PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 1DDZ 10681531 X-RAY STRUCTURE OF A BETA-CARBONIC ANHYDRASE FROM THE RED ALGA, PORPHYRIDIUM PURPUREUM R-1 1999-11-12 2000-03-08 Mitsuhashi, S.,Mizushima, T.,Yamashita, E.,Yamamoto, M.,Kumasaka, T.,Moriyama, H.,Ueki, T.,Miyachi, S.,Tsukihara, T. X-ray structure of beta-carbonic anhydrase from the red alga, Porphyridium purpureum, reveals a novel catalytic site for CO(2) hydration. J.Biol.Chem. 2000 275 5521 5526 1GCJ 10964573 N-TERMINAL FRAGMENT OF IMPORTIN-BETA 2000-07-31 2000-10-18 Lee, S.J.,Imamoto, N.,Sakai, H.,Nakagawa, A.,Kose, S.,Koike, M.,Yamamoto, M.,Kumasaka, T.,Yoneda, Y.,Tsukihara, T. The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport. J.Mol.Biol. 2000 302 251 264 1EWK 11069170 CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 COMPLEXED WITH GLUTAMATE 2000-04-26 2000-12-18 Kunishima, N.,Shimada, Y.,Tsuji, Y.,Sato, T.,Yamamoto, M.,Kumasaka, T.,Nakanishi, S.,Jingami, H.,Morikawa, K. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature 2000 407 971 977 1EE8 10921868 CRYSTAL STRUCTURE OF MUTM (FPG) PROTEIN FROM THERMUS THERMOPHILUS HB8 2000-01-31 2001-01-31 Sugahara, M.,Mikawa, T.,Kumasaka, T.,Yamamoto, M.,Kato, R.,Fukuyama, K.,Inoue, Y.,Kuramitsu, S. Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8. EMBO J. 2000 19 3857 3869 1HJC 11257229 CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER 2001-01-11 2001-03-09 Tahirov, T.H.,Inoue-Bungo, T.,Morii, H.,Fujikawa, A.,Sasaki, M.,Kimura, K.,Shiina, M.,Sato, K.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta Cell(Cambridge,Mass.) 2001 104 755 0 1IO4 11257229 CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER 2001-01-10 2001-03-12 Tahirov, T.H.,Inoue-Bungo, T.,Morii, H.,Fujikawa, A.,Sasaki, M.,Kimura, K.,Shiina, M.,Sato, K.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell(Cambridge,Mass.) 2001 104 755 767 1G12 11223512 ZINC PEPTIDASE FROM GRIFOLA FRONDOSA 2000-10-10 2001-03-14 Hori, T.,Kumasaka, T.,Yamamoto, M.,Nonaka, N.,Tanaka, N.,Hashimoto, Y.,Ueki, U.,Takio, K. Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms. Acta Crystallogr.,Sect.D 2001 57 361 368 1GE6 11223512 ZINC PEPTIDASE FROM GRIFOLA FRONDOSA 2000-10-11 2001-03-14 Hori, T.,Kumasaka, T.,Yamamoto, M.,Nonaka, N.,Tanaka, N.,Hashimoto, Y.,Ueki, U.,Takio, K. Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms. Acta Crystallogr.,Sect.D 2001 57 361 368 1GE7 11223512 ZINC PEPTIDASE FROM GRIFOLA FRONDOSA 2000-10-11 2001-03-14 Hori, T.,Kumasaka, T.,Yamamoto, M.,Nonaka, N.,Tanaka, N.,Hashimoto, Y.,Ueki, U.,Takio, K. Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms. Acta Crystallogr.,Sect.D 2001 57 361 368 1ERZ 10903946 CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES 2000-04-06 2001-04-06 Nakai, T.,Hasegawa, T.,Yamashita, E.,Yamamoto, M.,Kumasaka, T.,Ueki, T.,Nanba, H.,Ikenaka, Y.,Takahashi, S.,Sato, M.,Tsukihara, T. Crystal structure of N-carbamyl-D-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases. Structure Fold.Des. 2000 8 729 737 1H88 11792321 CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX1 2001-01-29 2002-01-28 Tahirov, T.H.,Sato, K.,Ichikawa-Iwata, E.,Sasaki, M.,Inoue-Bungo, T.,Shiina, M.,Kimura, K.,Takata, S.,Fujikawa, A.,Morii, H.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter Cell(Cambridge,Mass.) 2002 108 57 0 1H89 11792321 CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX2 2001-01-30 2002-01-28 Tahirov, T.H.,Sato, K.,Ichikawa-Iwata, E.,Sasaki, M.,Inoue-Bungo, T.,Shiina, M.,Kimura, K.,Takata, S.,Fujikawa, A.,Morii, H.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter Cell(Cambridge,Mass.) 2002 108 57 0 1H8A 11792321 CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX3 2001-01-31 2002-01-28 Tahirov, T.H.,Sato, K.,Ichikawa-Iwata, E.,Sasaki, M.,Inoue-Bungo, T.,Shiina, M.,Kimura, K.,Takata, S.,Fujikawa, A.,Morii, H.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter Cell(Cambridge,Mass.) 2002 108 57 0 1GC0 10965031 CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA 2000-07-06 2002-05-08 Motoshima, H.,Inagaki, K.,Kumasaka, T.,Furuichi, M.,Inoue, H.,Tamura, T.,Esaki, N.,Soda, K.,Tanaka, N.,Yamamoto, M.,Tanaka, H. Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida. J.Biochem. 2000 128 349 354 1GC2 10965031 CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA 2000-07-06 2002-05-08 Motoshima, H.,Inagaki, K.,Kumasaka, T.,Furuichi, M.,Inoue, H.,Tamura, T.,Esaki, N.,Soda, K.,Tanaka, N.,Yamamoto, M.,Tanaka, H. Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida. J.Biochem. 2000 128 349 354 1GC2 10965031 CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA 2000-07-06 2002-05-08 Motoshima, H.,Inagaki, K.,Kumasaka, T.,Furuichi, M.,Inoue, H.,Tamura, T.,Esaki, N.,Soda, K.,Tanaka, N.,Yamamoto, M.,Tanaka, H. Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida. J.Biochem. 2000 128 349 354 1GC2 10965031 CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA 2000-07-06 2002-05-08 Motoshima, H.,Inagaki, K.,Kumasaka, T.,Furuichi, M.,Inoue, H.,Tamura, T.,Esaki, N.,Soda, K.,Tanaka, N.,Yamamoto, M.,Tanaka, H. Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida. J.Biochem. 2000 128 349 354 1IOO 11724536 CRYSTAL STRUCTURE OF NICOTIANA ALATA GEMETOPHYTIC SELF-INCOMPATIBILITY ASSOCIATED SF11-RNASE 2001-03-26 2002-05-08 Ida, K.,Norioka, S.,Yamamoto, M.,Kumasaka, T.,Yamashita, E.,Newbigin, E.,Clarke, A.E.,Sakiyama, F.,Sato, M. The 1.55 A resolution structure of Nicotiana alata S(F11)-RNase associated with gametophytic self-incompatibility. J.Mol.Biol. 2001 314 103 112 1I2H 12054806 CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN 2001-02-09 2002-05-29 Irie, K.,Nakatsu, T.,Mitsuoka, K.,Miyazawa, A.,Sobue, K.,Hiroaki, Y.,Doi, T.,Fujiyoshi, Y.,Kato, H. Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and Own Proline-rich Motif J.Mol.Biol. 2002 318 1117 1126 1H38 12422209 Structure of a T7 RNA polymerase elongation complex at 2.9A resolution 2002-08-24 2002-11-20 Tahirov, T.H.,Temiakov, D.,Anikin, M.,Patlan, V.,Mcallister, W.T.,Vassylyev, D.G.,Yokoyama, S. Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature 2002 420 43 0 1N75 12554668 Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP. 2002-11-12 2003-02-25 Sekine, S.,Nureki, O.,Dubois, D.Y.,Bernier, S.,Chenevert, R.,Lapointe, J.,Vassylyev, D.G.,Yokoyama, S. ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J. 2003 22 676 688 1ODE Crystal Analysis Of Chorismate Mutase From Thermus Thermophilus. 2003-02-18 2003-02-27 Inagaki, E.,Kuramitsu, S.,Yokoyama, S.,Miyano, M.,Tahirov, T.H. The Crystal Structure of Chorismate Mutase from Thermus Thermophilus To be Published 0 0 0 0 1J3N 18453702 Crystal Structure of 3-oxoacyl-(acyl-carrier protein) Synthase II from Thermus thermophilus HB8 2003-02-10 2003-03-11 Bagautdinov, B.,Ukita, Y.,Miyano, M.,Kunishima, N. Structure of 3-oxoacyl-(acyl-carrier protein) synthase II from Thermus thermophilus HB8. Acta Crystallogr.,Sect.F 2008 64 358 366 1GU4 Crystal structure of C/EBPBETA BZIP homodimer bound to a high affinity DNA fragment 2002-01-23 2003-06-26 Tahirov, T.H.,Inoue-Bungo, T.,Sato, K.,Sasaki, M.,Ogata, K. Structural Basis for Flexible Base Recognition by C/Ebpbeta To be Published 0 0 0 0 1GU5 Crystal structure of C/EBPBETA BZIP homodimer bound to a DNA fragment from the MIM-1 promoter 2002-01-24 2003-06-26 Tahirov, T.H.,Inoue-Bungo, T.,Sato, K.,Sasaki, M.,Ogata, K. Structural Basis for Flexible Base Recognition by C/Ebpbeta To be Published 0 0 0 0 1IUK 12832765 The structure of native ID.343 from Thermus thermophilus 2002-03-05 2003-07-15 Wada, T.,Shirouzu, M.,Terada, T.,Ishizuka, Y.,Matsuda, T.,Kigawa, T.,Kuramitsu, S.,Park, S.Y.,Tame, J.R.,Yokoyama, S. Structure of a conserved CoA-binding protein synthesized by a cell-free system. Acta Crystallogr.,Sect.D 2003 59 1213 1218 1UI0 14556741 Crystal Structure Of Uracil-DNA Glycosylase From Thermus Thermophilus HB8 2003-07-14 2003-10-14 Hoseki, J.,Okamoto, A.,Masui, R.,Shibata, T.,Inoue, Y.,Yokoyama, S.,Kuramitsu, S. Crystal Structure of a Family 4 Uracil-DNA Glycosylase from Thermus thermophilus HB8 J.Mol.Biol. 2003 333 515 526 1UI1 14556741 Crystal Structure Of Uracil-DNA Glycosylase From Thermus Thermophilus HB8 2003-07-14 2003-10-14 Hoseki, J.,Okamoto, A.,Masui, R.,Shibata, T.,Inoue, Y.,Yokoyama, S.,Kuramitsu, S. Crystal Structure of a Family 4 Uracil-DNA Glycosylase from Thermus thermophilus HB8 J.Mol.Biol. 2003 333 515 526 1UHN 12871972 The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana 2003-07-07 2003-11-04 Nagae, M.,Nozawa, A.,Koizumi, N.,Sano, H.,Hashimoto, H.,Sato, M.,Shimizu, T. The Crystal Structure of the Novel Calcium-binding Protein AtCBL2 from Arabidopsis thaliana J.Biol.Chem. 2003 278 42240 42246 1Q3Q 14729342 Crystal structure of the chaperonin from Thermococcus strain KS-1 (two-point mutant complexed with AMP-PNP) 2003-07-31 2004-01-27 Shomura, Y.,Yoshida, T.,Iizuka, R.,Maruyama, T.,Yohda, M.,Miki, K. Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol. 2004 335 1265 1278 1J1T Alginate lyase from Alteromonas sp.272 2002-12-14 2004-02-03 Motoshima, H.,Iwatomo, Y.,Watanabe, K.,Oda, T.,Muramatsu, T. Crystal structure of Alginate Lyase from Alteromonas sp.272 To be published 0 0 0 0 1GVJ ETS-1 DNA BINDING AND AUTOINHIBITORY DOMAINS 2002-02-14 2004-02-06 Tahirov, T.H.,Inoue-Bungo, T.,Ogata, K. Crystal Structure of C-Ets-1 DNA-Binding and Autoinhibitory Domains To be Published 0 0 0 0 1UMD 15033367 branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methyl-2-oxopentanoate as an intermediate 2003-09-25 2004-03-30 Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N. Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography J.Mol.Biol. 2004 337 1011 1033 1V9M 15103125 Crystal structure of the C subunit of V-type ATPase from Thermus thermophilus 2004-01-26 2004-05-04 Numoto, N.,Kita, A.,Miki, K. Structure of the C subunit of V-type ATPase from Thermus thermophilus at 1.85 A resolution. Acta Crystallogr.,Sect.D 2004 60 810 815 1UJ4 13679361 Crystal structure of Thermus thermophilus ribose-5-phosphate isomerase 2003-07-26 2004-07-13 Hamada, K.,Ago, H.,Sugahara, M.,Nodake, Y.,Kuramitsu, S.,Miyano, M. Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi) J.Biol.Chem. 2003 278 49183 49190 1UJ5 13679361 Crystal structure of Thermus thermophilus ribose-5-phosphate isomerase complexed with ribose-5-phosphate 2003-07-26 2004-07-13 Hamada, K.,Ago, H.,Sugahara, M.,Nodake, Y.,Kuramitsu, S.,Miyano, M. Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi) J.Biol.Chem. 2003 278 49183 49190 1UJ6 13679361 Crystal structure of Thermus thermophilus ribose-5-phosphate isomerase complexed with arabinose-5-phosphate 2003-07-26 2004-07-13 Hamada, K.,Ago, H.,Sugahara, M.,Nodake, Y.,Kuramitsu, S.,Miyano, M. Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi) J.Biol.Chem. 2003 278 49183 49190 1V3U 15007077 Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form 2003-11-05 2004-07-13 Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M. Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem. 2004 279 22615 22623 1V3V 15007077 Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2 2003-11-06 2004-07-13 Hori, T.,Yokomizo, T.,Ago, H.,Sugahara, M.,Ueno, G.,Yamamoto, M.,Kumasaka, T.,Shimizu, T.,Miyano, M. Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem. 2004 279 22615 22623 1V25 15145952 Crystal structure of tt0168 from Thermus thermophilus HB8 2003-10-07 2004-07-27 Hisanaga, Y.,Ago, H.,Nakagawa, N.,Hamada, K.,Ida, K.,Yamamoto, M.,Hori, T.,Arii, Y.,Sugahara, M.,Kuramitsu, S.,Yokoyama, S.,Miyano, M. Structural Basis of the Substrate-specific Two-step Catalysis of Long Chain Fatty Acyl-CoA Synthetase Dimer J.Biol.Chem. 2004 279 31717 31726 1V26 15145952 Crystal structure of tt0168 from Thermus thermophilus HB8 2003-10-07 2004-07-27 Hisanaga, Y.,Ago, H.,Nakagawa, N.,Hamada, K.,Ida, K.,Yamamoto, M.,Hori, T.,Arii, Y.,Sugahara, M.,Kuramitsu, S.,Yokoyama, S.,Miyano, M. Structural Basis of the Substrate-specific Two-step Catalysis of Long Chain Fatty Acyl-CoA Synthetase Dimer J.Biol.Chem. 2004 279 31717 31726 1VDH 15965735 Structure-based functional identification of a novel heme-binding protein from thermus thermophilus HB8 2004-03-22 2004-09-22 Ebihara, A.,Okamoto, A.,Kousumi, Y.,Yamamoto, H.,Masui, R.,Ueyama, N.,Yokoyama, S.,Kuramitsu, S. Structure-based functional identification of a novel heme-binding protein from Thermus thermophilus HB8. J.STRUCT.FUNCT.GENOM. 2005 6 21 32 1VDH 15965735 Structure-based functional identification of a novel heme-binding protein from thermus thermophilus HB8 2004-03-22 2004-09-22 Ebihara, A.,Okamoto, A.,Kousumi, Y.,Yamamoto, H.,Masui, R.,Ueyama, N.,Yokoyama, S.,Kuramitsu, S. Structure-based functional identification of a novel heme-binding protein from Thermus thermophilus HB8. J.STRUCT.FUNCT.GENOM. 2005 6 21 32 1ULR Crystal structure of tt0497 from Thermus thermophilus HB8 2003-09-16 2004-11-02 Ago, H.,Hamada, K.,Sugahara, M.,Kuroishi, C.,Kuramitsu, S.,Yokoyama, S.,Miyano, M. Crystal structure of tt0497 from Thermus thermophilus HB8 To be Published 0 0 0 0 1ULS Crystal structure of tt0140 from Thermus thermophilus HB8 2003-09-16 2004-11-02 Hisanaga, Y.,Ago, H.,Hamada, K.,Sugahara, M.,Nodake, Y.,Kuramitsu, S.,Yokoyama, S.,Miyano, M. Crystal structure of tt0140 from Thermus thermophilus HB8 To be Published 0 0 0 0 1WVP Structure of chemically modified myoglobin with distal N-tetrazolyl-histidine E7(64) 2004-12-23 2005-01-18 Kamiya, N.,Shiro, Y.,Iwata, T.,Iizuka, T.,Iwasaki, H. Heme environmental structure of a novel artificial myoglobin with a closed heme pocket: site-specific chemical modification producing distal N-tetrazolylhistidine E7 by cyanogen bromide and azide ion J.Am.Chem.Soc. 1991 113 1826 1829 1WN0 15576555 Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize 2004-07-24 2005-01-25 Sugawara, H.,Kawano, Y.,Hatakeyama, T.,Yamaya, T.,Kamiya, N.,Sakakibara, H. Crystal structure of the histidine-containing phosphotransfer protein ZmHP2 from maize Protein Sci. 2005 14 202 208 1WN0 15576555 Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize 2004-07-24 2005-01-25 Sugawara, H.,Kawano, Y.,Hatakeyama, T.,Yamaya, T.,Kamiya, N.,Sakakibara, H. Crystal structure of the histidine-containing phosphotransfer protein ZmHP2 from maize Protein Sci. 2005 14 202 208 1WYT 15791207 Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form 2005-02-17 2005-04-05 Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N. Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia Embo J. 2005 24 1523 1536 1WYU 15791207 Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in holo form 2005-02-17 2005-04-05 Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N. Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia Embo J. 2005 24 1523 1536 1VCD Crystal Structure of a T.thermophilus HB8 Ap6A hydrolase Ndx1 2004-03-05 2005-04-26 Iwai, T.,Nakagawa, N.,Kuramitsu, S.,Masui, R. Crystal Structure of Nudix Protein Ndx1 from Thermus thermophilus HB8 in binary complex with diadenosine hexaphosphate To be Published 0 0 0 0 1WCW Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal) 2004-05-06 2005-05-06 Mizohata, E.,Matsuura, T.,Sakai, H.,Murayama, K.,Terada, T.,Shirouzu, M.,Kuramitsu, S.,Yokoyama, S. Crystal Structure of Uroporphyrinogen III Synthase from Thermus thermophilus HB8 To be Published 0 0 0 0 1WUQ 16169877 Structure of GTP cyclohydrolase I Complexed with 8-oxo-GTP 2004-12-08 2005-07-19 Tanaka, Y.,Nakagawa, N.,Kuramitsu, S.,Yokoyama, S.,Masui, R. Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative J.Biochem.(Tokyo) 2005 138 263 275 1WUR 16169877 Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP 2004-12-08 2005-07-19 Tanaka, Y.,Nakagawa, N.,Kuramitsu, S.,Yokoyama, S.,Masui, R. Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative J.Biochem.(Tokyo) 2005 138 263 275 1WKJ Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8 2004-05-31 2005-08-23 Takeishi, S.,Nakagawa, N.,Masui, R.,Kuramitsu, S. Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8 To be Published 0 0 0 0 1WN5 17959604 Crystal Structure of Blasticidin S Deaminase (BSD) Complexed with Cacodylic Acid 2004-07-27 2005-10-25 Kumasaka, T.,Yamamoto, M.,Furuichi, M.,Nakasako, M.,Teh, A.H.,Kimura, M.,Yamaguchi, I.,Ueki, T. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc J.Biol.Chem. 2007 282 37103 37111 1WN6 17959604 Crystal Structure of Blasticidin S Deaminase (BSD) Complexed with Tetrahedral Intermediate of Blasticidin S 2004-07-27 2005-10-25 Kumasaka, T.,Yamamoto, M.,Furuichi, M.,Nakasako, M.,Teh, A.H.,Kimura, M.,Yamaguchi, I.,Ueki, T. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc J.Biol.Chem. 2007 282 37103 37111 2D0Q Complex of Fe-type NHase with Cyclohexyl isocyanide, photo-activated for 1hr at 277K 2005-08-05 2006-02-05 Nojiri, M.,Kawano, Y.,Hashimoto, K.,Kamiya, N. X-ray snap shots of Inhibitor Binding Process in Photo-reactive Nitrile Hydratase To be Published 0 0 0 0 2D1R 16541080 Crystal structure of the thermostable Japanese firefly Luciferase complexed with OXYLUCIFERIN and AMP 2005-08-31 2006-03-21 Nakatsu, T.,Ichiyama, S.,Hiratake, J.,Saldanha, A.,Kobashi, N.,Sakata, K.,Kato, H. Structural basis for the spectral difference in luciferase bioluminescence. Nature 2006 440 372 376 2D1S 16541080 Crystal structure of the thermostable Japanese Firefly Luciferase complexed with High-energy intermediate analogue 2005-08-31 2006-03-21 Nakatsu, T.,Ichiyama, S.,Hiratake, J.,Saldanha, A.,Kobashi, N.,Sakata, K.,Kato, H. Structural basis for the spectral difference in luciferase bioluminescence. Nature 2006 440 372 376 2DDR 16595670 Crystal structure of sphingomyelinase from Bacillus cereus with calcium ion 2006-02-02 2006-05-02 Ago, H.,Oda, M.,Takahashi, M.,Tsuge, H.,Ochi, S.,Katunuma, N.,Miyano, M.,Sakurai, J. Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus. J.Biol.Chem. 2006 281 16157 16167 2DN1 16765986 1.25A resolution crystal structure of human hemoglobin in the oxy form 2006-04-25 2006-05-09 Park, S.-Y.,Yokoyama, T.,Shibayama, N.,Shiro, Y.,Tame, J.R. 1.25 a resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms. J.Mol.Biol. 2006 360 690 701 2CZT 19546224 lipocalin-type prostaglandin D synthase 2005-07-17 2006-10-03 Kumasaka, T.,Aritake, K.,Ago, H.,Irikura, D.,Tsurumura, T.,Yamamoto, M.,Miyano, M.,Urade, Y.,Hayaishi, O. Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem. 2009 284 22344 22352 2CZU 19546224 lipocalin-type prostaglandin D synthase 2005-07-17 2006-10-03 Kumasaka, T.,Aritake, K.,Ago, H.,Irikura, D.,Tsurumura, T.,Yamamoto, M.,Miyano, M.,Urade, Y.,Hayaishi, O. Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. J.Biol.Chem. 2009 284 22344 22352 2D3Y 17870091 Crystal structure of uracil-DNA glycosylase from Thermus Thermophilus HB8 2005-10-04 2006-10-17 Kosaka, H.,Hoseki, J.,Nakagawa, N.,Kuramitsu, S.,Masui, R. Crystal structure of family 5 uracil-DNA glycosylase bound to DNA. J.Mol.Biol. 2007 373 839 850 2DM6 16916844 Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex 2006-04-20 2006-11-28 Hori, T.,Ishijima, J.,Yokomizo, T.,Ago, H.,Shimizu, T.,Miyano, M. Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy J.Biochem.(Tokyo) 2006 140 457 466 2IPC 17059823 Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer 2006-10-12 2006-11-28 Vassylyev, D.G.,Mori, H.,Vassylyeva, M.N.,Tsukazaki, T.,Kimura, Y.,Tahirov, T.H.,Ito, K. Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer. J.Mol.Biol. 2006 364 248 258 2DQB 17242516 Crystal structure of dNTP triphosphohydrolase from Thermus thermophilus HB8, which is homologous to dGTP triphosphohydrolase 2006-05-25 2007-01-23 Kondo, N.,Nakagawa, N.,Ebihara, A.,Chen, L.,Liu, Z.-J.,Wang, B.-C.,Yokoyama, S.,Kuramitsu, S.,Masui, R. Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis ACTA CRYSTALLOGR.,SECT.D 2007 63 230 239 2YW9 Crystal structure of TT0143 from Thermus thermophilus HB8 2007-04-20 2007-05-15 Ago, H.,Hamada, K.,Ida, K.,Kanda, H.,Sugahara, M.,Yamamoto, M.,Nodake, Y.,Kuramitsu, S.,Yokoyama, S.,Miyano, M. Crystal structure of TT0143 from Thermus thermophilus HB8 To be Published 0 0 0 0 2YQH 17392279 Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the substrate-binding form 2007-03-30 2007-05-22 Maruyama, D.,Nishitani, Y.,Nonaka, T.,Kita, A.,Fukami, T.A.,Mio, T.,Yamada-Okabe, H.,Yamada-Okabe, T.,Miki, K. Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism J.Biol.Chem. 2007 282 17221 17230 2YQJ 17392279 Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the reaction-completed form 2007-03-30 2007-05-22 Maruyama, D.,Nishitani, Y.,Nonaka, T.,Kita, A.,Fukami, T.A.,Mio, T.,Yamada-Okabe, H.,Yamada-Okabe, T.,Miki, K. Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism J.Biol.Chem. 2007 282 17221 17230 2YQS 17392279 Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the product-binding form 2007-03-30 2007-05-22 Maruyama, D.,Nishitani, Y.,Nonaka, T.,Kita, A.,Fukami, T.A.,Mio, T.,Yamada-Okabe, H.,Yamada-Okabe, T.,Miki, K. Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism J.Biol.Chem. 2007 282 17221 17230 2DQ4 Crystal structure of threonine 3-dehydrogenase 2006-05-19 2007-06-12 Omi, R.,Yao, T.,Goto, M.,Miyahara, I.,Hirotsu, K. Crystal structure of threonine 3-dehydrogenase To be Published 0 0 0 0 2EKU 17636874 Crystal structure of myoglobin reconstituted with 7-methyl-7-depropionatehemin 2007-03-25 2007-08-14 Harada, K.,Makino, M.,Sugimoto, H.,Hirota, S.,Matsuo, T.,Shiro, Y.,Hisaeda, Y.,Hayashi, T. Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: functional role of each heme propionate side chain Biochemistry 2007 46 9406 9416 2DXB 19785438 Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers 2006-08-25 2007-08-28 Arakawa, T.,Kawano, Y.,Katayama, Y.,Nakayama, H.,Dohmae, N.,Yohda, M.,Odaka, M. Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification J.Am.Chem.Soc. 2009 131 14838 14843 2E6E 17561111 Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 2006-12-26 2007-08-28 Iwasaki, W.,Miki, K. Crystal Structure of the Stationary Phase Survival Protein SurE with Metal Ion and AMP J.Mol.Biol. 2007 371 123 136 2EGU Crystal structure of O-acetylserine sulfhydrase from Geobacillus kaustophilus HTA426 2007-03-02 2007-09-04 Rehse, P.H.,Yokoyama, S. Crystal structure of O-acetylserine sulfhydrase from Geobacillus kaustophilus HTA426 To be Published 0 0 0 0 2YYK 17804419 Crystal structure of the mutant of HpaB (T198I, A276G, and R466H) 2007-04-30 2007-09-04 Kim, S.-H.,Hisano, T.,Takeda, K.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem. 2007 282 33107 33117 2YYK 17804419 Crystal structure of the mutant of HpaB (T198I, A276G, and R466H) 2007-04-30 2007-09-04 Kim, S.-H.,Hisano, T.,Takeda, K.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem. 2007 282 33107 33117 2YYL 17804419 Crystal structure of the mutant of HpaB (T198I, A276G, and R466H) complexed with FAD 2007-04-30 2007-09-04 Kim, S.-H.,Hisano, T.,Takeda, K.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem. 2007 282 33107 33117 2YYM 17804419 Crystal structure of the mutant of HpaB (T198I, A276G, and R466H) complexed with FAD and 4-hydroxyphenylacetate 2007-04-30 2007-09-04 Kim, S.-H.,Hisano, T.,Takeda, K.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem. 2007 282 33107 33117 2EMQ Hypothetical Conserved Protein (GK1048) from Geobacillus Kaustophilus 2007-03-28 2007-10-02 Rehse, P.H.,Yokoyama, S. Hypothetical Conserved Protein (GK1048) from Geobacillus Kaustophilus To be Published 0 0 0 0 2YV2 Crystal Structure of Succinyl-CoA Synthetase Alpha Chain from Aeropyrum pernix K1 2007-04-06 2007-10-09 Niwa, H.,Kuramitsu, S.,Yokoyama, S. Crystal Structure of Succinyl-CoA Synthetase Alpha Chain from Aeropyrum pernix K1 To be Published 0 0 0 0 2Z3G 17959604 Crystal structure of blasticidin S deaminase (BSD) 2007-06-04 2007-10-23 Kumasaka, T.,Yamamoto, M.,Furuichi, M.,Nakasako, M.,Teh, A.H.,Kimura, M.,Yamaguchi, I.,Ueki, T. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc J.Biol.Chem. 2007 282 37103 37111 2Z3H 17959604 Crystal structure of blasticidin S deaminase (BSD) complexed with deaminohydroxy blasticidin S 2007-06-04 2007-10-23 Kumasaka, T.,Yamamoto, M.,Furuichi, M.,Nakasako, M.,Teh, A.H.,Kimura, M.,Yamaguchi, I.,Ueki, T. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc J.Biol.Chem. 2007 282 37103 37111 2Z3I 17959604 Crystal structure of blasticidin S deaminase (BSD) mutant E56Q complexed with substrate 2007-06-04 2007-10-23 Kumasaka, T.,Yamamoto, M.,Furuichi, M.,Nakasako, M.,Teh, A.H.,Kimura, M.,Yamaguchi, I.,Ueki, T. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc J.Biol.Chem. 2007 282 37103 37111 2Z0J Crystal structure of uncharacterized conserved protein from Thermus thermophilus HB8 2007-05-07 2007-11-13 Nakagawa, N.,Kukimoto-Niino, M.,Yokoyama, S.,Kuramitsu, S. Crystal structure of uncharacterized conserved protein from Thermus thermophilus HB8 To be Published 0 0 0 0 2Z1A Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8 2007-05-08 2007-11-13 Nakakaga, N.,Kishishita, S.,Yokoyama, S.,Kuramitsu, S. Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8 To be Published 0 0 0 0 2ECR 17729270 Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase 2007-02-13 2008-01-15 Kim, S.H.,Hisano, T.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins 2008 70 718 730 2ECU 17729270 Crystal structure of flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase 2007-02-14 2008-01-15 Kim, S.H.,Hisano, T.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins 2008 70 718 730 2ED4 17729270 Crystal structure of flavin reductase HpaC complexed with FAD and NAD 2007-02-14 2008-01-15 Kim, S.H.,Hisano, T.,Iwasaki, W.,Ebihara, A.,Miki, K. Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins 2008 70 718 730 2EFN 18653535 Crystal Structure of Ser 32 to Ala of ST1022 from Sulfolobus tokodaii 7 2007-02-23 2008-02-26 Kumarevel, T.S.,Nakano, N.,Ponnuraj, K.,Gopinath, S.C.,Sakamoto, K.,Shinkai, A.,Kumar, P.K.,Yokoyama, S. Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res. 2008 36 4808 4820 2EFO 18653535 Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7 2007-02-23 2008-02-26 Kumarevel, T.S.,Nakano, N.,Ponnuraj, K.,Gopinath, S.C.,Sakamoto, K.,Shinkai, A.,Kumar, P.K.,Yokoyama, S. Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res. 2008 36 4808 4820 2EFQ 18653535 Crystal Structure of Thr134 to Ala of ST1022-Glutamine Complex from Sulfolobus tokodaii 7 2007-02-23 2008-03-04 Kumarevel, T.S.,Nakano, N.,Ponnuraj, K.,Gopinath, S.C.,Sakamoto, K.,Shinkai, A.,Kumar, P.K.,Yokoyama, S. Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res. 2008 36 4808 4820 2EG2 The crystal structure of PII protein 2007-02-27 2008-03-04 Sakai, H.,Shinkai, A.,Kitamura, Y.,Kuramitsu, S.,Yokoyama, S. The crystal structure of PII protein To be Published 0 0 0 0 2EJV Crystal structure of threonine 3-dehydrogenase complexed with NAD+ 2007-03-20 2008-03-25 Omi, R.,Yao, T.,Goto, M.,Miyahara, I.,Hirotsu, K. Crystal structure of threonine 3-dehydrogenase To be Published 0 0 0 0 2EQ8 Crystal structure of lipoamide dehydrogenase from thermus thermophilus HB8 with psbdp 2007-03-30 2008-04-01 Nakai, T.,Kamiya, N. Crystal structure of lipoamide dehydrogenase from Thermus thermophilus HB8 To be Published 0 0 0 0 2EQ9 Crystal structure of lipoamide dehydrogenase from thermus thermophilus HB8 with psbdb 2007-03-30 2008-04-01 Nakai, T.,Kamiya, N. Crystal structure of lipoamide dehydrogenase from Thermus thermophilus HB8 To be Published 0 0 0 0 2YSK Crystal structure of a hypothetical protein TTHA1432 from Thermus thermophilus 2007-04-03 2008-04-08 Okamoto, A.,Yokoyama, S.,Kuramitsu, S. Crystal structure of a hypothetical protein TTHA1432 from Thermus thermophilus To be Published 0 0 0 0 2YR5 18417467 Crystal structure of L-phenylalanine oxidase from Psuedomonas sp.P501 2007-04-02 2008-04-15 Ida, K.,Kurabayashi, M.,Suguro, M.,Hiruma, Y.,Hikima, T.,Yamomoto, M.,Suzuki, H. Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501. J.Biol.Chem. 2008 283 16584 16590 2ZIY 18463093 Crystal structure of squid rhodopsin 2008-02-27 2008-05-06 Shimamura, T.,Hiraki, K.,Takahashi, N.,Hori, T.,Ago, H.,Masuda, K.,Takio, K.,Ishiguro, M.,Miyano, M. Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region J.Biol.Chem. 2008 283 17753 17756 2ZWH 19158791 Model for the F-actin structure 2008-12-05 2009-01-20 Oda, T.,Iwasa, M.,Aihara, T.,Maeda, Y.,Narita, A. The nature of the globular- to fibrous-actin transition. Nature 2009 457 441 445 3A0U 19836334 Crystal structure of response regulator protein TrrA (TM1360) from Thermotoga maritima in complex with Mg(2+)-BeF (wild type) 2009-03-24 2009-10-20 Yamada, S.,Sugimoto, H.,Kobayashi, M.,Ohno, A.,Nakamura, H.,Shiro, Y. Structure of PAS-linked histidine kinase and the response regulator complex Structure 2009 17 1333 1344 3A0V 19836334 PAS domain of histidine kinase ThkA (TM1359) (SeMet, F486M/F489M) 2009-03-24 2009-10-20 Yamada, S.,Sugimoto, H.,Kobayashi, M.,Ohno, A.,Nakamura, H.,Shiro, Y. Structure of PAS-linked histidine kinase and the response regulator complex Structure 2009 17 1333 1344 3A10 19836334 Crystal structure of response regulator protein TrrA (TM1360) from Thermotoga maritima in complex with Mg(2+)-BeF (SeMet, L89M) 2009-03-25 2009-10-20 Yamada, S.,Sugimoto, H.,Kobayashi, M.,Ohno, A.,Nakamura, H.,Shiro, Y. Structure of PAS-linked histidine kinase and the response regulator complex Structure 2009 17 1333 1344 3AKC Crystal structure of CMP kinase in complex with CDP and ADP from Thermus thermophilus HB8 2010-07-12 2011-07-06 Mega, R.,Nakagawa, N.,Kuramitsu, S.,Masui, R. The crystal structure of the tertiary complex of CMP kinase with a phosphoryl group acceptor and a donor from Thermus thermophilus HB8 To be Published 0 0 0 0 3AKD Crystal structure of CMP kinase in complex with CDP from Thermus thermophilus HB8 2010-07-12 2011-07-06 Mega, R.,Nakagawa, N.,Kuramitsu, S.,Masui, R. The crystal structure of the tertiary complex of CMP kinase with a phosphoryl group acceptor and a donor from Thermus thermophilus HB8 To be Published 0 0 0 0 5B4S 28084023 Crystal Structure of GH80 chitosanase from Mitsuaria chitosanitabida 2016-04-19 2017-02-01 Yorinaga, Y.,Kumasaka, T.,Yamamoto, M.,Hamada, K.,Kawamukai, M. Crystal structure of a family 80 chitosanase from Mitsuaria chitosanitabida FEBS Lett. 2017 591 540 547 6LN2 32152292 Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38) 2019-12-28 2020-03-18 Wu, F.,Yang, L.,Hang, K.,Laursen, M.,Wu, L.,Han, G.W.,Ren, Q.,Roed, N.K.,Lin, G.,Hanson, M.A.,Jiang, H.,Wang, M.W.,Reedtz-Runge, S.,Song, G.,Stevens, R.C. Full-length human GLP-1 receptor structure without orthosteric ligands. Nat Commun 2020 11 1272 1272 6LKP 32170832 Crystal structure of Dps1 from the thermophilic non-heterocystous filamentous cyanobacterium Thermoleptolyngbya sp. 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Determination of the melanocortin-4 receptor structure identifies Ca2+as a cofactor for ligand binding. Science 2020 368 428 433 7BYW 32448506 Crystal structure of Acidovorax avenae L-fucose mutarotase (L-fucose-bound form) 2020-04-24 2020-05-27 Watanabe, Y.,Watanabe, S.,Fukui, Y.,Nishiwaki, H. Functional and structural characterization of a novel L-fucose mutarotase involved in non-phosphorylative pathway of L-fucose metabolism. Biochem.Biophys.Res.Commun. 2020 528 21 27 7CGR Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase E147A mutant (NADP and glycerol bound form) 2020-07-02 2020-07-29 Yoshiwara, K.,Watanabe, S.,Watanabe, Y. Crystal structure of bacterial L-arabinose 1-dehydrogenase in complex with L-arabinose and NADP+ Biochem.Biophys.Res.Commun. 2020 530 203 208 7CKJ 32469932 Crystal structure of CMP kinase in complex with CMP from Thermus thermophilus HB8 2020-07-17 2020-07-29 Mega, R.,Nakagawa, N.,Kuramitsu, S.,Masui, R. The crystal structures of Thermus thermophilus CMP kinase complexed with a phosphoryl group acceptor and donor. PLoS ONE 2020 15 0 0 7C0D 32697085 Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (Hydroxypyruvate-bound form) 2020-05-01 2020-08-05 Watanabe, S.,Watanabe, Y.,Nobuchi, R.,Ono, A. Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry 2020 59 2962 2973 7C0E 32697085 Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (2-oxobutyrate-bound form) 2020-05-01 2020-08-05 Watanabe, S.,Watanabe, Y.,Nobuchi, R.,Ono, A. Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. 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Rsc Adv 2021 11 37604 37611 7W2I 35158209 Crystal structure of LOG (Rv1205) from Mycobacterium tuberculosis 2021-11-23 2022-07-06 Shang, L.,Li, G.,Lin, Q.,Ou, M.,Liang, J.,Xiao, G.,Wang, Z.,Cui, S.,Zhang, T.,Liu, L.,Zhang, G. Crystal structure of the cytokinin-producing enzyme ""lonely guy"" (LOG) from Mycobacterium tuberculosis. Biochem.Biophys.Res.Commun. 2022 598 113 118 7TY3 35859865 Crystal Structure of SETD2 Bound to an Indole-based Inhibitor 2022-02-11 2022-08-31 Alford, J.S.,Lampe, J.W.,Brach, D.,Chesworth, R.,Cosmopoulos, K.,Duncan, K.W.,Eckley, S.T.,Kutok, J.L.,Raimondi, A.,Riera, T.V.,Shook, B.,Tang, C.,Totman, J.,Farrow, N.A. Conformational-Design-Driven Discovery of EZM0414: A Selective, Potent SETD2 Inhibitor for Clinical Studies. 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Nat Commun 2022 13 5270 5270 7W9D Crystal Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 (P450BM3) Heme Domain with N-Hexadecanoyl-L-Homoserine 2021-12-09 2022-12-14 Karasawa, M.,Stanfield, J.K.,Kasai, C.,Sugimoto, H.,Shoji, O. Crystal Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 (P450BM3) Heme Domain with N-Hexadecanoyl-L-Homoserine To Be Published 0 0 0 0 7W9J Crystal Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 (P450BM3) Heme Domain with N-Dodecanoyl-L-Homoserine Lactone 2021-12-09 2022-12-14 Karasawa, M.,Stanfield, J.K.,Kasai, C.,Sugimoto, H.,Shoji, O. 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Proc.Natl.Acad.Sci.USA 2022 119 0 0 7WY1 36519803 Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styerene 2022-02-15 2023-01-04 Suzuki, K.,Stanfield, J.K.,Omura, K.,Shisaka, Y.,Ariyasu, S.,Kasai, C.,Aiba, Y.,Sugimoto, H.,Shoji, O. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl. 2023 62 0 0 7WY3 36519803 Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87V Mutant Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with Styrene 2022-02-15 2023-01-04 Suzuki, K.,Stanfield, J.K.,Omura, K.,Shisaka, Y.,Ariyasu, S.,Kasai, C.,Aiba, Y.,Sugimoto, H.,Shoji, O. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl. 2023 62 0 0 7WY4 36519803 Structure of the CYP102A1 F87A Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene 2022-02-15 2023-01-04 Suzuki, K.,Stanfield, J.K.,Omura, K.,Shisaka, Y.,Ariyasu, S.,Kasai, C.,Aiba, Y.,Sugimoto, H.,Shoji, O. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl. 2023 62 0 0 7WG0 Structure of the Manganese Protoporphyrin IX-Reconstituted CYP102A1 Heme Domain with N-palmitoyl-L-phenylalanine 2021-12-27 2023-01-11 Keita, O.,Osami, S.,Yuichiro, A.,Hiroshi, S. Structure of the Manganese Protoporphyrin IX-Reconstituted CYP102A1 Heme Domain with N-palmitoyl-L-phenylalanine To Be Published 0 0 0 0 7YQ0 36592583 Crystal structure of adenosine 5'-phosphosulfate kinase from Archaeoglobus fulgidus in complex with ADP 2022-08-05 2023-01-18 Kawakami, T.,Teramoto, T.,Kakuta, Y. Crystal structure of adenosine 5'-phosphosulfate kinase isolated from Archaeoglobus fulgidus. Biochem.Biophys.Res.Commun. 2022 643 105 110 7YQ1 36592583 Crystal structure of adenosine 5'-phosphosulfate kinase from Archaeoglobus fulgidus in complex with AMP-PNP and APS 2022-08-05 2023-01-18 Kawakami, T.,Teramoto, T.,Kakuta, Y. Crystal structure of adenosine 5'-phosphosulfate kinase isolated from Archaeoglobus fulgidus. Biochem.Biophys.Res.Commun. 2022 643 105 110 7WOL Crystal structure of lipase TrLipB from Thermomocrobium roseum 2022-01-21 2023-01-25 Fang, Y.,Xin, Y.,Shi, Y.,Gu, Z.,Zhang, L. Crystal structure of lipase TrLipB from Thermomocrobium roseum To Be Published 0 0 0 0 8GSR 36563174 Crystal structure of L-2,4-diketo-3-deoxyrhamnonate hydrolase from Sphingomonas sp. (apo-form) 2022-09-07 2023-02-08 Fukuhara, S.,Watanabe, S.,Watanabe, Y.,Nishiwaki, H. Crystal Structure of l-2,4-Diketo-3-deoxyrhamnonate Hydrolase Involved in the Nonphosphorylated l-Rhamnose Pathway from Bacteria. Biochemistry 2023 62 524 534 8GST 36563174 Crystal structure of L-2,4-diketo-3-deoxyrhamnonate hydrolase from Sphingomonas sp. (pyruvate bound-form) 2022-09-07 2023-02-08 Fukuhara, S.,Watanabe, S.,Watanabe, Y.,Nishiwaki, H. Crystal Structure of l-2,4-Diketo-3-deoxyrhamnonate Hydrolase Involved in the Nonphosphorylated l-Rhamnose Pathway from Bacteria. Biochemistry 2023 62 524 534 7Y9P 36732376 Xylitol dehydrogenase S96C/S99C/Y102C mutant(thermostabilized form) from Pichia stipitis 2022-06-25 2023-02-15 Yoshiwara, K.,Watanabe, S.,Watanabe, Y. Molecular evolutionary insight of structural zinc atom in yeast xylitol dehydrogenases and its application in bioethanol production by lignocellulosic biomass. Sci Rep 2023 13 1920 1920 8F15 Structure of the STUB1 TPR domain in complex with H202, an all-D Helicon Polypeptide 2022-11-04 2023-02-15 Callahan, A.J.,Gandhesiri, S.,Travaline, T.L.,Lozano Salazar, L,Hanna, S.,Lee, Y.-C.,Li, K.,Tokareva, O.S.,Swiecicki, J.-M.,Loas, A.,Verdine, G.L.,McGee, J.H.,Pentelute, B.L. Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display Chemrxiv 2023 0 0 0 7XLP 36622773 MEK1 bound to DS03090629 2022-04-22 2023-03-01 Takano, K.,Munehira, Y.,Hatanaka, M.,Murakami, R.,Shibata, Y.,Shida, T.,Takeuchi, K.,Takechi, S.,Tabata, T.,Shimada, T.,Kishikawa, S.,Matsui, Y.,Ubukata, O.,Seki, T.,Kaneta, Y. Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther. 2023 22 317 332 8HH0 36888722 Peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) 2022-11-16 2023-03-22 Himiyama, T.,Hamaguchi, T.,Yonekura, K.,Nakamura, T. Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins. Bioconjug.Chem. 2023 0 0 0 8GTK 36991125 Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex 2022-09-08 2023-04-12 Zhong, X.,Zeng, H.,Zhou, Z.,Su, Y.,Cheng, H.,Hou, Y.,She, Y.,Feng, N.,Wang, J.,Shao, F.,Ding, J. Structural mechanisms for regulation of GSDMB pore-forming activity. Nature 2023 616 598 605 8EG5 37104712 huCaspase-6 in complex with inhibitor 3a 2022-09-11 2023-05-10 Van Horn, K.S.,Wang, D.,Medina-Cleghorn, D.,Lee, P.S.,Bryant, C.,Altobelli, C.,Jaishankar, P.,Leung, K.K.,Ng, R.A.,Ambrose, A.J.,Tang, Y.,Arkin, M.R.,Renslo, A.R. Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. J.Am.Chem.Soc. 2023 145 10015 10021 8EG6 37104712 huCaspase-6 in complex with inhibitor 2a 2022-09-11 2023-05-10 Van Horn, K.S.,Wang, D.,Medina-Cleghorn, D.,Lee, P.S.,Bryant, C.,Altobelli, C.,Jaishankar, P.,Leung, K.K.,Ng, R.A.,Ambrose, A.J.,Tang, Y.,Arkin, M.R.,Renslo, A.R. Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. J.Am.Chem.Soc. 2023 145 10015 10021 7YC9 36912866 Co-crystal structure of BTK kinase domain with inhibitor 2022-07-01 2023-05-17 Guo, Y.,Hu, N.,Liu, Y.,Zhang, W.,Yu, D.,Shi, G.,Zhang, B.,Yin, L.,Wei, M.,Yuan, X.,Luo, L.,Wang, F.,Song, X.,Xin, L.,Wei, Q.,Li, Y.,Guo, Y.,Chen, S.,Zhang, T.,Zhang, S.,Zhou, X.,Zhang, C.,Su, D.,Liu, J.,Cheng, Z.,Zhang, J.,Xing, H.,Sun, H.,Li, X.,Zhao, Y.,He, M.,Wu, Y.,Guo, Y.,Sun, X.,Tian, A.,Zhou, C.,Young, S.,Liu, X.,Wang, L.,Wang, Z. Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases. J.Med.Chem. 2023 66 4025 4044 7XOF Crystal structure of Oryza sativa plastid glycyl-tRNA synthetase 2022-05-01 2023-05-24 Hao, Q.,Yu, Z.,Lu, G.,Lin, J. Crystal structure of Oryza sativa plastid glycyl-tRNA synthetase To be published 0 0 0 0 7XZK Crystal Structure of P450BM3 with N-(3-cyclohexylpropanoyl)-L-pipecolyl-L-phenylalanine 2022-06-02 2023-06-07 Ariyasu, S.,Yonemura, K.,Kasai, C.,Aiba, Y.,Onoda, H.,Shisaka, Y.,Sugimoto, H.,Tosha, T.,Kubo, M.,Kamachi, T.,Yoshizawa, K.,Shoji, O. Crystal Structure of P450BM3 with N-(3-cyclohexylpropanoyl)-L-pipecolyl-L-phenylalanine To Be Published 0 0 0 0 8GSX 37071018 X-ray structure of Clostridium perfringens pili protein B collagen-binding domains 2022-09-07 2023-06-07 Tamai, E.,Yamada, M.,Ishida, T.,Arimura, N.,Matsunami, R.,Sekiya, H.,Kamitori, S. Structural and biochemical characterization of Clostridium perfringens pili protein B collagen-binding domains. Febs Lett. 2023 597 1345 1354 8JBJ 37229604 Crystal structure of anti-PVRIG Fab 2023-05-09 2023-06-21 Yi, M.,Sun, J.,Sun, H.,Wang, Y.,Hou, S.,Jiang, B.,Xie, Y.,Ji, R.,Xue, L.,Ding, X.,Song, X.,Xu, A.,Huang, C.,Quan, Q.,Song, J. Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity. Mabs 2023 15 2215364 2215364 8GV1 37339067 Crystal structure of anti-FX IgG fab with FAST-Ig mutations 2022-09-14 2023-06-28 Koga, H.,Yamano, T.,Betancur, J.,Nagatomo, S.,Ikeda, Y.,Yamaguchi, K.,Nabuchi, Y.,Sato, K.,Teranishi-Ikawa, Y.,Sato, M.,Hirayama, H.,Hayasaka, A.,Torizawa, T.,Haraya, K.,Sampei, Z.,Shiraiwa, H.,Kitazawa, T.,Igawa, T.,Kuramochi, T. Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs 2023 15 2222441 2222441 8GV2 37339067 Crystal structure of anti-FX IgG fab without FAST-Ig mutations 2022-09-14 2023-06-28 Koga, H.,Yamano, T.,Betancur, J.,Nagatomo, S.,Ikeda, Y.,Yamaguchi, K.,Nabuchi, Y.,Sato, K.,Teranishi-Ikawa, Y.,Sato, M.,Hirayama, H.,Hayasaka, A.,Torizawa, T.,Haraya, K.,Sampei, Z.,Shiraiwa, H.,Kitazawa, T.,Igawa, T.,Kuramochi, T. Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs 2023 15 2222441 2222441 7Y40 Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus 2022-06-13 2023-07-05 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8H1K 37314406 Crystal structure of glucose-2-epimerase from Runella slithyformis Runsl_4512 2022-10-03 2023-07-12 Wang, H.,Sun, X.,Saburi, W.,Hashiguchi, S.,Yu, J.,Ose, T.,Mori, H.,Yao, M. Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis. Acta Crystallogr D Struct Biol 2023 79 585 595 8H1M 37314406 Crystal structure of glucose-2-epimerase mutant_D254A from Runella slithyformis Runsl_4512 2022-10-03 2023-07-12 Wang, H.,Sun, X.,Saburi, W.,Hashiguchi, S.,Yu, J.,Ose, T.,Mori, H.,Yao, M. Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis. Acta Crystallogr D Struct Biol 2023 79 585 595 8H1N 37314406 Crystal structure of glucose-2-epimerase mutant_D254A in complex with D-Glucitol from Runella slithyformis Runsl_4512 2022-10-03 2023-07-12 Wang, H.,Sun, X.,Saburi, W.,Hashiguchi, S.,Yu, J.,Ose, T.,Mori, H.,Yao, M. Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis. Acta Crystallogr D Struct Biol 2023 79 585 595 7YV1 37874670 Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab 2022-08-18 2023-07-26 Ohta, A.,Tanada, M.,Shinohara, S.,Morita, Y.,Nakano, K.,Yamagishi, Y.,Takano, R.,Kariyuki, S.,Iida, T.,Matsuo, A.,Ozeki, K.,Emura, T.,Sakurai, Y.,Takano, K.,Higashida, A.,Kojima, M.,Muraoka, T.,Takeyama, R.,Kato, T.,Kimura, K.,Ogawa, K.,Ohara, K.,Tanaka, S.,Kikuchi, Y.,Hisada, N.,Hayashi, R.,Nishimura, Y.,Nomura, K.,Tachibana, T.,Irie, M.,Kawada, H.,Torizawa, T.,Murao, N.,Kotake, T.,Tanaka, M.,Ishikawa, S.,Miyake, T.,Tamiya, M.,Arai, M.,Chiyoda, A.,Akai, S.,Sase, H.,Kuramoto, S.,Ito, T.,Shiraishi, T.,Kojima, T.,Iikura, H. Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc. 2023 145 24035 24051 8K4W Structure of a triple-helix region of human collagen type I from Trautec 2023-07-20 2023-08-02 Chu, Y.,Zhai, Y.,Fan, X.,Li, J.,Wang, L.,Fu, S.,Feng, P.,Qian, S. Structure of a triple-helix region of human collagen type I from Trautec. To Be Published 0 0 0 0 8K4X Structure of a triple-helix region of human Collagen type XVII from Trautec 2023-07-20 2023-08-02 Chu, Y.,Zhai, Y.,Fan, X.,Li, J.,Wang, L.,Fu, S.,Feng, P.,Qian, S. Structure of a triple-helix region of human Collagen type XVII from Trautec. To Be Published 0 0 0 0 7YRO Crystal structure of mango fucosyltransferase 13 2022-08-10 2023-08-16 Okada, T.,Teramoto, T.,Ihara, H.,Ikeda, Y.,Kakuta, Y. Crystal structure of mango alpha1,3/alpha1,4-fucosyltransferase elucidates unique elements strictly regulating its type I-dominant acceptor preference To Be Published 0 0 0 0 7YRS 38239764 Crystal structure of Lactobacillus rhamnosus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI complexed with MOPS 2022-08-10 2023-08-16 Iwase, H.,Yamamoto, Y.,Yamada, A.,Kawai, K.,Oiki, S.,Watanabe, D.,Mikami, B.,Takase, R.,Hashimoto, W. Crystal Structures of Lacticaseibacillus 4-Deoxy-L- threo- 5-hexosulose-uronate Ketol-isomerase KduI in Complex with Substrate Analogs. J Appl Glycosci (1999) 2023 70 99 107 8JWY 38319473 Crystal structure of A2AR-T4L in complex with 2-118 2023-06-29 2023-08-16 Weng, Y.,Yang, X.,Zhang, Q.,Chen, Y.,Xu, Y.,Zhu, C.,Xie, Q.,Wang, Y.,Yang, H.,Liu, M.,Lu, W.,Song, G. Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors. Sci China Life Sci 2024 0 0 0 8JWZ 38319473 Crystal structure of A2AR-T4L in complex with AB928 2023-06-29 2023-08-16 Weng, Y.,Yang, X.,Zhang, Q.,Chen, Y.,Xu, Y.,Zhu, C.,Xie, Q.,Wang, Y.,Yang, H.,Liu, M.,Lu, W.,Song, G. Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors. Sci China Life Sci 2024 0 0 0 8GOH Homotetramic Antiparallel Coiled-Coil of 23-residues LacI C-terminal tetramerization helix 2022-08-25 2023-08-30 Otsuka, Y.,Osaki, A.,Nakamura, Y.,Mizuno, N.,Kawamura, T.,Hasegawa, K.,Yamaguchi, H.,Kumasaka, T. Design of interchain Glu-Arg salt-bridges stabilizing heterotetrameric coiled-coil derived from Lac repressor. To Be Published 0 0 0 0 8GOI 23-residues Heterotetramic Antiparallel Coiled-Coil Derived From LacI 2022-08-25 2023-08-30 Otsuka, Y.,Osaki, A.,Nakamura, Y.,Mizuno, N.,Kawamura, T.,Hasegawa, K.,Yamaguchi, H.,Kumasaka, T. Design of interchain Glu-Arg salt-bridges stabilizing heterotetrameric coiled-coil derived from Lac repressor. To Be Published 0 0 0 0 8GOJ 23-residues Heterotetramic Antiparallel Coiled-Coil Derived From LacI 2022-08-25 2023-08-30 Otsuka, Y.,Kumasaka, T. Design of interchain Glu-Arg salt-bridges stabilizing heterotetrameric coiled-coil derived from Lac repressor. To Be Published 0 0 0 0 8SZS 37625785 Cat DHX9 bound to GDP 2023-05-30 2023-09-06 Gotur, D.,Case, A.,Liu, J.,Sickmier, E.A.,Holt, N.,Knockenhauer, K.E.,Yao, S.,Lee, Y.T.,Copeland, R.A.,Buker, S.M.,Boriack-Sjodin, P.A. Development of assays to support identification and characterization of modulators of DExH-box helicase DHX9. Slas Discov 2023 28 376 384 8TDU 37623743 STX-478, a Mutant-Selective, Allosteric Inhibitor bound to PI3Kalpha 2023-07-05 2023-09-06 Buckbinder, L.,St Jean Jr., D.J.,Tieu, T.,Ladd, B.,Hilbert, B.,Wang, W.,Alltucker, J.T.,Manimala, S.,Kryukov, G.V.,Brooijmans, N.,Dowdell, G.,Jonsson, P.,Huff, M.,Guzman-Perez, A.,Jackson, E.L.,Goncalves, M.D.,Stuart, D.D. STX-478, a Mutant-Selective, Allosteric PI3K alpha Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3K alpha-Mutant Xenografts. Cancer Discov 2023 13 2432 2447 8ISN 37661929 HLA-A24 in complex with modified 9mer WT1 peptide 2023-03-21 2023-09-13 Bekker, G.J.,Numoto, N.,Kawasaki, M.,Hayashi, T.,Yabuno, S.,Kozono, Y.,Shimizu, T.,Kozono, H.,Ito, N.,Oda, M.,Kamiya, N. Elucidation of binding mechanism, affinity, and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Sci. 2023 32 0 0 8K9Y 37586213 Crystal structure of Arabidopsis thaliana sulfotransferase SOT16 involved in glucosinolate biosynthesis 2023-08-02 2023-09-13 Iwamoto, Y.,Saito, S.,Teramoto, T.,Maruyama-Nakashita, A.,Kakuta, Y. Crystal structure of Arabidopsis thaliana sulfotransferase SOT16 involved in glucosinolate biosynthesis. Biochem.Biophys.Res.Commun. 2023 677 149 154 8WD2 The Crystal Structure of p53 from Biortus. 2023-09-14 2023-10-04 Wang, F.,Cheng, W.,Yuan, Z.,Sun, N.,Qi, J.,Lu, Y. The Crystal Structure of p53 from Biortus. To Be Published 0 0 0 0 8EI2 37914719 Crystal structure of the N-terminal domain of CUL5 in complex with H314, a Helicon Polypeptide 2022-09-14 2023-10-25 Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun 2023 14 6992 6992 8EI3 37914719 Crystal structure of VHL in complex with H313, a Helicon Polypeptide 2022-09-14 2023-10-25 Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun 2023 14 6992 6992 8EI6 37914719 Crystal structure of the WWP2 HECT domain in complex with H305, a Helicon Polypeptide 2022-09-14 2023-10-25 Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun 2023 14 6992 6992 8EI8 37914719 Crystal structure of the WWP2 HECT domain in complex with H308, a Helicon Polypeptide 2022-09-14 2023-10-25 Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun 2023 14 6992 6992 8H8Q Fab-amyloid beta fragment complex at neutral pH 2022-10-24 2023-10-25 Irie, K.,Irie, Y.,Matsushima, Y.,Kita, A.,Miki, K. Fab-amyloid beta fragment complex at neutral pH To Be Published 0 0 0 0 8JI8 Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti 2023-05-26 2023-11-01 Zhu, X.,Zhang, L.,Chen, H.,Tang, Y.,Jiang, L.,Ding, H.,Yang, X.,Bao, P.,Liao, C.,Li, J.,Ren, D.,Vavricka, C.J.,Strand, M.R.,Han, Q. Mosquitoes have evolved two types of prophenoloxidases To Be Published 0 0 0 0 8W84 HLA-DQ2.5-alpha2 gliadin peptide in complex with DQN0344AE02 2023-08-31 2023-11-08 Okura, Y.,Ikawa-Teranishi, Y.,Mizoroki, A.,Takahashi, N.,Tsushima, T.,Irie, M.,Harfuddin, Z.,Miura-Okuda, M.,Ito, S.,Nakamura, G.,Takesue, H.,Ozono, Y.,Nishihara, M.,Yamada, K.,Gan, S.W.,Hayasaka, A.,Ishii, S.,Wakabayashi, T.,Muraoka, M.,Nagaya, N.,Hino, H.,Nemoto, T.,Kuramochi, T.,Torizawa, T.,Shimada, H.,Kitazawa, T.,Okazaki, M.,Nezu, J.,Sollid, L.M.,Igawa, T. Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease Nat Commun 2023 14 8502 0 8W86 HLA-DQ2.5-B/C hordein peptide in complex with DQN0385AE02 2023-08-31 2023-11-08 Okura, Y.,Ikawa-Teranishi, Y.,Mizoroki, A.,Takahashi, N.,Tsushima, T.,Irie, M.,Harfuddin, Z.,Miura-Okuda, M.,Ito, S.,Nakamura, G.,Takesue, H.,Ozono, Y.,Nishihara, M.,Yamada, K.,Gan, S.W.,Hayasaka, A.,Ishii, S.,Wakabayashi, T.,Muraoka, M.,Nagaya, N.,Hino, H.,Nemoto, T.,Kuramochi, T.,Torizawa, T.,Shimada, H.,Kitazawa, T.,Okazaki, M.,Nezu, J.,Sollid, L.M.,Igawa, T. Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease Nat Commun 2023 14 8502 0 8WR8 The Crystal Structure of cGAS from Biortus 2023-10-13 2023-11-15 Wang, F.,Cheng, W.,Yuan, Z.,Lin, D.,Guo, S. The Crystal Structure of cGAS from Biortus To Be Published 0 0 0 0 8WRA The Crystal Structure of CASP1 from Biortus 2023-10-13 2023-11-15 Wang, F.,Cheng, W.,Yuan, Z.,Lin, D.,Guo, S. The Crystal Structure of CASP1 from Biortus. To Be Published 0 0 0 0 8WSW The Crystal Structure of LIMK2a from Biortus 2023-10-17 2023-11-15 Wang, F.,Cheng, W.,Yuan, Z.,Lin, D.,Pan, W. The Crystal Structure of LIMK2a from Biortus. To Be Published 0 0 0 0 8WTF The Crystal Structure of IRAK4 from Biortus 2023-10-18 2023-11-15 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Xu, Y. The Crystal Structure of IRAK4 from Biortus To Be Published 0 0 0 0 8WFR The Crystal Structure of PCSK9 from Biortus. 2023-09-20 2023-11-22 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Lu, Y. The Crystal Structure of PCSK9 from Biortus. To Be Published 0 0 0 0 8WFY The Crystal Structure of SHP2 from Biortus. 2023-09-20 2023-11-22 Wang, F.,Cheng, W.,Yuan, Z.,Qi, J.,Li, J. The Crystal Structure of SHP2 from Biortus. To Be Published 0 0 0 0 8X2P The Crystal Structure of LCK from Biortus. 2023-11-10 2023-11-22 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Lu, Y. The Crystal Structure of LCK from Biortus. To Be Published 0 0 0 0 8X2Q The Crystal Structure of APC from Biortus. 2023-11-10 2023-11-22 Wang, F.,Cheng, W.,Lv, Z.,Ju, C.,Bao, C. The Crystal Structure of APC from Biortus. To Be Published 0 0 0 0 8JQO 38029967 Protocatecuate hydroxylase from Xylophilus ampelinus complexed with imidazole 2023-06-14 2023-12-06 Katsuki, N.,Fukushima, R.,Doi, Y.,Masuo, S.,Arakawa, T.,Yamada, C.,Fushinobu, S.,Takaya, N. Protocatechuate hydroxylase is a novel group A flavoprotein monooxygenase with a unique substrate recognition mechanism. J.Biol.Chem. 2023 300 105508 105508 8F96 Compound 3 bound to procaspase-6 2022-11-23 2023-12-13 Fan, P.,Zhao, Y.,Renslo, A.R.,Arkin, M.R. A Comprehensive Empirical-Computational Study of Diverse Heteroarene Stacking Interactions Under Physiological Conditions To Be Published 0 0 0 0 8HNE Crystal structure of the ancestral GH19 chitinase Anc4 2022-12-07 2023-12-13 Kozome, D.,Laurino, P. Emergence of antifungal activity in GH19 chitinases through gain-of-function in a remote loop. To Be Published 0 0 0 0 8J2H Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (N137A) in jellyfish Cytaeis uchidae from Biortus 2023-04-14 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8J2I Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (Q140S) in jellyfish Cytaeis uchidae from Biortus 2023-04-14 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8J2J Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (Y187F) in jellyfish Cytaeis uchidae from Biortus 2023-04-14 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8J2K Crystal structure of a bright green fluorescent protein (StayGold) with double mutation (N137A, Q140S) in jellyfish Cytaeis uchidae from Biortus 2023-04-14 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8J2L Crystal structure of a bright green fluorescent protein (StayGold) with double mutations (N137A, Y187F) in jellyfish Cytaeis uchidae from Biortus 2023-04-14 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8J3J Crystal structure of a bright green fluorescent protein (StayGold) with double mutations (Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus 2023-04-17 2023-12-13 Wu, J.,Wang, F.,Gui, W.,Cheng, W.,Yang, Y. Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published 0 0 0 0 8KAD 38065949 Crystal structure of an antibody light chain tetramer with 3D domain swapping 2023-08-02 2023-12-27 Sakai, T.,Mashima, T.,Kobayashi, N.,Ogata, H.,Duan, L.,Fujiki, R.,Hengphasatporn, K.,Uda, T.,Shigeta, Y.,Hifumi, E.,Hirota, S. Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nat Commun 2023 14 7807 7807 8XB9 The Crystal Structure of polo-box domain of PLK1 from Biortus. 2023-12-06 2023-12-27 Wang, F.,Cheng, W.,Yuan, Z.,Meng, Q.,Zhang, B. The Crystal Structure of polo-box domain of PLK1 from Biortus To Be Published 0 0 0 0 8XFL The Crystal Structure of MARK4 from Biortus. 2023-12-14 2023-12-27 Wang, F.,Cheng, W.,Yuan, Z.,Qi, J.,Li, J. The Crystal Structure of MARK4 from Biortus. To Be Published 0 0 0 0 8XFM The Crystal Structure of MNK2 from Biortus. 2023-12-14 2023-12-27 Wang, F.,Cheng, W.,Yuan, Z.,Qi, J.,Li, J. The Crystal Structure of MNK2 from Biortus. To Be Published 0 0 0 0 8XOY The Crystal Structure of PTP1B from Biortus. 2024-01-02 2024-01-24 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Li, J. The Crystal Structure of PTP1B from Biortus. To Be Published 0 0 0 0 8XPV The Crystal Structure of EphA2 from Biortus. 2024-01-04 2024-01-24 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Xu, Y. The Crystal Structure of EphA2 from Biortus. To Be Published 0 0 0 0 8XU5 The Crystal Structure of RORgT from Biortus. 2024-01-12 2024-01-24 Wang, F.,Cheng, W.,Yuan, Z.,Qi, J.,Wu, B. The Crystal Structure of RORgT from Biortus. To Be Published 0 0 0 0 8JEL 38460520 Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I 2023-05-16 2024-02-28 Sun, J.,Zhang, X.,Xue, L.,Cheng, L.,Zhang, J.,Chen, X.,Shen, Z.,Li, K.,Wang, L.,Huang, C.,Song, J. Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure 2024 0 0 0 8JEN 38460520 Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II 2023-05-16 2024-02-28 Sun, J.,Zhang, X.,Xue, L.,Cheng, L.,Zhang, J.,Chen, X.,Shen, Z.,Li, K.,Wang, L.,Huang, C.,Song, J. Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure 2024 0 0 0 8JEO 38460520 Crystal structure of TIGIT in complexed with Tiragolumab 2023-05-16 2024-02-28 Sun, J.,Zhang, X.,Xue, L.,Cheng, L.,Zhang, J.,Chen, X.,Shen, Z.,Li, K.,Wang, L.,Huang, C.,Song, J. Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure 2024 0 0 0 8JT8 Crystal structure of 5-HT2AR in complex with (R)-IHCH-7179 2023-06-21 2024-02-28 Chen, Z.,Yu, J.,Wang, H.,Xu, P.,Fan, L.,Zhang, P.,Huang, H.,Gu, S.,Zhang, B.,Zhou, Y.,Wan, X.,Pei, G.,Xu, H.,Cheng, J.,Wang, S. Flexible Scaffold-based Cheminformatics Approach for Polypharmacological Drug Design To Be Published 0 0 0 0 8JUC 38358126 Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening 2023-06-26 2024-02-28 Loh, Y.Y.,Anantharajan, J.,Huang, Q.,Xu, W.,Fulwood, J.,Ng, H.Q.,Ng, E.Y.,Gea, C.Y.,Choong, M.L.,Tan, Q.W.,Koh, X.,Lim, W.H.,Nacro, K.,Cherian, J.,Baburajendran, N.,Ke, Z.,Kang, C. Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening. Protein Sci. 2024 33 0 0 8XEY The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus 2023-12-13 2024-03-06 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Zhang, B. The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus To Be Published 0 0 0 0 8XI8 The Crystal Structure of TAB1 from Biortus. 2023-12-19 2024-03-06 Wang, F.,Cheng, W.,Lv, Z.,Ju, C.,Bao, C. The Crystal Structure of TAB1 from Biortus. To Be Published 0 0 0 0 8XOV The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. 2024-01-02 2024-03-06 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Zhang, B. The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. To Be Published 0 0 0 0 8XPG The Crystal Structure of polo box domain of Plk4 from Biortus. 2024-01-03 2024-03-06 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Zhang, B. The Crystal Structure of polo box domain of Plk4 from Biortus. To Be Published 0 0 0 0 8XPX The Crystal Structure of PARP12 from Biortus. 2024-01-04 2024-03-06 Wang, F.,Cheng, W.,Lv, Z.,Qi, J.,Shen, Z. The Crystal Structure of PARP12 from Biortus. To Be Published 0 0 0 0 8YGX Structure of the PYK2 from Biortus. 2024-02-27 2024-03-13 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Zhang, B. Structure of the PYK2 from Biortus. To Be Published 0 0 0 0 8YHF The Crystal Structure of the Type I TGF beta receptor from Biortus. 2024-02-28 2024-03-13 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Xu, Y. The Crystal Structure of the Type I TGF beta receptor from Biortus. To Be Published 0 0 0 0 8YHS The Crystal Structure of BRDT from Biortus. 2024-02-28 2024-03-13 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Lu, Y. The Crystal Structure of BRDT from Biortus. To Be Published 0 0 0 0 8YHV Structure of the VP40 from Biortus. 2024-02-28 2024-03-13 Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Zhang, B. Structure of the VP40 from Biortus. To Be Published 0 0 0 0 8IQP Crystal structure of Anti-PEG antibody M9 Fv-clasp fragment with PEG (co-crystallization with PEG3350) 2023-03-17 2024-03-20 Liu, Y.,Mori, T.,Teramoto, T.,Kakuta, Y.,Mori, T. Comparation of structures and binding properties between two anti-polyethylene glycol antibodies induced via T cell-independent and T cell-dependent pathway To Be Published 0 0 0 0 8IQQ Crystal structure of Anti-PEG antibody M9 Fv-clasp fragment with PEG (co-crystallization with PEG2000MME) 2023-03-17 2024-03-20 Liu, Y.,Mori, T.,Teramoto, T.,Kakuta, Y.,Mori, T. Comparation of structures and binding properties between two anti-polyethylene glycol antibodies induced via T cell-independent and T cell-dependent pathway To Be Published 0 0 0 0 8IQR Crystal structure of Anti-PEG antibody M9 Fv-clasp fragment with PEG (co-crystallization with PEG550DME) 2023-03-17 2024-03-20 Liu, Y.,Mori, T.,Teramoto, T.,Kakuta, Y.,Mori, T. Comparation of structures and binding properties between two anti-polyethylene glycol antibodies induced via T cell-independent and T cell-dependent pathway To Be Published 0 0 0 0 8IQS Crystal structure of Anti-PEG antibody M11 Fv-clasp fragment with PEG (co-crystallization with PEG3350) 2023-03-17 2024-03-20 Liu, Y.,Mori, T.,Teramoto, T.,Kakuta, Y.,Mori, T. Comparation of structures and binding properties between two anti-polyethylene glycol antibodies induced via T cell-independent and T cell-dependent pathway To Be Published 0 0 0 0 8TH5 37425880 Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant 2023-07-13 2024-03-20 Yang, Z.,Johnson, B.A.,Meliopoulos, V.A.,Ju, X.,Zhang, P.,Hughes, M.P.,Wu, J.,Koreski, K.P.,Chang, T.C.,Wu, G.,Hixon, J.,Duffner, J.,Wong, K.,Lemieux, R.,Lokugamage, K.G.,Alvardo, R.E.,Crocquet-Valdes, P.A.,Walker, D.H.,Plante, K.S.,Plante, J.A.,Weaver, S.C.,Kim, H.J.,Meyers, R.,Schultz-Cherry, S.,Ding, Q.,Menachery, V.D.,Taylor, J.P. Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication. Biorxiv 2023 0 0 0 8IQN Crystal structure of the human vitamin D receptor ligand binding domain complexed with 24,24-F2-25(OH)D3 2023-03-17 2024-03-27 Kakuda, S. Crystal structure of the human vitamin D receptor ligand binding domain complexed with 24,24-F2-25(OH)D3 To Be Published 0 0 0 0 8IQT Crystal structure of the human vitamin D receptor ligand binding domain complexed with (23R)-F-25(OH)D3 2023-03-17 2024-03-27 Kakuda, S. Crystal structure of the human vitamin D receptor ligand binding domain complexed with (23R)-F-25(OH)D3 To Be Published 0 0 0 0 8U4W 38482564 The crystal structure of a helical domain deleted PARP1 in complex with isoindolinone based inhibitor. 2023-09-11 2024-03-27 McCarthy, K.A.,Marcotte, D.J.,Parelkar, S.,McKinnon, C.L.,Trammell, L.E.,Stangeland, E.L.,Jetson, R.R. Discovery of Potent Isoindolinone Inhibitors That Target an Active Conformation of PARP1 Using DNA-Encoded Libraries. Chemmedchem 2024 0 0 0