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Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta 2011 1814 1832 1840 3AZT 21839861 Diverse Substrates Recognition Mechanism Revealed by Thermotoga maritima Cel5A Structures in Complex with Cellotetraose 2011-05-30 2011-08-10 Wu, T.H.,Huang, C.H.,Ko, T.P.,Lai, H.L.,Ma, Y.,Chen, C.C.,Cheng, Y.S.,Liu, J.R.,Guo, R.T. Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta 2011 1814 1832 1840 3PW9 21908686 Structural and functional Analysis of Arabidopsis thaliana thylakoid lumen protein AtTLP18.3 2010-12-08 2011-10-26 Wu, H.Y.,Liu, M.S.,Lin, T.P.,Cheng, Y.S. 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J.Bacteriol. 2012 194 6518 0 4I0U 23425532 Improved structure of Thermotoga maritima CorA at 2.7 A resolution 2012-11-19 2013-03-06 Nordin, N.,Guskov, A.,Phua, T.,Sahaf, N.,Xia, Y.,Lu, S.Y.,Eshaghi, H.,Eshaghi, S. Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport. Biochem.J. 2013 451 365 374 4HLY 23435230 The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA 2012-10-17 2013-03-13 Hew, K.,Dahlroth, S.L.,Venkatachalam, R.,Nasertorabi, F.,Lim, B.T.,Cornvik, T.,Nordlund, P. The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor. Nucleic Acids Res. 2013 41 4295 4306 4FKZ Crystal structure of Bacillus subtilis UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP 2012-06-14 2013-05-08 Yang, C.S.,Chen, S.C.,Kuan, S.M.,Chen, Y.R.,Liu, Y.H.,Chen, Y. Crystal structure of Bacillus subtilis UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP To be Published 0 0 0 0 4FWH 23897463 Crystal structure of the Lon-like protease MtaLonC in complex with MG262 2012-07-01 2013-06-26 Liao, J.H.,Ihara, K.,Kuo, C.I.,Huang, K.F.,Wakatsuki, S.,Wu, S.H.,Chang, C.I. Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D 2013 69 1395 1402 4G0U 24038465 Human topoisomerase IIbeta in complex with DNA and amsacrine 2012-07-10 2013-07-17 Wu, C.C.,Li, Y.C.,Wang, Y.R.,Li, T.K.,Chan, N.L. On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs Nucleic Acids Res. 2013 41 10630 10640 4G0V 24038465 Human topoisomerase iibeta in complex with DNA and mitoxantrone 2012-07-10 2013-07-17 Wu, C.C.,Li, Y.C.,Wang, Y.R.,Li, T.K.,Chan, N.L. On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs Nucleic Acids Res. 2013 41 10630 10640 4GIT 24531457 Crystal structure of alpha sub-domain of Lon protease from Brevibacillus thermoruber 2012-08-09 2013-09-11 Lee, A.Y.,Chen, Y.D.,Chang, Y.Y.,Lin, Y.C.,Chang, C.F.,Huang, S.J.,Wu, S.H.,Hsu, C.H. Structural basis for DNA-mediated allosteric regulation facilitated by the AAA(+) module of Lon protease. Acta Crystallogr.,Sect.D 2014 70 218 230 4J3N 24038465 Human Topoisomerase Iibeta in complex with DNA 2013-02-06 2013-10-02 Wu, C.C.,Li, Y.C.,Wang, Y.R.,Li, T.K.,Chan, N.L. On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs Nucleic Acids Res. 2013 41 10630 10640 4BFN 24108499 Crystal Structure of the Starch-Binding Domain from Rhizopus oryzae Glucoamylase in Complex with isomaltotetraose 2013-03-21 2013-10-23 Chu, C.,Li, K.,Lin, S.,Chang, M.D.,Jiang, T.,Sun, Y. Crystal Structures of Starch Binding Domain from Rhizopus Oryzae Glucoamylase in Complex with Isomaltooligosaccharide: Insights Into Polysaccharide Binding Mechanism of Cbm21 Family. Proteins 2014 82 1079 0 4BFO 24108499 Crystal Structure of the Starch-Binding Domain from Rhizopus oryzae Glucoamylase in Complex with isomaltotriose 2013-03-21 2013-10-23 Chu, C.,Li, K.,Lin, S.,Chang, M.D.,Jiang, T.,Sun, Y. Crystal Structures of Starch Binding Domain from Rhizopus Oryzae Glucoamylase in Complex with Isomaltooligosaccharide: Insights Into Polysaccharide Binding Mechanism of Cbm21 Family. Proteins 2014 82 1079 0 4HO2 Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine 2012-10-22 2013-10-23 Chen, T.J.,Chien, W.T.,Lin, C.C.,Wang, W.C. Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine TO BE PUBLISHED 0 0 0 0 4HO8 Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and thymidine 2012-10-22 2013-10-23 Chen, T.J.,Chien, W.T.,Lin, C.C.,Wang, W.C. Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and thymidine TO BE PUBLISHED 0 0 0 0 4HOC Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-N-acetylglucosamine 2012-10-22 2013-10-23 Chen, T.J.,Chien, W.T.,Lin, C.C.,Wang, W.C. Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-N-acetylglucosamine TO BE PUBLISHED 0 0 0 0 4BEI 24340031 V. cholera biofilm scaffolding protein RbmA in complex with 18-crown- 6 2013-03-11 2013-12-18 Maestre-Reyna, M.,Wu, W.,Wang, A.H. Structural Insights Into Rbma, a Biofilm Scaffolding Protein of V. Cholerae. Plos One 2013 8 82458 0 4IUF 24464995 Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA 2013-01-21 2014-01-29 Kuo, P.H.,Chiang, C.H.,Wang, Y.T.,Doudeva, L.G.,Yuan, H.S. The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids. Nucleic Acids Res. 2014 42 4712 4722 4LKX 24457896 Humanized antibody 4B12 Fab complexed with a CemX segment 2013-07-09 2014-01-29 Chu, H.M.,Wright, J.,Chan, Y.H.,Lin, C.J.,Chang, T.W.,Lim, C. Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations. Nat Commun 2014 5 3139 3139 4KDE 24386145 Crystal Structure of the Apo Form of Thermus thermophilus Malate Dehydrogenase 2013-04-25 2014-02-05 Hung, C.H.,Hwang, T.S.,Chang, Y.Y.,Luo, H.R.,Wu, S.P.,Hsu, C.H. Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding. Plos One 2013 8 0 0 4KDF 24386145 Crystal Structure of Thermus thermophilus Malate Dehydrogenase in Complex with NAD 2013-04-25 2014-02-05 Hung, C.H.,Hwang, T.S.,Chang, Y.Y.,Luo, H.R.,Wu, S.P.,Hsu, C.H. Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding. Plos One 2013 8 0 0 4M0W 24531491 Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin 2013-08-02 2014-02-12 Chou, C.-Y.,Lai, H.-Y.,Chen, H.-Y.,Cheng, S.-C.,Cheng, K.-W.,Chou, Y.-W. Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease Acta Crystallogr.,Sect.D 2014 70 572 581 3WQK 24475925 Crystal structure of Rv3378c with PO4 2014-01-28 2014-02-19 Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc. 2014 136 2892 2896 3WQL 24475925 Crystal structure of Rv3378c with Mg2+ and PPi 2014-01-28 2014-02-19 Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc. 2014 136 2892 2896 3WQM 24475925 Crystal structure of Rv3378c with inhibitor BPH-629 2014-01-28 2014-02-26 Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc. 2014 136 2892 2896 3WQN 24475925 Crystal structure of Rv3378c_Y51F with TPP 2014-01-28 2014-02-26 Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc. 2014 136 2892 2896 4KT8 24475925 The complex structure of Rv3378c-Y51FY90F with substrate, TPP 2013-05-20 2014-02-26 Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc. 2014 136 2892 2896 4JIS Crystal structure of ribitol 5-phosphate cytidylyltransferase (TarI) from Bacillus subtilis 2013-03-06 2014-03-12 Yang, C.S.,Chen, S.C.,Chen, Y.R.,Kuan, S.M.,Liu, Y.H.,Chen, Y. Crystal structure of ribitol 5-phosphate cytidylyltransferase (TarI) from Bacillus subtilis To be Published 0 0 0 0 4MHN 24598748 Crystal structure of a glutaminyl cyclase from Ixodes scapularis 2013-08-30 2014-03-12 Huang, K.F.,Hsu, H.L.,Karim, S.,Wang, A.H. Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D 2014 70 789 801 4MHP 24598748 Crystal structure of apo-form of glutaminyl cyclase from Ixodes scapularis 2013-08-30 2014-03-12 Huang, K.F.,Hsu, H.L.,Karim, S.,Wang, A.H. Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor binding. Acta Crystallogr.,Sect.D 2014 70 789 801 4K7A Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil 2013-04-16 2014-04-16 Liu, J.S.,Hsu, C.L.,Wu, W.G. Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil To be Published 0 0 0 0 4NEQ 24470206 The structure of UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii 2013-10-29 2014-04-23 Chen, S.C.,Huang, C.H.,Yang, C.S.,Liu, J.S.,Kuan, S.M.,Chen, Y. Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc. Proteins 2014 82 1519 1526 4KIG 24914966 Crystal structure of methyltransferase from Streptomyces hygroscopicus complexed with 4-hydroxyphenylpyruvic acid 2013-05-02 2014-05-07 Zou, X.W.,Liu, Y.C.,Hsu, N.S.,Huang, C.J.,Lyu, S.Y.,Chan, H.C.,Chang, C.Y.,Yeh, H.W.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D 2014 70 1549 1560 4L7Q 24028568 Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish 2013-06-14 2014-05-14 Chuankhayan, P.,Kao, T.-T.,Lin, C.-C.,Guan, H.-H.,Nakagawa, A.,Fu, T.-F.,Chen, C.-J. Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem. 2013 56 7625 7635 4L8F 24028568 Crystal structure of gamma-glutamyl hydrolase (C108A) complex with MTX 2013-06-17 2014-05-14 Chuankhayan, P.,Kao, T.-T.,Lin, C.-C.,Guan, H.-H.,Nakagawa, A.,Fu, T.-F.,Chen, C.-J. Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem. 2013 56 7625 7635 4OCO 24816108 N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc-1-phosphate 2014-01-09 2014-05-14 Wang, K.C.,Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Wu, C.J.,Li, T.L. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr.,Sect.D 2014 70 1401 1410 4OCP 24816108 N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc-1-phosphate and ADP 2014-01-09 2014-05-14 Wang, K.C.,Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Wu, C.J.,Li, T.L. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr.,Sect.D 2014 70 1401 1410 4OCQ 24816108 N-acetylhexosamine 1-phosphate kinase in complex with GalNAc 2014-01-09 2014-05-14 Wang, K.C.,Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Wu, C.J.,Li, T.L. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr.,Sect.D 2014 70 1401 1410 4OCU 24816108 N-acetylhexosamine 1-phosphate kinase_ATCC15697 in complex with GlcNAc 2014-01-09 2014-05-14 Wang, K.C.,Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Wu, C.J.,Li, T.L. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr.,Sect.D 2014 70 1401 1410 4KZN crystal structure of human VEGF-A receptor binding domain 2013-05-30 2014-06-04 Shen, S.T.,Huang, P.T.,Shuau, Y.S.,Lee, Y.M.,Chen, Y.J.,Liaw, Y.C.,Lou, K.L. Structural Basis for the Bivalent Glycosylated Human VEGF-A121 and VEGF-A165 in recruiment of Receptor and Co-receptor to be published 0 0 0 0 3WC9 24789335 The complex structure of HsSQS wtih ligand, FSPP 2013-05-26 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCA 24789335 The complex structure of TcSQS with ligand, FSPP 2013-05-26 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCB 24789335 The complex structure of TcSQS with ligand, BPH1237 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCC 24789335 The complex structure of TcSQS with ligand, E5700 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCD 24789335 The complex structure of HsSQS wtih ligand, WC-9 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCE 24789335 The complex structure of TcSQS with ligand, ER119884 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCF 24789335 The complex structure of HsSQS wtih ligand,BPH1218 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCG 24789335 The complex structure of TcSQS with ligand, BPH1344 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCH 24789335 The complex structure of HsSQS wtih ligand BPH1237 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCI 24789335 The complex structure of HsSQS wtih ligand,BPH1325 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCJ 24789335 The complex structure of HsSQS wtih ligand,E5700 2013-05-27 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCL 24789335 The complex structure of HsSQS wtih ligand,BPH1344 2013-05-28 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 3WCM 24789335 The complex structure of HsSQS wtih ligand, ER119884 2013-05-28 2014-06-18 Shang, N.,Li, Q.,Ko, T.P.,Chan, H.C.,Li, J.,Zheng, Y.,Huang, C.H.,Ren, F.,Chen, C.C.,Zhu, Z.,Galizzi, M.,Li, Z.H.,Rodrigues-Poveda, C.A.,Gonzalez-Pacanowska, D.,Veiga-Santos, P.,de Carvalho, T.M.,de Souza, W.,Urbina, J.A.,Wang, A.H.,Docampo, R.,Li, K.,Liu, Y.L.,Oldfield, E.,Guo, R.T. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog. 2014 10 0 0 4M23 24505011 Crystal structure of non-heme iron oxygenase OrfP 2013-08-05 2014-06-18 Chang, C.Y.,Lyu, S.Y.,Liu, Y.C.,Hsu, N.S.,Wu, C.C.,Tang, C.F.,Lin, K.H.,Ho, J.Y.,Wu, C.J.,Tsai, M.D.,Li, T.L. Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. 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Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol 2014 8 1575 1587 4MFK 25095906 The crystal structure of acyltransferase in complex with decanoyl-CoA 2013-08-28 2014-09-03 Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Huang, C.J.,Chiu, Y.H.,Huang, C.M.,Hsu, N.S.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc. 2014 136 10989 10995 4MFZ 25095906 The crystal structure of acyltransferase in complex with decanoyl-CoA 2013-08-28 2014-09-03 Lyu, S.Y.,Liu, Y.C.,Chang, C.Y.,Huang, C.J.,Chiu, Y.H.,Huang, C.M.,Hsu, N.S.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. 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Enzyme.Microb.Technol. 2015 71 1 7 4XAL 26068188 Crystal structure of the conserved core domain of VP22 from HSV-1 2014-12-15 2015-06-24 Hew, K.,Dahlroth, S.L.,Pan, L.X.,Cornvik, T.,Nordlund, P. VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamilies. J.Gen.Virol. 2015 96 1436 1445 4U88 Structure of the DNA-Binding Domain of the Response Regulator SaeR from Staphylococcus aureus 2014-08-01 2015-08-12 Liu, J.S.,Huang, C.H.,Yang, C.S.,Chen, S.C.,Chen, Y. Structure of the DNA-Binding Domain of the Response Regulator SaeR from Staphylococcus aureus To Be Published 0 0 0 0 3X0T 26261348 Crystal structure of PirA 2014-10-22 2015-08-26 Lee, C.T.,Chen, I.T.,Yang, Y.T.,Ko, T.P.,Huang, Y.T.,Huang, J.Y.,Huang, M.F.,Lin, S.J.,Chen, C.Y.,Lin, S.S.,Lin, S.S.,Lightner, D.V.,Wang, H.C.,Wang, A.H.,Wang, H.C.,Hor, L.I.,Lo, C.F. 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J.Mol.Biol. 2021 433 167116 167116 7V37 34977900 Crystal structure of apo-NP exonuclease 2021-08-10 2021-12-15 Huang, K.W.,Chen, J.W.,Hua, T.Y.,Chu, Y.Y.,Chiu, T.Y.,Liu, J.Y.,Tu, C.I.,Hsu, K.C.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y. Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au 2021 1 2315 2327 7VUM 35054774 Crystal structure of SSB complexed with que 2021-11-03 2022-03-09 Lin, E.S.,Luo, R.H.,Huang, C.Y. A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity. Int J Mol Sci 2022 23 0 0 7F25 35457218 Crystal structure of SSB from Salmonella enterica serovar Typhimurium LT2. 2021-06-10 2022-05-04 Lin, E.S.,Huang, Y.H.,Luo, R.H.,Basharat, Z.,Huang, C.Y. Crystal Structure of an SSB Protein from Salmonella enterica and Its Inhibition by Flavanonol Taxifolin. Int J Mol Sci 2022 23 0 0 7WWW Crystal Structure of Moonlighting GAPDH protein of Lactobacillus gasseri 2022-02-14 2023-02-22 Chen, P.C.,Hsieh, M.H.,Kuo, W.S.,Wu, L.S.H.,Kao, H.F.,Liu, L.F.,Liu, Z.G.,Jeng, W.Y.,Wang, J.Y. Moonlighting GAPDH protein of Lactobacillus gasseri attenuates allergic asthma via immunometabolism change in macrophages To Be Published 0 0 0 0 7X41 Crystal structure of chlorotoxin, a glioma specific scorpion toxin 2022-03-01 2023-03-08 Chang, Y.T. Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent To Be Published 0 0 0 0 7X44 Crystal structure of chlorotoxin mutant - Q11N 2022-03-01 2023-03-08 Chang, Y.T. Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent To Be Published 0 0 0 0 7X4Z Crystal structure of Rhodostomin ARGDWP mutant 2022-03-03 2023-03-08 Chang, Y.T.,Chuang, W.J. Crystal structure of Rhodostomin ARGDWP mutant To be published 0 0 0 0 7Y4B Crystal structure of DUSP10 mutant_D59A 2022-06-14 2023-06-21 Hu, I.C.,Lyu, P.C. Crystal structure of DUSP10 mutant_D59A To Be Published 0 0 0 0 8J3M 38034805 Structure of GH1 Br2 beta-glucosidase from bovine rumen metagenome 2023-04-17 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8J3M 38034805 Structure of GH1 Br2 beta-glucosidase from bovine rumen metagenome 2023-04-17 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8J5L 38034805 Structure of GH1 Br2 beta-glucosidase E163Q mutant from bovine rumen metagenome 2023-04-23 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8J5L 38034805 Structure of GH1 Br2 beta-glucosidase E163Q mutant from bovine rumen metagenome 2023-04-23 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8J5M 38034805 Structure of GH1 Br2 beta-glucosidase E350G mutant from bovine rumen metagenome 2023-04-23 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8J5M 38034805 Structure of GH1 Br2 beta-glucosidase E350G mutant from bovine rumen metagenome 2023-04-23 2023-11-22 Kaenying, W.,Tagami, T.,Suwan, E.,Pitsanuwong, C.,Chomngam, S.,Okuyama, M.,Kongsaeree, P.,Kimura, A.,Kongsaeree, P.T. Structural and mutational analysis of glycoside hydrolase family 1 Br2 beta-glucosidase derived from bovine rumen metagenome. Heliyon 2023 9 0 0 8WQ9 38056157 Crystal structure of dihydropyrimidinase complexed with gamma-aminobutyric acid 2023-10-11 2024-04-03 Huang, Y.H.,Huang, C.Y. The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter gamma-aminobutyric acid (GABA). Biochem.Biophys.Res.Commun. 2024 692 149351 149351