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The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody To be Published 0 0 0 0 1GWE 12454454 Atomic resolution structure of Micrococcus Lysodeikticus catalase 2002-03-15 2002-04-26 Murshudov, G.N.,Grebenko, A.I.,Brannigan, J.A.,Antson, A.A.,Barynin, V.V.,Dodson, G.G.,Dauter, Z.,Wilson, K.S.,Melik-Adamyan, W.R. The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex. Acta Crystallogr.,Sect.D 2002 58 1972 1982 481D 11829600 CRYSTAL STRUCTURE OF A HEXITOL NUCLEIC ACID (HNA) DUPLEX AT 1.6A RESOLUTION 1999-07-23 2002-04-27 Declercq, R.,Van Aerschot, A.,Read, R.J.,Herdewijn, P.,Van Meervelt, L. Crystal structure of double helical hexitol nucleic acids. J.Am.Chem.Soc. 2002 124 928 933 1H4G 10381409 Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre 2001-05-11 2002-05-09 Sabini, E.,Sulzenbacher, G.,Dauter, M.,Dauter, Z.,Jorgensen, P.L.,Schulein, M.,Dupont, C.,Davies, G.J.,Wilson, K.S. Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase. Chem.Biol. 1999 6 483 0 1GL7 11214325 Plasmid coupling protein TrwB in complex with the non-hydrolisable ATP-analogue ADPNP. 2001-08-28 2002-05-16 Gomis-Ruth, F.X.,Moncalian, G.,Perez-Luque, R.,Gonzalez, A.,Cabezon, E.,De La Cruz, F.,Coll, M. The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase Nature 2001 409 637 0 1JUH 11839311 Crystal Structure of Quercetin 2,3-dioxygenase 2001-08-24 2002-05-22 Fusetti, F.,Schroter, K.H.,Steiner, R.A.,van Noort, P.I.,Pijning, T.,Rozeboom, H.J.,Kalk, K.H.,Egmond, M.R.,Dijkstra, B.W. Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus. Structure 2002 10 259 268 1GYO 12657783 Crystal structure of the di-tetraheme cytochrome c3 from Desulfovibrio gigas at 1.2 Angstrom resolution 2002-04-29 2002-05-24 Aragao, D.,Frazao, C.,Sieker, L.,Sheldrick, G.M.,Legall, J.,Carrondo, M.A. Structure of Dimeric Cytochrome C3 from Desulfovibrio Gigas at 1.2 A Resolution Acta Crystallogr.,Sect.D 2003 59 644 0 1KO5 12054802 Crystal structure of gluconate kinase 2001-12-20 2002-05-29 Kraft, L.,Sprenger, G.A.,Lindqvist, Y. Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. J.Mol.Biol. 2002 318 1057 1069 1I5E 12037295 CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP 2001-02-27 2002-06-05 Kadziola, A.,Neuhard, J.,Larsen, S. Structure of product-bound Bacillus caldolyticus uracil phosphoribosyltransferase confirms ordered sequential substrate binding. Acta Crystallogr.,Sect.D 2002 58 936 945 1JVW 11751578 TRYPANOSOMA CRUZI MACROPHAGE INFECTIVITY POTENTIATOR (TCMIP) 2001-08-31 2002-06-05 Pereira, P.J.,Vega, M.C.,Gonzalez-Rey, E.,Fernandez-Carazo, R.,Macedo-Ribeiro, S.,Gomis-Ruth, F.X.,Gonzalez, A.,Coll, M. Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix. EMBO Rep. 2002 3 88 94 1LYC 12777760 The impact of the physical and chemical enviroment on the molecular structure of Coprinus cinereus peroxidase 2002-06-07 2002-06-14 Houborg, K.,Harris, P.,Petersen, J.,Rowland, P.,Poulsen, J.C.,Schneider, P.,Vind, J.,Larsen, S. 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J.Biol.Chem. 2002 277 10647 10652 1JKU 11587647 Crystal Structure of Manganese Catalase from Lactobacillus plantarum 2001-07-13 2002-07-13 Barynin, V.V.,Whittaker, M.M.,Antonyuk, S.V.,Lamzin, V.S.,Harrison, P.M.,Artymiuk, P.J.,Whittaker, J.W. Crystal structure of manganese catalase from Lactobacillus plantarum. Structure 2001 9 725 738 1L1Y 12096911 The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum cellulosome 2002-02-20 2002-07-17 Guimaraes, B.G.,Souchon, H.,Lytle, B.L.,David Wu, J.H.,Alzari, P.M. The crystal structure and catalytic mechanism of cellobiohydrolase CelS, the major enzymatic component of the Clostridium thermocellum Cellulosome. J.Mol.Biol. 2002 320 587 596 1GZZ 12135360 Human Insulin-like growth factor; Hamburg data 2002-06-10 2002-07-25 Brzozowski, A.M.,Dodson, E.J.,Dodson, G.G.,Murshudov, G.,Verma, C.,Turkenburg, J.P.,De Bree, F.M.,Dauter, Z. Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry 2002 41 9389 0 1M5H 12192072 Formylmethanofuran:tetrahydromethanopterin formyltransferase from Archaeoglobus fulgidus 2002-07-09 2002-07-26 Mamat, B.,Roth, A.,Grimm, C.,Ermler, U.,Tziatzios, C.,Schubert, D.,Thauer, R.K.,Shima, S. Crystal structures and enzymatic properties of three formyltransferases from archaea: environmental adaptation and evolutionary relationship. Protein Sci. 2002 11 2168 2178 1JTL 12071949 The crystal structure of d(GGCCAATTGG) Complexed with Distamycin 2001-08-21 2002-08-09 Uytterhoeven, K.,Sponer, J.,Van Meervelt, L. Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG). Eur.J.Biochem. 2002 269 2868 2877 1KSU 12093271 Crystal Structure of His505Tyr Mutant Flavocytochrome c3 from Shewanella frigidimarina 2002-01-14 2002-08-14 Pankhurst, K.L.,Mowat, C.G.,Miles, C.S.,Leys, D.,Walkinshaw, M.D.,Reid, G.A.,Chapman, S.K. Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina. Biochemistry 2002 41 8551 8556 1H2J 12595701 ENDOGLUCANASE CEL5A IN COMPLEX WITH UNHYDROLYSED AND COVALENTLY LINKED 2,4-DINITROPHENYL-2-DEOXY-2-FLUORO-CELLOBIOSIDE AT 1.15 A RESOLUTION 2002-08-09 2002-08-15 Varrot, A.,Davies, G.J. Direct Experimental Observation of the Hydrogen-Bonding Network of a Glycosidase Along its Reaction Coordinate Revealed by Atomic Resolution Analyses of Endoglucanase Cel5A Acta Crystallogr.,Sect.D 2003 59 447 0 1GYC 12163489 CRYSTAL STRUCTURE DETERMINATION AT ROOM TEMPERATURE OF A LACCASE FROM TRAMETES VERSICOLOR IN ITS OXIDISED FORM CONTAINING A FULL COMPLEMENT OF COPPER IONS 2002-04-23 2002-08-22 Piontek, K.,Antorini, M.,Choinowski, T. Crystal Structure of a Laccase from the Fungus Trametes Versicolor at 1.90-A Resolution Containing a Full Complement of Coppers. J.Biol.Chem. 2002 277 37663 0 1GXT 12206761 Hydrogenase Maturation Protein HypF ""acylphosphatase-like"" N-terminal domain (HypF-ACP) in complex with Sulfate 2002-04-11 2002-09-12 Rosano, C.,Zuccotti, S.,Bucciantini, M.,Stefani, M.,Ramponi, G.,Bolognesi, M. Crystal Structure and Anion Binding in the Prokaryotic Hydrogenase Maturation Factor Hypf Acylphosphatase-Like Domain J.Mol.Biol. 2002 321 785 0 1M5E 12215417 X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH ACPA AT 1.46 A RESOLUTION 2002-07-09 2002-09-18 Hogner, A.,Kastrup, J.S.,Jin, R.,Liljefors, T.,Mayer, M.L.,Egebjerg, J.,Larsen, I.K.,Gouaux, E. Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core J.Mol.Biol. 2002 322 93 109 1GPP 12235380 Crystal structure of the S.cerevisiae Homing Endonuclease PI-SceI Domain I 2001-11-07 2002-09-19 Werner, E.,Wende, W.,Pingoud, A.,Heinemann, U. 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J.Biol.Chem. 2006 281 5804 5810 1Q9E 15005620 RNase T1 variant with adenine specificity 2003-08-25 2004-03-23 Czaja, R.,Struhalla, M.,Saenger, W.,Hahn, U. RNase T1 Variant RV Cleaves Single-Stranded RNA after Purines Due to Specific Recognition by the Asn46 Side Chain Amide. Biochemistry 2004 43 2854 2862 1S07 14756557 Crystal Structure of the R253A Mutant of 7,8-Diaminopelargonic Acid Synthase 2003-12-30 2004-03-23 Sandmark, J.,Eliot, A.C.,Famm, K.,Schneider, G.,Kirsch, J.F. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry 2004 43 1213 1222 1NXD 15159564 Crystal structure of MnMn Concanavalin A 2003-02-10 2004-03-30 Lopez-Jaramillo, F.J.,Gonzalez-Ramirez, L.A.,Albert, A.,Santoyo-Gonzalez, F.,Vargas-Berenguel, A.,Otalora, F. Structure of concanavalin A at pH 8: bound solvent and crystal contacts. Acta Crystallogr.,Sect.D 2004 60 1048 1056 1OIH 15023059 Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase 2003-06-18 2004-03-30 Mueller, I.,Kahnert, A.,Pape, T.,Sheldrick, G.M.,Meyer-Klaucke, W.,Dierks, T.,Kertesz, M.,Uson, I. Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) -Ketoglutarate-Dependent Dioxygenase Superfamily Biochemistry 2004 42 3075 0 1PZ8 15016366 Modulation of agrin function by alternative splicing and Ca2+ binding 2003-07-10 2004-04-13 Stetefeld, J.,Alexandrescu, A.T.,Maciejewski, M.W.,Jenny, M.,Rathgeb-Szabo, K.,Schulthess, T.,Landwehr, R.,Frank, S.,Ruegg, M.A.,Kammerer, R.A. Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE 2004 12 503 515 1PZ9 15016366 Modulation of agrin function by alternative splicing and Ca2+ binding 2003-07-10 2004-04-13 Stetefeld, J.,Alexandrescu, A.T.,Maciejewski, M.W.,Jenny, M.,Rathgeb-Szabo, K.,Schulthess, T.,Landwehr, R.,Frank, S.,Ruegg, M.A.,Kammerer, R.A. Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE 2004 12 503 515 1OFR 15019786 CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE 2003-04-18 2004-04-15 Koenig, V.,Pfeil, A.,Heinrich, G.,Braus, G.,Schneider, T.R. Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism. J.Mol.Biol. 2004 337 675 0 1OG0 CRYSTAL STRUCTURE OF THE MUTANT G226S OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE 2003-04-22 2004-04-30 Koenig, V.,Pfeil, A.,Heinrich, G.,Braus, G.H.,Schneider, T.R. Crystal Structure of the Mutant G226S of the Tyrosine-Regulated 3-Deoxy-D-Arabino-Heptulosonate -7-Phosphate Synthase from Saccharomyces Cerevisiae Complexed with Phenylalanine and Manganese To be Published 0 0 0 0 1VJ7 15066282 Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis. 2004-02-03 2004-05-04 Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response. Cell(Cambridge,Mass.) 2004 117 57 68 1OF6 crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with tyrosine and manganese 2003-04-08 2004-05-06 Koenig, V.,Pfeil, A.,Heinrich, G.,Braus, G.,Schneider, T.R. Crystal Structure of the Double Complex of the Tyrosine Sensitive Dahp Synthase from Yeast To be Published 0 0 0 0 1UU0 15007066 Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (Apo-form) 2003-12-12 2004-05-13 Fernandez, F.J.,Vega, M.C.,Lehmann, F.,Sandmeier, E.,Gehring, H.,Christen, P.,Wilmanns, M. Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem. 2004 279 21478 0 1OF0 CRYSTAL STRUCTURE OF BACILLUS SUBTILIS COTA AFTER 1H SOAKING WITH ABTS 2003-04-03 2004-05-21 Enguita, F.J.,Marcal, D.,Grenha, R.,Martins, L.O.,Henriques, A.O.,Carrondo, M.A. Structural Characterization of a Bacterial Laccase Reaction Cycle To be Published 0 0 0 0 1OF1 15163659 KINETICS AND CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (SOUTH)-METHANOCARBA-THYMIDINE 2003-04-03 2004-06-03 Schelling, P.,Claus, M.T.,Johner, R.,Marquez, V.E.,Schulz, G.E.,Scapozza, L. Biochemical and Structural Characterization of (South)-Methanocarbathymidine that Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-Transduced Osteosarcoma Cells J.Biol.Chem. 2004 279 32832 0 1PJX 14501113 0.85 ANGSTROM STRUCTURE OF SQUID GANGLION DFPASE 2003-06-04 2004-06-08 Koepke, J.,Scharff, E.I.,Lucke, C.,Ruterjans, H.,Fritzsch, G. Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 A resolution. Acta Crystallogr.,Sect.D 2003 59 1744 1754 1OI8 15215524 5'-Nucleotidase (E. coli) with an Engineered Disulfide Bridge (P90C, L424C) 2003-06-10 2004-06-10 Schultz-Heienbrok, R.,Maier, T.,Straeter, N. Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges Protein Sci. 2004 13 1811 0 1PXU 15694127 Crystal structure of chicken NtA from a eukaryotic source at 2.2A resolution 2003-07-07 2004-06-29 Mascarenhas, J.B.,Ruegg, M.A.,Sasaki, T.,Eble, J.A.,Engel, J.,Stetefeld, J. Structure and laminin-binding specificity of the NtA domain expressed in eukaryotic cells. Matrix Biol. 2005 23 507 513 1SCK 14998991 K236L mutant of hydroxynitrile lyase from Hevea brasiliensis in complex with acetone 2004-02-12 2004-06-29 Gruber, K.,Gartler, G.,Krammer, B.,Schwab, H.,Kratky, C. Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236 J.Biol.Chem. 2004 279 20501 20510 1R0K 15063313 Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Zymomonas mobilis 2003-09-22 2004-07-13 Ricagno, S.,Grolle, S.,Bringer-Meyer, S.,Sahm, H.,Lindqvist, Y.,Schneider, G. Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution. Biochim.Biophys.Acta 2004 1698 37 44 1UXN 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-02-27 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXP 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-02-27 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXQ 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-03-01 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXR 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-03-01 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXT 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-03-01 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXU 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-03-01 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1UXV 15288789 Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 2004-03-01 2004-08-05 Lorentzen, E.,Hensel, R.,Knura, T.,Ahmed, H.,Pohl, E. Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol. 2004 341 815 0 1SYL 15208312 Crystal structure of inactive mutant dUTPase complexed with substrate dUTP 2004-04-01 2004-09-07 Barabas, O.,Pongracz, V.,Kovari, J.,Wilmanns, M.,Vertessy, B.G. Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase J.Biol.Chem. 2004 279 42907 42915 1XFP 15383540 Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme 2004-09-15 2004-09-28 De Genst, E.,Handelberg, F.,Van Meirhaeghe, A.,Vynck, S.,Loris, R.,Wyns, L.,Muyldermans, S. Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody J.Biol.Chem. 2004 279 53593 53601 1SZ6 MISTLETOE LECTIN I FROM VISCUM ALBUM. CRYSTAL STRUCTURE AT 2.05 A RESOLUTION 2004-04-04 2004-10-05 Gabdoulkhakov, A.G.,Guhlistova, N.E.,Lyashenko, A.V.,Krauspenhaar, R.,Stoeva, S.,Voelter, W.,Nikonov, S.V.,Betzel, C.,Mikhailov, A.M. Crystal Structure of Viscum album Mistletoe Lectin I in native state at 2.05 A resolution, comparison of structure active site conformation in ricin and in viscumin TO BE PUBLISHED 0 0 0 0 1Q9H 15560790 3-Dimensional structure of native Cel7A from Talaromyces emersonii 2003-08-25 2004-11-09 Grassick, A.,Murray, P.G.,Thompson, R.,Collins, C.M.,Byrnes, L.,Birrane, G.,Higgins, T.M.,Tuohy, M.G. Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii Eur.J.Biochem. 2004 271 4495 4506 1URJ 15507432 Single stranded DNA-binding protein(ICP8) from Herpes simplex virus-1 2003-10-30 2004-11-11 Mapelli, M.,Panjikar, S.,Tucker, P.A. The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J. Biol. Chem. 2005 280 2990 2997 1R45 ADP-ribosyltransferase C3bot2 from Clostridium botulinum, triclinic form 2003-10-03 2004-11-16 Teplyakov, A.,Obmolova, G.,Gilliland, G.L.,Narumiya, S. Crystal structure of ADP-ribosyltransferase C3bot2 from Clostridium botulinum To be Published 0 0 0 0 1W0D 15663922 The high resolution structure of Mycobacterium tuberculosis LeuB (Rv2995c) 2004-06-03 2004-12-14 Singh, R.K.,Kefala, G.,Janowski, R.,Mueller-Dieckmann, C.,Von Kries, J.P.,Weiss, M.S. The High Resolution Structure of Leub (Rv2995C) from Mycobacterium Tuberculosis J.Mol.Biol. 2005 346 1 0 1RJC 15659390 Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme 2003-11-19 2005-02-01 De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J.Biol.Chem. 2005 280 14114 14121 1R6G 15177471 Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound 2003-10-15 2005-02-15 Hangeland, J.J.,Doweyko, A.M.,Dejneka, T.,Friends, T.J.,Devasthale, P.,Mellstrom, K.,Sandberg, J.,Grynfarb, M.,Sack, J.S.,Einspahr, H.,Farnegardh, M.,Husman, B.,Ljunggren, J.,Koehler, K.,Sheppard, C.,Malm, J.,Ryono, D.E. Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta. Bioorg.Med.Chem.Lett. 2004 14 3549 3553 1W19 15723519 Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate 2004-06-03 2005-03-02 Morgunova, E.,Meining, W.,Illarionov, B.,Haase, I.,Jin, G.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry 2005 44 2746 0 1W29 15723519 Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)butane 1-phosphate 2004-07-01 2005-03-03 Morgunova, E.,Meining, W.,Illarionov, B.,Haase, I.,Jin, G.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry 2005 44 2746 0 1W8S 15766250 The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates 2004-09-27 2005-03-23 Lorentzen, E.,Siebers, B.,Hensel, R.,Pohl, E. Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates. Biochemistry 2005 44 4222 4229 1XR9 17057332 Crystal Structures of HLA-B*1501 in Complex with Peptides from Human UbcH6 and Epstein-Barr Virus EBNA-3 2004-10-14 2005-04-14 Roder, G.,Blicher, T.,Justesen, S.,Johannesen, B.,Kristensen, O.,Kastrup, J.,Buus, S.,Gajhede, M. Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype Acta Crystallogr.,Sect.D 2006 62 1300 1310 1UVZ 16195549 structure of human thioredoxin 2 2004-01-27 2005-06-16 Smeets, A.,Evrard, C.,Landtmeters, M.,Marchand, C.,Knoops, B.,Declercq, J.P. Crystal Structures of Oxidized and Reduced Forms of Human Mitochondrial Thioredoxin 2. Protein Sci. 2005 14 2610 0 1HHF Decaplanin second P6122-Form 2000-12-22 2005-07-11 Lehmann, C.,Debreczeni, J.E.,Bunkoczi, G.,Dauter, M.,Dauter, Z.,Vertesy, L.,Sheldrick, G.M. Structures of Four Crystal Forms of Decaplanin Helv.Chim.Acta 2003 86 1478 0 1U0A 16483609 Crystal structure of the engineered beta-1,3-1,4-endoglucanase H(A16-M) in complex with beta-glucan tetrasaccharide 2004-07-13 2005-09-06 Gaiser, O.J.,Piotukh, K.,Ponnuswamy, M.N.,Planas, A.,Borriss, R.,Heinemann, U. Structural Basis for the Substrate Specificity of a Bacillus 1,3-1,4-beta-Glucanase J.Mol.Biol. 2006 357 1211 1225 1ZN2 16154086 Low Resolution Structure of Response Regulator StyR 2005-05-11 2005-09-27 Milani, M.,Leoni, L.,Rampioni, G.,Zennaro, E.,Ascenzi, P.,Bolognesi, M. An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism. STRUCTURE 2005 13 1289 1297 1W66 16735476 Structure of a lipoate-protein ligase b from Mycobacterium tuberculosis 2004-08-13 2005-12-08 Ma, Q.,Zhao, X.,Eddine, A.N.,Geerlof, A.,Li, X.,Cronan, J.E.,Kaufmann, S.H.,Wilmanns, M. 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Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa 2006 103 4586 4591 2EXH 16631196 Structure of the family43 beta-Xylosidase from geobacillus stearothermophilus 2005-11-08 2006-04-04 Brux, C.,Ben-David, A.,Shallom-Shezifi, D.,Leon, M.,Niefind, K.,Shoham, G.,Shoham, Y.,Schomburg, D. The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues. J.Mol.Biol. 2006 359 97 109 2FGO 16596388 Structure of the 2[4FE-4S] ferredoxin from Pseudomonas aeruginosa 2005-12-22 2006-04-18 Giastas, P.,Pinotsis, N.,Efthymiou, G.,Wilmanns, M.,Kyritsis, P.,Moulis, J.-M.,Mavridis, I.M. The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values. J.Biol.Inorg.Chem. 2006 11 445 458 2EZ8 16680160 Pyruvate oxidase variant F479W in complex with reaction intermediate 2-lactyl-thiamin diphosphate 2005-11-10 2006-04-25 Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. Nat.Chem.Biol. 2006 2 324 328 2EZ9 16680160 Pyruvate oxidase variant F479W in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate 2005-11-10 2006-04-25 Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. Nat.Chem.Biol. 2006 2 324 328 2EZT 16680160 Pyruvate oxidase variant F479W in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate 2005-11-10 2006-04-25 Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. 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Febs J. 2006 273 2161 2171 2BSC 16041081 E. coli F17a-G lectin domain complex with N-acetylglucosamine, high- resolution structure 2005-05-20 2006-05-24 Buts, L.,Wellens, A.,Van Molle, I.,Wyns, L.,Loris, R.,Lahmann, M.,Oscarson, S.,De Greve, H.,Bouckaert, J. Impact of Natural Variation in Bacterial F17G Adhesins on Crystallization Behaviour. Acta Crystallogr.,Sect.D 2005 61 1149 0 1WAA 19282960 IG27 protein domain 2004-10-25 2006-07-05 Stacklies, W.,Vega, M.C.,Wilmanns, M.,Grater, F. Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis. Plos Comput.Biol. 2009 5 306 0 2EZ1 16768450 Holo tyrosine phenol-lyase from Citrobacter freundii at pH 8.0 2005-11-10 2006-07-25 Milic, D.,Matkovic-Calogovic, D.,Demidkina, T.V.,Kulikova, V.V.,Sinitzina, N.I.,Antson, A.A. Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions Biochemistry 2006 45 7544 7552 2GDC 16826238 Structure of Vinculin VD1 / IpaA560-633 complex 2006-03-15 2006-08-08 Hamiaux, C.,van Eerde, A.,Parsot, C.,Broos, J.,Dijkstra, B.W. Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri. Embo Rep. 2006 7 794 799 2FZ6 16882996 Crystal structure of hydrophobin HFBI 2006-02-09 2006-08-15 Hakanpaa, J.M.,Szilvay, G.R.,Kaljunen, H.,Maksimainen, M.,Linder, M.,Rouvinen, J. Two crystal structures of Trichoderma reesei hydrophobin HFBI--The structure of a protein amphiphile with and without detergent interaction. Protein Sci. 2006 15 2129 2140 2GVM 16882996 Crystal structure of hydrophobin HFBI with detergent 2006-05-03 2006-08-15 Hakanpaa, J.M.,Szilvay, G.R.,Kaljunen, H.,Maksimainen, M.,Linder, M.,Rouvinen, J. Two crystal structures of Trichoderma reesei hydrophobin HFBI--The structure of a protein amphiphile with and without detergent interaction. Protein Sci. 2006 15 2129 2140 2HOY 16954186 Inter-subunit signaling in GSAM 2006-07-17 2006-08-22 Stetefeld, J.,Jenny, M.,Burkhard, P. Intersubunit signaling in glutamate-1-semialdehyde-aminomutase. Proc.Natl.Acad.Sci.Usa 2006 103 13688 13693 2HOZ 16954186 Inter-subunit signaling in GSAM 2006-07-17 2006-08-22 Stetefeld, J.,Jenny, M.,Burkhard, P. Intersubunit signaling in glutamate-1-semialdehyde-aminomutase. Proc.Natl.Acad.Sci.Usa 2006 103 13688 13693 2HP1 16954186 Inter-subunit signaling in GSAM 2006-07-17 2006-08-22 Stetefeld, J.,Jenny, M.,Burkhard, P. Intersubunit signaling in glutamate-1-semialdehyde-aminomutase. Proc.Natl.Acad.Sci.Usa 2006 103 13688 13693 2AEZ 17335500 Crystal structure of fructan 1-exohydrolase IIa (E201Q) from Cichorium intybus in complex with 1-kestose 2005-07-25 2006-08-29 Verhaest, M.,Lammens, W.,Le Roy, K.,De Ranter, C.J.,Van Laere, A.,Rabijns, A.,Van den Ende, W. Insights into the fine architecture of the active site of chicory fructan 1-exohydrolase: 1-kestose as substrate vs sucrose as inhibitor. New Phytol 2007 174 90 100 2GKM 16846220 Crystal structure of Mycobacterium tuberculosis trHbN TyrB10Phe mutant 2006-04-03 2006-09-19 Ouellet, Y.,Milani, M.,Couture, M.,Bolognesi, M.,Guertin, M. Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues Biochemistry 2006 45 8770 8781 2GDU 16990265 E232Q mutant of sucrose phosphorylase from BIFIDOBACTERIUM ADOLESCENTIS in complex with sucrose 2006-03-17 2006-09-26 Mirza, O.,Skov, L.K.,Sprogoe, D.,van den Broek, L.A.M.,Beldman, G.,Kastrup, J.S.,Gajhede, M. Structural Rearrangements of Sucrose Phosphorylase from Bifidobacterium adolescentis during Sucrose Conversion J.Biol.Chem. 2006 281 35576 35584 2GDV Sucrose phosphorylase from BIFIDOBACTERIUM ADOLESCENTIS reacted with sucrose 2006-03-17 2006-09-26 Mirza, O.,Skov, L.K.,Sprogoe, D.,Van den Broek, L.A.M.,Voragen, A.G.J.,Katsrup, J.S.,Gajhede, M. Structural rearrangements of Sucrose Phosphorylase from Bifidobacterium adolescentis during sucrose conversion To be Published 0 0 0 0 2IAV 15966726 Crystal structure of squid ganglion DFPase H287A mutant 2006-09-08 2006-09-26 Katsemi, V.,Luecke, C.,Koepke, J.,Loehr, F.,Maurer, S.,Fritzsch, G.,Rueterjans, H. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme Biochemistry 2005 44 9022 9033 2IAW 15966726 Crystal structure of squid ganglion DFPase N175D mutant 2006-09-08 2006-09-26 Katsemi, V.,Luecke, C.,Koepke, J.,Loehr, F.,Maurer, S.,Fritzsch, G.,Rueterjans, H. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme Biochemistry 2005 44 9022 9033 2IAX 15966726 Crystal structure of squid ganglion DFPase D232S mutant 2006-09-08 2006-09-26 Katsemi, V.,Luecke, C.,Koepke, J.,Loehr, F.,Maurer, S.,Fritzsch, G.,Rueterjans, H. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme Biochemistry 2005 44 9022 9033 2A27 Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 8 monomers in the asymmetric unit 2005-06-22 2006-10-10 Kursula, P.,Lehmann, F.,Shani, G.,Kimchi, A.,Wilmanns, M. Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 8 monomers in the asymmetric unit To be Published 0 0 0 0 2H24 16982608 Crystal structure of human IL-10 2006-05-18 2006-10-17 Yoon, S.I.,Logsdon, N.J.,Sheikh, F.,Donnelly, R.P.,Walter, M.R. Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex. J.Biol.Chem. 2006 281 35088 35096 1Z9X Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 3 monomers in the asymmetric unit 2005-04-05 2006-10-24 Kursula, P.,Lehmann, F.,Shani, G.,Kimchi, A.,Wilmanns, M. A structural insight into the double-locking mechanism of the human death-associated DRP-1 kinase To be Published 0 0 0 0 2F2W 17330285 alpha-spectrin SH3 domain R21A mutant 2005-11-18 2006-10-31 Casares, S.,Lopez-Mayorga, O.,Vega, M.C.,Camara-Artigas, A.,Conejero-Lara, F. Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain Proteins 2007 67 531 547 2F2X 17330285 alpha-spectrin SH3 domain R21G mutant 2005-11-18 2006-10-31 Casares, S.,Lopez-Mayorga, O.,Vega, M.C.,Camara-Artigas, A.,Conejero-Lara, F. Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain Proteins 2007 67 531 547 2D4L 17169987 Crystal structure of truncated in C-terminal M-PMV dUTPase 2005-10-20 2006-11-07 Nemeth-Pongracz, V.,Barabas, O.,Fuxreiter, M.,Simon, I.,Pichova, I.,Rumlova, M.,Zabranska, H.,Svergun, D.,Petoukhov, M.,Harmat, V.,Klement, E.,Hunyadi-Gulyas, E.,Medzihradszky, K.F.,Konya, E.,Vertessy, B.G. Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins. Nucleic Acids Res. 2007 35 495 505 2NLO 18566515 Crystal Structure of the Quinate Dehydrogenase from Corynebacterium glutamicum 2006-10-20 2006-11-14 Schoepe, J.,Niefind, K.,Schomburg, D. 1.6 A structure of an NAD(+)-dependent quinate dehydrogenase from Corynebacterium glutamicum Acta Crystallogr.,Sect.D 2008 64 803 809 2FLH 16998071 Crystal structure of cytokinin-specific binding protein from mung bean in complex with cytokinin 2006-01-06 2006-11-21 Pasternak, O.,Bujacz, G.D.,Fujimoto, Y.,Hashimoto, Y.,Jelen, F.,Otlewski, J.,Sikorski, M.M.,Jaskolski, M. Crystal Structure of Vigna radiata Cytokinin-Specific Binding Protein in Complex with Zeatin. Plant Cell 2006 18 2622 2634 2C94 16984393 LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) 1,1 difluoropentane-1- PHOSPHATE 2005-12-09 2006-12-13 Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J. 2006 273 4790 0 2C97 16984393 LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 4-(6- chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)butyl phosphate 2005-12-09 2006-12-13 Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J. 2006 273 4790 0 2CEI 17070541 Recombinant human H ferritin, K86Q mutant, soaked with Zn 2006-02-07 2006-12-13 Toussaint, L.,Bertrand, L.,Hue, L.,Crichton, R.R.,Declercq, J.P. High-Resolution X-Ray Structures of Human Apoferritin H-Chain Mutants Correlated with Their Activity and Metal-Binding Sites. J.Mol.Biol. 2007 365 440 0 2CHI 17070541 Recombinant human H ferritin, K86Q and E27D mutant 2006-03-15 2006-12-13 Toussaint, L.,Bertrand, L.,Hue, L.,Crichton, R.R.,Declercq, J.P. High-Resolution X-Ray Structures of Human Apoferritin H-Chain Mutants Correlated with Their Activity and Metal-Binding Sites. J.Mol.Biol. 2007 365 440 0 2HW8 17139090 Structure of ribosomal protein L1-mRNA complex at 2.1 resolution. 2006-08-01 2006-12-19 Tishchenko, S.,Nikonova, E.,Nikulin, A.,Nevskaya, N.,Volchkov, S.,Piendl, W.,Garber, M.,Nikonov, S. Structure of the ribosomal protein L1-mRNA complex at 2.1 A resolution: common features of crystal packing of L1-RNA complexes. ACTA CRYSTALLOGR.,SECT.D 2006 62 1545 1554 2HYY 17164530 Human Abl kinase domain in complex with imatinib (STI571, Glivec) 2006-08-08 2007-01-16 Cowan-Jacob, S.W.,Fendrich, G.,Floersheimer, A.,Furet, P.,Liebetanz, J.,Rummel, G.,Rheinberger, P.,Centeleghe, M.,Fabbro, D.,Manley, P.W. Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. ACTA CRYSTALLOGR.,SECT.D 2007 63 80 93 2IPI 17242508 Crystal Structure of Aclacinomycin Oxidoreductase 2006-10-12 2007-01-23 Sultana, A.,Alexeev, I.,Kursula, I.,Mantsala, P.,Niemi, J.,Schneider, G. Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning. Acta Crystallogr.,Sect.D 2007 63 149 159 2OB1 17372358 ppm1 with 1,8-ANS 2006-12-18 2007-01-30 Groves, M.R.,Muller, I.B.,Kreplin, X.,Muller-Dieckmann, J. A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye. Acta Crystallogr.,Sect.D 2007 63 526 535 2FSS 17525463 Candida boidinii formate dehydrogenase (FDH) K47E mutant 2006-01-23 2007-02-13 Schirwitz, K.,Schmidt, A.,Lamzin, V.S. High-resolution structures of formate dehydrogenase from Candida boidinii. Protein Sci. 2007 16 1146 1156 2JHF 17429946 Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase 2007-02-22 2007-04-24 Meijers, R.,Adolph, H.W.,Dauter, Z.,Wilson, K.S.,Lamzin, V.S.,Cedergren-Zeppezauer, E.S. Structural Evidence for a Ligand Coordination Switch in Liver Alcohol Dehydrogenase Biochemistry 2007 46 5446 0 2CHC Structure of Rv3472(D26N), a function unknown protein from Mycobacterium tuberculosis 2006-03-13 2007-05-01 Ma, Q.,Wilmanns, M. Structure of Rv3472(D26N), a Function Unknown Protein from Mycobacterium Tuberculosis To be Published 0 0 0 0 2JFB 17446177 3D Structure of Lumazine Synthase from Candida albicans 2007-01-30 2007-05-01 Morgunova, E.,Saller, S.,Haase, I.,Cushman, M.,Bacher, A.,Fischer, M.,Ladenstein, R. Lumazine Synthase from Candida Albicans as an Anti- Fungal Target Enzyme: Structural and Biochemical Basis for Drug Design. J.Biol.Chem. 2007 282 17231 0 2OFC 17391699 The crystal structure of Sclerotium rolfsii lectin 2007-01-03 2007-05-01 Leonidas, D.D.,Swamy, B.M.,Hatzopoulos, G.N.,Gonchigar, S.J.,Chachadi, V.B.,Inamdar, S.R.,Zographos, S.E.,Oikonomakos, N.G. Structural Basis for the Carbohydrate Recognition of the Sclerotium rolfsii Lectin J.Mol.Biol. 2007 368 1145 1161 2J8C 17570397 X-ray high resolution structure of the photosynthetic reaction center from Rb. sphaeroides at pH 8 in the neutral state 2006-10-24 2007-07-03 Koepke, J.,Krammer, E.M.,Klingen, A.R.,Sebban, P.,Ullmann, G.M.,Fritzsch, G. Ph Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter Sphaeroides in the Neutral and Charge Separated States. J.Mol.Biol. 2007 371 396 0 2J8D 17570397 X-ray high resolution structure of the photosynthetic reaction center from Rb. sphaeroides at pH 8 in the charge-separated state 2006-10-24 2007-07-03 Koepke, J.,Krammer, E.M.,Klingen, A.R.,Sebban, P.,Ullmann, G.M.,Fritzsch, G. Ph Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter Sphaeroides in the Neutral and Charge Separated States. J.Mol.Biol. 2007 371 396 0 2UX3 17570397 X-ray high resolution structure of the photosynthetic reaction center from Rb. sphaeroides at pH 9 in the neutral state 2007-03-26 2007-07-03 Koepke, J.,Krammer, E.M.,Klingen, A.R.,Sebban, P.,Ullmann, G.M.,Fritzsch, G. Ph Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter Sphaeroides in the Neutral and Charge Separated States. J.Mol.Biol. 2007 371 396 0 2UX5 17570397 X-ray high resolution structure of the photosynthetic reaction center from Rb. sphaeroides at pH 9 in the charge-separated state 2007-03-26 2007-07-03 Koepke, J.,Krammer, E.M.,Klingen, A.R.,Sebban, P.,Ullmann, G.M.,Fritzsch, G. Ph Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter Sphaeroides in the Neutral and Charge Separated States. J.Mol.Biol. 2007 371 396 0 2HRM 17932923 Crystal structure of dUTPase complexed with substrate analogue methylene-dUTP 2006-07-20 2007-07-31 Kovari, J.,Barabas, O.,Varga, B.,Bekesi, A.,Tolgyesi, F.,Fidy, J.,Nagy, J.,Vertessy, B.G. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. Proteins 2008 71 308 319 2HZH Crystal structure of laccase from Coriolus zonatus at 2.6 A resolution 2006-08-09 2007-08-14 Lyashenko, A.V.,Zhukhlistova, N.E.,Gabdoulkhakov, A.G.,Zhukova, Y.N.,Voelter, W.,Zaitsev, V.N.,Bento, I.,Stepanova, E.V.,Kachalova, G.S.,Koroleva, O.V.,Betzel, C.,Lindley, P.F.,Mikhailov, A.M.,Tishkov, V.I.,Morgunova, E.Y. Crystal structure of laccase from Coriolus zonatus at 2.6 A resolution To be published 0 0 0 0 2QA2 17669423 Crystal structure of CabE, an aromatic hydroxylase from angucycline biosynthesis, determined to 2.7 A resolution 2007-06-14 2007-08-14 Koskiniemi, H.,Metsa-Ketela, M.,Dobritzsch, D.,Kallio, P.,Korhonen, H.,Mantsala, P.,Schneider, G.,Niemi, J. Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis J.Mol.Biol. 2007 372 633 648 2IXT 18655058 SPHERICASE 2006-07-11 2007-08-21 Almog, O.,Gonzalez, A.,Godin, N.,De Leeuw, M.,Mekel, M.J.,Klein, D.,Braun, S.,Shoham, G.,Walter, R.L. The Crystal Structures of the Psychrophilic Subtilisin S41 and the Mesophilic Subtilisin Sph Reveal the Same Calcium-Loaded State. Proteins 2009 74 489 0 2HRG Crystal Structure of Blue Laccase from Trametes trogii complexed with p-methylbenzoate 2006-07-20 2007-09-11 Matera, I.,Gullotto, A.,Tilli, S.,Ferraroni, M.,Scozzafava, A.,Briganti, F. Crystal structure of the blue multicopper oxidase from the white-rot fungus Trametes trogii complexed with p-toluate Inorg.Chim.Acta. 2008 361 4129 4137 2V8T Crystal structure of Mn catalase from Thermus Thermophilus complexed with chloride 2007-08-14 2007-09-11 Antonyuk, S.V.,Melik-Adamyan, W.R.,Popov, A.N.,Lamsin, V.S.,Hempstead, P.D.,Harrison, P.M.,Artymyuk, P.J.,Barynin, V.V. Three-Dimentional Structure of the Enzyme Dimanganese Catalase from Thermus Thermophilus at 1 Angstrom Resolution Crystallogr.Rep.(Transl. Krist 2000 45 105 0 2V8U Atomic resolution structure of Mn catalase from Thermus Thermophilus 2007-08-14 2007-09-25 Antonyuk, S.V.,Melik-Adamyan, W.R.,Popov, A.N.,Lamsin, V.S.,Hempstead, P.D.,Harrison, P.M.,Artymyuk, P.J.,Barynin, V.V. Three-Dimentional Structure of the Enzyme Dimanganese Catalase from Thermus Thermophilus at 1 Angstrom Resolution Crystallogr.Rep.(Transl. Krist 2000 45 105 0 2J7V 19100272 Structure of PBP-A 2006-10-17 2007-11-06 Urbach, C.,Evrard, C.,Pudzaitis, V.,Fastrez, J.,Soumillion, P.,Declercq, J.P. Structure of Pbp-A from Thermosynechococcus Elongatus, a Penicillin-Binding Protein Closely Related to Class a Beta-Lactamases. J.Mol.Biol. 2009 386 109 0 2J8W 18295896 The crystal structure of cytochrome c' from Rubrivivax gelatinosus at 1.3 A Resolution and pH 8.0 2006-10-30 2007-11-06 Benini, S.,Rypniewski, W.R.,Wilson, K.S.,Ciurli, S. High resolution crystal structure of Rubrivivax gelatinosus cytochrome c'. J. Inorg. Biochem. 2008 102 1322 1328 2RHG Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine 2007-10-09 2007-11-20 Kulik, V.,Barends, T.,Schlichting, I. Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine To be Published 0 0 0 0 2J9B 18295896 THE CRYSTAL STRUCTURE OF CYTOCHROME C' FROM RUBRIVIVAX GELATINOSUS AT 1.5 A RESOLUTION AND PH 6.3 2006-11-06 2007-12-04 Benini, S.,Rypniewski, W.R.,Wilson, K.S.,Ciurli, S. High resolution crystal structure of Rubrivivax gelatinosus cytochrome c'. J. Inorg. Biochem. 2008 102 1322 1328 2J9O 19100272 Structure of PBP-A, L158E mutant 2006-11-14 2007-12-11 Urbach, C.,Evrard, C.,Pudzaitis, V.,Fastrez, J.,Soumillion, P.,Declercq, J.P. Structure of Pbp-A from Thermosynechococcus Elongatus, a Penicillin-Binding Protein Closely Related to Class a Beta-Lactamases. J.Mol.Biol. 2009 386 109 0 2R8O 17914867 Transketolase from E. coli in complex with substrate D-xylulose-5-phosphate 2007-09-11 2007-12-11 Asztalos, P.,Parthier, C.,Golbik, R.,Kleinschmidt, M.,Hubner, G.,Weiss, M.S.,Friedemann, R.,Wille, G.,Tittmann, K. Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate. Biochemistry 2007 46 12037 12052 2R8P 17914867 Transketolase from E. coli in complex with substrate D-fructose-6-phosphate 2007-09-11 2007-12-11 Asztalos, P.,Parthier, C.,Golbik, R.,Kleinschmidt, M.,Hubner, G.,Weiss, M.S.,Friedemann, R.,Wille, G.,Tittmann, K. Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate. Biochemistry 2007 46 12037 12052 2V17 18061582 Structure of the complex of antibody MN423 with a fragment of tau protein 2007-05-22 2007-12-25 Sevcik, J.,Skrabana, R.,Dvorsky, R.,Csokova, N.,Iqbal, K.,Novak, M. X-Ray Structure of the Phf Core C-Terminus: Insight Into the Folding of the Intrinsically Disordered Protein Tau in Alzheimer'S Disease. FEBS Lett. 2007 581 5872 0 3B5J 18155559 Crystal Structures of the S504A Mutant of an Isolated ABC-ATPase in Complex with TNP-ADP 2007-10-26 2008-01-15 Oswald, C.,Jenewein, S.,Smits, S.H.J.,Holland, I.B.,Schmitt, L. Water-mediated protein-fluorophore interactions modulate the affinity of an ABC-ATPase/TNP-ADP complex J.Struct.Biol. 2008 162 85 93 3BQC 18242640 High pH-value crystal structure of emodin in complex with the catalytic subunit of protein kinase CK2 2007-12-20 2008-01-15 Raaf, J.,Klopffleisch, K.,Issinger, O.-G.,Niefind, K. The Catalytic Subunit of Human Protein Kinase CK2 Structurally Deviates from Its Maize Homologue in Complex with the Nucleotide Competitive Inhibitor Emodin J.Mol.Biol. 2008 377 1 8 2JBF 19100272 Structure of PBP-A, L158E mutant. Acyl-enzyme complex with penicillin- G. 2006-12-06 2008-02-05 Urbach, C.,Evrard, C.,Pudzaitis, V.,Fastrez, J.,Soumillion, P.,Declercq, J.-P. Structure of Pbp-A from Thermosynechococcus Elongatus, a Penicillin-Binding Protein Closely Related to Class a Beta-Lactamases. J.Mol.Biol. 2009 386 109 0 2P8D 18160414 The Structure of the Dickerson Sequence with an Incorporated CeNA Residue 2007-03-22 2008-02-05 Robeyns, K.,Herdewijn, P.,Van Meervelt, L. Influence of the incorporation of a cyclohexenyl nucleic acid (CeNA) residue onto the sequence d(CGCGAATTCGCG). Nucleic Acids Res. 2008 36 1407 1414 2V2D 18219118 The A178L mutation in the C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (TIM) induces a more closed conformation of this hinge region in dimeric and monomeric TIM 2007-06-05 2008-02-19 Alahuhta, M.,Casteleijn, M.G.,Neubauer, P.,Wierenga, R.K. Structural Studies Show that the A178L Mutation in the C-Terminal Hinge of the Catalytic Loop-6 of Triosephosphate Isomerase (Tim) Induces a Closed- Like Conformation in Dimeric and Monomeric Tim. Acta Crystallogr.,Sect.D 2008 64 178 0 3BNF 18201106 W. succinogenes NrfA Sulfite Complex 2007-12-14 2008-02-26 Lukat, P.,Rudolf, M.,Stach, P.,Messerschmidt, A.,Kroneck, P.M.H.,Simon, J.,Einsle, O. Binding and Reduction of Sulfite by Cytochrome c Nitrite Reductase Biochemistry 2008 47 2080 2086 2VBK 18462681 NATIVE TAILSPIKE PROTEIN OF BACTERIOPHAGE SF6 2007-09-14 2008-04-01 Muller, J.J.,Barbirz, S.,Heinle, K.,Freiberg, A.,Seckler, R.,Heinemann, U. An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6. Structure 2008 16 766 775 2V32 18359859 Crystal Structure of the C45S mutant of the Peroxiredoxin 6 of Arenicola Marina. Monoclinic form 2 2007-06-11 2008-04-08 Smeets, A.,Loumaye, E.,Clippe, A.,Rees, J.F.,Knoops, B.,Declercq, J.P. The Crystal Structure of the C45S Mutant of Annelid Arenicola Marina Peroxiredoxin 6 Supports its Assignment to the Mechanistically Typical 2-Cys Subfamily without Any Formation of Toroid-Shaped Decamers. Protein Sci. 2008 17 700 0 2PHD Crystal Structure Determination of a Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans 2007-04-11 2008-04-22 Ferraroni, M.,Matera, I.,Briganti, F.,Stolz, A.,Burger, S. Crystal Structure Determination of a Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans To be Published 0 0 0 0 2PYA 17712580 Ultra-high resolution structure of P. abyssi rubredoxin W4L/R5S/A44S 2007-05-16 2008-04-29 Bonisch, H.,Schmidt, C.L.,Bianco, P.,Ladenstein, R. Ultrahigh-resolution study on Pyrococcus abyssi rubredoxin: II. Introduction of an O-H...Sgamma-Fe hydrogen bond increased the reduction potential by 65 mV. J.Biol.Inorg.Chem. 2007 12 1163 1171 3C6X 18524775 HNL from Hevea brasiliensis to atomic resolution 2008-02-06 2008-06-03 Schmidt, A.,Gruber, K.,Kratky, C.,Lamzin, V.S. Atomic resolution crystal structures and quantum chemistry meet to reveal subtleties of hydroxynitrile lyase catalysis J.Biol.Chem. 2008 283 21827 21836 3C6Z 18524775 HNL from Hevea brasiliensis to atomic resolution 2008-02-06 2008-06-03 Schmidt, A.,Gruber, K.,Kratky, C.,Lamzin, V.S. Atomic resolution crystal structures and quantum chemistry meet to reveal subtleties of hydroxynitrile lyase catalysis J.Biol.Chem. 2008 283 21827 21836 3C8P 18703848 X-ray structure of Viscotoxin A1 from Viscum album L. 2008-02-13 2008-06-17 Pal, A.,Debreczeni, J.E.,Sevvana, M.,Gruene, T.,Kahle, B.,Zeeck, A.,Sheldrick, G.M. 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Binding of sulfite by the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase To be Published 0 0 0 0 3C75 18512962 Paracoccus versutus methylamine dehydrogenase in complex with amicyanin 2008-02-06 2008-12-30 Cavalieri, C.,Biermann, N.,Vlasie, M.D.,Einsle, O.,Merli, A.,Ferrari, D.,Rossi, G.L.,Ubbink, M. Structural comparison of crystal and solution states of the 138 kDa complex of methylamine dehydrogenase and amicyanin from Paracoccus versutus. Biochemistry 2008 47 6560 6570 3BZ0 21696158 Lactobacillus Casei Thymidylate Synthase Ternary Complex with DUMP and the Phtalimidic Derivative C00 2008-01-17 2009-01-20 Mangani, S.,Cancian, L.,Leone, R.,Pozzi, C.,Lazzari, S.,Luciani, R.,Ferrari, S.,Costi, M.P. Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening J.Med.Chem. 2011 54 5454 5467 3F1J 19237566 Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals RNA binding properties 2008-10-28 2009-02-03 Neumann, P.,Lieber, D.,Meyer, S.,Dautel, P.,Kerth, A.,Kraus, I.,Garten, W.,Stubbs, M.T. Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals ssRNA binding properties Proc.Natl.Acad.Sci.USA 2009 106 3710 3715 3FZ7 Crystal structure of apo glutamate decarboxylase beta from Escherichia coli 2009-01-23 2009-02-03 Malashkevich, V.N.,De Biase, D.,Bossa, F. Crystal structure of apo glutamate decarboxylase beta from Escherichia coli To be Published 0 0 0 0 3FZ8 Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP 2009-01-23 2009-02-03 Malashkevich, V.N.,De Biase, D.,Bossa, F. 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Proteins 2009 74 489 496 2W16 19504741 Structures of FpvA bound to heterologous pyoverdines 2008-10-14 2009-05-12 Greenwald, J.,Nader, M.,Celia, H.,Gruffaz, C.,Geoffroy, V.,Meyer, J.M.,Schalk, I.J.,Pattus, F. Fpva Bound to Non-Cognate Pyoverdines: Molecular Basis of Siderophore Recognition by an Iron Transporter. Mol.Microbiol. 2009 72 1246 0 2W6T 19504741 Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(DSM50106)-Fe complex 2008-12-19 2009-05-12 Greenwald, J.,Nader, M.,Celia, H.,Gruffaz, C.,Geoffroy, V.,Meyer, J.M.,Schalk, I.J.,Pattus, F. Fpva Bound to Non-Cognate Pyoverdines: Molecular Basis of Siderophore Recognition by an Iron Transporter. Mol.Microbiol. 2009 72 1246 0 2W6U 19504741 Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(G173)-Fe complex 2008-12-19 2009-05-12 Greenwald, J.,Nader, M.,Celia, H.,Gruffaz, C.,Geoffroy, V.,Meyer, J.M.,Schalk, I.J.,Pattus, F. 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Proteins 2010 78 1878 0 3HPW 19647513 CcdB dimer in complex with one C-terminal CcdA domain 2009-06-05 2009-08-11 De Jonge, N.,Garcia-Pino, A.,Buts, L.,Haesaerts, S.,Charlier, D.,Zangger, K.,Wyns, L.,De Greve, H.,Loris, R. Rejuvenation of CcdB-Poisoned Gyrase by an Intrinsically Disordered Protein Domain. Mol.Cell 2009 35 154 163 3FU8 19563811 Melanocarpus albomyces laccase crystal soaked (10 sec) with 2,6-dimethoxyphenol 2009-01-14 2009-09-22 Kallio, J.P.,Auer, S.,Janis, J.,Andberg, M.,Kruus, K.,Rouvinen, J.,Koivula, A.,Hakulinen, N. Structure-Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol. 2009 392 895 909 3G2U 20015111 VHS Domain of human GGA1 complexed with Sotilin C-terminal Peptide 2009-02-01 2009-12-15 Cramer, J.F.,Gustafsen, C.,Behrens, M.A.,Oliveira, C.L.P.,Pedersen, J.S.,Madsen, P.,Petersen, C.M.,Thirup, S.S. 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Angew.Chem.Int.Ed.Engl. 2022 61 0 0 7QVW R396W mutant of the vanadium-dependent bromoperoxidase from Corallina pilulifera 2022-01-23 2023-02-01 Isupov, M.N.,Mitchell, D.,Littelchild, J.A.,Garcia-Rodriguez, E. R396W mutant of the vanadium-dependent bromoperoxidase from Corallina pilulifera To Be Published 0 0 0 0