PDB_ID	PUBMED_CID	STRUCTURE TITLE	DEPOSITION DATE	RELEASE DATE	AUTHORS	CITATION TITLE	JOURNAL	YEAR	VOLUME	FIRST PAGE	LAST PAGE
1KUG	12071970	Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW	2002-01-22	2002-07-10	Huang, K.F.,Chiou, S.H.,Ko, T.P.,Wang, A.H.	Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.	Eur.J.Biochem.	2002	269	3047	3056	
1KUK	12071970	Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW.	2002-01-22	2002-07-10	Huang, K.F.,Chiou, S.H.,Ko, T.P.,Wang, A.H.	Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.	Eur.J.Biochem.	2002	269	3047	3056	
1MZ8	12441392	CRYSTAL STRUCTURES OF THE NUCLEASE DOMAIN OF COLE7/IM7 IN COMPLEX WITH A PHOSPHATE ION AND A ZINC ION	2002-10-07	2002-12-23	Sui, M.J.,Tsai, L.C.,Hsia, K.C.,Doudeva, L.G.,Ku, W.Y.,Han, G.W.,Yuan, H.S.	Metal ions and phosphate binding in the H-N-H motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions	PROTEIN SCI.	2002	11	2947	2957	
1NB2	12713952	Crystal Structure of Nucleoside Diphosphate Kinase from Bacillus Halodenitrificans	2002-12-02	2003-05-06	Chen, C.-J.,Liu, M.-Y.,Chang, T.,Chang, W.-C.,Wang, B.-C.,Le Gall, J.	Crystal structure of a nucleoside diphosphate kinase from Bacillus halodenitrificans: coexpression of its activity with a Mn-superoxide dismutase.	J.Struct.Biol.	2003	142	247	255	
1J00	12842470	E. coli Thioesterase I/Protease I/Lysophospholipase L1 in complexed with diethyl phosphono moiety	2002-10-18	2003-07-08	Lo, Y.-C.,Lin, S.-C.,Shaw, J.-F.,Liaw, Y.-C.	Crystal Structure of Escherichia coli Thioesterase I/Protease I/Lysophospholipase L1: Consensus Sequence Blocks Constitute the Catalytic Center of SGNH-hydrolases through a Conserved Hydrogen Bond Network	J.Mol.Biol.	2003	330	539	551	
1JRL	12842470	Crystal structure of E. coli Lysophospholiase L1/Acyl-CoA Thioesterase I/Protease I L109P mutant	2001-08-14	2003-07-08	Lo, Y.-C.,Lin, S.-C.,Shaw, J.-F.,Liaw, Y.-C.	Crystal Structure of Escherichia coli Thioesterase I/Protease I/Lysophospholipase L1: Consensus Sequence Blocks Constitute the Catalytic Center of SGNH-hydrolases through a Conserved Hydrogen Bond Network	J.Mol.Biol.	2003	330	539	551	
1UDV	12837780	Crystal structure of the hyperthermophilic archaeal dna-binding protein Sso10b2 at 1.85 A	2003-05-07	2003-08-05	Chou, C.C.,Lin, T.W.,Chen, C.Y.,Wang, A.H.J.	Crystal structure of the hyperthermophilic archaeal DNA-binding protein Sso10b2 at a resolution of 1.85 Angstroms	J.BACTERIOL.	2003	185	4066	4073	
1UEH	12756244	E. coli undecaprenyl pyrophosphate synthase in complex with Triton X-100, magnesium and sulfate	2003-05-15	2003-08-12	Chang, S.-Y.,Ko, T.-P.,Liang, P.-H.,Wang, A.H.-J.	Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton	J.Biol.Chem.	2003	278	29298	29307	
1V4L	14613481	Crystal structure of a platelet agglutination factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus)	2003-11-14	2003-12-02	Huang, K.F.,Ko, T.P.,Hung, C.C.,Chu, J.,Wang, A.H.,Chiou, S.H.	Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus).	Biochem.J.	2004	378	399	407	
1RJQ	14736882	The crystal structure of the D-aminoacylase mutant D366A	2003-11-20	2004-04-20	Lai, W.L.,Chou, L.Y.,Ting, C.Y.,Kirby, R.,Tsai, Y.C.,Wang, A.H.,Liaw, S.H.	The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.	J.Biol.Chem.	2004	279	13962	13967	
1RJR	14736882	The crystal structure of the D-aminoacylase D366A mutant in complex with 100mM ZnCl2	2003-11-20	2004-04-20	Lai, W.L.,Chou, L.Y.,Ting, C.Y.,Kirby, R.,Tsai, Y.C.,Wang, A.H.,Liaw, S.H.	The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.	J.Biol.Chem.	2004	279	13962	13967	
1RK5	14736882	The D-aminoacylase mutant D366A in complex with 100mM CuCl2	2003-11-20	2004-04-20	Lai, W.L.,Chou, L.Y.,Ting, C.Y.,Kirby, R.,Tsai, Y.C.,Wang, A.H.,Liaw, S.H.	The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.	J.Biol.Chem.	2004	279	13962	13967	
1VG7	15196010	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A/D62A mutant	2004-04-23	2004-05-18	Guo, R.T.,Kuo, C.J.,Ko, T.P.,Chou, C.C.,Liang, P.H.,Wang, A.H.-J.	A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products	Biochemistry	2004	43	7678	7686	
1V1Q	15383524	Crystal structure of PriB- a primosomal DNA replication protein of Escherichia coli	2004-04-22	2004-10-25	Liu, J.-H.,Chang, T.-W.,Huang, C.-Y.,Chen, S.-U.,Wu, H.-N.,Chang, M.-C.,Hsiao, C.-D.	Crystal Structure of Prib- a Primosomal DNA Replication Protein of Escherichia Coli	J.Biol.Chem.	2004	279	50465	0	
1U26	15530366	Crystal structure of Selenomonas ruminantium phytase complexed with persulfated phytate	2004-07-16	2004-11-09	Chu, H.M.,Guo, R.T.,Lin, T.W.,Chou, C.C.,Shr, H.L.,Lai, H.L.,Tang, T.Y.,Cheng, K.J.,Selinger, B.L.,Wang, A.H.-J.	Structures of Selenomonas ruminantium Phytase in Complex with Persulfated Phytate; DSP Phytase Fold and Mechanism for Sequential Substrate Hydrolysis	STRUCTURE	2004	12	2015	2024	
1WM3	15479240	Crystal structure of human SUMO-2 protein	2004-07-02	2004-11-30	Huang, W.-C.,Ko, T.-P.,Li, S.S.-L.,Wang, A.H.-J.	Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins	Eur.J.Biochem.	2004	271	4114	4122	
1V2G	15697222	The L109P mutant of E. coli Thioesterase I/Protease I/Lysophospholipase L1 (TAP) in complexed with octanoic acid	2003-10-15	2004-12-14	Lo, Y.-C.,Lin, S.-C.,Shaw, J.-F.,Liaw, Y.-C.	Substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement	Biochemistry	2005	44	1971	1979	
1XT3	15590643	Structure Basis of Venom Citrate-Dependent Heparin Sulfate-Mediated Cell Surface Retention of Cobra Cardiotoxin A3	2004-10-21	2004-12-14	Lee, S.-C.,Guan, H.-H.,Wang, C.-H.,Huang, W.-N.,Tjong, S.-C.,Chen, C.-J.,Wu, W.-G.	Structural basis of citrate-dependent and heparan sulfate-mediated cell surface retention of cobra cardiotoxin A3	J.Biol.Chem.	2005	280	9567	9577	
1XYI	15653643	Hyperthermophile chromosomal protein Sac7d double mutant Val26Ala/Met29Ala in complex with DNA GCGATCGC	2004-11-10	2005-02-08	Chen, C.-Y.,Ko, T.-P.,Lin, T.-W.,Chou, C.-C.,Chen, C.-J.,Wang, A.H.-J.	Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d	Nucleic Acids Res.	2005	33	430	438	
1PKU	15890279	Crystal Structure of Nucleoside Diphosphate Kinase from Rice	2003-06-06	2005-02-22	Huang, J.Y.,Chang, T.,Chang, C.Y.,Chen, C.J.	Crystal structure of nucleoside diphosphate kinase required for coleoptile elongation in rice (Oryza sativa L.).	J.Struct.Biol.	2005	150	309	318	
1WTO	15653643	Hyperthermophile chromosomal protein SAC7D double mutant V26F/M29F in complex with DNA GCGATCGC	2004-11-29	2005-02-22	Chen, C.-Y.,Ko, T.-P.,Lin, T.-W.,Chou, C.-C.,Chen, C.-J.,Wang, A.H.-J.	Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d	NUCLEIC ACIDS RES.	2005	33	430	438	
1WTV	15653643	Hyperthermophile chromosomal protein SAC7D single mutant M29A in complex with DNA GTAATTAC	2004-11-29	2005-02-22	Chen, C.-Y.,Ko, T.-P.,Lin, T.-W.,Chou, C.-C.,Chen, C.-J.,Wang, A.H.-J.	Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d	NUCLEIC ACIDS RES.	2005	33	430	438	
1VF8	15522777	The Crystal Structure of Ym1 at 1.31 A Resolution	2004-04-09	2005-03-15	Tsai, M.L.,Liaw, S.H.,Chang, N.C.	The crystal structure of Ym1 at 1.31 A resolution	J.Struct.Biol.	2004	148	290	296	
1X06	15788389	Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg, IPP and Fspp	2005-03-15	2005-03-22	Guo, R.T.,Ko, T.P.,Chen, A.P.,Kuo, C.J.,Wang, A.H.,Liang, P.H.	Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.	J.Biol.Chem.	2005	280	20762	20774	
1X08	15788389	Crystal structure of D26A mutant UPPs in complex with Mg, IPP and FsPP	2005-03-15	2005-03-22	Guo, R.T.,Ko, T.P.,Chen, A.P.,Kuo, C.J.,Wang, A.H.,Liang, P.H.	Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.	J.Biol.Chem.	2005	280	20762	20774	
1X09	15788389	Crystal structure of the D26A mutant UPPs in complex with magnesium and isopentenyl pyrophosphate	2005-03-15	2005-03-22	Guo, R.T.,Ko, T.P.,Chen, A.P.,Kuo, C.J.,Wang, A.H.,Liang, P.H.	Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.	J.Biol.Chem.	2005	280	20762	20774	
2BHI	16263708	Crystal structure of Taiwan cobra cardiotoxin A3 complexed with sulfogalactoceramide	2005-01-12	2005-11-28	Wang, C.-H.,Liu, J.-H.,Lee, S.-C.,Hsiao, C.-D.,Wu, W.-G.	Glycosphingolipid-Facilitated Membrane Insertion and Internalization of Cobra Cardiotoxin: The Sulfatide/Cardiotoxin Complex Structure in a Membrane-Like Environment Suggests a Lipid-Dependent Cell-Penetrating Mechanism for Membrane Binding Polypeptides.	J.Biol.Chem.	2006	281	656	0	
1XTA		Crystal Structure of Natrin, a snake venom CRISP from Taiwan cobra (Naja atra)	2004-10-21	2005-12-13	Wang, Y.-L.,Goh, K.-X.,Lee, S.-C.,Huang, W.-N.,Wu, W.-G.,Chen, C.-J.	Structures of snake venom CRISP reveal an action mechanism involving serine protease and ion channel blocking domains	To be Published	0	0	0	0	
2DH4	16554305	Geranylgeranyl pyrophosphate synthase	2006-03-22	2006-04-04	Chang, T.-H.,Guo, R.-T.,Ko, T.-P.,Wang, A.H.,Liang, P.-H.	Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination.	J.Biol.Chem.	2006	281	14991	15000	
2C6Y	16624804	Crystal structure of interleukin enhancer-binding factor 1 bound to DNA	2005-11-15	2006-04-18	Tsai, K.-L.,Huang, C.-Y.,Chang, C.-H.,Sun, Y.-J.,Chuang, W.-J.,Hsiao, C.-D.	Crystal Structure of the Human Foxk1A-DNA Complex and its Implications on the Diverse Binding Specificity of Winged Helix/Forkhead Proteins.	J.Biol.Chem.	2006	281	17400	0	
2G0G	16640330	Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities	2006-02-13	2006-05-16	Lu, I.L.,Huang, C.F.,Peng, Y.H.,Lin, Y.T.,Hsieh, H.P.,Chen, C.T.,Lien, T.W.,Lee, H.J.,Mahindroo, N.,Prakash, E.,Yueh, A.,Chen, H.Y.,Goparaju, C.M.,Chen, X.,Liao, C.C.,Chao, Y.S.,Hsu, J.T.,Wu, S.Y.	Structure-Based Drug Design of a Novel Family of PPARgamma Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities	J.Med.Chem.	2006	49	2703	2712	
2DF7	16677827	Crystal structure of infectious bursal disease virus VP2 subviral particle	2006-02-27	2006-06-27	Lee, C.C.,Ko, T.P.,Chou, C.C.,Yoshimura, M.,Doong, S.R.,Wang, M.Y.,Wang, A.H.	Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity.	J.Struct.Biol.	2006	155	74	86	
2ATH	16366601	Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist	2005-08-25	2006-08-25	Mahindroo, N.,Huang, C.-F.,Peng, Y.-H.,Wang, C.-C.,Liao, C.-C.,Lien, T.-W.,Chittimalla, S.K.,Huang, W.-J.,Chai, C.-H.,Prakash, E.,Chen, C.-P.,Hsu, T.-A.,Peng, C.-H.,Lu, I.-L.,Lee, L.-H.,Chang, Y.-W.,Chen, W.-C.,Chou, Y.-C.,Chen, C.-T.,Goparaju, C.M.V.,Chen, Y.-S.,Lan, S.-J.,Yu, M.-C.,Chen, X.,Chao, Y.-S.,Wu, S.-Y.,Hsieh, H.-P.	Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities	J.Med.Chem.	2005	48	8194	8208	
2GZ9	16913704	Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease	2006-05-11	2006-08-29	Lu, I.L.,Mahindroo, N.,Liang, P.H.,Peng, Y.H.,Kuo, C.J.,Tsai, K.C.,Hsieh, H.P.,Chao, Y.S.,Wu, S.Y.	Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease	J.Med.Chem.	2006	49	5154	5161	
2CCZ	16899446	Crystal structure of E. coli primosomol protein PriB bound to ssDNA	2006-01-19	2006-09-18	Huang, C.-Y.,Hsu, C.-H.,Sun, Y.-J.,Wu, H.-N.,Hsiao, C.-D.	Complexed Crystal Structure of Replication Restart Primsome Protein Prib Reveals a Novel Single-Stranded DNA-Binding Mode.	Nucleic Acids Res.	2006	34	3878	0	
2D2R	18382620	Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase	2005-09-16	2006-09-26	Kuo, C.J.,Guo, R.T.,Lu, I.L.,Liu, H.G.,Wu, S.Y.,Ko, T.P.,Wang, A.H.,Liang, P.H.	Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases.	J.Biomed.Biotechnol.	2008	2008	841312	841312	
2BQY	16988955	Inorganic Pyrophosphatase from the Pathogenic Bacterium Helicobacter pylori-Kinetic and Structural Properties	2005-04-28	2006-10-18	Chao, T.-C.,Huang, H.,Tsai, J.Y.,Huang, C.Y.,Sun, Y.-J.	Kinetic and Structural Properties of Inorganic Pyrophosphatase from the Pathogenic Bacterium Helicobacter Pylori.	Proteins	2006	65	670	0	
2DFL	17329376	Crystal structure of left-handed RadA filament	2006-03-02	2007-01-23	Chen, L.T.,Ko, T.P.,Chang, Y.C.,Lin, K.A.,Chang, C.S.,Wang, A.H.J.,Wang, T.F.	Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins	Nucleic Acids Res.	2007	35	1787	1801	
2J3E	17337454	Dimerization is important for the GTPase activity of chloroplast translocon components atToc33 and psToc159	2006-08-21	2007-03-27	Yeh, Y.,Kesavulu, M.M.,Li, H.,Wu, S.,Sun, Y.,Konozy, E.H.E.,Hsiao, C.	Dimerization is Important for the Gtpase Activity of Chloroplast Translocon Components Attoc33 and Pstoc159.	J.Biol.Chem.	2007	282	13845	0	
2CMG	17357156	Crystal Structure of Spermidine Synthase from Helicobacter Pylori	2006-05-08	2007-05-08	Lu, P.-K.,Tsai, J.-Y.,Chien, H.Y.,Huang, H.,Chu, C.-H.,Sun, Y.-J.	Crystal Structure of Helicobacter Pylori Spermidine Synthase: A Rossmann-Like Fold with a Distinct Active Site	Proteins: Struct., Funct., Bio	2007	67	743	0	
2ZU5	19144641	complex structure of SARS-CoV 3CL protease with TG-0205486	2008-10-12	2009-01-13	Lee, C.C.,Kuo, C.J.,Ko, T.P.,Hsu, M.F.,Tsui, Y.C.,Chang, S.C.,Yang, S.,Chen, S.J.,Chen, H.C.,Hsu, M.C.,Shih, S.R.,Liang, P.H.,Wang, A.H.-J.	Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds	J.Biol.Chem.	2009	284	7646	7655	
2ZY3	19368885	dodecameric L-aspartate beta-decarboxylase	2009-01-13	2009-01-27	Chen, H.-J.,Ko, T.-P.,Lee, C.-Y.,Wang, N.-C.,Wang, A.H.-J.	Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase	Structure	2009	17	517	529	
3SFW		Crystal structure of dihydropyrimidinase from Brevibacillus agri NCHU1002	2011-06-14	2012-06-20	Wang, W.C.,Wu, H.M.	Crystal structure of dihydropyrimidinase from Brevibacillus agri NCHU1002	To be Published	0	0	0	0	
4QNN		Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom	2014-06-18	2015-06-24	Chuang, C.Y.,Ko, T.P.,Wang, A.H.J.,Hou, M.H.	Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom	To be Published	0	0	0	0