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Oxid Med Cell Longev 2017 2017 8940321 8940321 5LCL 28444956 STRUCTURE OF the RAD14 DNA-binding domain IN COMPLEX WITH C8-aminofluorene- GUANINE CONTAINING DNA 2016-06-22 2017-05-10 Ebert, C.,Simon, N.,Schneider, S.,Carell, T. Structural Insights into the Recognition of N(2) -Aryl- and C8-Aryl DNA Lesions by the Repair Protein XPA/Rad14. Chembiochem 2017 18 1379 1382 5NCS 28512127 Structure of the native serpin-type proteinase inhibitor, miropin. 2017-03-06 2017-05-24 Goulas, T.,Ksiazek, M.,Garcia-Ferrer, I.,Sochaj-Gregorczyk, A.M.,Waligorska, I.,Wasylewski, M.,Potempa, J.,Gomis-Ruth, F.X. A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem. 2017 292 10883 10898 5L6H 28578874 Uba1 in complex with Ub-ABPA3 covalent adduct 2016-05-30 2017-06-14 Misra, M.,Kuhn, M.,Lobel, M.,An, H.,Statsyuk, A.V.,Sotriffer, C.,Schindelin, H. Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure 2017 25 1120 0 5MWN 28650463 Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27 2017-01-18 2017-06-28 Nguyen, V.S.,Logger, L.,Spinelli, S.,Legrand, P.,Huyen Pham, T.T.,Nhung Trinh, T.T.,Cherrak, Y.,Zoued, A.,Desmyter, A.,Durand, E.,Roussel, A.,Kellenberger, C.,Cascales, E.,Cambillau, C. Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol 2017 2 17103 17103 5LRP 28777079 Mopeia Virus Exonuclease domain complexed with Magnesium 2016-08-19 2017-07-05 Yekwa, E.,Khourieh, J.,Canard, B.,Papageorgiou, N.,Ferron, F. Activity inhibition and crystal polymorphism induced by active-site metal swapping. 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PLoS Pathog. 2017 13 0 0 5O0Q 29095159 Deglycosylated Nogo Receptor with native disulfide structure 2017-05-16 2017-10-18 Pronker, M.F.,Tas, R.P.,Vlieg, H.C.,Janssen, B.J.C. Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction. Acta Crystallogr D Struct Biol 2017 73 860 876 5NZB 29035299 A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2 2017-05-12 2017-10-25 Soh, W.T.,Briza, P.,Dall, E.,Asam, C.,Schubert, M.,Huber, S.,Aglas, L.,Bohle, B.,Ferreira, F.,Brandstetter, H. Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S. Int J Mol Sci 2017 18 0 0 5NZC 29035299 A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2 2017-05-12 2017-10-25 Soh, W.T.,Briza, P.,Dall, E.,Asam, C.,Schubert, M.,Huber, S.,Aglas, L.,Bohle, B.,Ferreira, F.,Brandstetter, H. 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Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun 2017 8 2070 2070 5NJ2 29087696 Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate 2017-03-27 2017-11-15 Elings, W.,Tassoni, R.,van der Schoot, S.A.,Luu, W.,Kynast, J.P.,Dai, L.,Blok, A.J.,Timmer, M.,Florea, B.I.,Pannu, N.S.,Ubbink, M. Phosphate Promotes the Recovery of Mycobacterium tuberculosis beta-Lactamase from Clavulanic Acid Inhibition. Biochemistry 2017 56 6257 6267 5NWI 28970335 14-3-3c in complex with CPP 2017-05-06 2017-11-22 Saponaro, A.,Porro, A.,Chaves-Sanjuan, A.,Nardini, M.,Rauh, O.,Thiel, G.,Moroni, A. Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell 2017 29 2570 2580 5NWJ 28970335 14-3-3c in complex with CPP7 2017-05-06 2017-11-22 Saponaro, A.,Porro, A.,Chaves-Sanjuan, A.,Nardini, M.,Rauh, O.,Thiel, G.,Moroni, A. 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Nat Commun 2017 8 1529 1529 6FOE 29412660 BaxB01 Fab fragment 2018-02-07 2018-02-28 Schinagl, A.,Kerschbaumer, R.J.,Sabarth, N.,Douillard, P.,Scholz, P.,Voelkel, D.,Hollerweger, J.C.,Goettig, P.,Brandstetter, H.,Scheiflinger, F.,Thiele, M. Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch. Biochemistry 2018 57 1523 1532 5X9I Unique Choloylglycine Hydrolase(CGH) member Mutant (C1S) from Shewanella loihica PV-4 2017-03-07 2018-03-07 Philem, P.,Yadav, Y.,Prabune, A.A.,Ramasamy, S. Unique Choloylglycine Hydrolase(CGH) member from Shewanella loihica PV-4 To Be Published 0 0 0 0 5NN0 29227101 Crystal structure of huBChE with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-N-(2-(dimethylamino)ethyl)-2-naphthamide. 2017-04-07 2018-03-14 Kosak, U.,Brus, B.,Knez, D.,Zakelj, S.,Trontelj, J.,Pislar, A.,Sink, R.,Jukic, M.,Zivin, M.,Podkowa, A.,Nachon, F.,Brazzolotto, X.,Stojan, J.,Kos, J.,Coquelle, N.,Salat, K.,Colletier, J.P.,Gobec, S. 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Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci 2023 0 0 0 6Z0F 36154281 Crystal structure of the membrane pseudokinase YukC/EssB from Bacillus subtilis T7SS 2020-05-08 2021-05-19 Tassinari, M.,Doan, T.,Bellinzoni, M.,Chabalier, M.,Ben-Assaya, M.,Martinez, M.,Gaday, Q.,Alzari, P.M.,Cascales, E.,Fronzes, R.,Gubellini, F. The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB. Mbio 2022 13 0 0 6ZP3 33950676 Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 2-Methylindole-3-acetic acid 2020-07-08 2021-05-19 Fata, F.,Silvestri, I.,Ardini, M.,Ippoliti, R.,Di Leandro, L.,Demitri, N.,Polentarutti, M.,Di Matteo, A.,Lyu, H.,Thatcher, G.R.J.,Petukhov, P.A.,Williams, D.L.,Angelucci, F. Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. 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Exploring molecular determinants of polysaccharide lyase family 6-1 enzyme activity. Glycobiology 2021 31 1557 1570 7OSY 34360555 Human Prolyl-tRNA Synthetase in Complex with L-proline 2021-06-09 2021-07-28 Pang, L.,Weeks, S.D.,Juhas, M.,Strelkov, S.V.,Zitko, J.,Van Aerschot, A. Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies. Int J Mol Sci 2021 22 0 0 7OT1 34360555 Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 3c 2021-06-09 2021-07-28 Pang, L.,Weeks, S.D.,Juhas, M.,Strelkov, S.V.,Zitko, J.,Van Aerschot, A. Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies. 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Biomolecules 2022 12 0 0 7PSG 35254130 Structure of the ligand binding domain of the PacA (ECA2226) chemoreceptor of Pectobacterium atrosepticum SCRI1043 in complex with betaine. 2021-09-23 2022-05-11 Matilla, M.A.,Velando, F.,Tajuelo, A.,Martin-Mora, D.,Xu, W.,Sourjik, V.,Gavira, J.A.,Krell, T. Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine. Mbio 2022 13 0 0 7TNG Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) 2022-01-21 2022-05-11 Guarino, S.R.,Palamini, M.,Capillo, M.C.,Forneris, F. Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1) Acta Crystallogr.,Sect.F 2022 78 185 192 8A3O 37267906 Structure of human Fy-4 2022-06-08 2022-06-29 Quentin, D.,Schuhmacher, J.S.,Klink, B.U.,Lauer, J.,Shaikh, T.R.,Huis In 't Veld, P.J.,Welp, L.M.,Urlaub, H.,Zerial, M.,Raunser, S. Structural basis of mRNA binding by the human FERRY Rab5 effector complex. Mol.Cell 2023 83 1856 0 8A3P 37267906 Structure of human Fy-5. 2022-06-08 2022-06-29 Quentin, D.,Schuhmacher, J.S.,Klink, B.U.,Lauer, J.,Shaikh, T.R.,Huis In 't Veld, P.J.,Welp, L.M.,Urlaub, H.,Zerial, M.,Raunser, S. Structural basis of mRNA binding by the human FERRY Rab5 effector complex. Mol.Cell 2023 83 1856 0 8A0O 36032685 Crystal structure of poplar glutathione transferase U20 in complex with galangin 2022-05-29 2022-07-20 Sylvestre-Gonon, E.,Morette, L.,Viloria, M.,Mathiot, S.,Boutilliat, A.,Favier, F.,Rouhier, N.,Didierjean, C.,Hecker, A. Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. Front Mol Biosci 2022 9 958586 958586 8A0R 36032685 Crystal structure of poplar glutathione transferase U20 in complex with pinocembrin 2022-05-30 2022-07-20 Sylvestre-Gonon, E.,Morette, L.,Viloria, M.,Mathiot, S.,Boutilliat, A.,Favier, F.,Rouhier, N.,Didierjean, C.,Hecker, A. Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. Front Mol Biosci 2022 9 958586 958586 7P5O Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate 2021-07-14 2022-07-27 Yan, K.,Stanley, M.,Kowalski, B.,Raimi, O.G.,Ferenbach, A.T.,Wei, P.Z.,Yuan, H.,Fang, W.,van Aalten, D.M.F. Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus To Be Published 0 0 0 0 7P8O Crystal structure of D-aminoacid transaminase from Haliscomenobacter hydrossis in its intermediate form 2021-07-23 2022-08-03 Matyuta, I.O.,Boyko, K.M.,Bakunova, A.K.,Nikolaeva, A.Y.,Rakitina, T.V.,Bezsudnova, E.Y.,Popov, V.O. Crystal structure of D-aminoacid transaminase from Haliscomenobacter hydrossis in its apo form To Be Published 0 0 0 0 7QYQ 35950185 Crystal structure of a DyP-type peroxidase from Pseudomonas putida 2022-01-28 2022-08-03 Borges, P.T.,Silva, D.,Silva, T.F.D.,Brissos, V.,Canellas, M.,Lucas, M.F.,Masgrau, L.,Melo, E.P.,Machuqueiro, M.,Frazao, C.,Martins, L.O. Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase. Comput Struct Biotechnol J 2022 20 3899 3910 7S24 36289233 Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 2021-09-03 2022-08-10 Winkelmann, I.,Uzdavinys, P.,Kenney, I.M.,Brock, J.,Meier, P.F.,Wagner, L.M.,Gabriel, F.,Jung, S.,Matsuoka, R.,von Ballmoos, C.,Beckstein, O.,Drew, D. Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing. Nat Commun 2022 13 6383 6383 7AMB 35959919 Crystal structure of rsFolder2 in its fluorescent on-state 2020-10-08 2022-08-24 Adam, V.,Hadjidemetriou, K.,Jensen, N.,Shoeman, R.L.,Woodhouse, J.,Aquila, A.,Banneville, A.S.,Barends, T.R.M.,Bezchastnov, V.,Boutet, S.,Byrdin, M.,Cammarata, M.,Carbajo, S.,Eleni Christou, N.,Coquelle, N.,De la Mora, E.,El Khatib, M.,Moreno Chicano, T.,Bruce Doak, R.,Fieschi, F.,Foucar, L.,Glushonkov, O.,Gorel, A.,Grunbein, M.L.,Hilpert, M.,Hunter, M.,Kloos, M.,Koglin, J.E.,Lane, T.J.,Liang, M.,Mantovanelli, A.,Nass, K.,Nass Kovacs, G.,Owada, S.,Roome, C.M.,Schiro, G.,Seaberg, M.,Stricker, M.,Thepaut, M.,Tono, K.,Ueda, K.,Uriarte, L.M.,You, D.,Zala, N.,Domratcheva, T.,Jakobs, S.,Sliwa, M.,Schlichting, I.,Colletier, J.P.,Bourgeois, D.,Weik, M. Rational Control of Off-State Heterogeneity in a Photoswitchable Fluorescent Protein Provides Switching Contrast Enhancement. Chemphyschem 2022 23 0 0 7AMF 35959919 Crystal structure of rsFolder2 in its non-fluorescent off-state 2020-10-08 2022-08-24 Adam, V.,Hadjidemetriou, K.,Jensen, N.,Shoeman, R.L.,Woodhouse, J.,Aquila, A.,Banneville, A.S.,Barends, T.R.M.,Bezchastnov, V.,Boutet, S.,Byrdin, M.,Cammarata, M.,Carbajo, S.,Eleni Christou, N.,Coquelle, N.,De la Mora, E.,El Khatib, M.,Moreno Chicano, T.,Bruce Doak, R.,Fieschi, F.,Foucar, L.,Glushonkov, O.,Gorel, A.,Grunbein, M.L.,Hilpert, M.,Hunter, M.,Kloos, M.,Koglin, J.E.,Lane, T.J.,Liang, M.,Mantovanelli, A.,Nass, K.,Nass Kovacs, G.,Owada, S.,Roome, C.M.,Schiro, G.,Seaberg, M.,Stricker, M.,Thepaut, M.,Tono, K.,Ueda, K.,Uriarte, L.M.,You, D.,Zala, N.,Domratcheva, T.,Jakobs, S.,Sliwa, M.,Schlichting, I.,Colletier, J.P.,Bourgeois, D.,Weik, M. Rational Control of Off-State Heterogeneity in a Photoswitchable Fluorescent Protein Provides Switching Contrast Enhancement. Chemphyschem 2022 23 0 0 7PGA 36874276 Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK 2021-08-13 2022-08-24 Dinis, P.,Tirkkonen, H.,Wandi, B.N.,Siitonen, V.,Niemi, J.,Grocholski, T.,Metsa-Ketela, M. Evolution-inspired engineering of anthracycline methyltransferases. Pnas Nexus 2023 2 0 0 7PGJ 36874276 Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-decarboxylate TamK and 10-hydroxylase RdmB, together with a single point mutation F297G 2021-08-14 2022-08-24 Dinis, P.,Tirkkonen, H.,Wandi, B.N.,Siitonen, V.,Niemi, J.,Grocholski, T.,Metsa-Ketela, M. Evolution-inspired engineering of anthracycline methyltransferases. Pnas Nexus 2023 2 0 0 7NU4 36038645 Crystal Structure of Neisseria gonorrhoeae LeuRS 2021-03-11 2022-08-31 Pang, L.,Zanki, V.,Strelkov, S.V.,Van Aerschot, A.,Gruic-Sovulj, I.,Weeks, S.D. Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol 2022 5 883 883 7NU7 36038645 Crystal Structure of Neisseria gonorrhoeae LeuRS in Complex with ATP in Conformation 2 2021-03-11 2022-08-31 Pang, L.,Zanki, V.,Strelkov, S.V.,Van Aerschot, A.,Gruic-Sovulj, I.,Weeks, S.D. Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol 2022 5 883 883 7NU9 36038645 Crystal Structure of Neisseria gonorrhoeae LeuRS in Complex with ATP and L-leucinol 2021-03-11 2022-08-31 Pang, L.,Zanki, V.,Strelkov, S.V.,Van Aerschot, A.,Gruic-Sovulj, I.,Weeks, S.D. Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol 2022 5 883 883 7PVR Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E-G92N-Y93N-N94T-H95E mutant in the space group P41 2021-10-05 2022-09-14 Camara-Artigas, A.,Salinas Garcia, M.C. The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published 0 0 0 0 7PVT Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12 2021-10-05 2022-09-14 Camara-Artigas, A.,Salinas Garcia, M.C. Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12 To be published 0 0 0 0 7PVX Crystal structure of the c-Src SH3 domain mutant E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H in complex with the synthetic peptide VSL12 2021-10-05 2022-09-14 Camara-Artigas, A.,Salinas Garcia, M.C. Crystal structure of the c-Src SH3 domain mutants of the specificity region in complex with polyproline peptides To be published 0 0 0 0 7PW0 Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant 2021-10-05 2022-09-14 Camara-Artigas, A.,Salinas Garcia, M.C. The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published 0 0 0 0 8AE4 36116553 Crystal structure of human legumain in complex with Clitocypin 2 2022-07-12 2022-09-28 Elamin, T.,Santos, N.P.,Briza, P.,Brandstetter, H.,Dall, E. Structural and functional studies of legumain-mycocypin complexes revealed a competitive, exosite-regulated mode of interaction. J.Biol.Chem. 2022 298 102502 102502 8AE5 36116553 Crystal structure of human legumain in complex with macrocypin 1a 2022-07-12 2022-09-28 Elamin, T.,Santos, N.P.,Briza, P.,Brandstetter, H.,Dall, E. Structural and functional studies of legumain-mycocypin complexes revealed a competitive, exosite-regulated mode of interaction. J.Biol.Chem. 2022 298 102502 102502 7SKN De novo synthetic protein DIG8-CC (tetragonal space group) 2021-10-21 2022-10-12 Chidyausiku, T.M.,Mendes, S.R.,Klima, J.C.,Nadal, M.,Eckhard, U.,Roel-Touris, J.,Houliston, S.,Guevara, T.,Haddox, H.K.,Moyer, A.,Arrowsmith, C.H.,Gomis-Ruth, F.X.,Baker, D.,Marcos, E. De novo design of immunoglobulin-like domains Nat Commun 2022 13 5661 0 7ZTU 36395947 Crystal structure of the carotenoid-binding protein domain from silkworm Bombyx mori (BmCBP) in the apoform, D162L mutant 2022-05-11 2022-10-26 Sluchanko, N.N.,Slonimskiy, Y.B.,Egorkin, N.A.,Varfolomeeva, L.A.,Faletrov, Y.V.,Moysenovich, A.M.,Parshina, E.Y.,Friedrich, T.,Maksimov, E.G.,Boyko, K.M.,Popov, V.O. Silkworm carotenoprotein as an efficient carotenoid extractor, solubilizer and transporter. Int.J.Biol.Macromol. 2022 223 1381 1393 8A47 36528711 IdeS in complex with IgG1 Fc 2022-06-10 2022-11-30 Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M. Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS. Nat Commun 2022 13 7801 7801 8A48 36528711 Less crystallisable"" IgG1 Fc fragment (E382S variant) 2022-06-10 2022-11-30 Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M. Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS. Nat Commun 2022 13 7801 7801 7QEK 36602305 Structure of the ligand binding domain of the antibiotic biosynthesis regulator AdmX from the rhizobacterium Serratia plymuthica A153 bound to the auxin indole-3-piruvic acid (IPA). 2021-12-03 2022-12-14 Gavira, J.A.,Rico-Jimenez, M.,Ortega, A.,Petukhova, N.V.,Bug, D.S.,Castellvi, A.,Porozov, Y.B.,Zhulin, I.B.,Krell, T.,Matilla, M.A. Emergence of an Auxin Sensing Domain in Plant-Associated Bacteria. Mbio 2023 14 0 0 7OWQ 36181773 HsNMT1 in complex with both MyrCoA and peptide N-Methylated-GNCFSKPR 2021-06-18 2022-12-21 Riviere, F.,Dian, C.,Dutheil, R.F.,Monassa, P.,Giglione, C.,Meinnel, T. Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. J.Mol.Biol. 2022 434 167843 167843 7OX1 Fab 7D6: hIL-9 complex 2021-06-22 2022-12-28 De Vos, T.,Godar, M.,Bick, F.,Papageorgiou, A.C.,Evangelidis, T.,Markovic, I.,Mortier, E.,Dumoutier, L.,Tripsianes, K.,Blanchetot, C.,Savvides, S.N. Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv 2022 0 0 0 8AT8 36479958 Structure of coproporphyrin III-LmCpfC 2022-08-22 2022-12-28 Dali, A.,Gabler, T.,Sebastiani, F.,Destinger, A.,Furtmuller, P.G.,Pfanzagl, V.,Becucci, M.,Smulevich, G.,Hofbauer, S. Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation. Protein Sci. 2023 32 0 0 8B7W 36499233 Complex IL-17A/anti-IL-17A-76 2022-10-03 2022-12-28 Kostareva, O.,Svoeglazova, A.,Kolyadenko, I.,Nikulin, A.,Evdokimov, S.,Dzhus, U.,Gabdulkhakov, A.,Tishchenko, S. Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V H H Domain. Int J Mol Sci 2022 23 0 0 7ZZ9 36455355 Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative 2022-05-25 2023-01-11 Clement, D.A.,Gelin, M.,Leseigneur, C.,Huteau, V.,Mondange, L.,Pons, J.L.,Dussurget, O.,Lionne, C.,Labesse, G.,Pochet, S. Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria. Eur.J.Med.Chem. 2023 246 114941 114941 7ZZA 36455355 Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative 2022-05-25 2023-01-11 Clement, D.A.,Gelin, M.,Leseigneur, C.,Huteau, V.,Mondange, L.,Pons, J.L.,Dussurget, O.,Lionne, C.,Labesse, G.,Pochet, S. Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria. Eur.J.Med.Chem. 2023 246 114941 114941 8B47 36455355 Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a cyclic di-adenosine derivative 2022-09-20 2023-01-11 Clement, D.A.,Gelin, M.,Leseigneur, C.,Huteau, V.,Mondange, L.,Pons, J.L.,Dussurget, O.,Lionne, C.,Labesse, G.,Pochet, S. Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria. Eur.J.Med.Chem. 2023 246 114941 114941 8BPN The structure of thiocyanate dehydrogenase mutant form with Phe 436 replaced by Gln from Thioalkalivibrio paradoxus 2023-01-09 2023-01-18 Varfolomeeva, L.A.,Solovieva, A.Y.,Shipkov, N.S.,Kulikova, O.G.,Dergousova, N.I.,Rakitina, T.V.,Boyko, K.M.,Tikhonova, T.V.,Popov, V.O. Probing the Role of a Conserved Phenylalanine in the Active Site of Thiocyanate Dehydrogenase Crystals 2022 12 0 0 8A0H 36165868 Crystal structure of the E25A mutant of the Orange Carotenoid Protein X from Gloeobacter kilaueensis JS1 complexed with echinenone 2022-05-27 2023-02-01 Slonimskiy, Y.B.,Zupnik, A.O.,Varfolomeeva, L.A.,Boyko, K.M.,Maksimov, E.G.,Sluchanko, N.N. A primordial Orange Carotenoid Protein: Structure, photoswitching activity and evolutionary aspects. Int.J.Biol.Macromol. 2022 222 167 180 7QZK Crystal structure of mouse CNPase catalytic domain, V318I mutant 2022-01-31 2023-02-15 Markusson, S.,Kursula, P. Crystal structure of mouse CNPase catalytic domain, V318I mutant To Be Published 0 0 0 0 7QZS Crystal structure of mouse CNPase catalytic domain, G324D mutant 2022-01-31 2023-02-15 Markusson, S.,Kursula, P. Crystal structure of mouse CNPase catalytic domain, G324D mutant To Be Published 0 0 0 0 8A8I 36846821 Xenobiotic reductase A from Pseudomonas putida in complex with ethyl (Z)-2-(hydroxyimino)-3-oxobutanoate 2022-06-23 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8AU8 36846821 Xenobiotic reductase A from P. putida in complex with ethyl (Z)-2-(hydroxyimino)-3-oxopentanoate 2022-08-25 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8AUJ 36846821 OPR3 Y190F variant in complex with ethyl (Z)-2-(hydroxyimino)-3-oxobutanoate 2022-08-25 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8AUN 36846821 OPR3 Y370F variant in complex with ethyl (Z)-2-(hydroxyimino)-3-oxobutanoate 2022-08-25 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8AUO 36846821 OPR3 Y370F variant in complex with 2-methoxyethyl (Z)-2-(hydroxyimino)-3-oxobutanoate 2022-08-25 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8AUQ 36846821 OPR3 Y370F variant in complex with ethyl (Z)-2-(hydroxyimino)-3-oxopentanoate 2022-08-25 2023-03-01 Breukelaar, W.B.,Polidori, N.,Singh, A.,Daniel, B.,Glueck, S.M.,Gruber, K.,Kroutil, W. Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis 2023 13 2610 2618 8CIK Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution 2023-02-09 2023-03-08 Belenkaya, S.V.,Diusenova, S.E.,Shevtsov, M.B.,Borshchevskiy, V.I.,Arkhipov, S.G.,Kolybalov, D.S.,Volosnikova, E.A.,Elchaninov, V.V.,Shcherbakov, D.N. Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution To Be Published 0 0 0 0 7ZE9 37066045 Structure of an AA16 LPMO-like protein 2022-03-30 2023-03-15 Sun, P.,Huang, Z.,Banerjee, S.,Kadowaki, M.A.S.,Veersma, R.J.,Magri, S.,Hilgers, R.,Muderspach, S.J.,Laurent, C.V.F.P.,Ludwig, R.,Cannella, D.,Lo Leggio, L.,van Berkel, W.J.H.,Kabel, M.A. AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila. Acs Catalysis 2023 13 4454 4467 8A2V 36381146 Room temperature structure of the ground state of AtPhot2LOV2 in space group P43212 2022-06-06 2023-03-29 Aumonier, S.,Engilberge, S.,Caramello, N.,von Stetten, D.,Gotthard, G.,Leonard, G.A.,Mueller-Dieckmann, C.,Royant, A. Slow protein dynamics probed by time-resolved oscillation crystallography at room temperature. Iucrj 2022 9 756 767 8A2W 36381146 Room temperature structure of the ground state of AtPhot2LOV2 in space group P212121, as recovered 1620 seconds after light irradiation 2022-06-06 2023-03-29 Aumonier, S.,Engilberge, S.,Caramello, N.,von Stetten, D.,Gotthard, G.,Leonard, G.A.,Mueller-Dieckmann, C.,Royant, A. Slow protein dynamics probed by time-resolved oscillation crystallography at room temperature. Iucrj 2022 9 756 767 8A4E 36381146 Room temperature structure of AtPhot2LOV2 in a photostationary equilibrium 2022-06-10 2023-03-29 Aumonier, S.,Engilberge, S.,Caramello, N.,von Stetten, D.,Gotthard, G.,Leonard, G.A.,Mueller-Dieckmann, C.,Royant, A. Slow protein dynamics probed by time-resolved oscillation crystallography at room temperature. Iucrj 2022 9 756 767 8AFJ tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock 2022-07-18 2023-03-29 van der Linden, P.,Engilberge, S.,Atta, M.,Carpentier, P. tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock To Be Published 0 0 0 0 8C6O 37047842 Crystal Structure of H64F obelin mutant from Obelia longissima at 2.2 Angstrom resolution 2023-01-12 2023-03-29 Natashin, P.V.,Burakova, L.P.,Kovaleva, M.I.,Shevtsov, M.B.,Dmitrieva, D.A.,Eremeeva, E.V.,Markova, S.V.,Mishin, A.V.,Borshchevskiy, V.I.,Vysotski, E.S. The Role of Tyr-His-Trp Triad and Water Molecule Near the N1-Atom of 2-Hydroperoxycoelenterazine in Bioluminescence of Hydromedusan Photoproteins: Structural and Mutagenesis Study. Int J Mol Sci 2023 24 0 0 7ZNP Structure of AmedSP 2022-04-21 2023-05-10 Fredslund, F.,Teze, D.,Welner, D.H. Structure of AmedSP To Be Published 0 0 0 0 7R2M SYNJ2BP complex with a synthetic Vangl2 peptide (9mer). 2022-02-04 2023-05-17 Carrasco, K.,Cousido Siah, A.,Gogl, G.,Betzi, S.,McEwen, A.,Kostmann, C.,Trave, G. SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published 0 0 0 0 8OSI 37163937 Genetically encoded green ratiometric calcium indicator FNCaMP in calcium-bound state 2023-04-19 2023-05-24 Subach, O.M.,Varfolomeeva, L.,Vlaskina, A.V.,Agapova, Y.K.,Nikolaeva, A.Y.,Piatkevich, K.D.,Patrushev, M.V.,Boyko, K.M.,Subach, F.V. FNCaMP, ratiometric green calcium indicator based on mNeonGreen protein. Biochem.Biophys.Res.Commun. 2023 665 169 177 8AM1 36193860 Human butyrylcholinesterase in complex with zinc and N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium 2022-08-02 2023-06-14 Nachon, F.,Brazzolotto, X.,Dias, J.,Courageux, C.,Drozdz, W.,Cao, X.Y.,Stefankiewicz, A.R.,Lehn, J.M. Grid-Type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions. Chembiochem 2022 23 0 0 8CP5 37302552 Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and Sulphate 2023-03-01 2023-07-12 Rotilio, L.,Boverio, A.,Nguyen, Q.T.,Mannucci, B.,Fraaije, M.W.,Mattevi, A. A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center. J.Biol.Chem. 2023 299 104904 104904 8AHA 37389576 rsEGFP2 photoswitched to its off-state at 100K 2022-07-21 2023-07-19 Mantovanelli, A.M.R.,Glushonkov, O.,Adam, V.,Wulffele, J.,Thedie, D.,Byrdin, M.,Gregor, I.,Nevskyi, O.,Enderlein, J.,Bourgeois, D. Photophysical Studies at Cryogenic Temperature Reveal a Novel Photoswitching Mechanism of rsEGFP2. J.Am.Chem.Soc. 2023 145 14636 14646 8ADX Structure of the Reconstructed Ancestor of Phenolic Acid Decarboxylase AncPAD55 2022-07-12 2023-08-02 Myrtollari, K.,Kracher, D.,Calderini, E.,Mokos, D.,Schruefer, A.,Wirnsberger, G.,Gruber, K.,Daniel, B.,Kourist, R. Reconstructed ancestral sequences of bacterial phenolic acid decarboxylase show increased thermostability To Be Published 0 0 0 0 8BY5 37758951 C. elegans TOFU-6 eTUDOR TOFU-1 peptide complex 2022-12-12 2023-08-16 Podvalnaya, N.,Bronkhorst, A.W.,Lichtenberger, R.,Hellmann, S.,Nischwitz, E.,Falk, T.,Karaulanov, E.,Butter, F.,Falk, S.,Ketting, R.F. piRNA processing by a trimeric Schlafen-domain nuclease. Nature 2023 622 402 409 8P5S 37563123 Crystal structure of the homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum 2023-05-24 2023-08-16 Yang, L.,Wagner, T.,Mechaly, A.,Boyko, A.,Bruch, E.M.,Megrian, D.,Gubellini, F.,Alzari, P.M.,Bellinzoni, M. High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase. Nat Commun 2023 14 4851 4851 8GT0 Structure of falcipain and human Stefin A complex 2022-09-07 2023-09-13 Chakraborty, S.,Biswas, S. Structure of falcipain and human Stefin A complex To Be Published 0 0 0 0 8GT7 Structure of falcipain and human Stefin A mutant complex 2022-09-07 2023-09-13 Chakraborty, S.,Biswas, S. Structure of falcipain and human Stefin A complex To Be Published 0 0 0 0 8IBP Crystal structure of Mycobacterium tuberculosis R21K ClpC1 N-terminal domain in complex with Lassomycin 2023-02-10 2023-09-20 Jagdev, M.K.,Tompa, D.R.,Ling, L.L.,Peoples, A.J.,Dandapat, J.,Mohapatra, C.,Lewis, K.,Vasudevan, D. Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin Int.J.Biol.Macromol. 2023 253 126771 0 8B2Y Structure of the weakly red fluorescent protein csiFP4 from Clytia simplex 2022-09-15 2023-09-27 Depernet, H.,Engilberge, S.,Lambert, G.,Gotthard, G.,Shaner, N.,Royant, A. Structure of the weakly red fluorescent protein csiFP4 from Clytia simplex To Be Published 0 0 0 0 8CM7 37985883 W-formate dehydrogenase M405A from Desulfovibrio vulgaris 2023-02-17 2023-09-27 Oliveira, A.R.,Mota, C.,Vilela-Alves, G.,Manuel, R.R.,Pedrosa, N.,Fourmond, V.,Klymanska, K.,Leger, C.,Guigliarelli, B.,Romao, M.J.,Cardoso Pereira, I.A. An allosteric redox switch involved in oxygen protection in a CO 2 reductase. Nat.Chem.Biol. 2024 20 111 119 8BV9 37804591 Acylphosphatase from E. coli 2023-01-18 2023-10-18 Martinez-Rodriguez, S.,Camara-Artigas, A.,Gavira, J.A. First 3-D structural evidence of a native-like intertwined dimer in the acylphosphatase family. Biochem.Biophys.Res.Commun. 2023 682 85 90 8OXW 37798283 Transglutaminase 3 in complex with DH patient-derived Fab DH63-B02 2023-05-02 2023-10-18 Heggelund, J.E.,Das, S.,Stamnaes, J.,Iversen, R.,Sollid, L.M. Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun 2023 14 6216 6216 8B67 37819038 The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site 2022-09-26 2023-10-25 Parkash, V.,Kulkarni, Y.,Bylund, G.O.,Osterman, P.,Kamerlin, S.C.L.,Johansson, E. A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res. 2023 0 0 0 8B77 37819038 The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site 2022-09-29 2023-10-25 Parkash, V.,Kulkarni, Y.,Bylund, G.O.,Osterman, P.,Kamerlin, S.C.L.,Johansson, E. A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res. 2023 0 0 0 8B7E 37819038 The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site 2022-09-29 2023-10-25 Parkash, V.,Kulkarni, Y.,Bylund, G.O.,Osterman, P.,Kamerlin, S.C.L.,Johansson, E. A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res. 2023 0 0 0 8B9X 37988244 Chimeric protein of human UFM1 E3 ligase, UFL1, and DDRGK1 2022-10-10 2023-10-25 Banerjee, S.,Varga, J.K.,Kumar, M.,Zoltsman, G.,Rotem-Bamberger, S.,Cohen-Kfir, E.,Isupov, M.N.,Rosenzweig, R.,Schueler-Furman, O.,Wiener, R. Structural study of UFL1-UFC1 interaction uncovers the role of UFL1 N-terminal helix in ufmylation. Embo Rep. 2023 24 0 0 8AMS Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin 2022-08-04 2023-11-15 Perez-Borrajero, C.,Hennig, J. Structural and biophysical studies of TRIM2 and TRIM3 To Be Published 0 0 0 0 8OWZ 37902787 Crystal structure of human Sirt2 in complex with a triazole-based SirReal 2023-04-28 2023-11-15 Sinatra, L.,Vogelmann, A.,Friedrich, F.,Tararina, M.A.,Neuwirt, E.,Colcerasa, A.,Konig, P.,Toy, L.,Yesiloglu, T.Z.,Hilscher, S.,Gaitzsch, L.,Papenkordt, N.,Zhai, S.,Zhang, L.,Romier, C.,Einsle, O.,Sippl, W.,Schutkowski, M.,Gross, O.,Bendas, G.,Christianson, D.W.,Hansen, F.K.,Jung, M.,Schiedel, M. Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem. 2023 66 14787 14814 8C5X 36837657 Double mutant A(L37)C/S(L99)C structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV 2023-01-10 2023-11-22 Selikhanov, G.,Atamas, A.,Yukhimchuk, D.,Fufina, T.,Vasilieva, L.,Gabdulkhakov, A. Stabilization of Cereibacter sphaeroides Photosynthetic Reaction Center by the Introduction of Disulfide Bonds. Membranes (Basel) 2023 13 0 0 8C7C 36837657 Double mutant V(M84)C/A(L278)C structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV 2023-01-14 2023-11-22 Selikhanov, G.,Atamas, A.,Yukhimchuk, D.,Fufina, T.,Vasilieva, L.,Gabdulkhakov, A. Stabilization of Cereibacter sphaeroides Photosynthetic Reaction Center by the Introduction of Disulfide Bonds. Membranes (Basel) 2023 13 0 0 8C88 36837657 Double mutant G(M19)C/T(L214)C structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV 2023-01-19 2023-11-22 Selikhanov, G.,Atamas, A.,Yukhimchuk, D.,Fufina, T.,Vasilieva, L.,Gabdulkhakov, A. Stabilization of Cereibacter sphaeroides Photosynthetic Reaction Center by the Introduction of Disulfide Bonds. Membranes (Basel) 2023 13 0 0 8Q77 STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE BISUBSTRATE INHIBITOR ARC-780 2023-08-15 2023-12-06 Werner, C.,Lindenblatt, D.,Viht, K.,Uri, A.,Niefind, K. Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool Kinases Phosphatases 2023 0 0 0 8BVA Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_114-126 2022-12-02 2023-12-13 Cura, V.,Troffer-Charlier, N.,Marechal, N.,Bonnefond, L.,Cavarelli, J. Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_114-126 To Be Published 0 0 0 0 8PQD 38167404 c-KIT kinase domain in complex with avapritinib derivative 10 2023-07-11 2023-12-27 Teuber, A.,Schulz, T.,Fletcher, B.S.,Gontla, R.,Muhlenberg, T.,Zischinsky, M.L.,Niggenaber, J.,Weisner, J.,Kleinbolting, S.B.,Lategahn, J.,Sievers, S.,Muller, M.P.,Bauer, S.,Rauh, D. Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nat Commun 2024 15 63 63 8C14 Aurora A kinase in complex with TPX2-inhibitor 9 2022-12-20 2024-01-10 Stockwell, S.,Scott, D.,Fischer, G.,Guarino Almeida, E.,Rooney, T.,Feng, J.,Moschetti, T.,Dagostin, C.,Alcaide-Lopez, A.,Rocaboy, M.,Srinivasan, R.,Asteian, A.,Alza, E.,Blaszczyk, B.,Wang, X.,Rossmann, M.,Perrior, T.,Blundell, T.L.,Spring, D.R.,McKenzie, G.,Abell, C.,Skidmore, J.,Venkitaraman, A.,Hyvonen, M. Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agent To Be Published 0 0 0 0 8C1D Aurora A kinase in complex with TPX2-inhibitor 9 2022-12-20 2024-01-10 Stockwell, S.,Scott, D.,Fischer, G.,Guarino Almeida, E.,Rooney, T.,Feng, J.,Moschetti, T.,Dagostin, C.,Alcaide-Lopez, A.,Rocaboy, M.,Srinivasan, R.,Asteian, A.,Alza, E.,Blaszczyk, B.,Wang, X.,Rossmann, M.,Perrior, T.,Blundell, T.L.,Spring, D.R.,McKenzie, G.,Abell, C.,Skidmore, J.,Venkitaraman, A.,Hyvonen, M. Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agent To Be Published 0 0 0 0 8C1F Aurora A kinase in complex with TPX2-inhibitor 6 2022-12-20 2024-01-10 Stockwell, S.,Scott, D.,Fischer, G.,Guarino Almeida, E.,Rooney, T.,Feng, J.,Moschetti, T.,Dagostin, C.,Alcaide-Lopez, A.,Rocaboy, M.,Srinivasan, R.,Asteian, A.,Alza, E.,Blaszczyk, B.,Wang, X.,Rossmann, M.,Perrior, T.,Blundell, T.L.,Spring, D.R.,McKenzie, G.,Abell, C.,Skidmore, J.,Venkitaraman, A.,Hyvonen, M. Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agent To Be Published 0 0 0 0 7YP8 Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Leucyl-sulfamoyl 3-deazaadenosine 2022-08-02 2024-02-07 Pang, L.,De Graef, S.,Zhang, B.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. The essential role of a structured water in base recognition of Class II aminoacyl-tRNA synthetases To be published 0 0 0 0 8CCT Crystal structure of the human PXR ligand-binding domain in complex with 2,2'-dichloro bisphenol A 2023-01-27 2024-02-07 Derosa, Q.,Grimaldi, M.,Carivenc, C.,Boulahtouf, A.,Bourguet, W.,Balaguer, P. Crystal structure of the hPXR-LBD in complex with 2,2'-dichloro bisphenol A To Be Published 0 0 0 0 8PUO 38400529 Structural determinants of cold-activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas Ef 1 2023-07-17 2024-03-06 Gourlay, L.J.,Mangiagalli, M.,Moroni, E.,Lotti, M.,Nardini, M. Structural determinants of cold activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas sp. ef1. Febs J. 2024 0 0 0 8YOU The pmTcDH complex structure with an inhibitor SeCN 2024-03-13 2024-03-27 Varfolomeeva, L.A.,Polyakov, K.M.,Shipkov, N.S.,Dergousova, N.I.,Boyko, K.M.,Tikhonova, T.V.,Popov, V.O. The pmTcDH complex structure with an inhibitor SeCN To Be Published 0 0 0 0