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Embo J. 2007 26 623 0 2C8T 17242518 The 3.0 A Resolution Structure of Caseinolytic Clp Protease 1 from Mycobacterium tuberculosis 2005-12-07 2007-02-06 Ingvarsson, H.,Mate, M.J.,Hogbom, M.,Portnoi, D.,Benaroudj, N.,Alzari, P.M.,Ortiz-Lombardia, M.,Unge, T. Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D 2007 63 249 0 2HCN 17287213 Crystal structure of RNA dependent RNA polymerase domain from west nile virus 2006-06-17 2007-02-06 Malet, H.,Egloff, M.P.,Selisko, B.,Butcher, R.E.,Wright, P.J.,Roberts, M.,Gruez, A.,Sulzenbacher, G.,Vonrhein, C.,Bricogne, G.,Mackenzie, J.M.,Khromykh, A.A.,Davidson, A.D.,Canard, B. 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J.Med.Chem. 2006 49 1828 0 2OK7 17258767 Ferredoxin-NADP+ reductase from Plasmodium falciparum with 2'P-AMP 2007-01-16 2007-02-13 Milani, M.,Balconi, E.,Aliverti, A.,Mastrangelo, E.,Seeber, F.,Bolognesi, M.,Zanetti, G. Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis. J.Mol.Biol. 2007 367 501 513 2J59 17347647 Crystal structure of the ARF1:ARHGAP21-ArfBD complex 2006-09-13 2007-02-20 Menetrey, J.,Perderiset, M.,Cicolari, J.,Dubois, T.,El Khatib, N.,El Khadali, F.,Franco, M.,Chavrier, P.,Houdusse, A. Structural Basis for Arf1-Mediated Recruitment of Arhgap21 to Golgi Membranes. Embo J. 2007 26 1953 0 2JAH 17279617 Biochemical and structural analysis of the Clavulanic acid dehydeogenase (CAD) from Streptomyces clavuligerus 2006-11-28 2007-02-20 Mackenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. 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To be Published 0 0 0 0 2O4I 17355961 Structure of TREX1 in complex with DNA 2006-12-04 2007-03-13 Brucet, M.,Querol-Audi, J.,Serra, M.,Ramirez-Espain, X.,Bertlik, K.,Ruiz, L.,Lloberas, J.,Macias, M.J.,Fita, I.,Celada, A. Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains. J.Biol.Chem. 2007 282 14547 14557 2OHN 17315856 X-ray crystal structure of beta secretase complexed with 4-(4-fluorobenzyl)piperidine 2007-01-10 2007-03-13 Murray, C.W.,Callaghan, O.,Chessari, G.,Cleasby, A.,Congreve, M.,Frederickson, M.,Hartshorn, M.J.,McMenamin, R.,Patel, S.,Wallis, N. Application of fragment screening by X-ray crystallography to beta-Secretase. J.Med.Chem. 2007 50 1116 1123 2OHQ 17315857 X-ray crystal structure of beta secretase complexed with compound 4 2007-01-10 2007-03-13 Congreve, M.,Aharony, D.,Albert, J.,Callaghan, O.,Campbell, J.,Carr, R.A.,Chessari, G.,Cowan, S.,Edwards, P.D.,Frederickson, M.,McMenamin, R.,Murray, C.W.,Patel, S.,Wallis, N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem. 2007 50 1124 1132 2OHR 17315857 X-ray crystal structure of beta secretase complexed with compound 6a 2007-01-10 2007-03-13 Congreve, M.,Aharony, D.,Albert, J.,Callaghan, O.,Campbell, J.,Carr, R.A.,Chessari, G.,Cowan, S.,Edwards, P.D.,Frederickson, M.,McMenamin, R.,Murray, C.W.,Patel, S.,Wallis, N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem. 2007 50 1124 1132 2OHS 17315857 X-ray crystal structure of beta secretase complexed with compound 6b 2007-01-10 2007-03-13 Congreve, M.,Aharony, D.,Albert, J.,Callaghan, O.,Campbell, J.,Carr, R.A.,Chessari, G.,Cowan, S.,Edwards, P.D.,Frederickson, M.,McMenamin, R.,Murray, C.W.,Patel, S.,Wallis, N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem. 2007 50 1124 1132 2OHT 17315857 X-ray crystal structure of beta secretase complexed with compound 7 2007-01-10 2007-03-13 Congreve, M.,Aharony, D.,Albert, J.,Callaghan, O.,Campbell, J.,Carr, R.A.,Chessari, G.,Cowan, S.,Edwards, P.D.,Frederickson, M.,McMenamin, R.,Murray, C.W.,Patel, S.,Wallis, N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. 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J.Med.Chem. 2007 50 2301 2309 2IBT 17455934 Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position 2006-09-12 2007-05-29 Lenz, T.,Bonnist, E.Y.M.,Pljevaljcic, G.,Neely, R.K.,Dryden, D.T.F.,Scheidig, A.J.,Jones, A.C.,Weinhold, E. 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc. 2007 129 6240 6248 2CLE 17559195 Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6) - lowF6 complex 2006-04-27 2007-06-12 Ngo, H.,Harris, R.,Kimmich, N.,Casino, P.,Niks, D.,Blumenstein, L.,Barends, T.R.,Kulik, V.,Weyand, M.,Schlichting, I.,Dunn, M.F. Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex. 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J.Mol.Biol. 2007 373 633 0 2V5W 17721440 Crystal structure of HDAC8-substrate complex 2007-07-10 2007-09-04 Vannini, A.,Volpari, C.,Gallinari, P.,Jones, P.,Mattu, M.,Carfi, A.,Defrancesco, R.,Steinkuhler, C.,Di Marco, S. Substrate Binding to Histone Deacetylases as Revealed by Crystal Structure of Hdac8-Substrate Complex Embo Rep. 2007 8 879 0 2V5X 17721440 Crystal structure of HDAC8-inhibitor complex 2007-07-10 2007-09-04 Vannini, A.,Volpari, C.,Gallinari, P.,Jones, P.,Mattu, M.,Carfi, A.,Defrancesco, R.,Steinkuhler, C.,Di Marco, S. Substrate Binding to Histone Deacetylases as Revealed by Crystal Structure of Hdac8-Substrate Complex Embo Rep. 2007 8 879 0 2NSP 17717531 Crystal structure of pectin methylesterase D178A mutant in complex with hexasaccharide I 2006-11-06 2007-09-18 Fries, M.,Ihrig, J.,Brocklehurst, K.,Shevchik, V.E.,Pickersgill, R.W. Molecular basis of the activity of the phytopathogen pectin methylesterase. 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The crystal structure of the all cysteinyl coordinated D14C variant of [4Fe-4S] Pyrococcus furiosus ferredoxin To be Published 0 0 0 0 2V8H 17916556 Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri in complex with its substrate N-carbamyl-beta- alanine 2007-08-08 2007-10-02 Lundgren, S.,Andersen, B.,Piskur, J.,Dobritzsch, D. Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements. J.Biol.Chem. 2007 282 36037 0 2JD3 17898804 ParR from plasmid pB171 2007-01-04 2007-10-09 Moller-Jensen, J.,Ringgaard, S.,Mercogliano, C.P.,Gerdes, K.,Lowe, J. Structural Analysis of the Parr/Parc Plasmid Partition Complex. Embo J. 2007 26 4413 0 2JJ4 17959776 The complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC7942 2007-07-04 2007-10-16 Llacer, J.L.,Contreras, A.,Forchhammer, K.,Marco-Marin, C.,Gil-Ortiz, F.,Maldonado, R.,Fita, I.,Rubio, V. The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine Proc.Natl.Acad.Sci.USA 2007 104 17644 0 2V5H 17959776 Controlling the storage of nitrogen as arginine: the complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC 7942 2007-07-04 2007-10-16 Llacer, J.L.,Contreras, A.,Forchhammer, K.,Marco-Marin, C.,Gil-Ortiz, F.,Maldonado, R.,Fita, I.,Rubio, V. The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine. Proc.Natl.Acad.Sci.USA 2007 104 17644 0 2JIJ 17940281 Crystal structure of the apo form of Chlamydomonas reinhardtii prolyl- 4 hydroxylase type I 2007-06-28 2007-10-30 Koski, M.K.,Hieta, R.,Bollner, C.,Kivirikko, K.I.,Myllyharju, J.,Wierenga, R.K. The Active Site of an Algal Prolyl 4-Hydroxylase Has a Large Structural Plasticity. J.Biol.Chem. 2007 282 37112 0 2PYO 17957772 Drosophila nucleosome core 2007-05-16 2007-11-06 Clapier, C.R.,Chakravarthy, S.,Petosa, C.,Fernandez-Tornero, C.,Luger, K.,Muller, C.W. Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins 2007 71 1 7 2QRW 17887774 Crystal structure of Mycobacterium tuberculosis trHbO WG8F mutant 2007-07-30 2007-11-06 Ouellet, H.,Milani, M.,LaBarre, M.,Bolognesi, M.,Couture, M.,Guertin, M. The Roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis Truncated Hemoglobin O in Ligand Binding and on the Heme Distal Site Architecture Biochemistry 2007 46 11440 11450 2RH9 Tryptophan synthase complexed with IGP, internal aldimine, pH 9.0 2007-10-08 2007-11-06 Kulik, V.,Barends, T.R.M.,Schlichting, I. Tryptophan synthase complexed with IGP, internal aldimine, pH 9.0. To be Published 0 0 0 0 2IH4 Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing pyrrolo-dC at the target base partner position 2006-09-25 2007-11-13 Lenz, T.,Scheidig, A.J.,Weinhold, E. Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI To be Published 0 0 0 0 2IH5 Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target base partner position 2006-09-25 2007-11-13 Lenz, T.,Scheidig, A.J.,Weinhold, E. Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI To be Published 0 0 0 0 2NP6 Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target position 2006-10-26 2007-11-13 Lenz, T.,Scheidig, A.J.,Weinhold, E. Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI To be Published 0 0 0 0 2NP7 Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target position and pyrrolo-dC at the target base partner position 2006-10-26 2007-11-13 Lenz, T.,Scheidig, A.J.,Weinhold, E. Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI To be Published 0 0 0 0 2QTL 17892308 Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase 2007-08-02 2007-11-13 Wolthers, K.R.,Lou, X.,Toogood, H.S.,Leys, D.,Scrutton, N.S. Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry 2007 46 11833 11844 2QTZ 17892308 Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase 2007-08-02 2007-11-13 Wolthers, K.R.,Lou, X.,Toogood, H.S.,Leys, D.,Scrutton, N.S. Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry 2007 46 11833 11844 2VA7 17985862 X-ray crystal structure of beta secretase complexed with compound 27 2007-08-30 2007-11-13 Edwards, P.D.,Albert, J.S.,Sylvester, M.,Aharony, D.,Andisik, D.,Callaghan, O.,Campbell, J.B.,Carr, R.A.,Chessari, G.,Congreve, M.,Frederickson, M.,Folmer, R.H.A.,Geschwindner, S.,Koether, G.,Kolmodin, K.,Krumrine, J.,Mauger, R.C.,Murray, C.W.,Olsson, L.L.,Patel, S.,Spear, N.,Tian, G. Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem. 2007 50 5912 0 2VG0 18597781 Rv1086 citronellyl pyrophosphate complex 2007-11-07 2007-11-13 Wang, W.,Dong, C.,McNeil, M.,Kaur, D.,Mahapatra, S.,Crick, D.C.,Naismith, J.H. The structural basis of chain length control in Rv1086. J. Mol. Biol. 2008 381 129 140 2NZM 20000851 Hexasaccharide I bound to Bacillus subtilis pectate lyase 2006-11-24 2007-11-20 Seyedarabi, A.,To, T.T.,Ali, S.,Hussain, S.,Fries, M.,Madsen, R.,Clausen, M.H.,Teixteira, S.,Brocklehurst, K.,Pickersgill, R.W. Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry 2010 49 539 546 2O04 20000851 Pectate lyase bound to hexasaccharide compound II 2006-11-27 2007-11-20 Seyedarabi, A.,To, T.T.,Ali, S.,Hussain, S.,Fries, M.,Madsen, R.,Clausen, M.H.,Teixteira, S.,Brocklehurst, K.,Pickersgill, R.W. Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry 2010 49 539 546 2O0V 20000851 Pectate lyase bound to hexasaccharide compound III 2006-11-28 2007-11-20 Seyedarabi, A.,To, T.T.,Ali, S.,Hussain, S.,Fries, M.,Madsen, R.,Clausen, M.H.,Teixteira, S.,Brocklehurst, K.,Pickersgill, R.W. Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry 2010 49 539 546 2O0W Pectate lyase bound to hexasaccharide compound IV 2006-11-28 2007-11-20 Seyedarabi, A.,Hussain, S.,Fries, M.,MacDoughall, A.,Cummings, N.,Smith, D.,Worboys, K.,Brocklehurst, K.,Pickersgill, R.W. Structural and thermodynamic insights into the mechanism of pectate lyase To be Published 0 0 0 0 2VGI 11960989 HUMAN ERYTHROCYTE PYRUVATE KINASE: R486W MUTANT 2007-11-13 2007-11-20 Valentini, G.,Chiarelli, L.R.,Fortin, R.,Dolzan, M.,Galizzi, A.,Abraham, D.J.,Wang, C.,Bianchi, P.,Zanella, A.,Mattevi, A. Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia. J.Biol.Chem. 2002 277 23807 0 2VBG 18084069 The complex structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis with 2R-1-hydroxyethyl-deazaThDP 2007-09-12 2007-11-27 Berthold, C.L.,Gocke, D.,Wood, M.D.,Leeper, F.,Pohl, M.,Schneider, G. Crystal Structure of the Branched-Chain Keto Acid Decarboxylase (Kdca) from Lactococcus Lactis Provides Insights Into the Structural Basis for the Chemo- and Enantioselective Carboligation Reaction Acta Crystallogr.,Sect.D 2007 63 1217 0 2VCF 18056997 Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase 2007-09-21 2007-12-04 Metcalfe, C.L.,Macdonald, I.K.,Murphy, E.J.,Brown, K.A.,Raven, E.L.,Moody, P.C.E. The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem. 2008 283 6193 0 2V5O 18046459 STRUCTURE OF HUMAN IGF2R DOMAINS 11-14 2007-07-06 2007-12-11 Brown, J.,Delaine, C.,Zaccheo, O.J.,Siebold, C.,Gilbert, R.J.,Van Boxel, G.,Denley, A.,Wallace, J.C.,Hassan, A.B.,Forbes, B.E.,Jones, E.Y. Structure and Functional Analysis of the Igf-II/Igf2R Interaction Embo J. 2008 27 265 0 2PVS 18702514 Structure of human pancreatic lipase related protein 2 mutant N336Q 2007-05-10 2007-12-18 Eydoux, C.,Spinelli, S.,Davis, T.L.,Walker, J.R.,Seitova, A.,Dhe-Paganon, S.,De Caro, A.,Cambillau, C.,Carriere, F. Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation. Biochemistry 2008 47 9553 9564 2OFA 18323625 Crystal structure of apo AVR4 (R112L,C122S) 2007-01-03 2007-12-25 Hayouka, R.,Eisenberg-Domovich, Y.,Hytonen, V.P.,Maatta, J.A.,Nordlund, H.R.,Kulomaa, M.S.,Wilchek, M.,Bayer, E.A.,Livnah, O. Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester. Acta Crystallogr.,Sect.D 2008 64 302 308 2V2F 18055459 Crystal structure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae 2007-06-05 2007-12-25 Job, V.,Carapito, R.,Vernet, T.,Dessen, A.,Zapun, A. Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights. J.Biol.Chem. 2008 283 4886 0 3BI9 18083575 Tim-4 2007-11-30 2008-01-01 Santiago, C.,Ballesteros, A.,Martinez-Munoz, L.,Mellado, M.,Kaplan, G.G.,Freeman, G.J.,Casasnovas, J.M. Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity 2007 27 941 951 3BIA 18083575 Tim-4 in complex with sodium potassium tartrate 2007-11-30 2008-01-01 Santiago, C.,Ballesteros, A.,Martinez-Munoz, L.,Mellado, M.,Kaplan, G.G.,Freeman, G.J.,Casasnovas, J.M. Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity 2007 27 941 951 2OZ1 The SoxAX Complex of Rhodovulum Sulfidophilum 2007-02-23 2008-01-08 Kihlken, M.A.,Berks, B.C.,Hemmings, A.M. The crystal structure of recombinant Rhodovulum sulfidophilum SoxAX confirms cysteine persulfide coordination to the catalytic heme To be Published 0 0 0 0 2VFS 18154360 Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Xylitol 2007-11-05 2008-01-08 Forneris, F.,Heuts, D.P.H.M.,Delvecchio, M.,Rovida, S.,Fraaije, M.W.,Mattevi, A. Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry 2008 47 978 0 2VFT 18154360 Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sorbitol 2007-11-05 2008-01-08 Forneris, F.,Heuts, D.P.H.M.,Delvecchio, M.,Rovida, S.,Fraaije, M.W.,Mattevi, A. Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry 2008 47 978 0 2ODY 18286181 Thrombin-bound boophilin displays a functional and accessible reactive-site loop 2006-12-27 2008-01-22 Macedo-Ribeiro, S.,Almeida, C.,Calisto, B.M.,Friedrich, T.,Mentele, R.,Sturzebecher, J.,Fuentes-Prior, P.,Pereira, P.J. Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick. Plos One 2008 3 0 0 2ODY 18286181 Thrombin-bound boophilin displays a functional and accessible reactive-site loop 2006-12-27 2008-01-22 Macedo-Ribeiro, S.,Almeida, C.,Calisto, B.M.,Friedrich, T.,Mentele, R.,Sturzebecher, J.,Fuentes-Prior, P.,Pereira, P.J. Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick. Plos One 2008 3 0 0 2PMO 18275814 Crystal structure of PfPK7 in complex with hymenialdisine 2007-04-23 2008-01-22 Merckx, A.,Echalier, A.,Langford, K.,Sicard, A.,Langsley, G.,Joore, J.,Doerig, C.,Noble, M.,Endicott, J. Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design. Structure 2008 16 228 238 2VEE 18188182 Structure of protoglobin from Methanosarcina acetivorans C2A 2007-10-22 2008-01-22 Nardini, M.,Pesce, A.,Thijs, L.,Saito, J.A.,Dewilde, S.,Alam, M.,Ascenzi, P.,Coletta, M.,Ciaccio, C.,Moens, L.,Bolognesi, M. Archaeal Protoglobin Structure Indicates New Ligand Diffusion Paths and Modulation of Haem-Reactivity. Embo Rep. 2008 9 157 0 2QDQ 18157087 Crystal structure of the talin dimerisation domain 2007-06-21 2008-01-29 Gingras, A.R.,Bate, N.,Goult, B.T.,Hazelwood, L.,Canestrelli, I.,Grossmann, J.G.,Liu, H.,Putz, N.S.,Roberts, G.C.,Volkmann, N.,Hanein, D.,Barsukov, I.L.,Critchley, D.R. The structure of the C-terminal actin-binding domain of talin. Embo J. 2008 27 458 469 2JB8 Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid 2006-12-05 2008-02-05 Cicero, G.,Carbonera, C.,Valegard, K.,Hajdu, J.,Andersson, I.,Ranghino, G. Study of the Oxidative Half-Reaction Catalysed by a Non-Heme Ferrous Catalytic Centre by Means of Structural and Computational Methodologies Int.J.Quantum Chem. 2007 107 1514 0 2QLP 18164314 Bifunctional dCTP deaminase:dUTPase from Mycobacterium tuberculosis, apo form 2007-07-13 2008-02-19 Helt, S.S.,Thymark, M.,Harris, P.,Aagaard, C.,Dietrich, J.,Larsen, S.,Willemoes, M. Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis J.Mol.Biol. 2007 376 554 569 2QXX 18164314 Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP 2007-08-13 2008-02-19 Helt, S.S.,Thymark, M.,Harris, P.,Aagaard, C.,Dietrich, J.,Larsen, S.,Willemoes, M. Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis. J.Mol.Biol. 2008 376 554 569 2VDB 18259051 Structure of human serum albumin with S-naproxen and the GA module 2007-10-04 2008-02-26 Lejon, S.,Cramer, J.F.,Nordberg, P.A. Structural Basis for the Binding of Naproxen to Human Serum Albumin in the Presence of Fatty Acids and the Ga Module. Acta Crystallogr.,Sect.F 2008 64 64 0 2JIM 18327621 A New Catalytic Mechanism of Periplasmic Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774 from Crystallographic and EPR Data and based on detailed analysis of the sixth ligand 2007-06-28 2008-03-18 Najmudin, S.,Gonzalez, P.J.,Trincao, J.,Coelho, C.,Mukhopadhyay, A.,Cerqueira, N.M.F.S.A.,Romao, C.C.,Moura, I.,Moura, J.J.G.,Brondino, C.D.,Romao, M.J. Periplasmic Nitrate Reductase Revisited: A Sulfur Atom Completes the Sixth Coordination of the Catalytic Molybdenum. J.Biol.Inorg.Chem. 2008 13 737 0 2POS 17881828 Crystal Structure of sylvaticin, a new secreted protein from pythium sylvaticum 2007-04-27 2008-03-18 Lascombe, M.B.,Retailleau, P.,Ponchet, M.,Industri, B.,Blein, J.P.,Prange, T. Structure of sylvaticin, a new alpha-elicitin-like protein from Pythium sylvaticum. Acta Crystallogr.,Sect.D 2007 63 1102 1108 2V3V 18327621 A New Catalytic Mechanism of Periplasmic Nitrate Reductase from Desulfovibrio desulfuricans ATCC 27774 from Crystallographic and EPR Data and based on detailed analysis of the sixth ligand 2007-06-22 2008-03-18 Najmudin, S.,Gonzalez, P.J.,Trincao, J.,Coelho, C.,Mukhopadhyay, A.,Cerqueira, N.M.F.S.A.,Romao, C.C.,Moura, I.,Moura, J.J.G.,Brondino, C.D.,Romao, M.J. Periplasmic Nitrate Reductase Revisited: A Sulfur Atom Completes the Sixth Coordination of the Catalytic Molybdenum. J.Biol.Inorg.Chem. 2008 13 737 0 2VLB 18258259 Structure of unliganded arylmalonate decarboxylase 2008-01-11 2008-03-18 Kuettner, E.B.,Keim, A.,Kircher, M.,Rosmus, S.,Strater, N. Active Site Mobility Revealed by the Crystal Structure of Arylmalonate Decarboxylase from Bordetella Bronchiseptica J.Mol.Biol. 2008 377 386 0 2Q9O 18249560 Near-atomic resolution structure of a Melanocarpus albomyces laccase 2007-06-13 2008-03-25 Hakulinen, N.,Andberg, M.,Kallio, J.,Koivula, A.,Kruus, K.,Rouvinen, J. A near atomic resolution structure of a Melanocarpus albomyces laccase. J.Struct.Biol. 2008 162 29 39 2RDZ 18311941 High Resolution Crystal Structure of the Escherichia coli Cytochrome c Nitrite Reductase. 2007-09-25 2008-03-25 Clarke, T.A.,Kemp, G.L.,Wonderen, J.H.,Doyle, R.M.,Cole, J.A.,Tovell, N.,Cheesman, M.R.,Butt, J.N.,Richardson, D.J.,Hemmings, A.M. Role of a Conserved Glutamine Residue in Tuning the Catalytic Activity of Escherichia coli Cytochrome c Nitrite Reductase. Biochemistry 2008 47 3789 3799 3C1V 18435928 The 1.5 A Crystal structure of Ca2+-bound S100A4 2008-01-24 2008-04-01 Gingras, A.R.,Basran, J.,Prescott, A.,Kriajevska, M.,Bagshaw, C.R.,Barsukov, I.L. Crystal structure of the Ca(2+)-form and Ca(2+)-binding kinetics of metastasis-associated protein, S100A4 Febs Lett. 2008 582 1651 1656 2PRB 18292754 crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A 2007-05-04 2008-04-08 Maurice, F.,Broutin, I.,Podglajen, I.,Benas, P.,Collatz, E.,Dardel, F. Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep. 2008 9 344 349 2PZH 18338382 YbgC thioesterase (Hp0496) from Helicobacter pylori 2007-05-18 2008-04-08 Angelini, A.,Cendron, L.,Goncalves, S.,Zanotti, G.,Terradot, L. Structural and enzymatic characterization of HP0496, a YbgC thioesterase from Helicobacter pylori. 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Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus. J.Biol.Chem. 2007 282 23957 23969 2VOK 18420815 Murine TRIM21 2008-02-19 2008-04-15 Keeble, A.H.,Khan, Z.,Forster, A.,James, L.C. Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved. Proc.Natl.Acad.Sci.USA 2008 105 6045 0 3B8Y 18430740 Crystal Structure of Pectate Lyase PelI from Erwinia chrysanthemi in complex with tetragalacturonic acid 2007-11-02 2008-04-29 Creze, C.,Castang, S.,Derivery, E.,Haser, R.,Hugouvieux-Cotte-Pattat, N.,Shevchik, V.E.,Gouet, P. 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J.Mol.Biol. 2008 379 745 0 2VLP 18471830 R54A mutant of E9 DNase domain in complex with Im9 2008-01-15 2008-05-20 Keeble, A.H.,Joachimiak, L.A.,Mate, M.J.,Meenan, N.,Kirkpatrick, N.,Baker, D.,Kleanthous, C. Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases. J.Mol.Biol. 2008 379 745 0 2VLQ 18471830 F86A mutant of E9 DNase domain in complex with Im9 2008-01-15 2008-05-20 Keeble, A.H.,Joachimiak, L.A.,Mate, M.J.,Meenan, N.,Kirkpatrick, N.,Baker, D.,Kleanthous, C. Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases. J.Mol.Biol. 2008 379 745 0 2VQ2 18433773 Crystal structure of PilW, widely conserved type IV pilus biogenesis factor 2008-03-10 2008-05-27 Trindade, M.B.,Job, V.,Contreras-Martel, C.,Pelicic, V.,Dessen, A. Structure of a widely conserved type IV pilus biogenesis factor that affects the stability of secretin multimers. J. Mol. Biol. 2008 378 1031 1039 3BMV 18422488 Cyclodextrin glycosyl transferase from Thermoanerobacterium thermosulfurigenes EM1 mutant S77P 2007-12-13 2008-05-27 Kelly, R.M.,Leemhuis, H.,Rozeboom, H.J.,van Oosterwijk, N.,Dijkstra, B.W.,Dijkhuizen, L. Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution. Biochem.J. 2008 413 517 525 3BMW 18422488 Cyclodextrin glycosyl transferase from Thermoanerobacterium thermosulfurigenes EM1 mutant S77P complexed with a maltoheptaose inhibitor 2007-12-13 2008-05-27 Kelly, R.M.,Leemhuis, H.,Rozeboom, H.J.,van Oosterwijk, N.,Dijkstra, B.W.,Dijkhuizen, L. Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution. Biochem.J. 2008 413 517 525 2R6S 18391407 Crystal structure of Gab protein 2007-09-06 2008-06-03 Lohkamp, B.,Dobritzsch, D. 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Proc.Natl.Acad.Sci.Usa 2008 105 9065 9069 3BFA 18508083 Crystal structure of a pheromone binding protein from Apis mellifera in complex with the Queen mandibular pheromone 2007-11-21 2008-06-10 Pesenti, M.E.,Spinelli, S.,Bezirard, V.,Briand, L.,Pernollet, J.C.,Tegoni, M.,Cambillau, C. Structural basis of the honey bee PBP pheromone and pH-induced conformational change J.Mol.Biol. 2008 380 158 169 3CDN 18508083 Crystal structure of a pheromone binding protein from Apis mellifera soaked at pH 4.0 2008-02-27 2008-06-10 Pesenti, M.E.,Spinelli, S.,Bezirard, V.,Briand, L.,Pernollet, J.C.,Tegoni, M.,Cambillau, C. Structural basis of the honey bee PBP pheromone and pH-induced conformational change J.Mol.Biol. 2008 380 158 169 2VPD 18498752 Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex 2008-02-27 2008-06-17 Fiedler, M.,Sanchez-Barrena, M.J.,Nekrasov, M.,Mieszczanek, J.,Rybin, V.,Muller, J.,Evans, P.,Bienz, M. 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J.Mol.Biol. 2008 382 667 0 2VVG 18463165 Crystal Structure of the G.intestinalis Kinesin 2 GiKIN2a Motor Domain 2008-06-08 2008-07-08 Hoeng, J.C.,Dawson, S.C.,House, S.A.,Sagolla, M.S.,Pham, J.K.,Mancuso, J.J.,Loewe, J.,Cande, W.Z. High-Resolution Crystal Structure and in Vivo Function of a Kinesin-2 Homologue in Giardia Intestinalis. Mol.Biol.Cell 2008 19 3124 0 3CDU 18632861 Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate 2008-02-27 2008-07-22 Gruez, A.,Selisko, B.,Roberts, M.,Bricogne, G.,Bussetta, C.,Jabafi, I.,Coutard, B.,De Palma, A.M.,Neyts, J.,Canard, B. 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The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa. J.Biol.Chem. 2008 283 29416 29423 3CWN 18687684 Escherichia coli transaldolase b mutant f178y 2008-04-22 2008-08-05 Schneider, S.,Sandalova, T.,Schneider, G.,Sprenger, G.A.,Samland, A.K. Replacement of a Phenylalanine by a Tyrosine in the Active Site Confers Fructose-6-phosphate Aldolase Activity to the Transaldolase of Escherichia coli and Human Origin. J.Biol.Chem. 2008 283 30064 30072 3DEP 18621669 Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43 2008-06-10 2008-08-12 Stengel, K.F.,Holdermann, I.,Cain, P.,Robinson, C.,Wild, K.,Sinning, I. Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science 2008 321 253 256 3DLG 18665583 Crystal structure of hiv-1 reverse transcriptase in complex with GW564511. 2008-06-27 2008-08-12 Ren, J.,Chamberlain, P.P.,Stamp, A.,Short, S.A.,Weaver, K.L.,Romines, K.R.,Hazen, R.,Freeman, A.,Ferris, R.G.,Andrews, C.W.,Boone, L.,Chan, J.H.,Stammers, D.K. Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J.Med.Chem. 2008 51 5000 5008 3DM2 18665583 Crystal structure of HIV-1 K103N mutant reverse transcriptase in complex with GW564511. 2008-06-30 2008-08-12 Ren, J.,Chamberlain, P.P.,Stamp, A.,Short, S.A.,Weaver, K.L.,Romines, K.R.,Hazen, R.,Freeman, A.,Ferris, R.G.,Andrews, C.W.,Boone, L.,Chan, J.H.,Stammers, D.K. Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J.Med.Chem. 2008 51 5000 5008 3DMJ 18665583 CRYSTAL STRUCTURE OF HIV-1 V106A and Y181C MUTANT REVERSE TRANSCRIPTASE IN COMPLEX WITH GW564511. 2008-07-01 2008-08-12 Ren, J.,Chamberlain, P.P.,Stamp, A.,Short, S.A.,Weaver, K.L.,Romines, K.R.,Hazen, R.,Freeman, A.,Ferris, R.G.,Andrews, C.W.,Boone, L.,Chan, J.H.,Stammers, D.K. Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J.Med.Chem. 2008 51 5000 5008 2VSR 19172745 hPPARgamma Ligand binding domain in complex with 9-(S)-HODE 2008-04-29 2008-08-19 Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R. Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol. 2008 15 924 0 2VST 19172745 hPPARgamma Ligand binding domain in complex with 13-(S)-HODE 2008-04-29 2008-08-19 Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R. 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Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol. 2008 15 924 0 2VV3 19172745 hPPARgamma Ligand binding domain in complex with 4-oxoDHA 2008-06-02 2008-08-19 Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R. Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids. Nat.Struct.Mol.Biol. 2008 15 924 0 2VV4 19172745 hPPARgamma Ligand binding domain in complex with 6-oxoOTE 2008-06-02 2008-08-19 Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R. Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol. 2008 15 924 0 2QUY Truncated mutant ASN175ALA of penicillin v acylase from bacillus sphaericus 2007-08-07 2008-08-26 Pathak, M.C.,Brannigan, J.,Dodson, G.G.,Suresh, C.G. Auto-proteolytic processing of Penicillin V Acylase is simpler than of other related Ntn hydrolases To be Published 0 0 0 0 3D9S 18768791 Human Aquaporin 5 (AQP5) - High Resolution X-ray Structure 2008-05-27 2008-08-26 Horsefield, R.,Norden, K.,Fellert, M.,Backmark, A.,Tornroth-Horsefield, S.,Terwisscha van Scheltinga, A.C.,Kvassman, J.,Kjellbom, P.,Johanson, U.,Neutze, R. High-resolution x-ray structure of human aquaporin 5 Proc.Natl.Acad.Sci.Usa 2008 105 13327 13332 3CW5 18653533 E. coli Initiator tRNA 2008-04-21 2008-09-02 Barraud, P.,Schmitt, E.,Mechulam, Y.,Dardel, F.,Tisne, C. A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res. 2008 36 4894 4901 3CW6 18653533 E. coli Initiator tRNA 2008-04-21 2008-09-02 Barraud, P.,Schmitt, E.,Mechulam, Y.,Dardel, F.,Tisne, C. A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res. 2008 36 4894 4901 3D9W 18778714 Crystal Structure Analysis of Nocardia farcinica Arylamine N-acetyltransferase 2008-05-28 2008-09-02 Martins, M.,Pluvinage, B.,Li de la Sierra-Gallay, I.,Barbault, F.,Dairou, J.,Dupret, J.M.,Rodrigues-Lima, F. Functional and structural characterization of the arylamine N-acetyltransferase from the opportunistic pathogen Nocardia farcinica J.Mol.Biol. 2008 383 549 560 3E3K 18759453 Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA (butane-1,2,4-tricarboxylate without nickel form) 2008-08-07 2008-09-16 Cherrier, M.V.,Cavazza, C.,Bochot, C.,Lemaire, D.,Fontecilla-Camps, J.C. Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA Biochemistry 2008 47 9937 9943 2VAX 18279889 Crystal structure of deacetylcephalosporin C acetyltransferase (Cephalosporin C-soak) 2007-09-04 2008-09-23 Lejon, S.,Ellis, J.,Valegard, K. The Last Step in Cephalosporin C Formation Revealed: Crystal Structures of Deacetylcephalosporin C Acetyltransferase from Acremonium Chrysogenum in Complexes with Reaction Intermediates. J.Mol.Biol. 2008 377 935 0 3CXZ Crystal structure of cytochrome P450 CYP121 R386L mutant from M. tuberculosis 2008-04-25 2008-09-23 McLean, K.J.,Carrol, P.,Lewis, D.G.,Dunford, A.J.,Seward, H.E.,Neeli, R.,Cole, S.T.,Leys, D.,Parish, T.,Munro, A.W. Characterization of active site structure of cytochrome P450 CYP121 TO BE PUBLISHED 0 0 0 0 3CY0 Crystal structure of cytochrome P450 CYP121 S237A mutant from Mycobacterium tuberculosis 2008-04-25 2008-09-23 McLean, K.J.,Carrol, P.,Lewis, D.G.,Dunford, A.J.,Seward, H.E.,Neeli, R.,Cole, S.T.,Parish, T.,Leys, D.,Munro, A.W. Characterisation of active site structure of cytochrome CYP121 TO BE PUBLISHED 0 0 0 0 2VDH 18072944 Crystal structure of Chlamydomonas reinhardtii Rubisco with a large- subunit C172S mutation 2007-10-09 2008-11-04 Garcia-Murria, M.-J.,Karkehabadi, S.,Marin-Navarro, J.,Satagopan, S.,Andersson, I.,Spreitzer, R.J.,Moreno, J. Structural and Functional Consequences of the Replacement of Proximal Residues Cys-172 and Cys-192 in the Large Subunit of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase from Chlamydomonas Reinhardtii Biochem.J. 2008 411 241 0 3E2T 18937498 The catalytic domain of chicken tryptophan hydroxylase 1 with bound tryptophan 2008-08-06 2008-11-04 Windahl, M.S.,Petersen, C.R.,Christensen, H.E.M.,Harris, P. Crystal structure of tryptophan hydroxylase with bound amino acid substrate Biochemistry 2008 47 12087 12094 2VNI 18973834 X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH 2P-AMP AT 2.37 ANGSTROMS RESOLUTION 2008-02-05 2008-11-11 Bortolotti, A.,Perez-Dorado, I.,Goni, G.,Medina, M.,Hermoso, J.A.,Carrillo, N.,Cortez, N. Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase. Biochim.Biophys.Acta 2009 1794 199 0 2VVH 19017808 IrisFP fluorescent protein in its green form, cis conformation 2008-06-09 2008-11-11 Adam, V.,Lelimousin, M.,Boehme, S.,Desfonds, G.,Nienhaus, K.,Field, M.J.,Wiedenmann, J.,Mcsweeney, S.,Nienhaus, G.U.,Bourgeois, D. Structural Characterization of Irisfp, an Optical Highlighter Undergoing Multiple Photo-Induced Transformations. Proc.Natl.Acad.Sci.USA 2008 105 18343 0 2VVI 19017808 IrisFP fluorescent protein in its green form, trans conformation 2008-06-09 2008-11-11 Adam, V.,Lelimousin, M.,Boehme, S.,Desfonds, G.,Nienhaus, K.,Field, M.J.,Wiedenmann, J.,Mcsweeney, S.,Nienhaus, G.U.,Bourgeois, D. Structural Characterization of Irisfp, an Optical Highlighter Undergoing Multiple Photo-Induced Transformations. Proc.Natl.Acad.Sci.USA 2008 105 18343 0 2W2O 19001363 PCSK9-deltaC D374Y mutant bound to WT EGF-A of LDLR 2008-11-03 2008-11-18 Bottomley, M.J.,Cirillo, A.,Orsatti, L.,Ruggeri, L.,Fisher, T.S.,Santoro, J.C.,Cummings, R.T.,Cubbon, R.M.,Lo Surdo, P.,Calzetta, A.,Noto, A.,Baysarowich, J.,Mattu, M.,Talamo, F.,De Francesco, R.,Sparrow, C.P.,Sitlani, A.,Carfi, A. Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. J.Biol.Chem. 2009 284 1313 0 3ELW 18976670 Wesselsbron virus Methyltransferase in complex with AdoMet and GpppG 2008-09-23 2008-11-18 Bollati, M.,Milani, M.,Mastrangelo, E.,Ricagno, S.,Tedeschi, G.,Nonnis, S.,Decroly, E.,Selisko, B.,de Lamballerie, X.,Coutard, B.,Canard, B.,Bolognesi, M. Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol. 2009 385 140 152 3BLY 19143837 Pyranose 2-oxidase from Trametes multicolor, E542K/L537W 2007-12-11 2008-12-02 Spadiut, O.,Leitner, C.,Salaheddin, C.,Varga, B.,Vertessy, B.G.,Tan, T.C.,Divne, C.,Haltrich, D. 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Structural Characterizations of Glycerol Kinase: Unraveling Phosphorylation-Induced Long-Range Activation Biochemistry 2008 0 0 0 3DD6 19153445 Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution 2008-06-05 2009-02-10 Rawlings, A.E.,Blagova, E.V.,Levdikov, V.M.,Fogg, M.J.,Wilson, K.S.,Wilkinson, A.J. The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution. Acta Crystallogr.,Sect.F 2009 65 2 7 3FID 19174515 LpxR from Salmonella typhimurium 2008-12-11 2009-02-10 Rutten, L.,Mannie, J.-P.B.A.,Stead, C.M.,Raetz, C.R.H.,Reynolds, C.M.,Bonvin, A.M.J.J.,Tommassen, J.P.,Egmond, M.R.,Trent, M.S.,Gros, P. Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium Proc.Natl.Acad.Sci.USA 2009 106 1960 1964 2WAD 19233207 PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204) 2009-02-05 2009-02-24 Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci J.Mol.Biol. 2009 387 899 0 3CLL 19302796 Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E mutant 2008-03-19 2009-02-24 Nyblom, M.,Frick, A.,Wang, Y.,Ekvall, M.,Hallgren, K.,Hedfalk, K.,Neutze, R.,Tajkhorshid, E.,Tornroth-Horsefield, S. Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. 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