PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 1PTY CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO PHOSPHOTYROSINE MOLECULES 1997-01-16 1998-01-21 Puius, Y.A.,Zhao, Y.,Sullivan, M.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. Proc.Natl.Acad.Sci.USA 1997 94 13420 13425 1G3P CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAINS OF BACTERIOPHAGE MINOR COAT PROTEIN G3P 1997-12-22 1998-01-28 Lubkowski, J.,Hennecke, F.,Pluckthun, A.,Wlodawer, A. The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p. Nat.Struct.Biol. 1998 5 140 147 1AAX CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO BIS(PARA-PHOSPHOPHENYL)METHANE (BPPM) MOLECULES 1997-01-16 1998-03-04 Puius, Y.A.,Zhao, Y.,Sullivan, M.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. Proc.Natl.Acad.Sci.USA 1997 94 13420 13425 1BO1 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE II BETA 1998-08-02 1998-10-07 Rao, V.D.,Misra, S.,Boronenkov, I.V.,Anderson, R.A.,Hurley, J.H. Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell(Cambridge,Mass.) 1998 94 829 839 1AQU ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL 1997-08-01 1998-10-28 Kakuta, Y.,Pedersen, L.G.,Carter, C.W.,Negishi, M.,Pedersen, L.C. Crystal structure of estrogen sulphotransferase. Nat.Struct.Biol. 1997 4 904 908 1AQY ESTROGEN SULFOTRANSFERASE WITH PAP 1997-08-04 1998-10-28 Kakuta, Y.,Pedersen, L.G.,Carter, C.W.,Negishi, M.,Pedersen, L.C. Crystal structure of estrogen sulphotransferase. Nat.Struct.Biol. 1997 4 904 908 1B8N 12463747 PURINE NUCLEOSIDE PHOSPHORYLASE 1999-02-02 1999-02-08 Kicska, G.A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Shi, W.,Fedorov, A.A.,Lewandowicz, A.,Cahill, S.M.,Almo, S.C.,Schramm, V.L. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase Biochemistry 2002 41 14489 14498 1B8O 11170405 PURINE NUCLEOSIDE PHOSPHORYLASE 1999-02-02 1999-02-08 Fedorov, A.,Shi, W.,Kicska, G.,Fedorov, E.,Tyler, P.C.,Furneaux, R.H.,Hanson, J.C.,Gainsford, G.J.,Larese, J.Z.,Schramm, V.L.,Almo, S.C. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis. Biochemistry 2001 40 853 860 2DL2 10097129 KILLER IMMUNOGLOBULIN RECEPTOR 2DL2 1999-03-08 1999-03-30 Snyder, G.A.,Brooks, A.G.,Sun, P.D. Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2 Proc.Natl.Acad.Sci.USA 1999 96 3864 3869 1B3A TOTAL CHEMICAL SYNTHESIS AND HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE POTENT ANTI-HIV PROTEIN AOP-RANTES 1998-12-07 1999-04-23 Wilken, J.,Hoover, D.,Thompson, D.A.,Barlow, P.N.,McSparron, H.,Picard, L.,Wlodawer, A.,Lubkowski, J.,Kent, S.B. Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES. Chem.Biol. 1999 6 43 51 1VFY 10367894 PHOSPHATIDYLINOSITOL-3-PHOSPHATE BINDING FYVE DOMAIN OF VPS27P PROTEIN FROM SACCHAROMYCES CEREVISIAE 1999-04-26 1999-05-06 Misra, S.,Hurley, J.H. Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p. Cell(Cambridge,Mass.) 1999 97 657 666 1QBZ 10388624 THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A 1999-04-28 1999-05-17 Yang, Z.N.,Mueser, T.C.,Kaufman, J.,Stahl, S.J.,Wingfield, P.T.,Hyde, C.C. The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution. J.Struct.Biol. 1999 126 131 144 1QC6 10404224 EVH1 domain from ENA/VASP-like protein in complex with ACTA peptide 1999-05-17 1999-05-25 Fedorov, A.A.,Fedorov, E.,Gertler, F.,Almo, S.C. Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function Nat.Struct.Biol. 1999 6 661 665 1LZ8 10339407 LYSOZYME PHASED ON ANOMALOUS SIGNAL OF SULFURS AND CHLORINES 1999-03-14 1999-05-26 Dauter, Z.,Dauter, M.,de La Fortelle, E.,Bricogne, G.,Sheldrick, G.M. Can anomalous signal of sulfur become a tool for solving protein crystal structures? J.Mol.Biol. 1999 289 83 92 1LZ9 10339408 ANOMALOUS SIGNAL OF SOLVENT BROMINES USED FOR PHASING OF LYSOZYME 1999-03-15 1999-05-26 Dauter, Z.,Dauter, M. Anomalous signal of solvent bromides used for phasing of lysozyme. J.Mol.Biol. 1999 289 93 101 1HKA 10378268 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE 1998-09-29 1999-06-08 Xiao, B.,Shi, G.,Chen, X.,Yan, H.,Ji, X. Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents. Structure Fold.Des. 1999 7 489 496 1B6E 10023772 HUMAN CD94 1999-01-14 1999-06-15 Boyington, J.C.,Riaz, A.N.,Patamawenu, A.,Coligan, J.E.,Brooks, A.G.,Sun, P.D. Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors. Immunity 1999 10 75 82 1BZY 10360366 HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR 1998-11-05 1999-06-22 Shi, W.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor. Nat.Struct.Biol. 1999 6 588 593 2HEX 10089443 DECAMERS OBSERVED IN THE CRYSTALS OF BOVINE PANCREATIC TRYPSIN INHIBITOR 1998-08-01 1999-08-05 Lubkowski, J.,Wlodawer, A. Decamers observed in the crystals of bovine pancreatic trypsin inhibitor. Acta Crystallogr.,Sect.D 1999 55 335 337 1SVY 10820002 SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE 1998-08-10 1999-08-10 Puius, Y.A.,Fedorov, E.V.,Eichinger, L.,Schleicher, M.,Almo, S.C. Mapping the functional surface of domain 2 in the gelsolin superfamily. Biochemistry 2000 39 5322 5331 1CJB 10433693 MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE 1999-04-08 1999-08-18 Shi, W.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Cahill, S.M.,Girvin, M.E.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor. Biochemistry 1999 38 9872 9880 1CXQ 10521258 ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM AMMONIUM SULFATE 1999-08-30 1999-09-08 Lubkowski, J.,Dauter, Z.,Yang, F.,Alexandratos, J.,Merkel, G.,Skalka, A.M.,Wlodawer, A. Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant. Biochemistry 1999 38 13512 13522 1CXU 10521258 1.42A RESOLUTION ASV INTEGRASE CORE DOMAIN FROM CITRATE 1999-08-30 1999-09-08 Lubkowski, J.,Dauter, Z.,Yang, F.,Alexandratos, J.,Merkel, G.,Skalka, A.M.,Wlodawer, A. Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant. Biochemistry 1999 38 13512 13522 1CZ9 10521258 ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN (D64N) FROM CITRATE 1999-09-01 1999-09-08 Lubkowski, J.,Dauter, Z.,Yang, F.,Alexandratos, J.,Merkel, G.,Skalka, A.M.,Wlodawer, A. Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant. Biochemistry 1999 38 13512 13522 1CZB 10521258 ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM HEPES 1999-09-01 1999-09-08 Lubkowski, J.,Dauter, Z.,Yang, F.,Alexandratos, J.,Merkel, G.,Skalka, A.M.,Wlodawer, A. Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant. Biochemistry 1999 38 13512 13522 1CVJ 10499800 X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA 1999-08-23 1999-10-04 Deo, R.C.,Bonanno, J.B.,Sonenberg, N.,Burley, S.K. Recognition of polyadenylate RNA by the poly(A)-binding protein. Cell(Cambridge,Mass.) 1999 98 835 845 1YAG 12732734 STRUCTURE OF THE YEAST ACTIN-HUMAN GELSOLIN SEGMENT 1 COMPLEX 1998-10-09 1999-10-09 Vorobiev, S.,Strokopytov, B.,Drubin, D.G.,Frieden, C.,Ono, S.,Condeelis, J.,Rubenstein, P.A.,Almo, S.C. The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism Proc.Natl.Acad.Sci.USA 2003 100 5760 5765 1D3R 10606513 CRYSTAL STRUCTURE OF TRIPLEX DNA 1999-09-30 2000-01-01 Rhee, S.,Han, Z.,Liu, K.,Miles, H.T.,Davies, D.R. Structure of a triple helical DNA with a triplex-duplex junction. Biochemistry 1999 38 16810 16815 1QMH 10673421 Crystal structure of RNA 3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology 1999-09-28 2000-01-11 Palm, G.J.,Billy, E.,Filipowicz, W.,Wlodawer, A. Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology Structure 2000 8 13 0 1QMI 10673421 Crystal structure of RNA 3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology 1999-09-28 2000-01-11 Palm, G.J.,Billy, E.,Filipowicz, W.,Wlodawer, A. Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology Structure 2000 8 13 0 2DLI 10097129 KILLER IMMUNOGLOBULIN RECEPTOR 2DL2,TRIGONAL FORM 1999-03-08 2000-01-13 Snyder, G.A.,Brooks, A.G.,Sun, P.D. Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2 Proc.Natl.Acad.Sci.USA 1999 96 3864 3869 1B6B 10024876 MELATONIN BIOSYNTHESIS: THE STRUCTURE OF SEROTONIN N-ACETYLTRANSFERASE AT 2.5 A RESOLUTION SUGGESTS A CATALYTIC MECHANISM 1999-01-13 2000-01-14 Hickman, A.B.,Klein, D.C.,Dyda, F. Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism. Mol.Cell 1999 3 23 32 1C1K 10669611 BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN 1999-07-22 2000-02-16 Mueser, T.C.,Jones, C.E.,Nossal, N.G.,Hyde, C.C. Bacteriophage T4 gene 59 helicase assembly protein binds replication fork DNA. The 1.45 A resolution crystal structure reveals a novel alpha-helical two-domain fold. J.Mol.Biol. 2000 296 597 613 1C0M 10669607 CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE 1999-07-16 2000-03-01 Yang, Z.N.,Mueser, T.C.,Bushman, F.D.,Hyde, C.C. Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase. J.Mol.Biol. 2000 296 535 548 1C1A 10669607 CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE 1999-07-21 2000-03-01 Yang, Z.N.,Mueser, T.C.,Bushman, F.D.,Hyde, C.C. Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase. J.Mol.Biol. 2000 296 535 548 1C5E 10700283 BACTERIOPHAGE LAMBDA HEAD PROTEIN D 1999-11-18 2000-03-08 Yang, F.,Forrer, P.,Dauter, Z.,Conway, J.F.,Cheng, N.,Cerritelli, M.E.,Steven, A.C.,Pluckthun, A.,Wlodawer, A. Novel fold and capsid-binding properties of the lambda-phage display platform protein gpD. Nat.Struct.Biol. 2000 7 230 237 1ELK 10985773 VHS domain of TOM1 protein from H. sapiens 2000-03-13 2000-03-22 Misra, S.,Beach, B.,Hurley, J.H. Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes Biochemistry 2000 39 11282 11290 1YVN THE YEAST ACTIN VAL 159 ASN MUTANT COMPLEX WITH HUMAN GELSOLIN SEGMENT 1. 1999-03-23 2000-03-23 Vorobiev, S.M.,Belmont, L.D.,Drubin, D.D.,Almos, C. Crystal structure of yeast actin V159N mutant To be Published 0 0 0 0 1EQT MET-RANTES 2000-04-06 2000-04-19 Hoover, D.M.,Shaw, J.,Gryczynski, Z.,Proudfoot, A.E.I.,Wells, T. The Crystal Structure of MET-RANTES: Comparison with Native RANTES and AOP-RANTES PROTEIN PEPT.LETT. 2000 7 73 82 1DP5 10655612 THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT INHIBITOR 1999-12-23 2000-05-03 Li, M.,Phylip, L.H.,Lees, W.E.,Winther, J.R.,Dunn, B.M.,Wlodawer, A.,Kay, J.,Gustchina, A. The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol. 2000 7 113 117 1DPJ 10655612 THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR 1999-12-27 2000-05-03 Li, M.,Phylip, L.H.,Lees, W.E.,Winther, J.R.,Dunn, B.M.,Wlodawer, A.,Kay, J.,Gustchina, A. The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol. 2000 7 113 117 1ES9 11239086 X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) 2000-04-07 2000-05-31 McMullen, T.W.,Li, J.,Sheffield, P.J.,Aoki, J.,Martin, T.W.,Arai, H.,Inoue, K.,Derewenda, Z.S. The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib). Protein Eng. 2000 13 865 871 1F2K CRYSTAL STRUCTURE OF ACANTHAMOEBA CASTELLANII PROFILIN II, CUBIC CRYSTAL FORM 2000-05-26 2000-06-08 Fedorov, A.A.,Shi, W.,Mahoney, N.,Kaiser, D.A.,Almo, S.C. A Comparative Structural Analysis of Profilins To be Published 0 0 0 0 1EFX 10850706 STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3 2000-02-10 2000-06-14 Boyington, J.C.,Motyka, S.A.,Schuck, P.,Brooks, A.G.,Sun, P.D. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 2000 405 537 543 1DQN 10841757 CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE 2000-01-04 2000-07-26 Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry 2000 39 6781 6790 1DQP 10841757 CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING 2000-01-04 2000-07-26 Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry 2000 39 6781 6790 1CI4 10924106 THE CRYSTAL STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR (BAF) 1999-04-07 2000-08-16 Umland, T.C.,Wei, S.Q.,Craigie, R.,Davies, D.R. Structural basis of DNA bridging by barrier-to-autointegration factor. Biochemistry 2000 39 9130 9138 1DC3 10978154 STRUCTURAL ANALYSIS OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM ESCHERICHIA COLI: DIRECT EVIDENCE FOR SUBSTRATE BINDING AND COFACTOR-INDUCED CONFORMATIONAL CHANGES 1999-11-04 2000-08-23 Yun, M.,Park, C.G.,Kim, J.Y.,Park, H.W. Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes. Biochemistry 2000 39 10702 10710 1EFH 10854859 CRYSTAL STRUCTURE OF THE HUMAN HYDROXYSTEROID SULFOTRANSFERASE IN THE PRESENCE OF PAP 2000-02-08 2000-09-06 Pedersen, L.C.,Petrotchenko, E.V.,Negishi, M. Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase. FEBS Lett. 2000 475 61 64 1F2L 10770945 CRYSTAL STRUCTURE OF CHEMOKINE DOMAIN OF FRACTALKINE 2000-05-26 2000-09-06 Hoover, D.M.,Mizoue, L.S.,Handel, T.M.,Lubkowski, J. The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement. J.Biol.Chem. 2000 275 23187 23193 1F3A 11027134 CRYSTAL STRUCTURE OF MGSTA1-1 IN COMPLEX WITH GSH 2000-06-01 2000-10-18 Gu, Y.,Singh, S.V.,Ji, X. Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide. Biochemistry 2000 39 12552 12557 1F3B 11027134 CRYSTAL STRUCTURE OF MGSTA1-1 IN COMPLEX WITH GLUTATHIONE CONJUGATE OF BENZO[A]PYRENE EPOXIDE 2000-06-01 2000-10-18 Gu, Y.,Singh, S.V.,Ji, X. Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide. Biochemistry 2000 39 12552 12557 1DQT 11052947 THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152) 2000-01-05 2000-10-27 Ostrov, D.A.,Shi, W.,Schwartz, J.C.,Almo, S.C.,Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science 2000 290 816 819 1FD3 10906336 HUMAN BETA-DEFENSIN 2 2000-07-19 2000-11-01 Hoover, D.M.,Rajashankar, K.R.,Blumenthal, R.,Puri, A.,Oppenheim, J.J.,Chertov, O.,Lubkowski, J. The structure of human beta-defensin-2 shows evidence of higher order oligomerization. J.Biol.Chem. 2000 275 32911 32918 1FD4 10906336 HUMAN BETA-DEFENSIN 2 2000-07-19 2000-11-01 Hoover, D.M.,Rajashankar, K.R.,Blumenthal, R.,Puri, A.,Oppenheim, J.J.,Chertov, O.,Lubkowski, J. The structure of human beta-defensin-2 shows evidence of higher order oligomerization. J.Biol.Chem. 2000 275 32911 32918 1F5M 11032796 STRUCTURE OF THE GAF DOMAIN 2000-06-15 2000-11-10 Ho, Y.S.,Burden, L.M.,Hurley, J.H. Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor. EMBO J. 2000 19 5288 5299 1FSI 11080166 CRYSTAL STRUCTURE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF APPR>P FROM ARABIDOPSIS THALIANA 2000-09-10 2000-11-22 Hofmann, A.,Zdanov, A.,Genschik, P.,Ruvinov, S.,Filipowicz, W.,Wlodawer, A. Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction. EMBO J. 2000 19 6207 6217 1FSI 11080166 CRYSTAL STRUCTURE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF APPR>P FROM ARABIDOPSIS THALIANA 2000-09-10 2000-11-22 Hofmann, A.,Zdanov, A.,Genschik, P.,Ruvinov, S.,Filipowicz, W.,Wlodawer, A. Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction. EMBO J. 2000 19 6207 6217 1FSI 11080166 CRYSTAL STRUCTURE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF APPR>P FROM ARABIDOPSIS THALIANA 2000-09-10 2000-11-22 Hofmann, A.,Zdanov, A.,Genschik, P.,Ruvinov, S.,Filipowicz, W.,Wlodawer, A. Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction. EMBO J. 2000 19 6207 6217 1FSI 11080166 CRYSTAL STRUCTURE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF APPR>P FROM ARABIDOPSIS THALIANA 2000-09-10 2000-11-22 Hofmann, A.,Zdanov, A.,Genschik, P.,Ruvinov, S.,Filipowicz, W.,Wlodawer, A. Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction. EMBO J. 2000 19 6207 6217 1G5U LATEX PROFILIN HEVB8 2000-11-02 2000-11-22 Fedorov, A.A.,Fedorov, E.V.,Ganglberger, E.,Breiteneder, H.,Almo, S.C. A Comparative Structural Analysis of Allergen Profilins HEVB8 and BETV2 To be Published 0 0 0 0 1G61 11101899 CRYSTAL STRUCTURE OF M.JANNASCHII EIF6 2000-11-02 2000-11-22 Groft, C.M.,Beckmann, R.,Sali, A.,Burley, S.K. Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol. 2000 7 1156 1164 1FJ2 11080636 Crystal structure of the human acyl protein thioesterase 1 at 1.5 A resolution 2000-08-07 2000-11-29 Devedjiev, Y.,Dauter, Z.,Kuznetsov, S.R.,Jones, T.L.,Derewenda, Z.S. Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A. Structure Fold.Des. 2000 8 1137 1146 1ESR 11087354 CRYSTAL STRUCTURE OF HUMAN MONOCYTE CHEMOTACTIC PROTEIN-2 2000-04-10 2000-12-06 Blaszczyk, J.,Coillie, E.V.,Proost, P.,Damme, J.V.,Opdenakker, G.,Bujacz, G.D.,Wang, J.M.,Ji, X. Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors. Biochemistry 2000 39 14075 14081 1G7R 11114334 X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B 2000-11-14 2000-12-06 Roll-Mecak, A.,Cao, C.,Dever, T.E.,Burley, S.K. X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding. Cell(Cambridge,Mass.) 2000 103 781 792 1FU1 11080143 CRYSTAL STRUCTURE OF HUMAN XRCC4 2000-09-13 2000-12-11 Junop, M.S.,Modesti, M.,Guarne, A.,Ghirlando, R.,Gellert, M.,Yang, W. Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J. 2000 19 5962 5970 1GA1 11173470 CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF IODOTYROSTATIN (THIS ENZYME RENAMED ""SEDOLISIN"" IN 2003) 2000-11-29 2000-12-13 Dauter, Z.,Li, M.,Wlodawer, A. Practical experience with the use of halides for phasing macromolecular structures: a powerful tool for structural genomics. Acta Crystallogr.,Sect.D 2001 57 239 249 1GA4 11323721 CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH INHIBITOR PSEUDOIODOTYROSTATIN (THIS ENZYME RENAMED ""SEDOLISIN"" IN 2003) 2000-11-29 2000-12-13 Wlodawer, A.,Li, M.,Dauter, Z.,Gustchina, A.,Uchida, K.,Oyama, H.,Dunn, B.M.,Oda, K. Carboxyl proteinase from Pseudomonas defines a novel family of subtilisin-like enzymes. Nat.Struct.Biol. 2001 8 442 446 1GA6 11323721 CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF TYROSTATIN (THIS ENZYME RENAMED ""SEDOLISIN"" IN 2003) 2000-11-29 2000-12-13 Wlodawer, A.,Li, M.,Dauter, Z.,Gustchina, A.,Uchida, K.,Oyama, H.,Dunn, B.M.,Oda, K. Carboxyl proteinase from Pseudomonas defines a novel family of subtilisin-like enzymes. Nat.Struct.Biol. 2001 8 442 446 1D1J 10600384 CRYSTAL STRUCTURE OF HUMAN PROFILIN II 1999-09-17 2000-12-22 Nodelman, I.M.,Bowman, G.D.,Lindberg, U.,Schutt, C.E. X-ray structure determination of human profilin II: A comparative structural analysis of human profilins. J.Mol.Biol. 1999 294 1271 1285 1EEN 10889023 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G 2000-02-01 2001-02-01 Sarmiento, M.,Puius, Y.A.,Vetter, S.W.,Keng, Y.F.,Wu, L.,Zhao, Y.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition. Biochemistry 2000 39 8171 8179 1EEO 10889023 CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 2000-02-01 2001-02-01 Sarmiento, M.,Puius, Y.A.,Vetter, S.W.,Keng, Y.F.,Wu, L.,Zhao, Y.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition. Biochemistry 2000 39 8171 8179 1FXL 11175903 CRYSTAL STRUCTURE OF HUD AND AU-RICH ELEMENT OF THE C-FOS RNA 2000-09-26 2001-02-05 Wang, X.,Tanaka Hall, T.M. Structural basis for recognition of AU-rich element RNA by the HuD protein. Nat.Struct.Biol. 2001 8 141 145 1HQO 11171973 CRYSTAL STRUCTURE OF THE NITROGEN REGULATION FRAGMENT OF THE YEAST PRION PROTEIN URE2P 2000-12-18 2001-02-14 Umland, T.C.,Taylor, K.L.,Rhee, S.,Wickner, R.B.,Davies, D.R. The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. Proc.Natl.Acad.Sci.USA 2001 98 1459 1464 1EX6 11243817 CRYSTAL STRUCTURE OF UNLIGANDED FORM OF GUANYLATE KINASE FROM YEAST 2000-05-01 2001-03-16 Blaszczyk, J.,Li, Y.,Yan, H.,Ji, X. Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes. J.Mol.Biol. 2001 307 247 257 1I85 11279501 CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX 2001-03-12 2001-04-04 Schwartz, J.C.,Zhang, X.,Fedorov, A.A.,Nathenson, S.G.,Almo, S.C. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature 2001 410 604 608 1EQM 11546767 CRYSTAL STRUCTURE OF BINARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE WITH ADENOSINE-5'-DIPHOSPHATE 2000-04-05 2001-04-05 Xiao, B.,Shi, G.,Gao, J.,Blaszczyk, J.,Liu, Q.,Ji, X.,Yan, H. Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR. J.Biol.Chem. 2001 276 40274 40281 1G0V 11042188 THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV 2000-10-09 2001-04-21 Phylip, L.H.,Lees, W.E.,Brownsey, B.G.,Bur, D.,Dunn, B.M.,Winther, J.R.,Gustchina, A.,Li, M.,Copeland, T.,Wlodawer, A.,Kay, J. The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae. J.Biol.Chem. 2001 276 2023 2030 1D4X 12732734 Crystal Structure of Caenorhabditis Elegans Mg-ATP Actin Complexed with Human Gelsolin Segment 1 at 1.75 A resolution. 1999-10-06 2001-05-02 Vorobiev, S.,Strokopytov, B.,Drubin, D.G.,Frieden, C.,Ono, S.,Condeelis, J.,Rubenstein, P.A.,Almo, S.C. The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism. Proc.Natl.Acad.Sci.Usa 2003 100 5760 5765 1FSO 11320308 CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI QUADRUPLE MUTANT 2000-09-11 2001-05-02 Longenecker, K.L.,Garrard, S.M.,Sheffield, P.J.,Derewenda, Z.S. Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI. Acta Crystallogr.,Sect.D 2001 57 679 688 1IIN 11373625 thymidylyltransferase complexed with UDP-glucose 2001-04-23 2001-05-09 Barton, W.A.,Lesniak, J.,Biggins, J.B.,Jeffrey, P.D.,Jiang, J.,Rajashankar, K.R.,Thorson, J.S.,Nikolov, D.B. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat.Struct.Biol. 2001 8 545 551 1JD1 12112709 Crystal Structure of YEO7_yeast 2001-06-12 2001-07-04 Deaconescu, A.M.,Roll-Mecak, A.,Bonanno, J.B.,Gerchman, S.E.,Kycia, H.,Studier, F.W.,Burley, S.K. X-ray structure of Saccharomyces cerevisiae homologous mitochondrial matrix factor 1 (Hmf1). Proteins 2002 48 431 436 1HTJ 11470431 STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF 2000-12-29 2001-07-11 Longenecker, K.L.,Lewis, M.E.,Chikumi, H.,Gutkind, J.S.,Derewenda, Z.S. Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases. Structure 2001 9 559 569 1G2O 11444966 CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR 2000-10-20 2001-08-01 Shi, W.,Basso, L.A.,Santos, D.S.,Tyler, P.C.,Furneaux, R.H.,Blanchard, J.S.,Almo, S.C.,Schramm, V.L. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry 2001 40 8204 8215 1I80 11444966 CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION 2001-03-12 2001-08-01 Shi, W.,Basso, L.A.,Santos, D.S.,Tyler, P.C.,Furneaux, R.H.,Blanchard, J.S.,Almo, S.C.,Schramm, V.L. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry 2001 40 8204 8215 1IHR 11328822 Crystal structure of the dimeric C-terminal domain of TonB 2001-04-20 2001-08-01 Chang, C.,Mooser, A.,Pluckthun, A.,Wlodawer, A. Crystal structure of the dimeric C-terminal domain of TonB reveals a novel fold. J.Biol.Chem. 2001 276 27535 27540 1HG1 11341830 X-ray structure of the complex between Erwinia chrysanthemi L-asparaginase and D-aspartate 2000-12-08 2001-08-07 Kolyani, K.A.,Wlodawer, A.,Lubkowski, J. Stuctural Basis for the Activity and Substrate Specificity of Erwinia Chrysanthemi L-Asparaginase Biochemistry 2001 40 5655 0 1JX4 11595188 Crystal Structure of a Y-family DNA Polymerase in a Ternary Complex with DNA Substrates and an Incoming Nucleotide 2001-09-05 2001-10-05 Ling, H.,Boudsocq, F.,Woodgate, R.,Yang, W. Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell(Cambridge,Mass.) 2001 107 91 102 1JXL 11595188 Crystal Structure of a Y-Family DNA Polymerase in a Ternary Complex with DNA Substrates and an Incoming Nucleotide 2001-09-07 2001-10-05 Ling, H.,Boudsocq, F.,Woodgate, R.,Yang, W. Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell(Cambridge,Mass.) 2001 107 91 102 1G9U 11575934 CRYSTAL STRUCTURE OF YOPM-LEUCINE RICH EFFECTOR PROTEIN FROM YERSINIA PESTIS 2000-11-28 2001-10-10 Evdokimov, A.G.,Anderson, D.E.,Routzahn, K.M.,Waugh, D.S. Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit. J.Mol.Biol. 2001 312 807 821 1JL5 11575934 Novel Molecular Architecture of YopM-a Leucine-rich Effector Protein from Yersinia pestis 2001-07-15 2001-10-10 Evdokimov, A.G.,Anderson, D.E.,Routzahn, K.M.,Waugh, D.S. Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit. J.Mol.Biol. 2001 312 807 821 1IJU 11486002 HUMAN BETA-DEFENSIN-1 2001-04-30 2001-10-24 Hoover, D.M.,Chertov, O.,Lubkowski, J. The structure of human beta-defensin-1: new insights into structural properties of beta-defensins. J.Biol.Chem. 2001 276 39021 39026 1IJV 11486002 HUMAN BETA-DEFENSIN-1 2001-04-30 2001-10-24 Hoover, D.M.,Chertov, O.,Lubkowski, J. The structure of human beta-defensin-1: new insights into structural properties of beta-defensins. J.Biol.Chem. 2001 276 39021 39026 1K6Z 11856824 Crystal Structure of the Yersinia Secretion Chaperone SycE 2001-10-17 2001-10-31 Evdokimov, A.G.,Tropea, J.E.,Routzahn, K.M.,Waugh, D.S. Three-dimensional structure of the type III secretion chaperone SycE from Yersinia pestis. Acta Crystallogr.,Sect.D 2002 58 398 406 1H7S 11574484 N-terminal 40kDa fragment of human PMS2 2001-07-10 2001-11-27 Guarne, A.,Junop, M.S.,Yang, W. Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase Embo J. 2001 20 5521 0 1G2P 11535055 CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE 2000-10-20 2001-12-05 Shi, W.,Tanaka, K.S.,Crother, T.R.,Taylor, M.W.,Almo, S.C.,Schramm, V.L. Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae. Biochemistry 2001 40 10800 10809 1G2Q 11535055 CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE 2000-10-20 2001-12-05 Shi, W.,Tanaka, K.S.,Crother, T.R.,Taylor, M.W.,Almo, S.C.,Schramm, V.L. Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae. Biochemistry 2001 40 10800 10809 1I4S 11738048 CRYSTAL STRUCTURE OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.15 ANGSTROM RESOLUTION 2001-02-22 2001-12-19 Blaszczyk, J.,Tropea, J.E.,Bubunenko, M.,Routzahn, K.M.,Waugh, D.S.,Court, D.L.,Ji, X. Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure 2001 9 1225 1236 1JFZ 11738048 Crystal Structure of MN(II)-Complex of RNAse III Endonuclease Domain from Aquifex Aeolicus at 2.10 Angstrom Resolution 2001-06-22 2001-12-19 Blaszczyk, J.,Tropea, J.E.,Bubunenko, M.,Routzahn, K.M.,Waugh, D.S.,Court, D.L.,Ji, X. Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure 2001 9 1225 1236 1K6U 11734212 Crystal Structure of Cyclic Bovine Pancreatic Trypsin Inhibitor 2001-10-17 2001-12-19 Botos, I.,Wu, Z.,Lu, W.,Wlodawer, A. Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor. FEBS Lett. 2001 509 90 94 1HQZ 15735338 Cofilin homology domain of a yeast actin-binding protein ABP1P 2000-12-20 2001-12-21 Strokopytov, B.V.,Fedorov, A.,Mahoney, N.M.,Kessels, M.,Drubin, D.G.,Almo, S.C. Phased translation function revisited: structure solution of the cofilin-homology domain from yeast actin-binding protein 1 using six-dimensional searches. Acta Crystallogr.,Sect.D 2005 61 285 293 1K6Y 11743009 Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase 2001-10-17 2001-12-21 Wang, J.Y.,Ling, H.,Yang, W.,Craigie, R. Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J. 2001 20 7333 7343 1KCG 11754823 NKG2D in complex with ULBP3 2001-11-08 2002-01-09 Radaev, S.,Rostro, B.,Brooks, A.G.,Colonna, M.,Sun, P.D. Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. Immunity 2001 15 1039 1049 1H4R 11856822 Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. 2001-05-14 2002-01-16 Kang, B.S.,Cooper, D.R.,Devedjiev, Y.,Derewenda, U.,Derewenda, Z.S. The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D 2002 58 381 0 1KQ5 C-terminal Domain of Cyclase Associated Protein with PRO 505 Replaced by SER (P505S) 2002-01-03 2002-01-16 Fedorov, A.A.,Dodatko, T.,Roswarski, D.A.,Almo, S.C. Mutant Structures of the Actin-binding Domain of Cyclase Associated Protein (CAP) from Saccharomyces Cerevisiae To be Published 0 0 0 0 1JH6 11694509 Semi-reduced Cyclic Nucleotide Phosphodiesterase from Arabidopsis thaliana 2001-06-27 2002-02-06 Hofmann, A.,Grella, M.,Botos, I.,Filipowicz, W.,Wlodawer, A. Crystal structures of the semireduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana. J.Biol.Chem. 2002 277 1419 1425 1JH7 11694509 Semi-reduced Inhibitor-bound Cyclic Nucleotide Phosphodiesterase from Arabidopsis thaliana 2001-06-27 2002-02-06 Hofmann, A.,Grella, M.,Botos, I.,Filipowicz, W.,Wlodawer, A. Crystal structures of the semireduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana. J.Biol.Chem. 2002 277 1419 1425 1JPL 11859375 GGA3 VHS domain complexed with C-terminal peptide from cation-independent mannose 6-phosphate receptor 2001-08-02 2002-02-27 Misra, S.,Puertollano, R.,Kato, Y.,Bonifacino, J.S.,Hurley, J.H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 2002 415 933 937 1JUQ 11859375 GGA3 VHS domain complexed with C-terminal peptide from cation-dependent Mannose 6-phosphate receptor 2001-08-26 2002-02-27 Misra, S.,Puertollano, R.,Kato, Y.,Bonifacino, J.S.,Hurley, J.H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 2002 415 933 937 1K4Z 15311924 C-terminal Domain of Cyclase Associated Protein 2001-10-09 2002-03-13 Dodatko, T.,Fedorov, A.A.,Grynberg, M.,Patskovsky, Y.,Rozwarski, D.A.,Jaroszewski, L.,Aronoff-Spencer, E.,Kondraskina, E.,Irving, T.,Godzik, A.,Almo, S.C. Crystal structure of the actin binding domain of the cyclase-associated protein Biochemistry 2004 43 10628 10641 1KTB 12005440 The Structure of alpha-N-Acetylgalactosaminidase 2002-01-15 2002-03-15 Garman, S.C.,Hannick, L.,Zhu, A.,Garboczi, D.N. The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases Structure 2002 10 425 434 1KTC 12005440 The Structure of alpha-N-Acetylgalactosaminidase 2002-01-15 2002-03-15 Garman, S.C.,Hannick, L.,Zhu, A.,Garboczi, D.N. The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases. Structure 2002 10 425 434 1INQ 11751972 Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db 2001-05-14 2002-03-20 Ostrov, D.A.,Roden, M.M.,Shi, W.,Palmieri, E.,Christianson, G.J.,Mendoza, L.,Villaflor, G.,Tilley, D.,Shastri, N.,Grey, H.,Almo, S.C.,Roopenian, D.,Nathenson, S.G. How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. J.Immunol. 2002 168 283 289 1JUF 11751972 Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db 2001-08-24 2002-03-20 Ostrov, D.A.,Roden, M.M.,Shi, W.,Palmieri, E.,Christianson, G.J.,Mendoza, L.,Villaflor, G.,Tilley, D.,Shastri, N.,Grey, H.,Almo, S.C.,Roopenian, D.,Nathenson, S.G. How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. J.Immunol. 2002 168 283 289 1K2A 11916383 Modified Form of Eosinophil-derived Neurotoxin 2001-09-26 2002-04-03 Chang, C.,Newton, D.L.,Rybak, S.M.,Wlodawer, A. Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities. J.Mol.Biol. 2002 317 119 130 1IJJ 11932258 THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION 2001-04-26 2002-04-15 Bubb, M.R.,Govindasamy, L.,Yarmola, E.G.,Vorobiev, S.M.,Almo, S.C.,Somasundaram, T.,Chapman, M.S.,Agbandje-McKenna, M.,McKenna, R. Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution J.Biol.Chem. 2002 277 20999 21006 1L6S 11909869 Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid 2002-03-13 2002-04-17 Jaffe, E.K.,Kervinen, J.,Martins, J.,Stauffer, F.,Neier, R.,Wlodawer, A.,Zdanov, A. Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem. 2002 277 19792 19799 1L6Y 11909869 Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid 2002-03-14 2002-04-17 Jaffe, E.K.,Kervinen, J.,Martins, J.,Stauffer, F.,Neier, R.,Wlodawer, A.,Zdanov, A. Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem. 2002 277 19792 19799 1KTJ 12054778 X-ray Structure Of Der P 2, The Major House Dust Mite Allergen 2002-01-16 2002-05-15 Derewenda, U.,Li, J.,Derewenda, Z.,Dauter, Z.,Mueller, G.A.,Rule, G.S.,Benjamin, D.C. The crystal structure of a major dust mite allergen Der p 2, and its biological implications. J.Mol.Biol. 2002 318 189 197 1L5B 12015150 DOMAIN-SWAPPED CYANOVIRIN-N DIMER 2002-03-06 2002-05-22 Barrientos, L.G.,Louis, J.M.,Botos, I.,Mori, T.,Han, Z.,O'Keefe, B.R.,Boyd, M.R.,Wlodawer, A.,Gronenborn, A.M. The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure 2002 10 673 686 1L9M 11980702 Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation 2002-03-26 2002-05-29 Ahvazi, B.,Kim, H.C.,Kee, S.H.,Nemes, Z.,Steinert, P.M. Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation. EMBO J. 2002 21 2055 2067 1L9N 11980702 Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation 2002-03-26 2002-05-29 Ahvazi, B.,Kim, H.C.,Kee, S.H.,Nemes, Z.,Steinert, P.M. Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation. EMBO J. 2002 21 2055 2067 1L4U 12054870 CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AND PT(II) AT 1.8 ANGSTROM RESOLUTION 2002-03-05 2002-06-12 Gu, Y.,Reshetnikova, L.,Li, Y.,Wu, Y.,Yan, H.,Singh, S.,Ji, X. Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis. J.Mol.Biol. 2002 319 779 789 1L4Y 12054870 CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AT 2.0 ANGSTROM RESOLUTION 2002-03-06 2002-06-12 Gu, Y.,Reshetnikova, L.,Li, Y.,Wu, Y.,Yan, H.,Singh, S.,Ji, X. Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis. J.Mol.Biol. 2002 319 779 789 1L8J 12034704 Crystal Structure of the Endothelial Protein C Receptor and Bound Phospholipid Molecule 2002-03-20 2002-06-26 Oganesyan, V.,Oganesyan, N.,Terzyan, S.,Qu, D.,Dauter, Z.,Esmon, N.L.,Esmon, C.T. The crystal structure of the endothelial protein C receptor and a bound phospholipid. J.Biol.Chem. 2002 277 24851 24854 1JHW Ca2+-binding Mimicry in the Crystal Structure of the Eu3+-Bound Mutant Human Macrophage Capping Protein Cap G 2001-06-28 2002-06-28 Vorobiev, S.M.,Southwick, F.S.,Almo, S.C. Crystal Structure of Mutant Human Macrophage Capping Protein To be Published 0 0 0 0 1LYV High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate. 2002-06-08 2002-07-03 Evdokimov, A.G.,Waugh, D.S.,Routzahn, K.,Tropea, J.,Cherry, S. High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate. To be Published 0 0 0 0 1JA3 12096910 Crystal Structure of the Murine NK Cell Inhibitory Receptor Ly-49I 2001-05-29 2002-07-17 Dimasi, N.,Sawicki, M.W.,Reineck, L.A.,Li, Y.,Natarajan, K.,Margulies, D.H.,Mariuzza, R.A. Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family. J.Mol.Biol. 2002 320 573 585 1KLL 12121648 Molecular basis of mitomycin C resictance in streptomyces: Crystal structures of the MRD protein with and without a drug derivative 2001-12-12 2002-07-19 Martin, T.W.,Dauter, Z.,Devedjiev, Y.,Sheffield, P.,Jelen, F.,He, M.,Sherman, D.H.,Otlewski, J.,Derewenda, Z.S.,Derewenda, U. Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure 2002 10 933 942 1KMZ 12121648 MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE 2001-12-17 2002-07-19 Martin, T.W.,Dauter, Z.,Devedjiev, Y.,Sheffield, P.,Jelen, F.,He, M.,Sherman, D.H.,Otlewski, J.,Derewenda, Z.S.,Derewenda, U. Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure 2002 10 933 942 1FMX 12127998 STRUCTURE OF NATIVE PROTEINASE A IN THE SPACE GROUP P21 2000-08-18 2002-07-31 Gustchina, A.,Li, M.,Phylip, L.H.,Lees, W.E.,Kay, J.,Wlodawer, A. An unusual orientation for Tyr75 in the active site of the aspartic proteinase from Saccharomyces cerevisiae. Biochem.Biophys.Res.Commun. 2002 295 1020 1026 1M8A 12149255 Human MIP-3alpha/CCL20 2002-07-24 2002-07-31 Hoover, D.M.,Boulegue, C.,Yang, D.,Oppenheim, J.J.,Tucker, K.,Lu, W.,Lubkowski, J. The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins J.Biol.Chem. 2002 277 37647 37654 1KP5 12198295 Cyclic Green Fluorescent Protein 2001-12-28 2002-08-28 Hofmann, A.,Iwai, H.,Hess, S.,Pluckthun, A.,Wlodawer, A. Structure of cyclized green fluorescent protein. Acta Crystallogr.,Sect.D 2002 58 1400 1406 1M9Z 12121646 CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN 2002-07-30 2002-09-11 Boesen, C.C.,Radaev, S.,Motyka, S.A.,Patamawenu, A.,Sun, P.D. THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN Structure 2002 10 913 919 1M8W 12202039 CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA 2002-07-26 2002-09-25 Wang, X.,McLachlan, J.,Zamore, P.D.,Hall, T.M.T. MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.) 2002 110 501 512 1M8Y 12202039 CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE2-10 RNA 2002-07-26 2002-09-25 Wang, X.,McLachlan, J.,Zamore, P.D.,Hall, T.M.T. MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.) 2002 110 501 512 1K6K 12205096 Crystal Structure of ClpA, an AAA+ Chaperone-like Regulator of ClpAP protease implication to the functional difference of two ATPase domains 2001-10-16 2002-09-27 Guo, F.,Maurizi, M.R.,Esser, L.,Xia, D. Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease J.Biol.Chem. 2002 277 46743 46752 1KSF 12205096 Crystal Structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease: Structural basis of differences in Function of the Two AAA+ ATPase domains 2002-01-12 2002-09-27 Guo, F.,Maurizi, M.R.,Esser, L.,Xia, D. Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease J.Biol.Chem. 2002 277 46743 46752 1LEE 12454457 CRYSTAL STRUCTURE OF PLASMEPSIN FROM P. FALCIPARUM IN COMPLEX WITH INHIBITOR RS367 2002-04-09 2002-10-09 Asojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Medjahed, D.,Silva, A.M. Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370. Acta Crystallogr.,Sect.D 2002 58 2001 2008 1LF2 12454457 CRYSTAL STRUCTURE OF PLASMEPSIN II FROM P FALCIPARUM IN COMPLEX WITH INHIBITOR RS370 2002-04-10 2002-10-10 Asojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Medjahed, D.,Silva, A.M. Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370. Acta Crystallogr.,Sect.D 2002 58 2001 2008 1LF3 12614616 CRYSTAL STRUCTURE OF PLASMEPSIN II FROM P FALCIPARUM IN COMPLEX WITH INHIBITOR EH58 2002-04-10 2002-10-10 Asojo, O.A.,Gulnik, S.V.,Afonina, E.,Yu, B.,Ellman, J.A.,Haque, T.S.,Silva, A.M. Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum. J.Mol.Biol. 2003 327 173 181 1LF4 12614616 STRUCTURE OF PLASMEPSIN II 2002-04-10 2002-10-10 Asojo, O.A.,Gulnik, S.V.,Afonina, E.,Yu, B.,Ellman, J.A.,Haque, T.S.,Silva, A.M. Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum. J.Mol.Biol. 2003 327 173 181 1M6T 12381319 CRYSTAL STRUCTURE OF B562RIL, A REDESIGNED FOUR HELIX BUNDLE 2002-07-17 2002-11-06 Chu, R.,Takei, J.,Knowlton, J.R.,Andrykovitch, M.,Pei, W.,Kajava, A.V.,Steinbach, P.J.,Ji, X.,Bai, Y. Redesign of a Four-Helix Bundle Protein by Phage Display Coupled with Proteolysis and Structural Characterization by NMR and X-ray Crystallography J.Mol.Biol. 2002 323 253 262 1L1Q 12171925 Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine 2002-02-19 2002-11-27 Shi, W.,Sarver, A.E.,Wang, C.C.,Tanaka, K.S.,Almo, S.C.,Schramm, V.L. Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration. J.Biol.Chem. 2002 277 39981 39988 1L1R 12171925 Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine, Mg2+ and PRPP 2002-02-19 2002-11-27 Shi, W.,Sarver, A.E.,Wang, C.C.,Tanaka, K.S.,Almo, S.C.,Schramm, V.L. Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration. J.Biol.Chem. 2002 277 39981 39988 1LVM 12377789 CATALYTICALLY ACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH PRODUCT 2002-05-28 2002-11-27 Phan, J.,Zdanov, A.,Evdokimov, A.G.,Tropea, J.E.,Peters III, H.K.,Kapust, R.B.,Li, M.,Wlodawer, A.,Waugh, D.S. Structural basis for the substrate specificity of tobacco etch virus protease. J.Biol.Chem. 2002 277 50564 50572 1O7J 12499544 Atomic resolution structure of Erwinia chrysanthemi L-asparaginase 2002-11-07 2002-12-04 Lubkowski, J.,Dauter, M.,Aghaiypour, K.,Wlodawer, A.,Dauter, Z. Atomic Resolution Structure of Erwinia Chrysanthemi L-Asparaginase Acta Crystallogr.,Sect.D 2003 59 84 0 1GQB 12499540 HUMAN MIR-RECEPTOR, REPEAT 11 2001-11-22 2002-12-05 Uson, I.,Schmidt, B.,Von Buelow, R.,Grimme, S.,Von Figura, K.,Dauter, M.,Rajashankar, K.R.,Dauter, Z.,Sheldrick, G.M. Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing Acta Crystallogr.,Sect.D 2003 59 57 0 1KMT 12454455 Crystal structure of RhoGDI Glu(154,155)Ala mutant 2001-12-17 2002-12-11 Mateja, A.,Devedjiev, Y.,Krowarsch, D.,Longenecker, K.,Dauter, Z.,Otlewski, J.,Derewenda, Z.S. The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution. Acta Crystallogr.,Sect.D 2002 58 1983 1991 1MBV 12235156 CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM 2002-08-03 2002-12-11 Guo, F.,Esser, L.,Singh, S.K.,Maurizi, M.R.,Xia, D. Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of AAA+ Chaperone ClpA J.Biol.Chem. 2002 277 46753 46762 1NF5 11419947 Crystal Structure of Lactose Synthase, Complex with Glucose 2002-12-13 2002-12-25 Ramakrishnan, B.,Qasba, P.K. Crystal Structure of Lactose Synthase Reveals a Large Conformational Change in its Catalytic Component, the beta-1,4-galactosyltransferase J.Mol.Biol. 2001 310 205 218 1I1W 12499546 0.89A Ultra high resolution structure of a Thermostable Xylanase from Thermoascus Aurantiacus 2001-02-04 2003-01-07 Natesh, R.,Manikandan, K.,Bhanumoorthy, P.,Viswamitra, M.A.,Ramakumar, S. Thermostable xylanase from Thermoascus aurantiacus at ultrahigh resolution (0.89 A) at 100 K and atomic resolution (1.11 A) at 293 K refined anisotropically to small-molecule accuracy. Acta Crystallogr.,Sect.D 2003 59 105 117 1I1X 12499546 1.11 A ATOMIC RESOLUTION STRUCTURE OF A THERMOSTABLE XYLANASE FROM THERMOASCUS AURANTIACUS 2001-02-04 2003-01-07 Natesh, R.,Manikandan, K.,Bhanumoorthy, P.,Viswamitra, M.A.,Ramakumar, S. Thermostable xylanase from Thermoascus aurantiacus at ultrahigh resolution (0.89 A) at 100 K and atomic resolution (1.11 A) at 293 K refined anisotropically to small-molecule accuracy. Acta Crystallogr.,Sect.D 2003 59 105 117 1NHE 11419947 Crystal structure of Lactose synthase complex with UDP 2002-12-19 2003-01-07 Ramakrishnan, B.,Qasba, P.K. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol. 2001 310 205 218 1NKH 11419947 Crystal structure of Lactose synthase complex with UDP and Manganese 2003-01-03 2003-01-14 Ramakrishnan, B.,Qasba, P.K. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol. 2001 310 205 218 1NLV 12732734 Crystal Structure Of Dictyostelium Discoideum Actin Complexed With Ca ATP And Human Gelsolin Segment 1 2003-01-07 2003-01-21 Vorobiev, S.M.,Strokopytov, B.,Drubin, D.G.,Frieden, C.,Ono, S.,Condeelis, J.,Rubenstein, P.A.,Almo, S.C. The Structure of Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism Proc.Natl.Acad.Sci.USA 2003 100 5760 5765 1NM1 12732734 Crystal Structure of D. Dicsoideum Actin Complexed With Gelsolin Segment 1 and Mg ATP at 1.8 A Resolution 2003-01-08 2003-01-21 Vorobiev, S.M.,Strokopytov, B.,Drubin, D.G.,Frieden, C.,Ono, S.,Condeelis, J.,Rubenstein, P.A.,Almo, S.C. The Structure of Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism Proc.Natl.Acad.Sci.USA 2003 100 5760 5765 1NMM 11485999 beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc 2003-01-10 2003-01-21 Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc. J.Biol.Chem. 2001 276 37665 37671 1MQ2 12517346 Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine and dAMP 2002-09-13 2003-01-28 Krahn, J.M.,Beard, W.A.,Miller, H.,Grollman, A.P.,Wilson, S.H. Structure of DNA Polymerase beta with the Mutagenic DNA Lesion 8-oxodeoxyguanine Reveals Structural Insights into its Coding Potential Structure 2003 11 121 127 1OAD 12777803 Glucose isomerase from Streptomyces rubiginosus in P21212 crystal form 2003-01-08 2003-01-30 Ramagopal, U.A.,Dauter, M.,Dauter, Z. Sad Manganese in Two Crystal Forms of Glucose Isomerase Acta Crystallogr.,Sect.D 2003 59 868 0 1NMD 12732734 Crystal Structure of D. Discoideum Actin-Gelsolin Segment 1 Complex Crystallized In Presence Of Lithium ATP 2003-01-09 2003-02-04 Vorobiev, S.M.,Strokopytov, B.,Drubin, D.G.,Frieden, C.,Ono, S.,Condeelis, J.,Rubenstein, P.A.,Almo, S.C. The Structure Of The Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism Proc.Natl.Acad.Sci.USA 2003 100 5760 5765 1NQI 11419947 crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc 2003-01-21 2003-02-04 Ramakrishnan, B.,Qasba, P.K. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol. 2001 310 205 218 1NWG 11485999 BETA-1,4-GALACTOSYLTRANSFERASE COMPLEX WITH ALPHA-LACTALBUMIN AND N-BUTANOYL-GLUCOAMINE 2003-02-06 2003-02-18 Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. ALPHA-LACTALBUMIN (LA) STIMULATES MILK BETA-1,4-GALACTOSYLTRANSFERASE I (BETA 4GAL-T1) TO TRANSFER GLUCOSE FROM UDP-GLUCOSE TO N-ACETYLGLUCOSAMINE. CRYSTAL STRUCTURE OF BETA 4GAL-T1 X LA COMPLEX WITH UDP-GLC. J.Biol.Chem. 2001 276 37665 37671 1O23 11485999 CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE 2003-01-29 2003-02-25 Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. Alpha-Lactalbumin (La) Stimulates Milk Beta-1,4-Galactosyltransferase I (Beta 4Gal-T1) to Transfer Glucose from Udp-Glucose to N-Acetylglucosamine. Crystal Structure of Beta 4Gal-T1 X La Complex with Udp-Glc. J.Biol.Chem. 2001 276 37665 37671 1N67 12485987 Clumping Factor A from Staphylococcus aureus 2002-11-08 2003-03-04 Deivanayagam, C.C.S.,Wann, E.R.,Chen, W.,Carson, M.,Rajashankar, K.R.,Hook, M.,Narayana, S.V.L. A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A Embo J. 2002 21 6660 6672 1NCN 12606712 the receptor-binding domain of human B7-2 2002-12-05 2003-03-11 Zhang, X.,Schwartz, J.D.,Almo, S.C.,Nathenson, S.G. Crystal Structure of the Receptor-Binding Domain of Human B7-2: Insights into Organization and Signaling Proc.Natl.Acad.Sci.USA 2003 100 2586 2591 1NPP 12600194 CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN P2(1) 2003-01-18 2003-03-11 Knowlton, J.R.,Bubunenko, M.,Andrykovitch, M.,Guo, W.,Routzahn, K.M.,Waugh, D.S.,Court, D.L.,Ji, X. A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by Site-Directed Mutants Biochemistry 2003 42 2275 2281 1NPP 12600194 CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN P2(1) 2003-01-18 2003-03-11 Knowlton, J.R.,Bubunenko, M.,Andrykovitch, M.,Guo, W.,Routzahn, K.M.,Waugh, D.S.,Court, D.L.,Ji, X. A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by Site-Directed Mutants Biochemistry 2003 42 2275 2281 1OQM 11916963 A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine 2003-03-10 2003-03-18 Ramakrishnan, B.,Qasba, P.K. Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity. J.Biol.Chem. 2002 277 20833 20839 1F9H 12578370 CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION 2000-07-10 2003-04-15 Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry 2003 42 1573 1580 1G4C 12578370 CRYSTAL STRUCTURE OF A COMPLEX OF HPPK(R92A) FROM E.COLI WITH MG2+ AT 1.65 ANGSTROM RESOLUTION 2000-10-26 2003-04-15 BLASZCZYK, J.,Li, Y.,SHI, G.,YAN, H.,JI, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry 2003 42 1573 1580 1HQ2 12578370 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION 2000-12-13 2003-04-15 Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry 2003 42 1573 1580 1IM6 12578370 CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION 2001-05-09 2003-04-15 Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry 2003 42 1573 1580 1KBR 12578370 CRYSTAL STRUCTURE OF UNLIGATED HPPK(R92A) FROM E.COLI AT 1.55 ANGSTROM RESOLUTION 2001-11-06 2003-04-15 Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry 2003 42 1573 1580 1ML6 12549910 Crystal Structure of mGSTA2-2 in Complex with the Glutathione Conjugate of Benzo[a]pyrene-7(R),8(S)-Diol-9(S),10(R)-Epoxide 2002-08-30 2003-04-15 Gu, Y.,Xiao, B.,Wargo, H.L.,Bucher, M.H.,Singh, S.V.,Ji, X. Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide Biochemistry 2003 42 917 921 1N99 12679023 CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN 2002-11-22 2003-04-15 Kang, B.S.,Cooper, D.R.,Jelen, F.,Devedjiev, Y.,Derewenda, U.,Dauter, Z.,Otlewski, J.,Derewenda, Z.S. PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties Structure 2003 11 459 468 1NUD 12679341 Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (3 calciums, active form) 2003-01-31 2003-04-22 Ahvazi, B.,Boeshans, K.M.,Idler, W.,Baxa, U.,Steinert, P.M. Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem. 2003 278 23834 23841 1NUF 12679341 Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme 2003-01-31 2003-04-22 Ahvazi, B.,Boeshans, K.M.,Idler, W.,Baxa, U.,Steinert, P.M. Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem. 2003 278 23834 23841 1NUG 12679341 Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form) 2003-01-31 2003-04-22 Ahvazi, B.,Boeshans, K.M.,Idler, W.,Baxa, U.,Steinert, P.M. Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme J.Biol.Chem. 2003 278 23834 23841 1MFW 12692530 STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN 2002-08-13 2003-04-29 Kim, M.H.,Cierpickil, T.,Derewenda, U.,Krowarsch, D.,Feng, Y.,Devedjiev, Y.,Dauter, Z.,Walsh, C.A.,Otlewski, J.,Bushweller, J.H.,Derewenda, Z. The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase Nat.Struct.Biol. 2003 10 324 333 1KMQ 12777804 Crystal Structure of a Constitutively Activated RhoA Mutant (Q63L) 2001-12-17 2003-05-06 Longenecker, K.,Read, P.,Lin, S.K.,Somlyo, A.P.,Nakamoto, R.K.,Derewenda, Z.S. Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution. Acta Crystallogr.,Sect.D 2003 59 876 880 1NWQ 12578822 CRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX 2003-02-06 2003-05-13 Miller, M.,Shuman, J.D.,Sebastian, T.,Dauter, Z.,Johnson, P.F. Structural Basis for DNA Recognition by the Basic Region Leucine Zipper Transcription Factor CCAAT/enhancer Binding Protein Alpha J.Biol.Chem. 2003 278 15178 15184 1ON3 12743028 Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core (with methylmalonyl-coenzyme a and methylmalonic acid bound) 2003-02-26 2003-05-20 Hall, P.R.,Wang, Y.-F.,Rivera-Hainaj, R.E.,Zheng, X.,Pustai-Carey, M.,Carey, P.R.,Yee, V.C. Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core Embo J. 2003 22 2334 2347 1J72 Crystal Structure of Mutant Macrophage Capping Protein (Cap G) with Actin-severing Activity in the Ca2+-Free Form 2001-05-15 2003-06-24 Vorobiev, S.M.,Southwick, F.S.,Storokopytov, B.,Almo, S.C. Crystal Structure of Mutant Human Macrophage Capping Protein To be Published 0 0 0 0 1N00 12787021 Annexin Gh1 from cotton 2002-10-10 2003-06-24 Hofmann, A.,Delmer, D.P.,Wlodawer, A. The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster. Eur.J.Biochem. 2003 270 2557 2564 1NR0 15150269 Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans Homologue Of Yeast Actin Interacting Protein 1 (AIP1). 2003-01-23 2003-07-01 Mohri, K.,Vorobiev, S.M.,Fedorov, A.A.,Almo, S.C.,Ono, S. Identification of Functional Residues on Caenorhabditis elegans Actin-interacting Protein 1 (UNC-78) for Disassembly of Actin Depolymerizing Factor/Cofilin-bound Actin Filaments J.Biol.Chem. 2004 279 31697 31707 1OBX 12842047 Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. 2003-01-31 2003-07-10 Kang, B.S.,Cooper, D.R.,Devedjiev, Y.,Derewenda, U.,Derewenda, Z.S. Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm Structure 2003 11 845 0 1OBY 12842047 Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. 2003-01-31 2003-07-11 Kang, B.S.,Cooper, D.R.,Devedjiev, Y.,Derewenda, U.,Derewenda, Z.S. Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm Structure 2003 11 845 0 1OBZ 12842047 Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha peptide. 2003-01-31 2003-07-11 Kang, B.S.,Cooper, D.R.,Devedjiev, Y.,Derewenda, U.,Derewenda, Z.S. Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm Structure 2003 11 845 0 1NTE 12842047 CRYSTAL STRUCTURE ANALYSIS OF THE SECOND PDZ DOMAIN OF SYNTENIN 2003-01-29 2003-07-15 Kang, B.S.,Cooper, D.R.,Devedjiev, Y.,Derewenda, U.,Derewenda, Z.S. Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm. Structure 2003 11 845 853 1M16 14627732 Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V). 2002-06-17 2003-08-05 Brych, S.R.,Kim, J.,Logan, T.M.,Blaber, M. Accommodation of a highly symmetric core within a symmetric protein superfold Protein Sci. 2003 12 2704 2718 1NR2 12832759 High resolution crystal structures of thymus and activation-regulated chemokine 2003-01-23 2003-08-05 Asojo, O.A.,Boulegue, C.,Hoover, D.M.,Lu, W.,Lubkowski, J. Structures of thymus and activation-regulated chemokine (TARC). Acta Crystallogr.,Sect.D 2003 59 1165 1173 1Q0N 11080626 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE FROM E. COLI WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION 2003-07-16 2003-08-26 Blaszczyk, J.,Shi, G.,Yan, H.,Ji, X. Catalytic Center Assembly of Hppk as Revealed by the Crystal Structure of a Ternary Complex at 1.25 A Resolution Structure 2000 8 1049 1058 1PZT 12927542 CRYSTAL STRUCTURE OF W314A-BETA-1,4-GALACTOSYLTRANSFERASE (B4GAL-T1) CATALYTIC DOMAIN WITHOUT SUBSTRATE 2003-07-14 2003-09-16 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I J.Mol.Biol. 2003 331 1065 1076 1K27 14705926 Crystal Structure of 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with a Transition State Analogue 2001-09-26 2003-09-30 Singh, V.,Shi, W.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A Biochemistry 2004 43 9 18 1PQY 14993676 Crystal structure of formyl-coA transferase yfdW from E. coli 2003-06-19 2003-09-30 Gogos, A.,Gorman, J.,Shapiro, L. Structure of Escherichia coli YfdW, a type III CoA transferase. Acta Crystallogr.,Sect.D 2004 60 507 511 1H4P 14730348 Crystal structure of exo-1,3-beta glucanse from Saccharomyces cerevisiae 2001-05-11 2003-10-02 Taylor, S.C.,Ferguson, A.D.,Bergeron, J.J.M.,Thomas, D.Y. The Er Protein Folding Sensor Udp-Glucose Glycoprotein:Glucosyltransferase Modifies Substrates Distant to Local Changes in Glycoprotein Conformation. Nat.Struct.Mol.Biol. 2004 11 128 0 1NTK 12885240 Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 2003-01-30 2003-10-07 Gao, X.,Wen, X.,Esser, L.,Quinn, B.,Yu, L.,Yu, C.-A.,Xia, D. Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry 2003 42 9067 9080 1NTM 12885240 Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom 2003-01-30 2003-10-07 Gao, X.,Wen, X.,Esser, L.,Quinn, B.,Yu, L.,Yu, C.-A.,Xia, D. Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry 2003 42 9067 9080 1NTZ 12885240 Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone 2003-01-30 2003-10-07 Gao, X.,Wen, X.,Esser, L.,Quinn, B.,Yu, L.,Yu, C.-A.,Xia, D. Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry 2003 42 9067 9080 1PO3 12948487 Crystal structure of ferric citrate transporter FecA in complex with ferric citrate 2003-06-13 2003-11-18 Yue, W.W.,Grizot, S.,Buchanan, S.K. Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA J.Mol.Biol. 2003 332 353 368 1NLU 14733955 Pseudomonas sedolisin (serine-carboxyl proteinase) complexed with two molecules of pseudo-iodotyrostatin 2003-01-07 2004-01-20 Wlodawer, A.,Li, M.,Gustchina, A.,Oyama, H.,Oda, K.,Beyer, B.B.,Clemente, J.,Dunn, B.M. Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: a model for the bi-product complex following cleavage of a peptide substrate. Biochem.Biophys.Res.Commun. 2004 314 638 645 1RRE 14665623 Crystal structure of E.coli Lon proteolytic domain 2003-12-08 2004-02-03 Botos, I.,Melnikov, E.E.,Cherry, S.,Tropea, J.E.,Khalatova, A.G.,Rasulova, F.,Dauter, Z.,Maurizi, M.R.,Rotanova, T.V.,Wlodawer, A.,Gustchina, A. The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site J.Biol.Chem. 2004 279 8140 8148 1RHH 14769016 Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution 2003-11-14 2004-02-24 Darbha, R.,Phogat, S.,Labrijn, A.F.,Shu, Y.,Gu, Y.,Andrykovitch, M.,Zhang, M.Y.,Pantophlet, R.,Martin, L.,Vita, C.,Burton, D.R.,Dimitrov, D.S.,Ji, X. Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope Biochemistry 2004 43 1410 1417 1RTZ 14769023 CRYSTAL STRUCTURE OF E.COLI APO-HPPK(V83G/DEL84-89) AT 1.33 ANGSTROM RESOLUTION 2003-12-10 2004-02-24 Blaszczyk, J.,Li, Y.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry 2004 43 1469 1477 1RU1 14769023 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.40 ANGSTROM RESOLUTION (MONOCLINIC FORM) 2003-12-10 2004-02-24 Blaszczyk, J.,Li, Y.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry 2004 43 1469 1477 1RU2 14769023 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN AT 1.48 ANGSTROM RESOLUTION (ORTHORHOMBIC FORM) 2003-12-10 2004-02-24 Blaszczyk, J.,Li, Y.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry 2004 43 1469 1477 1R6F 14962390 The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague 2003-10-15 2004-03-09 Derewenda, U.,Mateja, A.,Devedjiev, Y.,Routzahn, K.M.,Evdokimov, A.G.,Derewenda, Z.S.,Waugh, D.S. The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague Structure 2004 12 301 306 1OR0 12680762 Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation 2003-03-11 2004-03-11 Kim, J.K.,Yang, I.S.,Rhee, S.,Dauter, Z.,Lee, Y.S.,Park, S.S.,Kim, K.H. Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation Biochemistry 2003 42 4084 4093 1NPU 15030777 CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1 2003-01-20 2004-03-23 Zhang, X.,Schwartz, J.C.,Guo, X.,Bhatia, S.,Cao, E.,Lorenz, M.,Cammer, M.,Chen, L.,Zhang, Z.Y.,Edidin, M.A.,Nathenson, S.G.,Almo, S.C. Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity 2004 20 337 347 1RC5 15016361 CRYSTAL STRUCTURE OF MG(II)-COMPLEX OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.30 ANGSTROM RESOLUTION 2003-11-03 2004-03-30 Blaszczyk, J.,Gan, J.,Tropea, J.E.,Court, D.L.,Waugh, D.S.,Ji, X. Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA. Structure 2004 12 457 466 1SIO 15014068 Structure of Kumamolisin-As complexed with a covalently-bound inhibitor, AcIPF 2004-03-01 2004-03-30 Wlodawer, A.,Li, M.,Gustchina, A.,Tsuruoka, N.,Ashida, M.,Minakata, H.,Oyama, H.,Oda, K.,Nishino, T.,Nakayama, T. Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity J.Biol.Chem. 2004 279 21500 21510 1TCZ 15317025 Crystal structure of a truncated version of the phage lamda protein gpD 2004-05-21 2004-06-15 Chang, C.,Plueckthun, A.,Wlodawer, A. Crystal structure of a truncated version of the phage lambda protein gpD. Proteins 2004 57 866 868 1PXY 15274920 Crystal structure of the actin-crosslinking core of Arabidopsis fimbrin 2003-07-07 2004-06-22 Klein, M.G.,Shi, W.,Ramagopal, U.,Tseng, Y.,Wirtz, D.,Kovar, D.R.,Staiger, C.J.,Almo, S.C. Structure of the actin crosslinking core of fimbrin. Structure 2004 12 999 1013 1ROZ 15100216 Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form 2003-12-02 2004-07-13 Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem. 2004 279 28697 28705 1RQD 15100216 deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form with the inhibitor GC7 bound in the active site 2003-12-04 2004-07-13 Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem. 2004 279 28697 28705 1R6B 15037248 High resolution crystal structure of ClpA 2003-10-15 2004-08-24 Xia, D.,Esser, L.,Singh, S.K.,Guo, F.,Maurizi, M.R. Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone. J.Struct.Biol. 2004 146 166 179 1T89 11297532 CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL) 2004-05-11 2004-09-14 Radaev, S.,Motyka, S.,Fridman, W.-H.,Sautes-Fridman, C.,Sun, P.D. The structure of a human type III Fcgamma receptor in complex with Fc J.Biol.Chem. 2001 276 16469 16477 1VZY 15458638 Crystal structure of the Bacillus subtilis HSP33 2004-05-29 2004-10-06 Janda, I.,Devedjiev, Y.,Derewenda, U.,Dauter, Z.,Bielnicki, J.,Cooper, D.R.,Graf, P.C.,Joachimiak, A.,Jakob, U.,Derewenda, Z.S. The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism. Structure 2004 12 1901 1907 1VL9 16508077 Atomic resolution (0.97A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2 2004-07-15 2004-10-19 Sekar, K.,Rajakannan, V.,Gayathri, D.,Velmurugan, D.,Poi, M.J.,Dauter, M.,Dauter, Z.,Tsai, M.D. Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2. Acta Crystallogr.,Sect.F 2005 61 3 7 1X9Z 15470502 Crystal structure of the MutL C-terminal domain 2004-08-24 2004-10-26 Guarne, A.,Ramon-Maiques, S.,Wolff, E.M.,Ghirlando, R.,Hu, X.,Miller, J.H.,Yang, W. Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair Embo J. 2004 23 4134 4145 1RW1 15102337 YFFB (PA3664) PROTEIN 2003-12-15 2004-11-02 Teplyakov, A.,Pullalarevu, S.,Obmolova, G.,Doseeva, V.,Galkin, A.,Herzberg, O.,Dauter, M.,Dauter, Z.,Gilliland, G.L. Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function. Bmc Struct.Biol. 2004 4 5 5 1TD4 15504410 Crystal structure of VSHP_BPP21 in space group H3 with high resolution. 2004-05-21 2004-11-02 Forrer, P.,Chang, C.,Ott, D.,Wlodawer, A.,Plueckthun, A. Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP. J.Mol.Biol. 2004 344 179 193 1RB0 15016362 CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI HPPK WITH 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.35 ANGSTROM RESOLUTION 2003-10-31 2004-11-09 Blaszczyk, J.,Shi, G.,Li, Y.,Yan, H.,Ji, X. Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. Structure 2004 12 467 475 1TYQ 15505213 Crystal structure of Arp2/3 complex with bound ATP and calcium 2004-07-08 2004-11-09 Nolen, B.J.,Littlefield, R.S.,Pollard, T.D. Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP Proc.Natl.Acad.Sci.Usa 2004 101 15627 15632 1U2V 15505213 Crystal structure of Arp2/3 complex with bound ADP and calcium 2004-07-20 2004-11-09 Nolen, B.J.,Littlefield, R.S.,Pollard, T.D. Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP Proc.Natl.Acad.Sci.Usa 2004 101 15627 15632 1RZN Crystal Structure of Penicillin-binding protein-related factor A from Bacillus Subtilis. 2003-12-24 2004-11-30 Ramagopal, U.A.,Almo, S.C. Crystal Structure of Penicillin-binding protein-related factor A from Bacillus Subtilis. To be Published 0 0 0 0 1TVY 15449940 beta-1,4-galactosyltransferase mutant Met344His (M344H-Gal-T1) complex with UDP-galactose and manganese 2004-06-30 2004-12-14 Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry 2004 43 12513 12522 1TW1 15449940 beta-1,4-galactosyltransferase mutant Met344His (m344H-Gal-T1) complex with UDP-galactose and magnesium 2004-06-30 2004-12-14 Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry 2004 43 12513 12522 1XCG 15530360 Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF 2004-09-01 2004-12-14 Derewenda, U.,Oleksy, A.,Stevenson, A.S.,Korczynska, J.,Dauter, Z.,Somlyo, A.P.,Otlewski, J.,Somlyo, A.V.,Derewenda, Z.S. The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle Structure 2004 12 1955 1965 1XCG 15530360 Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF 2004-09-01 2004-12-14 Derewenda, U.,Oleksy, A.,Stevenson, A.S.,Korczynska, J.,Dauter, Z.,Somlyo, A.P.,Otlewski, J.,Somlyo, A.V.,Derewenda, Z.S. The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle Structure 2004 12 1955 1965 1XCG 15530360 Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF 2004-09-01 2004-12-14 Derewenda, U.,Oleksy, A.,Stevenson, A.S.,Korczynska, J.,Dauter, Z.,Somlyo, A.P.,Otlewski, J.,Somlyo, A.V.,Derewenda, Z.S. The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle Structure 2004 12 1955 1965 1S50 15721240 X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution 2004-01-19 2005-02-08 Mayer, M.L. Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron 2005 45 539 552 1S7Y 15721240 Crystal structure of the GluR6 ligand binding core in complex with glutamate at 1.75 A resolution orthorhombic form 2004-01-30 2005-02-08 Mayer, M.L. Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron 2005 45 539 552 1S9T 15721240 Crystal structure of the GLUR6 ligand binding core in complex with quisqualate at 1.8A resolution 2004-02-05 2005-02-08 Mayer, M.L. Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron 2005 45 539 552 1R6C 15037248 High resolution structure of ClpN 2003-10-15 2005-02-15 Xia, D.,Esser, L.,Singh, S.K.,Guo, F.,Maurizi, M.R. Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone J.Struct.Biol. 2004 146 166 179 1R6O 15037248 ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS 2003-10-15 2005-02-15 Xia, D.,Esser, L.,Singh, S.K.,Guo, F.,Maurizi, M.R. Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone J.Struct.Biol. 2004 146 166 179 1SD3 15721240 Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution 2004-02-12 2005-02-15 Mayer, M.L. Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron 2005 45 539 552 1XDF 15608381 Crystal structure of pathogenesis-related protein LlPR-10.2A from yellow lupine 2004-09-06 2005-02-15 Pasternak, O.,Biesiadka, J.,Dolot, R.,Handschuh, L.,Bujacz, G.,Sikorski, M.M.,Jaskolski, M. Structure of a yellow lupin pathogenesis-related PR-10 protein belonging to a novel subclass. Acta Crystallogr.,Sect.D 2005 61 99 107 1Y7M 16287140 Crystal Structure of the B. subtilis YkuD protein at 2 A resolution 2004-12-09 2005-03-01 Bielnicki, J.,Devedjiev, Y.,Derewenda, U.,Dauter, Z.,Joachimiak, A.,Derewenda, Z.S. B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins 2006 62 144 151 1YY7 15735307 Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor 2005-02-23 2005-03-01 Hansen, A.-M.,Gu, Y.,Li, M.,Andrykovitch, M.,Waugh, D.S.,Jin, D.J.,Ji, X. Structural basis for the function of stringent starvation protein A as a transcription factor J.Biol.Chem. 2005 280 17380 17391 1TG6 15522782 Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP 2004-05-28 2005-03-22 Kang, S.G.,Maurizi, M.R.,Thompson, M.,Mueser, T.,Ahvazi, B. Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP J.Struct.Biol. 2004 148 338 352 1YRO 15736931 Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn 2005-02-04 2005-03-22 Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I Biochemistry 2005 44 3202 3210 1YY8 15837620 Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225 2005-02-24 2005-04-26 Li, S.,Schmitz, K.R.,Jeffrey, P.D.,Wiltzius, J.J.W.,Kussie, P.,Ferguson, K.M. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell 2005 7 301 311 1XRX 15933720 Crystal structure of a DNA-binding protein 2004-10-16 2005-05-10 Guarne, A.,Brendler, T.,Zhao, Q.,Ghirlando, R.,Austin, S.,Yang, W. Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization. Embo J. 2005 24 1502 1511 1Z21 15930010 Crystal structure of the core domain of Yersinia pestis virulence factor YopR 2005-03-07 2005-06-07 Schubot, F.D.,Cherry, S.,Austin, B.P.,Tropea, J.E.,Waugh, D.S. Crystal structure of the protease-resistant core domain of Yersinia pestis virulence factor YopR. Protein Sci. 2005 14 1679 1683 1ZB1 15935782 Structure basis for endosomal targeting by the Bro1 domain 2005-04-07 2005-06-14 Kim, J.,Sitaraman, S.,Hierro, A.,Beach, B.M.,Odorizzi, G.,Hurley, J.H. Structural basis for endosomal targeting by the Bro1 domain. Dev.Cell 2005 8 937 947 1TMJ 15952765 Crystal structure of E.coli apo-HPPK(W89A) at 1.45 Angstrom resolution 2004-06-10 2005-06-21 Li, Y.,Blaszczyk, J.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies. Biochemistry 2005 44 8590 8599 1TMM 15952765 Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin 2004-06-10 2005-06-21 Li, Y.,Blaszczyk, J.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies. Biochemistry 2005 44 8590 8599 1HH3 Decaplanin first P21-Form 2000-12-19 2005-07-11 Lehmann, C.,Debreczeni, J.E.,Bunkoczi, G.,Dauter, M.,Dauter, Z.,Vertesy, L.,Sheldrick, G.M. Structures of Four Crystal Forms of Decaplanin Helv.Chim.Acta 2003 86 1478 0 1HHA Decaplanin first P6122-Form 2000-12-22 2005-07-11 Lehmann, C.,Debreczeni, J.E.,Bunkoczi, G.,Dauter, M.,Dauter, Z.,Vertesy, L.,Sheldrick, G.M. Structures of Four Crystal Forms of Decaplanin Helv.Chim.Acta 2003 86 1478 0 1ZV1 16049008 Crystal structure of the dimerization domain of doublesex protein from D. melanogaster 2005-06-01 2005-08-09 Bayrer, J.R.,Zhang, W.,Weiss, M.A. Dimerization of doublesex is mediated by a cryptic ubiquitin-associated domain fold: implications for sex-specific gene regulation J.Biol.Chem. 2005 280 32989 32996 1X3E 16041080 Crystal structure of the single-stranded DNA-binding protein from Mycobacterium smegmatis 2005-05-04 2005-08-15 Saikrishnan, K.,Manjunath, G.P.,Singh, P.,Jeyakanthan, J.,Dauter, Z.,Sekar, K.,Muniyappa, K.,Vijayan, M. Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. Acta Crystallogr.,Sect.D 2005 61 1140 1148 1TBU Crystal structure of N-terminal domain of yeast peroxisomal thioesterase-1 2004-05-20 2005-10-04 Devedjiev, Y.D.,Li, J.,Derewenda, U.,Derewenda, Z.S. Crystal structure of N-terminal domain of yeast peroxisomal thioesterase-1 To be Published 0 0 0 0 1WQ6 16616331 The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity 2004-09-23 2005-10-04 Liu, Y.,Cheney, M.D.,Gaudet, J.J.,Chruszcz, M.,Lukasik, S.M.,Sugiyama, D.,Lary, J.,Cole, J.,Dauter, Z.,Minor, W.,Speck, N.A.,Bushweller, J.H. The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Cancer Cell 2006 9 249 260 2AE7 16157350 Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with Pentasaccharide 2005-07-21 2005-10-04 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol. 2005 353 53 67 2AEC 16157350 Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,6-Man-beta-OR 2005-07-22 2005-10-04 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol. 2005 353 53 67 2AES 16157350 Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,3-Man-beta-OR 2005-07-23 2005-10-04 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol. 2005 353 53 67 2AGD 16157350 Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I(M340H-B4Gal-T1) in Complex with GlcNAc-beta1,4-Man-alpha1,3-Man-beta-OR 2005-07-26 2005-10-04 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol. 2005 353 53 67 2AH9 16157350 Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with Chitotriose 2005-07-27 2005-10-04 Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol. 2005 353 53 67 1SQQ 15312779 Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) 2004-03-19 2005-10-25 Esser, L.,Quinn, B.,Li, Y.F.,Zhang, M.,Elberry, M.,Yu, L.,Yu, C.A.,Xia, D. Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol. 2004 341 281 302 2BAX 16508077 Atomic Resolution Structure of the Double Mutant (K53,56M) of Bovine Pancreatic Phospholipase A2 2005-10-15 2005-10-25 Sekar, K.,Rajakannan, V.,Gayathri, D.,Velmurugan, D.,Poi, M.J.,Dauter, M.,Dauter, Z.,Tsai, M.D. Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2. Acta Crystallogr.,Sect.F 2005 61 3 7 2FYC 16497331 Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase-I in complex with alpha-lactalbumin, Ca and UDP-galactose 2006-02-07 2006-03-14 Ramakrishnan, B.,Ramasamy, V.,Qasba, P.K. Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol. 2006 357 1619 1633 2FYD 16497331 catalytic domain of bovine beta 1, 4-galactosyltransferase in complex with alpha-lactalbumin, glucose, Mn, and UDP-N-acetylgalactosamine 2006-02-07 2006-03-14 Ramakrishnan, B.,Ramasamy, V.,Qasba, P.K. Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol. 2006 357 1619 1633 1W9E 16533050 Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide 2004-10-09 2006-03-22 Grembecka, J.,Cierpicki, T.,Devedjiev, Y.,Derewenda, U.,Kang, B.S.,Bushweller, J.H.,Derewenda, Z.S. The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry 2006 45 3674 0 1W9O 16533050 Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide 2004-10-15 2006-03-22 Grembecka, J.,Cierpicki, T.,Devedjiev, Y.,Derewenda, U.,Kang, B.S.,Bushweller, J.H.,Derewenda, Z.S. The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry 2006 45 3674 0 2FZS 16682229 Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site 2006-02-10 2006-05-23 Szyk, A.,Maurizi, M.R. Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site. J.Struct.Biol. 2006 156 165 174 1ZVM Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase 2005-06-02 2006-06-06 Shi, W.,Yang, T.,Almo, S.C.,Schramm, V.L.,Sauve, A. Crystal structure of human CD38: Cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase To be Published 0 0 0 0 2BCH 16790927 A possible of Second calcium ion in interfacial binding: Atomic and Medium resolution crystal structures of the quadruple mutant of phospholipase A2 2005-10-19 2006-07-04 Sekar, K.,Yogavel, M.,Kanaujia, S.P.,Sharma, A.,Velmurugan, D.,Poi, M.J.,Dauter, Z.,Tsai, M.D. Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A(2). Acta Crystallogr.,Sect.D 2006 62 717 724 2BQQ 16835924 X-ray Structure of the N-terminal Domain of Human Doublecortin 2005-04-27 2006-07-19 Cierpicki, T.,Kim, M.H.,Cooper, D.R.,Derewenda, U.,Bushweller, J.H.,Derewenda, Z.S. The Dc-Module of Doublecortin: Dynamics, Domain Boundaries, and Functional Implications. Proteins 2006 64 874 0 2J85 17336360 B116 of Sulfolobus turreted icosahedral virus (STIV) 2006-10-19 2006-11-02 Larson, E.T.,Eilers, B.J.,Reiter, D.,Ortmann, A.C.,Young, M.J.,Lawrence, C.M. A New DNA Binding Protein Highly Conserved in Diverse Crenarchaeal Viruses Virology 2007 363 387 0 2HK7 17649975 Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with mercury at 2.5 angstrom resolution 2006-07-03 2007-06-19 Gan, J.,Wu, Y.,Prabakaran, P.,Gu, Y.,Li, Y.,Andrykovitch, M.,Liu, H.,Gong, Y.,Yan, H.,Ji, X. Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism. Biochemistry 2007 46 9513 9522 2HK8 17649975 Crystal structure of shikimate dehydrogenase from aquifex aeolicus at 2.35 angstrom resolution 2006-07-03 2007-06-19 Gan, J.,Wu, Y.,Prabakaran, P.,Gu, Y.,Li, Y.,Andrykovitch, M.,Liu, H.,Gong, Y.,Yan, H.,Ji, X. Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism. Biochemistry 2007 46 9513 9522 2NM2 17331536 Crystal structure of dihydroneopterin aldolase from S. aureus in complex with (1S,2R)-neopterin at 1.50 Angstrom resolution 2006-10-20 2007-09-04 Blaszczyk, J.,Li, Y.,Gan, J.,Yan, H.,Ji, X. Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase. J.Mol.Biol. 2007 368 161 169 2NM3 17331536 Crystal structure of dihydroneopterin aldolase from S. aureus in complex with (1S,2S)-monapterin at 1.68 angstrom resolution 2006-10-20 2007-09-04 Blaszczyk, J.,Li, Y.,Gan, J.,Yan, H.,Ji, X. Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase. J.Mol.Biol. 2007 368 161 169 2QX0 18007032 Crystal Structure of Yersinia pestis HPPK (Ternary Complex) 2007-08-10 2007-10-23 Blaszczyk, J.,Li, Y.,Cherry, S.,Alexandratos, J.,Wu, Y.,Shaw, G.,Tropea, J.E.,Waugh, D.S.,Yan, H.,Ji, X. Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics. Acta Crystallogr.,Sect.D 2007 63 1169 1177 2QT4 17965185 Atomic-resolution crystal structure of the natural form of Scytovirin 2007-08-01 2007-11-27 Moulaei, T.,Botos, I.,Ziolkowska, N.E.,Bokesch, H.R.,Krumpe, L.R.,McKee, T.C.,O'Keefe, B.R.,Dauter, Z.,Wlodawer, A. Atomic-resolution crystal structure of the antiviral lectin scytovirin. Protein Sci. 2007 16 2756 2760 2O90 25264482 Atomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterin 2006-12-12 2007-12-25 Blaszczyk, J.,Lu, Z.,Li, Y.,Yan, H.,Ji, X. Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase. Cell Biosci 2014 4 52 52 3F9Q 19237752 Re-refinement of uncomplexed plasmepsin II from Plasmodium falciparum. 2008-11-14 2009-03-10 Robbins, A.H.,Dunn, B.M.,Agbandje-McKenna, M.,McKenna, R. Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank. Acta Crystallogr.,Sect.D 2009 65 294 296 3GXZ 12110688 Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9) 2009-04-03 2009-04-14 Botos, I.,O'Keefe, B.R.,Shenoy, S.R.,Cartner, L.K.,Ratner, D.M.,Seeberger, P.H.,Boyd, M.R.,Wlodawer, A. Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides J.Biol.Chem. 2002 277 34336 34342 3GXY 12110688 Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside 2009-04-03 2009-05-05 Botos, I.,O'Keefe, B.R.,Shenoy, S.R.,Cartner, L.K.,Ratner, D.M.,Seeberger, P.H.,Boyd, M.R.,Wlodawer, A. Structures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides J.Biol.Chem. 2002 277 34336 34342 3IEU 19706445 Crystal Structure of ERA in Complex with GDP 2009-07-23 2009-08-25 Tu, C.,Zhou, X.,Tropea, J.E.,Austin, B.P.,Waugh, D.S.,Court, D.L.,Ji, X. Structure of ERA in complex with the 3' end of 16S rRNA: implications for ribosome biogenesis Proc.Natl.Acad.Sci.USA 2009 106 14843 14848 3IP0 12578370 Crystal structure of E. coli HPPK in complex with MgAMPCPP and 6-hydroxymethylpterin/6-carboxypterin 2009-08-15 2009-08-25 Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydroptein pyrophosphokinase: Crystallographic studies Biochemistry 2003 42 1573 1580 3H8J Native T4 RNase H in the absence of divalent metal ions 2009-04-29 2010-05-12 Tomanicek, S.J.,Devos, J.M.,Mueser, T.C. Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH To be Published 0 0 0 0 3HCX Crystal structure of E. coli HPPK(N10A) 2009-05-06 2010-05-19 Blaszczyk, J.,Li, Y.,Ji, X.,Yan, H. Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published 0 0 0 0 3HD1 Crystal structure of E. coli HPPK(N10A) in complex with MgAMPCPP 2009-05-06 2010-05-19 Blaszczyk, J.,Li, Y.,Ji, X.,Yan, H. Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published 0 0 0 0 3HD2 Crystal structure of E. coli HPPK(Q50A) in complex with MgAMPCPP and pterin 2009-05-06 2010-05-19 Blaszczyk, J.,Li, Y.,Ji, X.,Yan, H. Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published 0 0 0 0 3HSD Crystal structure of E. coli HPPK(Y53A) 2009-06-10 2010-06-23 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK. To be Published 0 0 0 0 3HSG Crystal structure of E. coli HPPK(Y53A) in complex with MgAMPCPP 2009-06-10 2010-06-23 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published 0 0 0 0 3HSJ Crystal structure of E. coli HPPK(N55A) 2009-06-10 2010-06-23 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published 0 0 0 0 3HSZ Crystal structure of E. coli HPPK(F123A) 2009-06-11 2010-06-23 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published 0 0 0 0 3HT0 Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP 2009-06-11 2010-06-23 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published 0 0 0 0 3ILI Crystal structure of E. coli HPPK(D95A) 2009-08-07 2010-08-11 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published 0 0 0 0 3ILJ Crystal structure of E. coli HPPK(D95A) in complex with MgAMPCPP 2009-08-07 2010-08-11 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published 0 0 0 0 3ILL Crystal structure of E. coli HPPK(D97A) 2009-08-07 2010-08-11 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published 0 0 0 0 3ILO Crystal structure of E. coli HPPK(D97A) in complex with MgAMPCPP and 6-hydroxymethyl-7,8-dihydropterin 2009-08-07 2010-08-11 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published 0 0 0 0 3KUE Crystal structure of E. coli HPPK(E77A) 2009-11-27 2010-11-24 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Roles of residues E77 and H115 in E. coli HPPK To be Published 0 0 0 0 3KUG Crystal structure of E. coli HPPK(H115A) 2009-11-27 2010-11-24 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Roles of residues E77 and H115 in E. coli HPPK To be Published 0 0 0 0 3KUH Crystal structure of E. coli HPPK(H115A) in complex with AMPCPP and HP 2009-11-27 2010-11-24 Li, Y.,Blaszczyk, J.,Ji, X.,Yan, H. Roles of residues E77 and H115 in E. coli HPPK To be Published 0 0 0 0 4L41 Human Lactose synthase: A 2:1 complex between human alpha-lactalbumin and human beta1,4-galactosyltransferase 2013-06-07 2013-10-02 Ramakrishnan, B.,Qasba, P.K. Crystal Structure of Human Lactose Synthase forms a Novel 1:2 Complex between beta1,4Galactosyltransferase 1 and alpha-Lactalbumin Proteins To be Published 0 0 0 0 6M8W 11747435 PSEUDOMONAS SERINE-CARBOXYL PROTEINASE (SEDOLISIN) COMPLEXED WITH THE INHIBITOR AIAF 2018-08-22 2018-10-24 Wlodawer, A.,Li, M.,Gustchina, A.,Dauter, Z.,Uchida, K.,Oyama, H.,Goldfarb, N.E.,Dunn, B.M.,Oda, K. Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase Biochemistry 2001 40 15602 15611 6M8Y 11747435 PSEUDOMONAS SERINE-CARBOXYL PROTEINASE (SEDOLISIN) COMPLEXED WITH THE INHIBITOR AIPF 2018-08-22 2018-10-24 Wlodawer, A.,Li, M.,Gustchina, A.,Dauter, Z.,Uchida, K.,Oyama, H.,Goldfarb, N.E.,Dunn, B.M.,Oda, K. Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase Biochemistry 2001 40 15602 15611 6M9F 11747435 PSEUDOMONAS SERINE-CARBOXYL PROTEINASE (SEDOLISIN) COMPLEXED WITH THE INHIBITOR Tyrostatin 2018-08-23 2018-10-24 Wlodawer, A.,Li, M.,Gustchina, A.,Dauter, Z.,Uchida, K.,Oyama, H.,Goldfarb, N.E.,Dunn, B.M.,Oda, K. Inhibitor complexes of the Pseudomonas serine-carboxyl proteinase Biochemistry 2001 40 15602 15611