PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 1BXE RIBOSOMAL PROTEIN L22 FROM THERMUS THERMOPHILUS 1998-10-02 1998-10-07 Unge, J.,berg, A.,Al-Kharadaghi, S.,Nikulin, A.,Nikonov, S.,Davydova, N.,Nevskaya, N.,Garber, M.,Liljas, A. The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. Structure 1998 6 1577 1586 1BXY 10531479 CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L30 FROM THERMUS THERMOPHILUS AT 1.9 A RESOLUTION: CONFORMATIONAL FLEXIBILITY OF THE MOLECULE. 1998-10-09 1998-10-14 Fedorov, R.,Nevskaya, N.,Khairullina, A.,Tishchenko, S.,Mikhailov, A.,Garber, M.,Nikonov, S. Structure of ribosomal protein L30 from Thermus thermophilus at 1.9 A resolution: conformational flexibility of the molecule. Acta Crystallogr.,Sect.D 1999 55 1827 1833 1FCP FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) FROM E.COLI IN COMPLEX WITH BOUND FERRICHROME-IRON 1998-10-14 1999-01-13 Ferguson, A.D.,Hofmann, E.,Coulton, J.W.,Diederichs, K.,Welte, W. Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide. Science 1998 282 2215 2220 2FCP FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) FROM E.COLI 1998-10-15 1999-01-13 Ferguson, A.D.,Hofmann, E.,Coulton, J.W.,Diederichs, K.,Welte, W. Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide. Science 1998 282 2215 2220 1B3N 10037680 BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN. 1998-12-14 1999-04-06 Moche, M.,Schneider, G.,Edwards, P.,Dehesh, K.,Lindqvist, Y. Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J.Biol.Chem. 1999 274 6031 6034 7MDH 10194350 STRUCTURAL BASIS FOR LIGHT ACITVATION OF A CHLOROPLAST ENZYME. THE STRUCTURE OF SORGHUM NADP-MALATE DEHYDROGENASE IN ITS OXIDIZED FORM 1999-02-16 1999-06-04 Johansson, K.,Ramaswamy, S.,Saarinen, M.,Lemaire-Chamley, M.,Issakidis-Bourguet, E.,Miginiac-Maslow, M.,Eklund, H. Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form. Biochemistry 1999 38 4319 4326 1RXG DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) AND 2-OXOGLUTARATE 1998-06-05 1999-06-08 Valegard, K.,van Scheltinga, A.C.,Lloyd, M.D.,Hara, T.,Ramaswamy, S.,Perrakis, A.,Thompson, A.,Lee, H.J.,Baldwin, J.E.,Schofield, C.J.,Hajdu, J.,Andersson, I. Structure of a cephalosporin synthase. Nature 1998 394 805 809 1RKA 10438599 THE APO FORM OF E. COLI RIBOKINASE 1999-03-22 1999-08-31 Sigrell, J.A.,Cameron, A.D.,Mowbray, S.L. Induced fit on sugar binding activates ribokinase. J.Mol.Biol. 1999 290 1009 1018 1B2L 10366509 ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE 1998-11-26 1999-11-26 Benach, J.,Atrian, S.,Gonzalez-Duarte, R.,Ladenstein, R. The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography. J.Mol.Biol. 1999 289 335 355 1DD5 10600747 CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME RECYCLING FACTOR, RRF 1999-11-08 1999-12-22 Selmer, M.,Al-Karadaghi, S.,Hirokawa, G.,Kaji, A.,Liljas, A. Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic. Science 1999 286 2349 2352 1DOZ 10704318 CRYSTAL STRUCTURE OF FERROCHELATASE 1999-12-22 2000-01-12 Lecerof, D.,Fodje, M.,Hansson, A.,Hansson, M.,Al-Karadaghi, S. Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol. 2000 297 221 232 7ATJ 10574977 RECOMBINANT HORSERADISH PEROXIDASE C1A COMPLEX WITH CYANIDE AND FERULIC ACID 1999-04-26 2000-01-14 Henriksen, A.,Smith, A.T.,Gajhede, M. The structures of the horseradish peroxidase C-ferulic acid complex and the ternary complex with cyanide suggest how peroxidases oxidize small phenolic substrates. J.Biol.Chem. 1999 274 35005 35011 1ECV 10702277 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 5-IODO-2-(OXALYL-AMINO)-BENZOIC ACID 2000-01-26 2000-03-15 Andersen, H.S.,Iversen, L.F.,Jeppesen, C.B.,Branner, S.,Norris, K.,Rasmussen, H.B.,Moller, K.B.,Moller, N.P. 2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases. J.Biol.Chem. 2000 275 7101 7108 1EIX 10757968 STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM E. COLI, CO-CRYSTALLISED WITH THE INHIBITOR BMP 2000-02-29 2000-03-15 Harris, P.,Poulsen, J.C.N.,Jensen, K.F.,Larsen, S. Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase. Biochemistry 2000 39 4217 4224 1C1H 10704318 CRYSTAL STRUCTURE OF BACILLUS SUBTILIS FERROCHELATASE IN COMPLEX WITH N-METHYL MESOPORPHYRIN 1999-07-22 2000-03-17 Lecerof, D.,Fodje, M.,Hansson, A.,Hansson, M.,Al-Karadaghi, S. Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol. 2000 297 221 232 1C9E 10704318 STRUCTURE OF FERROCHELATASE WITH COPPER(II) N-METHYLMESOPORPHYRIN COMPLEX BOUND AT THE ACTIVE SITE 1999-08-02 2000-03-22 Lecerof, D.,Fodje, M.,Hansson, A.,Hansson, M.,Al-Karadaghi, S. Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol. 2000 297 221 232 1ENF 10986116 CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 1.69 A RESOLUTION 2000-03-21 2000-04-19 Hakansson, M.,Petersson, K.,Nilsson, H.,Forsberg, G.,Bjork, P.,Antonsson, P.,Svensson, L.A. The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules. J.Mol.Biol. 2000 302 527 537 1C83 10702277 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 6-(OXALYL-AMINO)-1H-INDOLE-5-CARBOXYLIC ACID 2000-04-14 2000-05-03 Andersen, H.S.,Iversen, L.F.,Jeppesen, C.B.,Branner, S.,Norris, K.,Rasmussen, H.B.,Moller, K.B.,Moller, N.P. 2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases. J.Biol.Chem. 2000 275 7101 7108 1C84 10702277 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 3-(OXALYL-AMINO)-NAPHTHALENE-2-CARBOXLIC ACID 2000-04-14 2000-05-03 Andersen, H.S.,Iversen, L.F.,Jeppesen, C.B.,Branner, S.,Norris, K.,Rasmussen, H.B.,Moller, K.B.,Moller, N.P. 2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases. J.Biol.Chem. 2000 275 7101 7108 1C85 10702277 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO)-BENZOIC ACID 2000-04-16 2000-05-03 Andersen, H.S.,Iversen, L.F.,Jeppesen, C.B.,Branner, S.,Norris, K.,Rasmussen, H.B.,Moller, K.B.,Moller, N.P. 2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases. J.Biol.Chem. 2000 275 7101 7108 1C86 10744717 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B (R47V,D48N) COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID 2000-04-16 2000-05-03 Iversen, L.F.,Andersen, H.S.,Branner, S.,Mortensen, S.B.,Peters, G.H.,Norris, K.,Olsen, O.H.,Jeppesen, C.B.,Lundt, B.F.,Ripka, W.,Moller, K.B.,Moller, N.P. Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem. 2000 275 10300 10307 1C87 10744717 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID 2000-04-16 2000-05-03 Iversen, L.F.,Andersen, H.S.,Branner, S.,Mortensen, S.B.,Peters, G.H.,Norris, K.,Olsen, O.H.,Jeppesen, C.B.,Lundt, B.F.,Ripka, W.,Moller, K.B.,Moller, N.P. Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem. 2000 275 10300 10307 1C88 10744717 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID 2000-04-16 2000-05-03 Iversen, L.F.,Andersen, H.S.,Branner, S.,Mortensen, S.B.,Peters, G.H.,Norris, K.,Olsen, O.H.,Jeppesen, C.B.,Lundt, B.F.,Ripka, W.,Moller, K.B.,Moller, N.P. Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem. 2000 275 10300 10307 1CJS 10801481 CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L1 FROM METHANOCOCCUS JANNASCHII 1999-04-19 2000-05-31 Nevskaya, N.,Tischenko, S.,Fedorov, R.,Al-Karadaghi, S.,Liljas, A.,Kraft, A.,Piendl, W.,Garber, M.,Nikonov, S. Archaeal ribosomal protein L1: the structure provides new insights into RNA binding of the L1 protein family. Structure Fold.Des. 2000 8 363 371 1EWC 10986116 CRYSTAL STRUCTURE OF ZN2+ LOADED STAPHYLOCOCCAL ENTEROTOXIN H 2000-04-25 2000-05-31 Hakansson, M.,Petersson, K.,Nilsson, H.,Forsberg, G.,Bjork, P.,Antonsson, P.,Svensson, L.A. The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules. 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Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly. Proc. Natl. Acad. Sci. U.S.A. 2000 97 9907 9912 1GFY 10748206 RESIDUE 259 IS A KEY DETERMINANT OF SUBSTRATE SPECIFICITY OF PROTEIN-TYROSINE PHOSPHATASE 1B AND ALPHA 2000-06-26 2000-07-04 Peters, G.H.,Iversen, L.F.,Branner, S.,Andersen, H.S.,Mortensen, S.B.,Olsen, O.H.,Moller, K.B.,Moller, N.P. Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha. J.Biol.Chem. 2000 275 18201 18209 1F05 10869557 CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE 2000-05-14 2000-07-13 Thorell, S.,Gergely Jr., P.,Banki, K.,Perl, A.,Schneider, G. The three-dimensional structure of human transaldolase. FEBS Lett. 2000 475 205 208 1F77 10986116 STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 2.4 A RESOLUTION 2000-06-26 2000-07-19 Hakansson, M.,Petersson, K.,Nilsson, H.,Forsberg, G.,Bjork, P.,Antonsson, P.,Svensson, L.A. The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules. J.Mol.Biol. 2000 302 527 537 1QFG 10873859 E. COLI FERRIC HYDROXAMATE RECEPTOR (FHUA) 1999-04-10 2000-07-26 Ferguson, A.D.,Welte, W.,Hofmann, E.,Lindner, B.,Holst, O.,Coulton, J.W.,Diederichs, K. A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins. Structure Fold.Des. 2000 8 585 592 1C2Y 10595538 CRYSTAL STRUCTURES OF A PENTAMERIC FUNGAL AND AN ICOSAHEDRAL PLANT LUMAZINE SYNTHASE REVEALS THE STRUCTURAL BASIS FOR DIFFERENCES IN ASSEMBLY 1999-07-27 2000-07-30 Persson, K.,Schneider, G.,Jordan, D.B.,Viitanen, P.V.,Sandalova, T. Crystal structure analysis of a pentameric fungal and an icosahedral plant lumazine synthase reveals the structural basis for differences in assembly. 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Proc.Natl.Acad.Sci.USA 2000 97 9907 9912 1CV2 11087355 Hydrolytic haloalkane dehalogenase linb from sphingomonas paucimobilis UT26 AT 1.6 A resolution 1999-08-22 2000-09-11 Marek, J.,Vevodova, J.,Smatanova, I.K.,Nagata, Y.,Svensson, L.A.,Newman, J.,Takagi, M.,Damborsky, J. Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26. Biochemistry 2000 39 14082 14086 1D07 11087355 Hydrolytic haloalkane dehalogenase linb from sphingomonas paucimobilis UT26 with 1,3-propanediol, a product of debromidation of dibrompropane, at 2.0A resolution 1999-09-09 2000-09-11 Marek, J.,Vevodova, J.,Smatanova, I.K.,Nagata, Y.,Svensson, L.A.,Newman, J.,Takagi, M.,Damborsky, J. Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26. Biochemistry 2000 39 14082 14086 1E3E 10970744 Mouse class II alcohol dehydrogenase complex with NADH 2000-06-14 2000-09-12 Svensson, S.,Hoeoeg, J.O.,Schneider, G.,Sandalova, T. Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency J.Mol.Biol. 2000 302 441 0 1E3I 10970744 Mouse class II alcohol dehydrogenase complex with NADH and inhibitor 2000-06-16 2000-09-12 Svensson, S.,Hoeoeg, J.O.,Schneider, G.,Sandalova, T. Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency J.Mol.Biol. 2000 302 441 0 1E3L 10970744 P47H mutant of mouse class II alcohol dehydrogenase complex with NADH 2000-06-19 2000-09-12 Svensson, S.,Hoeoeg, J.O.,Schneider, G.,Sandalova, T. Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency J.Mol.Biol. 2000 302 441 0 1F41 10986125 CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN AT 1.5A RESOLUTION 2000-06-07 2000-09-20 Hornberg, A.,Eneqvist, T.,Olofsson, A.,Lundgren, E.,Sauer-Eriksson, A.E. 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J.Med.Chem. 2001 44 155 169 1IKV 11895437 K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz 2001-05-07 2001-06-06 Lindberg, J.,Sigurdsson, S.,Lowgren, S.,Andersson, H.O.,Sahlberg, C.,Noreen, R.,Fridborg, K.,Zhang, H.,Unge, T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Eur.J.Biochem. 2002 269 1670 1677 1IKW 11895437 Wild Type HIV-1 Reverse Transcriptase in Complex with Efavirenz 2001-05-07 2001-06-06 Lindberg, J.,Sigurdsson, S.,Lowgren, S.,Andersson, H.O.,Sahlberg, C.,Noreen, R.,Fridborg, K.,Zhang, H.,Unge, T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. 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J.Biol.Chem. 2003 278 25072 25080 1OQB 12704186 The Crystal Structure of the one-iron form of the di-iron center in Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean). 2003-03-07 2003-05-13 Moche, M.,Shanklin, J.,Ghoshal, A.,Lindqvist, Y. Azide and Acetate Complexes plus two iron-depleted Crystal Structures of the Di-iron Enzyme delta9 Stearoyl-ACP Desaturase-Implications for Oxygen Activation and Catalytic Intermediates J.Biol.Chem. 2003 278 25072 25080 1LD3 12761666 Crystal Structure of B. subilis ferrochelatase with Zn(2+) bound at the active site. 2002-04-08 2003-05-20 Lecerof, D.,Fodje, M.N.,Leon, R.A.,Olsson, U.,Hansson, A.,Sigfridsson, E.,Ryde, U.,Hansson, M.,Al-Karadaghi, S. Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem. 2003 8 452 458 1N0I 12761666 Crystal Structure of Ferrochelatase with Cadmium bound at active site 2002-10-14 2003-05-27 Lecerof, D.,Fodje, M.N.,Leon, R.A.,Olsson, U.,Hansson, A.,Sigfridsson, E.,Ryde, U.,Hansson, M.,Al-Karadaghi, S. Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem. 2003 8 452 458 1HJS 12761390 Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum. 2003-02-27 2003-06-02 Le Nours, J.,Ryttersgaard, C.,Lo Leggio, L.,Ostergaard, P.R.,Borchert, T.V.,Christensen, L.L.H.,Larsen, S. Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum Protein Sci. 2003 12 1195 0 1HJU 12761390 Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum. 2003-02-27 2003-06-02 Le Nours, J.,Ryttersgaard, C.,Lo Leggio, L.,Ostergaard, P.R.,Borchert, T.V.,Christensen, L.L.H.,Larsen, S. Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum Protein Sci. 2003 12 1195 0 1FOB 12484750 CRYSTAL STRUCTURE OF BETA-1,4-GALACTANASE FROM ASPERGILLUS ACULEATUS AT 100K 2000-08-27 2003-06-03 Ryttersgaard, C.,Leggio, L.L.,Coutinho, P.M.,Henrissat, B.,Larsen, S. Aspergillus aculeatus beta-1,4-Galactanase: Substrate Recognition and Relations to Other Glycoside Hydrolases in Clan GH-A Biochemistry 2002 41 15135 15143 1OGH 12756253 Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii 2003-05-02 2003-06-05 Johansson, E.,Bjornberg, O.,Nyman, P.O.,Larsen, S. Structure of the Bifunctional Dctp Deaminase-Dutpase from Methanocaldococcus Jannaschii and its Relation to Other Homotrimeric Dutpases J.Biol.Chem. 2003 278 27916 0 1NU3 12773375 Limonene-1,2-epoxide hydrolase in complex with valpromide 2003-01-30 2003-06-10 Arand, M.,Hallberg, B.M.,Zou, J.,Bergfors, T.,Oesch, F.,van der Werf, M.J.,de Bont, J.A.M.,Jones, T.A.,Mowbray, S.L. Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site EMBO J. 2003 22 2583 2592 1P5V 12787500 X-ray structure of the Caf1M:Caf1 chaperone:subunit preassembly complex 2003-04-28 2003-06-24 Zavialov, A.V.,Berglund, J.,Pudney, A.F.,Fooks, L.J.,Ibrahim, T.M.,MacIntyre, S.,Knight, S.D. Structure and Biogenesis of the Capsular F1 Antigen from Yersinia pestis. Preserved Folding Energy Drives Fiber Formation Cell(Cambridge,Mass.) 2003 113 587 596 1M61 12450381 Crystal structure of the apo SH2 domains of ZAP-70 2002-07-11 2003-07-15 Folmer, R.H.A.,Geschwindner, S.,Xue, Y. Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem Biochemistry 2002 41 14176 14184 1HJQ 12761390 Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum. 2003-02-27 2003-07-25 Le Nours, J.,Ryttersgaard, C.,Lo Leggio, L.,Ostergaard, P.R.,Borchert, T.V.,Christensen, L.L.H.,Larsen, S. Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum Protein Sci. 2003 12 1195 0 1K39 The structure of yeast delta3-delta2-enoyl-COA isomerase complexed with octanoyl-COA 2001-10-02 2003-08-05 0 0 0 0 1OVD 12732650 THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE 2003-03-26 2003-08-19 Norager, S.,Arent, S.,Bjornberg, O.,Ottesen, M.,Lo Leggio, L.,Jensen, K.F.,Larsen, S. Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J.Biol.Chem. 2003 278 28812 28822 1JAZ 25040257 Crystal Structure of Monoclinic Form of D90E Mutant of Escherichia coli Asparaginase II 2001-06-01 2003-09-09 Borek, D.,Kozak, M.,Pei, J.,Jaskolski, M. Crystal structure of active site mutant of antileukemic L-asparaginase reveals conserved zinc-binding site. Febs J. 2014 281 4097 4111 1JRB 12732650 The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A 2001-08-13 2003-09-09 Norager, S.,Arent, S.,Bjornberg, O.,Ottosen, M.,Lo Leggio, L.,Jensen, K.F.,Larsen, S. Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem. 2003 278 28812 28822 1OGO 12962629 Dex49A from Penicillium minioluteum complex with isomaltose 2003-05-08 2003-09-11 Larsson, A.M.,Andersson, R.,Stahlberg, J.,Kenne, L.,Jones, T.A. Dextranase from Penicillium Minioluteum. Reaction Course, Crystal Structure, and Product Complex Structure 2003 11 1111 0 1M6Z Crystal structure of reduced recombinant cytochrome c4 from Pseudomonas stutzeri 2002-07-18 2003-09-16 Noergaard, A.,Harris, P.,Larsen, S.,Christensen, H.E.M. Structural comparison of recombinant Pseudomonas stutzeri cytochrome c4 in two oxidation states To be Published 0 0 0 0 1M70 Crystal structure of oxidized recombinant cytochrome c4 from Pseudomonas stutzeri 2002-07-18 2003-09-16 Noergaard, A.,Harris, P.,Larsen, S.,Christensen, H.E.M. Structural comparison of recombinant Pseudomonas stutzeri cytochrome c4 in two oxidation states To be Published 0 0 0 0 1PUO 12851385 Crystal structure of Fel d 1- the major cat allergen 2003-06-25 2003-10-14 Kaiser, L.,Gronlund, H.,Sandalova, T.,Ljunggren, H.G.,van Hage-Hamsten, M.,Achour, A.,Schneider, G. The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J.Biol.Chem. 2003 278 37730 37735 1QZ1 14527396 Crystal Structure of the Ig 1-2-3 fragment of NCAM 2003-09-15 2003-11-04 Soroka, V.,Kolkova, K.,Kastrup, J.S.,Diederichs, K.,Breed, J.,Kiselyov, V.V.,Poulsen, F.M.,Larsen, I.K.,Welte, W.,Berezin, V.,Bock, E.,Kasper, C. Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion Structure 2003 11 1291 1301 1OLR 14627738 The Humicola grisea Cel12A Enzyme Structure at 1.2 A Resolution 2003-08-11 2003-11-25 Sandgren, M.,Gualfetti, P.J.,Paech, C.,Paech, S.,Shaw, A.,Gross, L.S.,Saldajeno, M.,Berglund, G.I.,Jones, T.A.,Mitchinson, C. The Humicola Grisea Cel12A Enzyme Structure at 1.2 A Resolution and the Impact of its Free Cysteine Residues on Thermal Stability Protein Sci. 2003 12 2782 0 1Q2B 14568538 CELLOBIOHYDROLASE CEL7A WITH DISULPHIDE BRIDGE ADDED ACROSS EXO-LOOP BY MUTATIONS D241C AND D249C 2003-07-24 2003-11-25 von Ossowski, I.,Stahlberg, J.,Koivula, A.,Piens, K.,Becker, D.,Boer, H.,Harle, R.,Harris, M.,Divne, C.,Mahdi, S.,Zhao, Y.,Driguez, H.,Claeyssens, M.,Sinnott, M.L.,Teeri, T.T. Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D. J.Mol.Biol. 2003 333 817 829 1R00 14607118 Crystal structure of aclacinomycin-10-hydroxylase (RdmB) in complex with S-adenosyl-L-homocysteine (SAH) 2003-09-19 2003-11-25 Jansson, A.,Niemi, J.,Lindqvist, Y.,Mantsala, P.,Schneider, G. Crystal Structure of Aclacinomycin-10-Hydroxylase, a S-Adenosyl-L-Methionine-dependent Methyltransferase Homolog Involved in Anthracycline Biosynthesis in Streptomyces purpurascens. J.Mol.Biol. 2003 334 269 280 1I2A CRYSTAL STRUCTURE OF L1 RIBOSOMAL PROTEIN FROM METHANOCOCCUS JANNASCHII WITH 1.85A RESOLUTION. 2001-02-07 2003-12-09 0 0 0 0 1N9G 12890667 Mitochondrial 2-enoyl thioester reductase Etr1p/Etr2p heterodimer from Candida tropicalis 2002-11-25 2003-12-09 Torkko, J.M.,Koivuranta, K.T.,Kastaniotis, A.J.,Airenne, T.T.,Glumoff, T.,Ilves, M.,Hartig, A.,Gurvitz, A.,Hiltunen, J.K. Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers. J.Biol.Chem. 2003 278 41213 41220 1P9Y 14656439 Ribosome binding of E. coli Trigger Factor mutant F44L. 2003-05-13 2003-12-16 Kristensen, O.,Gajhede, M. Chaperone binding at the ribosomal exit tunnel. Structure 2003 11 1547 1556 1USG 14672931 L-leucine-binding protein, apo form 2003-11-24 2003-12-18 Magnusson, U.,Salopek-Sondi, B.,Luck, L.A.,Mowbray, S.L. X-Ray Structures of the Leucine-Binding Protein Illustrate Conformational Changes and the Basis of Ligand Specificity J.Biol.Chem. 2004 279 8747 0 1USI 14672931 L-leucine-binding protein with phenylalanine bound 2003-11-24 2003-12-18 Magnusson, U.,Salopek-Sondi, B.,Luck, L.A.,Mowbray, S.L. X-Ray Structures of the Leucine-Binding Protein Illustrate Conformational Changes and the Basis of Ligand Specificity J.Biol.Chem. 2004 279 8747 0 1USK 14672931 L-leucine-binding protein with leucine bound 2003-11-25 2003-12-18 Magnusson, U.,Salopek-Sondi, B.,Luck, L.A.,Mowbray, S.L. X-Ray Structures of the Leucine-Binding Protein Illustrate Conformational Changes and the Basis of Ligand Specificity J.Biol.Chem. 2004 279 8747 0 1KTV Crystal Structure of Elongation Factor G Dimer Without Nucleotide 2002-01-17 2003-12-23 Laurberg, M.,Kristensen, O.,Su, X.D.,Liljas, A. A New Crystal Form of Thermus thermophilus Elongation Factor G Indicates Crystallographic Limitations Imposed on Molecular Flexibility To be Published 0 0 0 0 1NU5 12930985 Crystal structure of Pseudomonas sp. P51 Chloromuconate lactonizing enzyme 2003-01-31 2003-12-30 Kajander, T.,Lehtio, L.,Schlomann, M.,Goldman, A. The structure of Pseudomonas P51 Cl-muconate lactonizing enzyme: co-evolution of structure and dynamics with the dehalogenation function. Protein Sci. 2003 12 1855 1864 1UQ5 14686928 RICIN A-CHAIN (RECOMBINANT) N122A MUTANT 2003-10-15 2004-01-02 Marsden, C.J.,Fulop, V.,Day, P.,Lord, J.M. The Effect of Mutations Surrounding and within the Active Site on the Catalytic Activity of Ricin a Chain Eur.J.Biochem. 2004 271 153 0 1USL 14687575 Structure Of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, Complexed With Phosphate. 2003-11-25 2004-01-02 Roos, A.K.,Andersson, C.E.,Bergfors, T.,Jacobsson, M.,Karlen, A.,Unge, T.,Jones, T.A.,Mowbray, S.L. Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase Has a Known Fold, But a Novel Active Site J.Mol.Biol. 2004 335 799 0 1UNB 14718929 Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and ampicillin 2003-09-09 2004-01-09 Valegard, K.,Terwisscha van Scheltinga, A.C.,Dubus, A.,Ranghino, G.,Oster, L.M.,Hajdu, J.,Andersson, I. The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme Nat.Struct.Mol.Biol. 2004 11 95 101 1UOB 14718929 Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and penicillin G 2003-09-16 2004-01-09 Valegard, K.,Terwisscha van Scheltinga, A.C.,Dubus, A.,Ranghino, G.,Oster, L.M.,Hajdu, J.,Andersson, I. The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme Nat.Struct.Mol.Biol. 2004 11 95 101 1UOG 14718929 Deacetoxycephalosporin C synthase complexed with deacetoxycephalosporin C 2003-09-17 2004-01-09 Valegard, K.,Terwisscha van Scheltinga, A.C.,Dubus, A.,Ranghino, G.,Oster, L.M.,Hajdu, J.,Andersson, I. The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme Nat.Struct.Mol.Biol. 2004 11 95 101 1RIH 14627696 Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3 2003-11-17 2004-01-13 Krengel, U.,Olsson, L.-L.,Talavera, A.,Rojas, G.,Mier, E.,Moreno, E. Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3. J.Biol.Chem. 2004 279 5597 5603 1RIH 14627696 Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3 2003-11-17 2004-01-13 Krengel, U.,Olsson, L.-L.,Talavera, A.,Rojas, G.,Mier, E.,Moreno, E. Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3. J.Biol.Chem. 2004 279 5597 5603 1QV7 15023053 HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,3-DIFLUOROBENZYL ALCOHOL 2003-08-27 2004-01-20 LeBrun, L.A.,Park, D.-H.,Ramaswamy, S.,Plapp, B.V. Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase. Biochemistry 2004 43 3014 3026 1R7A 14756551 Sucrose Phosphorylase from Bifidobacterium adolescentis 2003-10-21 2004-02-10 Sprogoe, D.,van den Broek, L.A.,Mirza, O.,Kastrup, J.S.,Voragen, A.G.,Gajhede, M.,Skov, L.K. Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis. Biochemistry 2004 43 1156 1162 1OOW 14670610 The crystal structure of the spinach plastocyanin double mutant G8D/L12E gives insight into its low reactivity towards photosystem 1 and cytochrome f 2003-03-04 2004-02-17 Jansson, H.,Okvist, M.,Jacobson, F.,Ejdeback, M.,Hansson, O.,Sjolin, L. The crystal structure of the spinach plastocyanin double mutant G8D/L12E gives insight into its low reactivity towards photosystem 1 and cytochrome f. Biochim.Biophys.Acta 2003 1607 203 210 1UT4 15083810 Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors 2003-12-03 2004-03-19 Ernst, H.A.,Olsen, A.N.,Skriver, K.,Larsen, S.,Lo Leggio, L. Structure of the Conserved Domain of Anac, a Member of the Nac Family of Transcription Factors Embo Rep. 2004 5 297 0 1S06 14756557 Crystal Structure of the R253K Mutant of 7,8-Diaminopelargonic Acid Synthase 2003-12-30 2004-03-23 Sandmark, J.,Eliot, A.C.,Famm, K.,Schneider, G.,Kirsch, J.F. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry 2004 43 1213 1222 1S08 14756557 Crystal Structure of the D147N Mutant of 7,8-Diaminopelargonic Acid Synthase 2003-12-30 2004-03-23 Sandmark, J.,Eliot, A.C.,Famm, K.,Schneider, G.,Kirsch, J.F. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry 2004 43 1213 1222 1S09 14756557 Crystal Structure of the Y144F Mutant of 7,8-Diaminopelargonic Acid Synthase 2003-12-30 2004-03-23 Sandmark, J.,Eliot, A.C.,Famm, K.,Schneider, G.,Kirsch, J.F. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry 2004 43 1213 1222 1S0A 14756557 Crystal Structure of the Y17F Mutant of 7,8-Diaminopelargonic Acid Synthase 2003-12-30 2004-03-23 Sandmark, J.,Eliot, A.C.,Famm, K.,Schneider, G.,Kirsch, J.F. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry 2004 43 1213 1222 1S46 15023061 Covalent intermediate of the E328Q amylosucrase mutant 2004-01-15 2004-03-23 Jensen, M.H.,Mirza, O.,Albenne, C.,Remaud-Simeon, M.,Monsan, P.,Gajhede, M.,Skov, L.K. Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea. Biochemistry 2004 43 3104 3110 1H4F 16441657 E. COLI BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I K328R 2003-02-26 2004-03-29 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 1UUO 15044733 Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar 2004-01-08 2004-04-01 Hansen, M.,Le Nours, J.,Johansson, E.,Antal, T.,Ullrich, A.,Loffler, M.,Larsen, S. Inhibitor Binding in a Class 2 Dihydroorotate Dehydrogenase Causes Variations in the Membrane-Associated N-Terminal Domain Protein Sci. 2004 13 1031 0 1NL7 Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5 2003-01-06 2004-04-06 Kursula, P.,Wierenga, R.K. Crystal structures of Z. ramigera biosynthetic thiolase To be Published 0 0 0 0 1SJW 15071504 Structure of polyketide cyclase SnoaL 2004-03-04 2004-04-27 Sultana, A.,Kallio, P.,Jansson, A.,Wang, J.S.,Niemi, J.,Schneider, G. Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation. Embo J. 2004 23 1911 1921 1S7Q 15100292 Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants 2004-01-30 2004-05-04 Velloso, L.M.,Michaelsson, J.,Ljunggren, H.G.,Schneider, G.,Achour, A. Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol. 2004 172 5504 5511 1S7R 15100292 Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants 2004-01-30 2004-05-04 Velloso, L.M.,Michaelsson, J.,Ljunggren, H.G.,Schneider, G.,Achour, A. Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol. 2004 172 5504 5511 1S7T 15100292 Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants 2004-01-30 2004-05-04 Velloso, L.M.,Michaelsson, J.,Ljunggren, H.G.,Schneider, G.,Achour, A. Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol. 2004 172 5504 5511 1S7W 15100292 Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants 2004-01-30 2004-05-04 Velloso, L.M.,Michaelsson, J.,Ljunggren, H.G.,Schneider, G.,Achour, A. Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol. 2004 172 5504 5511 1S7X 15100292 Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants 2004-01-30 2004-05-04 Velloso, L.M.,Michaelsson, J.,Ljunggren, H.G.,Schneider, G.,Achour, A. Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol. 2004 172 5504 5511 1SI8 15272159 Crystal structure of E. faecalis catalase 2004-02-28 2004-05-04 Hakansson, K.O.,Brugna, M.,Tasse, L. The three-dimensional structure of catalase from Enterococcus faecalis. Acta Crystallogr.,Sect.D 2004 60 1374 1380 1ROA 15728581 Structure of human cystatin D 2003-12-01 2004-05-18 Alvarez-Fernandez, M.,Liang, Y.H.,Abrahamson, M.,Su, X.D. Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile. J.Biol.Chem. 2005 280 18221 18228 1UWZ 15147186 Bacillus subtilis cytidine deaminase with an Arg56 - Ala substitution 2004-02-18 2004-05-20 Johansson, E.,Neuhard, J.,Willemoes, M.,Larsen, S. Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase Biochemistry 2004 43 6020 0 1UX0 15147186 Bacillus subtilis cytidine deaminase with an Arg56 - Gln substitution 2004-02-18 2004-05-20 Johansson, E.,Neuhard, J.,Willemoes, M.,Larsen, S. Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase Biochemistry 2004 43 6020 0 1UHL 12970175 Crystal structure of the LXRalfa-RXRbeta LBD heterodimer 2003-07-03 2004-06-01 Svensson, S.,Ostberg, T.,Jacobsson, M.,Norstrom, C.,Stefansson, K.,Hallen, D.,Johansson, I.C.,Zachrisson, K.,Ogg, D.,Jendeberg, L. Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation Embo J. 2003 22 4625 4633 1PKW 16421451 Crystal structure of human glutathione transferase (GST) A1-1 in complex with glutathione 2003-06-06 2004-06-22 Grahn, E.,Novotny, M.,Jakobsson, E.,Gustafsson, A.,Grehn, L.,Olin, B.,Madsen, D.,Wahlberg, M.,Mannervik, B.,Kleywegt, G.J. New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix. 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Biochim.Biophys.Acta 2004 1698 37 44 1SYY 15247479 Crystal structure of the R2 subunit of ribonucleotide reductase from Chlamydia trachomatis 2004-04-02 2004-07-13 Hogbom, M.,Stenmark, P.,Voevodskaya, N.,McClarty, G.,Graslund, A.,Nordlund, P. The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass. Science 2004 305 245 248 1Q3I 14499619 Crystal Structure of Na,K-ATPase N-domain 2003-07-30 2004-08-03 Hakansson, K.O. The Crystallographic Structure of Na,K-ATPase N-domain at 2.6 A Resolution J.Mol.Biol. 2003 332 1175 1182 1SQM 15078870 STRUCTURE OF [R563A] LEUKOTRIENE A4 HYDROLASE 2004-03-19 2004-08-03 Rudberg, P.C.,Tholander, F.O.T.,Andberg, M.,Thunnissen, M.M.G.M. 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Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family Biochemistry 2004 43 8894 8900 1U8E 15175333 HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 MUTANT Y547F 2004-08-05 2004-08-17 BJELKE, J.R.,CHRISTENSEN, J.,BRANNER, S.,WAGTMANN, N.,OLSEN, C.,KANSTRUP, A.B.,RASMUSSEN, H.B. Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV J.Biol.Chem. 2004 279 34691 34697 1W69 15322079 Crystal Structure of Mouse Ribonucleotide Reductase Subunit R2 under Reducing Conditions. A Fully Occupied Dinuclear Iron Cluster and Bound Acetate. 2004-08-16 2004-08-26 Strand, K.R.,Karlsen, S.,Kolberg, M.,Rohr, A.K.,Gorbitz, C.H.,Andersson, K.K. Crystal Structural Studies of Changes in the Native Dinuclear Iron Center of Ribonucleotide Reductase Protein R2 from Mouse J.Biol.Chem. 2004 279 46794 0 1TDQ 15296743 Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins 2004-05-24 2004-08-31 Lundell, A.,Olin, A.I.,Moergelin, M.,al-Karadaghi, S.,Aspberg, A.,Logan, D.T. Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins Structure 2004 12 1495 1506 1USB 15333749 Rational design of a novel enzyme - efficient thioester hydrolysis enabled by the incorporation of a single His residue into human glutathione transferase A1-1 2003-11-20 2004-09-01 Hederos, S.,Broo, K.S.,Jakobsson, E.,Kleywegt, G.J.,Mannervik, B.,Baltzer, L. Incorporation of a Single His Residue by Rational Design Enables Thiol-Ester Hydrolysis by Human Glutathione Transferase A1-1 Proc.Natl.Acad.Sci.USA 2004 101 13163 0 1TW3 15273252 Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET) 2004-06-30 2004-09-14 Jansson, A.,Koskiniemi, H.,Mantsala, P.,Niemi, J.,Schneider, G. Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products J.Biol.Chem. 2004 279 41149 41156 1U2R 15316019 Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae 2004-07-20 2004-09-14 Jorgensen, R.,Yates, S.P.,Teal, D.J.,Nilsson, J.,Prentice, G.A.,Merrill, A.R.,Andersen, G.R. Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae J.Biol.Chem. 2004 279 45919 45925 1R4C 15312769 N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping 2003-10-06 2004-09-21 Janowski, R.,Abrahamson, M.,Grubb, A.,Jaskolski, M. Domain swapping in N-truncated human cystatin C. J.Mol.Biol. 2004 341 151 160 1MZY Crystal Structure of Nitrite Reductase 2002-10-10 2004-09-28 Guo, H.,Olesen, K.,Xue, Y.,Shapliegh, J.,Sjolin, L. The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center To be Published 0 0 0 0 1N70 The Crystal Structure of Nitrite Reductase Mutant His287Ala from Rhodobacter Sphaeroides 2002-11-12 2004-09-28 Guo, H.,Olesen, K.,Shapliegh, J.,Sjolin, L. The Crystal Structure of Nitrite Reductase Mutant His287Ala from Rhodobacter Sphaeroides to 1.6 Resolution To be Published 0 0 0 0 1W5Y 15560801 HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor 2004-08-10 2004-10-07 Lindberg, J.,Pyring, D.,Loewgren, S.,Rosenquist, A.,Zuccarello, G.,Kvarnstroem, I.,Zhang, H.,Vrang, L.,Claesson, B.,Hallberg, A.,Samuelsson, B.,Unge, T. Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem. 2004 271 4594 0 1TJC 15456751 Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase 2004-06-04 2004-10-12 Pekkala, M.,Hieta, R.,Bergmann, U.,Kivirikko, K.I.,Wierenga, R.K.,Myllyharju, J. 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Effects of a novel disulfide bond and engineered electrostatic interactions on the thermostability of azurin Biochemistry 2004 43 12563 12574 1URL 15488769 N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE) IN COMPLEX WITH GLYCOPEPTIDE 2003-10-31 2004-10-20 Bukrinsky, J.T.,Hilaire, P.M.S.,Meldal, M.,Crocker, P.R.,Henriksen, A. Complex of Sialoadhesin with a Glycopeptide Ligand Biochim.Biophys.Acta 2004 1702 173 0 1TJ7 15502303 Structure determination and refinement at 2.44 A resolution of Argininosuccinate lyase from E. coli 2004-06-03 2004-10-26 Bhaumik, P.,Koski, M.K.,Bergmann, U.,Wierenga, R.K. Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli. Acta Crystallogr.,Sect.D 2004 60 1964 1970 1WBK HIV-1 protease in complex with asymmetric inhibitor, BEA568 2004-11-02 2004-11-04 Lindberg, J.,Unge, T. 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Crystal Structure of CaiB, a Type-III CoA Transferase in Carnitine Metabolism Biochemistry 2004 43 13996 14003 1XSE 15542590 Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1 2004-10-19 2004-11-16 Ogg, D.,Elleby, B.,Norstrom, C.,Stefansson, K.,Abrahmsen, L.,Oppermann, U.,Svensson, S. The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions J.Biol.Chem. 2005 280 3789 3794 1W5V 15560801 HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor 2004-08-10 2004-12-01 Lindberg, J.,Pyring, D.,Loewgren, S.,Rosenquist, A.,Zuccarello, G.,Kvarnstroem, I.,Zhang, H.,Vrang, L.,Claesson, B.,Hallberg, A.,Samuelsson, B.,Unge, T. Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy Eur.J.Biochem. 2004 271 4594 0 1W07 15581893 Arabidopsis thaliana acyl-CoA oxidase 1 2004-06-01 2004-12-15 Pedersen, L.,Henriksen, A. Acyl-Coa Oxidase 1 from Arabidopsis Thaliana. Structure of a Key Enzyme in Plant Lipid Metabolism J.Mol.Biol. 2005 345 487 0 1XS1 15539408 dCTP deaminase from Escherichia coli in complex with dUTP 2004-10-18 2004-12-21 Johansson, E.,Fano, M.,Bynck, J.H.,Neuhard, J.,Larsen, S.,Sigurskjold, B.W.,Christensen, U.,Willemoes, M. 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Altered Intersubunit Interactions in Crystal Structures of Catalytically Compromised Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase Biochemistry 2005 44 113 0 1W4W 15641789 Ferric horseradish peroxidase C1A in complex with formate 2004-08-03 2005-01-19 Carlsson, G.H.,Nicholls, P.,Svistunenko, D.,Berglund, G.I.,Hajdu, J. Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry 2005 44 635 0 1W4Y 15641789 Ferrous horseradish peroxidase C1A in complex with carbon monoxide 2004-08-03 2005-01-19 Carlsson, G.H.,Nicholls, P.,Svistunenko, D.,Berglund, G.I.,Hajdu, J. Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry 2005 44 635 0 1XTT 15654744 Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) 2004-10-24 2005-02-08 Arent, S.,Harris, P.,Jensen, K.F.,Larsen, S. Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry 2005 44 883 892 1XTU 15654744 Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) and cytidine 5'-triphosphate (CTP) 2004-10-24 2005-02-08 Arent, S.,Harris, P.,Jensen, K.F.,Larsen, S. Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry 2005 44 883 892 1XTV 15654744 Sulfolobus solfataricus uracil phosphoribosyltransferase with uridine 5'-monophosphate (UMP) bound to half of the subunits 2004-10-24 2005-02-08 Arent, S.,Harris, P.,Jensen, K.F.,Larsen, S. 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Acta Crystallogr.,Sect.D 2005 61 1190 1198 1TYO 15581899 Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix in complex with etheno-NADP 2004-07-08 2005-07-08 Karlstrom, M.,Stokke, R.,Steen, I.H.,Birkeland, N.K.,Ladenstein, R. Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol. 2005 345 559 577 2A3T 16131751 Cu-containing nitrite reductase 2005-06-27 2005-08-02 Jacobson, F.,Guo, H.,Olesen, K.,Okvist, M.,Neutze, R.,Sjolin, L. Structures of the oxidized and reduced forms of nitrite reductase from Rhodobacter sphaeroides 2.4.3 at high pH: changes in the interactions of the type 2 copper. Acta Crystallogr.,Sect.D 2005 61 1190 1198 2AIX X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution. 2005-08-01 2005-08-09 Holm, M.M.,Lunn, M.L.,Traynelis, S.F.,Kastrup, J.S.,Egebjerg, J. Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex. To be Published 0 0 0 0 2BV3 16083884 Crystal structure of a mutant elongation factor G trapped with a GTP analogue 2005-06-22 2005-08-10 Hansson, S.,Singh, R.,Gudkov, A.T.,Liljas, A.,Logan, D.T. Crystal Structure of a Mutant Elongation Factor G Trapped with a GTP Analogue. FEBS Lett. 2005 579 4492 0 1U9Z 16288921 Crystal Structure of Phosphoribosyl Diphosphate Synthase Complexed with AMP and Ribose 5-Phosphate 2004-08-11 2005-08-23 Kadziola, A.,Jepsen, C.H.,Johansson, E.,McGuire, J.,Larsen, S.,Hove-Jensen, B. 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The Structure and Characterization of a Modular Endo-Beta-1,4-Mannanase from Cellulomonas Fimi Biochemistry 2005 44 12700 0 1XKD 15581899 Ternary complex of Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix 2004-09-28 2005-10-04 Karlstrom, M.,Stokke, R.,Steen, I.H.,Birkeland, N.-K.,Ladenstein, R. Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. J.Mol.Biol. 2005 345 559 577 2BOD 16185060 Catalytic domain of endo-1,4-glucanase Cel6A from Thermobifida fusca in complex with methyl cellobiosyl-4-thio-beta-cellobioside 2005-04-10 2005-10-05 Larsson, A.M.,Bergfors, T.,Dultz, E.,Irwin, D.C.,Roos, A.,Driguez, H.,Wilson, D.B.,Jones, T.A. Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry 2005 44 12915 0 2BOF 16185060 Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca in complex with cellotetrose 2005-04-10 2005-10-05 Larsson, A.M.,Bergfors, T.,Dultz, E.,Irwin, D.C.,Roos, A.,Driguez, H.,Wilson, D.B.,Jones, T.A. Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry 2005 44 12915 0 2C4K Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39) 2005-10-20 2005-10-24 Kursula, P.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Flodin, S.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Kotenyova, T.,Nilsson-Ehle, P.,Ogg, D.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Nordlund, P. Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39) To be Published 0 0 0 0 1TEF Crystal structure of the spinach plastocyanin mutants G8D/K30C/T69C and K30C/T69C- a study of the effect on crystal packing and thermostability from the introduction of a novel disulfide bond 2004-05-25 2005-11-01 Okvist, M.,Jacobson, F.,Jansson, H.,Hansson, O.,Sjolin, L. Novel Disulfide Bonds Effect the Thermostability of Plastocyanin. Crystal structures of the triple plastocyanin mutant G8D/K30C/T69C and the double plastocyanin mutant K30C/T69C from spinach at 1.90 and 1.96 resolution, respectively. To be Published 0 0 0 0 1TEG Crystal structure of the spinach plastocyanin mutants G8D/K30C/T69C and K30C/T69C- a study of the effect on crystal packing and thermostability from the introduction of a novel disulfide bond 2004-05-25 2005-11-01 Okvist, M.,Jacobson, F.,Jansson, H.,Hansson, O.,Sjolin, L. Novel Disulfide Bonds Effect the Thermostability of Plastocyanin. Crystal structures of the triple plastocyanin mutant G8D/K30C/T69C and the double plastocyanin mutant K30C/T69C from spinach at 1.90 A and 1.96 A resolution, respectively. To be Published 0 0 0 0 1XWG 16421451 Human GST A1-1 T68E mutant 2004-11-01 2005-11-01 Grahn, E.,Novotny, M.,Jakobsson, E.,Gustafsson, A.,Grehn, L.,Olin, B.,Madsen, D.,Wahlberg, M.,Mannervik, B.,Kleywegt, G.J. New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix. Acta Crystallogr.,Sect.D 2006 62 197 207 1XJK 15475969 Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex 2004-09-23 2005-11-22 Larsson, K.-M.,Jordan, A.,Eliasson, R.,Reichard, P.,Logan, D.T.,Nordlund, P. Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol. 2004 11 1142 1149 2BQV 16335934 HIV-1 protease in complex with inhibitor AHA455 2005-04-28 2005-12-14 Ekegren, J.K.,Unge, T.,Safa, M.Z.,Wallberg, H.,Samuelsson, B.,Hallberg, A. A New Class of HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold. J.Med.Chem. 2005 48 8098 0 1XJF 15475969 Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex 2004-09-23 2005-12-20 Larsson, K.-M.,Jordan, A.,Eliasson, R.,Reichard, P.,Logan, D.T.,Nordlund, P. Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol. 2004 11 1142 1149 1XJJ 15475969 Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP complex 2004-09-23 2005-12-20 Larsson, K.-M.,Jordan, A.,Eliasson, R.,Reichard, P.,Logan, D.T.,Nordlund, P. Structural Mechanism of Allosteric Substrate Specificity Regulation in a Ribonucleotide Reductase Nat.Struct.Mol.Biol. 2005 11 1142 1149 2C50 11720290 MS2-RNA HAIRPIN (A -5) COMPLEX 2005-10-25 2006-01-05 Grahn, E.,Moss, T.,Helgstrand, C.,Fridborg, K.,Sundaram, M.,Tars, K.,Lago, H.,Stonehouse, N.J.,Davis, D.R.,Stockley, P.G.,Liljas, L. Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna 2001 7 1616 1627 2C0P 16388582 Aged form of mouse acetylcholinesterase inhibited by tabun 2005-09-07 2006-01-09 Ekstrom, F.,Akfur, C.,Tunemalm, A.-K.,Lundberg, S. Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry 2006 45 74 0 2C0Q 16388582 non-aged form of mouse acetylcholinesterase inhibited by tabun 2005-09-07 2006-01-09 Ekstrom, F.,Akfur, C.,Tunemalm, A.-K.,Lundberg, S. Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry 2006 45 74 0 1ZCJ 16330050 Crystal structure of 3-hydroxyacyl-CoA dehydrogenase 2005-04-12 2006-01-10 Taskinen, J.P.,Kiema, T.R.,Hiltunen, J.K.,Wierenga, R.K. Structural Studies of MFE-1: the 1.9A Crystal Structure of the Dehydrogenase Part of Rat Peroxisomal MFE-1 J.Mol.Biol. 2006 355 734 746 2BYX 16441657 KAS I LYS328ALA Mutant in complex with fatty acid 2005-08-09 2006-02-01 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 2BYY 16441657 E.coli KAS I H298E Mutation 2005-08-09 2006-02-01 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 2BYZ 16441657 Structure of E.coli KAS I H298Q mutant in complex with C12 fatty acid 2005-08-09 2006-02-01 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 2BZ3 16441657 Structure of E.coli KAS I H298E mutant in complex with C12 fatty acid 2005-08-10 2006-02-01 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 2BZ4 16441657 structure of E.coli KAS I H298Q mutant 2005-08-10 2006-02-01 von Wettstein-Knowles, P.,Olsen, J.G.,McGuire, K.A.,Henriksen, A. Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J. 2006 273 695 710 2F74 16375919 Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33 2005-11-30 2006-02-14 Achour, A.,Harris, R.A.,Ljunggren, H.G.,Schneider, G.,Sandalova, T. Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin. J.Mol.Biol. 2006 356 382 396 2FPD 16456539 Sad structure determination: crystal structure of the intrinsic dimerization sh3 domain of the ib1 scaffold protein 2006-01-16 2006-02-28 Kristensen, O.,Guenat, S.,Dar, I.,Allaman-Pillet, N.,Abderrahmani, A.,Ferdaoussi, M.,Roduit, R.,Maurer, F.,Beckmann, J.S.,Kastrup, J.S.,Gajhede, M.,Bonny, C. A unique set of SH3-SH3 interactions controls IB1 homodimerization Embo J. 2006 25 785 797 2CCR 19089956 Structure of Beta-1,4-Galactanase 2006-01-18 2006-03-21 Le Nours, J.,De Maria, L.,Welner, D.,Jorgensen, C.T.,Christensen, L.L.H.,Borchert, T.V.,Larsen, S.,Lo Leggio, L. Investigating the Binding of Beta-1,4-Galactan to Bacillus Licheniformis Beta-1,4-Galactanase by Crystallography and Computational Modeling. Proteins 2009 75 977 0 2FF6 16531231 Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin 2005-12-19 2006-03-21 Aguda, A.H.,Xue, B.,Irobi, E.,Preat, T.,Robinson, R.C. The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins Structure 2006 14 469 476 2BNY 16531233 MS2 (N87A mutant) - RNA hairpin complex 2005-04-06 2006-03-22 Horn, W.T.,Tars, K.,Grahn, E.,Helgstrand, C.,Baron, A.J.,Lago, H.,Adams, C.J.,Peabody, D.S.,Phillips, S.E.V.,Stonehouse, N.J.,Liljas, L.,Stockley, P.G. Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2. Structure 2006 14 487 0 2BQ5 16531233 MS2 (N87AE89K mutant) - RNA hairpin complex 2005-04-27 2006-03-22 Horn, W.T.,Tars, K.,Grahn, E.,Helgstrand, C.,Baron, A.J.,Lago, H.,Adams, C.J.,Peabody, D.S.,Phillips, S.E.V.,Stonehouse, N.J.,Liljas, L.,Stockley, P.G. Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2. Structure 2006 14 487 0 2FP2 16499927 Secreted Chorismate Mutase from Mycobacterium tuberculosis 2006-01-15 2006-03-28 Okvist, M.,Dey, R.,Sasso, S.,Grahn, E.,Kast, P.,Krengel, U. 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed J.Mol.Biol. 2006 357 1483 1499 2GIM 16929103 1.6 Angstrom structure of plastocyanin from Anabaena variabilis 2006-03-29 2006-04-11 Schmidt, L.,Christensen, H.E.,Harris, P. Structure of plastocyanin from the cyanobacterium Anabaena variabilis. ACTA CRYSTALLOGR.,SECT.D 2006 62 1022 1029 2FGH 16469333 ATP bound gelsolin 2005-12-22 2006-04-18 Urosev, D.,Ma, Q.,Tan, A.L.C.,Robinson, R.C.,Burtnick, L.D. The structure of gelsolin bound to ATP J.Mol.Biol. 2006 357 765 772 1ZS2 Amylosucrase Mutant E328Q in a ternary complex with sucrose and maltoheptaose 2005-05-23 2006-05-02 Skov, L.K.,Mirza, O.,Sprogoe, D.,van der Veen, B.A.,Remaud-Simeon, M.,Albenne, C.,Monsan, P.,Gajhede, M. Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose BIOCATAL.BIOTRANSFOR. 2006 24 99 105 1ZKR Crystal structure of the major cat allergen Fel d 1 (1+2) 2005-05-04 2006-05-16 Kaiser, L.,Cirkovic Velickovic, T.,Adedoyin, J.,Thunberg, S.,Gronlund, H.,Gafvelin, G.,van Hage, M.,Achour, A. Crystal structure of the major cat allergen Fel d 1 (1+2) To be Published 0 0 0 0 1ZOR 16759231 Isocitrate dehydrogenase from the hyperthermophile Thermotoga maritima 2005-05-13 2006-05-16 Karlstrom, M.,Steen, I.H.,Madern, D.,Fedoy, A.E.,Birkeland, N.K.,Ladenstein, R. The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima. Febs J. 2006 273 2851 2868 2ATM 16699186 Crystal structure of the recombinant allergen Ves v 2 2005-08-25 2006-05-23 Skov, L.K.,Seppala, U.,Coen, J.J.,Crickmore, N.,King, T.P.,Monsalve, R.,Kastrup, J.S.,Spangfort, M.D.,Gajhede, M. Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom. Acta Crystallogr.,Sect.D 2006 62 595 604 2FH1 16466744 C-terminal half of gelsolin soaked in low calcium at pH 4.5 2005-12-23 2006-06-13 Chumnarnsilpa, S.,Loonchanta, A.,Xue, B.,Choe, H.,Urosev, D.,Wang, H.,Lindberg, U.,Burtnick, L.D.,Robinson, R.C. Calcium ion exchange in crystalline gelsolin J.Mol.Biol. 2006 357 773 782 2FH2 16466744 C-terminal half of gelsolin soaked in EGTA at pH 4.5 2005-12-23 2006-06-13 Chumnarnsilpa, S.,Loonchanta, A.,Xue, B.,Choe, H.,Urosev, D.,Wang, H.,Lindberg, U.,Burtnick, L.D.,Robinson, R.C. Calcium ion exchange in crystalline gelsolin J.Mol.Biol. 2006 357 773 782 2FH3 16466744 C-terminal half of gelsolin soaked in low calcium at pH 8 2005-12-23 2006-06-13 Chumnarnsilpa, S.,Loonchanta, A.,Xue, B.,Choe, H.,Urosev, D.,Wang, H.,Lindberg, U.,Burtnick, L.D.,Robinson, R.C. Calcium ion exchange in crystalline gelsolin J.Mol.Biol. 2006 357 773 782 2FH4 16466744 C-terminal half of gelsolin soaked in EGTA at pH 8 2005-12-23 2006-06-13 Chumnarnsilpa, S.,Loonchanta, A.,Xue, B.,Choe, H.,Urosev, D.,Wang, H.,Lindberg, U.,Burtnick, L.D.,Robinson, R.C. Calcium ion exchange in crystalline gelsolin J.Mol.Biol. 2006 357 773 782 2GFT Crystal structure of the E263A nucleophile mutant of Bacillus licheniformis endo-beta-1,4-galactanase in complex with galactotriose 2006-03-23 2006-06-13 Le Nours, J.,De Maria, L.,Welner, D.,Jorgensen, C.T.,Christensen, L.L.H.,Larsen, S.,Lo Leggio, L. Oligosaccharide binding of Bacillus licheniformis endo-beta-1,4-galactanase To be Published 0 0 0 0 2BGS 18300247 HOLO ALDOSE REDUCTASE FROM BARLEY 2005-01-05 2006-06-22 Olsen, J.G.,Pedersen, L.,Christensen, C.L.,Olsen, O.,Henriksen, A. Barley Aldose Reductase: Structure, Cofactor Binding, and Substrate Recognition in the Aldo/Keto Reductase 4C Family. Proteins: Struct., Funct., Bio 2008 71 1572 0 1W6H Novel plasmepsin II-inhibitor complex 2004-08-18 2006-07-05 Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T. Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published 0 0 0 0 1W6I plasmepsin II-pepstatin A complex 2004-08-18 2006-07-05 Lindberg, J.,Johansson, P.-O.,Rosenquist, A.,Kvarnstroem, I.,Vrang, L.,Samuelsson, B.,Unge, T. Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design To be Published 0 0 0 0 2C4I 16787776 Crystal structure of engineered avidin 2005-10-19 2006-07-05 Hytonen, V.P.,Horha, J.,Airenne, T.T.,Niskanen, E.A.,Helttunen, K.,Johnson, M.S.,Salminen, T.A.,Kulomaa, M.S.,Nordlund, H.R. Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin. J.Mol.Biol. 2006 359 1352 0 2ANI 17827077 Crystal structure of the F127Y mutant of Ribonucleotide Reductase R2 from Chlamydia trachomatis 2005-08-11 2006-07-25 Voevodskaya, N.,Galander, M.,Hogbom, M.,Stenmark, P.,McClarty, G.,Graslund, A.,Lendzian, F. Structure of the high-valent FeIIIFeIV state in ribonucleotide reductase (RNR) of Chlamydia trachomatis--combined EPR, 57Fe-, 1H-ENDOR and X-ray studies. Biochim.Biophys.Acta 2007 1774 1254 1263 2IZ9 11095669 MS2-RNA HAIRPIN (4ONE -5) COMPLEX 2006-07-25 2006-07-27 Grahn, E.,Stonehouse, N.J.,Adams, C.J.,Fridborg, K.,Beigelman, L.,Matulic-Adamic, J.,Warriner, S.L.,Stockley, P.G.,Liljas, L. Deletion of a Single Hydrogen Bonding Atom from the MS2 RNA Operator Leads to Dramatic Rearrangements at the RNA-Coat Protein Interface Nucleic Acids Res. 2000 28 4611 0 2IX5 16887802 Short chain specific acyl-CoA oxidase from Arabidopsis thaliana, ACX4 in complex with acetoacetyl-CoA 2006-07-07 2006-08-08 Mackenzie, J.,Pedersen, L.,Arent, S.,Henriksen, A. Controlling Electron Transfer in Acyl-Coa Oxidases and Dehydrogenases: A Structural View. J.Biol.Chem. 2006 281 31012 0 2IX6 16887802 SHORT CHAIN SPECIFIC ACYL-COA OXIDASE FROM ARABIDOPSIS THALIANA, ACX4 2006-07-07 2006-08-08 Mackenzie, J.,Pedersen, L.,Arent, S.,Henriksen, A. Controlling Electron Transfer in Acyl-Coa Oxidases and Dehydrogenases: A Structural View. J.Biol.Chem. 2006 281 31012 0 2GYU 16876764 Crystal structure of Mus musculus Acetylcholinesterase in complex with HI-6 2006-05-10 2006-08-15 Ekstrom, F.,Pang, Y.P.,Boman, M.,Artursson, E.,Akfur, C.,Borjegren, S. Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates. Biochem.Pharm. 2006 72 597 607 2GYV 16876764 Crystal structure of Mus musculus Acetylcholinesterase in complex with Ortho-7 2006-05-10 2006-08-15 Ekstrom, F.,Pang, Y.P.,Boman, M.,Artursson, E.,Akfur, C.,Borjegren, S. Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates. Biochem.Pharm. 2006 72 597 607 2FRX 16793063 Crystal structure of YebU, a m5C RNA methyltransferase from E.coli 2006-01-20 2006-08-29 Hallberg, B.M.,Ericsson, U.B.,Johnson, K.A.,Andersen, N.M.,Douthwaite, S.,Nordlund, P.,Beuscher IV, A.E.,Erlandsen, H. The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain J.Mol.Biol. 2006 360 774 787 2C4E 16929110 Crystal Structure of Methanocaldococcus jannaschii Nucleoside Kinase - An Archaeal Member of the Ribokinase Family 2005-10-18 2006-08-30 Arnfors, L.,Hansen, T.,Schoenheit, P.,Ladenstein, R.,Meining, W. Structure of Methanocaldococcus Jannaschii Nucleoside Kinase: An Archaeal Member of the Ribokinase Family. Acta Crystallogr.,Sect.D 2006 62 1085 0 2HP3 16934291 Crystal structure of iminodisuccinate epimerase 2006-07-17 2006-09-12 Lohkamp, B.,Bauerle, B.,Rieger, P.G.,Schneider, G. Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family. J.Mol.Biol. 2006 362 555 566 2HP3 16934291 Crystal structure of iminodisuccinate epimerase 2006-07-17 2006-09-12 Lohkamp, B.,Bauerle, B.,Rieger, P.G.,Schneider, G. Three-dimensional Structure of Iminodisuccinate Epimerase Defines the Fold of the MmgE/PrpD Protein Family. J.Mol.Biol. 2006 362 555 566 2IGK 16984920 Crystal structure of recombinant pyranose 2-oxidase 2006-09-22 2006-10-10 Kujawa, M.,Ebner, H.,Leitner, C.,Hallberg, B.M.,Prongjit, M.,Sucharitakul, J.,Ludwig, R.,Rudsander, U.,Peterbauer, C.,Chaiyen, P.,Haltrich, D.,Divne, C. Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase. J.Biol.Chem. 2006 281 35104 35115 2IGO 16984920 Crystal structure of pyranose 2-oxidase H167A mutant with 2-fluoro-2-deoxy-D-glucose 2006-09-22 2006-10-10 Kujawa, M.,Ebner, H.,Leitner, C.,Hallberg, B.M.,Prongjit, M.,Sucharitakul, J.,Ludwig, R.,Rudsander, U.,Peterbauer, C.,Chaiyen, P.,Haltrich, D.,Divne, C. Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase. J.Biol.Chem. 2006 281 35104 35115 1ZWS Crystal structure of the catalytic domain of human DRP-1 kinase 2005-06-06 2006-10-24 Kursula, P.,Schunck, H.,Wilmanns, M. Crystal structure of the catalytic domain of human DRP-1 kinase To be Published 0 0 0 0 2DJF 17020538 Crystal Structure of human dipeptidyl peptidase I (Cathepsin C) in complex with the inhibitor Gly-Phe-CHN2 2006-04-02 2006-11-14 Molgaard, A.,Arnau, J.,Lauritzen, C.,Larsen, S.,Petersen, G.,Pedersen, J. The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2 Biochem.J. 2007 401 645 650 2NPF 17082187 Structure of eEF2 in complex with moriniafungin 2006-10-27 2006-11-14 Soe, R.,Mosley, R.T.,Justice, M.,Nielsen-Kahn, J.,Shastry, M.,Merrill, A.R.,Andersen, G.R. Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2 J.Biol.Chem. 2007 282 657 666 2DWS 17148448 Cu-containing nitrite reductase at pH 8.4 with bound nitrite 2006-08-16 2006-12-05 Jacobson, F.,Pistorius, A.,Farkas, D.,De Grip, W.,Hansson, O.,Sjolin, L.,Neutze, R. pH Dependence of Copper Geometry, Reduction Potential, and Nitrite Affinity in Nitrite Reductase J.Biol.Chem. 2007 282 6347 6355 2DWT 17148448 Cu-containing nitrite reductase at pH 6.0 with bound nitrite 2006-08-17 2006-12-05 Jacobson, F.,Pistorius, A.,Farkas, D.,De Grip, W.,Hansson, O.,Sjolin, L.,Neutze, R. pH Dependence of Copper Geometry, Reduction Potential, and Nitrite Affinity in Nitrite Reductase J.Biol.Chem. 2007 282 6347 6355 2JAC 17327665 Glutaredoxin Grx1p C30S mutant from yeast 2006-11-27 2006-12-11 Hakansson, K.O.,Winther, J.R. Structure of Glutaredoxin Grx1P C30S Mutant from Yeast. Acta Crystallogr.,Sect.D 2007 63 288 0 2C92 16984393 LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) PENTANE 1 PHOSPHATE 2005-12-09 2006-12-13 Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J. 2006 273 4790 0 2JAD 17327665 Yellow fluorescent protein - glutaredoxin fusion protein 2006-11-27 2006-12-20 Hakansson, K.O.,Winther, J.R. Structure of Glutaredoxin Grx1P C30S Mutant from Yeast. Acta Crystallogr.,Sect.D 2007 63 288 0 2GBT 17070542 C6A/C111A CuZn Superoxide dismutase 2006-03-11 2007-01-02 Hornberg, A.,Logan, D.T.,Marklund, S.L.,Oliveberg, M. 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The Isomerase Domain of Human Gfpt1 in Complex with Fructose 6-Phosphate To be Published 0 0 0 0 2VDI 18072944 Crystal structure of Chlamydomonas reinhardtii Rubisco with a large- subunit C192S mutation 2007-10-09 2008-11-04 Garcia-Murria, M.-J.,Karkehabadi, S.,Marin-Navarro, J.,Satagopan, S.,Andersson, I.,Spreitzer, R.J.,Moreno, J. Structural and Functional Consequences of the Replacement of Proximal Residues Cys-172 and Cys-192 in the Large Subunit of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase from Chlamydomonas Reinhardtii Biochem.J. 2008 411 241 0 3DL4 18975951 Non-Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update 2008-06-26 2008-12-02 Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F. Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation. 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An anti-epidermal growth factor receptor antibody 2009-03-11 2009-08-04 Talavera, A.,Friemann, R.,Gomez-Puerta, S.,Martinez-Fleites, C.,Garrido, G.,Rabasa, A.,Lopez-Requena, A.,Pupo, A.,Johansen, R.F.,Sanchez, O.,Krengel, U.,Moreno, E. Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation Cancer Res. 2009 69 5851 5859 3GKW 19584289 Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody 2009-03-11 2009-08-04 Talavera, A.,Friemann, R.,Gomez-Puerta, S.,Martinez-Fleites, C.,Garrido, G.,Rabasa, A.,Lopez-Requena, A.,Pupo, A.,Johansen, R.F.,Sanchez, O.,Krengel, U.,Moreno, E. 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Biochemistry 2011 50 5507 0 3ZS0 21880720 Human Myeloperoxidase inactivated by TX2 2011-06-21 2011-08-31 Tiden, A.K.,Sjogren, T.,Svensson, M.,Bernlind, A.,Senthilmohan, R.,Auchere, F.,Norman, H.,Markgren, P.O.,Gustavsson, S.,Schmidt, S.,Lundquist, S.,Forbes, L.V.,Magon, N.J.,Paton, L.N.,Jameson, G.N.,Eriksson, H.,Kettle, A.J. 2-Thioxanthines are Mechanism-Based Inactivators of Myeloperoxidase that Block Oxidative Stress During Inflammation. J.Biol.Chem. 2011 286 37578 0 3PZE 22551018 JNK1 in complex with inhibitor 2010-12-14 2011-12-14 Oza, V.,Ashwell, S.,Almeida, L.,Brassil, P.,Breed, J.,Deng, C.,Gero, T.,Grondine, M.,Horn, C.,Ioannidis, S.,Liu, D.,Lyne, P.,Newcombe, N.,Pass, M.,Read, J.,Ready, S.,Rowsell, S.,Su, M.,Toader, D.,Vasbinder, M.,Yu, D.,Yu, Y.,Xue, Y.,Zabludoff, S.,Janetka, J. Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas. 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Crystal Structure of Core-Bradavidin To be Published 0 0 0 0 4C4C 24341799 Michaelis complex of Hypocrea jecorina CEL7A E217Q mutant with cellononaose spanning the active site 2013-09-05 2014-01-08 Knott, B.C.,Haddad Momeni, M.,Crowley, M.F.,Mackenzie, L.F.,Gotz, A.W.,Sandgren, M.,Withers, S.G.,Stahlberg, J.,Beckham, G.T. The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies. J.Am.Chem.Soc. 2014 136 321 0 4UX6 21398123 The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) 2014-08-19 2014-10-08 Cheshire, D.R.,Aberg, A.,Andersson, G.M.K.,Andrews, G.,Beaton, H.G.,Birkinshaw, T.N.,Boughton-Smith, N.,Connolly, S.,Cook, T.R.,Cooper, A.,Cooper, S.L.,Cox, D.,Dixon, J.,Gensmantel, N.,Hamley, P.J.,Harrison, R.,Hartopp, P.,Kack, H.,Leeson, P.D.,Luker, T.,Mete, A.,Millichip, I.,Nicholls, D.J.,Pimm, A.D.,St-Gallay, S.A.,Wallace, A.V. 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