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Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography J.Biol.Chem. 2003 278 7300 7309 1MZG 15522304 X-Ray Structure of SufE from E.coli Northeast Structural Genomics (NESG) Consortium Target ER30 2002-10-07 2003-01-28 Goldsmith-Fischman, S.,Kuzin, A.,Edstrom, W.C.,Benach, J.,Shastry, R.,Xiao, R.,Acton, T.B.,Honig, B.,Montelione, G.T.,Hunt, J.F. The SufE sulfur-acceptor protein contains a conserved core structure that mediates interdomain interactions in a variety of redox protein complexes J.Mol.Biol. 2004 344 549 565 1NDB 12526798 Crystal structure of Carnitine Acetyltransferase 2002-12-09 2003-01-28 Jogl, G.,Tong, L. Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.) 2003 112 113 122 1NDF 12526798 Carnitine Acetyltransferase in Complex with Carnitine 2002-12-09 2003-01-28 Jogl, G.,Tong, L. Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.) 2003 112 113 122 1NDI 12526798 Carnitine Acetyltransferase in complex with CoA 2002-12-09 2003-01-28 Jogl, G.,Tong, L. Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.) 2003 112 113 122 1NEP 12591954 Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein 2002-12-11 2003-01-28 Friedland, N.,Liou, H.-L.,Lobel, P.,Stock, A.M. Structure of a Cholesterol-binding Protein Deficient in Niemann-Pick Type C2 Disease Proc.Natl.Acad.Sci.USA 2003 100 2512 2517 1MM7 12501192 Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Quisqualate in a Zinc Crystal Form at 1.65 Angstroms Resolution 2002-09-03 2003-02-04 Jin, R.,Horning, M.,Mayer, M.L.,Gouaux, E. Mechanism of Activation and Selectivity in a Ligand-Gated Ion Channel: Structural and Functional Studies of GluR2 and Quisqualate Biochemistry 2003 41 15635 15643 1NJU 12549906 Complex structure of HCMV Protease and a peptidomimetic inhibitor 2003-01-02 2003-02-11 Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry 2003 42 885 891 1NKM 12549906 Complex structure of HCMV Protease and a peptidomimetic inhibitor 2003-01-03 2003-02-11 Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry 2003 42 885 891 1NUN 12591959 Crystal Structure Analysis of the FGF10-FGFR2b Complex 2003-01-31 2003-02-11 Yeh, B.K.,Igarashi, M.,Eliseenkova, A.V.,Plotnikov, A.N.,Sher, I.,Ron, D.,Aaronson, S.A.,Mohammadi, M. Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. Proc.Natl.Acad.Sci.USA 2003 100 2266 2271 1N8Y 12610629 Crystal structure of the extracellular region of rat HER2 2002-11-21 2003-02-18 Cho, H.-S.,Mason, K.,Ramyar, K.X.,Stanley, A.M.,Gabelli, S.B.,Denney Jr., D.W.,Leahy, D.J. Structure of the Extracellular Region of HER2 Alone and in complex with the Herceptin Fab Nature 2003 421 756 760 1N8Z 12610629 Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab 2002-11-21 2003-02-18 Cho, H.-S.,Mason, K.,Ramyar, K.X.,Stanley, A.M.,Gabelli, S.B.,Denney Jr., D.W.,Leahy, D.J. Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab Nature 2003 421 756 760 1NXZ 14517985 X-Ray Crystal Structure of Protein yggj_haein of Haemophilus influenzae. Northeast Structural Genomics Consortium Target IR73. 2003-02-11 2003-03-11 Forouhar, F.,Shen, J.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L. Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot. Proteins 2003 53 329 332 1ON0 Crystal Structure of Putative Acetyltransferase (YycN) from Bacillus subtilis, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR144 2003-02-26 2003-03-11 Forouhar, F.,Shen, J.,Kuzin, A.,Chiang, Y.,Xiao, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L. Crystal Structure of Putative Acetyltransferase (YycN) from Bacillus subtilis To be Published 0 0 0 0 1NY1 CRYSTAL STRUCTURE OF B. SUBTILIS POLYSACCHARIDE DEACETYLASE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR127. 2003-02-11 2003-03-18 Forouhar, F.,Edstrom, W.,Khan, J.,Ma, L.,Chiang, Y.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of Polysaccharide Deacetylase (PDAA_BACSU) from B. Subtilis (Pdaa_Bacsu) Northeast Structural Genomics Research Consortium (Nesg) Target Sr127 To be Published 0 0 0 0 1NT2 12598892 CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX 2003-01-28 2003-04-01 Aittaleb, M.,Rashid, R.,Chen, Q.,Palmer, J.R.,Daniels, C.J.,Li, H. Structure and function of archaeal box C/D sRNP core proteins. Nat.Struct.Biol. 2003 10 256 263 1OD2 12663926 Acetyl-CoA Carboxylase Carboxyltransferase Domain 2003-02-12 2003-04-03 Zhang, H.,Yang, Z.,Shen, Y.,Tong, L. Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science 2003 299 2064 2067 1OD4 12663926 Acetyl-CoA Carboxylase Carboxyltransferase Domain 2003-02-12 2003-04-03 Zhang, H.,Yang, Z.,Shen, Y.,Tong, L. Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science 2003 299 2064 2067 1MHP 12662928 Crystal structure of a chimeric alpha1 integrin I-domain in complex with the Fab fragment of a humanized neutralizing antibody 2002-08-20 2003-04-15 Karpusas, M.,Ferrant, J.,Weinreb, P.,Carmillo, A.,Taylor, F.,Garber, E. Crystal Structure of the alpha 1 beta 1 Integrin I Domain in Complex with an Antibody Fab Fragment J.Mol.Biol. 2003 327 1031 1041 1N8F 12667068 Crystal structure of E24Q mutant of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Escherichia Coli in complex with Mn2+ and PEP 2002-11-20 2003-04-22 Shumilin, I.A.,Bauerle, R.,Kretsinger, R.H. The High-Resolution Structure of 3-Deoxy-D-arabino-heptulosonate-7-phosphate Synthase Reveals a Twist in the Plane of Bound Phosphoenolpyruvate Biochemistry 2003 42 3766 3776 1P1M Structure of Thermotoga maritima amidohydrolase TM0936 bound to Ni and methionine 2003-04-12 2003-04-29 Kniewel, R.,Buglino, J.A.,Lima, C.D. Structure of the hypothetical protein TM0936 from Thermotoga maritima at 1.5A bound to Ni and methionine To be Published 2003 0 0 0 1P2F 12837793 Crystal Structure Analysis of Response Regulator DrrB, a Thermotoga maritima OmpR/PhoB Homolog 2003-04-15 2003-04-29 Robinson, V.L.,Wu, T.,Stock, A.M. Structural analysis of the domain interface in DrrB, a response regulator of the OmpR/PhoB subfamily J.Bacteriol. 2003 185 4186 4194 1P4K 12906830 CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT 2003-04-23 2003-05-06 Qian, X.,Guan, C.,Guo, H.C. A dual role for an aspartic acid in glycosylasparaginase autoproteolysis. Structure 2003 11 997 1003 1C80 REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE 2000-04-03 2003-06-10 Lee, Y.-H.,Olson, T.W.,McClard, R.W.,Witte, J.F.,McFarlan, S.C.,Banaszak, L.J.,Levitt, D.G.,Lange, A.J. Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published 0 0 0 0 1C81 MICHAELIS COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE 2000-04-03 2003-06-10 Lee, Y.-H.,Olson, T.W.,McClard, R.W.,Witte, J.F.,McFarlan, S.C.,Banaszak, L.J.,Levitt, D.G.,Lange, A.J. Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published 0 0 0 0 1MXU 12731861 CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MXV 12731861 crystal titration experiments (AMPA co-crystals soaked in 10 mM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MXW 12731861 crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry 2003 42 5201 5213 1MXX 12731861 crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MXY 12731861 crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry 2003 42 5201 5213 1MXZ 12731861 crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry 2003 42 5201 5213 1MY0 12731861 crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MY1 12731861 crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MY2 12731861 crystal titration experiment (AMPA complex control) 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry 2003 42 5201 5213 1MY3 12731861 crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1MY4 12731861 crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form 2002-10-03 2003-06-10 Jin, R.,Gouaux, E. Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry 2003 42 5201 5213 1P1N 12730367 GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate 2003-04-13 2003-06-10 Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA 2003 100 5736 5741 1P1O 12730367 Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate 2003-04-13 2003-06-10 Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA 2003 100 5736 5741 1P1Q 12730367 Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA 2003-04-13 2003-06-10 Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA 2003 100 5736 5741 1P1U 12730367 Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form) 2003-04-14 2003-06-10 Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA 2003 100 5736 5741 1P1W 12730367 Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA 2003-04-14 2003-06-10 Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA 2003 100 5736 5741 1F30 THE STRUCTURAL BASIS FOR DNA PROTECTION BY E. COLI DPS PROTEIN 2000-05-31 2003-06-17 Luo, J.,Liu, D.,White, M.A.,Fox, R.O. The Structural Basis for DNA Protection by E. coli Dps Protein To be Published 0 0 0 0 1I6X STRUCTURE OF A STAR MUTANT CRP-CAMP AT 2.2 A 2001-03-06 2003-06-17 White, M.A.,Liu, D.,Lin, S.-H.,Fox, R.O.,Lee, J.C. The effect of the D53H point mutation on the macroscopic motions of E. coli Cyclic AMP Receptor Protein To be Published 0 0 0 0 1PB7 12805203 CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION 2003-05-14 2003-06-24 Furukawa, H.,Gouaux, E. Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J. 2003 22 2873 2885 1PB8 12805203 CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION 2003-05-14 2003-06-24 Furukawa, H.,Gouaux, E. Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J. 2003 22 2873 2885 1PB9 12805203 CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION 2003-05-14 2003-06-24 Furukawa, H.,Gouaux, E. Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J. 2003 22 2873 2885 1PDV 12761214 Crystal structure of human DJ-1, P 31 2 1 space group 2003-05-20 2003-06-24 Tao, X.,Tong, L. Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease. J.Biol.Chem. 2003 278 31372 31379 1PDW 12761214 Crystal structure of human DJ-1, P 1 21 1 space group 2003-05-20 2003-06-24 Tao, X.,Tong, L. Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease. J.Biol.Chem. 2003 278 31372 31379 1PE0 12761214 Crystal structure of the K130R mutant of human DJ-1 2003-05-20 2003-06-24 Tao, X.,Tong, L. Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease. J.Biol.Chem. 2003 278 31372 31379 1NUX 12595528 Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and inhibitory concentrations of Potassium (200mM) 2003-02-01 2003-07-08 Choe, J.Y.,Iancu, C.V.,Fromm, H.J.,Honzatko, R.B. Metaphosphate in the active site of fructose-1,6-bisphosphatase J.BIOL.CHEM. 2003 278 16015 16020 1NV0 12595529 Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and 1 mM Thallium 2003-02-01 2003-07-08 Choe, J.Y.,Nelson, S.W.,Fromm, H.J.,Honzatko, R.B. Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase J.BIOL.CHEM. 2003 278 16008 16014 1PQW Putative enoyl reductase domain of polyketide synthase 2003-06-19 2003-07-08 Gogos, A.,Mu, H.,Shapiro, L. Putative enoyl reductase domain of polyketide synthase To be Published 0 0 0 0 1PUJ Structure of B. subtilis YlqF GTPase 2003-06-24 2003-07-08 Kniewel, R.,Buglino, J.,Lima, C.D. Structure of the YlqF GTPase from B. subtilis To be Published 0 0 0 0 1LXJ 12866058 X-RAY STRUCTURE OF YBL001c NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYst72 2002-06-05 2003-07-29 Tao, X.,Khayat, R.,Christendat, D.,Savchenko, A.,Xu, X.,Goldsmith-Fischman, S.,Honig, B.,Edwards, A.,Arrowsmith, C.H.,Tong, L. CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C Proteins 2003 52 478 480 1LXN 12866058 X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 2002-06-05 2003-07-29 Tao, X.,Khayat, R.,Christendat, D.,Savchenko, A.,Xu, X.,Goldsmith-Fischman, S.,Honig, B.,Edwards, A.,Arrowsmith, C.H.,Tong, L. Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C Proteins 2003 52 478 480 1PBQ 12805203 CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION 2003-05-14 2003-07-29 Furukawa, H.,Gouaux, E. Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core Embo J. 2003 22 2873 2885 1MQI 12872125 Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution 2002-09-16 2003-08-05 Jin, R.,Banke, T.G.,Mayer, M.L.,Traynelis, S.F.,Gouaux, E. Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci. 2003 6 803 810 1Q1U 12815063 Crystal structure of human FHF1b (FGF12b) 2003-07-22 2003-08-05 Olsen, S.K.,Garbi, M.,Zampieri, N.,Eliseenkova, A.V.,Ornitz, D.M.,Goldfarb, M.,Mohammadi, M. 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Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag Mol.Cell 2003 12 365 372 1OU9 14536076 Structure of SspB, a AAA+ protease delivery protein 2003-03-24 2003-09-23 Levchenko, I.,Grant, R.A.,Wah, D.A.,Sauer, R.T.,Baker, T.A. Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag Mol.Cell 2003 12 365 372 1OUL 14536076 Structure of the AAA+ protease delivery protein SspB 2003-03-24 2003-09-23 Levchenko, I.,Grant, R.A.,Wah, D.A.,Sauer, R.T.,Baker, T.A. Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag Mol.Cell 2003 12 365 372 1LLM 14621985 Crystal Structure of a Zif23-GCN4 Chimera Bound to DNA 2002-04-29 2003-09-30 Wolfe, S.A.,Grant, R.A.,Pabo, C.O. Structure of a designed dimeric zinc finger protein bound to DNA. Biochemistry 2003 42 13401 13409 1Q12 14527411 Crystal Structure of the ATP-bound E. coli MalK 2003-07-18 2003-09-30 Chen, J.,Lu, G.,Lin, J.,Davidson, A.L.,Quiocho, F.A. A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell 2003 12 651 661 1Q1B 14527411 Crystal structure of E. coli MalK in the nucleotide-free form 2003-07-18 2003-09-30 Chen, J.,Lu, G.,Lin, J.,Davidson, A.L.,Quiocho, F.A. A tweezer-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell 2003 12 651 661 1Q1E 14527411 The ATPase component of E. coli maltose transporter (MalK) in the nucleotide-free form 2003-07-19 2003-09-30 Chen, J.,Lu, G.,Lin, J.,Davidson, A.L.,Quiocho, F.A. A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell 2003 12 651 661 1PRW 14527397 Crystal structure of bovine brain Ca++ calmodulin in a compact form 2003-06-20 2003-10-10 Fallon, J.L.,Quiocho, F.A. A closed compact structure of native ca(2+)-calmodulin. Structure 2003 11 1303 1307 1G8S METHANOCOCCUS JANNASCHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN 2000-11-20 2003-10-14 Boisvert, D.C.,Kim, S.H. A Structural Approach to Gene Function and Structure Quality for Pyrococcus horikshii Fibrillarin To be Published 0 0 0 0 1R0O 14592980 Crystal Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex 2003-09-22 2003-10-21 Devarakonda, S.,Harp, J.M.,Kim, Y.,Ozyhar, A.,Rastinejad, F. Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex Embo J. 2003 22 5827 5840 1PJ2 12962632 Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate 2003-05-30 2003-11-11 Tao, X.,Yang, Z.,Tong, L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure 2003 11 1141 1150 1PJ3 12962632 Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate. 2003-05-30 2003-11-11 Tao, X.,Yang, Z.,Tong, L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure 2003 11 1141 1150 1PZ5 14645714 Structural basis of peptide-carbohydrate mimicry in an antibody combining site 2003-07-09 2003-11-18 Vyas, N.K.,Vyas, M.N.,Chervenak, M.C.,Bundle, D.R.,Pinto, B.M.,Quiocho, F.A. Structural basis of peptide-carbohydrate mimicry in an antibody combining site. Proc.Natl.Acad.Sci.USA 2003 100 15023 15028 1R5L 14657365 Crystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligand 2003-10-10 2003-11-25 Min, K.C.,Kovall, R.A.,Hendrickson, W.A. Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency Proc.Natl.Acad.Sci.USA 2003 100 14713 14718 1R5L 14657365 Crystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligand 2003-10-10 2003-11-25 Min, K.C.,Kovall, R.A.,Hendrickson, W.A. Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency Proc.Natl.Acad.Sci.USA 2003 100 14713 14718 1RI6 Structure of a putative isomerase from E. coli 2003-11-16 2003-11-25 Lima, C.D.,Kniewel, R.,Solorzano, V.,Wu, J. Structure of a putative 7-bladed propeller isomerase To be Published 0 0 0 0 1D01 10518213 STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A HUMAN CD30 PEPTIDE 1999-09-07 2003-12-02 Ye, H.,Park, Y.C.,Kreishman, M.,Kieff, E.,Wu, H. The structural basis for the recognition of diverse receptor sequences by TRAF2. Mol.Cell 1999 4 321 330 1QYI X-RAY STRUCTURE OF Q8NW41 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR25. 2003-09-10 2003-12-02 Kuzin, A.P.,Edstrom, W.,Ma, L.C.,Shih, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-RAY STRUCTURE OF Q8NW41 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR25. To be Published 0 0 0 0 1RCU X-RAY STRUCTURE OF TM1055 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET VT76 2003-11-04 2003-12-02 Kuzin, A.P.,Edwards, A.,Skarina, T.,Savchenko, A.,Tong, L. X-RAY STRUCTURE OF TM1055 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET VT76 TO BE PUBLISHED 0 0 0 0 1C3H ACRP30 CALCIUM COMPLEX 1999-07-27 2003-12-09 Boggon, T.,Scherer, P.,Shapiro, L. ACRP30 calcium complex To Be Published 0 0 0 0 1RPY 14690593 CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS 2003-12-03 2003-12-23 Hu, J.,Liu, J.,Ghirlando, R.,Saltiel, A.R.,Hubbard, S.R. Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell 2003 12 1379 1389 1RTY 17588214 Crystal Structure of Bacillus subtilis YvqK, a putative ATP-binding Cobalamin Adenosyltransferase, The North East Structural Genomics Target SR128 2003-12-10 2003-12-23 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM. 2007 8 37 44 1S20 14718529 A novel NAD binding protein revealed by the crystal structure of E. Coli 2,3-diketogulonate reductase (YiaK) NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82 2004-01-07 2004-01-20 Forouhar, F.,Lee, I.,Benach, J.,Kulkarni, K.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L. A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK). J.Biol.Chem. 2004 279 13148 13155 1Q4C 14684834 S65T Q80R T203C Green Fluorescent Protein (GFP) pH 8.5 2003-08-02 2004-02-03 Jain, R.K.,Ranganathan, R. Local complexity of amino acid interactions in a protein core. Proc.Natl.Acad.Sci.USA 2004 101 111 116 1RZ7 14981267 CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D 2003-12-24 2004-02-03 Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA 2004 101 2706 2711 1RZF 14981267 Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51 2003-12-24 2004-02-03 Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA 2004 101 2706 2711 1RZG 14981267 Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d 2003-12-24 2004-02-03 Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA 2004 101 2706 2711 1RZJ 14981267 HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B 2003-12-24 2004-02-03 Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA 2004 101 2706 2711 1RZK 14981267 HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B 2003-12-24 2004-02-03 Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA 2004 101 2706 2711 1RY7 14732692 Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 2003-12-19 2004-02-10 Olsen, S.K.,Ibrahimi, O.A.,Raucci, A.,Zhang, F.,Eliseenkova, A.V.,Yayon, A.,Basilico, C.,Linhardt, R.J.,Schlessinger, J.,Mohammadi, M. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proc.Natl.Acad.Sci.Usa 2004 101 935 940 1R6K 14634007 HPV11 E2 TAD crystal structure 2003-10-15 2004-02-24 Wang, Y.,Coulombe, R.,Cameron, D.R.,Thauvette, L.,Massariol, M.-J.,Amon, L.M.,Fink, D.,Titolo, S.,Welchner, E.,Yoakim, C.,Archambault, J.,White, P.W. Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor J.Biol.Chem. 2004 279 6976 6985 1S68 14962393 Structure and Mechanism of RNA Ligase 2004-01-22 2004-02-24 Ho, C.K.,Wang, L.K.,Lima, C.D.,Shuman, S. Structure and mechanism of RNA ligase. Structure 2004 12 327 339 1SBK X-RAY STRUCTURE OF YDII_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER29. 2004-02-10 2004-02-24 Kuzin, A.P.,Edstrom, W.,Vorobiev, S.M.,Lee, I.,Forouhar, F.,Ma, L.,Chiang, Y.,Rong, X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray Structure of YDII_ECOLI Northeast Structural Genomics Consortium Target ER29 To be Published 0 0 0 0 1SDJ 15545603 X-RAY STRUCTURE OF YDDE_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ET25. 2004-02-13 2004-02-24 Blankenfeldt, W.,Kuzin, A.P.,Skarina, T.,Korniyenko, Y.,Tong, L.,Bayer, P.,Janning, P.,Thomashow, L.S.,Mavrodi, D.V. Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens. Proc.Natl.Acad.Sci.Usa 2004 101 16431 16436 1RY2 14769018 Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP 2003-12-19 2004-03-09 Jogl, G.,Tong, L. Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP Biochemistry 2004 43 1425 1431 1S1D 15006348 Structure and protein design of human apyrase 2004-01-06 2004-03-16 Dai, J.,Liu, J.,Deng, Y.,Smith, T.M.,Lu, M. Structure and protein design of a human platelet function inhibitor. Cell(Cambridge,Mass.) 2004 116 649 659 1OT7 12718893 Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR 2003-03-21 2004-03-23 Mi, L.Z.,Devarakonda, S.,Harp, J.M.,Han, Q.,Pellicciari, R.,Willson, T.M.,Khorasanizadeh, S.,Rastinejad, F. Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR Mol.Cell 2003 11 1093 1100 1UYR 15079078 Acetyl-CoA Carboxylase Carboxyltransferase Domain in complex with inhibitor Diclofop 2004-03-02 2004-03-29 Zhang, H.,Tweel, B.,Tong, L. Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA 2004 101 5910 0 1UYS 15079078 Acetyl-CoA carboxylase carboxyltransferase domain in complex with inhibitor haloxyfop 2004-03-02 2004-03-29 Zhang, H.,Tweel, B.,Tong, L. Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA 2004 101 5910 0 1UYT 15079078 Acetyl-CoA carboxylase carboxyltransferase domain 2004-03-02 2004-03-29 Zhang, H.,Tweel, B.,Tong, L. Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop. Proc.Natl.Acad.Sci.USA 2004 101 5910 0 1UYV 15079078 Acetyl-CoA carboxylase carboxyltransferase domain L1705I/V1967I mutant 2004-03-02 2004-03-29 Zhang, H.,Tweel, B.,Tong, L. Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop Proc.Natl.Acad.Sci.USA 2004 101 5910 0 1SC0 X-ray Structure of YB61_HAEIN Northeast Structural Genomics Consortium Target IR63 2004-02-11 2004-03-30 Kuzin, A.P.,Lee, I.,Chiang, Y.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray Structure of YB61_HAEIN Northeast Structural Genomics Consortium Target IR63. To be Published 0 0 0 0 1SQS 17588214 X-Ray Crystal Structure Protein SP1951 of Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR27. 2004-03-19 2004-03-30 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM 2007 8 37 44 1SPV Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58 2004-03-17 2004-04-06 Forouhar, F.,Lee, I.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58 To be Published 0 0 0 0 1SQ1 Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast Structural Genomics Target BR19 2004-03-17 2004-04-06 Forouhar, F.,Lee, I.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast Structural Genomics Target BR19 To be Published 0 0 0 0 1SQ4 Crystal Structure of the Putative Glyoxylate Induced Protein from Pseudomonas aeruginosa, Northeast Structural Genomics Target PaR14 2004-03-17 2004-04-06 Forouhar, F.,Chen, Y.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Glyoxylate Induced Protein from Pseudomonas aeruginosa, Northeast Structural Genomics Target PaR14 To be Published 0 0 0 0 1SQH X-RAY STRUCTURE OF DROSOPHILA MALONOGASTER PROTEIN Q9VR51 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR87. 2004-03-18 2004-04-06 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Acton, T.B.,Xiao, R.,Cooper, B.,Ho, C.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-RAY STRUCTURE OF DROSOPHILA MALONOGASTER PROTEIN Q9VR51 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR87 To be Published 0 0 0 0 1ST4 15068804 Structure of DcpS bound to m7GpppA 2004-03-24 2004-04-13 Gu, M.,Fabrega, C.,Liu, S.W.,Liu, H.,Kiledjian, M.,Lima, C.D. Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity Mol.Cell 2004 14 67 80 1SDW 15131304 Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen 2004-02-14 2004-05-11 Prigge, S.T.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex. Science 2004 304 864 867 1T3H X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57 2004-04-26 2004-05-11 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Edstrom, W.,Benach, J.,Vorobiev, S.,Acton, T.,Shastry, R.,Ma, L.-C.,Xia, R.,Montelione, G.,Tong, L.,Hunt, J. X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57 TO BE PUBLISHED 0 0 0 0 1T82 Crystal Structure of the putative thioesterase from Shewanella oneidensis, Northeast Structural Genomics Target SoR51 2004-05-11 2004-05-18 Forouhar, F.,Lee, I.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the putative thioesterase from Shewanella oneidensis, Northeast Structural Genomics Target SoR51 TO BE PUBLISHED 0 0 0 0 1Q9J 15123643 Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis 2003-08-25 2004-05-25 Buglino, J.,Onwueme, K.C.,Ferreras, J.A.,Quadri, L.E.,Lima, C.D. Crystal Structure of PapA5, a Phthiocerol Dimycocerosyl Transferase from Mycobacterium tuberculosis J.Biol.Chem. 2004 279 30634 30642 1T5Y Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p 2004-05-05 2004-06-01 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Acton, T.B.,Shastry, R.,Ma, L.-C.,Cooper, B.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J.F. Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p To be Published 0 0 0 0 1RFX 15155948 Crystal Structure of resisitin 2003-11-10 2004-06-08 Patel, S.D.,Rajala, M.W.,Rossetti, L.,Scherer, P.E.,Shapiro, L. Disulfide-dependent multimeric assembly of resistin family hormones Science 2004 304 1154 1158 1RH7 15155948 Crystal Structure of Resistin-like beta 2003-11-13 2004-06-08 Patel, S.D.,Rajala, M.W.,Rossetti, L.,Scherer, P.E.,Shapiro, L. Disulfide-dependent multimeric assembly of resistin family hormones Science 2004 304 1154 1158 1VYT 15170217 beta3 subunit complexed with aid 2004-05-07 2004-06-15 Chen, Y.-H.,Li, M.-H.,Zhang, Y.,He, L.-L.,Yamada, Y.,Fitzmaurice, A.,Shen, Y.,Zhang, H.,Tong, L.,Yang, J. Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels Nature 2004 429 675 0 1VYU 15170217 Beta3 subunit of Voltage-gated Ca2+-channel 2004-05-07 2004-06-15 Chen, Y.-H.,Li, M.-H.,Zhang, Y.,He, L.-L.,Yamada, Y.,Fitzmaurice, A.,Shen, Y.,Zhang, H.,Tong, L.,Yang, J. Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels Nature 2004 429 675 0 1VYV 15170217 beta4 subunit of Ca2+ channel 2004-05-07 2004-06-15 Chen, Y.-H.,Li, M.-H.,Zhang, Y.,He, L.-L.,Yamada, Y.,Fitzmaurice, A.,Shen, Y.,Zhang, H.,Tong, L.,Yang, J. Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels Nature 2004 429 675 0 1T7N 15155726 Crystal structure of the M564G mutant of murine CrAT 2004-05-10 2004-06-22 Hsiao, Y.-S.,Jogl, G.,Tong, L. Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase J.Biol.Chem. 2004 279 31584 31589 1T7Q 15155726 Crystal structure of the F565A mutant of murine carnitine acetyltransferase in complex with carnitine and CoA 2004-05-10 2004-06-22 Hsiao, Y.-S.,Jogl, G.,Tong, L. Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase J.Biol.Chem. 2004 279 31584 31589 1TIY X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160 2004-06-02 2004-06-22 Kuzin, A.P.,Vorobiev, S.,Edstrom, W.,Forouhar, F.,Acton, T.,Shastry, R.,Ma, L.-C.,Chiang, Y.-W.,Montelione, G.,Tong, L.,Hunt, J.F. X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160 To be published 0 0 0 0 1TLT Crystal Structure of a Putative Oxidoreductase (VIRULENCE FACTOR mviM HOMOLOG) 2004-06-09 2004-06-22 RAJASHANKAR, K.R.,SOLORZANO, V.,KNIEWEL, R.,LIMA, C.D. Crystal Structure of a Putative Oxidoreductase (VIRULENCE FACTOR mviM HOMOLOG) To be Published 0 0 0 0 1TM0 17588214 Crystal Structure of the putative proline racemase from Brucella melitensis, Northeast Structural Genomics Target LR31 2004-06-10 2004-06-29 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM. 2007 8 37 44 1TIQ 16210326 Crystal Structure of an Acetyltransferase (PaiA) in complex with CoA and DTT from Bacillus subtilis, Northeast Structural Genomics Target SR64. 2004-06-02 2004-07-13 Forouhar, F.,Lee, I.S.,Vujcic, J.,Vujcic, S.,Shen, J.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Porter, C.W.,Tong, L. Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase. J.Biol.Chem. 2005 280 40328 40336 1TTZ X-ray structure of Northeast Structural Genomics target protein XcR50 from X. campestris 2004-06-23 2004-07-13 Kuzin, A.P.,Vorobiev, S.M.,Lee, I.,Edstrom, W.,Acton, T.B.,Ho, C.K.,Cooper, B.,Ma, L.-C.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J.F. X-ray structure of Northeast Structural Genomics target protein XcR50 from X. campestris To be Published 0 0 0 0 1TO0 X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis 2004-06-11 2004-07-20 Kuzin, A.P.,Edstrom, W.,Vorobiev, S.M.,Shastry, R.,Ma, L.-C.,Xiao, R.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray structure of Northeast Structural Genomics target protein sr145 from Bacillus subtilis To be Published 0 0 0 0 1TWD Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33 2004-06-30 2004-07-20 Forouhar, F.,Lee, I.,Vorobiev, S.M.,Ma, L.-C.,Shastry, R.,Conover, K.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33 To be Published 0 0 0 0 1TZ9 Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41 2004-07-09 2004-07-20 Forouhar, F.,Chen, Y.,Xiao, R.,Cooper, B.,Shastry, R.,Acton, T.A.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41 To be Published 0 0 0 0 1TZA X-ray structure of Northeast Structural Genomics Consortium target SoR45 2004-07-09 2004-07-27 Kuzin, A.P.,Vorobiev, S.M.,Edstrom, W.,Acton, T.B.,Shastry, R.,Ma, L.-C.,Cooper, B.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J.F. X-ray structure of Northeast Structural Genomics Consortium target SoR45 To be Published 0 0 0 0 1RZM 15276836 Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) from Thermotoga maritima complexed with Cd2+, PEP and E4P 2003-12-24 2004-08-10 Shumilin, I.A.,Bauerle, R.,Wu, J.,Woodard, R.W.,Kretsinger, R.H. Crystal Structure of the Reaction Complex of 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase from Thermotoga maritima Refines the Catalytic Mechanism and Indicates a New Mechanism of Allosteric Regulation. J.Mol.Biol. 2004 341 455 466 1SZH 15289613 Crystal Structure of C. elegans HER-1 2004-04-05 2004-08-10 Hamaoka, B.Y.,Dann III, C.E.,Geisbrecht, B.V.,Leahy, D.J. Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A. Proc.Natl.Acad.Sci.USA 2004 101 1673 11678 1TTU 15297877 Crystal Structure of CSL bound to DNA 2004-06-23 2004-08-31 Kovall, R.A.,Hendrickson, W.A. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA Embo J. 2004 23 3441 3451 1T2O 15117963 Crystal structure of Se-SrtA, C184-Ala 2004-04-22 2004-09-07 Zong, Y.,Bice, T.W.,Ton-That, H.,Schneewind, O.,Narayana, S.V. Crystal structures of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem. 2004 279 31383 31389 1W2X 15341732 Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186 2004-07-09 2004-09-09 Zhang, H.,Tweel, B.,Li, J.,Tong, L. Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186 Structure 2004 12 1683 0 1TH0 15296745 Structure of human Senp2 2004-05-31 2004-09-14 Reverter, D.,Lima, C.D. A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex Structure 2004 12 1519 1531 1XBF X-RAY STRUCTURE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CAR10 FROM C. ACETOBUTYLICUM 2004-08-30 2004-09-14 Kuzin, A.P.,Chen, Y.,Vorobiev, S.,Yong, W.,Acton, T.,Ho, C.-K.,Conover, K.,Cooper, B.,Ciano, M.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J. X-RAY STRUCTURE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CAR10 FROM C. ACETOBUTYLICUM To be published 0 0 0 0 1XFS X-Ray Crystal Structure of Protein NE0264 from Nitrosomonas europaea. Northeast Structural Genomics Consortium Target NeR5. 2004-09-15 2004-09-28 Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Ciano, M.,Ma, L.-C.,Shastry, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the hypothetical Protein from Nitrosomonas europaea, NESG Target NeR5 To be Published 0 0 0 0 1W0H 15451662 Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP 2004-06-04 2004-09-30 Cheng, Y.,Patel, D. Crystallographic Structure of the Nuclease Domain of 3'Hexo, a Deddh Family Member, Bound to Ramp J.Mol.Biol. 2004 343 305 0 1XL7 15492013 Crystal Structure of Mouse Carnitine Octanoyltransferase 2004-09-30 2004-10-19 Jogl, G.,Hsiao, Y.S.,Tong, L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. J.Biol.Chem. 2005 280 738 744 1XL8 15492013 Crystal structure of mouse carnitine octanoyltransferase in complex with octanoylcarnitine 2004-09-30 2004-10-19 Jogl, G.,Hsiao, Y.S.,Tong, L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. J.Biol.Chem. 2005 280 738 744 1XM3 Crystal structure of Northeast Structural Genomics Target SR156 2004-10-01 2004-10-19 Kuzin, A.,Abashidze, M.,Vorobiev, S.,Forouhar, F.,Acton, T.,Ma, L.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J. Crystal structure of Northeast Structural Genomics Target SR156 To be Published 0 0 0 0 1XMC 15492013 C323M mutant structure of mouse carnitine octanoyltransferase 2004-10-01 2004-10-19 Jogl, G.,Hsiao, Y.S.,Tong, L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. J.Biol.Chem. 2005 280 738 744 1XMD 15492013 M335V mutant structure of mouse carnitine octanoyltransferase 2004-10-01 2004-10-19 Jogl, G.,Hsiao, Y.S.,Tong, L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. J.Biol.Chem. 2005 280 738 744 1XQB X-Ray Structure Of YaeB from Haemophilus influenzae. Northeast Structural Genomics Research Consortium (NESGC)target IR47. 2004-10-11 2004-10-19 Benach, J.,Lee, I.,Forouhar, F.,Kuzin, A.P.,Keller, J.P.,Itkin, A.,Xiao, R.,Acton, T.,Montelione, G.T.,Hunt, J.F. X-Ray Structure Of YaeB from Haemophilus influenzae. Northeast Structural Genomics Research Consortium (NESGC) target IR47. To be Published 0 0 0 0 1XKT 15507492 Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain 2004-09-29 2004-10-26 Chakravarty, B.,Gu, Z.,Chirala, S.S.,Wakil, S.J.,Quiocho, F.A. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc.Natl.Acad.Sci.Usa 2004 101 15567 15572 1XSQ Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81. 2004-10-19 2004-11-02 Kuzin, A.P.,Vorobiev, S.M.,Abashidze, M.,Acton, T.B.,Ma, L.-C.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81. To be Published 0 0 0 0 1TVG 18816799 X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958. 2004-06-29 2004-11-09 Ramelot, T.A.,Raman, S.,Kuzin, A.P.,Xiao, R.,Ma, L.C.,Acton, T.B.,Hunt, J.F.,Montelione, G.T.,Baker, D.,Kennedy, M.A. Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins 2009 75 147 167 1XQ4 Crystal Structure of the Putative ApaA Protein from Bordetella pertussis, Northeast Structural Genomics Target BeR40 2004-10-11 2004-11-09 Forouhar, F.,Yong, W.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative ApaA Protein from Bordetella pertussis, Northeast Structural Genomics Target BeR40 To be Published 0 0 0 0 1XTO Crystal Structure of the Coenzyme PQQ Synthesis Protein (PqqB) from Pseudomonas putida, Northeast Structural Genomics Target PpR6 2004-10-22 2004-11-09 Forouhar, F.,Chen, Y.,Kuzin, A.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Coenzyme PQQ Synthesis Protein (PqqB) from Pseudomonas putida, Northeast Structural Genomics Target PpR6 To be Published 0 0 0 0 1XW8 X-ray structure of putative lactam utilization protein YBGL. Northeast Structural Genomics Consortium target ET90. 2004-10-29 2004-11-09 Kuzin, A.P.,Chen, Y.,Vorobiev, S.M.,Acton, T.B.,Ma, L.-C.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray structure of putative lactam utilization protein YBGL. Northeast Structural Genomics Consortium target ET90. To be Published 0 0 0 0 1XKN Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 2004-09-29 2004-11-16 Forouhar, F.,Befeler, A.R.,Vorobiev, S.M.,Hussain, M.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 To be Published 0 0 0 0 1T8Z 15520380 Atomic Structure of A Novel Tryptophan-Zipper Pentamer 2004-05-13 2004-11-23 Liu, J.,Yong, W.,Deng, Y.,Kallenbach, N.R.,Lu, M. Atomic structure of a tryptophan-zipper pentamer. Proc.Natl.Acad.Sci.USA 2004 101 16156 16161 1XUV X-Ray Crystal Structure of Protein MM0500 from Methanosarcina mazei. Northeast Structural Genomics Consortium Target MaR10. 2004-10-26 2004-11-23 Forouhar, F.,Abashidze, M.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein from Methanosarcina mazei, Northeast Strcutural Genomics Target MaR10 To be Published 0 0 0 0 1XKL 15668381 Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241 2004-09-29 2004-11-30 Forouhar, F.,Yang, Y.,Kumar, D.,Chen, Y.,Fridman, E. Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proc.Natl.Acad.Sci.USA 2005 102 1773 1778 1Y23 Crystal structure of a member of HIT family of proteins from bacillus subtilis 2004-11-19 2004-12-07 Rajashankar, K.R.,Lima, C.D. Crystal structure of a member of HIT family of proteins from bacillus subtilis To be Published 0 0 0 0 1Y65 Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85 2004-12-03 2004-12-14 Gorman, J.,Shapiro, L. Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85 To be Published 0 0 0 0 1WC0 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with alpha, beta-methylene-ATP 2004-11-05 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1WC1 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with Rp- ATPalphaS 2004-11-06 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1WC3 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with alpha, beta-methylene-ATP and Strontium 2004-11-08 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1WC4 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with alpha, beta-methylene-ATP and Europium 2004-11-08 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1WC5 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with alpha, beta-methylene-ATP in presence of bicarbonate 2004-11-08 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1WC6 15619637 Soluble adenylyl cyclase CyaC from S. platensis in complex with Rp- ATPalphaS in presence of bicarbonate 2004-11-08 2004-12-20 Steegborn, C.,Litvin, T.N.,Levin, L.R.,Buck, J.,Wu, H. Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment Nat.Struct.Mol.Biol. 2005 12 32 0 1T77 15554694 Crystal structure of the PH-BEACH domains of human LRBA/BGL 2004-05-08 2004-12-21 Gebauer, D.,Li, J.,Jogl, G.,Shen, Y.,Myszka, D.G.,Tong, L. Crystal Structure of the PH-BEACH Domains of Human LRBA/BGL Biochemistry 2004 43 14873 14880 1XT9 15567417 Crystal Structure of Den1 in complex with Nedd8 2004-10-21 2004-12-21 Reverter, D.,Wu, K.,Erdene, T.G.,Pan, Z.Q.,Wilkinson, K.D.,Lima, C.D. Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1. J.Mol.Biol. 2005 345 141 151 1XX6 X-ray structure of Clostridium acetobutylicum thymidine kinase with ADP. Northeast Structural Genomics Target CAR26. 2004-11-04 2004-12-21 Kuzin, A.P.,Abashidze, M.,Forouhar, F.,Vorobiev, S.M.,Acton, T.B.,Ma, L.-C.,Xiao, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray structure of Clostridium acetobutylicum thymidine kinase with ADP. Northeast Structural Genomics Target CAR26. To be Published 0 0 0 0 1Y7I 15668381 Structural and biochemical studies identify tobacco SABP2 as a methylsalicylate esterase and further implicate it in plant innate immunity, Northeast Structural Genomics Target AR2241 2004-12-08 2004-12-21 Forouhar, F.,Yang, Y.,Kumar, D.,Chen, Y.,Fridman, E.,Park, S.W.,Chiang, Y.,Acton, T.B.,Montelione, G.T.,Pichersky, E.,Klessig, D.F.,Tong, L. Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proc.Natl.Acad.Sci.USA 2005 102 1773 1778 1Y7H 15668381 Structural and biochemical studies identify tobacco SABP2 as a methylsalicylate esterase and further implicate it in plant innate immunity, Northeast Structural Genomics Target AR2241 2004-12-08 2004-12-28 Forouhar, F.,Yang, Y.,Kumar, D.,Chen, Y.,Fridman, E.,Park, S.W.,Chiang, Y.,Acton, T.B.,Montelione, G.T.,Pichersky, E.,Klessig, D.F.,Tong, L. Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proc.Natl.Acad.Sci.Usa 2005 102 1773 1778 1W93 15610732 Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae 2004-10-05 2005-01-04 Shen, Y.,Volrath, S.L.,Weatherly, S.C.,Elich, T.D.,Tong, L. A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell 2004 16 881 0 1W96 15610732 Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A 2004-10-06 2005-01-04 Shen, Y.,Volrath, S.L.,Weatherly, S.C.,Elich, T.D.,Tong, L. A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell 2004 16 881 0 1VZJ 15526038 Structure of the tetramerization domain of acetylcholinesterase: four-fold interaction of a WWW motif with a left-handed polyproline helix 2004-05-20 2005-01-10 Dvir, H.,Harel, M.,Bon, S.,Liu, W.-Q.,Vidal, M.,Garbay, C.,Sussman, J.L.,Massoulie, J.,Silman, I. The Synaptic Acetylcholinesterase Tetramer Assembles Around a Polyproline-II Helix Embo J. 2004 23 4394 0 1WP0 15659396 Human SCO1 2004-08-27 2005-01-18 Williams, J.C.,Sue, C.,Banting, G.S.,Yang, H.,Glerum, D.M.,Hendrickson, W.A.,Schon, E.A. Crystal Structure of Human SCO1: IMPLICATIONS FOR REDOX SIGNALING BY A MITOCHONDRIAL CYTOCHROME c OXIDASE ""ASSEMBLY"" PROTEIN J.Biol.Chem. 2005 280 15202 15211 1YDM X-Ray structure of Northeast Structural Genomics target SR44 2004-12-24 2005-01-18 Kuzin, A.P.,Jianwei, S.,Vorobiev, S.,Acton, T.,Xia, R.,Ma, L.-C.,Montelione, G.,Tong, L.,Hunt, J.F. X-Ray structure of Northeast Structural Genomics target SR44 To be Published 0 0 0 0 1T3G 15123616 Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of human IL-1RAPL 2004-04-26 2005-02-08 Khan, J.A.,Brint, E.K.,O'Neill, L.A.J.,Tong, L. Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL J.Biol.Chem. 2004 279 31664 31670 1YDL Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045. 2004-12-24 2005-02-08 Forouhar, F.,Edstrom, W.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045. To be Published 0 0 0 0 1YPX Crystal Structure of the Putative Vitamin-B12 Independent Methionine Synthase from Listeria monocytogenes, Northeast Structural Genomics Target LmR13 2005-01-31 2005-02-08 Forouhar, F.,Chen, Y.,Benach, J.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of Putative Vitamin-B12 Independent Methionine Synthase from Listeria monocytogenes, Northeast Structural Genomics Target LmR13 To be Published 0 0 0 0 1YGT 15701632 Dynein Light Chain TcTex-1 2005-01-05 2005-02-15 Williams, J.C.,Xie, H.,Hendrickson, W.A. Crystal structure of dynein light chain TcTex-1. J.Biol.Chem. 2005 280 21981 21986 1YGT 15701632 Dynein Light Chain TcTex-1 2005-01-05 2005-02-15 Williams, J.C.,Xie, H.,Hendrickson, W.A. Crystal structure of dynein light chain TcTex-1. J.Biol.Chem. 2005 280 21981 21986 1YVK Crystal Structure of the Bacillis subtilis Acetyltransferase in complex with CoA, Northeast Structural Genomics Target SR237. 2005-02-15 2005-02-22 Forouhar, F.,Yong, W.,Xiao, R.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Bacillis subtilis Acetyltransferase in complex with CoA, Northeast Structural Genomics Target SR237. To be Published 0 0 0 0 1YN3 15691839 Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens 2005-01-23 2005-03-01 Geisbrecht, B.V.,Hamaoka, B.Y.,Perman, B.,Zemla, A.,Leahy, D.J. The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem. 2005 280 17243 17250 1YN4 15691839 Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens 2005-01-23 2005-03-01 Geisbrecht, B.V.,Hamaoka, B.Y.,Perman, B.,Zemla, A.,Leahy, D.J. The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem. 2005 280 17243 17250 1YVW Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus. NESGC target BcR13. 2005-02-16 2005-03-01 Benach, J.,Kuzin, A.P.,Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Shastry, R.,Rong, X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F. Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus at 2.6 A resolution. To be Published 0 0 0 0 1YW4 Crystal Structure of the Succinylglutamate Desuccinylase from Chromobacterium violaceum, Northeast Structural Genomics Target CvR22. 2005-02-17 2005-03-01 Forouhar, F.,Abashidze, M.,Conover, K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Succinylglutamate Desuccinylase from Chromobacterium violaceum, Northeast Structural Genomics Target CvR22. To be Published 0 0 0 0 1YXB Crystal structure of Phosphoribosyl-ATP pyrophosphatase from Streptomyces coelicolor. NESG target RR8. 2005-02-20 2005-03-01 Benach, J.,Kuzin, A.P.,Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Rong, X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F. Crystal structure of Phosphoribosyl-ATP pyrophosphatase from Streptomyces coelicolor. NESG target RR8. To be Published 0 0 0 0 1WYZ X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28 2005-02-21 2005-03-08 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Vorobiev, S.M.,Acton, T.,Ma, L.-C.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28 To be Published 0 0 0 0 1YUD X-ray Crystal Structure of Protein SO0799 from Shewanella oneidensis. Northeast Structural Genomics Consortium Target SoR12. 2005-02-14 2005-03-08 Kuzin, A.P.,Vorobiev, S.,Chen, Y.,Forouhar, F.,Acton, T.,Ma, L.-C.,Xiao, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of hypothetical protein SO0799 from Shewanella oneidensis To be Published 0 0 0 0 1YVH 15737992 Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide 2005-02-15 2005-03-08 Hu, J.,Hubbard, S.R. Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins J.Biol.Chem. 2005 280 18943 18949 1XDL 15733923 Structure of human aldolase B associated with hereditary fructose intolerance (A149P), at 277K 2004-09-07 2005-03-22 Malay, A.D.,Allen, K.N.,Tolan, D.R. Structure of the thermolabile mutant aldolase B, A149P: molecular basis of hereditary fructose intolerance. J.Mol.Biol. 2005 347 135 144 1Z3C 15760890 Encephalitozooan cuniculi mRNA Cap (Guanine-N7) Methyltransferasein complexed with AzoAdoMet 2005-03-11 2005-03-22 Hausmann, S.,Zheng, S.,Fabrega, C.,Schneller, S.W.,Lima, C.D.,Shuman, S. Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis. J.Biol.Chem. 2005 280 20404 20412 1YJ4 15835903 Y305F Trichodiene Synthase 2005-01-13 2005-03-29 Vedula, L.S.,Rynkiewicz, M.J.,Pyun, H.J.,Coates, R.M.,Cane, D.E.,Christianson, D.W. Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants. Biochemistry 2005 44 6153 6163 1YQL 15800616 Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA 2005-02-02 2005-04-05 Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L. Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature 2005 434 612 618 1YQM 15800616 Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA 2005-02-02 2005-04-05 Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L. Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature 2005 434 612 618 1ZBM X-Ray Crystal Structure of Protein AF1704 from Archaeoglobus fulgidus. Northeast Structural Genomics Consortium Target GR62A. 2005-04-08 2005-04-19 0 0 0 0 1ZBO X-Ray Crystal Structure of Protein BPP1347 from Bordetella parapertussis. Northeast Structural Genomics Consortium Target BoR27. 2005-04-08 2005-04-19 Forouhar, F.,Yong, W.,Conover, K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein BPP1347 from Bordetella parapertussis, Northeast Structural Genomics Target BoR27. To be Published 0 0 0 0 1ZBP 17588214 X-Ray Crystal Structure of Protein VPA1032 from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium Target VpR44 2005-04-08 2005-04-19 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM. 2007 8 37 44 1ZBR Crystal Structure of the Putative Arginine Deiminase from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR3 2005-04-08 2005-04-19 Forouhar, F.,Chen, Y.,Kuzin, A.,Conover, K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Arginine Deiminase from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR3 To be Published 0 0 0 0 1ZCE 19191354 X-Ray Crystal Structure of Protein Atu2648 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR33. 2005-04-11 2005-04-19 Bertonati, C.,Punta, M.,Fischer, M.,Yachdav, G.,Forouhar, F.,Zhou, W.,Kuzin, A.P.,Seetharaman, J.,Abashidze, M.,Ramelot, T.A.,Kennedy, M.A.,Cort, J.R.,Belachew, A.,Hunt, J.F.,Tong, L.,Montelione, G.T.,Rost, B. Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins 2009 75 760 773 1YC5 15780941 Sir2-p53 peptide-nicotinamide 2004-12-21 2005-04-26 Avalos, J.L.,Bever, K.M.,Wolberger, C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol.Cell 2005 17 855 868 1Z2Z Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1 2005-03-10 2005-04-26 Forouhar, F.,Yong, W.,Ciano, M.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1 To be Published 0 0 0 0 1ZEE X-Ray Crystal Structure of Protein SO4414 from Shewanella oneidensis. Northeast Structural Genomics Consortium Target SoR52. 2005-04-18 2005-05-03 Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Conover, K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Hypothetical Protein SO4414 from Shewanella oneidensis, NESG Target SoR52 To be Published 0 0 0 0 1Z94 X-Ray Crystal Structure of Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR12. 2005-03-31 2005-05-10 Kuzin, A.,Vorobiev, S.M.,Yong, W.,Forouhar, F.,Xio, R.,Ma, L.-C.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CVR12. To be Published 0 0 0 0 1ZC6 Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum. Northeast Structural Genomics Target Cvr23. 2005-04-11 2005-05-10 Vorobiev, S.M.,Kuzin, A.,Forouhar, F.,Abashidze, M.,Acton, T.B.,Xiao, R.,Ma, L.-C.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum To be Published 0 0 0 0 1ZHV X-ray Crystal Structure Protein Atu0741 from Agobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR8. 2005-04-26 2005-05-10 Vorobiev, S.M.,Kuzin, A.,Abashidze, M.,Forouhar, F.,Xio, R.,Ma, L.-C.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of hypothetical protein Atu071 from Agobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR8. To be Published 0 0 0 0 1ZKD X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 2005-05-02 2005-05-10 Kuzin, A.P.,Yong, W.,Vorobiev, S.M.,Acton, T.,Ma, L.,Xiao, R.,Montelione, G.,Tong, L.,Hunt, J.F. X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 To be Published 0 0 0 0 1XHE 15876365 Crystal structure of the receiver domain of redox response regulator arca 2004-09-18 2005-05-17 Toro-Roman, A.,Mack, T.R.,Stock, A.M. Structural Analysis and Solution Studies of the Activated Regulatory Domain of the Response Regulator ArcA: A Symmetric Dimer Mediated by the alpha4-beta5-alpha5 Face J.Mol.Biol. 2005 349 11 26 1XHE 15876365 Crystal structure of the receiver domain of redox response regulator arca 2004-09-18 2005-05-17 Toro-Roman, A.,Mack, T.R.,Stock, A.M. Structural Analysis and Solution Studies of the Activated Regulatory Domain of the Response Regulator ArcA: A Symmetric Dimer Mediated by the alpha4-beta5-alpha5 Face J.Mol.Biol. 2005 349 11 26 1XHF 15876365 Crystal structure of the bef3-activated receiver domain of redox response regulator arca 2004-09-18 2005-05-17 Toro-Roman, A.,Mack, T.R.,Stock, A.M. Structural Analysis and Solution Studies of the Activated Regulatory Domain of the Response Regulator ArcA: A Symmetric Dimer Mediated by the alpha4-beta5-alpha5 Face J.Mol.Biol. 2005 349 11 26 1ZMB Crystal Structure of the Putative Acetylxylan Esterase from Clostridium acetobutylicum, Northeast Structural Genomics Target CaR6 2005-05-10 2005-05-17 Forouhar, F.,Vorobiev, S.M.,Abashidze, M.,Ciao, M.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Acetylxylan Esterase from Clostridium acetobutylicum, Northeast Structural Genomics Target CaR6 To be Published 0 0 0 0 1ZN6 X-ray Crystal Structure of Protein Q7WLM8 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium Target BoR19. 2005-05-11 2005-05-17 Kuzin, A.P.,Yong, W.,Vorobiev, S.M.,Xiao, R.,Ma, L.-C.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Tong, L. Novel structure of the hypothetical protein Q7WLM8 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium target BoR19. To be Published 0 0 0 0 1ZI0 15897198 A Superhelical Spiral in Escherichia coli DNA Gyrase A C-terminal Domain Imparts Unidirectional Supercoiling Bias 2005-04-26 2005-05-24 Ruthenburg, A.J.,Graybosch, D.M.,Huetsch, J.C.,Verdine, G.L. A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias J.Biol.Chem. 2005 280 26177 26184 1ZNP X-Ray Crystal Structure of Protein Q8U9W0 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR55. 2005-05-11 2005-05-24 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Vorobiev, S.M.,Xiao, R.,Ma, L.-C.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the hypothetical protein Q8U9W0 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium target AtR55. To be Published 0 0 0 0 1ZP6 Crystal Structure of Atu3015, a Putative Cytidylate Kinase from Agrobacterium tumefaciens, Northeast Structural Genomics Target AtR62 2005-05-16 2005-05-24 Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Kuzin, A.,Conover, K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of Atu3015, a Putative Cytidylate Kinase from Agrobacterium tumefaciens, Northeast Structural Genomics Target AtR62 To be Published 0 0 0 0 1ZQ7 X-Ray Crystal Structure of Protein Q8PZK8 from Methanosarcina mazei. Northeast Structural Genomics Consortium Target MaR9. 2005-05-18 2005-05-31 Kuzin, A.P.,Abashidze, M.,Vorobiev, S.M.,Yong, W.,Xiao, R.,Ma, L.-C.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J. X-Ray structure of the hypothetical protein Q8PZK8 from Methanosarcina mazei at the resolution 2.1A. Northeast Structural Genomics Consortium target MaR9. To be Published 0 0 0 0 1XEZ 15978620 Crystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound 2004-09-13 2005-06-14 Olson, R.,Gouaux, E. Crystal Structure of the Vibrio cholerae Cytolysin (VCC) Pro-toxin and its Assembly into a Heptameric Transmembrane Pore J.Mol.Biol. 2005 350 997 1016 1XEZ 15978620 Crystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound 2004-09-13 2005-06-14 Olson, R.,Gouaux, E. Crystal Structure of the Vibrio cholerae Cytolysin (VCC) Pro-toxin and its Assembly into a Heptameric Transmembrane Pore J.Mol.Biol. 2005 350 997 1016 1ZWK 16322580 Structure of WrbA from Pseudomonas aeruginosa 2005-06-03 2005-06-14 Gorman, J.,Shapiro, L. Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Protein Sci. 2005 14 3004 3012 1YDN 16330546 Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35. 2004-12-24 2005-07-05 Forouhar, F.,Hussain, M.,Farid, R.,Benach, J.,Abashidze, M.,Edstrom, W.C.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Fu, Z.,Kim, J.J.,Miziorko, H.M.,Montelione, G.T.,Hunt, J.F. Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. J.Biol.Chem. 2006 281 7533 7545 1YDO 16330546 Crystal Structure of the Bacillis subtilis HMG-CoA Lyase, Northeast Structural Genomics Target SR181. 2004-12-24 2005-07-05 Forouhar, F.,Hussain, M.,Farid, R.,Benach, J.,Abashidze, M.,Edstrom, W.C.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Fu, Z.,Kim, J.J.,Miziorko, H.M.,Montelione, G.T.,Hunt, J.F. Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. J.Biol.Chem. 2006 281 7533 7545 1ZXO X-ray Crystal Structure of Protein Q8A1P1 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR25. 2005-06-08 2005-07-05 Kuzin, A.P.,Yong, W.,Forouhar, F.,Vorobiev, S.,Xiao, R.,Ma, C.,Acton, T.,Montelione, G.T.,Hunt, J.,Tong, L. X-Ray structure of the hypothetical protein Q8A1P1 at the resolution 3.2A. Northeast Structural Genomics Consortium target BtR25. To be Published 0 0 0 0 1Y1M 15996549 Crystal structure of the NR1 ligand binding core in complex with cycloleucine 2004-11-18 2005-07-12 Inanobe, A.,Furukawa, H.,Gouaux, E. Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron 2005 47 71 84 1Y1Z 15996549 Crystal structure of the NR1 ligand binding core in complex with ACBC 2004-11-19 2005-07-12 Inanobe, A.,Furukawa, H.,Gouaux, E. Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron 2005 47 71 84 1Y20 15996549 Crystal structure of the NR1 ligand-binding core in complex with ACPC 2004-11-19 2005-07-12 Inanobe, A.,Furukawa, H.,Gouaux, E. Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron 2005 47 71 84 2BW7 16002394 A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen 2005-07-12 2005-07-20 Steegborn, C.,Litvin, T.N.,Hess, K.C.,Capper, A.B.,Taussig, R.,Buck, J.,Levin, L.R.,Wu, H. A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of its Complex with Catechol Estrogen J.Biol.Chem. 2005 280 31754 0 2A8E Three-dimensional structure of Bacillus subtilis Q45498 putative protein at resolution 2.5A. Northeast Structural Genomics Consortium target SR204. 2005-07-07 2005-07-26 Kuzin, A.P.,Su, M.,Yong, W.,Vorobiev, S.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.-C.,Cunningham, K.E.,Montelione, G.T.,Hunt, J.F.,Tong, L. Three-dimensional structure of Bacillus subtilis Q45498 putative protein at resolution 2.5A. Northeast Structural Genomics Consortium target SR204. To be Published 0 0 0 0 2ACA X-ray structure of a putative adenylate cyclase Q87NV8 from Vibrio parahaemolyticus at the 2.25 A resolution. Northeast Structural Genomics Target VpR19. 2005-07-18 2005-08-02 0 0 0 0 2AEG X-Ray Crystal Structure of Protein Atu5096 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR63. 2005-07-22 2005-08-02 Forouhar, F.,Abashidze, M.,Kuzin, A.P.,Vorobiev, S.M.,Shastry, R.,Cooper, B.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein Atu5096 from Agrobacterium tumefaciens. To be Published 0 0 0 0 2AFC X-Ray Crystal Structure of Protein Q8A8B0 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR9. 2005-07-25 2005-08-02 Kuzin, A.P.,Abashidze, M.,Vorobiev, S.M.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.-C.,Cunninggham, K.E.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray structure of Q8A8B0 hypothetical protein from Bacteroides thetaiotaomicron To be Published 0 0 0 0 2AF7 Crystal structure of the gamma-carboxymuconolactone decarboxylase from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Consortium target TT747. 2005-07-25 2005-08-09 Vorobiev, S.M.,Kuzin, A.,Skarina, T.,Savchenko, A.,Semesi, A.,Arrowsmith, C.,Edwards, A.,Montelione, G.T.,Tong, L. Crystal structure of the gamma-carboxymuconolactone decarboxylase from Methanobacterium thermoautotrophicum. To be Published 0 0 0 0 2AJA X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila. Northeast Structural Genomics Consortium target LgR21. 2005-08-01 2005-08-16 Kuzin, A.P.,Chen, Y.,Acton, T.,Xiao, R.,Conover, K.,Ma, C.,Kellie, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila. To be Published 0 0 0 0 1S8D 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A 2004-02-02 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T1W 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3F6I8V 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T1X 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-4L 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T1Y 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T1Z 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-6A 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T20 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-6I 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T21 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, monoclinic crystal 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 1T22 16702212 Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, orthorhombic crystal 2004-04-19 2005-09-06 Martinez-Hackert, E.,Anikeeva, N.,Kalams, S.A.,Walker, B.D.,Hendrickson, W.A.,Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem. 2006 281 20205 20212 2AWD Crystal structure of LacC from Enterococcus faecalis 2005-08-31 2005-09-13 Gorman, J.,Shapiro, L. Crystal structure of LacC from Enterococcus faecalis To be Published 0 0 0 0 2AXO X-Ray Crystal Structure of Protein AGR_C_4864 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR35. 2005-09-05 2005-09-13 Forouhar, F.,Abashidze, M.,Benach, J.,Xiao, R.,Janjua, H.,Conover, K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein AGR_C_4864 from Agrobacterium tumefaciens, NESG target AtR35 To be Published 0 0 0 0 2AXP X-Ray Crystal Structure of Protein BSU20280 from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR256. 2005-09-05 2005-09-13 Forouhar, F.,Abashidze, M.,Friedman, D.,Vorobiev, S.M.,Kuzin, A.P.,Ciao, M.,Conover, K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein BSU20280 from Bacillus subtilis, NESG target SR256 To be Published 0 0 0 0 1XEQ 17475623 Crystal tructure of RNA binding domain of influenza B virus non-structural protein 2004-09-11 2005-09-20 Yin, C.,Khan, J.A.,Swapna, G.V.,Ertekin, A.,Krug, R.M.,Tong, L.,Montelione, G.T. Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses. J.Biol.Chem. 2007 282 20584 20592 1ZES 16154092 BeF3- activated PhoB receiver domain 2005-04-19 2005-09-20 Bachhawat, P.,Swapna, G.V.,Montelione, G.T.,Stock, A.M. Mechanism of Activation for Transcription Factor PhoB Suggested by Different Modes of Dimerization in the Inactive and Active States. Structure 2005 13 1353 1363 2AJ2 X-Ray Crystal Structure of Protein VC0467 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR8. 2005-08-01 2005-09-20 Kuzin, A.P.,Abashidze, M.,Vorobiev, S.M.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.-C.,Kellie, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of hypothetical protein VC0467 from Vibrio cholerae: new fold. Northeast Structural Genomics Consortium target VcR8. To be Published 0 0 0 0 2AHX 16203964 Crystal structure of ErbB4/HER4 extracellular domain 2005-07-28 2005-09-27 Bouyain, S.,Longo, P.A.,Li, S.,Ferguson, K.M.,Leahy, D.J. The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand Proc.Natl.Acad.Sci.USA 2005 102 15024 15029 2AQ4 16195463 Ternary complex of the catalytic core of REV1 with DNA and dCTP. 2005-08-17 2005-10-04 Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science 2005 309 2219 2222 2B6E X-Ray Crystal Structure of Protein HI1161 from Haemophilus influenzae. Northeast Structural Genomics Consortium Target IR63. 2005-10-01 2005-10-11 Kuzin, A.P.,Benach, J.,Chen, Y.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.-C.,Kellie, R.,Cunningham, K.E.,Montelione, G.,Hunt, J.F.,Tong, L. X-Ray structure of the different crystal form of the hypothetical UPF0152 protein HI1161: NESG target IR63 TO BE PUBLISHED 0 0 0 0 1ZZ2 16169718 Two Classes of p38alpha MAP Kinase Inhibitors Having a Common Diphenylether Core but Exhibiting Divergent Binding Modes 2005-06-13 2005-10-18 Michelotti, E.L.,Moffett, K.K.,Nguyen, D.,Kelly, M.J.,Shetty, R.,Chai, X.,Northrop, K.,Namboodiri, V.,Campbell, B.,Flynn, G.A.,Fujimoto, T.,Hollinger, F.P.,Bukhtiyarova, M.,Springman, E.B.,Karpusas, M. Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes. Bioorg.Med.Chem.Lett. 2005 15 5274 5279 2A7W Crystal Structure of Phosphoribosyl-ATP Pyrophosphatase from Chromobacterium violaceum (ATCC 12472). NESG TARGET CVR7 2005-07-06 2005-10-25 Benach, J.,Forouhar, F.,Kuzin, A.P.,Abashidze, M.,Vorobiev, S.M.,Rong, X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F. Crystal Structure of Phosphoribosyl-ATP Pyrophosphatase from Chromobacterium violaceum. NESG Target CVR7. To be Published 0 0 0 0 2A8J 16216576 Crystal Structure of human Taspase1 (acivated form) 2005-07-08 2005-10-25 Khan, J.A.,Dunn, B.M.,Tong, L. Crystal Structure of Human Taspase1, a Crucial Protease Regulating the Function of MLL. Structure 2005 13 1443 1452 2A8L 16216576 Crystal structure of Human Taspase1 (T234A mutant) 2005-07-08 2005-10-25 Khan, J.A.,Dunn, B.M.,Tong, L. Crystal Structure of Human Taspase1, a Crucial Protease Regulating the Function of MLL. Structure 2005 13 1443 1452 2A8M 16216576 Crystal Structure of Human Taspase1 (T234S mutant) 2005-07-08 2005-10-25 Khan, J.A.,Dunn, B.M.,Tong, L. Crystal Structure of Human Taspase1, a Crucial Protease Regulating the Function of MLL. Structure 2005 13 1443 1452 2AL4 16192394 CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614. 2005-08-04 2005-10-25 Jin, R.,Clark, S.,Weeks, A.M.,Dudman, J.T.,Gouaux, E.,Partin, K.M. Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci. 2005 25 9027 9036 2AL5 16192394 Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam 2005-08-04 2005-10-25 Jin, R.,Clark, S.,Weeks, A.M.,Dudman, J.T.,Gouaux, E.,Partin, K.M. Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci. 2005 25 9027 9036 2BCO X-ray structure of succinylglutamate desuccinalase from Vibrio Parahaemolyticus (RIMD 2210633) at the resolution 2.3 A, Northeast Structural Genomics Target Vpr14 2005-10-19 2005-10-25 Kuzin, A.P.,Abashidze, M.,Forouhar, F.,Benach, J.,Zhou, W.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.C.,Kellie, R.,Cunningham, K.E.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray structure of succinylglutamate desuccinalase from Vibrio Parahaemolyticus (RIMD 2210633) at the resolution 2.3 A, Northeast Structural Genomics Target Vpr14 To be Published 0 0 0 0 2A8I 16216576 Crystal Structure of human Taspase1 2005-07-08 2005-11-01 Khan, J.A.,Dunn, B.M.,Tong, L. Crystal Structure of Human Taspase1, a Crucial Protease Regulating the Function of MLL. Structure 2005 13 1443 1452 2AP6 X-Ray Crystal Structure of Protein Atu4242 from Agrobacterium tumefaciens. Northeast Strucutral Genomics Consortium Target AtR43. 2005-08-15 2005-11-01 Benach, J.,Kuzin, A.P.,Forouhar, F.,Abashidze, M.,Vorobiev, S.M.,Rong, X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F. Crystal structure of a Hypothetical protein Atu4242 from Agrobacterium tumefaciens (strain C58 / ATCC 3 NESG Target ATR43. To be Published 0 0 0 0 2AUH 16246733 Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase 2005-08-27 2005-11-01 Depetris, R.S.,Hu, J.,Gimpelevich, I.,Holt, L.J.,Daly, R.J.,Hubbard, S.R. Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell 2005 20 325 333 2BDQ Crystal Structure of the Putative Copper Homeostasis Protein CutC from Streptococcus agalactiae, Northeast Strucural Genomics Target SaR15. 2005-10-20 2005-11-01 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Ho, C.K.,Cooper, B.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative Copper Homeostasis Protein CutC from Streptococcus agalactiae, Northeast Strucural Genomics Target SaR15. To be Published 0 0 0 0 2BDT Crystal Structure of the Putative Gluconate Kinase from Bacillus halodurans, Northeast Structural Genomics Target BhR61 2005-10-20 2005-11-01 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Janjua, H.,Cooper, B.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative Gluconate Kinase from Bacillus halodurans, Northeast Structural Genomics Target BhR61 To be Published 0 0 0 0 2BDV X-Ray Crystal Structure of Phage-related Protein BB2244 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium Target BoR24. 2005-10-20 2005-11-01 Forouhar, F.,Abashidze, M.,Benach, J.,Jayaraman, S.,Janjua, H.,Cooper, B.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the phage-related conserved hypothetical protein BB2244 from Bordetella bronchiseptica, Northeast Structural Genomics Target BoR24 To be Published 0 0 0 0 2ES7 Crystal structure of Q8ZP25 from Salmonella typhimurium LT2. NESG TARGET STR70 2005-10-25 2005-11-01 Benach, J.,Su, M.,Forouhar, F.,Chen, Y.,Janjua, H.,Rong, B.X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of Q8ZP25 from Salmonella typhimurium LT2 NESG target STR70. To be Published 0 0 0 0 2ES9 Crystal structure of Q8ZRJ2 from salmonella typhimurium. NESG TARGET STR65 2005-10-25 2005-11-01 Benach, J.,AbashidzE, M.,Jayaraman, S.,Rong, X.,Acton, T.B.,Montelione, G.T.,Tong, L. Crystal structure of Q8ZRJ2 from Salmonella typhimurium NESG TARGET STR65. To be Published 0 0 0 0 1ZYJ 16169718 Human P38 MAP Kinase in Complex with Inhibitor 1a 2005-06-10 2005-11-08 Michelotti, E.L.,Moffett, K.K.,Nguyen, D.,Kelly, M.J.,Shetty, R.,Chai, X.,Northrop, K.,Namboodiri, V.,Campbell, B.,Flynn, G.A.,Fujimoto, T.,Hollinger, F.P.,Bukhtiyarova, M.,Springman, E.B.,Karpusas, M. Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes. Bioorg.Med.Chem.Lett. 2005 15 5274 5279 2EUC Crystal structure of YfmB from Bacillus subtilis. NESG TARGET SR324 2005-10-28 2005-11-08 Benach, J.,Abashidze, M.,Jayaraman, S.,Rong, X.,Acton, T.B.,Montelione, G.T.,Tong, L. Crystal structure of YfmB from bacillus subtilis NESG TARGET SR324. To be Published 0 0 0 0 2EVE 19191354 X-Ray Crystal Structure of Protein PSPTO5229 from Pseudomonas syringae. Northeast Structural Genomics Consortium Target PsR62 2005-10-31 2005-11-08 Bertonati, C.,Punta, M.,Fischer, M.,Yachdav, G.,Forouhar, F.,Zhou, W.,Kuzin, A.P.,Seetharaman, J.,Abashidze, M.,Ramelot, T.A.,Kennedy, M.A.,Cort, J.R.,Belachew, A.,Hunt, J.F.,Tong, L.,Montelione, G.T.,Rost, B. Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins 2009 75 760 773 1ZBS Crystal Structure of the Putative N-acetylglucosamine Kinase (PG1100) from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR18 2005-04-08 2005-11-15 Forouhar, F.,Abashidze, M.,Kuzin, A.,Vorobiev, S.M.,Conover, K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative N-acetylglucosamine Kinase (PG1100) from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR18 To be Published 0 0 0 0 2A5S 16281028 Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate 2005-06-30 2005-11-15 Furukawa, H.,Singh, S.K.,Mancusso, R.,Gouaux, E. Subunit arrangement and function in NMDA receptors Nature 2005 438 185 192 2A5T 16281028 Crystal Structure Of The NR1/NR2A ligand-binding cores complex 2005-06-30 2005-11-15 Furukawa, H.,Singh, S.K.,Mancusso, R.,Gouaux, E. Subunit arrangement and function in NMDA receptors Nature 2005 438 185 192 2BDR Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49 2005-10-20 2005-11-15 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Ho, C.K.,Conover, K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49 To be Published 0 0 0 0 2C2A 16319927 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein 2005-09-27 2005-11-21 Marina, A.,Waldburger, C.D.,Hendrickson, W.A. Structure of the Entire Cytoplasmic Portion of a Sensor Histidine-Kinase Protein. Embo J. 2005 24 4247 0 2A90 16271883 Crystal Structure of the tandem WWE domain of Drosophila Deltex 2005-07-10 2005-11-22 Zweifel, M.E.,Leahy, D.J.,Barrick, D. Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex. Structure 2005 13 1599 1611 2F02 Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP 2005-11-10 2005-11-22 Gorman, J.,Shapiro, L. Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP To be Published 0 0 0 0 2F20 X-ray Crystal Structure of Protein BT_1218 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR8. 2005-11-15 2005-11-22 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Forouhar, F.,Xiao, R.,Ma, L.-C.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q8A8E9_BACTIN hypothetical protein from Bacteroides thetaiotaomicron. To be Published 0 0 0 0 2BDE Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1 2005-10-20 2005-12-06 Forouhar, F.,Abashidze, M.,Ho, C.K.,Conover, K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1 To be Published 0 0 0 0 2EW0 X-ray Crystal Structure of Protein Q6FF54 from Acinetobacter sp. ADP1. Northeast Structural Genomics Consortium Target AsR1. 2005-11-01 2005-12-06 Kuzin, A.P.,Abashidze, M.,Vorobiev, S.M.,Forouhar, F.,Acton, T.,Xiao, R.,Ma, L.-C.,Cunningham, K.E.,Montelione, G.T.,Hunt, J.F. Novel x-ray structure of hypothetical protein Q6FF54 at the resolution 1.4 A. Northeast Structural Genomics target AsR1. TO BE PUBLISHED 0 0 0 0 2EWO X-ray structure of putative agmatine deiminase Q8DW17, Northeast Structural Genomics target SmR6. 2005-11-04 2005-12-06 Kuzin, A.P.,Chen, Y.,Vorobiev, S.M.,Su, M.,Forouhar, F.,Acton, T.,Xiao, R.,Conover, K.,Ma, L.-C.,Kellie, R.,Cunningham, K.E.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray structure of putative agmatine deiminase Q8DW17, Northeast Structural Genomics target SmR6. TO BE PUBLISHED 0 0 0 0 1ZGZ 16322582 Crystal Structure Of The Receiver Domain Of TMAO Respiratory System Response Regulator TorR 2005-04-22 2005-12-13 Toro-Roman, A.,Wu, T.,Stock, A.M. A common dimerization interface in bacterial response regulators KdpE and TorR. Protein Sci. 2005 14 3077 3088 1ZH2 16322582 Crystal Structure Of The Calcium-Bound Receiver Domain Of Kdp Potassium Transport System Response Regulator KdpE 2005-04-22 2005-12-13 Toro-Roman, A.,Wu, T.,Stock, A.M. A common dimerization interface in bacterial response regulators KdpE and TorR. Protein Sci. 2005 14 3077 3088 1ZH4 16322582 Crystal Structure Of The Mg+2/BeF3-Bound Receiver Domain Of Kdp Potassium Transport System Response Regulator KdpE 2005-04-22 2005-12-13 Toro-Roman, A.,Wu, T.,Stock, A.M. A common dimerization interface in bacterial response regulators KdpE and TorR. Protein Sci. 2005 14 3077 3088 1YHK 16288456 Trypanosoma cruzi farnesyl diphosphate synthase 2005-01-09 2005-12-20 Gabelli, S.B.,McLellan, J.S.,Montalvetti, A.,Oldfield, E.,Docampo, R.,Amzel, L.M. Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins 2005 62 80 88 2F9C Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6 2005-12-05 2005-12-20 Benach, J.,Chen, Y.,Vorobiev, S.M.,Seetharaman, J.,Rong, X.,Montelione, G.T.,Tong, L. Crystal structure of YDCK from Salmonella cholerae NESG target SCR6. To be Published 0 0 0 0 2FFG Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360. 2005-12-19 2005-12-27 Kuzin, A.P.,Abashidze, M.,Forouhar, F.,Vorobiev, S.M.,Ho, C.K.,Janjua, H.,Cunningham, K.,Conover, K.,Ma, L.C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Novel x-ray structure of the YkuJ protein from Bacillus subtilis. Northeast Structural Genomics target SR360. To be Published 0 0 0 0 2FFI Crystal Structure of Putative 2-Pyrone-4,6-Dicarboxylic Acid Hydrolase from Pseudomonas putida, Northeast Structural Genomics Target PpR23. 2005-12-19 2005-12-27 Forouhar, F.,Su, M.,Jayaraman, S.,Conover, K.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of Putative 2-Pyrone-4,6-Dicarboxylic Acid Hydrolase from Pseudomonas putida, Northeast Structural Genomics Target PpR23. To be Published 0 0 0 0 2FFM X-Ray Crystal Structure of Protein SAV1430 from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR18. 2005-12-19 2005-12-27 Forouhar, F.,Chen, Y.,Jayaraman, S.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of the Hypothetical Protein SAV1430 from Staphylococcus aureus, Northeast Structural Genomics ZR18. To be Published 0 0 0 0 2AZE 16360038 Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer 2005-09-10 2006-01-31 Rubin, S.M.,Gall, A.L.,Zheng, N.,Pavletich, N.P. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell(Cambridge,Mass.) 2005 123 1093 1106 2B1F 16472744 Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat 2005-09-15 2006-01-31 Deng, Y.,Liu, J.,Zheng, Q.,Eliezer, D.,Kallenbach, N.R.,Lu, M. Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure 2006 14 247 255 2B22 16472744 Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat 2005-09-16 2006-01-31 Deng, Y.,Liu, J.,Zheng, Q.,Eliezer, D.,Kallenbach, N.R.,Lu, M. Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure 2006 14 247 255 2FDB 16384934 Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c 2005-12-13 2006-02-07 Olsen, S.K.,Li, J.Y.H.,Bromleigh, C.,Eliseenkova, A.V.,Ibrahimi, O.A.,Lao, Z.,Zhang, F.,Linhardt, R.J.,Joyner, A.L.,Mohammadi, M. Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain Genes Dev. 2006 20 185 198 2FD8 16482161 Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T 2005-12-13 2006-02-21 Yu, B.,Edstrom, W.C.,Benach, J.,Hamuro, Y.,Weber, P.C.,Gibney, B.R.,Hunt, J.F. Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. Nature 2006 439 879 884 2FDI 16482161 Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T (air 3 hours) 2005-12-14 2006-02-21 Yu, B.,Edstrom, W.C.,Benach, J.,Hamuro, Y.,Weber, P.C.,Gibney, B.R.,Hunt, J.F. Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. Nature 2006 439 879 884 2FDK 16482161 Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T (air 9 days) 2005-12-14 2006-02-21 Yu, B.,Edstrom, W.C.,Benach, J.,Hamuro, Y.,Weber, P.C.,Gibney, B.R.,Hunt, J.F. Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. Nature 2006 439 879 884 1ZWI 16532009 Structure of mutant KcsA potassium channel 2005-06-03 2006-03-07 Cordero-Morales, J.F.,Cuello, L.G.,Zhao, Y.,Jogini, V.,Cortes, D.M.,Roux, B.,Perozo, E. Molecular determinants of gating at the potassium-channel selectivity filter. Nat.Struct.Mol.Biol. 2006 13 311 318 2FLI 16489742 The crystal structure of D-ribulose 5-phosphate 3-epimerase from Streptococus pyogenes complexed with D-xylitol 5-phosphate 2006-01-06 2006-03-07 Akana, J.,Fedorov, A.A.,Fedorov, E.,Novak, W.R.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. d-Ribulose 5-Phosphate 3-Epimerase: Functional and Structural Relationships to Members of the Ribulose-Phosphate Binding (beta/alpha)(8)-Barrel Superfamily(,). Biochemistry 2006 45 2493 2503 2GAN Crystal Structure of a Putative Acetyltransferase from Pyrococcus horikoshii, Northeast Structural Genomics Target JR32. 2006-03-09 2006-03-21 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a Putative Acetyltransferase from Pyrococcus horikoshii, Northeast Structural Genomics Target JR32. To be Published 0 0 0 0 2G9D Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20 2006-03-06 2006-04-11 Zhou, W.,Jayaraman, S.,Forouhar, F.,Conover, K.,Rong, X.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20. To be Published 0 0 0 0 2GF4 Crystal structure of Vng1086c from Halobacterium salinarium (Halobacterium halobium). Northeast Structural Genomics Target HsR14 2006-03-21 2006-04-18 Benach, J.,Zhou, W.,Jayaraman, S.,Forouhar, F.F.,Janjua, H.,Xiao, R.,Ma, L.-C.,Cunningham, K.,Wang, D.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of Vng1086c from Halobacterium salinarium (Halobacterium halobium). Northeast Structural Genomics Target HsR14 To be Published 0 0 0 0 2GLU The crystal structure of YcgJ protein from Bacillus subitilis 2006-04-05 2006-04-18 Burke, T.,Gorman, J.,Shapiro, L. The crystal structure of YcgJ protein from Bacillus subitilis To be Published 0 0 0 0 1ZVN 16564015 Crystal structure of chick MN-cadherin EC1 2005-06-02 2006-04-25 Patel, S.D.,Ciatto, C.,Chen, C.P.,Bahna, F.,Rajebhosale, M.,Arkus, N.,Schieren, I.,Jessell, T.M.,Honig, B.,Price, S.R.,Shapiro, L. Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.) 2006 124 1255 1268 2A4C 16564015 Crystal structure of mouse cadherin-11 EC1 2005-06-28 2006-04-25 Patel, S.D.,Ciatto, C.,Chen, C.P.,Bahna, F.,Rajebhosale, M.,Arkus, N.,Schieren, I.,Jessell, T.M.,Honig, B.,Price, S.R.,Shapiro, L. Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.) 2006 124 1255 1268 2A4E 16564015 Crystal structure of mouse cadherin-11 EC1-2 2005-06-28 2006-04-25 Patel, S.D.,Ciatto, C.,Chen, C.P.,Bahna, F.,Rajebhosale, M.,Arkus, N.,Schieren, I.,Jessell, T.M.,Honig, B.,Price, S.R.,Shapiro, L. Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.) 2006 124 1255 1268 2DLB X-ray Crystal Structure of Protein yopT from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR412 2006-04-18 2006-04-25 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Ho, C.-K.,Cunningham, K.,Janjua, H.,Conover, K.,Ma, L.-C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray structure of hypothetical protein from Bacillus subtilis O34498 at the resolution of 1.2A. NESG target SR412 To be published 0 0 0 0 2F3B 23844654 Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase 2005-11-20 2006-04-25 Gao, Y.,Iancu, C.V.,Mukind, S.,Choe, J.Y.,Honzatko, R.B. Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase. Biochemistry 2013 52 5206 5216 2F3D 23844654 Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase 2005-11-21 2006-04-25 Gao, Y.,Iancu, C.V.,Mukind, S.,Choe, J.Y.,Honzatko, R.B. Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase. Biochemistry 2013 52 5206 5216 2GO8 Crystal structure of YQJZ_BACSU FROM Bacillus subtilis. Northeast structural genomics TARGET SR435 2006-04-12 2006-04-25 Benach, J.,Su, M.,Jayaraman, S.,Fang, Y.,Xiao, R.,Ma, L.-C.,Cunningham, K.,Wang, D.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of YQJZ_BACSU from Bacillus subtilis. Northeast Structural Genomics TARGET SR435 To be Published 0 0 0 0 2GSL X-Ray Crystal Structure of Protein FN1578 from Fusobacterium nucleatum. Northeast Structural Genomics Consortium Target NR1. 2006-04-26 2006-05-09 Forouhar, F.,Su, M.,Jayaraman, S.,Conover, K.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein (FN1578) from Fusobacterium nucleatum, NESG Target NR1 To be Published 0 0 0 0 2GSV X-Ray Crystal Structure of Protein YvfG from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR478. 2006-04-26 2006-05-09 Forouhar, F.,Su, M.,Jayaraman, S.,Wang, D.,Fang, Y.,Cunningham, K.,Conover, K.,Ma, L.-C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Hypothetical Protein YvfG from Bacillus subtilis, Northeast Structural Genomics Target SR478 To be Published 0 0 0 0 2GSW Crystal Structure of the Putative NADPH-dependent Azobenzene FMN-Reductase YhdA from Bacillus subtilis, Northeast Structural Genomics Target SR135 2006-04-26 2006-05-09 Forouhar, F.,Hussain, M.,Jayaraman, S.,Shen, J.,Cooper, B.,Cunningham, K.,Janjua, H.,Ma, L.-C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative NADPH-dependent Azobenzene FMN-Reductase YhdA from Bacillus subtilis, Northeast Structural Genomics Target SR135 To be Published 0 0 0 0 1ZV7 16698550 A structure-based mechanism of SARS virus membrane fusion 2005-06-01 2006-05-16 Deng, Y.,Liu, J.,Zheng, Q.,Yong, W.,Lu, M. Structures and Polymorphic Interactions of Two Heptad-Repeat Regions of the SARS Virus S2 Protein. Structure 2006 14 889 899 1ZV8 16698550 A structure-based mechanism of SARS virus membrane fusion 2005-06-01 2006-05-16 Deng, Y.,Liu, J.,Zheng, Q.,Yong, W.,Lu, M. Structures and Polymorphic Interactions of Two Heptad-Repeat Regions of the SARS Virus S2 Protein. Structure 2006 14 889 899 1ZVA 16698550 A structure-based mechanism of SARS virus membrane fusion 2005-06-01 2006-05-16 Deng, Y.,Liu, J.,Zheng, Q.,Yong, W.,Lu, M. Structures and Polymorphic Interactions of Two Heptad-Repeat Regions of the SARS Virus S2 Protein. Structure 2006 14 889 899 1ZVB 16698550 A structure-based mechanism of SARS virus membrane fusion 2005-06-01 2006-05-16 Deng, Y.,Liu, J.,Zheng, Q.,Yong, W.,Lu, M. Structures and Polymorphic Interactions of Two Heptad-Repeat Regions of the SARS Virus S2 Protein. Structure 2006 14 889 899 2GTC Crystal structure of the hypthetical protein from Bacillus cereus (ATCC 14579). Northeast structural genomics Target BcR11 2006-04-27 2006-05-16 SEETHARAMAN, J.,Abashidze, M.,Forouhar, F.,Conover, K.,Cooper, B.,Ma, L.-C.,Xiao, R.,B Acton, T.,Tong, L.,Hunt, J.F. Crystal structure of the hypthetical protein from Bacillus cereus (ATCC 14579). Northeast structural genomics Target BcR11 To be Published 0 0 0 0 2FKA 16674976 Crystal structure of Mg(2+) and BeF(3)(-)-bound CheY in complex with CheZ(200-214) solved from a F432 crystal grown in CAPS (pH 10.5) 2006-01-04 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FLK 16674976 Crystal structure of CheY in complex with CheZ(200-214) solved from a F432 crystal grown in CAPS (pH 10.5) 2006-01-06 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FLW 16674976 Crystal structure of Mg2+ and BeF3- ound CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Hepes (pH 7.5) 2006-01-06 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FMF 16674976 Crystal structure of CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Hepes (pH 7.5) 2006-01-09 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FMH 16674976 Crystal structure of Mg2+ and BeF3- bound CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Tris (pH 8.4) 2006-01-09 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FMI 16674976 Crystal structure of CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Tris (pH 8.4) 2006-01-09 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol. 2006 359 624 645 2FMK 16674976 Crystal structure of Mg2+ and BeF3- bound CheY in complex with CheZ 200-214 solved from a P2(1)2(1)2 crystal grown in MES (pH 6.0) 2006-01-09 2006-05-23 Guhaniyogi, J.,Robinson, V.L.,Stock, A.M. Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation J.Mol.Biol. 2006 359 624 645 2GTA Crystal Structure of the putative pyrophosphatase YPJD from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR428. 2006-04-27 2006-05-23 Vorobiev, S.M.,Zhou, W.,Seetharaman, J.,Wang, D.,Ma, L.C.,Acton, T.,Xio, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the putative pyrophosphatase YPJD from Bacillus subtilis. To be Published 0 0 0 0 2GUJ Three dimensional structure of the protein P54332 from Bacillus Subtilis. Northeast Structural Genomics Consortium target sr353. 2006-04-30 2006-05-23 Kuzin, A.P.,Zhou, W.,Seetharaman, J.,Cunningham, K.,Janjua, H.,Konover, K.,Ma, L.C.,Xiao, R.,Acton, T.,Montelione, G.,Tong, L.,Hunt, J.F. Three dimensional structure of the protein P54332 from Bacillus Subtilis. Northeast Structural Genomics Consortium target sr353. To be Published 0 0 0 0 2GWG Crystal Structure of 4-Oxalomesaconate Hydratase, LigJ, from Rhodopseudomonas palustris, Northeast Structural Genomics Target RpR66. 2006-05-04 2006-05-23 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Cunningham, K.,Ciao, M.,Ma, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of 4-Oxalomesaconate Hydratase, LigJ, from Rhodopseudomonas palustris, Northeast Structural Genomics Target RpR66 To be Published 0 0 0 0 2GXF X-Ray Crystal Structure of Protein YybH from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR506. 2006-05-08 2006-05-23 Forouhar, F.,Abashidze, M.,Jayaraman, S.,Cunningham, K.,Fang, Y.,Ma, L.-C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of the Hypothetical Protein YybH from Bacillus subtilis, Northeast Structural Genomics Target SR506 TO BE PUBLISHED 0 0 0 0 2CMU Crystal structure of a putative peptidyl-arginine deiminase 2006-05-13 2006-05-24 R Rajashankar, K.,Kniewel, R.,Solorzano, V.,Lima, C.D. Crystal Structure of a Putative Peptidyl-Arginine Deiminase. To be Published 0 0 0 0 2F23 16628221 Crystal structure of GreA factor homolog 1 (Gfh1) protein of Thermus thermophilus 2005-11-15 2006-05-30 Laptenko, O.,Kim, S.-S.,Lee, J.,Starodubtseva, M.,Cava, F.,Berenguer, J.,Kong, X.P.,Borukhov, S. pH-dependent conformational switch activates the inhibitor of transcription elongation. Embo J. 2006 25 2131 2141 2GRP 16732283 Crystal Structure of human RanGAP1-Ubc9-Y87A 2006-04-24 2006-05-30 Yunus, A.A.,Lima, C.D. Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nat.Struct.Mol.Biol. 2006 13 491 499 1ZTY Crystal Structure of the Chitin Oligasaccharide Binding Protein 2005-05-28 2006-06-06 Xu, S.,Li, X.,Roseman, R.,Stock, A.M. Crystal structure of the liganded and unliganded periplasmic Chitin oligosaccharide binding protein. To be Published 0 0 0 0 2F9F Crystal Structure of the Putative Mannosyl Transferase (wbaZ-1)from Archaeoglobus fulgidus, Northeast Structural Genomics Target GR29A. 2005-12-05 2006-06-06 Zhou, W.,Forouhar, F.,Conover, K.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative Mannosyl Transferase (wbaZ-1)from Archaeoglobus fulgidus To be Published 0 0 0 0 2ASK 16734417 Structure of human Artemin 2005-08-23 2006-06-13 Silvian, L.,Jin, P.,Carmillo, P.,Boriack-Sjodin, P.A.,Pelletier, C.,Rushe, M.,Gong, B.J.,Sah, D.,Pepinsky, B.,Rossomando, A. Artemin crystal structure reveals insights into heparan sulfate binding. Biochemistry 2006 45 6801 6812 2BDN 16682434 Crystal structure of human MCP-1 bound to a blocking antibody, 11K2 2005-10-20 2006-06-13 Reid, C.,Rushe, M.,Jarpe, M.,van Vlijmen, H.,Dolinski, B.,Qian, F.,Cachero, T.G.,Cuervo, H.,Yanachkova, M.,Nwankwo, C.,Wang, X.,Etienne, N.,Garber, E.,Bailly, V.,de Fougerolles, A.,Boriack-Sjodin, P.A. Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody. Protein Eng.Des.Sel. 2006 19 317 324 2GVG 16783377 Crystal Structure of human NMPRTase and its complex with NMN 2006-05-02 2006-06-20 Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol. 2006 13 582 588 2GVJ 16783377 Crystal Structure of Human NMPRTase in complex with FK866 2006-05-02 2006-06-20 Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol. 2006 13 582 588 2GO3 16800620 Crystal structure of Aquifex aeolicus LpxC complexed with imidazole. 2006-04-12 2006-07-04 Gennadios, H.A.,Whittington, D.A.,Li, X.,Fierke, C.A.,Christianson, D.W. Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase Biochemistry 2006 45 7940 7948 2GPS 16793549 Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli. 2006-04-18 2006-07-04 Shen, Y.,Chou, C.Y.,Chang, G.G.,Tong, L. Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell 2006 22 807 818 2GZX Crystal Structure of the TatD deoxyribonuclease MW0446 from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR237. 2006-05-12 2006-07-11 Vorobiev, S.M.,Neely, H.,Seetharaman, J.,Wang, D.,Fang, Y.,Xiao, R.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the TatD deoxyribonuclease MW0446 from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR237. To be Published 0 0 0 0 2H28 20696400 Crystal structure of YeeU from E. coli. Northeast Structural Genomics target ER304 2006-05-18 2006-07-18 Arbing, M.A.,Handelman, S.K.,Kuzin, A.P.,Verdon, G.,Wang, C.,Su, M.,Rothenbacher, F.P.,Abashidze, M.,Liu, M.,Hurley, J.M.,Xiao, R.,Acton, T.,Inouye, M.,Montelione, G.T.,Woychik, N.A.,Hunt, J.F. Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure 2010 18 996 1010 2GUS 16828114 Conformational Transition between Four- and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction 2006-05-01 2006-07-25 Liu, J.,Zheng, Q.,Deng, Y.,Kallenbach, N.R.,Lu, M. Conformational Transition between Four and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction. J.Mol.Biol. 2006 361 168 179 2GVL 16783377 Crystal Structure of Murine NMPRTase 2006-05-02 2006-07-25 Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol. 2006 13 582 588 2H4O X-ray Crystal Structure of Protein yonK from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR415 2006-05-24 2006-07-25 Seetharaman, J.,Sue, M.,Forouhar, F.,Ken, C.,Bonnie, C.,Ma, L.,Xiao, R.,Acton, T.B.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of the hypothetical protein from bacillus subtilis (yonk). To be Published 0 0 0 0 2H4T 16781677 Crystal structure of rat carnitine palmitoyltransferase II 2006-05-25 2006-07-25 Hsiao, Y.S.,Jogl, G.,Esser, V.,Tong, L. Crystal structure of rat carnitine palmitoyltransferase II (CPT-II). Biochem.Biophys.Res.Commun. 2006 346 974 980 2H6L X-Ray Crystal Structure of the Metal-containing Protein AF0104 from Archaeoglobus fulgidus. Northeast Structural Genomics Consortium Target GR103. 2006-05-31 2006-07-25 Kuzin, A.P.,Abashidze, M.,Fang, Y.,Chen, C.,Cunningham, K.,Conover, K.,Ma, L.C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Three dimensional structure of the hypothetical protein AF0104 at the 2.0 A resolution. To be Published 0 0 0 0 2HNE Crystal structure of l-fuconate dehydratase from xanthomonas campestris pv. campestris str. ATCC 33913 2006-07-12 2006-07-25 Fedorov, A.A.,Fedorov, E.V.,Yew, W.S.,Gerlt, J.A.,Almo, S.C. Crystal structure of l-fuconate dehydratase from xanthomonas campestris pv. campestris str. ATCC 33913 To be Published 0 0 0 0 2H3P 16870616 Crystal structure of murine carnitine acetyltransferase in complex with carnitine and acetyl-CoA 2006-05-22 2006-08-01 Hsiao, Y.-S.,Jogl, G.,Tong, L. Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates J.Biol.Chem. 2006 281 28480 28487 2H3U 16870616 Crystal structure of murine carnitine acetyltransferase in complex with carnitine and CoA 2006-05-23 2006-08-01 Hsiao, Y.-S.,Jogl, G.,Tong, L. Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates J.Biol.Chem. 2006 281 28480 28487 2H3W 16870616 Crystal structure of the S554A/M564G mutant of murine carnitine acetyltransferase in complex with hexanoylcarnitine and CoA 2006-05-23 2006-08-01 Hsiao, Y.-S.,Jogl, G.,Tong, L. Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates J.Biol.Chem. 2006 281 28480 28487 2HDV 16824542 Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B 2006-06-20 2006-08-08 Hu, J.,Hubbard, S.R. Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol. 2006 361 69 79 2HDX 16824542 Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide 2006-06-21 2006-08-08 Hu, J.,Hubbard, S.R. Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol. 2006 361 69 79 2H3R Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. 2006-05-23 2006-08-15 Benach, J.,Chen, Y.,Seetharaman, J.,Janjua, H.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Ho, C.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published 0 0 0 0 2H3R Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. 2006-05-23 2006-08-15 Benach, J.,Chen, Y.,Seetharaman, J.,Janjua, H.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Ho, C.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published 0 0 0 0 2HD3 17588214 Crystal Structure of the Ethanolamine Utilization Protein EutN from Escherichia coli, NESG Target ER316 2006-06-19 2006-08-15 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM. 2007 8 37 44 2HMH 16905102 Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide. 2006-07-11 2006-08-15 Bergamin, E.,Wu, J.,Hubbard, S.R. Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3. Structure 2006 14 1285 1292 2HF1 Crystal structure of the putative Tetraacyldisaccharide-1-P 4-kinase from Chromobacterium violaceum. NESG target CvR39. 2006-06-22 2006-08-22 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Chen, C.X.,Jiang, M.,Cunningham, K.,Ma, L.C.,Xiao, R.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the putative Tetraacyldisaccharide-1-P 4-kinase from Chromobacterium violaceum. To be Published 0 0 0 0 2HRX X-Ray Crystal Structure of Protein DIP2367 from Corynebacterium diphtheriae. Northeast Structural Genomics Consortium Target CdR13. 2006-07-20 2006-08-22 Kuzin, A.P.,Su, M.,Jayaraman, S.,Ho, C.K.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Three dimensional structure of conserved hypothetical protein from Corynebacterium diphtheriae at the resolution 1.9 A. Northeast Structural Genomics Consortium target CdR13. TO BE PUBLISHED 0 0 0 0 2HB5 16912289 Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain 2006-06-13 2006-08-29 Lim, D.,Gregorio, G.G.,Bingman, C.A.,Martinez-Hackert, E.,Hendrickson, W.A.,Goff, S.P. Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain. J.Virol. 2006 80 8379 8389 2HJ0 Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 . 2006-06-29 2006-08-29 Forouhar, F.,Hussain, M.,Jayaraman, S.,Shastry, R.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 (CASP Target). To be Published 0 0 0 0 2HJ1 Crystal structure of a 3D domain-swapped dimer of protein HI0395 from Haemophilus influenzae 2006-06-29 2006-08-29 Ramagopal, U.A.,Patskovsky, Y.V.,Toro, R.,Almo, S.C. Crystal structure of a 3D domain-swapped dimer of hypothetical protein from Haemophilus influenzae (CASP Target) To be Published 0 0 0 0 2I2L X-ray Crystal Structure of Protein yopX from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR411. 2006-08-16 2006-08-29 Vorobiev, S.M.,Zhou, W.,Seetharaman, J.,Forouhar, F.,Kuzin, A.A.,Ho, C.K.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the hypothetical protein yopX from Bacillus subtilis To be Published 0 0 0 0 2I4R Crystal structure of the V-type ATP synthase subunit F from Archaeoglobus fulgidus. NESG target GR52A. 2006-08-22 2006-08-29 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Zhao, L.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the V-type ATP synthase subunit F from Archaeoglobus fulgidus To be Published 0 0 0 0 2HY3 18058037 Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate 2006-08-04 2006-09-05 Almo, S.C.,Bonanno, J.B.,Sauder, J.M.,Emtage, S.,Dilorenzo, T.P.,Malashkevich, V.,Wasserman, S.R.,Swaminathan, S.,Eswaramoorthy, S.,Agarwal, R.,Kumaran, D.,Madegowda, M.,Ragumani, S.,Patskovsky, Y.,Alvarado, J.,Ramagopal, U.A.,Faber-Barata, J.,Chance, M.R.,Sali, A.,Fiser, A.,Zhang, Z.Y.,Lawrence, D.S.,Burley, S.K. Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM. 2007 8 121 140 2I5Q 18754693 Crystal structure of Apo L-rhamnonate dehydratase from Escherichia Coli 2006-08-25 2006-09-05 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Hubbard, B.K.,Delli, J.D.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase. Biochemistry 2008 47 9944 9954 2I52 Crystal structure of protein PTO0218 from Picrophilus torridus, Pfam DUF372 2006-08-23 2006-09-12 Ramagopal, U.A.,Gilmore, J.,Toro, R.,Bain, K.T.,McKenzie, C.,Reyes, C.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Structure of hypothetical protein PTO0218 from Picrophilus torridus To be Published 0 0 0 0 2HQV 17322535 X-ray Crystal Structure of Protein AGR_C_4470 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR92. 2006-07-19 2006-09-19 Vorobiev, S.M.,Neely, H.,Seetharaman, J.,Ma, L.C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L. Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens. Protein Sci. 2007 16 535 538 2HX0 Three-dimensional structure of the hypothetical protein from Salmonella cholerae-suis (aka Salmonella enterica) at the resolution 1.55 A. Northeast Structural Genomics target ScR59. 2006-08-02 2006-09-19 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Shastry, R.,Conover, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Three-dimensional structure of the hypothetical protein from Salmonella cholerae-suis (aka Salmonella enterica) at the resolution 1.55 A. Northeast Structural Genomics target ScR59. To be Published 0 0 0 0 1ZBH 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease 2005-04-08 2006-09-26 Cheng, Y.,Patel, D.J. Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA To be Published 0 0 0 0 2ID1 X-Ray Crystal Structure of Protein CV0518 from Chromobacterium violaceum, Northeast Structural Genomics Consortium Target CvR5. 2006-09-13 2006-09-26 0 0 0 0 2IA1 Crystal structure of protein BH3703 from Bacillus halodurans, Pfam DUF600 2006-09-06 2006-10-03 Ramagopal, U.A.,Russell, M.,Toro, R.,Freeman, J.C.,Reyes, C.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Structure of hypothetical protein BH3703 from Bacillus halodurans To be Published 0 0 0 0 2IBO X-ray Crystal Structure of Protein SP2199 from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR31 2006-09-11 2006-10-03 Seetharaman, J.,Abashidze, M.,Forouhar, F.,Shastry, R.,Conover, K.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the hypothetical protein SP2199 from Streptococcus pneumoniae, Northeast structural genomics target SpR31 To be Published 0 0 0 0 2IEE Crystal Structure of YCKB_BACSU from Bacillus subtilis. Northeast Structural Genomics Consortium target SR574. 2006-09-18 2006-10-03 Kuzin, A.P.,Su, M.,Seetharaman, J.,Chen, X.C.,Jang, M.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of probable ABC transporter extracellular-binding protein yckB from Bacillus subtilis. To be Published 0 0 0 0 2IF2 Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72. 2006-09-19 2006-10-03 0 0 0 0 2IFA Crystal Structure of the PUTATIVE NITROREDUCTASE (SMU.260) IN COMPLEX WITH FMN FROM STREPTOCOCCUS MUTANS, NORTHEAST STRUCTURAL GENOMICS TARGET SMR5. 2006-09-20 2006-10-03 0 0 0 0 2IFT Crystal structure of putative methylase HI0767 from Haemophilus influenzae. NESG target IR102. 2006-09-21 2006-10-10 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Shastry, R.,Janjua, H.,Ma, L.C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the putative methylase HI0767 from Haemophilus influenzae. To be Published 0 0 0 0 2I3V 17018279 Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant 2006-08-21 2006-10-17 Armstrong, N.,Jasti, J.,Beich-Frandsen, M.,Gouaux, E. Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor. Cell(Cambridge,Mass.) 2006 127 85 97 2I3W 17018279 Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of S729C mutant 2006-08-21 2006-10-17 Armstrong, N.,Jasti, J.,Beich-Frandsen, M.,Gouaux, E. Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor. Cell(Cambridge,Mass.) 2006 127 85 97 2IM8 X-Ray Crystal Structure of Protein yppE from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR213. 2006-10-03 2006-10-17 Kuzin, A.P.,Neely, H.,Seetharaman, J.,Shastry, R.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.,Tong, L.,Hunt, J.F. X-Ray structure of hypothetical protein yPPE. Northeast Structural Genomics Consortium target SR213. To be Published 0 0 0 0 2ANR 21742260 Crystal structure (II) of Nova-1 KH1/KH2 domain tandem with 25nt RNA hairpin 2005-08-11 2006-10-24 Teplova, M.,Malinina, L.,Darnell, J.C.,Song, J.,Lu, M.,Abagyan, R.,Musunuru, K.,Teplov, A.,Burley, S.K.,Darnell, R.B.,Patel, D.J. Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure 2011 19 930 944 2I0O 18058037 Crystal structure of Anopheles gambiae Ser/Thr phosphatase complexed with Zn2+ 2006-08-10 2006-10-24 Almo, S.C.,Bonanno, J.B.,Sauder, J.M.,Emtage, S.,Dilorenzo, T.P.,Malashkevich, V.,Wasserman, S.R.,Swaminathan, S.,Eswaramoorthy, S.,Agarwal, R.,Kumaran, D.,Madegowda, M.,Ragumani, S.,Patskovsky, Y.,Alvarado, J.,Ramagopal, U.A.,Faber-Barata, J.,Chance, M.R.,Sali, A.,Fiser, A.,Zhang, Z.Y.,Lawrence, D.S.,Burley, S.K. Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM. 2007 8 121 140 2IBG 17077139 Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog 2006-09-11 2006-10-24 McLellan, J.S.,Yao, S.,Zheng, X.,Geisbrecht, B.V.,Ghirlando, R.,Beachy, P.A.,Leahy, D.J. Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc.Natl.Acad.Sci.Usa 2006 103 17208 17213 2IC2 17077139 Crystal Structure of the First FNIII Domain of Ihog 2006-09-12 2006-10-24 McLellan, J.S.,Yao, S.,Zheng, X.,Geisbrecht, B.V.,Ghirlando, R.,Beachy, P.A.,Leahy, D.J. Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc.Natl.Acad.Sci.Usa 2006 103 17208 17213 2IDB Crystal Structure of 3-octaprenyl-4-hydroxybenzoate decarboxylase (UbiD) from Escherichia coli, Northeast Structural Genomics Target ER459. 2006-09-14 2006-10-24 Zhou, W.,Forouhar, F.,Seetharaman, J.,Fang, Y.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Chen, C.X.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of 3-octaprenyl-4-hydroxybenzoate decarboxylase (UbiD) from Escherichia coli, Northeast Structural Genomics Target ER459. TO BE PUBLISHED 0 0 0 0 2IEW 17050532 Crystal structure of Inositol Phosphate Multikinase Ipk2 from S. cerevisiae 2006-09-19 2006-10-24 Holmes, W.,Jogl, G. Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity. J.Biol.Chem. 2006 281 38109 38116 2IF8 17050532 Crystal structure of Inositol Phosphate Multikinase Ipk2 in complex with ADP and Mn2+ from S. cerevisiae 2006-09-20 2006-10-24 Holmes, W.,Jogl, G. Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity. J.Biol.Chem. 2006 281 38109 38116 2IM5 Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas Gingivalis 2006-10-03 2006-10-24 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas gingivalis To be Published 0 0 0 0 2IMJ X-ray Crystal Structure of Protein PFL_3262 from Pseudomonas fluorescens. Northeast Structural Genomics Consortium Target PlR14. 2006-10-04 2006-10-24 Zhou, W.,Forouhar, F.,Seetharaman, J.,Chen, C.X.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of the hypothetical protein (DUF1348) from Pseudomonas fluorescens, Northeast Structural Genomics target PlR14. TO BE PUBLISHED 0 0 0 0 2INW 20696400 Crystal structure of Q83JN9 from Shigella flexneri at high resolution. Northeast Structural Genomics Consortium target SfR137. 2006-10-09 2006-10-24 Arbing, M.A.,Handelman, S.K.,Kuzin, A.P.,Verdon, G.,Wang, C.,Su, M.,Rothenbacher, F.P.,Abashidze, M.,Liu, M.,Hurley, J.M.,Xiao, R.,Acton, T.,Inouye, M.,Montelione, G.T.,Woychik, N.A.,Hunt, J.F. Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure 2010 18 996 1010 2IN5 Crystal Structure of the hypothetical lipoprotein YmcC from Escherichia coli (K12), Northeast Structural Genomics target ER552. 2006-10-05 2006-11-07 Zhou, W.,Forouhar, F.,Seetharaman, J.,Chen, C.X.,Cunningham, K.,Ma, L.-C.,Janjua, H.,Xiao, R.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of the hypothetical lipoprotein YmcC from Escherichia coli (K12), Northeast Structural Genomics target ER552. TO BE PUBLISHED 0 0 0 0 2NMU Crystal structure of the hypothetical protein from Salmonella typhimurium LT2. Northeast Structural Genomics Consortium target StR127. 2006-10-23 2006-11-07 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Wang, H.,Nwosu, C.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.,Tong, L.,Hunt, J.F. Crystal structure of the hypothetical protein from Salmonella typhimurium LT2. Northeast Structural Genomics Consortium target StR127. To be Published 0 0 0 0 2NQ5 Crystal structure of methyltransferase from Streptococcus mutans 2006-10-30 2006-11-14 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of methyltransferase from Streptococcus mutans To be Published 0 0 0 0 2NV4 17588214 Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27 2006-11-10 2006-11-21 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.Struct.Funct.Genom. 2007 8 37 44 2HDW Crystal structure of hypothetical protein PA2218 from Pseudomonas Aeruginosa 2006-06-21 2006-11-28 Fedorov, A.A.,Fedorov, E.V.,Ramagopal, U.,Almo, S.C. Crystal structure of hypothetical protein PA2218 from Pseudomonas Aeruginosa To be Published 0 0 0 0 2HT0 17097674 IHF bound to doubly nicked DNA 2006-07-24 2006-11-28 Swinger, K.K.,Rice, P.A. Structure-based Analysis of HU-DNA Binding. J.Mol.Biol. 2007 365 1005 1016 2IEP 17011580 Crystal structure of immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK 2006-09-19 2006-11-28 Stiegler, A.L.,Burden, S.J.,Hubbard, S.R. Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK J.Mol.Biol. 2006 364 424 433 2H2I 16768447 The Structural basis of Sirtuin Substrate Affinity 2006-05-18 2006-12-05 Cosgrove, M.S.,Bever, K.,Avalos, J.L.,Muhammad, S.,Zhang, X.,Wolberger, C. The structural basis of sirtuin substrate affinity Biochemistry 2006 45 7511 7521 2HJF 17070844 Potassium channel kcsa-fab complex with tetrabutylammonium (TBA) 2006-06-30 2006-12-05 Faraldo-Gomez, J.D.,Kutluay, E.,Jogini, V.,Zhao, Y.,Heginbotham, L.,Roux, B. Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol. 2007 365 649 662 2NYS X-ray Crystal Structure of Protein AGR_C_3712 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR88. 2006-11-21 2006-12-05 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Zhao, L.,Ma, L.C.,Cunningham, K.,Nwosu, C.,Acton, T.B.,Xiao, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the hypothetical protein AGR_C_3712 from Agrobacterium tumefaciens. To be Published 0 0 0 0 2NYV X-ray crystal structure of a phosphoglycolate phosphatase from Aquifex aeolicus 2006-11-21 2006-12-05 Ciatto, C.,Min, T.,Gorman, J.,Burley, S.K.,Shapiro, L. X-ray crystal structure of a phosphoglycolate phosphatase from Aquifex aeolicus To be Published 0 0 0 0 2NYC 17223533 Crystal structure of the Bateman2 domain of yeast Snf4 2006-11-20 2006-12-12 Rudolph, M.J.,Amodeo, G.A.,Iram, S.,Hong, S.P.,Pirino, G.,Carlson, M.,Tong, L. Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding. Structure 2007 15 65 74 2NYE 17223533 Crystal structure of the Bateman2 domain of yeast Snf4 2006-11-20 2006-12-12 Rudolph, M.J.,Amodeo, G.A.,Iram, S.,Hong, S.P.,Pirino, G.,Carlson, M.,Tong, L. Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding. Structure 2007 15 65 74 2O0P X-ray Crystal Structure of Protein CC0527 (V27M / L66M double mutant) from Caulobacter crescentus. Northeast Structural Genomics Consortium Target CcR55. 2006-11-27 2006-12-12 Seetharaman, J.,Su, M.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Hypothetical Protein from Caulobacter Crescentus. TO BE PUBLISHED 0 0 0 0 2O0Q X-ray Crystal Structure of Protein CC0527 from Caulobacter crescentus. Northeast Structural Genomics Consortium Target CcR55 2006-11-28 2006-12-12 Seetharaman, J.,Su, M.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Hypothetical Protein from Caulobacter Crescentus. TO BE PUBLISHED 0 0 0 0 2O14 X-Ray Crystal Structure of Protein YXIM_BACsu from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR595 2006-11-28 2006-12-12 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Chen, C.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the hypothetical protein YXIM_BACsu from Bacillus subtilis. To be Published 0 0 0 0 2O3I X-ray Crystal Structure of Protein CV_3147 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR68. 2006-12-01 2006-12-12 Vorobiev, S.M.,Chen, Y.,Seetharaman, J.,Cunningham, K.,Ma, L.C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the hypothetical protein Q7NTB2_CHRVO from Chromobacterium violaceum To be Published 0 0 0 0 2O4L 17360759 Crystal Structure of HIV-1 Protease (Q7K, I50V) in Complex with Tipranavir 2006-12-04 2006-12-12 Muzammil, S.,Armstrong, A.A.,Kang, L.W.,Jakalian, A.,Bonneau, P.R.,Schmelmer, V.,Amzel, L.M.,Freire, E. Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations. J.Virol. 2007 81 5144 5154 2O4S 17360759 Crystal Structure of HIV-1 Protease (Q7K) in Complex with Lopinavir 2006-12-04 2006-12-12 Muzammil, S.,Armstrong, A.A.,Kang, L.W.,Jakalian, A.,Bonneau, P.R.,Schmelmer, V.,Amzel, L.M.,Freire, E. Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations. J.Virol. 2007 81 5144 5154 2DW6 17144653 Crystal structure of the mutant K184A of D-Tartrate Dehydratase from Bradyrhizobium japonicum complexed with Mg++ and D-tartrate 2006-08-07 2006-12-19 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Almo, S.C.,Gerlt, J.A. Evolution of Enzymatic Activities in the Enolase Superfamily: d-Tartrate Dehydratase from Bradyrhizobium japonicum Biochemistry 2006 45 14598 14608 2DW7 17144653 Crystal structure of D-tartrate dehydratase from Bradyrhizobium japonicum complexed with Mg++ and meso-tartrate 2006-08-07 2006-12-19 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Almo, S.C.,Gerlt, J.A. Evolution of Enzymatic Activities in the Enolase Superfamily: d-Tartrate Dehydratase from Bradyrhizobium japonicum Biochemistry 2006 45 14598 14608 2HXT 17144652 Crystal structure of L-Fuconate Dehydratase from Xanthomonas campestris liganded with Mg++ and D-erythronohydroxamate 2006-08-03 2006-12-19 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Rakus, J.F.,Pierce, R.W.,Almo, S.C.,Gerlt, J.A. Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris. Biochemistry 2006 45 14582 14597 2HXU 17144652 Crystal structure of K220A mutant of L-Fuconate Dehydratase from Xanthomonas campestris liganded with Mg++ and L-fuconate 2006-08-03 2006-12-19 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Rakus, J.F.,Pierce, R.W.,Almo, S.C.,Gerlt, J.A. Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris. Biochemistry 2006 45 14582 14597 2NW7 17197414 Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferric heme. Northeast Structural Genomics Target XcR13 2006-11-14 2006-12-19 Forouhar, F.,Anderson, J.L.,Mowat, C.G.,Vorobiev, S.M.,Hussain, A.,Abashidze, M.,Bruckmann, C.,Thackray, S.J.,Seetharaman, J.,Tucker, T.,Xiao, R.,Ma, L.C.,Zhao, L.,Acton, T.B.,Montelione, G.T.,Chapman, S.K.,Tong, L. Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase. Proc.Natl.Acad.Sci.Usa 2007 104 473 478 2NWB 17197414 Crystal Structure of a Putative 2,3-dioxygenase (SO4414) from Shewanella oneidensis in complex with ferric heme. Northeast Structural Genomics Target SoR52. 2006-11-14 2006-12-19 Forouhar, F.,Anderson, J.L.,Mowat, C.G.,Vorobiev, S.M.,Hussain, A.,Abashidze, M.,Bruckmann, C.,Thackray, S.J.,Seetharaman, J.,Tucker, T.,Xiao, R.,Ma, L.C.,Zhao, L.,Acton, T.B.,Montelione, G.T.,Chapman, S.K.,Tong, L. Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase. Proc.Natl.Acad.Sci.Usa 2007 104 473 478 2O1M Crystal structure of the probable amino-acid ABC transporter extracellular-binding protein ytmK from Bacillus subtilis. Northeast Structural Genomics Consortium target SR572 2006-11-29 2006-12-19 Kuzin, A.P.,Su, M.,Seetharaman, J.,Chen, C.,Fang, Y.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the probable amino-acid ABC transporter extracellular-binding protein ytmK from Bacillus subtilis. Northeast Structural Genomics Consortium target SR572. To be Published 0 0 0 0 2O5A Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21 2006-12-05 2006-12-19 Benach, J.,Su, M.,Seetharaman, J.,Ho, C.H.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21 To be Published 0 0 0 0 2NXE 17215866 T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with S-Adenosyl-L-Methionine 2006-11-17 2006-12-26 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J. 2007 26 567 577 2NXJ 17215866 T.thermophilus ribosomal protein L11 methyltransferase (PrmA) in space group P 21 21 2 2006-11-17 2006-12-26 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J. 2007 26 567 577 2O1S 17135236 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Escherichia coli 2006-11-29 2006-12-26 Xiang, S.,Usunow, G.,Lange, G.,Busch, M.,Tong, L. Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis. J.Biol.Chem. 2007 282 2676 2682 2O6K Crystal structure of UPF0346 from Staphylococcus aureus. Northeast Structural Genomics target ZR218. 2006-12-07 2006-12-26 Benach, J.,Abashidze, M.,Seetharaman, J.,Wang, D.,Fang, Y.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of UPF0346 from Staphylococcus aureus. Northeast Structural Genomics target ZR218. To be Published 0 0 0 0 2NWA X-ray Crystal Structure of Protein ytmB from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR466 2006-11-14 2007-01-09 Zhou, W.,Forouhar, F.,Seetharaman, J.,Wang, D.,Cunningham, K.,Ma, L.-C.,Fang, Y.,Xiao, R.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Hypothetical protein YtmB from Bacillus subtilis subsp. (subtilis str. 168), Northeast Structural Genomics target SR466 To be Published 0 0 0 0 2IPZ 17176044 A Parallel Coiled-Coil Tetramer with Offset Helices 2006-10-12 2007-01-16 Liu, J.,Deng, Y.,Zheng, Q.,Cheng, C.S.,Kallenbach, N.R.,Lu, M. A Parallel Coiled-Coil Tetramer with Offset Helices. Biochemistry 2006 45 15224 15231 2OGB 17384230 Crystal structure of the C-terminal domain of mouse Nrdp1 2007-01-05 2007-01-16 Bouyain, S.,Leahy, D.J. Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3. Protein Sci. 2007 16 654 661 2NMM Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 2006-10-22 2007-01-23 Kuzin, A.P.,Abashidze, M.,Forouhar, F.,Seetharaman, J.,Kent, C.,Fang, Y.,Cunningham, K.,Conover, K.,Ma, L.C.,Xiao, R.,Acton, T.,Montelione, G.,Tong, L.,Hunt, J.F. Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 To be Published 0 0 0 0 2I7T 17128255 Structure of human CPSF-73 2006-08-31 2007-01-30 Mandel, C.R.,Kaneko, S.,Zhang, H.,Gebauer, D.,Vethantham, V.,Manley, J.L.,Tong, L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature 2006 444 953 956 2I7V 17128255 Structure of Human CPSF-73 2006-08-31 2007-01-30 Mandel, C.R.,Kaneko, S.,Zhang, H.,Gebauer, D.,Vethantham, V.,Manley, J.L.,Tong, L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature 2006 444 953 956 2I7X 17128255 Structure of Yeast CPSF-100 (Ydh1p) 2006-08-31 2007-01-30 Mandel, C.R.,Kaneko, S.,Zhang, H.,Gebauer, D.,Vethantham, V.,Manley, J.L.,Tong, L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature 2006 444 953 956 2NVV Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16. 2006-11-13 2007-01-30 Forouhar, F.,Neely, H.,Seetharaman, J.,Yong, W.,Ho, C.K.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16 To be Published 0 0 0 0 2O71 16434054 Crystal structure of RAIDD DD 2006-12-09 2007-01-30 Park, H.H.,Wu, H. Crystal Structure of RAIDD Death Domain Implicates Potential Mechanism of PIDDosome Assembly J.Mol.Biol. 2006 357 358 364 2O8S X-ray Crystal Structure of Protein AGR_C_984 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR120. 2006-12-12 2007-01-30 Seetharaman, J.,Forouhar, F.,Su, M.,Zhao, L.,Cunningham, K.,Ma, L.-C.,Janjua, H.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Hypothetical Protein AGR_C_984 from Agrobacterium tumefaciens, Northeast Structural Genomics Target AtR120. To be Published 0 0 0 0 2OA5 17699518 Crystal structure of ORF52 from Murid herpesvirus (MUHV-4) (Murine gammaherpesvirus 68) at 2.1 A resolution. Northeast Structural Genomics Consortium target MHR28B. 2006-12-14 2007-01-30 Benach, J.,Wang, L.,Chen, Y.,Ho, C.K.,Lee, S.,Seetharaman, J.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Deng, H.,Sun, R.,Tong, L. Structural and functional studies of the abundant tegument protein ORF52 from murine gammaherpesvirus 68. J.Biol.Chem. 2007 282 31534 31541 2OOX 17289942 Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with AMP 2007-01-26 2007-02-06 Townley, R.,Shapiro, L. Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science 2007 315 1726 1729 2OOY 17289942 Crystal structure of the adenylate sensor from AMP-activated protein kinase complexed with ATP 2007-01-26 2007-02-06 Townley, R.,Shapiro, L. Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science 2007 315 1726 1729 2NXC 17215866 Apo-form of T. thermophilus ribosomal protein L11 methyltransferase (PrmA) 2006-11-17 2007-02-13 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J. 2007 26 567 577 2OTA Crystal structure of the UPF0352 protein CPS_2611 from Colwellia psychrerythraea. NESG target CsR4. 2007-02-07 2007-02-20 Vorobiev, S.M.,Zhou, W.,Su, M.,Seetharaman, J.,Wang, H.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Liu, C.,Acton, T.B.,Xiao, R.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the UPF0352 protein CPS_2611 from Colwellia psychrerythraea. NESG target CsR4. To be Published 0 0 0 0 2OYR Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with S-Adenosyl Homocysteine, Northeast Structural Genomics Target SfR275 2007-02-22 2007-03-06 Forouhar, F.,Su, M.,Seetharaman, J.,Janjua, H.,Fang, Y.,Xiao, R.,Baran, M.C.,Liu, J.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with S-Adenosyl Homocysteine, Northeast Structural Genomics Target SfR275 To be Published 0 0 0 0 2OYS 17588214 Crystal Structure of SP1951 protein from Streptococcus pneumoniae in complex with FMN, Northeast Structural Genomics Target SpR27 2007-02-22 2007-03-06 Forouhar, F.,Kuzin, A.,Seetharaman, J.,Lee, I.,Zhou, W.,Abashidze, M.,Chen, Y.,Yong, W.,Janjua, H.,Fang, Y.,Wang, D.,Cunningham, K.,Xiao, R.,Acton, T.B.,Pichersky, E.,Klessig, D.F.,Porter, C.W.,Montelione, G.T.,Tong, L. Functional insights from structural genomics. J.Struct.Funct.Genom. 2007 8 37 44 2ICW 17220897 Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule 2006-09-13 2007-03-20 Wang, L.,Zhao, Y.,Li, Z.,Guo, Y.,Jones, L.L.,Kranz, D.M.,Mourad, W.,Li, H. Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC. Nat.Struct.Mol.Biol. 2007 14 169 171 2OEK 17352497 Crystal structure of a rubisco-like protein from Geobacillus kaustophilus liganded with Mg2+ ions 2006-12-30 2007-03-20 Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanistic Diversity in the RuBisCO Superfamily: The ""Enolase"" in the Methionine Salvage Pathway in Geobacillus kaustophilus. Biochemistry 2007 46 4077 4089 2OEL 17352497 Crystal structure of a rubisco-like protein from Geobacillus kaustophilus liganded with Mg2+ and HCO3- ions 2006-12-30 2007-03-20 Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanistic Diversity in the RuBisCO Superfamily: The ""Enolase"" in the Methionine Salvage Pathway in Geobacillus kaustophilus. Biochemistry 2007 46 4077 4089 2OEM 17352497 Crystal structure of a rubisco-like protein from Geobacillus kaustophilus liganded with Mg2+ and 2,3-diketohexane 1-phosphate 2006-12-30 2007-03-20 Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanistic Diversity in the RuBisCO Superfamily: The ""Enolase"" in the Methionine Salvage Pathway in Geobacillus kaustophilus. Biochemistry 2007 46 4077 4089 2P0G Crystal structure of Selenoprotein W-related protein from Vibrio cholerae. Northeast Structural Genomics target VcR75 2007-02-28 2007-03-20 Benach, J.,Neely, H.,Seetharaman, J.,Ho, C.K.,Janjua, H.,Cunningham, K.,Ma, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of Selenoprotein W-related protein from Vibrio cholerae. To be Published 0 0 0 0 2P0V Crystal structure of BT3781 protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Target BtR58 2007-03-01 2007-03-20 Forouhar, F.,Chen, Y.,Seetharaman, J.,Janjua, H.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of BT3781 protein from Bacteroides thetaiotaomicron. To be Published 0 0 0 0 2NSA 17372359 Structures of and interactions between domains of trigger factor from Themotoga maritim 2006-11-03 2007-03-27 Martinez-Hackert, E.,Hendrickson, W.A. Structures of and interactions between domains of trigger factor from Thermotoga maritima. Acta Crystallogr.,Sect.D 2007 63 536 547 2NSB 17372359 Structures of and interactions between domains of trigger factor from Themotoga maritima 2006-11-03 2007-03-27 Martinez-Hackert, E.,Hendrickson, W.A. Structures of and interactions between domains of trigger factor from Thermotoga maritima. Acta Crystallogr.,Sect.D 2007 63 536 547 2NSC 17372359 Structures of and interactions between domains of trigger factor from Themotoga maritima 2006-11-03 2007-03-27 Martinez-Hackert, E.,Hendrickson, W.A. Structures of and interactions between domains of trigger factor from Thermotoga maritima. Acta Crystallogr.,Sect.D 2007 63 536 547 2P0Y Crystal structure of Q88YI3_LACPL from Lactobacillus plantarum. Northeast Structural Genomics Consortium target LpR6 2007-03-01 2007-03-27 Benach, J.,Chen, Y.,Seetharaman, J.,Chi, K.H.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of Q88YI3_LACPL from Lactobacillus plantarum. To be Published 0 0 0 0 2OY0 17267492 Crystal structure of the West Nile virus methyltransferase 2007-02-21 2007-04-03 Zhou, Y.,Ray, D.,Zhao, Y.,Dong, H.,Ren, S.,Li, Z.,Guo, Y.,Bernard, K.A.,Shi, P.Y.,Li, H. Structure and Function of Flavivirus NS5 Methyltransferase. J.Virol. 2007 81 3891 3903 2P76 Crystal structure of a Glycerophosphodiester Phosphodiesterase from Staphylococcus aureus 2007-03-20 2007-04-03 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of a Glycerophosphodiester Phosphodiesterase from Staphylococcus aureus To be Published 0 0 0 0 2P7N Crystal structure of the Pathogenicity island 1 effector protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium (NESGC) target CvR69. 2007-03-20 2007-04-03 Benach, J.,Abashidze, M.,Seetharaman, J.,Zhao, L.,Janjua, H.,Cunningham, K.,Ma, L.C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of the Pathogenicity island 1 effector protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium (NESGC) target CvR69. To be Published 0 0 0 0 2PAG Crystal structure of protein PSPTO_5518 from Pseudomonas syringae pv. tomato 2007-03-27 2007-04-03 Fedorov, A.A.,Ramagopal, U.,Toro, R.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of conserved hypothetical protein from Pseudomonas syringae pv. tomato. To be Published 0 0 0 0 2OND 17386263 Crystal Structure of the HAT-C domain of murine CstF-77 2007-01-23 2007-04-10 Bai, Y.,Auperin, T.C.,Chou, C.Y.,Chang, G.G.,Manley, J.L.,Tong, L. Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell 2007 25 863 875 2OOE 17386263 Crystal structure of HAT domain of murine CstF-77 2007-01-25 2007-04-10 Bai, Y.,Auperin, T.C.,Chou, C.Y.,Chang, G.G.,Manley, J.L.,Tong, L. Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell 2007 25 863 875 2P23 17339340 Crystal structure of human FGF19 2007-03-06 2007-04-10 Goetz, R.,Beenken, A.,Ibrahimi, O.A.,Kalinina, J.,Olsen, S.K.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Zhang, F.,Linhardt, R.J.,Yu, X.,White, K.E.,Inagaki, T.,Kliewer, S.A.,Yamamoto, M.,Kurosu, H.,Ogawa, Y.,Kuro-O, M.,Lanske, B.,Razzaque, M.S.,Mohammadi, M. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol. 2007 27 3417 3428 2P39 17339340 Crystal structure of human FGF23 2007-03-08 2007-04-10 Goetz, R.,Beenken, A.,Ibrahimi, O.A.,Kalinina, J.,Olsen, S.K.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Zhang, F.,Linhardt, R.J.,Yu, X.,White, K.E.,Inagaki, T.,Kliewer, S.A.,Yamamoto, M.,Kurosu, H.,Ogawa, Y.,Kuro-O, M.,Lanske, B.,Razzaque, M.S.,Mohammadi, M. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol. 2007 27 3417 3428 2OF5 17289572 Oligomeric Death Domain complex 2007-01-02 2007-04-17 Park, H.H.,Logette, E.,Raunser, S.,Cuenin, S.,Walz, T.,Tschopp, J.,Wu, H. Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex. Cell(Cambridge,Mass.) 2007 128 533 546 2OSV 17399739 Crystal Structure of ZnuA from E. coli 2007-02-06 2007-04-17 Li, H.,Jogl, G. Crystal Structure of the Zinc-binding Transport Protein ZnuA from Escherichia coli Reveals an Unexpected Variation in Metal Coordination. J.Mol.Biol. 2007 368 1358 1366 2HNW 17192588 Crystal Structure of the F91STOP mutant of des1-6 Bovine Neurophysin-I, unliganded state 2006-07-13 2007-04-24 Li, X.,Lee, H.,Wu, J.,Breslow, E. Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: crystal structures and mutation studies of bovine neurophysin-I. Protein Sci. 2007 16 52 68 2PGX Crystal structure of UPF0341 protein yhiQ from E. coli, Northeast Structural Genomics Target ER585 2007-04-10 2007-04-24 Forouhar, F.,Su, M.,Seetharaman, J.,Janjua, H.,Fang, Y.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of UPF0341 protein yhiQ from Escherichia coli. To be Published 0 0 0 0 2PH0 Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. NESG target EwR41. 2007-04-10 2007-04-24 Vorobiev, S.M.,Neely, H.,Seetharaman, J.,Chen, C.-X.,Cunningham, K.,Ma, L.-C.,Owens, L.,Xiao, R.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. To be Published 0 0 0 0 2PH1 Crystal structure of nucleotide-binding protein AF2382 from Archaeoglobus fulgidus, Northeast Structural Genomics Target GR165 2007-04-10 2007-04-24 Forouhar, F.,Abashidze, M.,Seetharaman, J.,Janjua, H.,Fang, Y.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of nucleotide-binding protein AF2382 from Archaeoglobus fulgidus. To be Published 0 0 0 0 2PHZ Crystal structure of Iron-uptake system-binding protein FeuA from Bacillus subtilis. Northeast Structural Genomics target SR580. 2007-04-12 2007-04-24 Benach, J.,Neely, H.,Seetharaman, J.,Chen, C.X.,Cunningham, K.,Ma, L.-C.,Janjua, H.,Xiao, R.,Baran, M.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal structure of Iron-uptake system-binding protein FeuA from Bacillus subtilis. To be Published 0 0 0 0 2PIG Crystal structure of ydcK from Salmonella cholerae at 2.38 A resolution. Northeast Structural Genomics target SCR6 2007-04-13 2007-04-24 Benach, J.,Chen, Y.,Vorobiev, S.M.,Seetharaman, J.,Ho, C.K.,Janjua, H.,Conover, K.,Ma, L.-C.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of ydcK from Salmonella cholerae at 2.38 A resolution. To be Published 0 0 0 0 2PIF Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. NorthEast Structural Genomics target PsR181 2007-04-13 2007-05-01 Seetharaman, J.,Abashidze, M.,Forouhar, F.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xia, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. To be Published 0 0 0 0 2PJQ Crystal structure of Q88U62_LACPL from Lactobacillus plantarum. Northeast Structural Genomics target LpR71 2007-04-16 2007-05-01 Benach, J.,Su, M.,Seetharaman, J.,Forouhar, F.,Chen, C.X.,Cunningham, K.,Ma, L.-C.,Owens, L.,Baran, M.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of Q88U62_LACPL from Lactobacillus plantarum. To be Published 0 0 0 0 2PSB Crystal structure of YerB protein from Bacillus subtilis. NorthEast Structural Genomics target SR586 2007-05-04 2007-05-15 Seetharaman, J.,Chen, Y.,Forouhar, F.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xia, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of YerB protein from Bacillus subtilis. To be Published 0 0 0 0 2PKX 17545283 E.coli response regulator PhoP receiver domain 2007-04-18 2007-05-22 Bachhawat, P.,Stock, A.M. Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog Beryllofluoride. J.Bacteriol. 2007 189 5987 5995 2PL1 17545283 Berrylium Fluoride activated receiver domain of E.coli PhoP 2007-04-18 2007-05-22 Bachhawat, P.,Stock, A.M. Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog Beryllofluoride. J.Bacteriol. 2007 189 5987 5995 2PS2 Crystal structure of putative mandelate racemase/muconate lactonizing enzyme from Aspergillus oryzae 2007-05-04 2007-05-22 Fedorov, A.A.,Toro, R.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of putative mandelate racemase/muconate lactonizing enzyme from Aspergillus oryzae. To be Published 0 0 0 0 2ELA 17502098 Crystal Structure of the PTB domain of human APPL1 2007-03-27 2007-05-29 Li, J.,Mao, X.,Dong, L.Q.,Liu, F.,Tong, L. Crystal Structures of the BAR-PH and PTB Domains of Human APPL1 Structure 2007 15 525 533 2ELB 17502098 Crystal Structure of the BAR-PH domain of human APPL1 2007-03-27 2007-05-29 Li, J.,Mao, X.,Dong, L.Q.,Liu, F.,Tong, L. Crystal Structures of the BAR-PH and PTB Domains of Human APPL1 Structure 2007 15 525 533 2P2M 17497934 Acetyl-CoA Synthetase, R194A mutation 2007-03-07 2007-05-29 Reger, A.S.,Carney, J.M.,Gulick, A.M. Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase. Biochemistry 2007 46 6536 6546 2Q00 Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus. NESG target SsR10. 2007-05-18 2007-05-29 Vorobiev, S.M.,Chen, Y.,Seetharaman, J.,Wang, D.,Owens, L.,Ma, L.-C.,Cunningham, K.,Fang, Y.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus. To be Published 0 0 0 0 2P6Y X-ray structure of the protein Q9KM02_VIBCH from Vibrio cholerae at the resolution 1.63 A. Northeast Structural Genomics Consortium target VcR80. 2007-03-19 2007-06-05 Kuzin, A.P.,Abashidze, M.,Jayaraman, S.,Chen, C.X.,Wang, C.,Fang, Y.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J. X-ray structure of the protein Q9KM02_VIBCH from Vibrio cholerae at the resolution 1.63 A. To be Published 0 0 0 0 2PG1 17551010 Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex 2007-04-06 2007-06-05 Williams, J.C.,Roulhac, P.L.,Roy, A.G.,Vallee, R.B.,Fitzgerald, M.C.,Hendrickson, W.A. Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex Proc.Natl.Acad.Sci.Usa 2007 104 10028 10033 2Q3I 10520998 Crystal structure of the D10-P3/IQN17 complex: a D-peptide inhibitor of HIV-1 entry bound to the GP41 coiled-coil pocket 2007-05-30 2007-06-12 Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket Cell(Cambridge,Mass.) 1999 99 103 105 2Q5U 10520998 Crystal structure of IQN17 2007-06-01 2007-06-12 Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket Cell(Cambridge,Mass.) 1999 99 103 105 2PTM 17562314 Structure and rearrangements in the carboxy-terminal region of SpIH channels 2007-05-08 2007-06-19 Flynn, G.E.,Black, K.D.,Islas, L.D.,Sankaran, B.,Zagotta, W.N. Structure and rearrangements in the carboxy-terminal region of SpIH channels. Structure 2007 15 671 682 2Q08 Crystal structure of the protein BH0493 from Bacillus halodurans C-125 complexed with ZN 2007-05-21 2007-06-19 Fedorov, A.A.,Fedorov, E.V.,Patskovsky, Y.,Sauder, J.M.,Burley, S.K.,Raushel, F.M.,Almo, S.C. Crystal structure of Glucoronate Isomerase from Bacillus halodurans. To be Published 0 0 0 0 2Q6E Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn 2007-06-05 2007-06-19 Fedorov, A.A.,Fedorov, E.V.,Patskovsky, Y.,Toro, R.,Sauder, J.M.,Burley, S.K.,Raushel, F.M.,Almo, S.C. Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn. To be Published 0 0 0 0 2Q7C 10520998 Crystal structure of IQN17 2007-06-06 2007-06-19 Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket Cell(Cambridge,Mass.) 1999 99 103 105 2QAI Crystal structure of the V-type ATP synthase subunit F from Pyrococcus furiosus. NESG target PfR7. 2007-06-15 2007-06-26 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Ma, L.-C.,Shih, L.,Fang, Y.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the V-type ATP synthase subunit F from Pyrococcus furiosus. To be Published 0 0 0 0 2P88 17603539 Crystal structure of N-succinyl Arg/Lys racemase from Bacillus cereus ATCC 14579 2007-03-22 2007-07-03 Song, L.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Brown, S.,Imker, H.J.,Babbitt, P.C.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Prediction and assignment of function for a divergent N-succinyl amino acid racemase. Nat.Chem.Biol. 2007 3 486 491 2P8B 17603539 Crystal structure of N-succinyl Arg/Lys racemase from Bacillus cereus ATCC 14579 complexed with N-succinyl Lys. 2007-03-22 2007-07-03 Song, L.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Brown, S.,Imker, H.J.,Babbitt, P.C.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Prediction and assignment of function for a divergent N-succinyl amino acid racemase. Nat.Chem.Biol. 2007 3 486 491 2P8C 17603539 Crystal structure of N-succinyl Arg/Lys racemase from Bacillus cereus ATCC 14579 complexed with N-succinyl Arg. 2007-03-22 2007-07-03 Song, L.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Brown, S.,Imker, H.J.,Babbitt, P.C.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Prediction and assignment of function for a divergent N-succinyl amino acid racemase. Nat.Chem.Biol. 2007 3 486 491 2POI 17560374 Crystal structure of XIAP BIR1 domain (I222 form) 2007-04-26 2007-07-03 Lu, M.,Lin, S.C.,Huang, Y.,Kang, Y.J.,Rich, R.,Lo, Y.C.,Myszka, D.,Han, J.,Wu, H. XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization. Mol.Cell 2007 26 689 702 2POM 17560374 TAB1 with manganese ion 2007-04-26 2007-07-03 Lu, M.,Lin, S.C.,Huang, Y.,Kang, Y.J.,Rich, R.,Lo, Y.C.,Myszka, D.,Han, J.,Wu, H. XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization. Mol.Cell 2007 26 689 702 2PLM 17603473 Crystal structure of the protein TM0936 from Thermotoga maritima complexed with ZN and S-inosylhomocysteine 2007-04-20 2007-07-17 Hermann, J.C.,Marti-Arbona, R.,Fedorov, A.A.,Fedorov, E.,Almo, S.C.,Shoichet, B.K.,Raushel, F.M. Structure-based activity prediction for an enzyme of unknown function Nature 2007 448 775 779 2QGG X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248. Northeast Structural Genomics Consortium target AsR73. 2007-06-28 2007-07-17 Kuzin, A.P.,Su, M.,Jayaraman, S.,Wang, D.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248. To be Published 0 0 0 0 2QGN Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41. 2007-06-29 2007-07-17 Forouhar, F.,Neely, H.,Abashidze, M.,Seetharaman, J.,Shastry, R.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans. To be Published 0 0 0 0 2QGQ 20007320 Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77 2007-06-29 2007-07-17 Arragain, S.,Garcia-Serres, R.,Blondin, G.,Douki, T.,Clemancey, M.,Latour, J.M.,Forouhar, F.,Neely, H.,Montelione, G.T.,Hunt, J.F.,Mulliez, E.,Fontecave, M.,Atta, M. Post-translational Modification of Ribosomal Proteins: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF RimO FROM THERMOTOGA MARITIMA, A RADICAL S-ADENOSYLMETHIONINE METHYLTHIOTRANSFERASE. J.Biol.Chem. 2010 285 5792 5801 2P50 17567048 Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn 2007-03-14 2007-07-24 Hall, R.S.,Brown, S.,Fedorov, A.A.,Fedorov, E.V.,Xu, C.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M. Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase. Biochemistry 2007 46 7953 7962 2P53 17567048 Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate 2007-03-14 2007-07-24 Hall, R.S.,Brown, S.,Fedorov, A.A.,Fedorov, E.V.,Xu, C.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M. Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase. Biochemistry 2007 46 7953 7962 2QGM Crystal structure of succinoglycan biosynthesis protein at the resolution 1.7 A. Northeast Structural Genomics Consortium target BcR136. 2007-06-29 2007-07-24 Kuzin, A.P.,Abashidze, M.,Jayaraman, S.,Wang, H.,Fang, Y.,Maglaqui, M.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of succinoglycan biosynthesis protein at the resolution 1.7 A. Northeast Structural Genomics Consortium target BcR136. To be Published 0 0 0 0 2QGU Three-dimensional structure of the phospholipid-binding protein from Ralstonia solanacearum Q8XV73_RALSQ in complex with a phospholipid at the resolution 1.53 A. Northeast Structural Genomics Consortium target RsR89 2007-06-29 2007-07-24 Kuzin, A.P.,Chen, Y.,Jayaraman, S.,Chen, C.X.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Three-dimensional structure of the phospholipid-binding protein from Ralstonia solanacearum Q8XV73_RALSQ in complex with a phospholipid at the resolution 1.53 A. To be Published 0 0 0 0 2QIK Crystal structure of YkqA from Bacillus subtilis. Northeast Structural Genomics Target SR631 2007-07-05 2007-07-24 Benach, J.,Chen, Y.,Forouhar, F.,Seetharaman, J.,Baran, M.C.,Cunningham, K.,Ma, L.-C.,Owens, L.,Chen, C.X.,Rong, X.,Janjua, H.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of YkqA from Bacillus subtilis. To be Published 0 0 0 0 2HVL 19053285 Crystal structure of the HePTP catalytic domain C270S mutant 2006-07-29 2007-08-07 Critton, D.A.,Tortajada, A.,Stetson, G.,Peti, W.,Page, R. Structural basis of substrate recognition by hematopoietic tyrosine phosphatase Biochemistry 2008 47 13336 13345 2OUC 17400920 Crystal structure of the MAP kinase binding domain of MKP5 2007-02-10 2007-08-07 Tao, X.,Tong, L. Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5. Protein Sci. 2007 16 880 886 2OUD 17400920 Crystal structure of the catalytic domain of human MKP5 2007-02-10 2007-08-07 Tao, X.,Tong, L. Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5. Protein Sci. 2007 16 880 886 2PP0 17649980 Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2 2007-04-27 2007-08-07 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry 2007 46 9564 9577 2PP1 17649980 Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2 liganded with Mg and L-lyxarohydroxamate 2007-04-27 2007-08-07 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry 2007 46 9564 9577 2PP3 17649980 Crystal structure of L-talarate/galactarate dehydratase mutant K197A liganded with Mg and L-glucarate 2007-04-27 2007-08-07 Yew, W.S.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry 2007 46 9564 9577 2QS9 19004028 Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978 2007-07-30 2007-08-14 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Huang, Y.J.,Chen, C.X.,Maglaqui, M.,Janjua, H.,Proudfoot, M.,Yakunin, A.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L. Crystal structure of human retinoblastoma binding protein 9. Proteins 2008 74 526 529 2O1C 17698004 Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase 2006-11-28 2007-08-28 Gabelli, S.B.,Bianchet, M.A.,Xu, W.,Dunn, C.A.,Niu, Z.D.,Amzel, L.M.,Bessman, M.J. Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis. Structure 2007 15 1014 1022 2QZU Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR123 2007-08-17 2007-09-04 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Wang, D.,Cunningham, K.,Maglaqui, M.,Owens, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. To be Published 0 0 0 0 2QT3 Crystal structure of N-Isopropylammelide isopropylaminohydrolase AtzC from Pseudomonas sp. strain ADP complexed with Zn 2007-08-01 2007-09-11 Fedorov, A.A.,Fedorov, E.V.,Seffernick, J.,Wackett, L.P.,Burley, S.K.,Almo, S.C. Crystal structure of N-Isopropylammelide isopropylaminohydrolase AtzC from Pseudomonas sp. strain ADP complexed with Zn. To be Published 0 0 0 0 2PSQ 17803937 Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain 2007-05-07 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2PVF 17803937 Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide 2007-05-09 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2PVY 17803937 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome. 2007-05-10 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2PY3 17803937 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome 2007-05-15 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2PZP 17803937 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome 2007-05-18 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2PZR 17803937 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome 2007-05-18 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2Q0B 17803937 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome 2007-05-21 2007-09-25 Chen, H.,Ma, J.,Li, W.,Eliseenkova, A.V.,Xu, C.,Neubert, T.A.,Miller, W.T.,Mohammadi, M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell 2007 27 717 730 2RA8 Crystal structure of the Q64V53_BACFR protein from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR43 2007-09-14 2007-09-25 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Wang, D.,Cunningham, K.,Maglaqui, M.,Owens, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the Q64V53_BACFR protein from Bacteroides fragilis. To be Published 0 0 0 0 2QG6 17698003 Crystal structure of human nicotinamide riboside kinase (NRK1) in complex with nicotinamide mononucleotide (NMN) 2007-06-28 2007-10-02 Khan, J.A.,Xiang, S.,Tong, L. Crystal structure of human nicotinamide riboside kinase Structure 2007 15 1005 1013 2R7F 22133431 Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63 2007-09-07 2007-10-02 Schmier, B.J.,Seetharaman, J.,Deutscher, M.P.,Hunt, J.F.,Malhotra, A. The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans. J.Mol.Biol. 2012 415 547 559 2RAD Crystal structure of the succinoglycan biosynthesis protein. Northeast structural Genomics Consortium target BcR135 2007-09-14 2007-10-02 Kuzin, A.P.,Su, M.,Seetharaman, J.,Wang, H.,Mao, L.,Cunningham, K.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the succinoglycan biosynthesis protein. To be Published 0 0 0 0 2RAG Crystal structure of aminohydrolase from Caulobacter crescentus 2007-09-14 2007-10-02 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of aminohydrolase from Caulobacter crescentus. To be Published 0 0 0 0 2RA2 X-Ray structure of the Q7CPV8 protein from Salmonella typhimurium at the resolution 1.9 A. Northeast Structural Genomics Consortium target StR88A 2007-09-14 2007-10-09 Kuzin, A.P.,Su, M.,Seetharaman, J.,Vorobiev, S.M.,Wang, H.,Mao, L.,Cunningham, K.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the Q7CPV8 protein from Salmonella typhimurium at the resolution 1.9 A. To be Published 0 0 0 0 2RD1 X-Ray structure of the protein Q7CQI7. Northeast Structural Genomics Consortium target StR87A 2007-09-20 2007-10-09 Kuzin, A.P.,Su, M.,Seetharaman, J.,Vorobiev, S.M.,Wan, D.,Fang, Y.,Owens, L.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the protein Q7CQI7. To be Published 0 0 0 0 2RAQ Crystal structure of the MTH889 protein from Methanothermobacter thermautotrophicus. Northeast Structural Genomics Consortium target TT205 2007-09-17 2007-10-16 Forouhar, F.,Su, M.,Xu, X.,Seetharaman, J.,Mao, L.,Xiao, R.,Ma, L.-C.,Conover, K.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Arrowsmith, C.H.,Hunt, J.F.,Tong, L. Crystal structure of the MTH889 protein from Methanothermobacter thermautotrophicus. To be Published 0 0 0 0 2RDN 17942405 Crystal Structure of PtlH with AKG and ent-1PL bound 2007-09-24 2007-10-16 You, Z.,Omura, S.,Ikeda, H.,Cane, D.E.,Jogl, G. Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis. J.Biol.Chem. 2007 282 36552 36560 2RDQ 17942405 Crystal Structure of PtlH with Fe/alpha ketoglutarate bound 2007-09-24 2007-10-16 You, Z.,Omura, S.,Ikeda, H.,Cane, D.E.,Jogl, G. Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis. J.Biol.Chem. 2007 282 36552 36560 2QXL 17923091 Crystal Structure Analysis of Sse1, a yeast Hsp110 2007-08-12 2007-10-23 Liu, Q.,Hendrickson, W.A. Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1. Cell(Cambridge,Mass.) 2007 131 106 120 2QXL 17923091 Crystal Structure Analysis of Sse1, a yeast Hsp110 2007-08-12 2007-10-23 Liu, Q.,Hendrickson, W.A. Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1. Cell(Cambridge,Mass.) 2007 131 106 120 2RB6 X-Ray structure of the protein Q8EI81. Northeast Structural Genomics Consortium target SoR78A 2007-09-18 2007-10-23 Kuzin, A.P.,Su, M.,Seetharaman, J.,Vorobiev, S.M.,Wang, H.,Mao, L.,Cunningham, K.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the protein Q8EI81. To be Published 0 0 0 0 2ZAY Crystal structure of response regulator from Desulfuromonas acetoxidans 2007-10-12 2007-10-23 Fedorov, A.A.,Fedorov, E.V.,Meyer, A.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of response regulator from Desulfuromonas acetoxidans. To be Published 0 0 0 0 2QJJ 17944491 Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans 2007-07-07 2007-10-30 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Vick, J.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans. Biochemistry 2007 46 12896 12908 2QJM 17944491 Crystal structure of the K271E mutant of Mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and D-mannonate 2007-07-08 2007-10-30 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Vick, J.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans. Biochemistry 2007 46 12896 12908 2QJN 17944491 Crystal structure of D-mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and 2-keto-3-deoxy-D-gluconate 2007-07-08 2007-10-30 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Vick, J.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans. Biochemistry 2007 46 12896 12908 2RDE 18034161 Crystal structure of VCA0042 complexed with c-di-GMP 2007-09-22 2007-10-30 Benach, J.,Swaminathan, S.S.,Tamayo, R.,Handelman, S.K.,Folta-Stogniew, E.,Ramos, J.E.,Forouhar, F.,Neely, H.,Seetharaman, J.,Camilli, A.,Hunt, J.F. The structural basis of cyclic diguanylate signal transduction by PilZ domains. Embo J. 2007 26 5153 5166 3B55 Crystal structure of the Q81BN2_BACCR protein from Bacillus cereus. NESG target BcR135 2007-10-25 2007-11-06 Vorobiev, S.M.,Chen, Y.,Kuzin, A.P.,Seetharaman, J.,Wang, H.,Cunningham, K.,Owens, L.,Maglaqui, M.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q81BN2_BACCR protein from Bacillus cereus. To be Published 0 0 0 0 3B57 Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. Northeast Structural Consortium target LkR65 2007-10-25 2007-11-06 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Benach, J.,Forouhar, F.,Vorobiev, S.M.,Wang, H.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. To be Published 0 0 0 0 2Q1M 18040044 Crystal Structure of human GITRL 2007-05-24 2007-11-13 Chattopadhyay, K.,Ramagopal, U.A.,Mukhopadhaya, A.,Malashkevich, V.N.,Dilorenzo, T.P.,Brenowitz, M.,Nathenson, S.G.,Almo, S.C. Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proc.Natl.Acad.Sci.USA 2007 104 19452 19457 3BB6 Crystal structure of the P64488 protein from E.coli (strain K12). Northeast Structural Genomics Consortium target ER596 2007-11-09 2007-11-20 Kuzin, A.P.,Su, M.,Seetharaman, J.,Wang, D.,Janjua, H.,Owens, L.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-Ray structure of the P64488 from E.coli (strain K12). To be Published 0 0 0 0 3BDR Crystal structure of fatty acid-binding protein-like Ycf58 from Thermosynecoccus elongatus. Northeast Structural Genomics Consortium target TeR13. 2007-11-15 2007-11-27 Kuzin, A.P.,Su, M.,Seetharaman, J.,Forouhar, F.,Wang, D.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. The crystal structure of fatty acid-binding protein-like Ycf58 from Thermosynecoccus elongatus. To be Published 0 0 0 0 3BF2 Crystal structure of the A1KSW9_NEIMF protein from Neisseria meningitidis. Northeast Structural Genomics Consortium target MR36a 2007-11-20 2007-12-04 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Cunningham, K.,Maglaqui, M.,Owens, L.,Fang, Y.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the A1KSW9_NEIMF protein from Neisseria meningitidis. To be Published 0 0 0 0 3BG2 Crystal structure of deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217 2007-11-25 2007-12-04 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Meyer, A.J.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of the deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217. To be Published 0 0 0 0 3BHP Crystal structure of UPF0291 protein ynzC from Bacillus subtilis at resolution 2.0 A. Northeast Structural Genomics Consortium target SR384 2007-11-28 2007-12-11 Kuzin, A.P.,Su, M.,Seetharaman, J.,Janjua, H.,Cunningham, K.,Maglaqui, M.,Owens, L.A.,Zhao, L.,Xiao, R.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the UPF0291 protein ynzC from Bacillus subtilis at the resolution 2.0 A. To be Published 0 0 0 0 3BEY Crystal structure of the protein O27018 from Methanobacterium thermoautotrophicum. Northeast Structural Genomics Consortium target TT217 2007-11-20 2007-12-18 Kuzin, A.P.,Gu, J.,Xu, X.,Neely, H.,Forouhar, F.,Owens, L.,Mao, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L. Crystal structure of the protein O27018 from Methanobacterium thermoautotrophicum. To be Published 0 0 0 0 3BEZ 18164727 Crystal structure of Escherichia coli Signal peptide peptidase (SppA), SeMet crystals 2007-11-20 2007-12-18 Kim, A.C.,Oliver, D.C.,Paetzel, M. Crystal structure of a bacterial signal Peptide peptidase. J.Mol.Biol. 2008 376 352 366 3BF0 18164727 Crystal structure of Escherichia coli Signal peptide peptidase (SppA), Native crystals 2007-11-20 2007-12-18 Kim, A.C.,Oliver, D.C.,Paetzel, M. Crystal structure of a bacterial signal Peptide peptidase. J.Mol.Biol. 2008 376 352 366 2QDN 18182486 Crystal Structure of mouse GITRL 2007-06-21 2008-01-01 Chattopadhyay, K.,Ramagopal, U.A.,Brenowitz, M.,Nathenson, S.G.,Almo, S.C. Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily. Proc.Natl.Acad.Sci.Usa 2008 105 635 640 3BOX 18754693 Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg 2007-12-18 2008-01-01 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Hubbard, B.K.,Delli, J.D.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase. Biochemistry 2008 47 9944 9954 2PMC 18083806 Crystal Structure of CheY-Mg(2+) in Complex with CheZ(C15) Peptide solved from a P1 Crystal 2007-04-20 2008-01-15 Guhaniyogi, J.,Wu, T.,Patel, S.S.,Stock, A.M. Interaction of CheY with the C-terminal peptide of CheZ. J.Bacteriol. 2008 190 1419 1428 3BSM Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens 2007-12-25 2008-01-15 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens. To be Published 0 0 0 0 3BEP 18191219 Structure of a sliding clamp on DNA 2007-11-19 2008-01-29 Georgescu, R.E.,Kim, S.S.,Yurieva, O.,Kuriyan, J.,Kong, X.-P.,O'Donnell, M. Structure of a sliding clamp on DNA Cell(Cambridge,Mass.) 2008 132 43 54 3BU3 18278056 Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide 2007-12-31 2008-02-19 Wu, J.,Tseng, Y.D.,Xu, C.F.,Neubert, T.A.,White, M.F.,Hubbard, S.R. Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat.Struct.Mol.Biol. 2008 15 251 258 3BU5 18278056 Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide and ATP 2007-12-31 2008-02-19 Wu, J.,Tseng, Y.D.,Xu, C.F.,Neubert, T.A.,White, M.F.,Hubbard, S.R. Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat.Struct.Mol.Biol. 2008 15 251 258 3BU6 18278056 Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB phosphopeptide 2007-12-31 2008-02-19 Wu, J.,Tseng, Y.D.,Xu, C.F.,Neubert, T.A.,White, M.F.,Hubbard, S.R. Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat.Struct.Mol.Biol. 2008 15 251 258 3C3D 18252724 Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei in complex with Fo and phosphate. Northeast Structural Genomics Consortium target MaR46 2008-01-28 2008-02-19 Forouhar, F.,Abashidze, M.,Xu, H.,Grochowski, L.L.,Seetharaman, J.,Hussain, M.,Kuzin, A.,Chen, Y.,Zhou, W.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Galinier, A.,White, R.H.,Tong, L. Molecular insights into the biosynthesis of the f420 coenzyme. J.Biol.Chem. 2008 283 11832 11840 2RDW 18215067 Crystal Structure of Human Glycolate Oxidase in Complex with Sulfate 2007-09-25 2008-02-26 Murray, M.S.,Holmes, R.P.,Lowther, W.T. Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implications for Substrate Specificity and Drug Design. Biochemistry 2008 47 2439 2449 3BG5 18297087 Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase 2007-11-26 2008-02-26 Xiang, S.,Tong, L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol. 2008 15 295 302 3BG9 18297087 Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant 2007-11-26 2008-02-26 Xiang, S.,Tong, L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol. 2008 15 295 302 3C0B Crystal structure of the conserved archaeal protein Q6M145. Northeast Structural Genomics Consortium target MrR63 2008-01-19 2008-02-26 Kuzin, A.P.,Su, M.,Seetharaman, J.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray structure of the conserved archaeal protein Q6M145. To be Published 0 0 0 0 3C96 Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240 2008-02-15 2008-02-26 Vorobiev, S.M.,Chen, Y.,Seetharaman, J.,Wang, D.,Mao, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. To be Published 0 0 0 0 3CAW 24872444 Crystal structure of o-succinylbenzoate synthase from Bdellovibrio bacteriovorus liganded with Mg 2008-02-20 2008-03-04 Odokonyero, D.,Sakai, A.,Patskovsky, Y.,Malashkevich, V.N.,Fedorov, A.A.,Bonanno, J.B.,Fedorov, E.V.,Toro, R.,Agarwal, R.,Wang, C.,Ozerova, N.D.,Yew, W.S.,Sauder, J.M.,Swaminathan, S.,Burley, S.K.,Almo, S.C.,Glasner, M.E. Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proc.Natl.Acad.Sci.USA 2014 111 8535 8540 3CB3 Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate 2008-02-21 2008-03-04 Fedorov, A.A.,Fedorov, E.V.,Yew, W.S.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate. To be Published 0 0 0 0 3CET Crystal structure of the pantheonate kinase-like protein Q6M145 at the resolution 1.8 A. Northeast Structural Genomics Consortium target MrR63 2008-02-29 2008-03-18 Kuzin, A.P.,Su, M.,Seetharaman, J.,Forouhar, F.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, J.F.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the pantheonate kinase-like protein Q6M145 at the resolution 1.8 A. Northeast Structural Genomics Consortium target MrR63. To be Published 0 0 0 0 3CFU Crystal structure of the yjhA protein from Bacillus subtilis. Northeast Structural Genomics Consortium target SR562 2008-03-04 2008-03-18 Vorobiev, S.M.,Chen, Y.,Kuzin, A.P.,Seetharaman, J.,Forouhar, F.,Zhao, L.,Mao, L.,Maglaqui, M.,Xiao, R.,Liu, J.,Swapna, G.,Huang, J.Y.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the yjhA protein from Bacillus subtilis. To be Published 0 0 0 0 3CGW 18252724 Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei. Northeast Structural Genomics Consortium target MaR46 2008-03-06 2008-03-18 Forouhar, F.,Abashidze, M.,Xu, H.,Grochowski, L.L.,Seetharaman, J.,Hussain, M.,Kuzin, A.,Chen, Y.,Zhou, W.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Galinier, A.,White, R.H.,Tong, L. Molecular insights into the biosynthesis of the f420 coenzyme. J.Biol.Chem. 2008 283 11832 11840 3BQ8 18348979 Crystal Structure of the E.coli PhoQ Sensor Domain 2007-12-19 2008-03-25 Cheung, J.,Bingman, C.A.,Reyngold, M.,Hendrickson, W.A.,Waldburger, C.D. Crystal Structure of a Functional Dimer of the PhoQ Sensor Domain. J.Biol.Chem. 2008 283 13762 13770 3CEU Crystal structure of thiamine phosphate pyrophosphorylase (BT_0647) from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR268 2008-02-29 2008-03-25 Forouhar, F.,Chen, Y.,Seetharaman, J.,Janjua, H.,Mao, L.,Xiao, R.,Foote, E.L.,Maglaqui, M.,Ciccosanti, C.,Zhao, L.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of thiamine phosphate pyrophosphorylase (BT_0647) from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR268. To be Published 0 0 0 0 3CER Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13 2008-02-29 2008-04-01 Kuzin, A.P.,Su, M.,Yang, C.,Neely, H.,Seetharaman, J.,Shastry, R.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13. To be Published 0 0 0 0 3BS1 18462677 Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with a Novel Mode of Binding 2007-12-21 2008-04-08 Sidote, D.J.,Barbieri, C.M.,Wu, T.,Stock, A.M. Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding. Structure 2008 16 727 735 3CNW Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. 2008-03-26 2008-04-08 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Wang, H.,Ciccosanti, C.,Mao, L.,Xiao, R.,Nair, R.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. To Be Published 0 0 0 0 3CPK Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis. Northeast Structural Genomics Consortium target BeR31 2008-03-31 2008-04-15 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Zhao, L.,Janjua, H.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis. To be Published 0 0 0 0 3CQ9 Crystal structure of the lp_1622 protein from Lactobacillus plantarum. Northeast Structural Genomics Consortium target LpR114 2008-04-02 2008-04-15 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Zhao, L.,Maglaqui, M.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the lp_1622 protein from Lactobacillus plantarum. To be Published 0 0 0 0 3CT2 19220063 Crystal structure of muconate cycloisomerase from Pseudomonas fluorescens 2008-04-11 2008-04-29 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes. Biochemistry 2009 48 1445 1453 2Q6Q 18850724 Crystal structure of Spc42p, a critical component of spindle pole body in budding yeast 2007-06-05 2008-05-13 Zizlsperger, N.,Malashkevich, V.N.,Pillay, S.,Keating, A.E. Analysis of coiled-coil interactions between core proteins of the spindle pole body. Biochemistry 2008 47 11858 11868 3CWQ Crystal structure of chromosome partitioning protein (ParA) in complex with ADP from Synechocystis sp. Northeast Structural Genomics Consortium Target SgR89 2008-04-22 2008-05-13 Forouhar, F.,Neely, H.,Seetharaman, J.,Mao, L.,Xiao, R.,Janjua, H.,Maglaqui, M.,Foote, E.L.,Lee, D.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of chromosome partitioning protein (ParA) in complex with ADP from Synechocystis sp. To be Published 0 0 0 0 3CJQ 18611379 Ribosomal protein L11 methyltransferase (PrmA) in complex with dimethylated ribosomal protein L11 in space group P212121 2008-03-13 2008-05-20 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase. Structure 2008 16 1059 1066 3CJR 18611379 Ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11 (K39A) and inhibitor Sinefungin. 2008-03-13 2008-05-20 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase. Structure 2008 16 1059 1066 3CJS 18611379 Minimal Recognition Complex between PrmA and Ribosomal Protein L11 2008-03-13 2008-05-20 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase. Structure 2008 16 1059 1066 3D0W Crystal structure of YflH protein from Bacillus subtilis. Northeast Structural Genomics Consortium target SR326 2008-05-02 2008-05-20 Seetharaman, J.,Kuzin, A.P.,Neely, H.,Forouhar, F.,Min, S.,Zhao, L.,Fang, Y.,Owens, L.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of YflH protein from Bacillus subtilis. To be Published 0 0 0 0 3COJ 18452305 Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from Human Acetyl-CoA Carboxylase 1 2008-03-28 2008-05-27 Shen, Y.,Tong, L. Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1 Biochemistry 2008 47 5767 5773 3D46 Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and L-tartrate 2008-05-14 2008-06-03 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and L-tartrate. To be Published 0 0 0 0 3D47 Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate 2008-05-14 2008-06-03 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate. To be Published 0 0 0 0 2R2V 18052214 Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil 2007-08-27 2008-06-17 Liu, J.,Zheng, Q.,Deng, Y.,Li, Q.,Kallenbach, N.R.,Lu, M. Conformational specificity of the lac repressor coiled-coil tetramerization domain. Biochemistry 2007 46 14951 14959 3DDM CRYSTAL STRUCTURE OF MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM Bordetella bronchiseptica RB50 2008-06-05 2008-06-24 Fedorov, A.A.,Fedorov, E.A.,Toro, R.,Sauder, M.J.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM Bordetella bronchiseptica RB50 To be Published 0 0 0 0 3CYI 18579529 Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ATP:Mg2+ 2008-04-25 2008-07-01 Jonsson, T.J.,Murray, M.S.,Johnson, L.C.,Lowther, W.T. Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Sulfiredoxin Proceeds Directly through a Sulfinic Phosphoryl Ester Intermediate. J.Biol.Chem. 2008 283 23846 23851 3DBA 18614542 Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C 2008-05-30 2008-07-01 Martinez, S.E.,Heikaus, C.C.,Klevit, R.E.,Beavo, J.A. The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change. J.Biol.Chem. 2008 283 25913 25919 3DKB 18164316 Crystal Structure of A20, 2.5 angstrom 2008-06-24 2008-07-08 Lin, S.-C.,Chung, J.Y.,Lamothe, B.,Rajashankar, K.,Lu, M.,Lo, Y.-C.,Lam, A.Y.,Darnay, B.G.,Wu, H. Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20 J.Mol.Biol. 2008 376 526 540 3D5N Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125. 2008-05-16 2008-07-15 Vorobiev, S.M.,Chen, Y.,Seetharaman, J.,Lee, D.,Foote, R.E.,Maglaqui, M.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125. To be Published 0 0 0 0 3CF4 18621675 Structure of the CODH component of the M. barkeri ACDS complex 2008-03-01 2008-07-22 Gong, W.,Hao, B.,Wei, Z.,Ferguson Jr., D.J.,Tallant, T.,Krzycki, J.A.,Chan, M.K. Structure of the alpha2 epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarboxylase/synthase complex Proc.Natl.Acad.Sci.USA 2008 105 9558 9563 3CF4 18621675 Structure of the CODH component of the M. barkeri ACDS complex 2008-03-01 2008-07-22 Gong, W.,Hao, B.,Wei, Z.,Ferguson Jr., D.J.,Tallant, T.,Krzycki, J.A.,Chan, M.K. Structure of the alpha2 epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarboxylase/synthase complex Proc.Natl.Acad.Sci.USA 2008 105 9558 9563 3D1E 18678908 Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide 2008-05-05 2008-07-29 Georgescu, R.E.,Yurieva, O.,Kim, S.S.,Kuriyan, J.,Kong, X.P.,O'Donnell, M. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa 2008 105 11116 11121 3D1F 18678908 Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide 2008-05-05 2008-07-29 Georgescu, R.E.,Yurieva, O.,Kim, S.S.,Kuriyan, J.,Kong, X.P.,O'Donnell, M. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa 2008 105 11116 11121 3D1G 18678908 Structure of a small molecule inhibitor bound to a DNA sliding clamp 2008-05-05 2008-07-29 Georgescu, R.E.,Yurieva, O.,Kim, S.S.,Kuriyan, J.,Kong, X.P.,O'Donnell, M. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa 2008 105 11116 11121 3D94 18566589 Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP 2008-05-26 2008-07-29 Wu, J.,Li, W.,Craddock, B.P.,Foreman, K.W.,Mulvihill, M.J.,Ji, Q.S.,Miller, W.T.,Hubbard, S.R. Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor Embo J. 2008 27 1985 1994 3DA1 X-Ray structure of the glycerol-3-phosphate dehydrogenase from Bacillus halodurans complexed with FAD. Northeast Structural Genomics Consortium target BhR167. 2008-05-28 2008-07-29 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Wang, D.,Janjua, H.,Owens, L.,Xiao, R.,Nair, R.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of the glycerol-3-phosphate dehydrogenase from Bacillus halodurans complexed with FAD. Northeast Structural Genomics Consortium target BhR167. To be Published 0 0 0 0 3DB9 Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186 2008-05-30 2008-07-29 Seetharaman, J.,Abashidze, M.,Wang, D.,Janjua, H.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186 (CASP Target) TO BE PUBLISHED 0 0 0 0 2QVF mouse E-cadherin domains 1,2 2007-08-08 2008-08-12 Carroll, K.J. E-cadherin domains 1,2 To be Published 0 0 0 0 3BY8 18701447 Crystal Structure of the E.coli DcuS Sensor Domain 2008-01-15 2008-08-12 Cheung, J.,Hendrickson, W.A. Crystal Structures of C4-Dicarboxylate Ligand Complexes with Sensor Domains of Histidine Kinases DcuS and DctB. J.Biol.Chem. 2008 283 30256 30265 3BY9 18701447 Crystal structure of the V. cholerae Histidine Kinase DctB Sensor Domain 2008-01-15 2008-08-12 Cheung, J.,Hendrickson, W.A. Crystal Structures of C4-Dicarboxylate Ligand Complexes with Sensor Domains of Histidine Kinases DcuS and DctB. J.Biol.Chem. 2008 283 30256 30265 3DHN Crystal structure of the putative epimerase Q89Z24_BACTN from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR310. 2008-06-18 2008-08-12 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Foote, L.E.,Janjua, H.,Xiao, R.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the putative epimerase Q89Z24_BACTN from Bacteroides thetaiotaomicron. To be Published 0 0 0 0 3DJB Crystal structure of a HD-superfamily hydrolase (BT9727_1981) from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR114 2008-06-23 2008-08-19 Forouhar, F.,Su, M.,Seetharaman, J.,Vorobiev, S.M.,Janjua, H.,Fang, Y.,Xiao, R.,Cunningham, K.,Maglaqui, M.,Owen, L.A.,Wang, D.,Baran, M.C.,Liu, J.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of a HD-superfamily hydrolase (BT9727_1981) from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR114 To be Published 0 0 0 0 3E48 Crystal structure of a nucleoside-diphosphate-sugar epimerase (SAV0421) from Staphylococcus aureus, Northeast Structural Genomics Consortium Target ZR319 2008-08-11 2008-08-19 0 0 0 0 3CT7 18700786 Crystal structure of D-allulose 6-phosphate 3-epimerase from Escherichia Coli K-12 2008-04-11 2008-08-26 Chan, K.K.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12. Biochemistry 2008 47 9608 9617 3DL3 Crystal structure of the tellurite resistance protein TehB. Northeast Structural Genomics Consortium target VfR98 . 2008-06-26 2008-08-26 Kuzin, A.P.,Su, M.,Seetharaman, J.,Wang, D.,Mao, L.,Maglaqui, M.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the tellurite resistance protein TehB. Northeast Structural Genomics Consortium target VfR98. To be Published 0 0 0 0 3DM3 Crystal structure of a domain of a Replication factor A protein, from Methanocaldococcus jannaschii. NorthEast Structural Genomics target MjR118E 2008-06-30 2008-08-26 Seetharaman, J.,Su, M.,Maglaqui, M.,Janjua, H.,Ciccosanti, C.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of a domain of a Replication factor A protein, from Methanocaldococcus jannaschii. NorthEast Structural Genomics target MjR118E To be Published 0 0 0 0 3DME Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141 2008-06-30 2008-08-26 Seetharaman, J.,Abashidze, M.,Wang, D.,Janjua, H.,Foote, E.L.,Xiao, R.,Liu, J.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of conserved exported protein from Bordetella pertussis. NorthEast Structural Genomics target BeR141 To be Published 0 0 0 0 3CW8 18620418 4-Chlorobenzoyl-CoA Ligase/Synthetase, bound to 4CBA-Adenylate 2008-04-21 2008-09-02 Reger, A.S.,Wu, R.,Dunaway-Mariano, D.,Gulick, A.M. Structural characterization of a 140 degrees domain movement in the two-step reaction catalyzed by 4-chlorobenzoate:CoA ligase. Biochemistry 2008 47 8016 8025 3E96 Crystal structure of dihydrodipicolinate synthase from bacillus clausii 2008-08-21 2008-09-02 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of dihydrodipicolinate synthase from bacillus clausii To be Published 0 0 0 0 3DR5 Crystal structure of the Q8NRD3_CORGL protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium target CgR117. 2008-07-10 2008-09-09 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Foote, E.L.,Mao, L.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the Q8NRD3_CORGL protein from Corynebacterium glutamicum. To be Published 0 0 0 0 3DSM Crystal structure of the surface layer protein BACUNI_02894 from Bacteroides uniformis, Northeast Structural Genomics Consortium Target BtR193D. 2008-07-13 2008-09-09 Forouhar, F.,Lew, S.,Seetharaman, J.,Mao, L.,Janjua, H.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Maglaqui, M.,K Everett, J.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the surface layer protein BACUNI_02894 from Bacteroides uniformis, Northeast Structural Genomics Consortium Target BtR193D. To be Published 0 0 0 0 3DTO Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130. 2008-07-15 2008-09-09 Forouhar, F.,Su, M.,Seetharaman, J.,Janjua, H.,Fang, Y.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Owen, L.A.,Wang, D.,Tong, S.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130. To be Published 0 0 0 0 3CVH 18703505 How TCR-like antibody recognizes MHC-bound peptide 2008-04-18 2008-09-23 Mareeva, T.,Martinez-Hackert, E.,Sykulev, Y. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide J.Biol.Chem. 2008 283 29053 29059 3CXO 18754693 Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and 3-deoxy-L-rhamnonate 2008-04-24 2008-09-23 Rakus, J.F.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Hubbard, B.K.,Delli, J.D.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase. Biochemistry 2008 47 9944 9954 3EB3 18806782 Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone 2008-08-26 2008-09-23 Pan, Y.,Weng, J.,Kabaleeswaran, V.,Li, H.,Cao, Y.,Bhosle, R.C.,Zhou, M. Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol. 2008 4 708 714 3EGV 18611379 Ribosomal protein L11 methyltransferase (PrmA) in complex with trimethylated ribosomal protein L11 2008-09-11 2008-09-23 Demirci, H.,Gregory, S.T.,Dahlberg, A.E.,Jogl, G. Multiple-site trimethylation of ribosomal protein L11 by the PrmA methyltransferase. Structure 2008 16 1059 1066 3E0E Crystal structure of a domain of replication protein A from Methanococcus maripaludis. NorthEast Structural Genomics targe MrR110B 2008-07-31 2008-09-30 Seetharaman, J.,Chen, Y.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of a domain of replication protein A from Methanococcus maripaludis. NorthEast Structural Genomics targe MrR110B To be Published 0 0 0 0 3E0H Crystal structure of an uncharacterized protein from Chlorobium tepidum. NorthEast Structural Genomics target CtR107. 2008-07-31 2008-09-30 Seetharaman, J.,Chen, Y.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of an uncharacterized protein from Chlorobium tepidum. NorthEast Structural Genomics target CtR107. To be Published 0 0 0 0 3E1E Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A 2008-08-04 2008-09-30 Seetharaman, J.,Abashidze, M.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of a Thioesterase family protein from Silicibacter pomeroyi. NorthEast Structural Genomics target SiR180A To be Published 0 0 0 0 3E23 Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299 2008-08-05 2008-09-30 Forouhar, F.,Chen, Y.,Seetharaman, J.,Mao, L.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Wang, H.,Tong, S.,K Everett, J.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299 To be Published 0 0 0 0 3E29 X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A. 2008-08-05 2008-09-30 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Wang, D.,Mao, L.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A. To be Published 0 0 0 0 3E5Z X-Ray structure of the putative gluconolactonase in protein family PF08450. Northeast Structural Genomics Consortium target DrR130. 2008-08-14 2008-09-30 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Wang, D.,Mao, L.,Maglaqui, M.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Tong, S.N.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-Ray structure of the putative gluconolactonase in protein family PF08450. Northeast Structural Genomics Consortium target DrR130. To be Published 0 0 0 0 3EKG CRYSTAL STRUCTURE OF L-RHAMNONATE DEHYDRATASE FROM AZOTOBACTER VINELANDII complexed with Mg and L-TARTRATE 2008-09-19 2008-09-30 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF L-RHAMNONATE DEHYDRATASE FROM AZOTOBACTER VINELANDII complexed with Mg and L-TARTRATE To be Published 0 0 0 0 3CRP 18804028 A heterospecific leucine zipper tetramer 2008-04-07 2008-10-07 Deng, Y.,Liu, J.,Zheng, Q.,Li, Q.,Kallenbach, N.R.,Lu, M. A heterospecific leucine zipper tetramer. Chem.Biol. 2008 15 908 919 3ES7 19883118 Crystal structure of divergent enolase from Oceanobacillus Iheyensis complexed with Mg and L-malate. 2008-10-04 2008-10-21 Rakus, J.F.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.P.,Toro, R.,Bonanno, J.,Bain, K.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry 2009 48 11546 11558 3ES8 19883118 Crystal structure of divergent enolase from Oceanobacillus Iheyensis complexed with Mg and L-malate. 2008-10-04 2008-10-21 Rakus, J.F.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.P.,Toro, R.,Bonanno, J.,Bain, K.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry 2009 48 11546 11558 3ESI Crystal structure of an uncharacterized protein from Erwinia carotovora subsp. atroseptica. Northeast Structural Genomics target EwR179 2008-10-06 2008-10-21 Seetharaman, J.,Lew, S.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of an uncharacterized protein from Erwinia carotovora subsp. atroseptica. Northeast Structural Genomics target EwR179 To be Published 0 0 0 0 3EVX 19101823 Crystal structure of the human E2-like ubiquitin-fold modifier conjugating enzyme 1 (Ufc1). Northeast Structural Genomics Consortium target HR41 2008-10-13 2008-10-21 Liu, G.,Forouhar, F.,Eletsky, A.,Atreya, H.S.,Aramini, J.M.,Xiao, R.,Huang, Y.J.,Abashidze, M.,Seetharaman, J.,Liu, J.,Rost, B.,Acton, T.,Montelione, G.T.,Hunt, J.F.,Szyperski, T. NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway. J.STRUCT.FUNCT.GENOM. 2009 10 127 136 3ESH Crystal structure of a probable metal-dependent hydrolase from Staphylococcus aureus. Northeast Structural Genomics target ZR314 2008-10-06 2008-10-28 Seetharaman, J.,Chen, Y.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of a probable metal-dependent hydrolase from Staphylococcus aureus. Northeast Structural Genomics target ZR314 To be Published 0 0 0 0 3EXZ Crystal structure of the MaoC-like dehydratase from Rhodospirillum rubrum. Northeast Structural Genomics Consortium target RrR103a. 2008-10-17 2008-10-28 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Wang, H.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the MaoC-like dehydratase from Rhodospirillum rubrum. To be Published 0 0 0 0 3EW7 Crystal structure of the Lmo0794 protein from Listeria monocytogenes. Northeast Structural Genomics Consortium target LmR162. 2008-10-14 2008-11-11 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Wang, D.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Lmo0794 protein from Listeria monocytogenes. To be Published 0 0 0 0 3F08 Crystal structure of the putative uncharacterized protein Q6HG14 from Bacilllus thuringiensis. Northeast Structural Genomics Consortium target BuR153. 2008-10-24 2008-11-18 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Wang, H.,Mao, L.,Ciccosanti, C.,Xiao, R.,Nair, R.,Baran, M.C.,Swapna, G.V.T.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the putative uncharacterized protein Q6HG14 from Bacilllus thuringiensis. Northeast Structural Genomics Consortium target BuR153. To be Published 0 0 0 0 3F2Z Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B 2008-10-30 2008-11-18 Forouhar, F.,Lew, S.,Seetharaman, J.,Janjua, H.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Lee, D.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B To be Published 0 0 0 0 3DEQ 19000819 Crystal structure of dipeptide epimerase from Thermotoga maritima complexed with L-Ala-L-Leu dipeptide 2008-06-10 2008-11-25 Kalyanaraman, C.,Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure 2008 16 1668 1677 3DER 19000819 Crystal structure of dipeptide epimerase from Thermotoga maritima complexed with L-Ala-L-Lys dipeptide 2008-06-10 2008-11-25 Kalyanaraman, C.,Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure 2008 16 1668 1677 3DES 19000819 Crystal structure of dipeptide epimerase from Thermotoga maritima complexed with L-Ala-L-Phe dipeptide 2008-06-10 2008-11-25 Kalyanaraman, C.,Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure 2008 16 1668 1677 3DFY 19000819 Crystal structure of apo dipeptide epimerase from Thermotoga maritima 2008-06-12 2008-11-25 Kalyanaraman, C.,Imker, H.J.,Fedorov, A.A.,Fedorov, E.V.,Glasner, M.E.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure 2008 16 1668 1677 3F1X Three dimensional structure of the serine acetyltransferase from Bacteroides vulgatus, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BVR62. 2008-10-28 2008-11-25 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Sahdev, S.,Wang, D.,Mao, L.,Cunningham, K.,Maglaqui, M.,Xiao, R.,Liu, J.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Three dimensional structure of the serine acetyltransferase from Bacteroides vulgatus, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BVR62. To be Published 0 0 0 0 3F3B Structure of the phage-like element PBSX protein xkdH from Bacillus Subtilus. Northeast Structural Genomics Consortium target SR352. 2008-10-30 2008-11-25 Kuzin, A.P.,Neely, H.,Seetharaman, J.,Clayton, G.,Ho, C.K.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Structure of the phage-like element PBSX protein xkdH from Bacillus Subtilus. Northeast Structural Genomics Consortium target SR352. To be Published 0 0 0 0 3F4K Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. 2008-10-31 2008-11-25 Seetharaman, J.,Lew, S.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of a probable methyltransferase from Bacteroides thetaiotaomicron. Northeast Structural Genomics target BtR309. To be Published 0 0 0 0 3FB2 Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a. 2008-11-18 2008-11-25 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Shastry, R.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the human brain alpha spectrin repeats 15 and 16. To be Published 0 0 0 0 3FBK Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A 2008-11-19 2008-12-02 Forouhar, F.,Lew, S.,Seetharaman, J.,Mao, L.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A To be Published 0 0 0 0 3FCP Crystal structure of Muconate lactonizing enzyme from Klebsiella pneumoniae 2008-11-22 2008-12-02 Fedorov, A.A.,Fedorov, E.V.,Sauder, M.J.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of Muconate lactonizing enzyme from Klebsiella pneumoniae To be Published 0 0 0 0 3FAC Crystal structure of Rhodobacter sphaeroides protein RSP_2168. Northeast Structural Genomics target RhR83. 2008-11-16 2008-12-09 0 0 0 0 3EZH 19217390 Crystal Structure of the E. coli Histidine Kinase NarX Sensor Domain in Complex with Nitrate 2008-10-22 2008-12-23 Cheung, J.,Hendrickson, W.A. Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX. Structure 2009 17 190 201 3EZI 19217390 Crystal Structure of the E. coli Histidine Kinase NarX Sensor Domain without Ligand 2008-10-22 2008-12-23 Cheung, J.,Hendrickson, W.A. Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX. Structure 2009 17 190 201 3FGB Crystal structure of the Q89ZH8_BACTN protein from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR289b. 2008-12-05 2008-12-23 Vorobiev, S.M.,Lew, S.,Seetharaman, J.,Lee, D.,Foote, L.E.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q89ZH8_BACTN protein from Bacteroides thetaiotaomicron. To be Published 0 0 0 0 3FDF Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Orthorhombic crystal form. Northeast Structural Genomics Consortium target FR253. 2008-11-25 2009-01-06 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Forouhar, F.,Chinag, Y.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Orthorombic crystal structure of serine phosphatase of rna polymerase ii ctd from fly drosofila melanogaster. northeast structural genomics consortium target fr253. To be Published 0 0 0 0 3FMV Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. 2008-12-22 2009-01-06 Kuzin, A.P.,Chen, Y.,Seetharaman, J.,Forouhar, F.,Chinag, Y.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. To be Published 0 0 0 0 3FK4 Crystal structure of RuBisCO-like protein from Bacillus Cereus ATCC 14579 2008-12-15 2009-01-13 Fedorov, A.A.,V Fedorov, E.,Imker, H.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of RuBisCO-like protein from Bacillus Cereus ATCC 14579 To be Published 0 0 0 0 3FNI Crystal structure of a diflavin flavoprotein A3 (all3895) from Nostoc sp., Northeast Structural Genomics Consortium Target NsR431A 2008-12-24 2009-01-13 Forouhar, F.,Lew, S.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of a diflavin flavoprotein A3 (all3895) from Nostoc sp., Northeast Structural Genomics Consortium Target NsR431A To be Published 0 0 0 0 3FNJ Crystal structure of the full-length lp_1913 protein from Lactobacillus plantarum, Northeast Structural Genomics Consortium Target LpR140 2008-12-25 2009-01-20 Seetharaman, J.,Chen, Y.,Forouhar, F.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the full-length lp_1913 protein from Lactobacillus plantarum, Northeast Structural Genomics Consortium Target LpR140 To be Published 0 0 0 0 3FOJ Crystal Structure of SSP1007 From Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Target SyR101A. 2008-12-30 2009-01-20 Seetharaman, J.,Abashidze, M.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of SSP1007 From Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Target SyR101A. To be Published 0 0 0 0 3FOK Crystal Structure of Cgl0159 From Corynebacterium glutamicum (Brevibacterium flavum). Northeast Structural Genomics Target CgR115 2008-12-30 2009-01-20 Seetharaman, J.,Neely, H.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of Cgl0159 From Corynebacterium glutamicum (Brevibacterium flavum). Northeast Structural Genomics Target CgR115 To be Published 0 0 0 0 3C30 Crystal structure of the Vibrio Cholerae LuxQ periplasmic domain (SeMet) 2008-01-27 2009-02-03 Slama, B.,Hendrickson, W. Crystal structure of the Vibrio Cholerae LuxQ periplasmic domain (SeMet) To be Published 0 0 0 0 3CLY 19060208 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction 2008-03-20 2009-02-03 Chen, H.,Xu, C.F.,Ma, J.,Eliseenkova, A.V.,Li, W.,Pollock, P.M.,Pitteloud, N.,Miller, W.T.,Neubert, T.A.,Mohammadi, M. A crystallographic snapshot of tyrosine trans-phosphorylation in action Proc.Natl.Acad.Sci.USA 2008 105 19660 19665 3FQI 19194460 Crystal Structure of the Mouse Dom3Z 2009-01-07 2009-02-03 Xiang, S.,Cooper-Morgan, A.,Jiao, X.,Kiledjian, M.,Manley, J.L.,Tong, L. Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature 2009 458 784 788 3FXG Crystal structure of rhamnonate dehydratase from Gibberella zeae complexed with Mg 2009-01-20 2009-02-03 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of rhamnonate dehydratase from Gibberella zeae complexed with Mg To be Published 0 0 0 0 3FYY 19883118 Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with Mg 2009-01-23 2009-02-03 Rakus, J.F.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.P.,Toro, R.,Bonanno, J.,Bain, K.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry 2009 48 11546 11558 3CTL 18700786 Crystal structure of D-Allulose 6-Phosphate 3-Epimerase from Escherichia coli K12 complexed with D-glucitol 6-phosphate and magnesium 2008-04-14 2009-02-24 Chan, K.K.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12. Biochemistry 2008 47 9608 9617 3GA2 Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624 2009-02-16 2009-02-24 Forouhar, F.,Abashidze, M.,Hussain, M.,Seetharaman, J.,Janjua, H.,Fang, Y.,Xiao, R.,Cunningham, K.,Ma, L.-C.,Owens, L.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624 To be Published 0 0 0 0 3DG3 19220063 Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis 2008-06-12 2009-03-03 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry 2009 48 1445 1453 3DG6 19220063 Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone 2008-06-12 2009-03-03 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry 2009 48 1445 1453 3DG7 19220063 Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone 2008-06-12 2009-03-03 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry 2009 48 1445 1453 3DGB 19220063 Crystal structure of muconate lactonizing enzyme from Pseudomonas Fluorescens complexed with muconolactone 2008-06-13 2009-03-03 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry 2009 48 1445 1453 3GD6 Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate 2009-02-23 2009-03-03 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of divergent enolase from Oceanobacillus iheyensis complexed with phosphate. To be Published 0 0 0 0 3GEK Crystal structure of putative thioesterase yhdA from Lactococcus lactis. Northeast Structural Genomics Consortium Target KR113 2009-02-25 2009-03-17 Kuzin, A.P.,Su, M.,Seetharaman, R.,Lee, D.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Nair, R.,Rost, B.,Acton, T.B.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-Ray structure of putative thioesterase yhdA from Lactococcus lactis. Northeast Structural Genomics Consortium Target KR113 To be published 0 0 0 0 3GGN Crystal structure of DR_A0006 from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR147D 2009-02-28 2009-03-24 Seetharaman, J.,Neely, H.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of DR_A0006 from Deinococcus radiodurans. To be Published 0 0 0 0 3FJ4 19220063 Crystal structure of muconate lactonizing enzyme from Pseudomonas Fluorescens complexed with muconolactone 2008-12-14 2009-03-31 Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry 2009 48 1445 1453 3GGL X-Ray Structure of the C-terminal domain (277-440) of Putative chitobiase from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR324A. 2009-02-28 2009-03-31 Kuzin, A.,Neely, H.,Seetharaman, R.,Ciccosanti, C.,Foote, E.L.,Nair, R.,Rost, B.,Acton, T.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.,Northeast Structural Genomics Consortium (NESG) Northeast Structural Genomics Consortium Target BtR324A To be Published 0 0 0 0 3GOZ Crystal structure of the leucine-rich repeat-containing protein LegL7 from Legionella pneumophila. Northeast Structural Genomics Consortium target LgR148 2009-03-20 2009-03-31 Vorobiev, S.M.,Abashidze, M.,Seetharaman, J.,Belote, R.L.,Foote, E.L.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the leucine-rich repeat-containing protein LegL7 from Legionella pneumophila. Northeast Structural Genomics Consortium target LgR148. To be Published 0 0 0 0 3GQQ Crystal structure of the human retinal protein 4 (unc-119 homolog A). Northeast Structural Genomics Consortium target HR3066a 2009-03-24 2009-04-07 Vorobiev, S.M.,Chen, Y.,Seetharaman, J.,Shastry, R.,Foote, E.L.,Ciccosanti, C.,Sahdev, S.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the human retinal protein 4 (unc-119 homolog A). To be Published 0 0 0 0 3GU3 Crystal Structure of the methyltransferase BC_2162 in complex with S-Adenosyl-L-Homocysteine from Bacillus cereus, Northeast Structural Genomics Consortium Target BcR20 2009-03-28 2009-04-07 Forouhar, F.,Neely, H.,Seetharaman, J.,Ciano, C.,Ma, L.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target BcR20 To be Published 0 0 0 0 3GD5 Crystal structure of ornithine carbamoyltransferase from Gloeobacter violaceus 2009-02-23 2009-04-14 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Ramagopal, U.A.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of ornithine carbamoyltransferase from Gloeobacter violaceus To be Published 0 0 0 0 3GT0 Crystal structure of pyrroline 5-carboxylate reductase from Bacillus cereus. Northeast Structural Genomics Consortium Target BcR38B 2009-03-27 2009-04-21 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Shastry, R.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target BcR38B To be published 0 0 0 0 3GW2 Crystal structure of possible transcriptional regulatory protein (fragment 1-100) from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR242E. 2009-03-31 2009-04-21 Kuzin, A.P.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target MbR242E To be published 0 0 0 0 3GW4 Crystal structure of uncharacterized protein from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR162B. 2009-03-31 2009-04-21 Kuzin, A.P.,Abashidze, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target DrR162B To be published 0 0 0 0 3H2S Crystal Structure of the Q03B84 Protein from Lactobacillus casei. Northeast Structural Genomics Consortium Target LcR19. 2009-04-14 2009-04-28 Vorobiev, S.,Lew, S.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Acton, T.B.,Xiao, R.,Everett, J.,Nair, R.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q03B84 protein from Lactobacillus casei. To be Published 0 0 0 0 3H70 24872444 Crystal structure of o-succinylbenzoic acid synthetase from staphylococcus aureus Complexed with mg in the active site 2009-04-24 2009-05-05 Odokonyero, D.,Sakai, A.,Patskovsky, Y.,Malashkevich, V.N.,Fedorov, A.A.,Bonanno, J.B.,Fedorov, E.V.,Toro, R.,Agarwal, R.,Wang, C.,Ozerova, N.D.,Yew, W.S.,Sauder, J.M.,Swaminathan, S.,Burley, S.K.,Almo, S.C.,Glasner, M.E. Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proc.Natl.Acad.Sci.USA 2014 111 8535 8540 3G9R 19226163 Structure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation 2009-02-13 2009-05-12 Liu, J.,Deng, Y.,Dey, A.,Moore, J.,Lu, M. Structure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation. Biochemistry 2009 48 2915 2923 3GGM Crystal Structure of BT9727_2919 from Bacillus thuringiensis subsp. Northeast Structural Genomics Target BuR228B 2009-02-28 2009-05-12 Seetharaman, J.,Neely, H.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of BT9727_2919 from Bacillus thuringiensis subsp. Northeast Structural Genomics Target BuR228B To be Published 0 0 0 0 3GWB Crystal structure of peptidase M16 inactive domain from Pseudomonas fluorescens. Northeast Structural Genomics target PlR293L 2009-03-31 2009-05-12 Seetharaman, J.,Chen, Y.,Fang, F.,Xiao, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of peptidase M16 inactive domain from Pseudomonas fluorescens. Northeast Structural Genomics target PlR293L To be Published 0 0 0 0 3H6J 19284989 Crystal structure of a putative neuraminidase from Pseudomonas aeruginosa 2009-04-23 2009-05-12 Hsiao, Y.-S.,Parker, D.,Ratner, A.J.,Prince, A.,Tong, L. Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun. 2009 380 467 471 3H71 19284989 Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) 2009-04-24 2009-05-12 Hsiao, Y.-S.,Parker, D.,Ratner, A.J.,Prince, A.,Tong, L. Crystal structures of respiratory pathogen neuraminidases Biochem.Biophys.Res.Commun. 2009 380 467 471 3H7V 24872444 CRYSTAL STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE FROM THERMOSYNECHOCOCCUS ELONGATUS BP-1 complexed with MG in the active site 2009-04-28 2009-05-12 Odokonyero, D.,Sakai, A.,Patskovsky, Y.,Malashkevich, V.N.,Fedorov, A.A.,Bonanno, J.B.,Fedorov, E.V.,Toro, R.,Agarwal, R.,Wang, C.,Ozerova, N.D.,Yew, W.S.,Sauder, J.M.,Swaminathan, S.,Burley, S.K.,Almo, S.C.,Glasner, M.E. Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proc.Natl.Acad.Sci.USA 2014 111 8535 8540 3H9N Crystal structure of the ribosome maturation factor rimm (hi0203) from h.influenzae. northeast structural genomics consortium target IR66. 2009-04-30 2009-05-19 Kuzin, A.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Maglaqui, M.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target IR66 To be Published 0 0 0 0 3H9W Crystal Structure of the N-terminal domain of Diguanylate cyclase with PAS/PAC sensor (Maqu_2914) from Marinobacter aquaeolei, Northeast Structural Genomics Consortium Target MqR66C 2009-04-30 2009-05-19 Seetharaman, J.,Su, M.,Wang, H.,Foote, E.L.,Mao, L.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target MqR66C To be Published 0 0 0 0 3H9X 22865330 Crystal Structure of the PSPTO_3016 protein from Pseudomonas syringae, Northeast Structural Genomics Consortium Target PsR293 2009-04-30 2009-05-19 Feldmann, E.A.,Seetharaman, J.,Ramelot, T.A.,Lew, S.,Zhao, L.,Hamilton, K.,Ciccosanti, C.,Xiao, R.,Acton, T.B.,Everett, J.K.,Tong, L.,Montelione, G.T.,Kennedy, M.A. Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a ""double wing"" DNA binding motif. J.Struct.Funct.Genom. 2012 13 155 162 3HA2 Crystal Structure of Protein (NADPH-quinone reductase) from P.pentosaceus, Northeast Structural Genomics Consortium Target PtR24A 2009-04-30 2009-05-26 Kuzin, A.,Su, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Maglaqui, M.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target PtR24A To be Published 0 0 0 0 3HBW 19406745 Crystal Structure of Human Fibroblast Growth Factor Homologous Factor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A) 2009-05-05 2009-05-26 Goetz, R.,Dover, K.,Laezza, F.,Shtraizent, N.,Huang, X.,Tchetchik, D.,Eliseenkova, A.V.,Xu, C.F.,Neubert, T.A.,Ornitz, D.M.,Goldfarb, M.,Mohammadi, M. Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels. J.Biol.Chem. 2009 284 17883 17896 3HCS 19465916 Crystal structure of the N-terminal domain of TRAF6 2009-05-06 2009-05-26 Yin, Q.,Lin, S.C.,Lamothe, B.,Lu, M.,Lo, Y.C.,Hura, G.,Zheng, L.,Rich, R.L.,Campos, A.D.,Myszka, D.G.,Lenardo, M.J.,Darnay, B.G.,Wu, H. E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol. 2009 16 658 666 3HCT 19465916 Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group 2009-05-06 2009-05-26 Yin, Q.,Lin, S.C.,Lamothe, B.,Lu, M.,Lo, Y.C.,Hura, G.,Zheng, L.,Rich, R.L.,Campos, A.D.,Myszka, D.G.,Lenardo, M.J.,Darnay, B.G.,Wu, H. E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol. 2009 16 658 666 3HCU 19465916 Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group 2009-05-06 2009-05-26 Yin, Q.,Lin, S.C.,Lamothe, B.,Lu, M.,Lo, Y.C.,Hura, G.,Zheng, L.,Rich, R.L.,Campos, A.D.,Myszka, D.G.,Lenardo, M.J.,Darnay, B.G.,Wu, H. E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol. 2009 16 658 666 3HPA 20088583 Crystal structure of an amidohydrolase gi:44264246 from an evironmental sample of sargasso sea 2009-06-03 2009-06-16 Hall, R.S.,Fedorov, A.A.,Marti-Arbona, R.,Fedorov, E.V.,Kolb, P.,Sauder, J.M.,Burley, S.K.,Shoichet, B.K.,Almo, S.C.,Raushel, F.M. The hunt for 8-oxoguanine deaminase. J.Am.Chem.Soc. 2010 132 1762 1763 3G18 19435314 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2009-01-29 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1A 19435314 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2009-01-29 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1D 19435314 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate 2009-01-29 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1F 19435314 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydroorotidine 5'-monophosphate 2009-01-29 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1H 19435314 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate 2009-01-29 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1S 19435314 Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1V 19435314 Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5-fluorouridine 5'-monophosphate 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1X 19435314 Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G1Y 19435314 Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with sulfate 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G22 19435314 Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3G24 19435314 Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2009-01-30 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3GDK 19435314 Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae 2009-02-24 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3GDL 19435314 Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae complexed with 6-azauridine 5'-monophosphate 2009-02-24 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3GDR 19435314 Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae 2009-02-24 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3GDT 19435314 Crystal structure of the D91N mutant of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae complexed with 6-azauridine 5'-monophosphate 2009-02-24 2009-06-23 Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry 2009 48 5518 5531 3HNR Crystal Structure of a probable methyltransferase BT9727_4108 from Bacillus thuringiensis subsp. Northeast Structural Genomics Consortium target id BuR219 2009-05-31 2009-06-23 Seetharaman, J.,Neely, H.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a probable methyltransferase BT9727_4108 from Bacillus thuringiensis subsp. Northeast Structural Genomics Consortium target id BuR219 To be Published 0 0 0 0 3HT4 Crystal Structure of the Q81A77_BACCR Protein from Bacillus cereus. Northeast Structural Genomics Consortium Target BcR213 2009-06-11 2009-06-23 Vorobiev, S.,Lew, S.,Seetharaman, J.,Wang, H.,Foote, E.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Mao, L.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the Q81A77_BACCR Protein from Bacillus cereus To be Published 0 0 0 0 3HUH The structure of biphenyl-2,3-diol 1,2-dioxygenase iii-related protein from salmonella typhimurium 2009-06-14 2009-06-23 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. The structure of biphenyl-2,3-diol 1,2-dioxygenase iii-related protein from salmonella typhimurium To be Published 0 0 0 0 3FDK 19159332 Crystal structure of hydrolase DR0930 with promiscuous catalytic activity 2008-11-25 2009-06-30 Xiang, D.F.,Kolb, P.,Fedorov, A.A.,Meier, M.M.,Fedorov, L.V.,Nguyen, T.T.,Sterner, R.,Almo, S.C.,Shoichet, B.K.,Raushel, F.M. Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. Biochemistry 2009 48 2237 2247 3G8B 19622680 T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group I222 2009-02-11 2009-06-30 Gregory, S.T.,Demirci, H.,Belardinelli, R.,Monshupanee, T.,Gualerzi, C.,Dahlberg, A.E.,Jogl, G. Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna 2009 15 1693 1704 3H7M 19544572 Crystal Structure of a Histidine Kinase Sensor Domain with Similarity to Periplasmic Binding Proteins 2009-04-27 2009-06-30 Cheung, J.,Le-Khac, M.,Hendrickson, W.A. Crystal structure of a histidine kinase sensor domain with similarity to periplasmic binding proteins. Proteins 2009 77 235 241 3HB9 19523900 Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant 2009-05-04 2009-06-30 Yu, L.P.,Xiang, S.,Lasso, G.,Gil, D.,Valle, M.,Tong, L. A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure 2009 17 823 832 3HNO Crystal Structure of Pyrophosphate-dependent phosphofructokinase from Nitrosospira multiformis. Northeast Structural Genomics Consortium target id NmR42 2009-05-31 2009-06-30 Seetharaman, J.,Abashidze, M.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of Pyrophosphate-dependent phosphofructokinase from Nitrosospira multiformis. Northeast Structural Genomics Consortium target id NmR42 To be Published 0 0 0 0 3HNP Crystal Structure of an Oxidoreductase from Bacillus cereus. Northeast Structural Genomics Consortium target id BcR251 2009-05-31 2009-06-30 Seetharaman, J.,Su, M.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of an Oxidoreductase from Bacillus cereus. Northeast Structural Genomics Consortium target id BcR251 TO BE PUBLISHED 0 0 0 0 3HNQ Crystal Structure of Virulence protein STM3117 from Salmonella typhimurium. Northeast Structural Genomics Consortium target id StR274 2009-05-31 2009-06-30 Seetharaman, J.,Su, M.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of Virulence protein STM3117 from Salmonella typhimurium. Northeast Structural Genomics Consortium target id StR274 To be Published 0 0 0 0 3HO8 19523900 Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A 2009-06-01 2009-06-30 Yu, L.P.,Xiang, S.,Lasso, G.,Gil, D.,Valle, M.,Tong, L. A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure 2009 17 823 832 3HYH 16236260 Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1 2009-06-22 2009-06-30 Rudolph, M.J.,Amodeo, G.A.,Bai, Y.,Tong, L. Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1 Biochem.Biophys.Res.Commun. 2005 337 1224 1228 3HNM Crystal Structure of Protein BT_411 (putative chitobiase, fragment 298-461) from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR319D 2009-05-31 2009-07-07 Kuzin, A.,Abashidze, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target BtR319D To be published 0 0 0 0 3HXK Crystal Structure of a sugar hydrolase (YeeB) from Lactococcus lactis, Northeast Structural Genomics Consortium Target KR108 2009-06-20 2009-07-07 Forouhar, F.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Maglaqui, M.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of a sugar hydrolase (YeeB) from Lactococcus lactis, Northeast Structural Genomics Consortium Target KR108 To be Published 0 0 0 0 3HXP Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577 2009-06-21 2009-07-07 Forouhar, F.,Neely, H.,Seetharaman, J.,Fang, F.,Xiao, R.,Cunningham, K.,Ma, L.,Chen, C.X.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SR577 To be Published 0 0 0 0 3HZE Crystal Structure of Ycf54 protein from Thermosynechococcus elongatus, Northeast Structural Genomics Consortium Target TeR59 2009-06-23 2009-07-07 Kuzin, A.,Abashidze, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target TeR59 To be Published 0 0 0 0 3HMU Crystal structure of a class III aminotransferase from Silicibacter pomeroyi 2009-05-29 2009-07-14 Toro, R.,Bonanno, J.B.,Ramagopal, U.,Freeman, J.,Bain, K.T.,Miller, S.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of a class III aminotransferase from Silicibacter pomeroyi To be Published 0 0 0 0 3I18 Crystal Structure of the PDZ domain of the SdrC-like protein (Lmo2051) from Listeria monocytogenes, Northeast Structural Genomics Consortium Target LmR166B 2009-06-25 2009-07-14 Forouhar, F.,Lew, S.,Seetharaman, J.,Janjua, J.,Xiao, R.,Ciccosanti, C.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target LmR166B To be Published 0 0 0 0 3I4J Crystal structure of Aminotransferase, class III from Deinococcus radiodurans 2009-07-01 2009-07-14 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of Aminotransferase, class III from Deinococcus radiodurans To be Published 0 0 0 0 3I4K Crystal structure of Muconate lactonizing enzyme from Corynebacterium glutamicum 2009-07-01 2009-07-14 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of Muconate lactonizing enzyme from Corynebacterium glutamicum To be Published 0 0 0 0 3I6E CRYSTAL STRUCTURE OF MUCONATE LACTONIZING ENZYME FROM Ruegeria pomeroyi. 2009-07-07 2009-07-14 Fedorov, A.A.,Fedorov, E.V.,Sauder, J.M.,Burley, S.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of muconate lactonizing enzyme from Ruegeria pomeroyi. To be Published 0 0 0 0 3I23 Crystal Structure of an Oxidoreductase (Gfo/Idh/MocA family) from Enterococcus faecalis. Northeast Structural Genomics Consortium target id EfR167 2009-06-29 2009-07-21 Seetharaman, J.,Su, M.,Forouhar, F.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of an Oxidoreductase (Gfo/Idh/MocA family) from Enterococcus faecalis. Northeast Structural Genomics Consortium target id EfR167 To be Published 0 0 0 0 3I24 Crystal Structure of a HIT family hydrolase protein from Vibrio fischeri. Northeast Structural Genomics Consortium target id VfR176 2009-06-29 2009-07-21 Seetharaman, J.,Abashidze, M.,Forouhar, F.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a HIT family hydrolase protein from Vibrio fischeri. Northeast Structural Genomics Consortium target id VfR176 To be Published 0 0 0 0 3F1R 19564416 Crystal structure of FGF20 dimer 2008-10-28 2009-07-28 Kalinina, J.,Byron, S.A.,Makarenkova, H.P.,Olsen, S.K.,Eliseenkova, A.V.,Larochelle, W.J.,Dhanabal, M.,Blais, S.,Ornitz, D.M.,Day, L.A.,Neubert, T.A.,Pollock, P.M.,Mohammadi, M. Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix Mol.Cell.Biol. 2009 29 4663 4678 3HK0 19648926 Crystal Structure of the RA and PH Domains of Grb10 2009-05-22 2009-08-04 Depetris, R.S.,Wu, J.,Hubbard, S.R. Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14. Nat.Struct.Mol.Biol. 2009 16 833 839 3IDU Crystal Structure of the CARDB domain of the PF1109 protein in complex with di-metal ions from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR193A 2009-07-21 2009-08-04 Forouhar, F.,Neely, H.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target PfR193A To be Published 0 0 0 0 3IGF Crystal Structure of the All4481 protein from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR300 2009-07-27 2009-08-04 Forouhar, F.,Abashidze, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Maglaqui, M.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target NsR300 To be Published 0 0 0 0 3E76 19851000 Crystal structure of Wild-type GroEL with bound Thallium ions 2008-08-17 2009-08-25 Kiser, P.D.,Lorimer, G.H.,Palczewski, K. Use of thallium to identify monovalent cation binding sites in GroEL. Acta Crystallogr.,Sect.F 2009 65 967 971 3GC3 19710023 Crystal Structure of Arrestin2S and Clathrin 2009-02-21 2009-08-25 Kang, D.S.,Kern, R.C.,Puthenveedu, M.A.,von Zastrow, M.,Williams, J.C.,Benovic, J.L. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. J.Biol.Chem. 2009 284 29860 29872 3GD1 19710023 Structure of an Arrestin/Clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking 2009-02-23 2009-08-25 Kang, D.S.,Kern, R.C.,Puthenveedu, M.A.,von Zastrow, M.,Williams, J.C.,Benovic, J.L. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking J.Biol.Chem. 2009 284 29860 29872 3HK5 19678710 Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate 2009-05-22 2009-08-25 Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M. The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 2009 48 8879 8890 3HK7 19678710 Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate, monoclinic crystal form 2009-05-22 2009-08-25 Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M. The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 2009 48 8879 8890 3HK8 19678710 Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinohydroxamate 2009-05-22 2009-08-25 Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M. The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 2009 48 8879 8890 3HK9 19678710 Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Glucuronate 2009-05-22 2009-08-25 Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M. The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 2009 48 8879 8890 3HKA 19678710 Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Fructuronate 2009-05-22 2009-08-25 Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M. The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 2009 48 8879 8890 3IHK Crystal Structure of thiamin pyrophosphokinase from S.mutans, Northeast Structural Genomics Consortium Target SmR83 2009-07-30 2009-08-25 Kuzin, A.,Abashidze, M.,Seetharaman, J.,Vorobiev, S.,Mao, M.,Xiao, R.,Ciccosanti, C.,Maglaqui, M.,Foote, E.L.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target SmR83 To be published 0 0 0 0 3FVZ 19604476 Structure of Peptidyl-alpha-hydroxyglycine alpha-Amidating Lyase (PAL) 2009-01-16 2009-09-01 Chufan, E.E.,De, M.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme. Structure 2009 17 965 973 3GIP 19518059 Crystal structure of N-acyl-D-Glutamate Deacylase from Bordetella Bronchiseptica complexed with zinc, acetate and formate ions. 2009-03-05 2009-09-01 Cummings, J.A.,Fedorov, A.A.,Xu, C.,Brown, S.,Fedorov, E.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M. Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily. Biochemistry 2009 48 6469 6481 3GIQ 19518059 Crystal structure of N-acyl-D-Glutamate Deacylase from Bordetella Bronchiseptica complexed with zinc and phosphonate inhibitor, a mimic of the reaction tetrahedral intermediate. 2009-03-05 2009-09-01 Cummings, J.A.,Fedorov, A.A.,Xu, C.,Brown, S.,Fedorov, E.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M. Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily. Biochemistry 2009 48 6469 6481 3JTE Crystal structure of response regulator receiver domain Protein from clostridium thermocellum 2009-09-11 2009-09-22 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of response regulator receiver domain Protein from clostridium thermocellum To be Published 0 0 0 0 3JU5 19783784 Crystal Structure of Dimeric Arginine Kinase at 1.75-A Resolution 2009-09-14 2009-09-29 Wu, X.,Ye, S.,Guo, S.,Yan, W.,Bartlam, M.,Rao, Z. Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J. 2010 24 242 252 3JU5 19783784 Crystal Structure of Dimeric Arginine Kinase at 1.75-A Resolution 2009-09-14 2009-09-29 Wu, X.,Ye, S.,Guo, S.,Yan, W.,Bartlam, M.,Rao, Z. Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity Faseb J. 2010 24 242 252 3JVC Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. Northeast Structural Genomics Consortium Target UuR17a. 2009-09-16 2009-09-29 Vorobiev, S.,Neely, H.,Lee, D.,Ciccosanti, C.,Mao, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published 0 0 0 0 3JVN Crystal Structure of the acetyltransferase VF_1542 from Vibrio fischeri, Northeast Structural Genomics Consortium Target VfR136 2009-09-17 2009-09-29 Forouhar, F.,Neely, H.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target VfR136 To be Published 0 0 0 0 3GBS 19810726 Crystal structure of Aspergillus oryzae cutinase 2009-02-20 2009-10-06 Liu, Z.,Gosser, Y.,Baker, P.J.,Ravee, Y.,Lu, Z.,Alemu, G.,Li, H.,Butterfoss, G.L.,Kong, X.P.,Gross, R.,Montclare, J.K. Structural and functional studies of Aspergillus oryzae cutinase: enhanced thermostability and hydrolytic activity of synthetic ester and polyester degradation. J.Am.Chem.Soc. 2009 131 15711 15716 3I9W 19748340 Crystal structure of the E. coli histidine kinase sensor TorS sensor domain 2009-07-13 2009-10-06 Moore, J.O.,Hendrickson, W.A. Structural analysis of sensor domains from the TMAO-responsive histidine kinase receptor TorS Structure 2009 17 1195 1204 3K25 Crystal Structure of Slr1438 protein from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR112 2009-09-29 2009-10-13 Kuzin, A.,Su, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Belote, R.L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SgR112 To be published 0 0 0 0 3K63 X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. NESG target UuR17a. 2009-10-08 2009-10-20 Vorobiev, S.,Neely, H.,Seetharaman, J.,Lee, D.,Ciccosanti, C.,Mao, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published 0 0 0 0 3K7X Crystal structure of the Lin0763 protein from Listeria innocua. Northeast Structural Genomics Consortium Target LkR23. 2009-10-13 2009-10-27 Vorobiev, S.,Su, M.,Seetharaman, J.,Maglaqui, M.,Ciccosanti, C.,Buchwald, W.A.,Sahdev, S.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Lin0763 protein from Listeria innocua. To be Published 0 0 0 0 3KAT Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E 2009-10-19 2009-10-27 Forouhar, F.,Abashidze, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target HR3486E To be Published 0 0 0 0 3KB2 Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256 2009-10-20 2009-10-27 Forouhar, F.,Friedman, D.,Seetharaman, J.,Janjua, J.,Xiao, R.,Cunningham, K.,Ma, L.,Ho, C.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SR256 To be Published 0 0 0 0 3KBG Crystal structure of the 30S ribosomal protein S4e from Thermoplasma acidophilum. Northeast Structural Genomics Consortium Target TaR28. 2009-10-20 2009-10-27 Vorobiev, S.M.,Su, M.,Seetharaman, J.,Belote, R.L.,Ciccosanti, C.,Liu, J.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the 30S ribosomal protein S4e from Thermoplasma acidophilum. To be Published 0 0 0 0 3K2T Crystal structure of Lmo2511 protein from Listeria monocytogenes, northeast structural genomics consortium target LkR84A 2009-09-30 2009-11-03 Seetharaman, J.,Su, M.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of Lmo2511 protein from Listeria monocytogenes, northeast structural genomics consortium target LkR84A To be Published 0 0 0 0 3HEC 20337484 P38 in complex with Imatinib 2009-05-08 2009-11-10 Namboodiri, H.V.,Bukhtiyarova, M.,Ramcharan, J.,Karpusas, M.,Lee, Y.,Springman, E.B. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry 2010 49 3611 3618 3HEG 20337484 P38 in complex with Sorafenib 2009-05-08 2009-11-10 Namboodiri, H.V.,Bukhtiyarova, M.,Ramcharan, J.,Karpusas, M.,Lee, Y.,Springman, E.B. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry 2010 49 3611 3618 3K2Q Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 2009-09-30 2009-11-17 Seetharaman, J.,Lew, S.,Wang, D.,Neely, H.,Janjua, K.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 To be Published 0 0 0 0 3K2Y Crystal structure of protein lp_0118 from Lactobacillus plantarum,northeast structural genomics consortium target LpR91B 2009-09-30 2009-11-17 Seetharaman, J.,Lew, S.,Vorobiev, S.M.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of protein lp_0118 from Lactobacillus plantarum,northeast structural genomics consortium target LpR91B To be Published 0 0 0 0 3KA7 Crystal Structure of an oxidoreductase from Methanosarcina mazei. Northeast Structural Genomics Consortium target id MaR208 2009-10-18 2009-11-17 Seetharaman, J.,Su, M.,Sahdev, S.,Janjua, H.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of an oxidoreductase from Methanosarcina mazei To be Published 0 0 0 0 3KKJ X-ray structure of P. syringae q888a4 Oxidoreductase at resolution 2.5A, Northeast Structural Genomics Consortium target PsR10 2009-11-05 2009-11-24 Kuzin, A.P.,Chen, Y.,Forouhar, F.,Vorobiev, S.,Acton, T.,Ma, L.C.,Xiao, R.,Montelione, G.T.,Hunt, J.F.,Tong, T. X-ray structure of P. syringae q888a4 Oxidoreductase at resolution 2.5A, Northeast Structural Genomics Consortium target PsR10 To be Published 0 0 0 0 3KKZ Crystal structure of the Q5LES9_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR250. 2009-11-06 2009-11-24 Vorobiev, S.,Neely, H.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Foote, E.L.,Sahdev, S.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the Q5LES9_BACFN protein from Bacteroides fragilis. To be Published 0 0 0 0 3KLU Crystal structure of the protein yqbn. northeast structural genomics consortium target sr445. 2009-11-09 2009-11-24 Kuzin, A.P.,Su, M.,Seetharaman, J.,Wang, D.,Fang, Y.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, M.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the protein yqbn. northeast structural genomics consortium target sr445. To be Published 0 0 0 0 3KNV 19810754 Crystal structure of the RING and first zinc finger domains of TRAF2 2009-11-12 2009-11-24 Yin, Q.,Lamothe, B.,Darnay, B.G.,Wu, H. Structural basis for the lack of E2 interaction in the RING domain of TRAF2. Biochemistry 2009 48 10558 10567 3KOJ Crystal structure of the SSB domain of Q5N255_SYNP6 protein from Synechococcus sp. Northeast Structural Genomics Consortium Target SnR59a. 2009-11-13 2009-11-24 Vorobiev, S.,Su, M.,Seetharaman, J.,Wang, H.,Foote, L.E.,Ciccosanti, C.,Janjua, H.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the SSB domain of Q5N255_SYNP6 protein from Synechococcus sp. To be Published 0 0 0 0 3GHB 19913488 Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020 2009-03-03 2009-12-01 Burke, V.,Williams, C.,Sukumaran, M.,Kim, S.S.,Li, H.,Wang, X.H.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens Structure 2009 17 1538 1546 3GWO 19846514 Structure of the C-terminal Domain of a Putative HIV-1 gp41 Fusion Intermediate 2009-04-01 2009-12-15 Liu, J.,Deng, Y.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M. Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion. J.Virol. 2010 84 201 209 3H01 19846514 Structure of the C-terminal Domain of a Putative HIV-1 gp41 Fusion Intermediate 2009-04-08 2009-12-15 Liu, J.,Deng, Y.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M. Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion. J.Virol. 2010 84 201 209 3GTY 19737520 Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone 2009-03-28 2009-12-22 Martinez-Hackert, E.,Hendrickson, W.A. Promiscuous substrate recognition in folding and assembly activities of the trigger factor chaperone Cell(Cambridge,Mass.) 2009 138 923 934 3GU0 19737520 Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone 2009-03-28 2009-12-22 Martinez-Hackert, E.,Hendrickson, W.A. Promiscuous substrate recognition in folding and assembly activities of the trigger factor chaperone Cell(Cambridge,Mass.) 2009 138 923 934 3HPF 19883118 Crystal structure of the mutant Y90F of divergent galactarate dehydratase from Oceanobacillus iheyensis complexed with Mg and galactarate 2009-06-04 2009-12-22 Rakus, J.F.,Kalyanaraman, C.,Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.P.,Toro, R.,Bonanno, J.,Bain, K.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Jacobson, M.P.,Gerlt, J.A. Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis . Biochemistry 2009 48 11546 11558 3KW6 Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A 2009-11-30 2009-12-22 Seetharaman, J.,Su, M.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,C Baran, M.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A To be Published 0 0 0 0 3ID7 20000809 Crystal structure of renal dipeptidase from Streptomyces coelicolor A3(2) 2009-07-20 2010-01-12 Cummings, J.A.,Nguyen, T.T.,Fedorov, A.A.,Kolb, P.,Xu, C.,Fedorov, E.V.,Shoichet, B.K.,Barondeau, D.P.,Almo, S.C.,Raushel, F.M. Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase . Biochemistry 2010 49 611 622 3K5X 20000809 Crystal structure of dipeptidase from Streptomics coelicolor complexed with phosphinate pseudodipeptide L-Ala-D-Asp at 1.4A resolution. 2009-10-08 2010-01-12 Cummings, J.A.,Nguyen, T.T.,Fedorov, A.A.,Kolb, P.,Xu, C.,Fedorov, E.V.,Shoichet, B.K.,Barondeau, D.P.,Almo, S.C.,Raushel, F.M. Structure, mechanism, and substrate profile for Sco3058: the closest bacterial homologue to human renal dipeptidase . Biochemistry 2010 49 611 622 3L6U Crystal structure of abc-type sugar transport system, Periplasmic component from exiguobacterium sibiricum 2009-12-25 2010-01-12 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of abc-type sugar transport system, Periplasmic component from exiguobacterium sibiricum To be Published 0 0 0 0 3L8D Crystal structure of methyltransferase from Bacillus Thuringiensis 2009-12-30 2010-01-12 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of methyltransferase from Bacillus Thuringiensis To be Published 0 0 0 0 3L6I Crystal structure of the uncharacterized lipoprotein yceb from e. coli at the resolution 2.0a. northeast structural genomics consortium target er542 2009-12-23 2010-01-26 Kuzin, A.P.,Neely, H.,Seetharaman, J.,Chen, C.X.,Janjua, H.,Cunningham, K.,Ma, L.-C.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the uncharacterized lipoprotein yceb from e. coli at the resolution 2.0a. northeast structural genomics consortium target er542 To be Published 0 0 0 0 3GDM Crystal structure of the K93R mutant of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae 2009-02-24 2010-02-09 Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of the K93R mutant of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae. To be Published 0 0 0 0 3L8M Crystal Structure of a probable thiamine pyrophosphokinase from Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Consortium target id SyR86 2009-12-31 2010-02-09 Seetharaman, J.,Lew, S.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of a probable thiamine pyrophosphokinase from Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Consortium target id SyR86 To be Published 0 0 0 0 3LKD Crystal Structure of the type I restriction-modification system methyltransferase subunit from Streptococcus thermophilus, Northeast Structural Genomics Consortium Target SuR80 2010-01-27 2010-02-09 Vorobiev, S.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SuR80 To be published 0 0 0 0 3LKE Crystal structure of enoyl-CoA hydratase from Bacillus halodurans 2010-01-27 2010-02-09 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of enoyl-CoA hydratase from Bacillus halodurans To be Published 0 0 0 0 3LMF Crystal Structure of Nmul_A1745 protein from Nitrosospira multiformis, Northeast Structural Genomics Consortium Target NmR72 2010-01-29 2010-02-16 Forouhar, F.,Lew, S.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target NmR72 To be Published 0 0 0 0 3LMM Crystal Structure of the DIP2311 protein from Corynebacterium diphtheriae, Northeast Structural Genomics Consortium Target CdR35 2010-01-31 2010-02-16 Forouhar, F.,Lew, S.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Buchwald, W.A.,Maglaqui, M.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target CdR35 To be Published 0 0 0 0 3LND 20190754 Crystal structure of cadherin-6 EC12 W4A 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LNE 20190754 Crystal structure of E-cadherin EC12 K14E 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LNF 20190754 Crystal structure of E-cadherin EC12 K14EW2A 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LNG 20190754 Crystal structure of E-cadherin EC12 AA extension 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LNH 20190754 Crystal structure of E-cadherin EC12 W2A 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LNI 20190754 Crystal structure of E-cadherin EC12 E89A 2010-02-02 2010-03-02 Harrison, O.J.,Bahna, F.,Katsamba, P.S.,Jin, X.,Brasch, J.,Vendome, J.,Ahlsen, G.,Carroll, K.J.,Price, S.R.,Honig, B.,Shapiro, L. Two-step adhesive binding by classical cadherins. Nat.Struct.Mol.Biol. 2010 17 348 357 3LV4 Crystal structure of the glycoside hydrolase, family 43 YxiA protein from Bacillus licheniformis. Northeast Structural Genomics Consortium Target BiR14. 2010-02-19 2010-03-09 Vorobiev, S.,Abashidze, M.,Seetharaman, J.,Belote, R.L.,Ciccosanti, C.,Sahdev, S.,Xiao, R.,Acton, T.B.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the glycoside hydrolase, family 43 YxiA protein from Bacillus licheniformis. To be Published 0 0 0 0 3LY0 Crystal structure of metallo peptidase from Rhodobacter sphaeroides liganded with phosphinate mimic of dipeptide L-Ala-D-Ala 2010-02-25 2010-03-09 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of metallo peptidase from Rhodobacter sphaeroides liganded with phosphinate mimic of dipeptide L-Ala-D-Ala To be Published 0 0 0 0 3M3P Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus 2010-03-09 2010-03-23 Fedorov, A.A.,Domagalski, M.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Minor, W.,Almo, S.C. Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus To be Published 0 0 0 0 3M6W 20558545 Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus in space group P21212 in complex with S-Adenosyl-L-Methionine 2010-03-16 2010-03-31 Demirci, H.,Larsen, L.H.,Hansen, T.,Rasmussen, A.,Cadambi, A.,Gregory, S.T.,Kirpekar, F.,Jogl, G. Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus. Rna 2010 16 1584 1596 3L8N Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A 2009-12-31 2010-04-07 Seetharaman, J.,Su, M.,Forouhar, F.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A To be Published 0 0 0 0 3LYW Crystal structure of YbbR family protein Dhaf_0833 from Desulfitobacterium hafniense DCB-2. Northeast Structural Genomics Consortium target id DhR29B 2010-02-28 2010-04-07 Seetharaman, J.,Lew, S.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of YbbR family protein Dhaf_0833 from Desulfitobacterium hafniense DCB-2. Northeast Structural Genomics Consortium target id DhR29B To be Published 0 0 0 0 3LYX Crystal structure of the PAS domain of the protein CPS_1291 from Colwellia psychrerythraea. Northeast Structural Genomics Consortium target id CsR222B 2010-02-28 2010-04-07 Seetharaman, J.,Chen, Y.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the PAS domain of the protein CPS_1291 from Colwellia psychrerythraea. Northeast Structural Genomics Consortium target id CsR222B To be Published 0 0 0 0 3LYY Crystal structure of the MucBP domain of the adhesion protein PEPE_0118 from Pediococcus pentosaceus. Northeast Structural Genomics Consortium target id PtR41A 2010-02-28 2010-04-07 Seetharaman, J.,Lew, S.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the MucBP domain of the adhesion protein PEPE_0118 from Pediococcus pentosaceus. Northeast Structural Genomics Consortium target id PtR41A To be Published 0 0 0 0 3M7V Crystal structure of phosphopentomutase from streptococcus mutans 2010-03-17 2010-04-07 Fedorov, A.A.,Bonanno, J.,Fedorov, E.V.,Burley, S.K.,Almo, S.C. Crystal structure of phosphopentomutase from streptococcus mutans To be Published 0 0 0 0 3MCU Crystal structure of the dipicolinate synthase chain B from Bacillus cereus. Northeast Structural Genomics Consortium Target BcR215. 2010-03-29 2010-04-14 Vorobiev, S.,Lew, S.,Abashidze, M.,Seetharaman, J.,Wang, H.,Ciccosanti, C.,Foote, E.L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the dipicolinate synthase chain B from Bacillus cereus. To be Published 0 0 0 0 3MER Crystal Structure of the methyltransferase Slr1183 from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR145 2010-03-31 2010-04-14 Seetharaman, J.,Chen, Y.,Forouhar, F.,Rossi, P.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Belote, R.L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target SgR145 To be Published 0 0 0 0 3MFX Crystal Structure of the sensory box domain of the sensory-box/GGDEF protein SO_1695 from Shewanella oneidensis, Northeast Structural Genomics Consortium Target SoR288B 2010-04-04 2010-04-14 Forouhar, F.,Abashidze, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SoR288B To be Published 0 0 0 0 3H0Q 20219367 Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 3 2009-04-10 2010-04-21 Corbett, J.W.,Freeman-Cook, K.D.,Elliott, R.,Vajdos, F.,Rajamohan, F.,Kohls, D.,Marr, E.,Zhang, H.,Tong, L.,Tu, M.,Murdande, S.,Doran, S.D.,Houser, J.A.,Song, W.,Jones, C.J.,Coffey, S.B.,Buzon, L.,Minich, M.L.,Dirico, K.J.,Tapley, S.,McPherson, R.K.,Sugarman, E.,Harwood, H.J.,Esler, W. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg.Med.Chem.Lett. 2010 20 2383 2388 3MGY 17441692 Mutagenesis of p38 MAP Kinase eshtablishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state 2010-04-07 2010-04-21 Bukhtiyarova, M.,Karpusas, M.,Northrop, K.,Namboodiri, H.V.,Springman, E.B. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry 2007 46 5687 5696 3MH0 17441692 Mutagenesis of p38 MAP Kinase eshtablishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state 2010-04-07 2010-04-21 Bukhtiyarova, M.,Karpusas, M.,Northrop, K.,Namboodiri, H.V.,Springman, E.B. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry 2007 46 5687 5696 3MH1 17441692 Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state 2010-04-07 2010-04-21 Bukhtiyarova, M.,Karpusas, M.,Northrop, K.,Namboodiri, H.V.,Springman, E.B. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry 2007 46 5687 5696 3MH2 17441692 Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state 2010-04-07 2010-04-21 Bukhtiyarova, M.,Karpusas, M.,Northrop, K.,Namboodiri, H.V.,Springman, E.B. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry 2007 46 5687 5696 3MH3 17441692 Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state 2010-04-07 2010-04-21 Bukhtiyarova, M.,Karpusas, M.,Northrop, K.,Namboodiri, H.V.,Springman, E.B. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry 2007 46 5687 5696 3MD2 Crystal structure of the matrix protein 1 from influenza A virus (A/California/04/2009 (H1N1)) 2010-03-29 2010-04-28 Liu, Q.,Kloss, B.,SKOWRONSKI, E.S.,Height, J.,Love, J. Crystal structure of the matrix protein 1 from influenza A virus (A/California/04/2009 (H1N1)) To be Published 0 0 0 0 3LI8 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase mmHK1S-Z2 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LI9 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase mmHK1S-Z2 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LIA 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase mmHK1S-Z2 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LIB 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase mmHK1S-Z3 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LIC 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase soHK1S-Z6 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LID 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase vpHK1S-Z8 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LID 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase vpHK1S-Z8 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LIE 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase vpHK1S-Z8 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3LIF 20435045 Crystal Structure of the extracellular domain of the putative histidine kinase rpHK1S-Z16 2010-01-24 2010-05-05 Zhang, Z.,Hendrickson, W.A. Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol. 2010 400 335 353 3M3R 20400691 Crystal structure of the M113F alpha-hemolysin mutant complexed with beta-cyclodextrin 2010-03-09 2010-05-05 Banerjee, A.,Mikhailova, E.,Cheley, S.,Gu, L.Q.,Montoya, M.,Nagaoka, Y.,Gouaux, E.,Bayley, H. Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc.Natl.Acad.Sci.USA 2010 107 8165 8170 3M4D 20400691 Crystal structure of the M113N mutant of alpha-hemolysin 2010-03-10 2010-05-05 Banerjee, A.,Mikhailova, E.,Cheley, S.,Gu, L.Q.,Montoya, M.,Nagaoka, Y.,Gouaux, E.,Bayley, H. Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc.Natl.Acad.Sci.USA 2010 107 8165 8170 3M4E 20400691 Crystal structure of the M113N mutant of alpha-hemolysin bound to beta-cyclodextrin 2010-03-10 2010-05-05 Banerjee, A.,Mikhailova, E.,Cheley, S.,Gu, L.Q.,Montoya, M.,Nagaoka, Y.,Gouaux, E.,Bayley, H. Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc.Natl.Acad.Sci.USA 2010 107 8165 8170 3KPH 20417218 Crystal structure of Mycoplasma arthritidis-derived mitogen 2009-11-16 2010-05-12 Liu, L.,Li, Z.,Guo, Y.,Vanvranken, S.J.,Mourad, W.,Li, H. Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer. J.Mol.Biol. 2010 399 367 376 3M2L 20400691 Crystal structure of the M113F mutant of alpha-hemolysin 2010-03-07 2010-05-12 Banerjee, A.,Mikhailova, E.,Cheley, S.,Gu, L.Q.,Montoya, M.,Nagaoka, Y.,Gouaux, E.,Bayley, H. Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc.Natl.Acad.Sci.USA 2010 107 8165 8170 3M70 Crystal Structure of TehB from Haemophilus influenzae 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of TehB from Haemophilus influenzae To be Published 0 0 0 0 3M71 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3M72 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M73 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3M74 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3M75 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3M76 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3M77 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M78 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M7B Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hu, L.,Siegelbaum, S.A.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M7C Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M7E Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.-H.,Hendrickson, W.A. Crystal Structure of Plant SLAC1 homolog TehA To be Published 0 0 0 0 3M7L 20981093 Crystal Structure of Plant SLAC1 homolog TehA 2010-03-16 2010-05-12 Chen, Y.H.,Hu, L.,Punta, M.,Bruni, R.,Hillerich, B.,Kloss, B.,Rost, B.,Love, J.,Siegelbaum, S.A.,Hendrickson, W.A. Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 467 1074 1080 3LYV Crystal structure of a domain of ribosome-associated factor Y from streptococcus pyogenes serotype M6. Northeast Structural Genomics Consortium target id DR64A 2010-02-28 2010-05-26 Seetharaman, J.,Neely, H.,Forouhar, F.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of a domain of ribosome-associated factor Y from streptococcus pyogenes serotype M6. Northeast Structural Genomics Consortium target id DR64A To be Published 0 0 0 0 3MPR Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A 2010-04-27 2010-05-26 Kuzin, A.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Northeast Structural Genomics Consortium Target BtR318A To be Published 0 0 0 0 3MTK X-Ray Structure of Diguanylate cyclase/phosphodiesterase from Caldicellulosiruptor saccharolyticus, Northeast Structural Genomics Consortium Target ClR27C 2010-04-30 2010-06-02 Kuzin, A.,Abashidze, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target ClR27C To be Published 0 0 0 0 3LHT 20369850 Crystal structure of the mutant V201F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LHU 20369850 Crystal structure of the mutant I199F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LHV 20369850 Crystal structure of the mutant V182A.I199A.V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LHW 20369850 Crystal structure of the mutant V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LHY 20369850 Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LHZ 20369850 Crystal structure of the mutant V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LI0 23030629 Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3LI1 20369850 Crystal structure of the mutant I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-01-23 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LLD 20369850 Crystal structure of the mutant S127G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-01-28 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LLF 20369850 Crystal structure of the mutant S127P of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-01-29 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LTP 20369850 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-02-16 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LTS 20369850 Crystal structure of the mutant V182A,I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-02-16 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LTY 20369850 Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-02-16 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LV5 20369850 Crystal structure of the mutant I199E of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-02-19 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3LV6 20369850 Crystal structure of the mutant I218F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-02-19 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M1Z 20369850 Crystal structure of the mutant V182A.V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-03-06 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M41 20369850 Crystal structure of the mutant V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-10 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M43 20369850 Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-10 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M44 20369850 Crystal structure of the mutant V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-10 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M47 20369850 Crystal structure of the mutant I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-10 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M5X 20369850 Crystal structure of the mutant V182A,I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-14 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M5Y 20369850 Crystal structure of the mutant V182A,V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-14 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3M5Z 20369850 Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum 2010-03-14 2010-06-16 Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: ""remote"" residues that stabilize the active conformation. Biochemistry 2010 49 3514 3516 3NEH Crystal structure of the protein LMO2462 from Listeria monocytogenes complexed with ZN and phosphonate mimic of dipeptide L-Leu-D-Ala 2010-06-08 2010-06-30 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of the protein LMO2462 from Listeria monocytogenes complexed with ZN and phosphonate mimic of dipeptide L-Leu-D-Ala To be Published 0 0 0 0 3MLR 20622876 Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a NY5 V3 peptide 2010-04-18 2010-07-14 Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol. 2010 17 955 961 3MLU 20622876 Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a ZAM18 V3 peptide 2010-04-18 2010-07-14 Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol. 2010 17 955 961 3MLV 20622876 Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with an NOF V3 peptide 2010-04-18 2010-07-14 Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol. 2010 17 955 961 3MLZ 20622876 Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a VI191 V3 peptide 2010-04-18 2010-07-14 Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol. 2010 17 955 961 3NNQ 28066922 Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 2010-06-24 2010-07-14 Guan, R.,Aiyer, S.,Cote, M.L.,Xiao, R.,Jiang, M.,Acton, T.B.,Roth, M.J.,Montelione, G.T. X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins 2017 85 647 656 3IJI 22392983 Structure of dipeptide epimerase from Bacteroides thetaiotaomicron complexed with L-Ala-D-Glu; nonproductive substrate binding. 2009-08-04 2010-07-21 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3IJL 22392983 Structure of dipeptide epimerase from Bacteroides thetaiotaomicron complexed with L-Pro-D-Glu; nonproductive substrate binding. 2009-08-04 2010-07-21 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3IJQ 22392983 Structure of dipeptide epimerase from Bacteroides thetaiotaomicron complexed with L-Ala-D-Glu; productive substrate binding. 2009-08-04 2010-07-21 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3LS9 Crystal structure of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc 2010-02-12 2010-07-21 Fedorov, A.A.,Fedorov, E.V.,Seffernick, J.,Wackett, L.P.,Almo, S.C. Crystal structure of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc To be Published 0 0 0 0 3LSB Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and ametrin 2010-02-12 2010-07-21 Fedorov, A.A.,Fedorov, E.V.,Seffernick, J.,Wackett, L.P.,Almo, S.C. Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and Ametryn To be Published 0 0 0 0 3LSC Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and atraton 2010-02-12 2010-07-21 Fedorov, A.A.,Fedorov, E.V.,Seffernick, J.,Wackett, L.P.,Almo, S.C. Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and atraton To be Published 0 0 0 0 3MTW 20604542 Crystal structure of L-Lysine, L-Arginine carboxypeptidase Cc2672 from Caulobacter Crescentus CB15 complexed with N-methyl phosphonate derivative of L-Arginine 2010-05-01 2010-07-28 Xiang, D.F.,Patskovsky, Y.,Xu, C.,Fedorov, A.A.,Fedorov, E.V.,Sisco, A.A.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Raushel, F.M. Functional Identification and Structure Determination of Two Novel Prolidases from cog1228 in the Amidohydrolase Superfamily Biochemistry 2010 49 6791 6803 3MW3 20624592 Crystal structure of beta-neurexin 2 with the splice insert 4 2010-05-05 2010-07-28 Koehnke, J.,Katsamba, P.S.,Ahlsen, G.,Bahna, F.,Vendome, J.,Honig, B.,Shapiro, L.,Jin, X. Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions. Neuron 2010 67 61 74 3NWR Crystal structure of a rubisco-like protein from Burkholderia fungorum 2010-07-10 2010-07-28 Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Gerlt, J.A.,Almo, S.C. Crystal structure of a rubisco-like protein from Burkholderia fungorum To be Published 0 0 0 0 3NXL Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium 2010-07-14 2010-07-28 Fedorov, A.A.,Fedorov, E.V.,Gerlt, J.A.,Burley, S.K.,Almo, S.C. Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium To be Published 0 0 0 0 3NY5 Crystal structure of the RBD domain of serine/threonine-protein kinase B-raf from Homo sapiens. Northeast Structural Genomics Consortium Target HR4694F 2010-07-14 2010-07-28 Vorobiev, S.,Su, M.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal structure of the RBD domain of serine/threonine-protein kinase B-raf from Homo sapiens. To be Published 0 0 0 0 3LKZ 20685660 Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase 2010-01-28 2010-08-04 Dong, H.,Liu, L.,Zou, G.,Zhao, Y.,Li, Z.,Lim, S.P.,Shi, P.Y.,Li, H. Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase. J.Biol.Chem. 2010 285 32586 32595 3NRO Crystal Structure of putative transcriptional factor Lmo1026 from Listeria monocytogenes (FRAGMENT 52-321), Northeast Structural Genomics Consortium Target LmR194 2010-06-30 2010-08-04 Kuzin, A.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target LmR194 To be Published 0 0 0 0 3NXH Crystal Structure of the transcriptional regulator yvhJ from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR735. 2010-07-13 2010-08-04 Vorobiev, S.,Chen, Y.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the transcriptional regulator yvhJ from Bacillus subtilis. To be Published 0 0 0 0 3JVA 22392983 Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 2009-09-16 2010-08-11 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3JW7 22392983 Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Ile-L-Tyr 2009-09-18 2010-08-11 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3NGW Crystal Structure of Molybdopterin-guanine dinucleotide biosynthesis protein A from Archaeoglobus fulgidus, Northeast Structural Genomics Consortium Target GR189 2010-06-13 2010-08-11 Forouhar, F.,Neely, H.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target GR189 To be Published 0 0 0 0 3NNN 20702407 BeF3 Activated DrrD Receiver Domain 2010-06-23 2010-08-11 Barbieri, C.M.,Mack, T.R.,Robinson, V.L.,Miller, M.T.,Stock, A.M. Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem. 2010 285 32325 32335 3NNS 20702407 BeF3 Activated DrrB Receiver Domain 2010-06-24 2010-08-11 Barbieri, C.M.,Mack, T.R.,Robinson, V.L.,Miller, M.T.,Stock, A.M. Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem. 2010 285 32325 32335 3O6U Crystal Structure of CPE2226 protein from Clostridium perfringens. Northeast Structural Genomics Consortium Target CpR195 2010-07-29 2010-08-11 Vorobiev, S.,Su, M.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of CPE2226 protein from Clostridium perfringens. To be Published 0 0 0 0 3JZU 22392983 Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Leu-L-Tyr 2009-09-24 2010-08-18 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3K1G 22392983 Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Ser-L-Tyr 2009-09-27 2010-08-18 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3NLC Crystal structure of the VP0956 protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium Target VpR147 2010-06-21 2010-08-18 Vorobiev, S.,Neely, H.,Seetharaman, J.,Wang, D.,Mao, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J. Crystal structure of the VP0956 protein from Vibrio parahaemolyticus. To be Published 0 0 0 0 3NRH Crystal Structure of protein BF1032 from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR309 2010-06-30 2010-08-25 Seetharaman, J.,Lew, S.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target BfR309 To be Published 2010 0 0 0 3NRW Crystal Structure of the N-terminal domain of Phage integrase/site-specific recombinase (tnp) from Haloarcula marismortui, Northeast Structural Genomics Consortium Target HmR208A 2010-06-30 2010-08-25 Forouhar, F.,Su, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target HmR208A To be Published 0 0 0 0 3OBG Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding 2010-08-06 2010-08-25 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published 0 0 0 0 3OC1 Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding 2010-08-09 2010-08-25 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published 0 0 0 0 3O8P Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding 2010-08-03 2010-09-01 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published 0 0 0 0 3O8U Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding 2010-08-03 2010-09-01 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published 0 0 0 0 3OH8 Crystal structure of the nucleoside-diphosphate sugar epimerase from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR91 2010-08-17 2010-09-01 Vorobiev, S.,Lew, S.,Kuzin, A.,Mao, M.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the nucleoside-diphosphate sugar epimerase from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR91. To be Published 0 0 0 0 3OHW X-Ray Structure of Phycobilisome LCM core-membrane linker polypeptide (fragment 721-860) from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR209E 2010-08-18 2010-09-01 Kuzin, A.,Su, M.,Lew, S.,Vorobiev, S.M.,Patel, P.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target SgR209E To be Published 0 0 0 0 3NWZ Crystal Structure of BH2602 protein from Bacillus halodurans with CoA, Northeast Structural Genomics Consortium Target BhR199 2010-07-12 2010-09-08 Kuzin, A.,Su, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target BhR199 To be published 0 0 0 0 3MPA Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding 2010-04-26 2010-09-15 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding TO BE PUBLISHED 0 0 0 0 3LLY 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3LLY 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3LLZ 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin complex with Gal-beta-1,3-GalNAc 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3LLZ 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin complex with Gal-beta-1,3-GalNAc 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3LM1 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin complex with p-nitrophenyl-GalNAc 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3LM1 20826825 Crystal Structure Analysis of Maclura pomifera agglutinin complex with p-nitrophenyl-GalNAc 2010-01-29 2010-09-22 Huang, J.,Xu, Z.,Wang, D.,Ogata, C.M.,Palczewski, K.,Lee, X.,Young, N.M. Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology 2010 20 1643 1653 3NZL Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B 2010-07-16 2010-09-22 Forouhar, F.,Abashidze, M.,Seetharaman, J.,Kuzin, A.P.,Patel, P.,Xiao, R.,Ciccosanti, C.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B (CASP Target) To be Published 0 0 0 0 3OKZ Crystal Structure of protein gbs0355 from Streptococcus agalactiae, Northeast Structural Genomics Consortium Target SaR127 2010-08-25 2010-09-22 Kuzin, A.,Lew, S.,Vorobiev, S.M.,Seetharaman, J.,Janjua, J.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target SaR127 To be Published 0 0 0 0 3OTL Three-dimensional Structure of the putative uncharacterized protein from Rhizobium leguminosarum at the resolution 1.9A, Northeast Structural Genomics Consortium Target RlR261 2010-09-13 2010-09-22 Kuzin, A.,Lew, S.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Northeast Structural Genomics Consortium Target RlR261 To be Published 0 0 0 0 3L8P Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207 2010-01-03 2010-10-06 Fedorov, A.A.,Fedorov, E.V.,Pauletti, D.,Meyer, S.L.,Hudkins, R.L.,Almo, S.C. Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207 To be Published 0 0 0 0 3OSJ X-Ray Structure of Phycobilisome LCM core-membrane linker polypeptide (fragment 254-400) from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR209C 2010-09-09 2010-10-06 Kuzin, A.,Su, M.,Lew, S.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SgR209C To be published 0 0 0 0 3KUM 22392983 Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Arg-L-Tyr 2009-11-27 2010-10-13 Lukk, T.,Sakai, A.,Kalyanaraman, C.,Brown, S.D.,Imker, H.J.,Song, L.,Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Hillerich, B.,Seidel, R.,Patskovsky, Y.,Vetting, M.W.,Nair, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A.,Jacobson, M.P. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA 2012 109 4122 4127 3P04 Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8 2010-09-27 2010-10-13 Vorobiev, S.,Lew, S.,Seetharaman, J.,Hamilton, H.,Xiao, R.,Patel, D.J.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8. To be Published 0 0 0 0 3P0W Crystal structure of D-Glucarate dehydratase from Ralstonia solanacearum complexed with Mg and D-glucarate 2010-09-29 2010-10-13 Fedorov, A.A.,Fedorov, E.V.,Gerlt, J.A.,Burley, S.K.,Almo, S.C. Crystal structure of D-Glucarate dehydratase from Ralstonia solanacearum complexed with Mg and D-glucarate To be Published 0 0 0 0 3NRN Crystal Structure of PF1083 protein from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR223 2010-06-30 2010-11-03 Seetharaman, J.,Su, M.,Patel, P.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target PfR223 To be Published 0 0 0 0 3PE5 Three-dimensional Structure of protein A7VV38_9CLOT from Clostridium leptum DSM 753, Northeast Structural Genomics Consortium Target QlR103 2010-10-25 2010-11-10 Kuzin, A.,Su, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target QlR103 To be published 0 0 0 0 3O8T Conformational plasticity of p38 MAP kinase DFG-motif mutants in response to inhibitor binding 2010-08-03 2010-11-17 Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding To be Published 0 0 0 0 3PDW Crystal structure of putative p-nitrophenyl phosphatase from Bacillus subtilis 2010-10-25 2010-11-17 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Sauder, J.M.,Burley, S.K.,Almo, S.C. Crystal structure of putative p-nitrophenyl phosphatase from Bacillus subtilis To be Published 0 0 0 0 3PRU Crystal Structure of Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 1 (fragment 14-158) from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR182A 2010-11-30 2010-12-15 Kuzin, A.,Su, M.,Patel, P.,Xiao, R.,Ciccosanti, C.,Lee, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target SgR182A To be Published 0 0 0 0 3P1X Crystal structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E 2010-09-30 2010-12-29 Seetharaman, J.,Neely, H.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E To be Published 0 0 0 0 3Q63 X-ray crystal structure of protein MLL2253 from Mesorhizobium loti, Northeast Structural Genomics Consortium Target MlR404. 2010-12-30 2011-01-12 Forouhar, F.,Lew, S.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray crystal structure of protein MLL2253 from Mesorhizobium loti, Northeast Structural Genomics Consortium Target MlR404. To be Published 0 0 0 0 3Q64 X-ray crystal structure of protein mll3774 from Mesorhizobium loti, Northeast Structural Genomics Consortium Target MlR405. 2010-12-30 2011-01-12 Forouhar, F.,Lew, S.,Seetharaman, J.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L. X-ray crystal structure of protein mll3774 from Mesorhizobium loti, Northeast Structural Genomics Consortium Target MlR405. To be Published 0 0 0 0 3PR9 21262232 Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 2010-11-29 2011-01-19 Martinez-Hackert, E.,Hendrickson, W.A. Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol. 2011 407 450 464 3PRA 21262232 Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 2010-11-29 2011-01-19 Martinez-Hackert, E.,Hendrickson, W.A. Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol. 2011 407 450 464 3PRB 21262232 Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 2010-11-29 2011-01-19 Martinez-Hackert, E.,Hendrickson, W.A. Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol. 2011 407 450 464 3PRB 21262232 Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 2010-11-29 2011-01-19 Martinez-Hackert, E.,Hendrickson, W.A. Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol. 2011 407 450 464 3PRD 21262232 Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 2010-11-29 2011-01-19 Martinez-Hackert, E.,Hendrickson, W.A. Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol. 2011 407 450 464 3QFW Crystal structure of Rubisco-like protein from Rhodopseudomonas palustris 2011-01-23 2011-02-09 Fedorov, A.A.,Fedorov, E.V.,Gerlt, J.A.,Burley, S.K.,Almo, S.C. Crystal structure of Rubisco-like protein from Rhodopseudomonas palustris To be Published 0 0 0 0 3MDU 25559274 The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutamate 2010-03-30 2011-03-09 Fedorov, A.A.,Marti-Arbona, R.,Nemmara, V.V.,Hitchcock, D.,Fedorov, E.V.,Almo, S.C.,Raushel, F.M. Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa. Biochemistry 2015 54 890 897 3MDW 25559274 The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate 2010-03-30 2011-03-09 Fedorov, A.A.,Marti-Arbona, R.,Nemmara, V.V.,Hitchcock, D.,Fedorov, E.V.,Almo, S.C.,Raushel, F.M. Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa. Biochemistry 2015 54 890 897 3PQ1 21292163 Crystal structure of human mitochondrial poly(A) polymerase (PAPD1) 2010-11-25 2011-03-30 Bai, Y.,Srivastava, S.K.,Chang, J.H.,Manley, J.L.,Tong, L. Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. Mol.Cell 2011 41 311 320 3Q2V 21300292 Crystal structure of mouse E-cadherin ectodomain 2010-12-20 2011-04-06 Harrison, O.J.,Jin, X.,Hong, S.,Bahna, F.,Ahlsen, G.,Brasch, J.,Wu, Y.,Vendome, J.,Felsovalyi, K.,Hampton, C.M.,Troyanovsky, R.B.,Ben-Shaul, A.,Frank, J.,Troyanovsky, S.M.,Shapiro, L.,Honig, B. The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure 2011 19 244 256 3Q69 X-ray crystal structure of a MucBP domain of the protein LBA1460 from Lactobacillus acidophilus, Northeast structural genomics consortium target LaR80A 2010-12-31 2011-04-06 Seetharaman, J.,Lew, S.,Forouhar, F.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. X-ray crystal structure of a MucBP domain of the protein LBA1460 from Lactobacillus acidophilus, Northeast structural genomics consortium target LaR80A To be Published 0 0 0 0 3Q6A X-ray crystal structure of the protein SSP2350 from Staphylococcus saprophyticus, Northeast structural genomics consortium target SyR116 2010-12-31 2011-04-06 Seetharaman, J.,Chen, Y.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) X-ray crystal structure of the protein SSP2350 from Staphylococcus saprophyticus, Northeast structural genomics consortium target SyR116 To be Published 0 0 0 0 3QSZ Crystal Structure of the STAR-related lipid transfer protein (fragment 25-204) from Xanthomonas axonopodis at the resolution 2.4A, Northeast Structural Genomics Consortium Target XaR342 2011-02-22 2011-04-20 Kuzin, A.P.,Su, M.,Vorobiev, S.M.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target XaR342 To be Published 0 0 0 0 3NQ6 Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP 2010-06-29 2011-05-11 A Fedorov, A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP To be Published 0 0 0 0 3NQ7 Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP To be Published 0 0 0 0 3NQA Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 A Fedorov, A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP To be Published 0 0 0 0 3NQC 21870810 Crystal structure of the mutant I96S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3NQD 21870810 Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3NQE 21870810 Crystal structure of the mutant L123N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3NQF 21870810 Crystal structure of the mutant L123S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3NQG 21870810 Crystal structure of the mutant V155D of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3NQM 21870810 Crystal structure of the mutant V155S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-06-29 2011-05-11 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3RJZ 22102225 X-ray crystal structure of the putative n-type atp pyrophosphatase from pyrococcus furiosus, the northeast structural genomics target pfr23 2011-04-16 2011-05-11 Forouhar, F.,Saadat, N.,Hussain, M.,Seetharaman, J.,Lee, I.,Janjua, H.,Xiao, R.,Shastry, R.,Acton, T.B.,Montelione, G.T.,Tong, L. A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding. Acta Crystallogr.,Sect.F 2011 67 1323 1327 3RK1 22102225 'X-ray crystal Structure of the putative N-type ATP pyrophosphatase (PF0828) in complex with ATP from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR23 2011-04-16 2011-05-11 Forouhar, F.,Saadat, N.,Hussain, M.,Seetharaman, J.,Lee, I.,Janjua, H.,Xiao, R.,Shastry, R.,Acton, T.B.,Montelione, G.T.,Tong, L. A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding. Acta Crystallogr.,Sect.F 2011 67 1323 1327 3QRB 21572446 crystal structure of E-cadherin EC1-2 P5A P6A 2011-02-17 2011-05-18 Vendome, J.,Posy, S.,Jin, X.,Bahna, F.,Ahlsen, G.,Shapiro, L.,Honig, B. Molecular design principles underlying beta-strand swapping in the adhesive dimerization of cadherins. Nat.Struct.Mol.Biol. 2011 18 693 700 3RUP 21592965 Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions 2011-05-05 2011-05-18 Chou, C.Y.,Tong, L. Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem. 2011 286 24417 24425 3RV3 21592965 Crystal structure of E.coli biotin carboxylase in complex with two ADP and one Mg ion 2011-05-05 2011-05-18 Chou, C.Y.,Tong, L. Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem. 2011 286 24417 24425 3RV4 21592965 Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate 2011-05-05 2011-05-18 Chou, C.Y.,Tong, L. Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem. 2011 286 24417 24425 3RD4 Crystal structure of PROPEN_03304 from Proteus penneri ATCC 35198 Northeast Structural Genomics Consortium target id PvR55 2011-03-31 2011-05-25 Seetharaman, J.,Min, S.,Kuzin, A.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal structure of PROPEN_03304 from Proteus penneri ATCC 35198 Northeast Structural Genomics Consortium target id PvR55 To be Published 0 0 0 0 3RD6 Crystal structure of Mll3558 protein from Rhizobium loti. Northeast Structural Genomics Consortium target id MlR403 2011-04-01 2011-05-25 Seetharaman, J.,Chen, Y.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal structure of Mll3558 protein from Rhizobium loti. Northeast Structural Genomics Consortium target id MlR403 To be Published 0 0 0 0 3P7K GP41 peptide 2010-10-12 2011-06-08 0 0 0 0 3O7U 21545144 Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with zinc and phosphono-cytosine 2010-07-31 2011-06-15 Hall, R.S.,Fedorov, A.A.,Xu, C.,Fedorov, E.V.,Almo, S.C.,Raushel, F.M. Three-dimensional structure and catalytic mechanism of Cytosine deaminase. Biochemistry 2011 50 5077 5085 3S2J Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Leu-D-Ala 2011-05-16 2011-06-22 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Almo, S.C. Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Leu-D-Ala To be Published 0 0 0 0 3S2L Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Leu-D-Glu 2011-05-16 2011-06-22 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Almo, S.C. Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Leu-D-Glu To be Published 0 0 0 0 3S2M Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Phe-D-Asp 2011-05-16 2011-06-22 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Almo, S.C. Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Phe-D-Asp To be Published 0 0 0 0 3S2N Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Tyr-D-Asp 2011-05-16 2011-06-22 Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Almo, S.C. Crystal structure of dipeptidase from Streptomyces coelicolor complexed with phosphinate pseudodipeptide L-Tyr-D-Asp To be Published 0 0 0 0 3P3B CRYSTAL STRUCTURE OF Galacturonate DEHYDRATASE FROM GEOBACILLUS SP. COMPLEXED WITH D-TARTRATE 2010-10-04 2011-06-29 Fedorov, A.A.,Fedorov, E.V.,Groninger-Poe, F.,Gerlt, J.A.,Burley, S.K.,Almo, S.C. CRYSTAL STRUCTURE OF Galacturonate DEHYDRATASE FROM GEOBACILLUS SP. COMPLEXED WITH D-TARTRATE. To be Published 0 0 0 0 3SIZ Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-06-20 2011-06-29 Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP To be Published 0 0 0 0 3SJ3 23030629 Crystal structure of the mutant R160A.Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-06-20 2011-06-29 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3SLR Crystal structure of N-terminal part of the protein BF1531 from Bacteroides fragilis containing phosphatase domain complexed with Mg. 2011-06-24 2011-07-20 Fedorov, A.A.,Fedorov, E.V.,Toro, R.,Burley, S.K.,Almo, S.C. Crystal structure of N-terminal part of the protein BF1531 from Bacteroides fragilis containing phosphatase domain complexed with Mg. TO BE PUBLISHED 0 0 0 0 3SYX Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein. Northeast Structural Genomics Consortium Target HR5538B. 2011-07-18 2011-08-03 Vorobiev, S.,Su, M.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Shastry, R.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein. To be Published 0 0 0 0 3OTT 24995510 Crystal Structure of the extracellular domain of the putative one component system BT4673 from B. thetaiotaomicron 2010-09-13 2011-08-10 Zhang, Z.,Liu, Q.,Hendrickson, W.A. Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont. Febs J. 2014 281 4263 4279 3Q6C X-ray crystal structure of duf2500 (pf10694) from klebsiella pneumoniae, northeast structural genomics consortium target kpr96 2010-12-31 2011-08-10 Seetharaman, J.,Su, M.,Wang, D.,Ciccosanti, C.,Sahdev, S.,Nair, R.,Rost, B.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) X-ray crystal structure of duf2500 (pf10694) from klebsiella pneumoniae, northeast structural genomics consortium target kpr96 To be Published 0 0 0 0 3RN6 21604715 Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with zinc and isoguanine 2011-04-22 2011-08-24 Hitchcock, D.S.,Fedorov, A.A.,Fedorov, E.V.,Dangott, L.J.,Almo, S.C.,Raushel, F.M. Rescue of the orphan enzyme isoguanine deaminase. Biochemistry 2011 50 5555 5557 3SWV Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A 2011-07-14 2011-08-24 Seetharaman, J.,Su, M.,Forouhar, F.,Wang, D.,Janjua, H.,Cunningham, K.,Owens, L.,Xiao, R.,Liu, J.,Baran, M.C.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A To be Published 0 0 0 0 3OJ2 22057274 Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation 2010-08-20 2011-08-31 Beenken, A.,Eliseenkova, A.V.,Ibrahimi, O.A.,Olsen, S.K.,Mohammadi, M. Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem. 2012 287 3067 3078 3OJM 22057274 Crystal Structure of FGF1 complexed with the ectodomain of FGFR2b harboring P253R Apert mutation 2010-08-23 2011-08-31 Beenken, A.,Eliseenkova, A.V.,Ibrahimi, O.A.,Olsen, S.K.,Mohammadi, M. Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem. 2012 287 3067 3078 3P5Y 23030629 Crystal structure of the mutant T159A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-10-11 2011-09-21 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3P5Z 23030629 Crystal structure of the mutant T159S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-10-11 2011-09-21 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3P60 23030629 Crystal structure of the mutant T159V of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-10-11 2011-09-21 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3P61 23030629 Crystal structure of the mutant R160A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 2010-10-11 2011-09-21 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3PBU 21870810 Crystal structure of the mutant I96S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-10-21 2011-09-21 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3PBV 21870810 Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-10-21 2011-09-21 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3PBW 21870810 Crystal structure of the mutant L123N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-10-21 2011-09-21 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3PBY 21870810 Crystal structure of the mutant L123S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-10-21 2011-09-21 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3PC0 21870810 Crystal structure of the mutant V155S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2010-10-21 2011-09-21 Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry 2011 50 8497 8507 3SY5 Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP 2011-07-15 2011-09-21 Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Iiams, V.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP To be Published 0 0 0 0 3OW1 Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens complexed with MG 2010-09-17 2011-09-28 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF D-MANNONATE DEHYDRATASE FROM CHROMOHALOBACTER SALEXIGENS complexed with MG To be Published 0 0 0 0 3OZM Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg, m-Xylarate and L-Lyxarate 2010-09-25 2011-09-28 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg, m-Xylarate and L-Lyxarate TO BE PUBLISHED 0 0 0 0 3OZY Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg and m-Xylarate 2010-09-27 2011-09-28 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg and m-Xylarate To be Published 0 0 0 0 3P78 22014550 P38 inhibitor-bound 2010-10-12 2011-10-12 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3P79 22014550 P38 inhibitor-bound 2010-10-12 2011-10-12 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3P7A 22014550 p38 inhibitor-bound 2010-10-12 2011-10-12 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3P7B 22014550 p38 inhibitor-bound 2010-10-12 2011-10-12 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3P7C 22014550 p38 inhibitor-bound 2010-10-12 2011-10-12 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3U07 Crystal Structure of the VPA0106 protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium Target VpR106. 2011-09-28 2011-10-12 Vorobiev, S.,Neely, H.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the VPA0106 protein from Vibrio parahaemolyticus. To be Published 0 0 0 0 3P93 Crystal structure of D-mannonate dehydratase from Chromohalobacter Salexigens complexed with MG,D-Mannonate and 2-keto-3-deoxy-D-Gluconate 2010-10-15 2011-10-19 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF D-MANNONATE DEHYDRATASE FROM CHROMOHALOBACTER SALEXIGENS complexed with MG,D-Mannonate and 2-keto-3-deoxy-D-Gluconate To be Published 0 0 0 0 3U4T Crystal Structure of the C-terminal part of the TPR repeat-containing protein Q11TI6_CYTH3 from Cytophaga hutchinsonii. Northeast Structural Genomics Consortium Target ChR11B. 2011-10-10 2011-10-19 Vorobiev, S.,Neely, H.,Chen, Y.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Maglaqui, M.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the C-terminal part of the TPR repeat-containing protein Q11TI6_CYTH3 from Cytophaga hutchinsonii. To be Published 0 0 0 0 3TUV 22049080 Crystal structure of insulysin with bound ATP 2011-09-19 2011-10-26 Noinaj, N.,Song, E.S.,Bhasin, S.,Alper, B.J.,Schmidt, W.K.,Hersh, L.B.,Rodgers, D.W. Anion Activation Site of Insulin-degrading Enzyme. J.Biol.Chem. 2012 287 48 57 3P5K 22014550 P38 inhibitor-bound 2010-10-08 2011-11-02 Moffett, K.,Konteatis, Z.,Nguyen, D.,Shetty, R.,Ludington, J.,Fujimoto, T.,Lee, K.J.,Chai, X.,Namboodiri, H.,Karpusas, M.,Dorsey, B.,Guarnieri, F.,Bukhtiyarova, M.,Springman, E.,Michelotti, E. Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD). Bioorg.Med.Chem.Lett. 2011 21 7155 7165 3PFR Crystal structure of D-Glucarate dehydratase related protein from Actinobacillus Succinogenes complexed with D-Glucarate 2010-10-29 2011-11-02 Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.,Ghasempur, S.,Gerlt, J.A.,Almo, S.C. Crystal structure of D-Glucarate dehydratase related protein from Actinobacillus Succinogenes complexed with D-Glucarate To be Published 0 0 0 0 3TBD 22041449 Crystal Structure of domain VI and LE1 of human Netrin-G2 2011-08-05 2011-11-02 Brasch, J.,Harrison, O.J.,Ahlsen, G.,Liu, Q.,Shapiro, L. Crystal structure of the ligand binding domain of netrin g2. J.Mol.Biol. 2011 414 723 734 3THT 22065580 Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B 2011-08-19 2011-11-02 Pastore, C.,Topalidou, I.,Forouhar, F.,Yan, A.C.,Levy, M.,Hunt, J.F. Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. J.Biol.Chem. 2012 287 2130 2143 3U02 Crystal Structure of the tRNA modifier TiaS from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR225 2011-09-28 2011-11-02 Kuzin, A.,Lew, S.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the tRNA modifier TiaS from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR225 To be Published 0 0 0 0 3TX3 CysZ, a putative sulfate permease 2011-09-22 2011-11-09 Assur, Z.,Liu, Q.,Hendrickson, W.A.,Mancia, F. CysZ, a putative sulfate permease To be Published 0 0 0 0 3PK7 Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens with MG and Glycerol bound in the active site 2010-11-11 2011-11-16 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens with MG and Glycerol bound in the active site To be Published 0 0 0 0 3PNZ Crystal structure of the lactonase Lmo2620 from Listeria monocytogenes 2010-11-20 2011-11-23 Fedorov, A.A.,Fedorov, E.V.,Xiang, D.F.,Raushel, F.M.,Almo, S.C. Crystal structure of the lactonase Lmo2620 from Listeria monocytogenes To be Published 0 0 0 0 3U26 23330600 Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR48 2011-09-30 2011-11-23 Bjelic, S.,Nivon, L.G.,Celebi-Olcum, N.,Kiss, G.,Rosewall, C.F.,Lovick, H.M.,Ingalls, E.L.,Gallaher, J.L.,Seetharaman, J.,Lew, S.,Montelione, G.T.,Hunt, J.F.,Michael, F.E.,Houk, K.N.,Baker, D. Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction. Acs Chem.Biol. 2013 8 749 757 3UF1 22740688 Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B 2011-10-31 2011-11-30 Aziz, A.,Hess, J.F.,Budamagunta, M.S.,Voss, J.C.,Kuzin, A.P.,Huang, Y.J.,Xiao, R.,Montelione, G.T.,FitzGerald, P.G.,Hunt, J.F. The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography. J.Biol.Chem. 2012 287 28349 28361 3U1V 22871159 X-ray Structure of De Novo design cysteine esterase FR29, Northeast Structural Genomics Consortium Target OR52 2011-09-30 2011-12-07 Richter, F.,Blomberg, R.,Khare, S.D.,Kiss, G.,Kuzin, A.P.,Smith, A.J.,Gallaher, J.,Pianowski, Z.,Helgeson, R.C.,Grjasnow, A.,Xiao, R.,Seetharaman, J.,Su, M.,Vorobiev, S.,Lew, S.,Forouhar, F.,Kornhaber, G.J.,Hunt, J.F.,Montelione, G.T.,Tong, L.,Houk, K.N.,Hilvert, D.,Baker, D. Computational design of catalytic dyads and oxyanion holes for ester hydrolysis. J.Am.Chem.Soc. 2012 134 16197 16206 3OJV 22057274 Crystal Structure of FGF1 complexed with the ectodomain of FGFR1c exhibiting an ordered ligand specificity-determining betaC'-betaE loop 2010-08-23 2011-12-28 Beenken, A.,Eliseenkova, A.V.,Ibrahimi, O.A.,Olsen, S.K.,Mohammadi, M. Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem. 2012 287 3067 3078 3PWG Crystal structure of the mutant S29G.P34A of D-Glucarate dehydratase from Escherichia coli complexed with product 5-keto-4-deoxy-D-Glucarate 2010-12-08 2011-12-28 Fedorov, A.A.,Fedorov, E.V.,Lukk, T.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant S29G.P34A of D-Glucarate dehydratase from Escherichia Coli complexed with product 5-keto-4-deoxy-D-Glucarate To be Published 0 0 0 0 3PWI Crystal structure of the mutant P34A of D-Glucarate dehydratase from Escherichia coli complexed with product 5-keto-4-deoxy-D-Glucarate 2010-12-08 2011-12-28 Fedorov, A.A.,Fedorov, E.V.,Lukk, T.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant P34A of D-Glucarate dehydratase from Escherichia Coli complexed with product 5-keto-4-deoxy-D-Glucarate To be Published 0 0 0 0 3QEZ 23030629 Crystal structure of the mutant T159V,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-01-20 2012-01-25 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3QF0 23030629 Crystal structure of the mutant T159V,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-01-20 2012-01-25 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3VK6 22252131 Crystal structure of a phosphotyrosine binding domain 2011-11-09 2012-01-25 Mukherjee, M.,Chow, S.Y.,Yusoff, P.,Seetharaman, J.,Ng, C.,Sinniah, S.,Koh, X.W.,Asgar, N.F.,Li, D.,Yim, D.,Jackson, R.A.,Yew, J.,Qian, J.,Iyu, A.,Lim, Y.P.,Zhou, X.,Sze, S.K.,Guy, G.R.,Sivaraman, J. Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin Embo J. 2012 31 1308 1319 3QKE Crystal structure of D-mannonate dehydratase from Chromohalobacter Salexigens complexed with Mg and D-Gluconate 2011-02-01 2012-02-01 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Cystal structure of D-mannonate dehydratase from Chromohalobacter salexigens complexed with Mg and D-Gluconate To be Published 0 0 0 0 3QMR 23030629 Crystal structure of the mutant R160A,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-02-05 2012-02-08 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3QMS 23030629 Crystal structure of the mutant T159V,V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-02-05 2012-02-08 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3QMT 23030629 Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-02-05 2012-02-08 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3UW6 23330600 Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR120 2011-11-30 2012-02-08 Bjelic, S.,Nivon, L.G.,Celebi-Olcum, N.,Kiss, G.,Rosewall, C.F.,Lovick, H.M.,Ingalls, E.L.,Gallaher, J.L.,Seetharaman, J.,Lew, S.,Montelione, G.T.,Hunt, J.F.,Michael, F.E.,Houk, K.N.,Baker, D. Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction. Acs Chem.Biol. 2013 8 749 757 3QPE Crystal structure of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with D-Galacturonate and 5-keto-4-deoxy-D-Galacturonate 2011-02-12 2012-02-15 Fedorov, A.A.,Fedorov, E.V.,Mills-Groninger, F.,Gerlt, J.A.,Almo, S.C. Crystal structure of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with D-Galacturonate and 5-keto-4-deoxy-D-Galacturonate To be Published 0 0 0 0 4DLH Crystal Structure of the protein Q9HRE7 from Halobacterium salinarium at the resolution 1.9A, Northeast Structural Genomics Consortium (NESG) Target HsR50 2012-02-06 2012-02-15 Kuzin, A.,Chen, Y.,Seetharaman, J.,Mao, M.,Xiao, R.,Ciccosanti, C.,Zhao, L.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target HsR50 To be Published 0 0 0 0 3R0D Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site 2011-03-07 2012-03-07 Fedorov, A.A.,Fedorov, E.V.,Kamat, S.,Hitchcock, D.,Raushel, F.M.,Almo, S.C. Crystal structure of Cytosine Deaminase from Escherichia Coli complexed with two zinc atoms in the active site To be Published 0 0 0 0 3R25 Crystal structure of enolase superfamily member from Vibrionales bacterium complexed with Mg and Glycerol in the active site 2011-03-13 2012-03-14 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of enolase superfamily member from VIBRIONALES BACTERIUM complexed with Mg and Glycerol in the active site To be Published 0 0 0 0 3RGT Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with D-Arabinohydroxamate 2011-04-09 2012-04-11 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with d-arabinohydroxamate To be Published 0 0 0 0 4DRT 24705591 Three dimensional structure of de novo designed serine hydrolase OSH26, Northeast Structural Genomics Consortium (NESG) target OR89 2012-02-17 2012-04-18 Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol. 2014 10 386 391 3RLU 23030629 Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-04-20 2012-04-25 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 3RLV 23030629 Crystal structure of the mutant Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 2011-04-20 2012-04-25 Desai, B.J.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Goryanova, B.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry 2012 51 8665 8678 4E0A Crystal Structure of the mutant F44R BH1408 protein from Bacillus halodurans, Northeast Structural Genomics Consortium (NESG) Target BhR182 2012-03-02 2012-05-02 Kuzin, A.,Neely, H.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target BhR182 To be Published 0 0 0 0 3S47 Crystal structure of enolase superfamily member from Clostridium beijerincki complexed with Mg 2011-05-18 2012-05-23 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of enolase superfamily member from Clostridium beijerincki complexed with Mg To be Published 0 0 0 0 3VB9 Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 2011-12-31 2012-05-23 Seetharaman, J.,Neely, H.,Cunningham, K.,Ciccosanti, C.,Bjelic, S.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 To be Published 0 0 0 0 3STO 22683791 Serpin from the trematode Schistosoma Haematobium 2011-07-11 2012-05-30 Granzin, J.,Huang, Y.,Topbas, C.,Huang, W.,Wu, Z.,Misra, S.,Hazen, S.L.,Blanton, R.E.,Lee, X.,Weiergraber, O.H. Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D 2012 68 686 694 3STO 22683791 Serpin from the trematode Schistosoma Haematobium 2011-07-11 2012-05-30 Granzin, J.,Huang, Y.,Topbas, C.,Huang, W.,Wu, Z.,Misra, S.,Hazen, S.L.,Blanton, R.E.,Lee, X.,Weiergraber, O.H. Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D 2012 68 686 694 4F67 Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target LgR82 2012-05-14 2012-05-30 Kuzin, A.,Neely, H.,Street, L.,Odukwe, N.,Seetharaman, J.,Mao, M.,Xiao, R.,Kohan, E.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target LgR82 To be Published 0 0 0 0 3SBF Crystal structure of the mutant P311A of enolase superfamily member from VIBRIONALES BACTERIUM complexed with Mg and D-Arabinonate 2011-06-04 2012-06-06 Fedorov, A.A.,Fedorov, E.V.,Wichelecki, D.,Gerlt, J.A.,Almo, S.C. Crystal structure of the mutant P311A of enolase superfamily member from Vibrionales bacterium complexed with Mg and D-Arabinonate To be Published 0 0 0 0 3VA9 Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain 2011-12-29 2012-06-06 Zhang, Z.,Liu, Q.,Hendrickson, W.A. Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain To be Published 0 0 0 0 3VB8 23827138 Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43 2011-12-31 2012-06-06 Procko, E.,Hedman, R.,Hamilton, K.,Seetharaman, J.,Fleishman, S.J.,Su, M.,Aramini, J.,Kornhaber, G.,Hunt, J.F.,Tong, L.,Montelione, G.T.,Baker, D. Computational design of a protein-based enzyme inhibitor. J.Mol.Biol. 2013 425 3563 3575 4F9K Crystal Structure of human cAMP-dependent protein kinase type I-beta regulatory subunit (fragment 11-73), Northeast Structural Genomics Consortium (NESG) Target HR8613A 2012-05-18 2012-06-06 Kuzin, A.,Lew, S.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Shastry, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Crystal Structure of human cAMP-dependent protein kinase type I-beta regulatory subunit (fragment 11-73), Northeast Structural Genomics Consortium (NESG) Target HR8613A To be Published 0 0 0 0 3VA6 Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron 2011-12-28 2012-06-13 Zhang, Z.,Liu, Q.,Hendrickson, W.A. The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont To be Published 0 0 0 0 4ESS 24705591 Crystal Structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium (NESG) Target OR187 2012-04-23 2012-06-13 Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol. 2014 10 386 391 4FIB Crystal structure of the ydhK protein from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR518A. 2012-06-08 2012-06-20 Vorobiev, S.,Abashidze, M.,Seetharaman, J.,Mao, M.,Xiao, R.,Maglaqui, M.,Owens, L.A.,Cunningham, K.,Zhao, L.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of the ydhK protein from Bacillus subtilis. To be Published 0 0 0 0 4DMG 22711535 Thermus thermophilus m5C1942 methyltransferase RlmO 2012-02-07 2012-06-27 Larsen, L.H.,Rasmussen, A.,Giessing, A.M.,Jogl, G.,Kirpekar, F. Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m5C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942. J.Biol.Chem. 2012 287 27593 27600 4ETO Structure of S100A4 in complex with non-muscle myosin-IIA peptide 2012-04-24 2012-07-11 Ramagopal, U.A.,Dulyaninova, N.G.,Kumar, P.R.,Almo, S.C.,Bresnick, A.R. Structure of S100A4 with bound peptide P To be Published 0 0 0 0 4FEK Crystal Structure of putative diflavin flavoprotein A 5 (fragment 1-254) from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR435A , Northeast Structural Genomics Consortium (NESG) Target NsR435A 2012-05-30 2012-07-11 Kuzin, A.,Abashidze, M.,Seetharaman, J.,Janjua, J.,Xiao, R.,Foote, E.L.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target NsR435A To be Published 0 0 0 0 3SWB 23633581 Crystal structure of the amino-terminal domain of human cardiac troponin C in complex with cadmium at 1.7 A resolution 2011-07-13 2012-07-18 Zhang, X.L.,Tibbits, G.F.,Paetzel, M. The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D 2013 69 722 734 4FLE Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 2012-06-14 2012-08-08 Forouhar, F.,Lew, S.,Seetharaman, J.,Shastry, R.,Kohan, E.,Maglaqui, M.,Mao, L.,Xiao, R.,Acton, T.B.,Everett, J.K.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 (CASP Target) To be Published 0 0 0 0 4FJ4 Crystal structure of the protein Q9HRE7 complexed with mercury from Halobacterium salinarium at the resolution 2.1A, Northeast Structural Genomics Consortium target HsR50 2012-06-11 2012-08-22 Kuzin, A.,Chen, Y.,Vorobiev, S.M.,Seetharaman, J.,Janjua, J.,Xiao, R.,Cunningham, K.,Maglaqui, M.,Owens, L.A.,Wang, H.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target HsR50 To be Published 0 0 0 0 4GMR 28338692 Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR266. 2012-08-16 2012-08-29 Fallas, J.A.,Ueda, G.,Sheffler, W.,Nguyen, V.,McNamara, D.E.,Sankaran, B.,Pereira, J.H.,Parmeggiani, F.,Brunette, T.J.,Cascio, D.,Yeates, T.R.,Zwart, P.,Baker, D. Computational design of self-assembling cyclic protein homo-oligomers. NAT.CHEM. 2017 9 353 360 4GVV Crystal Structure of de novo design serine hydrolase OSH55.27, Northeast Structural Genomics Consortium (NESG) Target OR246 2012-08-31 2012-09-12 Kuzin, A.,Lew, S.,Seetharaman, J.,Mao, M.,Xiao, R.,Kohan, E.,Rajagopalan, S.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target OR246 To be Published 0 0 0 0 3TCA 23045549 Crystal structure of the Ras-associating and pleckstrin-homology domains of RIAM 2011-08-08 2012-09-26 Wynne, J.P.,Wu, J.,Su, W.,Mor, A.,Patsoukis, N.,Boussiotis, V.A.,Hubbard, S.R.,Philips, M.R. Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector. J.Cell Biol. 2012 199 317 329 4H9D Crystal Structure of Mn-dependent Gme HNH nicking endonuclease from Geobacter metallireducens GS-15, Northeast Structural Genomics Consortium (NESG) Target GmR87 2012-09-24 2012-10-10 Kuzin, A.,Chen, Y.,Seetharaman, J.,Fang, F.,Xiao, R.,Cunningham, K.,Ma, L.,Owens, L.,Chen, C.X.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target GmR87 To be Published 0 0 0 0 4F35 23086149 Crystal Structure of a bacterial dicarboxylate/sodium symporter 2012-05-08 2012-10-24 Mancusso, R.,Gregorio, G.G.,Liu, Q.,Wang, D.N. Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter. Nature 2012 491 622 626 4HCH CRYSTAL STRUCTURE OF D-GLUCARATE DEHYDRATASE FROM AGROBACTERIUM TUMEFACIENS complexed with magnesium and L-tartrate 2012-09-29 2012-10-24 Fedorov, A.A.,Fedorov, E.V.,Sakai, A.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF D-GLUCARATE DEHYDRATASE FROM AGROBACTERIUM TUMEFACIENS complexed with magnesium and L-tartrate To be Published 0 0 0 0 4HCL CRYSTAL STRUCTURE OF D-GLUCARATE DEHYDRATASE FROM AGROBACTERIUM TUMEFACIENS complexed with magnesium and L-Lyxarohydroxamate 2012-09-30 2012-10-24 Fedorov, A.A.,Fedorov, E.V.,Sakai, A.,Gerlt, J.A.,Almo, S.C. CRYSTAL STRUCTURE OF D-GLUCARATE DEHYDRATASE FROM AGROBACTERIUM TUMEFACIENS complexed with magnesium and L-Lyxarohydroxamate To be Published 0 0 0 0 4HQD Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR265. 2012-10-25 2012-11-14 Vorobiev, S.,Su, M.,Parmeggiani, F.,Seetharaman, J.,Huang, P.-S.,Maglaqui, M.,Xiao, R.,Lee, D.,Everett, J.K.,Acton, T.B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of Engineered Protein OR265. To be Published 0 0 0 0 4HXT 28338692 Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR329 2012-11-12 2012-11-21 Fallas, J.A.,Ueda, G.,Sheffler, W.,Nguyen, V.,McNamara, D.E.,Sankaran, B.,Pereira, J.H.,Parmeggiani, F.,Brunette, T.J.,Cascio, D.,Yeates, T.R.,Zwart, P.,Baker, D. Computational design of self-assembling cyclic protein homo-oligomers. NAT.CHEM. 2017 9 353 360 4G3U 23184707 Mycobacterium smegmatis DprE1 - monoclinic crystal form 2012-07-15 2012-12-05 Li, H.,Jogl, G. Crystal structure of decaprenylphosphoryl-beta- D-ribose 2'-epimerase from Mycobacterium smegmatis. Proteins 2013 81 538 543 4FPW 25079510 Crystal Structure of CalU16 from Micromonospora echinospora. Northeast Structural Genomics Consortium Target MiR12. 2012-06-22 2012-12-12 Elshahawi, S.I.,Ramelot, T.A.,Seetharaman, J.,Chen, J.,Singh, S.,Yang, Y.,Pederson, K.,Kharel, M.K.,Xiao, R.,Lew, S.,Yennamalli, R.M.,Miller, M.D.,Wang, F.,Tong, L.,Montelione, G.T.,Kennedy, M.A.,Bingman, C.A.,Zhu, H.,Phillips, G.N.,Thorson, J.S. Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19. Acs Chem.Biol. 2014 9 2347 2358 4HFX Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. 2012-10-05 2012-12-12 Seetharaman, J.,Su, M.,Ciccosanti, C.,Sahdev, S.,Acton, T.B.,Xiao, R.,K Everett, J.,T Montelione, G.,Hunt, J.F.,Tong, L. Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. (CASP Target) TO BE PUBLISHED 0 0 0 0 4HG0 Crystal Structure of magnesium and cobalt efflux protein CorC, Northeast Structural Genomics Consortium (NESG) Target ER40 2012-10-05 2013-02-06 Kuzin, A.,Neely, H.,Seetharaman, J.,Patel, P.,Xiao, R.,Ciccosanti, C.,Cooper, B.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target ER40 To be Published 0 0 0 0 4FFD Crystal structure of engineered protein. northeast structural genomics consortium target or48 2012-05-31 2013-02-13 Seetharaman, J.,Lew, S.,Nivon, L.,Baker, D.,Bjelic, S.,Ciccosanti, C.,Sahdev, S.,Xiao, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of engineered protein. northeast structural genomics consortium target or48 To be Published 0 0 0 0 4ILS Crystal structure of engineered protein. northeast structural genomics Consortium target or117 2012-12-31 2013-03-20 Seetharaman, J.,Lew, S.,Nivon, L.,Baker, D.,Bjelic, S.,Ciccosanti, C.,Sahdev, S.,Xiao, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal structure of engineered protein. northeast structural genomics Consortium target or117 To be Published 0 0 0 0 4JCA 24705591 Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273 2013-02-21 2013-03-20 Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol. 2014 10 386 391 4JGK Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 2013-03-01 2013-03-20 Kuzin, A.,Lew, S.,Rajagopalan, S.,Seetharaman, J.,Mao, L.,Xiao, R.,Lee, D.,Everett, J.K.,Acton, T.B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 To be Published 0 0 0 0 4JLL 24705591 Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273 2013-03-12 2013-04-10 Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol. 2014 10 386 391 3U91 Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein 2011-10-17 2013-04-24 Liu, J.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M. Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein To be Published 0 0 0 0 4JVV 24705591 Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273 2013-03-26 2013-04-24 Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol. 2014 10 386 391 4K0C Crystal Structure of the computationally designed serine hydrolase. Northeast Structural Genomics Consortium (NESG) Target OR317 2013-04-03 2013-04-24 Kuzin, A.,Lew, S.,Rajagopalan, S.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Lee, D.,Everett, J.K.,Acton, T.B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F. Northeast Structural Genomics Consortium Target OR317 To be Published 0 0 0 0 3UIA Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein 2011-11-04 2013-05-08 Liu, J.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M. Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein To be Published 0 0 0 0 4JXI Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184 2013-03-28 2013-05-22 Kuzin, A.,Smith, M.D.,Richter, F.,Lew, S.,Seetharaman, R.,Bryan, C.,Lech, Z.,Kiss, G.,Moretti, R.,Maglaqui, M.,Xiao, R.,Kohan, E.,Smith, M.,Everett, J.K.,Nguyen, R.,Pande, V.,Hilvert, D.,Kornhaber, G.,Baker, D.,Montelione, G.T.,Hunt, J.F.,Tong, L. Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184 To be Published 0 0 0 0 4JN4 23708608 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 2013-03-14 2013-05-29 Qi, R.,Sarbeng, E.B.,Liu, Q.,Le, K.Q.,Xu, X.,Xu, H.,Yang, J.,Wong, J.L.,Vorvis, C.,Hendrickson, W.A.,Zhou, L.,Liu, Q. Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol. 2013 20 900 907 4KAA Crystal structure of the halotag2 protein at the resolution 2.3A, Northeast Structural Genomics Consortium (NESG) target OR150 2013-04-22 2013-06-05 Kuzin, A.,Lew, S.,Neklesa, T.K.,Noblin, D.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Wang, H.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Crews, C.,Tong, L. Northeast Structural Genomics Consortium Target OR150 To be Published 0 0 0 0 4KAC X-Ray Structure of the complex HaloTag2 with HALTS. Northeast Structural Genomics Consortium (NESG) Target OR150. 2013-04-22 2013-06-05 Kuzin, A.,Lew, S.,Neklesa, T.K.,Noblin, D.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Wang, H.,Everett, J.K.,Acton, T.B.,Kornhaber, G.,Montelione, G.T.,Crews, C.M.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target OR150 To be Published 0 0 0 0 4KAF Crystal Structure of Haloalkane dehalogenase HaloTag7 at the resolution 1.5A, Northeast Structural Genomics Consortium (NESG) Target OR151 2013-04-22 2013-06-05 Kuzin, A.P.,Lew, S.,Neklesa, T.K.,Noblin, D.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Wang, H.,Everett, J.K.,Acton, T.B.,Kornhaber, G.,Montelione, G.T.,Crews, C.,Tong, L. Northeast Structural Genomics Consortium Target OR151 To be Published 0 0 0 0 4KAJ X-Ray Structure of the complex of Haloalkane dehalogenase HaloTag7 with HALTS, Northeast Structural Genomics Consortium (NESG) Target OR151 2013-04-22 2013-06-05 Kuzin, A.,Lew, S.,Neklesa, T.K.,Noblin, D.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Wang, H.,Everett, J.K.,Acton, T.B.,Kornhaber, G.,Montelione, G.T.,Crews, C.M.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target OR151 To be Published 0 0 0 0 4KY3 26650357 Three-dimensional Structure of the orthorhombic crystal of computationally designed insertion domain , Northeast Structural Genomics Consortium (NESG) Target OR327 2013-05-28 2013-06-19 King, I.C.,Gleixner, J.,Doyle, L.,Kuzin, A.,Hunt, J.F.,Xiao, R.,Montelione, G.T.,Stoddard, B.L.,DiMaio, F.,Baker, D. Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife 2015 4 0 0 4L7W Crystal structure mutant H77A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 2013-06-14 2013-07-03 Kuzin, A.,Su, M.,Yakunin, A.,Beloglazova, N.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Lee, D.,Brown, G.,Flick, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Northeast Structural Genomics Consortium Target HR6723 To be Published 0 0 0 0 4KYV Crystal Structure of dehalogenase HaloTag2 with HALTS at the resolution 1.8A. Northeast Structural Genomics Consortium (NESG) Target OR150 2013-05-29 2013-07-24 Kuzin, A.,Lew, S.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Wang, H.,Everett, J.K.,Acton, T.B.,Kornhaber, G.,Montelione, G.T.,Hunt, J.F.,Tong, L. Northeast Structural Genomics Consortium Target OR150 To be Published 0 0 0 0 4L7E Three dimensional structure of mutant D78A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 2013-06-13 2013-07-24 Kuzin, A.,Su, M.,Yakunin, A.,Beloglazova, N.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Lee, D.,Brown, G.,Flick, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Northeast Structural Genomics Consortium Target HR6723 To be Published 0 0 0 0 4J95 23871672 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome in Space Group C2. 2013-02-15 2013-08-07 Chen, H.,Huang, Z.,Dutta, K.,Blais, S.,Neubert, T.A.,Li, X.,Cowburn, D.,Traaseth, N.J.,Mohammadi, M. Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep 2013 4 376 384 4J97 23871672 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659E Mutation Identified in Endometrial Cancer. 2013-02-15 2013-08-07 Chen, H.,Huang, Z.,Dutta, K.,Blais, S.,Neubert, T.A.,Li, X.,Cowburn, D.,Traaseth, N.J.,Mohammadi, M. Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep 2013 4 376 384 4J98 23871672 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Gain-of-Function K659Q Mutation. 2013-02-15 2013-08-07 Chen, H.,Huang, Z.,Dutta, K.,Blais, S.,Neubert, T.A.,Li, X.,Cowburn, D.,Traaseth, N.J.,Mohammadi, M. Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep 2013 4 376 384 4J99 23871672 Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Gain-of-Function K659T Mutation. 2013-02-15 2013-08-07 Chen, H.,Huang, Z.,Dutta, K.,Blais, S.,Neubert, T.A.,Li, X.,Cowburn, D.,Traaseth, N.J.,Mohammadi, M. Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep 2013 4 376 384 4GF8 Crystal Structure of the Chitin Oligasaccharide Binding Protein 2012-08-03 2013-08-21 Xu, S.,Li, X.,Gu, L.,Roseman, R.,Stock, A.M. Chitin catabolic cascade in the marine bacterium Vibrio cholerae: properties, structure and functions of a periplasmic chitooligosaccharide binding protein (CBP) To be Published 0 0 0 0 4L0R Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A. 2013-05-31 2013-09-04 Seetharaman, J.,Lew, S.,Su, M.,Ciccosanti, C.,Sahdev, S.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics consortium id HR9027A To be Published 0 0 0 0 4MO1 Crystal structure of antitermination protein Q from bacteriophage lambda. Northeast Structural Genomics Consortium target OR18A. 2013-09-11 2013-09-25 Vorobiev, S.,Su, M.,Nickels, B.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Kogan, S.,Maglaqui, M.,Wang, D.,Everett, J.K.,Acton, T.B.,Ebright, R.H.,Montelione, G.T.,Hunt, J.,Tong, L. Crystal structure of antitermination protein Q from bacteriophage lambda. To be Published 0 0 0 0 4MPS 24155237 Crystal structure of rat Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), Northeast Structural Genomics Consortium Target RnR367A 2013-09-13 2013-09-25 Meng, L.,Forouhar, F.,Thieker, D.,Gao, Z.,Ramiah, A.,Moniz, H.,Xiang, Y.,Seetharaman, J.,Milaninia, S.,Su, M.,Bridger, R.,Veillon, L.,Azadi, P.,Kornhaber, G.,Wells, L.,Montelione, G.T.,Woods, R.J.,Tong, L.,Moremen, K.W. Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION. J.Biol.Chem. 2013 288 34680 34698 4KD7 24053334 Human dihydrofolate reductase complexed with NADPH and 5-{3-[3-methoxy-5(pyridine-4-yl)phenyl]prop-1-yn-1-yl}-6-ethyl-pyrimidine-2,4-diamine 2013-04-24 2013-10-09 Lamb, K.M.,G-Dayanandan, N.,Wright, D.L.,Anderson, A.C. Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase. Biochemistry 2013 52 7318 7326 4KEB 24053334 Human dihydrofolate reductase complexed with NADPH and 5-{3-[3-methoxy-5-(isoquin-5-yl)phenyl]but-1-yn-1-yl}6-ethylpyrimidine-2,4-diamine 2013-04-25 2013-10-09 Lamb, K.M.,G-Dayanandan, N.,Wright, D.L.,Anderson, A.C. Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase. Biochemistry 2013 52 7318 7326 4KFJ 24053334 Human dihydrofolate reductase complexed with NADPH and 5-{3-[3-methoxy-5-(isoquin-5-yl)phenyl]prop-1-yn-1-yl}6-ethylprimidine-2,4-diamine 2013-04-26 2013-10-09 Lamb, K.M.,G-Dayanandan, N.,Wright, D.L.,Anderson, A.C. Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase. Biochemistry 2013 52 7318 7326 4N7T Crystal structure of phosphorylated phosphopentomutase from streptococcus mutans 2013-10-16 2013-11-06 Fedorov, A.A.,Fedorov, E.V.,Bonanno, J.,Burley, S.K.,Almo, S.C. Crystal structure of phosphorylated phosphopentomutase from streptococcus mutans To be Published 0 0 0 0 4N3P Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 2013-10-07 2013-11-13 Kuzin, A.,Lew, S.,Rajagopalan, S.,Seetharaman, J.,Mao, L.,Xiao, R.,Kogan, S.,Maglaqui, M.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 To be Published 0 0 0 0 4N9X Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 2013-10-21 2013-11-20 Kuzin, A.,Chen, Y.,Lew, S.,Seetharaman, J.,Mao, L.,Xiao, R.,Owens, L.A.,Wang, D.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 To be Published 0 0 0 0 4NUW Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate 2013-12-04 2013-12-18 Fedorov, A.A.,Fedorov, E.V.,Chan, K.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate To be Published 0 0 0 0 4NVS Crystal Structure of the Q18CP6_CLOD6 protein from glyoxalase family. Northeast Structural Genomics Consortium Target CfR3 2013-12-05 2013-12-18 Vorobiev, S.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Ciccosanti, C.,Wang, H.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Q18CP6_CLOD6 protein from glyoxalase family. To be Published 0 0 0 0 4NX5 Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 2013-12-08 2013-12-25 Fedorov, A.A.,Fedorov, E.V.,Chan, K.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate To be Published 0 0 0 0 4O11 Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-hydroxyuridine 5'-monophosphate 2013-12-14 2014-01-15 Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-hydroxyuridine 5'-monophosphate To be Published 0 0 0 0 4O8R Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate 2013-12-29 2014-01-22 Fedorov, A.A.,Fedorov, E.V.,Chan, K.K.,Gerlt, J.A.,Almo, S.C. Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate To be Published 0 0 0 0 4MO7 24385909 Crystal structure of superantigen PfiT 2013-09-11 2014-02-05 Liu, L.,Chen, H.,Brecher, M.B.,Li, Z.,Wei, B.,Nandi, B.,Zhang, J.,Ling, H.,Winslow, G.,Braun, J.,Li, H. Pfit is a structurally novel Crohn's disease-associated superantigen. Plos Pathog. 2013 9 0 0 4HOE 24568657 Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E) 2012-10-22 2014-03-19 G-Dayanandan, N.,Paulsen, J.L.,Viswanathan, K.,Keshipeddy, S.,Lombardo, M.N.,Zhou, W.,Lamb, K.M.,Sochia, A.E.,Alverson, J.B.,Priestley, N.D.,Wright, D.L.,Anderson, A.C. Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J.Med.Chem. 2014 57 2643 2656 4HOF 24568657 Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H) 2012-10-22 2014-03-19 G-Dayanandan, N.,Paulsen, J.L.,Viswanathan, K.,Keshipeddy, S.,Lombardo, M.N.,Zhou, W.,Lamb, K.M.,Sochia, A.E.,Alverson, J.B.,Priestley, N.D.,Wright, D.L.,Anderson, A.C. Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J.Med.Chem. 2014 57 2643 2656 4PSJ Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR464. 2014-03-07 2014-03-26 Vorobiev, S.,Parmeggiani, F.,Seetharaman, J.,Huang, P.-S.,Janjua, H.,Xiao, R.,Maglaqui, M.,Park, K.,Everett, J.K.,Acton, T.B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J. Crystal Structure of Engineered Protein OR464. To be Published 0 0 0 0 4PAS 24778228 Heterodimeric coiled-coil structure of human GABA(B) receptor 2014-04-10 2014-05-07 Burmakina, S.,Geng, Y.,Chen, Y.,Fan, Q.R. Heterodimeric coiled-coil interactions of human GABAB receptor. Proc.Natl.Acad.Sci.USA 2014 111 6958 6963 4PGW 24904158 Crystal structure of YetJ from Bacillus Subtilis at pH 6 by Pt-SAD 2014-05-02 2014-06-04 Chang, Y.,Bruni, R.,Kloss, B.,Assur, Z.,Kloppmann, E.,Rost, B.,Hendrickson, W.A.,Liu, Q. Structural basis for a pH-sensitive calcium leak across membranes. Science 2014 344 1131 1135 4TKQ 25286840 Native-SAD phasing for YetJ from Bacillus Subtilis 2014-05-27 2014-06-18 Liu, Q.,Guo, Y.,Chang, Y.,Cai, Z.,Assur, Z.,Mancia, F.,Greene, M.I.,Hendrickson, W.A. Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D 2014 70 2544 2557 4TKR 25286840 Native-SAD phasing for ThiT from Listeria monocytogenes serovar. 2014-05-27 2014-06-18 Liu, Q.,Guo, Y.,Chang, Y.,Cai, Z.,Assur, Z.,Mancia, F.,Greene, M.I.,Hendrickson, W.A. Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D 2014 70 2544 2557 4PY9 Crystal structure of an exopolyphosphatase-related protein from Bacteroides Fragilis. Northeast Structural Genomics target BFR192 2014-03-26 2014-06-25 Seetharaman, J.,Abashidze, M.,Wang, H.,Janjua, H.,Foote, E.L.,Xiao, R.,Nair, R.,Everett, J.K.,Acton, T.B.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) Crystal structure of an exopolyphosphatase-related protein from Bacteroides Fragilis. Northeast Structural Genomics target BFR192 To be Published 0 0 0 0 4MXM 24385909 Crystal structure of superantigen pfit 2013-09-26 2014-09-17 Liu, L.,Chen, H.,Brecher, M.B.,Li, Z.,Wei, B.,Nandi, B.,Zhang, J.,Ling, H.,Winslow, G.,Braun, J.,Li, H. Pfit is a structurally novel Crohn's disease-associated superantigen. Plos Pathog. 2013 9 0 0 4U9A 25201411 Sulphur Anomalous Crystal Structure of Asymmetric IRAK4 Dimer 2014-08-05 2014-09-24 Ferrao, R.,Zhou, H.,Shan, Y.,Liu, Q.,Li, Q.,Shaw, D.E.,Li, X.,Wu, H. IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly. Mol.Cell 2014 55 891 903 4WD7 25324390 Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae by Zn-SAD phasing 2014-09-08 2014-10-01 Yang, T.,Liu, Q.,Kloss, B.,Bruni, R.,Kalathur, R.C.,Guo, Y.,Kloppmann, E.,Rost, B.,Colecraft, H.M.,Hendrickson, W.A. Structure and selectivity in bestrophin ion channels. Science 2014 346 355 359 4RDV The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate 2014-09-19 2014-10-08 Fedorov, A.A.,Fedorov, E.V.,Marti-Arbona, R.,Raushel, F.M.,Almo, S.C. The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate To be Published 0 0 0 0 4RDW The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutaric acid 2014-09-19 2014-10-08 Fedorov, A.A.,Fedorov, E.V.,Marti-Arbona, R.,Raushel, F.M.,Almo, S.C. The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutaric acid To be Published 0 0 0 0 4TKS 25286840 Native-SAD phasing for human EGFR kinase domain. 2014-05-27 2014-10-08 Liu, Q.,Guo, Y.,Chang, Y.,Cai, Z.,Assur, Z.,Mancia, F.,Greene, M.I.,Hendrickson, W.A. Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D 2014 70 2544 2557 4RHP 25339443 Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043 2014-10-02 2014-10-22 Lohman, D.C.,Forouhar, F.,Beebe, E.T.,Stefely, M.S.,Minogue, C.E.,Ulbrich, A.,Stefely, J.A.,Sukumar, S.,Luna-Sanchez, M.,Jochem, A.,Lew, S.,Seetharaman, J.,Xiao, R.,Wang, H.,Westphall, M.S.,Wrobel, R.L.,Everett, J.K.,Mitchell, J.C.,Lopez, L.C.,Coon, J.J.,Tong, L.,Pagliarini, D.J. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proc.Natl.Acad.Sci.USA 2014 111 0 0 4CAZ CRYSTAL STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE FROM Pseudomonas aeruginosa IN COMPLEX WITH NADH 2013-10-09 2014-10-29 Diaz-Sanchez, A.G.,Gonzalez-Segura, L.,Rodriguez-Sotres, R.,Mujica-Jimenez, C.,Munoz-Clares, R.A. The Structural Bases of the Dual Coenzyme Specificity of Betaine Aldehyde Dehydrogenase from Pseudomonas Aeruginosa To be Published 0 0 0 0 4RMM Crystal Structure of the Q7NVP2_CHRVO protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR191 2014-10-21 2014-11-05 Vorobiev, S.,Su, M.,Seetharaman, J.,Mao, L.,Xiao, R.,Ciccosanti, C.,Foote, E.L.,Wang, D.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F. Crystal Structure of the Q7NVP2_CHRVO protein from Chromobacterium violaceum. To be Published 0 0 0 0 4OR7 25288083 Klebsiella pneumoniae dihydrofolate reductase complexed with NADPH and 6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine 2014-02-11 2014-12-03 Lamb, K.M.,Lombardo, M.N.,Alverson, J.,Priestley, N.D.,Wright, D.L.,Anderson, A.C. Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity. Antimicrob.Agents Chemother. 2014 58 7484 7491 4OSG 25288083 Klebsiella pneumoniae complexed with NADPH and 6-ethyl-5-[(3R)-3-[3-methoxyl-5-(pyridine-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006) 2014-02-12 2014-12-03 Lamb, K.M.,Lombardo, M.N.,Alverson, J.,Priestley, N.D.,Wright, D.L.,Anderson, A.C. Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity. Antimicrob.Agents Chemother. 2014 58 7484 7491 4Q6A 25552560 Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH 2014-04-21 2014-12-31 Reeve, S.M.,Gainza, P.,Frey, K.M.,Georgiev, I.,Donald, B.R.,Anderson, A.C. Protein design algorithms predict viable resistance to an experimental antifolate. Proc.Natl.Acad.Sci.USA 2015 112 749 754 4RZB 25559274 The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate, SOAKED WITH MERCURY 2014-12-19 2015-01-14 Fedorov, A.A.,Marti-Arbona, R.,Nemmara, V.V.,Hitchcock, D.,Fedorov, E.V.,Almo, S.C.,Raushel, F.M. Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa. Biochemistry 2015 54 890 897 4RYM 25635100 Crystal structure of BcTSPO Iodo Type1 monomer 2014-12-15 2015-01-28 Guo, Y.,Kalathur, R.C.,Liu, Q.,Kloss, B.,Bruni, R.,Ginter, C.,Kloppmann, E.,Rost, B.,Hendrickson, W.A. Protein structure. Structure and activity of tryptophan-rich TSPO proteins. Science 2015 347 551 555 4ZQ9 26370092 X-ray structure of AAV-2 OBD bound to AAVS1 site 3:1 2015-05-08 2015-09-23 Musayev, F.N.,Zarate-Perez, F.,Bishop, C.,Burgner, J.W.,Escalante, C.R. Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1. J.Biol.Chem. 2015 290 27487 27499 4ZO0 26314310 X-ray Structure of AAV-2 Origin Binding Domain 2015-05-05 2015-10-07 Musayev, F.N.,Zarate-Perez, F.,Bardelli, M.,Bishop, C.,Saniev, E.F.,Linden, R.M.,Henckaerts, E.,Escalante, C.R. Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation. Biochemistry 2015 54 5907 5919 4ZHN Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T 2015-04-25 2015-12-23 Hall, M.L.,Ergel, B.,Miller, E.B.,Yu, B.,Rinaldo, D.,Hunt, J.F.,Friesner, R. DFT Studies of the Rate-Limiting Step in the Reaction Cycle of the Fe/2OG Dioxygenase AlkB and Related Experimental Studies To be published 0 0 0 0 4X3L Crystal Structure of TTHA0275 from Thermus thermophilus (HB8) in complex with 5'-methylthioadenosine in space group P21212 2014-12-01 2016-01-20 Demirci, H.,Belardinelli, R.,Jogl, G. Crystal Structure of TTHA0275 from Thermus thermophilus (HB8) To Be Published 0 0 0 0 4RAU crystal structure of RTOFab in complex with human PF4 2014-09-11 2016-03-16 Cai, Z.,Zhu, Z.,Liu, Q.,Greene, M.I. crystal structure of RTOFab in complex with platelet factor 4 To be Published 0 0 0 0 5K6U 27644106 Sidekick-1 immunoglobulin domains 1-4, crystal form 1 2016-05-25 2016-09-28 Goodman, K.M.,Yamagata, M.,Jin, X.,Mannepalli, S.,Katsamba, P.S.,Ahlsen, G.,Sergeeva, A.P.,Honig, B.,Sanes, J.R.,Shapiro, L. Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife 2016 5 0 0 5UGL 28166054 Crystal Structure of FGF Receptor 2 Tyrosine Kinase Domain Harboring the D650V Activating Mutation 2017-01-09 2017-02-22 Chen, H.,Marsiglia, W.M.,Cho, M.K.,Huang, Z.,Deng, J.,Blais, S.P.,Gai, W.,Bhattacharya, S.,Neubert, T.A.,Traaseth, N.J.,Mohammadi, M. Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. Elife 2017 6 0 0 5UI0 28166054 Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 2 harboring an E565A/K659M Double Gain-of-Function Mutation 2017-01-12 2017-02-22 Chen, H.,Marsiglia, W.M.,Cho, M.K.,Huang, Z.,Deng, J.,Blais, S.P.,Gai, W.,Bhattacharya, S.,Neubert, T.A.,Traaseth, N.J.,Mohammadi, M. Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. Elife 2017 6 0 0 5JRR Crystal structure of native laccase from Thermus thermophilus HB27 2016-05-06 2017-05-10 Diaz-Vilchis, A.,Ruiz-Arellano, R.R.,Rosas-Benitez, E.,Stojanoff, V.,Rudino-Pinera, E. Preserving metallic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase To be Published 0 0 0 0 5K7A Crystal structure of laccase fron Thermus thermophilus HB27 (sodium nitrate 1.5 min) 2016-05-25 2017-06-07 Diaz-Vilchis, A.,Ruiz-Arellano, R.R.,Rosas-Benitez, E.,Stojanoff, V.,Rudino-Pinera, E. Preserving metalic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase To be Published 0 0 0 0 6CG7 29742438 mouse cadherin-22 EC1-2 adhesive fragment 2018-02-19 2018-05-09 Brasch, J.,Katsamba, P.S.,Harrison, O.J.,Ahlsen, G.,Troyanovsky, R.B.,Indra, I.,Kaczynska, A.,Kaeser, B.,Troyanovsky, S.,Honig, B.,Shapiro, L. Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior. Cell Rep 2018 23 1840 1852 6CGB 29742438 chimera of mouse cadherin-11 EC1 and mouse cadherin-6 EC2 2018-02-19 2018-05-09 Brasch, J.,Katsamba, P.S.,Harrison, O.J.,Ahlsen, G.,Troyanovsky, R.B.,Indra, I.,Kaczynska, A.,Kaeser, B.,Troyanovsky, S.,Honig, B.,Shapiro, L. Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior. Cell Rep 2018 23 1840 1852 6EGE 30679311 Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor 2018-08-19 2019-02-13 Wang, L.,Ferrao, R.,Li, Q.,Hatcher, J.M.,Choi, H.G.,Buhrlage, S.J.,Gray, N.S.,Wu, H. Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). J.Biol.Chem. 2019 294 4511 4519 6OCT 30971491 Crystal structure of human KCTD16 T1 domain 2019-03-25 2019-04-10 Zuo, H.,Glaaser, I.,Zhao, Y.,Kurinov, I.,Mosyak, L.,Wang, H.,Liu, J.,Park, J.,Frangaj, A.,Sturchler, E.,Zhou, M.,McDonald, P.,Geng, Y.,Slesinger, P.A.,Fan, Q.R. Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA 2019 116 8370 8379 6OE2 31794207 X-Ray Structure of the C-terminal domain (277-440) of Putative chitobiase from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR324A. Re-refinement of 3GGL with correct metal Mn replacing Zn. New metal confirmed with PIXE analysis of original sample. 2019-03-27 2019-12-25 Grime, G.W.,Zeldin, O.B.,Snell, M.E.,Lowe, E.D.,Hunt, J.F.,Montelione, G.T.,Tong, L.,Snell, E.H.,Garman, E.F. High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application. J.Am.Chem.Soc. 2020 142 185 197 6PNX 31959966 Crystal Structure of an Asymmetric Dimer of FGF Receptor 3 Kinases Trapped in A-loop Tyrosine Transphosphorylation Reaction 2019-07-03 2020-01-22 Chen, L.,Marsiglia, W.M.,Chen, H.,Katigbak, J.,Erdjument-Bromage, H.,Kemble, D.J.,Fu, L.,Ma, J.,Sun, G.,Zhang, Y.,Liang, G.,Neubert, T.A.,Li, X.,Traaseth, N.J.,Mohammadi, M. Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation. Nat.Chem.Biol. 2020 16 267 277 8EGK 37100288 Re-refinement of Crystal Structure of NosGet3d, the All4481 protein from Nostoc sp. PCC 7120 2022-09-12 2023-05-24 Barlow, A.N.,Manu, M.S.,Saladi, S.M.,Tarr, P.T.,Yadav, Y.,Thinn, A.M.M.,Zhu, Y.,Laganowsky, A.D.,Clemons Jr., W.M.,Ramasamy, S. Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis. J.Biol.Chem. 2023 299 104752 104752 8EGK 37100288 Re-refinement of Crystal Structure of NosGet3d, the All4481 protein from Nostoc sp. PCC 7120 2022-09-12 2023-05-24 Barlow, A.N.,Manu, M.S.,Saladi, S.M.,Tarr, P.T.,Yadav, Y.,Thinn, A.M.M.,Zhu, Y.,Laganowsky, A.D.,Clemons Jr., W.M.,Ramasamy, S. Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis. J.Biol.Chem. 2023 299 104752 104752