PDB_ID	PUBMED_CID	STRUCTURE TITLE	DEPOSITION DATE	RELEASE DATE	AUTHORS	CITATION TITLE	JOURNAL	YEAR	VOLUME	FIRST PAGE	LAST PAGE
1DPG		GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES	1995-12-04	1996-03-08	Rowland, P.,Basak, A.K.,Gover, S.,Levy, H.R.,Adams, M.J.	The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 A resolution.	Structure	1994	2	1073	1087	
1PEA		AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH ACETAMIDE	1995-11-16	1996-04-03	Pearl, L.,O'Hara, B.,Drew, R.,Wilson, S.	Crystal structure of AmiC: the controller of transcription antitermination in the amidase operon of Pseudomonas aeruginosa.	EMBO J.	1994	13	5810	5817	
1ELP	15299634	GAMMA-D CRYSTALLIN STRUCTURE AT 1.95 A RESOLUTION	1995-12-20	1996-06-10	Chirgadze, Y.N.,Driessen, H.P.,Wright, G.,Slingsby, C.,Hay, R.E.,Lindley, P.F.	Structure of bovine eye lens gammaD (gammaIIIb)-crystallin at 1.95 A.	Acta Crystallogr.,Sect.D	1996	52	712	721	
1VID		CATECHOL O-METHYLTRANSFERASE	1996-01-05	1996-07-11	Vidgren, J.,Svensson, L.A.,Liljas, A.	Crystal structure of catechol O-methyltransferase.	Nature	1994	368	354	358	
1NOI		COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES	1996-03-12	1996-08-01	Mitchell, E.P.,Withers, S.G.,Ermert, P.,Vasella, A.T.,Garman, E.F.,Oikonomakos, N.G.,Johnson, L.N.	Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.	Biochemistry	1996	35	7341	7355	
1PTU		CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)	1995-04-21	1996-08-01	Jia, Z.,Barford, D.,Flint, A.J.,Tonks, N.K.	Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.	Science	1995	268	1754	1758	
242D	16702655	MAD PHASING STRATEGIES EXPLORED WITH A BROMINATED OLIGONUCLEOTIDE CRYSTAL AT 1.65 A RESOLUTION.	1996-06-20	1996-09-19	Peterson, M.R.,Harrop, S.J.,McSweeney, S.M.,Leonard, G.A.,Thompson, A.W.,Hunter, W.N.,Helliwell, J.R.	MAD Phasing Strategies Explored with a Brominated Oligonucleotide Crystal at 1.65A Resolution.	J.Synchrotron Radiat.	1996	3	24	34	
1LEH		LEUCINE DEHYDROGENASE FROM BACILLUS SPHAERICUS	1995-06-09	1996-12-23	Baker, P.J.,Turnbull, A.P.,Sedelnikova, S.E.,Stillman, T.J.,Rice, D.W.	A role for quaternary structure in the substrate specificity of leucine dehydrogenase.	Structure	1995	3	693	705	
1STE		STAPHYLOCOCCAL ENTEROTOXIN C2 FROM STAPHYLOCOCCUS AUREUS	1995-08-21	1996-12-23	Papageorgiou, A.C.,Acharya, K.R.,Shapiro, R.,Passalacqua, E.F.,Brehm, R.D.,Tranter, H.S.	Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site.	Structure	1995	3	769	779	
1EXT		EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.	1996-07-03	1997-01-11	Naismith, J.H.,Devine, T.Q.,Kohno, T.,Sprang, S.R.	Structures of the extracellular domain of the type I tumor necrosis factor receptor.	Structure	1996	4	1251	1262	
1GTM		STRUCTURE OF GLUTAMATE DEHYDROGENASE	1996-08-22	1997-01-11	Yip, K.S.,Stillman, T.J.,Britton, K.L.,Artymiuk, P.J.,Baker, P.J.,Sedelnikova, S.E.,Engel, P.C.,Pasquo, A.,Chiaraluce, R.,Consalvi, V.,Scandurra, R.,Rice, D.W.	The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.	Structure	1995	3	1147	1158	
1PFR		RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN	1996-12-03	1997-03-12	Logan, D.T.,Su, X.D.,Aberg, A.,Regnstrom, K.,Hajdu, J.,Eklund, H.,Nordlund, P.	Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.	Structure	1996	4	1053	1064	
1RCO		SPINACH RUBISCO IN COMPLEX WITH THE INHIBITOR D-XYLULOSE-2,2-DIOL-1,5-BISPHOSPHATE	1996-10-31	1997-03-12	Taylor, T.C.,Fothergill, M.D.,Andersson, I.	A common structural basis for the inhibition of ribulose 1,5-bisphosphate carboxylase by 4-carboxyarabinitol 1,5-bisphosphate and xylulose 1,5-bisphosphate.	J.Biol.Chem.	1996	271	32894	32899	
2TPL		TYROSINE PHENOL-LYASE FROM CITROBACTER INTERMEDIUS COMPLEX WITH 3-(4'-HYDROXYPHENYL)PROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE AND CS+ ION	1997-01-23	1997-04-01	Sundararaju, B.,Antson, A.A.,Phillips, R.S.,Demidkina, T.V.,Barbolina, M.V.,Gollnick, P.,Dodson, G.G.,Wilson, K.S.	The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.	Biochemistry	1997	36	6502	6510	
1RCX		NON-ACTIVATED SPINACH RUBISCO IN COMPLEX WITH ITS SUBSTRATE RIBULOSE-1,5-BISPHOSPHATE	1996-12-06	1997-06-16	Taylor, T.C.,Andersson, I.	The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate.	J.Mol.Biol.	1997	265	432	444	
1AA1		ACTIVATED SPINACH RUBISCO IN COMPLEX WITH THE PRODUCT 3-PHOSPHOGLYCERATE	1997-01-20	1997-07-07	Taylor, T.C.,Andersson, I.	Structure of a product complex of spinach ribulose-1,5-bisphosphate carboxylase/oxygenase.	Biochemistry	1997	36	4041	4046	
1NDS	15299906	CRYSTALLOGRAPHIC STRUCTURE OF A SUBSTRATE BOUND BLUE COPPER NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS	1997-01-23	1997-07-07	Dodd, F.E.,Hasnain, S.S.,Abraham, Z.H.,Eady, R.R.,Smith, B.E.	Structures of a blue-copper nitrite reductase and its substrate-bound complex.	Acta Crystallogr.,Sect.D	1997	53	406	418	
1ZEN		CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE	1996-07-08	1997-07-07	Cooper, S.J.,Leonard, G.A.,McSweeney, S.M.,Thompson, A.W.,Naismith, J.H.,Qamar, S.,Plater, A.,Berry, A.,Hunter, W.N.	The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.	Structure	1996	4	1303	1315	
1RKM		STRUCTURE OF OPPA	1997-03-25	1997-07-29	Sleigh, S.H.,Tame, J.R.,Dodson, E.J.,Wilkinson, A.J.	Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine.	Biochemistry	1997	36	9747	9758	
2RKM		STRUCTURE OF OPPA COMPLEXED WITH LYS-LYS	1997-03-25	1997-07-29	Sleigh, S.H.,Tame, J.R.,Dodson, E.J.,Wilkinson, A.J.	Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine.	Biochemistry	1997	36	9747	9758	
1GOW		BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS	1996-09-19	1997-08-20	Aguilar, C.F.,Sanderson, I.,Moracci, M.,Ciaramella, M.,Nucci, R.,Rossi, M.,Pearl, L.H.	Crystal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability.	J.Mol.Biol.	1997	271	789	802	
1AEW		L-CHAIN HORSE APOFERRITIN	1997-02-26	1997-09-04	Hempstead, P.D.,Yewdall, S.J.,Fernie, A.R.,Lawson, D.M.,Artymiuk, P.J.,Rice, D.W.,Ford, G.C.,Harrison, P.M.	Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution.	J.Mol.Biol.	1997	268	424	448	
1DAN		Complex of active site inhibited human blood coagulation factor VIIA with human recombinant soluble tissue factor	1997-03-05	1997-09-04	Banner, D.W.,D'Arcy, A.,Chene, C.,Winkler, F.K.,Guha, A.,Konigsberg, W.H.,Nemerson, Y.,Kirchhofer, D.	The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.	Nature	1996	380	41	46	
1AJX		HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC UREA INHIBITOR AHA001	1997-05-11	1997-09-17	Backbro, K.,Lowgren, S.,Osterlund, K.,Atepo, J.,Unge, T.,Hulten, J.,Bonham, N.M.,Schaal, W.,Karlen, A.,Hallberg, A.	Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor.	J.Med.Chem.	1997	40	898	902	
1AH5	10089459	REDUCED FORM SELENOMETHIONINE-LABELLED HYDROXYMETHYLBILANE SYNTHASE DETERMINED BY MAD	1997-04-13	1997-10-15	Hadener, A.,Matzinger, P.K.,Battersby, A.R.,McSweeney, S.,Thompson, A.W.,Hammersley, A.P.,Harrop, S.J.,Cassetta, A.,Deacon, A.,Hunter, W.N.,Nieh, Y.P.,Raftery, J.,Hunter, N.,Helliwell, J.R.	Determination of the structure of seleno-methionine-labelled hydroxymethylbilane synthase in its active form by multi-wavelength anomalous dispersion.	Acta Crystallogr.,Sect.D	1999	55	631	643	
1AOF		CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED FORM	1997-07-02	1997-10-15	Williams, P.A.,Fulop, V.,Garman, E.F.,Saunders, N.F.,Ferguson, S.J.,Hajdu, J.	Haem-ligand switching during catalysis in crystals of a nitrogen-cycle enzyme.	Nature	1997	389	406	412	
1AH8		STRUCTURE OF THE ORTHORHOMBIC FORM OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE	1997-04-14	1997-10-22	Prodromou, C.,Roe, S.M.,Piper, P.W.,Pearl, L.H.	A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone.	Nat.Struct.Biol.	1997	4	477	482	
352D		THE CRYSTAL STRUCTURE OF A PARALLEL-STRANDED PARALLEL-STRANDED GUANINE TETRAPLEX AT 0.95 ANGSTROM RESOLUTION	1997-09-04	1997-11-10	Phillips, K.,Dauter, Z.,Murchie, A.I.,Lilley, D.M.,Luisi, B.	The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution.	J.Mol.Biol.	1997	273	171	182	
1CG2		CARBOXYPEPTIDASE G2	1996-12-20	1997-12-24	Rowsell, S.,Pauptit, R.A.,Tucker, A.D.,Melton, R.G.,Blow, D.M.,Brick, P.	Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.	Structure	1997	5	337	347	
1AOM		SUBSTRATE AND PRODUCT BOUND TO CYTOCHROME CD1 NITRITE REDUCTASE	1997-07-08	1998-02-04	Williams, P.A.,Fulop, V.,Garman, E.F.,Saunders, N.F.,Ferguson, S.J.,Hajdu, J.	Haem-ligand switching during catalysis in crystals of a nitrogen-cycle enzyme.	Nature	1997	389	406	412	
1AUK		HUMAN ARYLSULFATASE A	1997-08-29	1998-03-04	Lukatela, G.,Krauss, N.,Theis, K.,Selmer, T.,Gieselmann, V.,von Figura, K.,Saenger, W.	Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis.	Biochemistry	1998	37	3654	3664	
1AUP		GLUTAMATE DEHYDROGENASE	1997-09-01	1998-03-18	Baker, P.J.,Waugh, M.L.,Wang, X.G.,Stillman, T.J.,Turnbull, A.P.,Engel, P.C.,Rice, D.W.	Determinants of substrate specificity in the superfamily of amino acid dehydrogenases.	Biochemistry	1997	36	16109	16115	
1DMR		OXIDIZED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS	1997-04-22	1998-03-18	Mcalpine, A.S.,Mcewan, A.G.,Shaw, A.,Bailey, S.	Molybdenum Active Centre of Dmso Reductase from Rhodobacter Capsulatus: Crystal Structure of the Oxidised Enzyme at 1.82-A Resolution and the Dithionite-Reduced Enzyme at 2.8-A Resolution	J.Biol.Inorg.Chem.	1997	2	690	701	
2DMR		DITHIONITE REDUCED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS	1997-04-24	1998-03-18	Mcalpine, A.S.,Mcewan, A.G.,Shaw, A.,Bailey, S.	Molybdenum Active Centre of Dmso Reductase from Rhodobacter Capsulatus: Crystal Structure of the Oxidised Enzyme at 1.82-A Resolution and the Dithionite-Reduced Enzyme at 2.8-A Resolution	J.Biol.Inorg.Chem.	1997	2	690	0	
3DMR		STRUCTURE OF DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS AT PH 7.0	1997-04-25	1998-03-18	Mcalpine, A.S.,Mcewan, A.G.,Shaw, A.,Bailey, S.	Molybdenum Active Centre of Dmso Reductase from Rhodobacter Capsulatus: Crystal Structure of the Oxidised Enzyme at 1.82-A Resolution and the Dithionite-Reduced Enzyme at 2.8-A Resolution	J.Biol.Inorg.Chem.	1997	2	690	0	
1GUK		CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4	1997-12-11	1998-04-08	Krengel, U.,Schroter, K.H.,Hoier, H.,Arkema, A.,Kalk, K.H.,Zimniak, P.,Dijkstra, B.W.	Crystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stress.	FEBS Lett.	1998	422	285	290	
2MSP		MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5	1997-12-19	1998-04-15	Bullock, T.L.,McCoy, A.J.,Kent, H.M.,Roberts, T.M.,Stewart, M.	Structural basis for amoeboid motility in nematode sperm.	Nat.Struct.Biol.	1998	5	184	189	
1AZL		G61V FLAVODOXIN MUTANT FROM DESULFOVIBRIO VULGARIS	1997-11-18	1998-05-20	O'Farrell, P.A.,Walsh, M.A.,McCarthy, A.A.,Higgins, T.M.,Voordouw, G.,Mayhew, S.G.	Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.	Biochemistry	1998	37	8405	8416	
1AKT		G61N OXIDIZED FLAVODOXIN MUTANT	1997-05-27	1998-05-27	O'Farrell, P.A.,Walsh, M.A.,McCarthy, A.A.,Higgins, T.M.,Voordouw, G.,Mayhew, S.G.	Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.	Biochemistry	1998	37	8405	8416	
1A0C		XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES	1997-11-28	1998-06-03	Gallay, O.,Chopra, R.,Conti, E.,Brick, P.,Jackson, R.,Hartley, B.,Vieille, C.,Zeikus, J.G.,Blow, D.	Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile	To be Published	0	0	0	0	
1A8Z		STRUCTURE DETERMINATION OF A 16.8KDA COPPER PROTEIN RUSTICYANIN AT 2.1A RESOLUTION USING ANOMALOUS SCATTERING DATA WITH DIRECT METHODS	1998-03-30	1998-06-17	Harvey, I.,Hao, Q.,Duke, E.M.,Ingledew, W.J.,Hasnain, S.S.	Structure determination of a 16.8 kDa copper protein at 2.1 A resolution using anomalous scattering data with direct methods.	Acta Crystallogr.,Sect.D	1998	54	629	635	
1BB9		CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2	1998-04-29	1998-06-17	Owen, D.J.,Wigge, P.,Vallis, Y.,Moore, J.D.,Evans, P.R.,McMahon, H.T.	Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.	EMBO J.	1998	17	5273	5285	
1AM1		ATP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE	1997-06-20	1998-06-24	Prodromou, C.,Roe, S.M.,O'Brien, R.,Ladbury, J.E.,Piper, P.W.,Pearl, L.H.	Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone	Cell(Cambridge,Mass.)	1997	90	65	75	
1AMW		ADP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE	1997-06-19	1998-06-24	Prodromou, C.,Roe, S.M.,O'Brien, R.,Ladbury, J.E.,Piper, P.W.,Pearl, L.H.	Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone	Cell(Cambridge,Mass.)	1997	90	65	75	
2DPG		COMPLEX OF INACTIVE MUTANT (H240->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES WITH NADP+	1998-04-17	1998-07-15	Cosgrove, M.S.,Naylor, C.,Paludan, S.,Adams, M.J.,Levy, H.R.	On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase.	Biochemistry	1998	37	2759	2767	
1BN8		BACILLUS SUBTILIS PECTATE LYASE	1998-07-31	1998-08-05	Pickersgill, R.,Jenkins, J.,Harris, G.,Nasser, W.,Robert-Baudouy, J.	The structure of Bacillus subtilis pectate lyase in complex with calcium.	Nat.Struct.Biol.	1994	1	717	723	
1A54		PHOSPHATE-BINDING PROTEIN MUTANT A197C LABELLED WITH A COUMARIN FLUOROPHORE AND BOUND TO DIHYDROGENPHOSPHATE ION	1998-02-19	1998-10-14	Hirshberg, M.,Henrick, K.,Haire, L.L.,Vasisht, N.,Brune, M.,Corrie, J.E.,Webb, M.R.	Crystal structure of phosphate binding protein labeled with a coumarin fluorophore, a probe for inorganic phosphate.	Biochemistry	1998	37	10381	10385	
1BGV		GLUTAMATE DEHYDROGENASE	1998-06-01	1998-10-14	Stillman, T.J.,Baker, P.J.,Britton, K.L.,Rice, D.W.	Conformational flexibility in glutamate dehydrogenase. Role of water in substrate recognition and catalysis.	J.Mol.Biol.	1993	234	1131	1139	
1DFX		DESULFOFERRODOXIN FROM DESULFOVIBRIO DESULFURICANS, ATCC 27774	1997-09-03	1998-10-14	Coelho, A.V.,Matias, P.,Fulop, V.,Thompson, A.,Gonzalez, A.,Carrondo, M.A.	Desulfoferrodoxin Structure Determined by MAD Phasing and Refinement to 1.9 Angstroms Resolution Reveals a Unique Combination of a Tetrahedral Fes4 Centre with a Square Pyramidal Fesn4 Centre	J.Biol.Inorg.Chem.	1997	2	680	0	
1BJ5		HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID	1998-07-02	1998-11-04	Curry, S.,Mandelkow, H.,Brick, P.,Franks, N.	Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.	Nat.Struct.Biol.	1998	5	827	835	
1NDT		NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS	1998-10-28	1998-11-04	Dodd, F.E.,Van Beeumen, J.,Eady, R.R.,Hasnain, S.S.	X-ray structure of a blue-copper nitrite reductase in two crystal forms. The nature of the copper sites, mode of substrate binding and recognition by redox partner.	J.Mol.Biol.	1998	282	369	382	
4GAL		CRYSTAL STRUCTURE OF HUMAN GALECTIN-7 IN COMPLEX WITH LACTOSE	1998-07-13	1998-11-04	Leonidas, D.D.,Vatzaki, E.H.,Vorum, H.,Celis, J.E.,Madsen, P.,Acharya, K.R.	Structural basis for the recognition of carbohydrates by human galectin-7.	Biochemistry	1998	37	13930	13940	
1BA3		FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM	1998-04-21	1998-11-11	Franks, N.P.,Jenkins, A.,Conti, E.,Lieb, W.R.,Brick, P.	Structural basis for the inhibition of firefly luciferase by a general anesthetic.	Biophys.J.	1998	75	2205	2211	
2SHK	15299895	THE THREE-DIMENSIONAL STRUCTURE OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI COMPLEXED WITH ADP	1997-10-27	1998-11-18	Krell, T.,Coyle, J.E.,Horsburgh, M.J.,Coggins, J.R.,Lapthorn, A.J.	Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.	Acta Crystallogr.,Sect.D	1997	53	612	614	
1AYR		ARRESTIN FROM BOVINE ROD OUTER SEGMENTS	1997-11-10	1998-11-25	Granzin, J.,Wilden, U.,Choe, H.W.,Labahn, J.,Krafft, B.,Buldt, G.	X-ray crystal structure of arrestin from bovine rod outer segments.	Nature	1998	391	918	921	
1AKQ	12206666	D95A OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS	1997-03-27	1998-12-02	McCarthy, A.A.,Walsh, M.A.,Verma, C.S.,O'Connell, D.P.,Reinhold, M.,Yalloway, G.N.,D'Arcy, D.,Higgins, T.M.,Voordouw, G.,Mayhew, S.G.	Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.	Biochemistry	2002	41	10950	10962	
1B38	10085115	HUMAN CYCLIN-DEPENDENT KINASE 2	1998-12-17	1998-12-23	Brown, N.R.,Noble, M.E.,Lawrie, A.M.,Morris, M.C.,Tunnah, P.,Divita, G.,Johnson, L.N.,Endicott, J.A.	Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.	J.Biol.Chem.	1999	274	8746	8756	
1BG6		CRYSTAL STRUCTURE OF THE N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE FROM ARTHROBACTER SP. STRAIN 1C	1998-06-05	1999-01-13	Britton, K.L.,Asano, Y.,Rice, D.W.	Crystal structure and active site location of N-(1-D-carboxylethyl)-L-norvaline dehydrogenase.	Nat.Struct.Biol.	1998	5	593	601	
1BHD		SECOND CALPONIN HOMOLOGY DOMAIN FROM UTROPHIN	1998-06-05	1999-01-13	Keep, N.H.,Norwood, F.L.,Moores, C.A.,Winder, S.J.,Kendrick-Jones, J.	The 2.0 A structure of the second calponin homology domain from the actin-binding region of the dystrophin homologue utrophin.	J.Mol.Biol.	1999	285	1257	1264	
1BJZ		TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION	1998-06-29	1999-01-13	Orth, P.,Saenger, W.,Hinrichs, W.	Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction.	Biochemistry	1999	38	191	198	
1NK1		NK1 FRAGMENT OF HUMAN HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR (HGF/SF) AT 2.5 ANGSTROM RESOLUTION	1998-08-20	1999-01-13	Chirgadze, D.Y.,Hepple, J.P.,Zhou, H.,Byrd, R.A.,Blundell, T.L.,Gherardi, E.	Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.	Nat.Struct.Biol.	1999	6	72	79	
2BTM	10383424	DOES THE HIS12-LYS13 PAIR PLAY A ROLE IN THE ADAPTATION OF THERMOPHILIC TIMS TO HIGH TEMPERATURES?	1999-01-04	1999-01-13	Alvarez, M.,Wouters, J.,Maes, D.,Mainfroid, V.,Rentier-Delrue, F.,Wyns, L.,Depiereux, E.,Martial, J.A.	Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperatures.	J.Biol.Chem.	1999	274	19181	19187	
1BEY		ANTIBODY TO CAMPATH-1H HUMANIZED FAB	1998-05-18	1999-01-27	Cheetham, G.M.,Hale, G.,Waldmann, H.,Bloomer, A.C.	Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.	J.Mol.Biol.	1998	284	85	99	
1K89		K89L MUTANT OF GLUTAMATE DEHYDROGENASE	1998-06-05	1999-01-27	Stillman, T.J.,Migueis, A.M.,Wang, X.G.,Baker, P.J.,Britton, K.L.,Engel, P.C.,Rice, D.W.	Insights into the mechanism of domain closure and substrate specificity of glutamate dehydrogenase from Clostridium symbiosum.	J.Mol.Biol.	1999	285	875	885	
1BU5		X-RAY CRYSTAL STRUCTURE OF THE DESULFOVIBRIO VULGARIS (HILDENBOROUGH) APOFLAVODOXIN-RIBOFLAVIN COMPLEX	1998-09-12	1999-02-09	Walsh, M.A.,McCarthy, A.,O'Farrell, P.A.,McArdle, P.,Cunningham, P.D.,Mayhew, S.G.,Higgins, T.M.	X-ray crystal structure of the Desulfovibrio vulgaris (Hildenborough) apoflavodoxin-riboflavin complex.	Eur.J.Biochem.	1998	258	362	371	
1ZEI		CROSS-LINKED B28 ASP INSULIN	1998-07-14	1999-02-16	Whittingham, J.L.,Edwards, D.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G.	Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.	Biochemistry	1998	37	11516	11523	
5PGM	10064712	SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE	1998-08-19	1999-02-16	Rigden, D.J.,Walter, R.A.,Phillips, S.E.,Fothergill-Gilmore, L.A.	Sulphate ions observed in the 2.12 A structure of a new crystal form of S. cerevisiae phosphoglycerate mutase provide insights into understanding the catalytic mechanism.	J.Mol.Biol.	1999	286	1507	1517	
1CB4	10092461	CRYSTAL STRUCTURE OF COPPER, ZINC SUPEROXIDE DISMUTASE	1999-02-26	1999-03-03	Hough, M.A.,Hasnain, S.S.	Crystallographic structures of bovine copper-zinc superoxide dismutase reveal asymmetry in two subunits: functionally important three and five coordinate copper sites captured in the same crystal.	J.Mol.Biol.	1999	287	579	592	
1BFO		CAMPATH-1G IGG2B RAT MONOCLONAL FAB	1998-05-20	1999-03-16	Cheetham, G.M.,Hale, G.,Waldmann, H.,Bloomer, A.C.	Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.	J.Mol.Biol.	1998	284	85	99	
1B1J		CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT H13A.	1998-11-20	1999-04-02	Leonidas, D.D.,Shapiro, R.,Allen, S.C.,Subbarao, G.V.,Veluraja, K.,Acharya, K.R.	Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.	J.Mol.Biol.	1999	285	1209	1233	
2ANG		CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN OF THE MET(-1) FORM	1998-11-12	1999-04-02	Leonidas, D.D.,Shapiro, R.,Allen, S.C.,Subbarao, G.V.,Veluraja, K.,Acharya, K.R.	Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.	J.Mol.Biol.	1999	285	1209	1233	
1SBS		CRYSTAL STRUCTURE OF AN ANTI-HCG FAB	1998-04-08	1999-04-13	Fotinou, C.,Beauchamp, J.,Emsley, P.,deHaan, A.,Schielen, W.J.,Bos, E.,Isaacs, N.W.	Structure of an Fab fragment against a C-terminal peptide of hCG at 2.0 A resolution.	J.Biol.Chem.	1998	273	22515	22518	
1CA1		ALPHA-TOXIN FROM CLOSTRIDIUM PERFRINGENS	1998-04-22	1999-05-04	Naylor, C.E.,Eaton, J.T.,Howells, A.,Justin, N.,Moss, D.S.,Titball, R.W.,Basak, A.K.	Structure of the key toxin in gas gangrene.	Nat.Struct.Biol.	1998	5	738	746	
1CBF		THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF	1998-05-01	1999-05-11	Schubert, H.L.,Wilson, K.S.,Raux, E.,Woodcock, S.C.,Warren, M.J.	The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase.	Nat.Struct.Biol.	1998	5	585	592	
2DHQ	10360352	3-DEHYDROQUINATE DEHYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS	1999-01-29	1999-05-27	Gourley, D.G.,Shrive, A.K.,Polikarpov, I.,Krell, T.,Coggins, J.R.,Hawkins, A.R.,Isaacs, N.W.,Sawyer, L.	The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.	Nat.Struct.Biol.	1999	6	521	525	
1PJB		L-ALANINE DEHYDROGENASE	1998-06-05	1999-06-08	Baker, P.J.,Sawa, Y.,Shibata, H.,Sedelnikova, S.E.,Rice, D.W.	Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.	Nat.Struct.Biol.	1998	5	561	567	
1SAY		L-ALANINE DEHYDROGENASE COMPLEXED WITH PYRUVATE	1998-06-05	1999-06-08	Baker, P.J.,Sawa, Y.,Shibata, H.,Sedelnikova, S.E.,Rice, D.W.	Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.	Nat.Struct.Biol.	1998	5	561	567	
1QHF	10531478	YEAST PHOSPHOGLYCERATE MUTASE-3PG COMPLEX STRUCTURE TO 1.7 A	1999-05-13	1999-06-10	Crowhurst, G.S.,Dalby, A.R.,Isupov, M.N.,Campbell, J.W.,Littlechild, J.A.	Structure of a phosphoglycerate mutase:3-phosphoglyceric acid complex at 1.7 A.	Acta Crystallogr.,Sect.D	1999	55	1822	1826	
1PJC		L-ALANINE DEHYDROGENASE COMPLEXED WITH NAD	1998-06-05	1999-07-15	Baker, P.J.,Sawa, Y.,Shibata, H.,Sedelnikova, S.E.,Rice, D.W.	Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.	Nat.Struct.Biol.	1998	5	561	567	
1B2P	10393293	NATIVE MANNOSE-SPECIFIC BULB LECTIN FROM SCILLA CAMPANULATA (BLUEBELL) AT 1.7 ANGSTROMS RESOLUTION	1998-11-30	1999-07-22	Wood, S.D.,Wright, L.M.,Reynolds, C.D.,Rizkallah, P.J.,Allen, A.K.,Peumans, W.J.,Van Damme, E.J.	Structure of the native (unligated) mannose-specific bulb lectin from Scilla campanulata (bluebell) at 1.7 A resolution.	Acta Crystallogr.,Sect.D	1999	55	1264	1272	
1MJO	10986458	METHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT	1998-01-28	1999-08-02	Garvie, C.W.,Phillips, S.E.	Direct and indirect readout in mutant Met repressor-operator complexes.	Structure Fold.Des.	2000	8	905	914	
1QAL	10387067	THE ACTIVE SITE BASE CONTROLS COFACTOR REACTIVITY IN ESCHERICHIA COLI AMINE OXIDASE : X-RAY CRYSTALLOGRAPHIC STUDIES WITH MUTATIONAL VARIANTS	1999-03-19	1999-08-24	Murray, J.M.,Saysell, C.G.,Wilmot, C.M.,Tambyrajah, W.S.,Jaeger, J.,Knowles, P.F.,Phillips, S.E.,McPherson, M.J.	The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants.	Biochemistry	1999	38	8217	8227	
1BVU	10547290	GLUTAMATE DEHYDROGENASE FROM THERMOCOCCUS LITORALIS	1999-07-20	1999-09-18	Britton, K.L.,Yip, K.S.,Sedelnikova, S.E.,Stillman, T.J.,Adams, M.W.,Ma, K.,Maeder, D.L.,Robb, F.T.,Tolliday, N.,Vetriani, C.,Rice, D.W.,Baker, P.J.	Structure determination of the glutamate dehydrogenase from the hyperthermophile Thermococcus litoralis and its comparison with that from Pyrococcus furiosus	J.Mol.Biol.	1999	293	1121	1132	
1D6Z	10576737	CRYSTAL STRUCTURE OF THE AEROBICALLY FREEZE TRAPPED RATE-DETERMINING CATALYTIC INTERMEDIATE OF E. COLI COPPER-CONTAINING AMINE OXIDASE.	1999-10-16	2000-02-02	Wilmot, C.M.,Hajdu, J.,McPherson, M.J.,Knowles, P.F.,Phillips, S.E.	Visualization of dioxygen bound to copper during enzyme catalysis.	Science	1999	286	1724	1728	
1QMT	10606511	Recombinant Human Eosinophil Cationic Protein	1999-10-06	2000-02-04	Boix, E.,Leonidas, D.D.,Nikolovski, Z.,Nogues, M.V.,Cuchillo, C.M.,Acharya, K.R.	The Crystal Structure of Eosinophil Cationic Protein at 2.4 A Resolution	Biochemistry	1999	38	16794	0	
1QKZ	10512717	Fab fragment (MN14C11.6) in complex with a peptide antigen derived from Neisseria meningitidis P1.7 serosubtype antigen and domain II from Streptococcal protein G	1999-08-17	2000-02-06	Derrick, J.P.,Feavers, I.M.,Maiden, M.C.J.	Crystal Structure of an Fab Fragment in Complex with a Meningococcal Serosubtype Antigen and a Protein G Domain	J.Mol.Biol.	1999	293	81	0	
1DLP	10683433	STRUCTURAL CHARACTERIZATION OF THE NATIVE FETUIN-BINDING PROTEIN SCILLA CAMPANULATA AGGLUTININ (SCAFET): A NOVEL TWO-DOMAIN LECTIN	1999-12-11	2000-02-10	Wright, L.M.,Reynolds, C.D.,Rizkallah, P.J.,Allen, A.K.,Van Damme, E.J.,Donovan, M.J.,Peumans, W.J.	Structural characterisation of the native fetuin-binding protein Scilla campanulata agglutinin: a novel two-domain lectin.	FEBS Lett.	2000	468	19	22	
1CDZ		BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1	1999-03-04	2000-02-28	Zhang, X.,Morera, S.,Bates, P.A.,Whitehead, P.C.,Coffer, A.I.,Hainbucher, K.,Nash, R.A.,Sternberg, M.J.,Lindahl, T.,Freemont, P.S.	Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.	EMBO J.	1998	17	6404	6411	
1D0Q	10745010	STRUCTURE OF THE ZINC-BINDING DOMAIN OF BACILLUS STEAROTHERMOPHILUS DNA PRIMASE	1999-09-14	2000-03-29	Pan, H.,Wigley, D.B.	Structure of the zinc-binding domain of Bacillus stearothermophilus DNA primase.	Structure Fold.Des.	2000	8	231	239	
1DQD	10771426	CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR	2000-01-04	2000-05-10	Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P.	Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor.	Acta Crystallogr.,Sect.D	2000	56	573	580	
1DRY	10655615	CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND N-ALPHA-L-ACETYL ARGININE	2000-01-06	2000-07-06	Zhang, Z.,Ren, J.,Stammers, D.K.,Baldwin, J.E.,Harlos, K.,Schofield, C.J.	Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.	Nat.Struct.Biol.	2000	7	127	133	
1EHV	10884351	A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE	2000-02-23	2000-07-14	Johansson, E.,Parkinson, G.,Neidle, S.	A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure.	J.Mol.Biol.	2000	300	551	561	
2PVA	10331865	OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS	1998-11-13	2000-07-26	Suresh, C.G.,Pundle, A.V.,SivaRaman, H.,Rao, K.N.,Brannigan, J.A.,McVey, C.E.,Verma, C.S.,Dauter, Z.,Dodson, E.J.,Dodson, G.G.	Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members.	Nat.Struct.Biol.	1999	6	414	416	
1FQ4	11061973	CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A	2000-09-03	2000-09-20	Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B.	X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.	J.Mol.Biol.	2000	303	745	760	
1FQ5	11061973	X-ray structure of a cyclic statine inhibitor PD-129,541 bound to yeast proteinase A	2000-09-03	2000-09-20	Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B.	X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.	J.Mol.Biol.	2000	303	745	760	
1FQ6	11061973	X-RAY STRUCTURE OF GLYCOL INHIBITOR PD-133,450 BOUND TO SACCHAROPEPSIN	2000-09-03	2000-09-20	Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B.	X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.	J.Mol.Biol.	2000	303	745	760	
1FQ8	11061973	X-RAY STRUCTURE OF DIFLUOROSTATINE INHIBITOR CP81,198 BOUND TO SACCHAROPEPSIN	2000-09-04	2000-09-20	Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B.	X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.	J.Mol.Biol.	2000	303	745	760	
1E3B	11028014	CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3	2000-06-08	2000-10-22	Zou, J.,Taylor, P.,Dornan, J.,Robinson, S.P.,Walkinshaw, M.D.,Sadler, P.J.	First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine	Angew.Chem.Int.Ed.Engl.	2000	39	2931	0	
1E6D	11042110	PHOTOSYNTHETIC REACTION CENTER MUTANT WITH TRP M115 REPLACED WITH PHE (CHAIN M, WM115F) PHE M197 REPLACED WITH ARG (CHAIN M, FM197R)	2000-08-11	2000-10-30	Ridge, J.P.,Fyfe, P.K.,Mcauley, K.E.,Van Brederode, M.E.,Robert, B.,Van Grondelle, R.,Isaacs, N.W.,Cogdell, R.J.,Jones, M.R.	An Examination of How Structural Changes Can Affect the Rate of Electron Transfer in a Mutated Bacterial Photoreaction Centre	Biochem.J.	2000	351	567	0	
1QO5	11679716	Fructose 1,6-bisphosphate Aldolase from Human Liver Tissue	1999-11-03	2000-11-05	Dalby, A.R.,Tolan, D.R.,Littlechild, J.A.	The Structure of Human Liver Fructose-1,6-Bisphosphate Aldolase	Acta Crystallogr.,Sect.D	2001	57	1526	0	
1F6R	10896943	CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN	2000-06-23	2000-12-13	Chrysina, E.D.,Brew, K.,Acharya, K.R.	Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.	J.Biol.Chem.	2000	275	37021	37029	
1HQ3	12876341	CRYSTAL STRUCTURE OF THE HISTONE-CORE-OCTAMER IN KCL/PHOSPHATE	2000-12-14	2001-01-24	Chantalat, L.,Nicholson, J.M.,Lambert, S.J.,Reid, A.J.,Donovan, M.J.,Reynolds, C.D.,Wood, C.M.,Baldwin, J.P.	Structure of the histone-core octamer in KCl/phosphate crystals at 2.15 A resolution.	Acta Crystallogr.,Sect.D	2003	59	1395	1407	
1FZV	11069911	THE CRYSTAL STRUCTURE OF HUMAN PLACENTA GROWTH FACTOR-1 (PLGF-1), AN ANGIOGENIC PROTEIN AT 2.0A RESOLUTION	2000-10-04	2001-05-09	Iyer, S.,Leonidas, D.D.,Swaminathan, G.J.,Maglione, D.,Battisti, M.,Tucci, M.,Persico, M.G.,Acharya, K.R.	The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution.	J.Biol.Chem.	2001	276	12153	12161	
1E1V	10956187	HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR NU2058	2000-05-11	2001-05-10	Arris, C.E.,Boyle, F.T.,Calvert, A.H.,Curtin, N.J.,Endicott, J.A.,Garman, E.F.,Gibson, A.E.,Golding, B.T.,Grant, S.,Griffin, R.J.,Jewsbury, P.,Johnson, L.N.,Lawrie, A.M.,Newell, D.R.,Noble, M.E.M.,Sausville, E.A.,Schultz, R.,Yu, W.	Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles.	J.Med.Chem.	2000	43	2797	0	
1HI2	11154698	Eosinophil-derived Neurotoxin (EDN) - Sulphate Complex	2001-01-02	2001-05-31	Leonidas, D.D.,Boix, E.,Prill, R.,Suzuki, M.,Turton, R.,Minson, K.,Swaminathan, G.J.,Youle, R.J.,Acharya, K.R.	Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors	J.Biol.Chem.	2001	276	15009	0	
1E51		Crystal structure of native human erythrocyte 5-aminolaevulinic acid dehydratase	2000-07-13	2001-07-12	Mills-Davies, N.L.,Thompson, D.,Cooper, J.B.,Wood, S.P.,Shoolingin-Jordan, P.M.	The Crystal Structure of Human Ala-Dehydratase	To be Published	0	0	0	0	
1E5F		METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS	2000-07-25	2001-07-19	Goodall, G.,Mottram, J.C.,Coombs, G.H.,Lapthorn, A.J.	The Structure and Proposed Catalytic Mechanism of Methionine Gamma-Lyase	To be Published	0	0	0	0	
1EB7		Crystal structure of the di-haem cytochrome c peroxidase from Pseudomonas aeruginosa	2001-07-24	2001-07-24	Fulop, V.,Ridout, C.J.,Greenwood, C.,Hajdu, J.	Crystal Structure of the Di-Haemcytochrome C Peroxidase from Pseudomonas Aeruginosa	Structure	1995	3	1225	0	
1H52	11468363	Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by X-ray Crystallography	2001-05-18	2001-08-09	Leonidas, D.D.,Chavali, G.B.,Jardine, A.M.,Li, S.,Shapiro, R.,Acharya, K.R.	Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography	Protein Sci.	2001	10	1669	0	
1HBY	11468363	Binding of Phosphate and Pyrophosphate ions at the active site of human angiogenin as revealed by X-ray Crystallography	2001-04-21	2001-08-09	Leonidas, D.D.,Chavali, G.B.,Jardine, A.M.,Li, S.,Shapiro, R.,Acharya, K.R.	Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography	Protein Sci.	2001	10	1669	0	
1IGW	11526312	Crystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia coli	2001-04-18	2001-09-05	Britton, K.L.,Abeysinghe, I.S.,Baker, P.J.,Barynin, V.,Diehl, P.,Langridge, S.J.,McFadden, B.A.,Sedelnikova, S.E.,Stillman, T.J.,Weeradechapon, K.,Rice, D.W.	The structure and domain organization of Escherichia coli isocitrate lyase.	Acta Crystallogr.,Sect.D	2001	57	1209	1218	
1GN6		G152A mutant of Mycobacterium tuberculosis iron-superoxide dismutase.	2001-10-03	2001-10-05	Cooper, J.B.,Saward, S.,Erskine, P.T.,Badasso, M.O.,Wood, S.P.,Zhang, Y.,Young, D.B.	X-Ray Structure Analysis of an Engineered Fe-Superoxide Dismutase Gly-Ala Mutant with Significantly Reduced Stability to Denaturant	FEBS Lett.	1996	387	105	0	
1JRQ	11669617	X-ray Structure Analysis of the Role of the Conserved Tyrosine-369 in Active Site of E. coli Amine Oxidase	2001-08-14	2001-11-21	Murray, J.M.,Kurtis, C.R.,Tambyrajah, W.,Saysell, C.G.,Wilmot, C.M.,Parsons, M.R.,Phillips, S.E.,Knowles, P.F.,McPherson, M.J.	Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.	Biochemistry	2001	40	12808	12818	
1JME	11695889	Crystal Structure of Phe393His Cytochrome P450 BM3	2001-07-18	2001-11-23	Ost, T.W.,Munro, A.W.,Mowat, C.G.,Taylor, P.R.,Pesseguiero, A.,Fulco, A.J.,Cho, A.K.,Cheesman, M.A.,Walkinshaw, M.D.,Chapman, S.K.	Structural and spectroscopic analysis of the F393H mutant of flavocytochrome P450 BM3.	Biochemistry	2001	40	13430	13438	
1KCQ	11753432	Human Gelsolin Domain 2 with a Cd2+ bound	2001-11-09	2002-01-04	Kazmirski, S.L.,Isaacson, R.L.,An, C.,Buckle, A.,Johnson, C.M.,Daggett, V.,Fersht, A.R.	Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.	Nat.Struct.Biol.	2002	9	112	116	
1H76	11752780	The crystal structure of diferric porcine serum transferrin	2001-07-03	2002-01-15	Hall, D.R.,Hadden, J.M.,Leonard, G.A.,Bailey, S.,Neu, M.,Winn, M.,Lindley, P.F.	The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 And 2.60A, Respectively	Acta Crystallogr.,Sect.D	2002	58	70	0	
1GOZ	11704673	Structural basis for the altered T-cell receptor binding specificty in a superantigenic staphylococcus aureus Enterotoxin-B mutant	2001-10-29	2002-02-13	Baker, M.D.,Papageorgiou, A.C.,Titball, R.,Miller, J.,White, S.,Lingard, B.,Lee, J.,Cavanagh, D.,Kehoe, M.,Robinson, J.,Acharya, K.R.	Structural and Functional Role of Threonine 112 in a Superantigen Staphylococcus Aureus Enterotoxin B.	J.Biol.Chem.	2002	277	2756	0	
1GS7	11829502	Crystal structure of H254F mutant of Alcaligenes xylosoxidans Nitrite Reductase	2002-01-02	2002-02-14	Ellis, M.J.,Prudencio, M.,Dodd, F.E.,Strange, R.W.,Sawers, G.,Eady, R.R.,Hasnain, S.S.	Biochemical and Crystallographic Studies of the met144Ala, Asp92Asn and His254Phe Mutants of the Nitrite Reductase from Alcaligenes Xylosoxidans Provide Insight Into the Enzyme Mechanism.	J.Mol.Biol.	2002	316	51	0	
1K59	11851402	Crystal Structure of Human Angiogenin Variant Q117G	2001-10-10	2002-03-20	Leonidas, D.D.,Shapiro, R.,Subbarao, G.V.,Russo, A.,Acharya, K.R.	Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.	Biochemistry	2002	41	2552	2562	
1K5B	11851402	Crystal Structure of Human Angiogenin Variant des(121-123)	2001-10-10	2002-03-20	Leonidas, D.D.,Shapiro, R.,Subbarao, G.V.,Russo, A.,Acharya, K.R.	Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.	Biochemistry	2002	41	2552	2562	
1GXJ	11983169	SMC hinge domain from T. maritima w/o coiled coil	2002-04-07	2002-04-29	Haering, C.,Lowe, J.,Hochwagen, A.,Nasmyth, K.	Molecular Architecture of Smc Proteins and the Yeast Cohesin Complex	Mol.Cell	2002	9	773	0	
1GY2	12079384	Crystal structure of Met148Leu rusticyanin	2002-04-16	2002-05-23	Kanbi, L.D.,Antonyuk, S.,Hough, M.A.,Hall, J.F.,Dodd, F.,Hasnain, S.	Crystal Structures of the met148Leu and Ser86Asp Mutants of Rusticyanin from Thiobacillus Ferrooxidans: Insights Into the Structural Relationship with the Cupredoxins and the Multi Copper Proteins.	J.Mol.Biol.	2002	320	263	0	
1L5J	11992126	CRYSTAL STRUCTURE OF E. COLI ACONITASE B.	2002-03-07	2002-06-12	Williams, C.H.,Stillman, T.J.,Barynin, V.V.,Sedelnikova, S.E.,Tang, Y.,Green, J.,Guest, J.R.,Artymiuk, P.J.	E. coli aconitase B structure reveals a HEAT-like domain with implications for protein-protein recognition.	Nat.Struct.Biol.	2002	9	447	452	
1GXA	12054801	BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL AND PALMITIC ACID, TRIGONAL LATTICE Z	2002-04-01	2002-06-13	Kontopidis, G.,Holt, C.,Sawyer, L.	The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?	J.Mol.Biol.	2002	318	1043	0	
1GYG	12051905	R32 CLOSED FORM OF ALPHA-TOXIN FROM CLOSTRIDIUM PERFRINGENS STRAIN CER89L43	2002-04-23	2002-06-13	Eaton, J.T.,Naylor, C.,Howells, A.,Moss, D.,Titball, R.W.,Basak, A.K.	Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region	J.Mol.Biol.	2002	319	275	0	
1JI3	12417199	CRYSTAL STRUCTURE OF THE FIRST THERMOSTABLE BACTERIAL LIPASE FROM BACILLUS STEAROTHERMOPHILUS	2001-06-29	2002-11-01	Tyndall, J.D.A.,Sinchaikul, S.,Fothergill-Gilmore, L.A.,Taylor, P.,Walkinshaw, M.D.	Crystal Structure of a Thermostable Lipase from Bacillus stearothermophilus P1	J.Mol.Biol.	2002	323	859	869	
1H2N	12446723	Factor Inhibiting HIF-1 alpha	2002-08-12	2002-11-28	Elkins, J.M.,Hewitson, K.S.,McNeill, L.A.,Seibel, J.F.,Schlemminger, I.,Pugh, C.,Ratcliffe, P.,Schofield, C.J.	Structure of Factor-Inhibiting Hypoxia-Inducible Factor (Hif) Reveals Mechanism of Oxidative Modification of Hif-1Alpha	J.Biol.Chem.	2003	278	1802	1806	
1OE2	12691751	Atomic Resolution Structure of D92E Mutant of Alcaligenes xylosoxidans Nitrite Reductase	2003-03-18	2003-04-17	Ellis, M.J.,Dodd, F.E.,Sawers, G.,Eady, R.R.,Hasnain, S.S.	Atomic Resolution Structures of Native Copper Nitrite Reductase from Alcaligenes Xylosoxidans and the Active Site Mutant Asp92Glu	J.Mol.Biol.	2003	328	429	0	
1H4C	12719427	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA	2003-02-26	2003-05-08	Guse, A.,Stevenson, C.E.M.,Kuper, J.,Buchanan, G.,Schwarz, G.,Giordano, G.,Magalon, A.,Mendel, R.R.,Lawson, D.M.,Palmer, T.	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba	J.Biol.Chem.	2003	278	25302	0	
1H4D	12719427	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA	2003-02-26	2003-05-08	Guse, A.,Stevenson, C.E.M.,Kuper, J.,Buchanan, G.,Schwarz, G.,Giordano, G.,Magalon, A.,Mendel, R.R.,Lawson, D.M.,Palmer, T.	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba	J.Biol.Chem.	2003	278	25302	0	
1HJJ	12719427	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA	2003-02-27	2003-05-09	Guse, A.,Stevenson, C.E.M.,Kuper, J.,Buchanan, G.,Schwarz, G.,Giordano, G.,Magalon, A.,Mendel, R.R.,Lawson, D.M.,Palmer, T.	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba	J.Biol.Chem.	2003	278	25302	0	
1JYD	11604536	Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution	2001-09-12	2003-07-01	Greene, L.H.,Chrysina, E.D.,Irons, L.I.,Papageorgiou, A.C.,Acharya, K.R.,Brew, K.	Role of conserved residues in structure and stability: Tryptophans of human serum  retinol-binding protein, a model for the lipocalin superfamily	Protein Sci.	2001	10	2301	2316	
1GJO		The FGFr2 tyrosine kinase domain	2001-07-31	2003-08-15	Ceska, T.A.,Owens, R.,Doyle, C.,Hamlyn, P.,Crabbe, T.,Moffat, D.,Davis, J.,Martin, R.,Perry, M.J.	The Fgfr2 Tyrosine Kinase Domain	To be Published	0	0	0	0	
1OEJ	12909634	YodA from Escherichia coli crystallised with no added ions	2003-03-27	2003-08-15	David, G.,Blondeau, K.,Schiltz, M.,Penel, S.,Lewit-Bentley, A.	Yoda from Escherichia Coli is a Metal-Binding, Lipocalin-Like Protein	J.Biol.Chem.	2003	278	43728	0	
1UN9	12966101	Crystal structure of the dihydroxyacetone kinase from C. freundii in complex with AMP-PNP and Mg2+	2003-09-08	2003-10-30	Siebold, C.,Arnold, I.,Garcia-Alles, L.F.,Baumann, U.,Erni, B.	Crystal Structure of the Citrobacter Freundii Dihydroxyacetone Kinase Reveals an Eight-Stranded Alpha-Helical Barrel ATP-Binding Domain	J.Biol.Chem.	2003	278	48236	0	
1UNS	14559915	IDENTIFICATION OF A SECONDARY ZINC-BINDING SITE IN STAPHYLOCOCCAL ENTEROTOXIN C2: IMPLICATIONS FOR SUPERANTIGEN RECOGNITION	2003-09-15	2003-11-13	Papageorgiou, A.C.,Baker, M.D.,Mcleod, J.D.,Goda, S.,Manzotti, C.N.,Sanson, D.M.,Tranter, H.S.,Acharya, K.R.	Identification of a Secondary Zinc-Binding Site in Staphylococcal Enterotoxin C2: Implications for Superantigen Recognition	J.Biol.Chem.	2004	279	1297	0	
1UMX	14741581	PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ARG M267 REPLACED WITH LEU (CHAIN M, R267L)	2003-09-02	2004-06-29	Fyfe, P.K.,Isaacs, N.W.,Cogdell, R.J.,Jones, M.R.	Disruption of a specific molecular interaction with a bound lipid affects the thermal stability of the purple bacterial reaction centre.	Biochim.Biophys.Acta	2004	1608	11	22	
1W7O	15456779	cytochrome c3 from Desulfomicrobium baculatus	2004-09-07	2004-09-29	Correia, I.,Paquete, C.,Coelho, A.V.,Almeida, C.,Catarino, T.,Louro, R.,Frazao, C.,Saraiva, L.,Carrondo, M.A.,Turner, D.,Xavier, A.	Proton-Assisted Two-Electron Transfer in Natural Variants of Tetraheme Cytochromes from Desulfomicrobium Sp	J.Biol.Chem.	2004	279	52227	0	
1W27	15548745	Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum	2004-06-29	2004-11-25	Ritter, H.,Schulz, G.E.	Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase	Plant Cell	2004	16	3426	0	
2CAL	16503647	Crystal structure of His143Met rusticyanin	2005-12-21	2006-01-05	Barrett, M.L.,Harvey, I.,Sundararajan, M.,Surendran, R.,Hall, J.F.,Ellis, M.J.,Hough, M.A.,Strange, R.W.,Hillier, I.H.,Hasnain, S.S.	Atomic Resolution Crystal Structures, Exafs, and Quantum Chemical Studies of Rusticyanin and its Two Mutants Provide Insight Into its Unusual Properties.	Biochemistry	2006	45	2927	0	
2C57	16480265	H.pylori type II dehydroquinase in complex with FA1	2005-10-26	2006-02-22	Robinson, D.A.,Stewart, K.A.,Price, N.C.,Chalk, P.A.,Coggins, J.R.,Lapthorn, A.J.	Crystal Structures of Helicobacter Pylori Type II Dehydroquinase Inhibitor Complexes: New Directions for Inhibitor Design.	J.Med.Chem.	2006	49	1282	0	
2IXK	17046787	RmlC P aeruginosa with dTDP-4-keto rhamnnose (the product of the reaction)	2006-07-08	2006-08-14	Dong, C.,Major, L.L.,Srikannathasan, V.,Errey, J.C.,Giraud, M.F.,Lam, J.S.,Graninger, M.,Messner, P.,Mcneil, M.R.,Field, R.A.,Whitfield, C.,Naismith, J.H.	Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.	J.Mol.Biol.	2007	365	146	0	
2C7T	16894611	CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF BTRR, A DUAL FUNCTIONAL AMINOTRANSFERASE INVOLVED IN BUTIROSIN BIOSYNTHESIS.	2005-11-29	2006-08-16	Popovic, B.,Tang, X.,Chirgadze, D.Y.,Huang, F.,Blundell, T.L.,Spencer, J.B.	Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis.	Proteins	2006	65	220	230	
3UTL	22525752	Human pepsin 3b	2011-11-25	2011-12-14	Bailey, D.,Carpenter, E.P.,Coker, A.,Coker, S.,Read, J.,Jones, A.T.,Erskine, P.,Aguilar, C.F.,Badasso, M.,Toldo, L.,Rippmann, F.,Sanz-Aparicio, J.,Albert, A.,Blundell, T.L.,Roberts, N.B.,Wood, S.P.,Cooper, J.B.	An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.	Acta Crystallogr.,Sect.D	2012	68	541	552	
4GH4		Crystal Structure of Foot and Mouth Disease Virus A22 Serotype	2012-08-07	2013-02-20	Curry, S.,Fry, E.,Blakemore, W.,Abu-Ghazaleh, R.,Jackson, T.,King, A.,Lea, S.,Newman, J.,Rowlands, D.,Stuart, D.	Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.	Structure	1996	4	135	145	
4B6L		Discovery of Oral Polo-Like Kinase (PLK) Inhibitors with Enhanced Selectivity Profile using Residue Targeted Drug Design	2012-08-14	2013-08-21	Brown, K.,Charrier, J.D.,Durrant, S.,Griffiths, M.,Hudson, C.,Kay, D.,Knegtel, R.,Odonnell, M.,Pierard, F.,Twin, H.,Weber, P.,Young, S.	Discovery of Oral Polo-Like Kinase (Plk) Inhibitors with Enhanced Selectivity Profile Using Residue Targeted Drug Design	To be Published	0	0	0	0	
4PC1	26073967	Elongation Factor Tu:Ts complex with a bound phosphate	2014-04-14	2015-05-06	Thirup, S.S.,Van, L.B.,Nielsen, T.K.,Knudsen, C.R.	Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu.	J.Struct.Biol.	2015	191	10	21	
5HNR	28045381	The X-ray structure of octameric human native 5-aminolaevulinic acid dehydratase.	2016-01-18	2016-01-27	Mills-Davies, N.,Butler, D.,Norton, E.,Thompson, D.,Sarwar, M.,Guo, J.,Gill, R.,Azim, N.,Coker, A.,Wood, S.P.,Erskine, P.T.,Coates, L.,Cooper, J.B.,Rashid, N.,Akhtar, M.,Shoolingin-Jordan, P.M.	Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.	Acta Crystallogr D Struct Biol	2017	73	9	21	
6GE7	29879410	Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin	2018-04-25	2018-06-20	Rovoli, M.,Thireou, T.,Choiset, Y.,Haertle, T.,Sawyer, L.,Eliopoulos, E.,Kontopidis, G.	Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine beta-Lactoglobulin.	Int. J. Biol. Macromol.	2018	118	296	303