyr272 2020-06-29 2021-02-03 Li, J.,Davis, I.,Griffith, W.P.,Liu, A. Formation of Monofluorinated Radical Cofactor in Galactose Oxidase through Copper-Mediated C-F Bond Scission. J.Am.Chem.Soc. 2020 142 18753 18757
6XLT 33091303 The 1.48 Angstrom crystal structure of evolved galactose oxidase variant A3.E7 2020-06-29 2021-02-03 Li, J.,Davis, I.,Griffith, W.P.,Liu, A. Formation of Monofluorinated Radical Cofactor in Galactose Oxidase through Copper-Mediated C-F Bond Scission. J.Am.Chem.Soc. 2020 142 18753 18757
7LFZ Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL 2021-01-19 2021-02-03 Patskovska, L.,Patskovsky, Y.,Krogsgaard, M. Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL To Be Published 0 0 0 0
7LG0 Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope SPRWYFYYL 2021-01-19 2021-02-03 Patskovska, L.,Patskovsky, Y.,Krogsgaard, M. Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope SPRWYFYYL To Be Published 0 0 0 0
7LG2 Human leukocyte antigen A*0201 in complex with SARS-CoV2 epitope ALWEIQQVV 2021-01-19 2021-02-03 Patskovska, L.,Patskovsky, Y.,Krogsgaard, M. Human leukocyte antigen A*0201 in complex with SARS-CoV2 epitope ALWEIQQVV To Be Published 0 0 0 0
7LG3 Human leukocyte antigen A*0201 in complex with SARS-CoV2 epitope KLWAQCVQL 2021-01-19 2021-02-03 Patskovska, L.,Patskovsky, Y.,Krogsgaard, M. Human leukocyte antigen A*0201 in complex with SARS-CoV2 epitope KLWAQCVQL To Be Published 0 0 0 0
6U6M 34086838 Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH840.1 2019-08-30 2021-03-24 Cai, F.,Chen, W.H.,Wu, W.,Jones, J.A.,Choe, M.,Gohain, N.,Shen, X.,LaBranche, C.,Eaton, A.,Sutherland, L.,Lee, E.M.,Hernandez, G.E.,Wu, N.R.,Scearce, R.,Seaman, M.S.,Moody, M.A.,Santra, S.,Wiehe, K.,Tomaras, G.D.,Wagh, K.,Korber, B.,Bonsignori, M.,Montefiori, D.C.,Haynes, B.F.,de Val, N.,Joyce, M.G.,Saunders, K.O. Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog. 2021 17 0 0
6U6O 34086838 Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846 2019-08-30 2021-03-24 Cai, F.,Chen, W.H.,Wu, W.,Jones, J.A.,Choe, M.,Gohain, N.,Shen, X.,LaBranche, C.,Eaton, A.,Sutherland, L.,Lee, E.M.,Hernandez, G.E.,Wu, N.R.,Scearce, R.,Seaman, M.S.,Moody, M.A.,Santra, S.,Wiehe, K.,Tomaras, G.D.,Wagh, K.,Korber, B.,Bonsignori, M.,Montefiori, D.C.,Haynes, B.F.,de Val, N.,Joyce, M.G.,Saunders, K.O. Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog. 2021 17 0 0
7M13 33900734 Crystal structure of CJ1428, a GDP-D-GLYCERO-L-GLUCO-HEPTOSE SYNTHASE from campylobacter jejuni in the presence of NADPH 2021-03-12 2021-03-24 Huddleston, J.P.,Anderson, T.K.,Girardi, N.M.,Thoden, J.B.,Taylor, Z.,Holden, H.M.,Raushel, F.M. Biosynthesis of d- glycero -l- gluco -Heptose in the Capsular Polysaccharides of Campylobacter jejuni . Biochemistry 2021 60 1552 1563
6WAS 34559844 Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold 2020-03-26 2021-03-31 Aljedani, S.S.,Liban, T.J.,Tran, K.,Phad, G.,Singh, S.,Dubrovskaya, V.,Pushparaj, P.,Martinez-Murillo, P.,Rodarte, J.,Mileant, A.,Mangala Prasad, V.,Kinzelman, R.,O'Dell, S.,Mascola, J.R.,Lee, K.K.,Karlsson Hedestam, G.B.,Wyatt, R.T.,Pancera, M. Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog. 2021 17 0 0
7KQS 33734681 A 1.68-A resolution 3-fluoro-L-tyrosine bound crystal structure of heme-dependent tyrosine hydroxylase 2020-11-17 2021-03-31 Wang, Y.,Davis, I.,Shin, I.,Xu, H.,Liu, A. Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase. J.Am.Chem.Soc. 2021 143 4680 4693
7KQU 33734681 A 1.58-A resolution crystal structure of ferric-hydroperoxo intermediate of L-tyrosine hydroxylase in complex with 3-fluoro-L-tyrosine 2020-11-17 2021-03-31 Wang, Y.,Davis, I.,Shin, I.,Xu, H.,Liu, A. Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase. J.Am.Chem.Soc. 2021 143 4680 4693
7LIN 34144977 X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide 2021-01-27 2021-04-14 Wang, D.,Ma, J.,Botuyan, M.V.,Cui, G.,Yan, Y.,Ding, D.,Zhou, Y.,Krueger, E.W.,Pei, J.,Wu, X.,Wang, L.,Pei, H.,McNiven, M.A.,Ye, D.,Mer, G.,Huang, H. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv 2021 7 0 0
7LIO 34144977 X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide 2021-01-27 2021-04-14 Wang, D.,Ma, J.,Botuyan, M.V.,Cui, G.,Yan, Y.,Ding, D.,Zhou, Y.,Krueger, E.W.,Pei, J.,Wu, X.,Wang, L.,Pei, H.,McNiven, M.A.,Ye, D.,Mer, G.,Huang, H. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv 2021 7 0 0
7LIP 34144977 X-ray structure of SPOP MATH domain (D140G) 2021-01-27 2021-04-14 Wang, D.,Ma, J.,Botuyan, M.V.,Cui, G.,Yan, Y.,Ding, D.,Zhou, Y.,Krueger, E.W.,Pei, J.,Wu, X.,Wang, L.,Pei, H.,McNiven, M.A.,Ye, D.,Mer, G.,Huang, H. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv 2021 7 0 0
7MBL Crystal structure of Equine Serum Albumin in complex with Cobalt (II) 2021-03-31 2021-04-14 Shabalin, I.G.,Czub, M.P.,Handing, K.B.,Grabowski, M.,Cooper, D.R.,Minor, W. Crystal structure of Equine Serum Albumin in complex with Cobalt To Be Published 0 0 0 0
6WK4 Fab Fragment of Anti-human LAG3 antibody (13E2) 2020-04-15 2021-04-21 Agnihotri, P.,Mishra, A.K.,Mariuzza, R.A. Fab Fragment of Anti-human LAG3 antibody To Be Published 0 0 0 0
7LT8 33891945 Crystal structure of Ras suppressor-1 2021-02-19 2021-04-28 Fukuda, K.,Lu, F.,Qin, J. Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly. J.Biol.Chem. 2021 296 100685 100685
7LT9 33891945 Crystal structure of Ras suppressor-1 in complex with PINCH-1 LIM4-5 domains 2021-02-19 2021-04-28 Fukuda, K.,Lu, F.,Qin, J. Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly. J.Biol.Chem. 2021 296 100685 100685
7MFO 34076307 X-ray structure of the L136 Aminotransferase from Acanthamoeba polyphaga mimivirus in the presence of TDP and PMP 2021-04-10 2021-04-28 Seltzner, C.A.,Ferek, J.D.,Thoden, J.B.,Holden, H.M. Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus. Protein Sci. 2021 30 1882 1894
7MQV Crystal structure of truncated (ACT domain removed) prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD 2021-05-06 2021-05-19 Shabalin, I.G.,Hou, J.,Christendat, D.,Minor, W. The crystal structure of Bacillus anthracis prephenate dehydrogenase identified an ACT regulatory domain and a novel mode of metabolic regulation for proteins within the prephenate dehydrogenase family of enzyme to be published 0 0 0 0
6WRB 35662248 Self-assembly of a 3D DNA crystal lattice (4x5 duplex version) containing the J5 immobile Holliday junction 2020-04-29 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
6XDW 35662248 Self-assembly of a 3D DNA crystal lattice (4x5 junction version) containing the J5 immobile Holliday junction 2020-06-11 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JH8 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 junction version) containing the J20 immobile Holliday junction 2020-07-20 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JH9 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 junction version) containing the J22 immobile Holliday junction 2020-07-20 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JHB 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 junction version) containing the J24 immobile Holliday junction 2020-07-20 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JHC 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 junction version) containing the J26 immobile Holliday junction 2020-07-20 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JOK 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 duplex version) containing the J26 immobile Holliday junction 2020-08-06 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JOL 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 duplex version) containing the J24 immobile Holliday junction 2020-08-06 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JP5 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 duplex version) containing the J22 immobile Holliday junction 2020-08-07 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7JP6 35662248 Self-assembly of a 3D DNA crystal lattice (4x6 duplex version) containing the J20 immobile Holliday junction 2020-08-07 2021-07-14 Simmons, C.R.,MacCulloch, T.,Krepl, M.,Matthies, M.,Buchberger, A.,Crawford, I.,Sponer, J.,Sulc, P.,Stephanopoulos, N.,Yan, H. The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly. Nat Commun 2022 13 3112 3112
7KLZ 34599168 Structure of SPOP MATH domain in complex with a Geminin peptide 2020-11-01 2021-08-18 Ma, J.,Shi, Q.,Cui, G.,Sheng, H.,Botuyan, M.V.,Zhou, Y.,Yan, Y.,He, Y.,Wang, L.,Wang, Y.,Mer, G.,Ye, D.,Wang, C.,Huang, H. SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition. Nat Commun 2021 12 5779 5779
7LNM 34014654 Ornithine Aminotransferase (OAT) cocrystallized with its inactivator - (1S,3S)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid 2021-02-07 2021-08-25 Zhu, W.,Doubleday, P.F.,Butrin, A.,Weerawarna, P.M.,Melani, R.D.,Catlin, D.S.,Dwight, T.A.,Liu, D.,Kelleher, N.L.,Silverman, R.B. Remarkable and Unexpected Mechanism for ( S )-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase. J.Am.Chem.Soc. 2021 143 8193 8207
7JTA 34644300 Crystal structure of a putative nuclease with anti-Cas9 activity from an uncultured Clostridia bacterium 2020-08-17 2021-09-22 Forsberg, K.J.,Schmidtke, D.T.,Werther, R.,Uribe, R.V.,Hausman, D.,Sommer, M.O.A.,Stoddard, B.L.,Kaiser, B.K.,Malik, H.S. The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity. Plos Biol. 2021 19 0 0
7S1A Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae Rd KW20 2021-09-01 2021-10-06 Maltseva, N.,Kim, Y.,Endres, M.,Crofts, T.,Joachimiak, A. Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae Rd KW20 To Be Published 0 0 0 0
7KAE Rop protein variant with a buried tryptophan 2020-09-30 2021-10-13 Hoopes, J.T.,Karageorgos, I.,Gallagher, D.T. Structure of a Rop protein variant with a buried tryptophan To be published 0 0 0 0
7SGW Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder630 inhibitor 2021-10-07 2021-10-20 Osipiuk, J.,Tesar, C.,Endres, M.,Lisnyak, V.,Maki, S.,Taylor, C.,Zhang, Y.,Zhou, Z.,Azizi, S.A.,Jones, K.,Kathayat, R.,Snyder, S.A.,Dickinson, B.C.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder630 inhibitor To Be Published 0 0 0 0
7KRY 34870992 Co-crystal structure of alpha glucosidase with compound 11 2020-11-20 2021-12-01 Karade, S.S.,Hill, M.L.,Kiappes, J.L.,Manne, R.,Aakula, B.,Zitzmann, N.,Warfield, K.L.,Treston, A.M.,Mariuzza, R.A. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem. 2021 64 18010 18024
7T85 Crystal Structure of the N-terminal Domain of the Phosphate Acetyltransferase from Escherichia coli 2021-12-15 2021-12-29 Kim, Y.,Dementiev, A.,Welk, L.,Endres, M.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the N-terminal Domain of the Phosphate Acetyltransferase from Escherichia coli To Be Published 0 0 0 0
7TE7 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with RAD1901 2022-01-04 2022-01-19 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
7TEM Crystal Structure of the Putative Exported Protein YPO2471 from Yersinia pestis 2022-01-05 2022-01-19 Kim, Y.,Chhor, G.,Endres, M.,Babnigg, G.,Schneewind, O.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Putative Exported Protein YPO2471 from Yersinia pestis To Be Published 0 0 0 0
7TG5 Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK in the Presence of Fe Ion from Yersinia pestis 2022-01-07 2022-01-19 Kim, Y.,Chhor, G.,Endres, M.,Babnigg, G.,Schneewind, O.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK in the presence of Fe ion from Yersinia pestis To Be Published 0 0 0 0
7TJ1 Crystal Structure of the Putative Fluoride Ion Transporter CrcB Bab1_1389 from Brucella abortus 2022-01-14 2022-01-26 Kim, Y.,Tesar, C.,Pastore, T.,Endres, M.,Babnigg, G.,Crosson, S.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Putative Fluoride Ion Transporter CrcB Bab1_1389 from Brucella abortus To Be Published 0 0 0 0
7STA 35156805 X-ray Crystal Structure of Truncated Human Chemokine CCL19 (7-70) 2021-11-12 2022-02-23 Lewandowski, E.M.,Kroeck, K.G.,Jacobs, L.M.C.,Fenske, T.G.,Witt, R.N.,Hintz, A.M.,Ramsden, E.R.,Zhang, X.,Peterson, F.,Volkman, B.F.,Veldkamp, C.T.,Chen, Y. Structural Insights into Molecular Recognition by Human Chemokine CCL19. Biochemistry 2022 61 311 318
7MG0 Crystal structure of EV-D68 2A protease 2021-04-12 2022-04-13 Liu, C.,Lee, M.-Y.,Ma, C.,Liu, W.,Wang, J. Crystal structure of EV-D68 2A protease To Be Published 0 0 0 0
7UNN 36787356 Thiol-disulfide oxidoreductase TsdA from Corynebacterium diphtheriae 2022-04-11 2022-04-20 Reardon-Robinson, M.E.,Nguyen, M.T.,Sanchez, B.C.,Osipiuk, J.,Ruckert, C.,Chang, C.,Chen, B.,Nagvekar, R.,Joachimiak, A.,Tauch, A.,Das, A.,Ton-That, H. A cryptic oxidoreductase safeguards oxidative protein folding in Corynebacterium diphtheriae. Proc.Natl.Acad.Sci.USA 2023 120 0 0
7TVY 35568118 Short form D7 protein from Culex quinquefasciatus 2022-02-06 2022-05-25 Alvarenga, P.H.,Dias, D.R.,Xu, X.,Francischetti, I.M.B.,Gittis, A.G.,Arp, G.,Garboczi, D.N.,Ribeiro, J.M.C.,Andersen, J.F. Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes. Insect Biochem.Mol.Biol. 2022 146 103785 103785
7UJ8 35575456 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen 2022-03-30 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJC 35575456 Raloxifene in Complex with Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutation 2022-03-30 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJF 35575456 Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative with Selective Estrogen Receptor Degrader Properties 2022-03-30 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJM 35575456 Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative That Increases Receptor Resonance Time in the Nucleus of Breast Cancer Cells 2022-03-31 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJO 35575456 Estrogen Receptor Alpha Ligand Binding Domain in Complex with RU39411 2022-03-31 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJW 35575456 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with a Methylated Lasofoxifene Derivative that Possesses Selective Estrogen Receptor Degrader Activities 2022-03-31 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7UJY 35575456 Estrogen receptor alpha ligand binding domain Y537S mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time 2022-03-31 2022-06-15 Hosfield, D.J.,Weber, S.,Li, N.S.,Suavage, M.,Joiner, C.F.,Hancock, G.R.,Sullivan, E.A.,Ndukwe, E.,Han, R.,Cush, S.,Laine, M.,Mader, S.C.,Greene, G.L.,Fanning, S.W. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife 2022 11 0 0
7N9J Crystal structure of H2DB in complex with HSF2 melanoma neoantigen 2021-06-18 2022-06-22 Patskovsky, Y.,Finnigan, J.,Patskovska, L.,Newman, J.,Bhardwaj, N.,Krogsgaard, M. Structure of the complex between H2DB and melanoma HSF2 neoantigen YGFRNVVHI To be Published 0 0 0 0
7NA5 Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen 2021-06-19 2022-06-22 Patskovsky, Y.,Finnigan, J.,Patskovska, L.,Newman, J.,Bhardwaj, N.,Krogsgaard, M. Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI To be Published 0 0 0 0
7RKE 35859859 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide 2021-07-22 2022-06-22 Sammeta, V.R.,Norris, J.D.,Artham, S.,Torrice, C.D.,Byemerwa, J.,Joiner, C.,Fanning, S.W.,McDonnell, D.P.,Willson, T.M. A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core. Acs Med.Chem.Lett. 2022 13 1151 1158
7T2X 35859859 Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 2-chloro-4-((4-hydroxybenzyl)amino)-5-phenylthieno[2,3-d]pyrimidin-6-ol and GRIP Peptide 2021-12-06 2022-06-22 Sammeta, V.R.,Norris, J.D.,Artham, S.,Torrice, C.D.,Byemerwa, J.,Joiner, C.,Fanning, S.W.,McDonnell, D.P.,Willson, T.M. A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core. Acs Med.Chem.Lett. 2022 13 1151 1158
7N9O Estrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15) 2021-06-18 2022-07-06 Fanning, S.W.,Mader, S.C. Estrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15) To Be Published 0 0 0 0
7R62 Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Desmethyl ICI164,384 Derivative 2021-06-22 2022-07-06 Fanning, S.W. Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Desmethyl ICI164,384 Derivative To Be Published 0 0 0 0
7T5Z 35653508 P. aeruginosa LpxA in complex with ligand L8 2021-12-13 2022-07-06 Sacco, M.D.,Defrees, K.,Zhang, X.,Lawless, W.,Nwanochie, E.,Balsizer, A.,Darch, S.E.,Renslo, A.R.,Chen, Y. Structure-Based Ligand Design Targeting Pseudomonas aeruginosa LpxA in Lipid A Biosynthesis. Acs Infect Dis. 2022 8 1231 1240
7RAE AncAR1 - progesterone - Tif2 2021-07-01 2022-07-27 Ortlund, E.A. AncAR1 - DHT - Tif2 To Be Published 0 0 0 0
7RNM Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 2-(2-Chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)isoindolin-5-ol and GRIP Peptide 2021-07-29 2022-08-03 Reddy Sammeta, V.,Anderson, B.M.,Norris, J.D.,Torrice, C.D.,Joiner, C.,Liu, S.,Li, H.,Popov, K.I.,Fanning, S.W.,McDonnell, D.P.,Willson, T.M. Structural Determinants of the Binding and Activation of Estrogen Receptor alpha by Phenolic Thieno[2,3-d]pyrimidines Helv.Chim.Acta 2023 106 0 0
7RCU 36302987 Synthetic Max homodimer mimic in complex with DNA 2021-07-08 2022-09-14 Speltz, T.E.,Qiao, Z.,Swenson, C.S.,Shangguan, X.,Coukos, J.S.,Lee, C.W.,Thomas, D.M.,Santana, J.,Fanning, S.W.,Greene, G.L.,Moellering, R.E. Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. Nat.Biotechnol. 2023 41 541 551
8EBG Crystal structure of the probable FhuD FeIII-dicitrate-binding domain protein FecB from Mycobacterium tuberculosis 2022-08-31 2022-09-14 Cuff, M.,Kim, Y.,Endres, M.,Gu, M.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) Crystal structure of the probable FhuD FeIII-dicitrate-binding domain protein FecB from Mycobacterium tuberculosis To Be Published 0 0 0 0
7SFO Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide 2021-10-04 2022-10-12 Fanning, S.W. Estrogen Receptor Alpha To Be Published 0 0 0 0
8EP7 Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in complex with NADP 2022-10-05 2022-10-19 Kim, Y.,Maltseva, N.,Osipiuk, J.,Gu, M.,Joachimiak, A. Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in the complex with NADP. To Be Published 0 0 0 0
7S8E 37353482 STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE AND BOUND GLYCEROL 2021-09-17 2022-11-02 Patskovsky, Y.,Natarajan, A.,Patskovska, L.,Nyovanie, S.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.B.,Findeis, M.A.,Hurwitz, A.,Van Dijk, M.,Chantzoura, E.,Yague, A.S.,Pollack Smith, D.,Buell, J.S.,Underwood, D.,Krogsgaard, M. Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun 2023 14 3763 3763
7S8F 37353482 STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE AND BOUND GLYCEROL 2021-09-17 2022-11-02 Patskovsky, Y.,Natarajan, A.,Patskovska, L.,Nyovanie, S.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.B.,Findeis, M.A.,Hurwitz, A.,Van Dijk, M.,Chantzoura, E.,Yague, A.S.,Pollack Smith, D.,Buell, J.S.,Underwood, D.,Krogsgaard, M. Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun 2023 14 3763 3763
7S8I 37353482 PHOSPHOPEPTIDE-SPECIFIC LC13 TCR, MONOCLINIC CRYSTAL FORM 2021-09-17 2022-11-02 Patskovsky, Y.,Natarajan, A.,Patskovska, L.,Nyovanie, S.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.B.,Findeis, M.A.,Hurwitz, A.,Van Dijk, M.,Chantzoura, E.,Yague, A.S.,Pollack Smith, D.,Buell, J.S.,Underwood, D.,Krogsgaard, M. Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun 2023 14 3763 3763
7SO8 Crystal structure of Glutathione S-Transferase from Shrimp Litopenaeus vannamei in complex with silver ions and a molecules of Glutathione binding in G-site and H-site 2021-10-29 2022-11-02 Escudero-Garcia, A.,Rudino-Pinera, E. Inhibition of GST class Mu of the shrimp Litopenaeus vannamei by binding silver ions in H-site. To Be Published 0 0 0 0
7SMG 36989297 Crystal structure of a (p)ppApp hydrolase from Bacteroides caccae 2021-10-25 2022-11-09 Ahmad, S.,Gordon, I.J.,Tsang, K.K.,Alexei, A.G.,Sychantha, D.,Colautti, J.,Trilesky, S.L.,Kim, Y.,Wang, B.,Whitney, J.C. Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp. Proc.Natl.Acad.Sci.USA 2023 120 0 0
8DU6 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (1'-(4-((1-ethylazetidin-3-yl)oxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DU8 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6-hydroxy-1-(4-((1-propylazetidin-3-yl)oxy)phenyl)-3,4-dihydroisoquinolin-2(1H)-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DU9 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3,4-dihydroisoquinolin-2(1H)-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUC 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (1'-(4-(2-(1-ethylpyrrolidin-3-yl)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUD 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-(1-propylpyrrolidin-3-yl)ethoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUG 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-((S)-3-methylpyrrolidin-1-yl)ethoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUH 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-((R)-2-methylpyrrolidin-1-yl)ethoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUI 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (1'-(4-(2-(dimethylamino)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUS 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (1'-(4-(2-(ethylamino)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DV5 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-((1-pentylpyrrolidin-3-yl)methoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-28 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DV7 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-(1-propylpyrrolidin-3-yl)ethyl)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-28 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DV8 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-((2-(1-propylpyrrolidin-3-yl)ethyl)thio)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-28 2022-11-09 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DUB 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with ((1'-(4-((1-ethylpyrrolidin-3-yl)methyl)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2022-11-16 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8DVB 36517522 Estrogen Receptor Alpha Ligand Binding Domain in Complex with (1'-(4-((1-butylpyrrolidin-3-yl)methoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-28 2022-11-16 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildiz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer 2022 8 130 130
8E62 36346293 STRUCTURE OF Pcryo_0615 from Psychrobacter cryohalolentis, an N-acetyltransferase required to produce Diacetamido-2,3-dideoxy-D-glucuronic acid 2022-08-22 2022-11-23 Hofmeister, D.L.,Seltzner, C.A.,Bockhaus, N.J.,Thoden, J.B.,Holden, H.M. Investigation of the enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-d-glucuronic acid in Psychrobacter cryohalolentis K5 T. Protein Sci. 2023 32 0 0
8DCY 36435827 CCHFV GP38 Hoti/Kosovo bound with 13G8 Fab 2022-06-17 2022-12-07 Durie, I.A.,Tehrani, Z.R.,Karaaslan, E.,Sorvillo, T.E.,McGuire, J.,Golden, J.W.,Welch, S.R.,Kainulainen, M.H.,Harmon, J.R.,Mousa, J.J.,Gonzalez, D.,Enos, S.,Koksal, I.,Yilmaz, G.,Karakoc, H.N.,Hamidi, S.,Albay, C.,Spengler, J.R.,Spiropoulou, C.F.,Garrison, A.R.,Sajadi, M.M.,Bergeron, E.,Pegan, S.D. Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus. Nat Commun 2022 13 7298 7298
8DC5 36435827 CCHFV GP38 Hoti/Kosovo 2022-06-15 2022-12-14 Durie, I.A.,Tehrani, Z.R.,Karaaslan, E.,Sorvillo, T.E.,McGuire, J.,Golden, J.W.,Welch, S.R.,Kainulainen, M.H.,Harmon, J.R.,Mousa, J.J.,Gonzalez, D.,Enos, S.,Koksal, I.,Yilmaz, G.,Karakoc, H.N.,Hamidi, S.,Albay, C.,Spengler, J.R.,Spiropoulou, C.F.,Garrison, A.R.,Sajadi, M.M.,Bergeron, E.,Pegan, S.D. Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus. Nat Commun 2022 13 7298 7298
8F5K 36542812 Azurin from Pseudomonas aeruginosa, Y72F/Y108F/F110A mutant 2022-11-14 2023-01-04 Tyson, K.,Tangtartharakul, C.B.,Zeug, M.,Findling, N.,Haddy, A.,Hvastkovs, E.,Choe, J.Y.,Kim, J.E.,Offenbacher, A.R. Electrochemical and Structural Study of the Buried Tryptophan in Azurin: Effects of Hydration and Polarity on the Redox Potential of W48. J.Phys.Chem.B 2023 127 133 143
8F5L 36542812 Azurin from Pseudomonas aeruginosa, Y72F/Y108F/F110L mutant 2022-11-14 2023-01-04 Tyson, K.,Tangtartharakul, C.B.,Zeug, M.,Findling, N.,Haddy, A.,Hvastkovs, E.,Choe, J.Y.,Kim, J.E.,Offenbacher, A.R. Electrochemical and Structural Study of the Buried Tryptophan in Azurin: Effects of Hydration and Polarity on the Redox Potential of W48. J.Phys.Chem.B 2023 127 133 143
8EX0 36678572 Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with CDK2-IV 2022-10-24 2023-02-01 Virtanen, A.T.,Haikarainen, T.,Sampathkumar, P.,Palmroth, M.,Liukkonen, S.,Liu, J.,Nekhotiaeva, N.,Hubbard, S.R.,Silvennoinen, O. Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain. Pharmaceuticals 2023 16 0 0
8EX1 36678572 Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with Reversine 2022-10-24 2023-02-01 Virtanen, A.T.,Haikarainen, T.,Sampathkumar, P.,Palmroth, M.,Liukkonen, S.,Liu, J.,Nekhotiaeva, N.,Hubbard, S.R.,Silvennoinen, O. Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain. Pharmaceuticals 2023 16 0 0
8EX2 36678572 Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with HTSA3 2022-10-24 2023-02-01 Virtanen, A.T.,Haikarainen, T.,Sampathkumar, P.,Palmroth, M.,Liukkonen, S.,Liu, J.,Nekhotiaeva, N.,Hubbard, S.R.,Silvennoinen, O. Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain. Pharmaceuticals 2023 16 0 0
7WX5 36048151 a Legionella acetyltransferase effector VipF 2022-02-14 2023-02-22 Chen, T.T.,Lin, Y.,Zhang, S.,Han, A. Structural basis for the acetylation mechanism of the Legionella effector VipF. Acta Crystallogr D Struct Biol 2022 78 1110 1119
7UA7 Crystal structure of indoline 9 with KPC-2 2022-03-11 2023-03-15 DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R. Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors To Be Published 0 0 0 0
8GHY 37548665 Crystal Structure of the E154D mutant CelD Cellulase from the Anaerobic Fungus Piromyces finnis in the complex with cellotriose. 2023-03-13 2023-05-17 Dementiev, A.,Lillington, S.P.,Jin, S.,Kim, Y.,Jedrzejczak, R.,Michalska, K.,Joachimiak, A.,O'Malley, M.A. Structure and enzymatic characterization of CelD endoglucanase from the anaerobic fungus Piromyces finnis. Appl.Microbiol.Biotechnol. 2023 107 5999 6011
8CTT Crystal structure of a K+ selective NaK mutant (NaK2K) at 100K 2022-05-16 2023-06-14 Lee, B.,White, K.I.,Socolich, M.A.,Klureza, M.A.,Henning, R.,Srajer, V.,Ranganathan, R.,Hekstra, D. Direct visualization of electric field-stimulated ion conduction in a potassium channel To Be Published 0 0 0 0
7TEU 37290440 Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1 2022-01-05 2023-06-21 Arwood, M.L.,Liu, Y.,Harkins, S.K.,Weinstock, D.M.,Yang, L.,Stevenson, K.E.,Plana, O.D.,Dong, J.,Cirka, H.,Jones, K.L.,Virtanen, A.T.,Gupta, D.G.,Ceas, A.,Lawney, B.,Yoda, A.,Leahy, C.,Hao, M.,He, Z.,Choi, H.G.,Wang, Y.,Silvennoinen, O.,Hubbard, S.R.,Zhang, T.,Gray, N.S.,Li, L.S. New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chem Biol 2023 30 618 0
8DUK Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-(methylamino)ethoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone 2022-07-27 2023-07-05 Hancock, G.R.,Young, K.S.,Hosfield, D.J.,Joiner, C.,Sullivan, E.A.,Yildz, Y.,Laine, M.,Greene, G.L.,Fanning, S.W. Estrogen Receptor Alpha Ligand Binding Domain in Complex with (6'-hydroxy-1'-(4-(2-(methylamino)ethoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone To Be Published 0 0 0 0
7ULX Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine 2022-04-05 2023-08-30 Tuley, A.,Zheng, Y.,Tommasi, S.,Butrin, A.,May, K.V.,Ahn, Y.,Reidl, T.C.,Weerakoon, L.,Hulin, J.,Meech, R.,Patel, D.S.,Horton, C.P.,Swartzel, C.J.,Kim, Y.,Silverman, B.R.,Mangoni, A.,Liu, D.,Fast, W. Optimization of a switchable electrophile fragment into a potent and selective covalent inhibitor of human DDAH1 To Be Published 0 0 0 0
8EF3 37561630 Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D 2022-09-07 2023-08-30 Sankhala, R.S.,Dussupt, V.,Donofrio, G.,Gromowski, G.D.,De La Barrera, R.A.,Larocca, R.A.,Mendez-Rivera, L.,Lee, A.,Choe, M.,Zaky, W.,Mantus, G.,Jensen, J.L.,Chen, W.H.,Gohain, N.,Bai, H.,McCracken, M.K.,Mason, R.D.,Leggat, D.,Slike, B.M.,Tran, U.,Jian, N.,Abbink, P.,Peterson, R.,Mendes, E.A.,Freitas de Oliveira Franca, R.,Calvet, G.A.,Bispo de Filippis, A.M.,McDermott, A.,Roederer, M.,Hernandez, M.,Albertus, A.,Davidson, E.,Doranz, B.J.,Rolland, M.,Robb, M.L.,Lynch, R.M.,Barouch, D.H.,Jarman, R.G.,Thomas, S.J.,Modjarrad, K.,Michael, N.L.,Krebs, S.J.,Joyce, M.G. Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep 2023 42 112942 112942
8TTP Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam 2023-08-14 2023-09-06 Chang, C.,Maltseva, N.,Endres, M.,Joachimiak, A. Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam to be published 0 0 0 0
8SFY Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with UDP-glucose 2023-04-11 2023-09-13 Arriaza, R.H.,Daneshian, L.,Dermauw, W.,Wybouw, N.,Van Leeuwen, T.,Chruszcz, M. Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with UDP-glucose To Be Published 0 0 0 0
8U4U 37773238 Crystal structure of 53BP1 tandem Tudor domain homodimer engineered with two disulfide bridges 2023-09-11 2023-09-20 Cui, G.,Botuyan, M.V.,Drane, P.,Hu, Q.,Bragantini, B.,Thompson, J.R.,Schuller, D.J.,Detappe, A.,Perfetti, M.T.,James, L.I.,Frye, S.V.,Chowdhury, D.,Mer, G. An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nat Commun 2023 14 6091 6091
8V15 Human SIRT3 bound to p53-AMC peptide, Carba-NAD, and Honokiol 2023-11-19 2023-12-06 Chakrabarti, R.,Ghosh, A.,Guan, X.,Upadhyay, A.,Dumpati, R.K.,Munshi, S.,Roy, S.,Chall, S.,Rahnamoun, A.,Reverdy, C.,Errasti, G.,Delacroix, T. Computationally Driven Discovery and Characterization of SIRT3 Activating Compounds that Fully Recover Catalytic Activity under NAD+ Depletion biorxiv 2023 0 0 0
8CZP 2.25 angstrom resolution crystal structure of as-isolated KatG from Mycobacterium tuberculosis with an MYW cofactor 2022-05-25 2023-12-13 Li, J.,Liu, A. 2.25 angstrom resolution crystal structure of as-isolated KatG from Mycobacterium tuberculosis with an MYW cofactor To Be Published 0 0 0 0
8UQ8 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 2-residue linker 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQ9 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQA 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQB 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1) 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQC 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 2) 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQD 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (condition 2. RING not modeled in density) 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8UQE 38242129 Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density) 2023-10-23 2024-01-17 Hu, Q.,Zhao, D.,Cui, G.,Bhandari, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell 2024 84 839 0
8TPB 38192109 Synthesis, X-Ray Crystallographic and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease 2023-08-04 2024-01-24 Ashraf-Uz-Zaman, M.,Chua, T.K.,Li, X.,Yao, Y.,Moku, B.K.,Mishra, C.B.,Avadhanula, V.,Piedra, P.A.,Song, Y. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. Acs Infect Dis. 2024 10 715 731
8TPC 38192109 Synthesis, X-Ray Crystallographic and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease 2023-08-04 2024-01-24 Ashraf-Uz-Zaman, M.,Chua, T.K.,Li, X.,Yao, Y.,Moku, B.K.,Mishra, C.B.,Avadhanula, V.,Piedra, P.A.,Song, Y. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. Acs Infect Dis. 2024 10 715 731
8TPD 38192109 Synthesis, X-Ray Crystallographic and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease 2023-08-04 2024-01-24 Ashraf-Uz-Zaman, M.,Chua, T.K.,Li, X.,Yao, Y.,Moku, B.K.,Mishra, C.B.,Avadhanula, V.,Piedra, P.A.,Song, Y. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. Acs Infect Dis. 2024 10 715 731
8TPF 38192109 Synthesis, X-Ray Crystallographic and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease 2023-08-04 2024-01-24 Ashraf-Uz-Zaman, M.,Chua, T.K.,Li, X.,Yao, Y.,Moku, B.K.,Mishra, C.B.,Avadhanula, V.,Piedra, P.A.,Song, Y. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. Acs Infect Dis. 2024 10 715 731
8VR2 Crystal structure of the Pcryo_0617 oxidoreductase/decarboxylase from Psychrobacter cryohalolentis K5 in the presence of NAD and UDP 2024-01-20 2024-01-31 Bockhaus, N.J.,Dunsirn, M.M.,Thoden, J.B.,Holden, H.M. Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published 0 0 0 0
8VR6 crystal structure of the Pcryo_0619 N-acetryltransferase from Psychrobacter cryohalolentis K5 in the presence of CoA-disulfide 2024-01-20 2024-01-31 Bockhaus, N.J.,Dunsirn, M.M.,Thoden, J.B.,Holden, H.M. Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published 0 0 0 0
8VRM Crystal structure of the Pcryo_0619 N-acetyltransferase from Psychrobacter cryohalolentis K5 2024-01-22 2024-01-31 Bockhaus, N.J.,Dunsirn, M.M.,Thoden, J.B.,Holden, H.M. Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published 0 0 0 0
8SZ6 38327055 PmHMGR bound to mevaldehyde and CoA 2023-05-27 2024-03-20 Purohit, V.,Steussy, C.N.,Rosales, A.R.,Critchelow, C.J.,Schmidt, T.,Helquist, P.,Wiest, O.,Mesecar, A.,Cohen, A.E.,Stauffacher, C.V. pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography. Biophys.J. 2024 123 622 637