PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 1REQ METHYLMALONYL-COA MUTASE 1996-01-19 1997-01-27 Mancia, F.,Keep, N.H.,Nakagawa, A.,Leadlay, P.F.,McSweeney, S.,Rasmussen, B.,Bosecke, P.,Diat, O.,Evans, P.R. How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution. Structure 1996 4 339 350 1XIK RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN 1996-08-06 1997-03-12 Logan, D.T.,Su, X.D.,Aberg, A.,Regnstrom, K.,Hajdu, J.,Eklund, H.,Nordlund, P. Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site. Structure 1996 4 1053 1064 1AFW THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE 1997-03-15 1997-06-16 Mathieu, M.,Modis, Y.,Zeelen, J.P.,Engel, C.K.,Abagyan, R.A.,Ahlberg, A.,Rasmussen, B.,Lamzin, V.S.,Kunau, W.H.,Wierenga, R.K. The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism. J.Mol.Biol. 1997 273 714 728 1AGC ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION) 1997-03-24 1997-06-16 Reid, S.W.,McAdam, S.,Smith, K.J.,Klenerman, P.,O'Callaghan, C.A.,Harlos, K.,Jakobsen, B.K.,McMichael, A.J.,Bell, J.I.,Stuart, D.I.,Jones, E.Y. Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med. 1996 184 2279 2286 1AGF ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKRYKL-5R MUTATION) 1997-03-24 1997-06-16 Reid, S.W.,McAdam, S.,Smith, K.J.,Klenerman, P.,O'Callaghan, C.A.,Harlos, K.,Jakobsen, B.K.,McMichael, A.J.,Bell, J.I.,Stuart, D.I.,Jones, E.Y. Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med. 1996 184 2279 2286 1DJG PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH LANTHANUM 1996-09-25 1997-07-07 Essen, L.O.,Perisic, O.,Lynch, D.E.,Katan, M.,Williams, R.L. A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1. Biochemistry 1997 36 2753 2762 1DJX PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-1,4,5-TRISPHOSPHATE 1996-08-24 1997-07-07 Essen, L.O.,Perisic, O.,Katan, M.,Wu, Y.,Roberts, M.F.,Williams, R.L. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C. Biochemistry 1997 36 1704 1718 1DJY PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2,4,5-TRISPHOSPHATE 1996-08-24 1997-07-07 Essen, L.O.,Perisic, O.,Katan, M.,Wu, Y.,Roberts, M.F.,Williams, R.L. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C. Biochemistry 1997 36 1704 1718 1DJZ PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-4,5-BISPHOSPHATE 1996-08-24 1997-07-07 Essen, L.O.,Perisic, O.,Katan, M.,Wu, Y.,Roberts, M.F.,Williams, R.L. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C. Biochemistry 1997 36 1704 1718 1DJW PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHONATE 1996-08-24 1997-07-23 Essen, L.O.,Perisic, O.,Katan, M.,Wu, Y.,Roberts, M.F.,Williams, R.L. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C. Biochemistry 1997 36 1704 1718 1ADJ HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE 1997-02-18 1997-08-20 Aberg, A.,Yaremchuk, A.,Tukalo, M.,Rasmussen, B.,Cusack, S. Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase. Biochemistry 1997 36 3084 3094 1ADY HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDYL-ADENYLATE 1997-02-19 1997-08-20 Aberg, A.,Yaremchuk, A.,Tukalo, M.,Rasmussen, B.,Cusack, S. Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase. Biochemistry 1997 36 3084 3094 1WER RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP 1996-11-20 1997-12-31 Scheffzek, K.,Lautwein, A.,Kabsch, W.,Ahmadian, M.R.,Wittinghofer, A. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature 1996 384 591 596 1KLM HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152 1997-03-17 1998-03-18 Esnouf, R.M.,Ren, J.,Hopkins, A.L.,Ross, C.K.,Jones, E.Y.,Stammers, D.K.,Stuart, D.I. Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. Proc.Natl.Acad.Sci.USA 1997 94 3984 3989 1IPS ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX) 1997-03-21 1998-03-25 Roach, P.L.,Clifton, I.J.,Fulop, V.,Harlos, K.,Barton, G.J.,Hajdu, J.,Andersson, I.,Schofield, C.J.,Baldwin, J.E. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature 1995 375 700 704 2FRV CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE 1997-06-10 1998-06-17 Volbeda, A.,Garcin, E.,Piras, C.,De Lacey, A.L.,Fernandez, V.M.,Hatchikian, E.C.,Frey, M.,Fontecilla-Camps, J.C. Structure of the [Nife] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe Ligands J.Am.Chem.Soc. 1996 118 12989 0 5MSF MS2 PROTEIN CAPSID/RNA COMPLEX 1998-05-15 1998-11-11 Rowsell, S.,Stonehouse, N.J.,Convery, M.A.,Adams, C.J.,Ellington, A.D.,Hirao, I.,Peabody, D.S.,Stockley, P.G.,Phillips, S.E. Crystal structures of a series of RNA aptamers complexed to the same protein target. Nat.Struct.Biol. 1998 5 970 975 7MSF MS2 PROTEIN CAPSID/RNA COMPLEX 1998-05-20 1998-11-11 Rowsell, S.,Stonehouse, N.J.,Convery, M.A.,Adams, C.J.,Ellington, A.D.,Hirao, I.,Peabody, D.S.,Stockley, P.G.,Phillips, S.E. Crystal structures of a series of RNA aptamers complexed to the same protein target. Nat.Struct.Biol. 1998 5 970 975 1ZDK STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX 1998-12-04 1998-12-07 Grahn, E.,Stonehouse, N.J.,Murray, J.B.,van den Worm, S.,Valegard, K.,Fridborg, K.,Stockley, P.G.,Liljas, L. Crystallographic studies of RNA hairpins in complexes with recombinant MS2 capsids: implications for binding requirements. RNA 1999 5 131 138 1914 SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14 1997-11-13 1998-12-30 Birse, D.E.,Kapp, U.,Strub, K.,Cusack, S.,Aberg, A. The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14. EMBO J. 1997 16 3757 3766 1BGY CYTOCHROME BC1 COMPLEX FROM BOVINE 1998-06-02 1999-01-06 Iwata, S.,Lee, J.W.,Okada, K.,Lee, J.K.,Iwata, M.,Rasmussen, B.,Link, T.A.,Ramaswamy, S.,Jap, B.K. Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex. Science 1998 281 64 71 1BE3 CYTOCHROME BC1 COMPLEX FROM BOVINE 1998-05-19 1999-01-13 Iwata, S.,Lee, J.W.,Okada, K.,Lee, J.K.,Iwata, M.,Rasmussen, B.,Link, T.A.,Ramaswamy, S.,Jap, B.K. Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex. Science 1998 281 64 71 1BG1 TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX 1998-06-03 1999-01-13 Becker, S.,Groner, B.,Muller, C.W. Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature 1998 394 145 151 1BLZ ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE-NO COMPLEX) 1998-07-22 1999-01-13 Roach, P.L.,Clifton, I.J.,Hensgens, C.M.,Shibata, N.,Schofield, C.J.,Hajdu, J.,Baldwin, J.E. Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature 1997 387 827 830 1QF6 10319817 STRUCTURE OF E. COLI THREONYL-TRNA SYNTHETASE COMPLEXED WITH ITS COGNATE TRNA 1999-04-06 1999-05-06 Sankaranarayanan, R.,Dock-Bregeon, A.C.,Romby, P.,Caillet, J.,Springer, M.,Rees, B.,Ehresmann, C.,Ehresmann, B.,Moras, D. The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site Cell(Cambridge,Mass.) 1999 97 371 381 1SUR PHOSPHO-ADENYLYL-SULFATE REDUCTASE 1998-04-01 1999-05-11 Savage, H.,Montoya, G.,Svensson, C.,Schwenn, J.D.,Sinning, I. Crystal structure of phosphoadenylyl sulphate (PAPS) reductase: a new family of adenine nucleotide alpha hydrolases. Structure 1997 5 895 906 1QGK 10353244 STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA 1999-04-29 1999-05-24 Cingolani, G.,Petosa, C.,Weis, K.,Muller, C.W. Structure of importin-beta bound to the IBB domain of importin-alpha. Nature 1999 399 221 229 1QGT 10394365 HUMAN HEPATITIS B VIRAL CAPSID (HBCAG) 1999-05-05 1999-06-25 Wynne, S.A.,Crowther, R.A.,Leslie, A.G. The crystal structure of the human hepatitis B virus capsid. Mol.Cell 1999 3 771 780 1BVO 10425685 DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA 1998-09-16 1999-07-12 Cramer, P.,Varrot, A.,Barillas-Mury, C.,Kafatos, F.C.,Muller, C.W. Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA. Structure Fold.Des. 1999 7 841 852 1MJQ 10986458 METHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO AN ALTERED MET CONSENSUS OPERATOR SEQUENCE 1998-01-30 1999-08-02 Garvie, C.W.,Phillips, S.E. Direct and indirect readout in mutant Met repressor-operator complexes. Structure Fold.Des. 2000 8 905 914 1QHV 10502512 HUMAN ADENOVIRUS SEROTYPE 2 FIBRE HEAD 1999-05-28 1999-09-29 van Raaij, M.J.,Louis, N.,Chroboczek, J.,Cusack, S. Structure of the human adenovirus serotype 2 fiber head domain at 1.5 A resolution. Virology 1999 262 333 343 1QD6 10537112 OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI 1999-07-09 1999-10-25 Snijder, H.J.,Ubarretxena-Belandia, I.,Blaauw, M.,Kalk, K.H.,Verheij, H.M.,Egmond, M.R.,Dekker, N.,Dijkstra, B.W. Structural evidence for dimerization-regulated activation of an integral membrane phospholipase. Nature 1999 401 717 721 1QO1 10576729 Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria 1999-11-01 1999-11-04 Stock, D.,Leslie, A.G.W.,Walker, J.E. Molecular Architecture of the Rotary Motor in ATP Synthase Science 1999 286 1700 0 1QLE 10559205 CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT 1999-08-30 1999-12-02 Harrenga, A.,Michel, H. The Cytochrome C Oxidase from Paracoccus Denitrificans Does not Change the Metal Center Ligation Upon Reduction J.Biol.Chem. 1999 274 33296 0 1CL7 10631984 ANTI HIV1 PROTEASE FAB 1999-05-06 2000-01-12 Lescar, J.,Brynda, J.,Rezacova, P.,Stouracova, R.,Riottot, M.M.,Chitarra, V.,Fabry, M.,Horejsi, M.,Sedlacek, J.,Bentley, G.A. Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody. Protein Sci. 1999 8 2686 2696 1DV4 10588692 PARTIAL STRUCTURE OF 16S RNA OF THE SMALL RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS 2000-01-19 2000-02-02 Tocilj, A.,Schlunzen, F.,Janell, D.,Gluhmann, M.,Hansen, H.A.,Harms, J.,Bashan, A.,Bartels, H.,Agmon, I.,Franceschi, F.,Yonath, A. The small ribosomal subunit from Thermus thermophilus at 4.5 A resolution: pattern fittings and the identification of a functional site. Proc.Natl.Acad.Sci.USA 1999 96 14252 14257 1DYU 10387067 The active site base controls cofactor reactivity in Escherichia coli amine oxidase: X-ray crystallographic studies with mutational variants. 2000-02-08 2000-02-29 Murray, J.M.,Wilmot, C.M.,Saysell, C.G.,Jaeger, J.,Knowles, P.F.,Phillips, S.E.V.,McPherson, M.J. The Active Site Base Controls Cofactor Reactivity in Escherichia Coli Amine Oxidase : X-Ray Crystallographicstudies with Mutational Variants Biochemistry 1999 38 8217 0 1EO8 10899782 INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY 2000-03-22 2000-04-12 Fleury, D.,Daniels, R.S.,Skehel, J.J.,Knossow, M.,Bizebard, T. Structural evidence for recognition of a single epitope by two distinct antibodies. Proteins 2000 40 572 578 1EQ6 10860733 1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P 2000-04-03 2000-05-27 Stewart, M.,Baker, R.P. 1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p. J.Mol.Biol. 2000 299 213 223 1E1Q 10873854 BOVINE MITOCHONDRIAL F1-ATPASE AT 100K 2000-05-10 2000-06-28 Braig, K.,Menz, R.I.,Montgomery, M.G.,Leslie, A.G.W.,Walker, J.E. Structure of Bovine Mitochondrial F1-ATPase Inhibited by Mg2+Adp and Aluminium Fluoride Structure 2000 8 567 0 1C0T 10508433 CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+21.1326 1999-07-19 2000-07-19 Ren, J.,Esnouf, R.M.,Hopkins, A.L.,Stuart, D.I.,Stammers, D.K. Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. J.Med.Chem. 1999 42 3845 3851 1F5N 10970849 HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP. 2000-06-15 2000-09-27 Prakash, B.,Renault, L.,Praefcke, G.J.,Herrmann, C.,Wittinghofer, A. Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J. 2000 19 4555 4564 1E8X 11090628 STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING 2000-10-03 2000-10-26 Walker, E.H.,Pacold, M.E.,Perisic, O.,Stephens, L.,Hawkins, P.T.,Whymann, M.P.,Williams, R.L. Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell 2000 6 909 0 1G1K 11080455 COHESIN MODULE FROM THE CELLULOSOME OF CLOSTRIDIUM CELLULOLYTICUM 2000-10-12 2000-11-22 Spinelli, S.,Fierobe, H.P.,Belaich, A.,Belaich, J.P.,Henrissat, B.,Cambillau, C. Crystal structure of a cohesin module from Clostridium cellulolyticum: implications for dockerin recognition. J.Mol.Biol. 2000 304 189 200 1EWY 11053838 ANABAENA PCC7119 FERREDOXIN:FERREDOXIN-NADP+-REDUCTASE COMPLEX 2000-04-28 2001-02-07 Morales, R.,Kachalova, G.,Vellieux, F.,Charon, M.H.,Frey, M. Crystallographic studies of the interaction between the ferredoxin-NADP+ reductase and ferredoxin from the cyanobacterium Anabaena: looking for the elusive ferredoxin molecule. Acta Crystallogr.,Sect.D 2000 56 1408 1412 1FE1 11217865 CRYSTAL STRUCTURE PHOTOSYSTEM II 2000-07-20 2001-02-14 Zouni, A.,Witt, H.T.,Kern, J.,Fromme, P.,Krauss, N.,Saenger, W.,Orth, P. Crystal structure of photosystem II from Synechococcus elongatus at 3.8 A resolution. Nature 2001 409 739 743 1I2M 11336674 RAN-RCC1-SO4 COMPLEX 2001-02-11 2001-05-02 Renault, L.,Kuhlmann, J.,Henkel, A.,Wittinghofer, A. Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell(Cambridge,Mass.) 2001 105 245 255 1H4Q 11399074 Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG), ATP and prolinol 2001-05-13 2001-06-18 Yaremchuk, A.,Tukalo, M.,Grotli, M.,Cusack, S. A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase J.Mol.Biol. 2001 309 989 0 1H4S 11399074 Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG) and a prolyl-adenylate analogue 2001-05-14 2001-06-18 Yaremchuk, A.,Tukalo, M.,Grotli, M.,Cusack, S. A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase J.Mol.Biol. 2001 309 989 0 1H4V 11399074 HISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free) 2001-05-14 2001-06-18 Yaremchuk, A.,Tukalo, M.,Grotli, M.,Cusack, S. A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase J.Mol.Biol. 2001 309 989 0 1ILX 11459991 Excited State Dynamics in Photosystem II Revised. New Insights from the X-ray Structure. 2001-05-09 2001-07-18 Vasil'ev, S.,Orth, P.,Zouni, A.,Owens, T.G.,Bruce, D. Excited-state dynamics in photosystem II: insights from the x-ray crystal structure. Proc.Natl.Acad.Sci.USA 2001 98 8602 8607 1JB0 11418848 Crystal Structure of Photosystem I: a Photosynthetic Reaction Center and Core Antenna System from Cyanobacteria 2001-06-01 2001-08-01 Jordan, P.,Fromme, P.,Witt, H.T.,Klukas, O.,Saenger, W.,Krauss, N. Three-dimensional Structure of Cyanobacterial Photosystem I at 2.5 A Resolution NATURE 2001 411 909 917 1JB0 11418848 Crystal Structure of Photosystem I: a Photosynthetic Reaction Center and Core Antenna System from Cyanobacteria 2001-06-01 2001-08-01 Jordan, P.,Fromme, P.,Witt, H.T.,Klukas, O.,Saenger, W.,Krauss, N. Three-dimensional Structure of Cyanobacterial Photosystem I at 2.5 A Resolution NATURE 2001 411 909 917 1H8N 11397090 Three-dimensional structure of anti-ampicillin single chain Fv fragment from phage-displayed murine antibody libraries 2001-02-14 2001-08-02 Jung, S.,Spinelli, S.,Schimmele, B.,Honegger, A.,Pugliese, L.,Cambillau, C.,Pluckthun, A. The Importance of Framework Residues H6, H7 and H10 in Antibody Heavy Chains: Experimental Evidence for a New Structural Subclassification of Antibody V(H) Domains J.Mol.Biol. 2001 309 701 0 1I3U 11469862 THREE-DIMENSIONAL STRUCTURE OF A LLAMA VHH DOMAIN COMPLEXED WITH THE DYE RR1 2001-02-16 2001-08-08 Spinelli, S.,Tegoni, M.,Frenken, L.,van Vliet, C.,Cambillau, C. Lateral recognition of a dye hapten by a llama VHH domain. J.Mol.Biol. 2001 311 123 129 1JLE 11575933 CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE 2001-07-16 2001-10-03 Ren, J.,Nichols, C.,Bird, L.,Chamberlain, P.,Weaver, K.,Short, S.,Stuart, D.I.,Stammers, D.K. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J.Mol.Biol. 2001 312 795 805 1H8T 12097583 Echovirus 11 2001-02-15 2002-07-11 Stuart, A.,Mckee, T.,Williams, P.A.,Harley, C.,Shen, S.,Stuart, D.I.,Brown, T.D.K.,Lea, S.M. Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection J.Virol. 2002 76 7694 0 1M6N 12242434 Crystal structure of the SecA translocation ATPase from Bacillus subtilis 2002-07-16 2002-09-20 Hunt, J.F.,Weinkauf, S.,Henry, L.,Fak, J.J.,McNicholas, P.,Oliver, D.B.,Deisenhofer, J. Nucleotide Control of Interdomain Interactions in the Conformational Reaction Cycle of SecA Science 2002 297 2018 2026 1M74 12242434 Crystal structure of Mg-ADP-bound SecA from Bacillus subtilis 2002-07-16 2002-09-20 Hunt, J.F.,Weinkauf, S.,Henry, L.,Fak, J.J.,McNicholas, P.,Oliver, D.B.,Deisenhofer, J. Nucleotide Control of Interdomain Interactions in the Conformational Reaction Cycle of SecA Science 2002 297 2018 2026 1H1K 12186935 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA 2002-07-17 2002-09-26 Diprose, J.M.,Grimes, J.M.,Sutton, G.C.,Burroughs, J.N.,Meyer, A.,Maan, S.,Mertens, P.P.C.,Stuart, D.I. The Core of Bluetongue Virus Binds Double-Stranded RNA J.Virol. 2002 76 9533 0 1LW0 12208978 CRYSTAL STRUCTURE OF T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE 2002-05-30 2002-10-30 Chamberlain, P.P.,Ren, J.,Nichols, C.E.,Douglas, L.,Lennerstrand, J.,Larder, B.A.,Stuart, D.I.,Stammers, D.K. Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. J.Virol. 2002 76 10015 10019 1LWC 12208978 CRYSTAL STRUCTURE OF M184V MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE 2002-05-31 2002-10-30 Chamberlain, P.P.,Ren, J.,Nichols, C.E.,Douglas, L.,Lennerstrand, J.,Larder, B.A.,Stuart, D.I.,Stammers, D.K. Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. J.Virol. 2002 76 10015 10019 1NN0 12614151 Crystal structure of human thymidylate kinase with ddTMP and ADP 2003-01-12 2003-03-18 Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds Biochemistry 2003 42 2568 2577 1N4X 12777823 Structure of scFv 1696 at acidic pH 2002-11-02 2003-06-10 Lescar, J.,Brynda, J.,Fabry, M.,Horejsi, M.,Rezacova, P.,Sedlacek, J.,Bentley, G.A. Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases. Acta Crystallogr.,Sect.D 2003 59 955 957 1R70 15111057 Model of human IgA2 determined by solution scattering, curve fitting and homology modelling 2003-10-17 2004-10-19 Furtado, P.B.,Whitty, P.W.,Robertson, A.,Eaton, J.T.,Almogren, A.,Kerr, M.A.,Woof, J.M.,Perkins, S.J. Solution Structure Determination of Monomeric Human IgA2 by X-ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Modelling: A Comparison with Monomeric Human IgA1. J.Mol.Biol. 2004 338 921 941 2BFI 15630094 Molecular basis for amyloid fibril formation and stability 2004-12-07 2005-01-06 Sumner Makin, O.,Atkins, E.,Sikorski, P.,Johansson, J.,Serpell, L.C. Molecular Basis for Amyloid Fibril Formation and Stability Proc.Natl.Acad.Sci.USA 2005 102 315 0 1ZVO 16157351 Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering 2005-06-02 2005-10-25 Sun, Z.,Almogren, A.,Furtado, P.B.,Chowdhury, B.,Kerr, M.A.,Perkins, S.J. Semi-extended Solution Structure of Human Myeloma Immunoglobulin D Determined by Constrained X-ray Scattering. J.Mol.Biol. 2005 353 155 173 2ESG 16376934 Solution structure of the complex between immunoglobulin IgA1 and human serum albumin 2005-10-26 2006-01-31 Almogren, A.,Furtado, P.B.,Sun, Z.,Perkins, S.J.,Kerr, M.A. Purification, Properties and Extended Solution Structure of the Complex Formed between Human Immunoglobulin A1 and Human Serum Albumin by Scattering and Ultracentrifugation. J.Mol.Biol. 2006 356 413 431 1ZLG 15949815 Solution structure of the extracellular matrix protein anosmin-1 2005-05-06 2006-05-09 Hu, Y.,Sun, Z.,Eaton, J.T.,Bouloux, P.M.,Perkins, S.J. Extended and Flexible Domain Solution Structure of the Extracellular Matrix Protein Anosmin-1 by X-ray Scattering, Analytical Ultracentrifugation and Constrained Modelling. J.Mol.Biol. 2005 350 553 570 2DRU 16803907 Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD48 2006-06-15 2006-07-04 Evans, E.J.,Castro, M.A.A.,O'Brien, R.,Kearney, A.,Walsh, H.,Sparks, L.M.,Tucknott, M.G.,Davies, E.A.,Carmo, A.M.,van der Merwe, P.A.,Stuart, D.I.,Jones, E.Y.,Ladbury, J.E.,Ikemizu, S.,Davis, S.J. Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48 J.Biol.Chem. 2006 281 29309 29320 2DRU 16803907 Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD48 2006-06-15 2006-07-04 Evans, E.J.,Castro, M.A.A.,O'Brien, R.,Kearney, A.,Walsh, H.,Sparks, L.M.,Tucknott, M.G.,Davies, E.A.,Carmo, A.M.,van der Merwe, P.A.,Stuart, D.I.,Jones, E.Y.,Ladbury, J.E.,Ikemizu, S.,Davis, S.J. Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48 J.Biol.Chem. 2006 281 29309 29320 2GSX 16950392 Complement Receptor Type 2 2006-04-27 2006-09-26 Gilbert, H.E.,Asokan, R.,Holers, V.M.,Perkins, S.J. The 15 SCR Flexible Extracellular Domains of Human Complement Receptor Type 2 can Mediate Multiple Ligand and Antigen Interactions. J.Mol.Biol. 2006 362 1132 1147 2OPP 17441703 Crystal Structure of HIV-1 Reverse Transcriptase in Complex with GW420867X. 2007-01-30 2007-05-22 Ren, J.,Nichols, C.E.,Chamberlain, P.P.,Weaver, K.L.,Short, S.A.,Chan, J.H.,Kleim, J.P.,Stammers, D.K. Relationship of Potency and Resilience to Drug Resistant Mutations for GW420867X Revealed by Crystal Structures of Inhibitor Complexes for Wild-Type, Leu100Ile, Lys101Glu, and Tyr188Cys Mutant HIV-1 Reverse Transcriptases. J.Med.Chem. 2007 50 2301 2309 3CHN 19079336 Solution structure of human secretory IgA1 2008-03-10 2008-12-30 Bonner, A.,Almogren, A.,Furtado, P.B.,Kerr, M.A.,Perkins, S.J. Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity. Mucosal Immunol 2009 2 74 84 3CM9 19109255 Solution Structure of Human SIgA2 2008-03-21 2008-12-30 Bonner, A.,Almogren, A.,Furtado, P.B.,Kerr, M.A.,Perkins, S.J. The nonplanar secretory IgA2 and near planar secretory IgA1 solution structures rationalize their different mucosal immune responses. J.Biol.Chem. 2009 284 5077 5087 3GAU 19505476 Solution structure of Human Complement Factor H in 50 mM NaCl buffer 2009-02-18 2009-06-09 Okemefuna, A.I.,Nan, R.,Gor, J.,Perkins, S.J. Electrostatic interactions contribute to the folded-back conformation of wild type human factor H. J.Mol.Biol. 2009 391 98 118 3GAV 19505476 Solution structure of Human Complement Factor H in 137 mM NaCl buffer 2009-02-18 2009-06-09 Okemefuna, A.I.,Nan, R.,Gor, J.,Perkins, S.J. Electrostatic interactions contribute to the folded-back conformation of wild type human factor H. J.Mol.Biol. 2009 391 98 118 3GAW 19505476 Solution structure of Human Complement Factor H in 250 mM NaCl buffer 2009-02-18 2009-06-09 Okemefuna, A.I.,Nan, R.,Gor, J.,Perkins, S.J. Electrostatic interactions contribute to the folded-back conformation of wild type human factor H. J.Mol.Biol. 2009 391 98 118 3IRI 19895822 Solution Structure of Heparin dp18 2009-08-24 2009-11-03 Khan, S.,Gor, J.,Mulloy, B.,Perkins, S.J. Semi-rigid solution structures of heparin by constrained X-ray scattering modelling: new insight into heparin-protein complexes. J.Mol.Biol. 2010 395 504 521 3IRJ 19895822 Solution Structure of Heparin dp24 2009-08-24 2009-11-03 Khan, S.,Gor, J.,Mulloy, B.,Perkins, S.J. Semi-rigid solution structures of heparin by constrained X-ray scattering modelling: new insight into heparin-protein complexes. J.Mol.Biol. 2010 395 504 521 3IRK 19895822 Solution Structure of Heparin dp30 2009-08-24 2009-11-03 Khan, S.,Gor, J.,Mulloy, B.,Perkins, S.J. Semi-rigid solution structures of heparin by constrained X-ray scattering modelling: new insight into heparin-protein complexes. J.Mol.Biol. 2010 395 504 521 3IRL 19895822 Solution Structure of Heparin dp36 2009-08-24 2009-11-03 Khan, S.,Gor, J.,Mulloy, B.,Perkins, S.J. Semi-rigid solution structures of heparin by constrained X-ray scattering modelling: new insight into heparin-protein complexes. J.Mol.Biol. 2010 395 504 521 4GXD 23519669 Crystal structure of D48V mutant of human GLTP bound with 12:0 disulfatide 2012-09-04 2013-04-10 Samygina, V.R.,Ochoa-Lizarralde, B.,Popov, A.N.,Cabo-Bilbao, A.,Goni-de-Cerio, F.,Molotkovsky, J.G.,Patel, D.J.,Brown, R.E.,Malinina, L. Structural insights into lipid-dependent reversible dimerization of human GLTP. Acta Crystallogr.,Sect.D 2013 69 603 616 5IQP 14-3-3 PROTEIN TAU ISOFORM 2016-03-11 2016-03-23 Xiao, B.,Smerdon, S.J.,Jones, D.H.,Dodson, G.G.,Soneji, Y.,Aitken, A.,Gamblin, S.J. Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways Nature 1995 376 188 191 8A58 37061529 X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W 2022-06-14 2023-04-26 Kiss, L.,Rhinesmith, T.,Luptak, J.,Dickson, C.F.,Weidenhausen, J.,Smyly, S.,Yang, J.C.,Maslen, S.L.,Sinning, I.,Neuhaus, D.,Clift, D.,James, L.C. Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nat Commun 2023 14 2160 2160