PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 5XH2 29235460 Crystal structure of a novel PET hydrolase R103G/S131A mutant in complex with pNP from Ideonella sakaiensis 201-F6 2017-04-19 2017-12-20 Han, X.,Liu, W.,Huang, J.W.,Ma, J.,Zheng, Y.,Ko, T.P.,Xu, L.,Cheng, Y.S.,Chen, C.C.,Guo, R.T. Structural insight into catalytic mechanism of PET hydrolase Nat Commun 2017 8 2106 2106 5XH3 29235460 Crystal structure of a novel PET hydrolase R103G/S131A mutant in complex with HEMT from Ideonella sakaiensis 201-F6 2017-04-19 2017-12-20 Han, X.,Liu, W.,Huang, J.W.,Ma, J.,Zheng, Y.,Ko, T.P.,Xu, L.,Cheng, Y.S.,Chen, C.C.,Guo, R.T. 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A structural model for (GlcNAc) 2 translocation via a periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria. J.Biol.Chem. 2021 297 101071 101071 6LZU 34400168 F411A mutant of chitin-specific solute binding protein from Vibrio harveyi co-crystalized with chitobiose. 2020-02-19 2021-02-24 Kitaoku, Y.,Fukamizo, T.,Kumsaoad, S.,Ubonbal, P.,Robinson, R.C.,Suginta, W. A structural model for (GlcNAc) 2 translocation via a periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria. J.Biol.Chem. 2021 297 101071 101071 6LZV 34400168 F437A mutant of chitin-specific solute binding protein from Vibrio harveyi co-crystalized with chitobiose. 2020-02-19 2021-02-24 Kitaoku, Y.,Fukamizo, T.,Kumsaoad, S.,Ubonbal, P.,Robinson, R.C.,Suginta, W. A structural model for (GlcNAc) 2 translocation via a periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria. 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Iscience 2021 24 102423 102423 7DEY 33884665 Structure of Dicer from Pichia stipitis 2020-11-05 2021-05-05 Chan, J.,Qinqin, F.,Jianwei, L.,Ying, C.,Machida, S.,Wei, C.,Yuan, Y.A.,Jobichen, C. Structural and mechanistic insight into stem-loop RNA processing by yeast Pichia stipitis Dicer. Protein Sci. 2021 30 1210 1220 7CMA 32828542 Structure of A151R from African swine fever virus Georgia 2020-07-26 2021-06-02 Huang, J.W.,Niu, D.,Liu, K.,Wang, Q.,Ma, L.,Chen, C.C.,Zhang, L.,Liu, W.,Zhou, S.,Min, J.,Wu, S.,Yang, Y.,Guo, R.T. Structure basis of non-structural protein pA151R from African Swine Fever Virus. Biochem.Biophys.Res.Commun. 2020 532 108 113 7CEB 34188035 Crystal structure of alpha6beta1 integrin headpiece 2020-06-22 2021-06-23 Arimori, T.,Miyazaki, N.,Mihara, E.,Takizawa, M.,Taniguchi, Y.,Cabanas, C.,Sekiguchi, K.,Takagi, J. Structural mechanism of laminin recognition by integrin. Nat Commun 2021 12 4012 4012 7CF7 Crystal Structure of YbeA CP74 W72F 2020-06-24 2021-06-30 Liu, C.Y.,Lai, C.H.,Hsu, S.T.D.,Lyu, P.C. Crystal Structure of YbeA CP74 W72F To Be Published 0 0 0 0 7CFY Crystal Structure of YbeA CP74 W48F 2020-06-29 2021-06-30 Liu, C.Y.,Lai, C.H.,Hsu, S.T.D.,Lyu, P.C. Crystal Structure of YbeA CP74 W48F To Be Published 0 0 0 0 7CIU Crystal Structure of Agmatine N-Acetyltransferase mutant S171A apo form 2020-07-08 2021-07-21 Chen, J.J.,Hu, I.C.,Lai, C.H.,Lyu, P.C. Crystal Structure of Agmatine N-Acetyltransferase mutant S171A To Be Published 0 0 0 0 7EHJ 34337952 human MTHFD2 in complex with compound 21, cofactor and phosphate. 2021-03-29 2021-08-11 Lee, L.C.,Peng, Y.H.,Chang, H.H.,Hsu, T.,Lu, C.T.,Huang, C.H.,Hsueh, C.C.,Kung, F.C.,Kuo, C.C.,Jiaang, W.T.,Wu, S.Y. Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2). 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Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa to be published 0 0 0 0 7CX1 Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine 2020-09-01 2021-09-01 Yu, X.,Gong, M.,Huang, J.,Liu, W.,Chen, C.,Guo, R. Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine to be published 0 0 0 0 7EBI 34400168 Chitin-specific solute binding protein from Vibrio harveyi co-crystalized with chitotetraose. 2021-03-09 2021-09-08 Kitaoku, Y.,Fukamizo, T.,Kumsaoad, S.,Ubonbal, P.,Robinson, R.C.,Suginta, W. A structural model for (GlcNAc) 2 translocation via a periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria. 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Crystallographic investigation and inhibition of Brugia malayi thymidylate synthase by a folate analog To Be Published 0 0 0 0 7DP5 Crystal structure of mutant V45A Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate 2020-12-18 2021-12-22 Keyunratsami, K.,Nualnoi, T.,Wongkamchai, S.,Songsiriritthigul, C.,Chen, C.-J.,Canyuk, B. Crystallographic investigation and inhibition of Brugia malayi thymidylate synthase by a folate analog To Be Published 0 0 0 0 7DP6 Crystal structure of mutant V45T Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate 2020-12-18 2021-12-22 Keyunratsami, K.,Nualnoi, T.,Wongkamchai, S.,Songsiriritthigul, C.,Chen, C.-J.,Canyuk, B. 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Acs Catalysis 2022 12 1945 1956 7EVB 35333570 Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 77% GTP/23% and 2 Na+ 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Sci Adv 2022 8 0 0 7EVC 35333570 Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 60% GTP/40% GDP and 2 Na+ 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Sci Adv 2022 8 0 0 7EVD 35333570 Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 53% GTP/47% and 2 Na+ 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Sci Adv 2022 8 0 0 7EVH 35333570 Odinarchaeota tubulin H393D mutant, in a psuedo protofilament arrangement, bound to 59% GDP, 41% phosphate 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Sci Adv 2022 8 0 0 7EVI 35333570 Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 79% GTP, 21% GDP, Na+, Mg2+ 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. Sci Adv 2022 8 0 0 7EVK 35333570 Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 78% GTP, 22% GDP, Na+ 2021-05-21 2022-03-23 Akil, C.,Ali, S.,Tran, L.T.,Gaillard, J.,Li, W.,Hayashida, K.,Hirose, M.,Kato, T.,Oshima, A.,Fujishima, K.,Blanchoin, L.,Narita, A.,Robinson, R.C. Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution. 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Commun Biol 2022 5 454 454 7VPW 35446349 Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724) 2021-10-18 2022-04-20 Yang, T.J.,Li, T.N.,Huang, R.S.,Pan, M.Y.,Lin, S.Y.,Lin, S.,Wu, K.P.,Wang, L.H.,Hsu, S.D. Tumor suppressor BAP1 nuclear import is governed by transportin-1. J.Cell Biol. 2022 221 0 0 7F2V 34403675 Urate oxidase from Thermobispora bispora in apo form 2021-06-14 2022-05-04 Chiu, Y.C.,Hsu, T.S.,Huang, C.Y.,Hsu, C.H. Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol. 2021 188 914 923 7VE4 35481641 C-terminal domain of VraR 2021-09-08 2022-05-18 Kumar, J.V.,Tseng, T.S.,Lou, Y.C.,Wei, S.Y.,Wu, T.H.,Tang, H.C.,Chiu, Y.C.,Hsu, C.H.,Chen, C. Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus. 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Structural insights into the cyclization of unusual brasilane-type sesquiterpenes. Int.J.Biol.Macromol. 2022 209 1784 1791 7EZB Thorarchaeota Rab bound to GDP 2021-06-01 2022-06-08 Robinson, R.C.,Tran, L.T. Structure of Thor-Rab To Be Published 0 0 0 0 7EZE Thorarchaeota Rab GTP-gamma-S/Mg2+ (soak) 2021-06-01 2022-06-08 Robinson, R.C.,Tran, L.T. Structure of Thor-Rab To Be Published 0 0 0 0 7VFT 35776134 Crystal structure of rGGGC(CAG)5GUCC oligo 2021-09-13 2022-06-15 An, Y.,Chen, Z.S.,Chan, H.Y.E.,Ngo, J.C.K. Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases. Nucleic Acids Res. 2022 50 7655 7668 7V40 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V41 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with toluene. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V42 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with benzyl-alcohol. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V43 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-chlorotoluene. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V44 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with meta-chlorotoluene. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V45 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-bromotoluene. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V46 Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with ortho-chlorotoluene. 2021-08-12 2022-06-22 Chen, C.C.,Dai, M.,Zhang, L.,Zhao, J.,Zeng, W.,Shi, M.,Huang, J.W.,Liu, W.,Guo, R.T.,Li, A. Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis 2022 12 2831 2839 7V5L 35467071 Crystal structure of human bleomycin hydrolase 2021-08-17 2022-06-29 Zheng, Y.Z.,Cui, J.,Wang, Y.L.,Huang, S.J.,Lin, E.C.,Huang, S.C.,Rudolf, J.D.,Yan, X.,Chang, C.Y. The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease. Chembiochem 2022 23 0 0 7XF9 35467071 Crystal structure of human bleomycin hydrolase H372A mutant 2022-04-01 2022-06-29 Zheng, Y.Z.,Cui, J.,Wang, Y.L.,Huang, S.J.,Lin, E.C.,Huang, S.C.,Rudolf, J.D.,Yan, X.,Chang, C.Y. The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease. Chembiochem 2022 23 0 0 7F7J The crystal structure of AKR4C17 2021-06-30 2022-07-06 Li, H.,Yang, Y.,Hu, Y.,Chen, C.C.,Huang, J.W.,Min, J.,Dai, L.,Guo, R.T. Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona J Hazard Mater 2022 436 129191 0 7F7K Crystal structure of AKR4C17 bound with NADP+ 2021-06-30 2022-07-06 Li, H.,Yang, Y.,Hu, Y.,Chen, C.C.,Huang, J.W.,Min, J.,Dai, L.,Guo, R.T. Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona J Hazard Mater 2022 436 129191 0 7F7L Crystal structure of AKR4C17 bound with NADPH 2021-06-30 2022-07-06 Li, H.,Yang, Y.,Hu, Y.,Chen, C.C.,Huang, J.W.,Min, J.,Dai, L.,Guo, R.T. Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona J Hazard Mater 2022 436 129191 0 7F7M AKR4C17 in complex with NADP+ and glyphosate 2021-06-30 2022-07-06 Li, H.,Yang, Y.,Hu, Y.,Chen, C.C.,Huang, J.W.,Min, J.,Dai, L.,Guo, R.T. Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona J Hazard Mater 2022 436 129191 0 7F8F Roadblock from Odinarchaeota LCB_4 2021-07-02 2022-07-13 Akil, C.,Robinson, R.C. Roadblock from Odinarchaeota LCB_4 To Be Published 0 0 0 0 7F8M Roadblock from Thorarchaeota SMTZ1-45 2021-07-02 2022-07-13 Tran, L.T.,Robinson, R.C. 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Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors. Commun Biol 2022 5 454 454 7FEW 37007650 Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues 2021-07-22 2022-07-27 Zhang, Y.,Chew, B.L.A.,Wang, J.,Yuan, M.,Yam, J.K.H.,Luo, D.,Yang, L. Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J 2023 21 2137 2146 7FF8 Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I) 2021-07-22 2022-07-27 Chew, B.L.A.,Luo, D.,Yang, L. Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr To Be Published 0 0 0 0 7EQM Apo Truncated VhChiP (Delta 1-19) 2021-05-04 2022-08-10 Aunkham, A.,Sanram, S.,Suginta, W. Structure and functionof truncated VhChiP To Be Published 0 0 0 0 7EQR Crystal structure of Truncated (Delta 1-19) Chitoporin VhChiP from Vibrio harveyi in complex with chitohexaose 2021-05-04 2022-08-10 Aunkham, A.,Sanram, S.,Suginta, S. Structure of truncated VhChiP complex with chitohexaose To Be Published 0 0 0 0 7VT8 35503211 Crystal structure of MtGlu5 from Meiothermus taiwanensis WR-220 2021-10-28 2022-09-07 Ye, T.J.,Huang, K.F.,Ko, T.P.,Wu, S.H. Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase. Acta Crystallogr D Struct Biol 2022 78 633 646 7VGL 36176888 Crystal structure of CmnC 2021-09-17 2022-09-21 Hsiao, Y.H.,Huang, S.J.,Lin, E.C.,Hsiao, P.Y.,Toh, S.I.,Chen, I.H.,Xu, Z.,Lin, Y.P.,Liu, H.J.,Chang, C.Y. Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer. 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Chitoporin from Serratia marcescens in-complex with chitohexaose To Be Published 0 0 0 0 7WG3 36288706 Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy 2021-12-28 2022-11-09 Lee, W.H.,Chen, X.,Liu, I.J.,Lee, J.H.,Hu, C.M.,Wu, H.C.,Wang, S.K.,Lee, W.H.,Ma, C. Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep 2022 41 111555 111555 7VZ6 35203422 The crystal structure of Non-hydrolyzing UDPGlcNAc 2-epimerase in complex with UDP-glucose 2021-11-15 2022-11-16 Rattinam, R.,Basha, R.S.,Wang, Y.L.,Wang, Z.C.,Hsu, N.S.,Lin, K.H.,Zadeh, S.M.,Adhikari, K.,Lin, J.P.,Li, T.L. KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity. Biomedicines 2022 10 0 0 7EXF 36762861 Crystal structure of wild-type from Arabidopsis thaliana complexed with Galactose 2021-05-27 2022-11-30 Chuankhayan, P.,Lee, R.H.,Guan, H.H.,Lin, C.C.,Chen, N.C.,Huang, Y.C.,Yoshimura, M.,Nakagawa, A.,Chen, C.J. Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product. Acta Crystallogr D Struct Biol 2023 79 154 167 7X97 35871296 Crystal structure of actinomycin D-echinomycin-d(AGCCCGT/ACGGGCT) complex 2022-03-15 2022-12-14 Satange, R.,Kao, S.H.,Chien, C.M.,Chou, S.H.,Lin, C.C.,Neidle, S.,Hou, M.H. Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism. Nucleic Acids Res. 2022 50 8867 8881 7UX5 36534810 Structure of PDL1 in complex with FP28136, a Helicon Polypeptide 2022-05-05 2022-12-28 Li, K.,Tokareva, O.S.,Thomson, T.M.,Wahl, S.C.T.,Travaline, T.L.,Ramirez, J.D.,Choudary, S.K.,Agarwal, S.,Walkup 4th, W.G.,Olsen, T.J.,Brennan, M.J.,Verdine, G.L.,McGee, J.H. De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA 2022 119 0 0 7UXQ 36534810 Structure of PDL1 in complex with FP28135, a Helicon Polypeptide 2022-05-05 2022-12-28 Li, K.,Tokareva, O.S.,Thomson, T.M.,Wahl, S.C.T.,Travaline, T.L.,Ramirez, J.D.,Choudary, S.K.,Agarwal, S.,Walkup 4th, W.G.,Olsen, T.J.,Brennan, M.J.,Verdine, G.L.,McGee, J.H. De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA 2022 119 0 0 7XCN 36646841 Crystal structure of the MttB-MttC complex at 2.7 A resolution 2022-03-24 2023-01-18 Li, J.,Kang, P.T.,Jiang, R.,Lee, J.Y.,Soares, J.A.,Krzycki, J.A.,Chan, M.K. Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex. Commun Biol 2023 6 54 54 7WQQ Retinoic acid receptor alpha mutant - N299H 2022-01-25 2023-01-25 Huang, X.X.,Ng, L.M.,Teh, B.T. Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling To Be Published 0 0 0 0 8HYG Crystal structure of protease-associated domain of Arabidopsis vacuolar sorting receptor 1 at pH 4.6 2023-01-06 2023-01-25 Tsao, H.E.,Lui, S.N.,Wong, K.B. Crystal structure of protease-associated domain of Arabidopsis vacuolar sorting receptor 1 at pH 4.6 To Be Published 0 0 0 0 7WUL Crystal structure of UBR bof from PRT6 (RDG pH5.5) 2022-02-08 2023-02-08 Ho, M.C.,Cao, J.J. Crystal structure of UBR box from PRT6 To Be Published 0 0 0 0 7WUM Crystal structure of UBR box from PRT6 (RDG pH 8.5) 2022-02-08 2023-02-08 Ho, M.C.,Cao, C.C. Crystal structure of UBR box from PRT6 To Be Published 0 0 0 0 8H9D 36917574 Crystal structure of Cas12a protein 2022-10-25 2023-02-08 Jianwei, L.,Jobichen, C.,Machida, S.,Meng, S.,Read, R.J.,Hongying, C.,Jian, S.,Yuan, Y.A.,Sivaraman, J. Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol. 2023 21 0 0 7XBS 36278314 Crystal structure of the adenylation domain of CmnG 2022-03-22 2023-03-01 Chen, I.H.,Cheng, T.,Wang, Y.L.,Huang, S.J.,Hsiao, Y.H.,Lai, Y.T.,Toh, S.I.,Chu, J.,Rudolf, J.D.,Chang, C.Y. Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis. Chembiochem 2022 23 0 0 7XBT 36278314 Crystal structure of the adenylation domain of CmnG in complex with AMP 2022-03-22 2023-03-01 Chen, I.H.,Cheng, T.,Wang, Y.L.,Huang, S.J.,Hsiao, Y.H.,Lai, Y.T.,Toh, S.I.,Chu, J.,Rudolf, J.D.,Chang, C.Y. Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis. Chembiochem 2022 23 0 0 7XBU 36278314 Crystal structure of the adenylation domain of CmnG in complex with capreomycidine 2022-03-22 2023-03-01 Chen, I.H.,Cheng, T.,Wang, Y.L.,Huang, S.J.,Hsiao, Y.H.,Lai, Y.T.,Toh, S.I.,Chu, J.,Rudolf, J.D.,Chang, C.Y. Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis. Chembiochem 2022 23 0 0 7XBV 36278314 Crystal structure of the adenylation domain of CmnG in complex with AMPCPP 2022-03-22 2023-03-01 Chen, I.H.,Cheng, T.,Wang, Y.L.,Huang, S.J.,Hsiao, Y.H.,Lai, Y.T.,Toh, S.I.,Chu, J.,Rudolf, J.D.,Chang, C.Y. Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis. Chembiochem 2022 23 0 0 7X3H The structure of Clostridium botulinum ParM in the apo conformation 2022-03-01 2023-03-08 Robinson, R.C.,Ali, S.,Narita, A. Structure of tubulin H393D mutant from Odinarchaeota To Be Published 0 0 0 0 7X4A 37604815 Native CD-NTase ClCdnE 2022-03-02 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X4C 37604815 Native CD-NTase EfCdnE 2022-03-02 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X4F 37604815 Native CD-NTase LpCdnE 2022-03-02 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X4G 37604815 CD-NTase ClCdnE in complex with substrate UTP 2022-03-02 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X4P 37604815 CD-NTase EfCdnE in complex with intermediate pppUpU 2022-03-03 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X4T 37604815 LpCdnE UMPNPP Mg complex 2022-03-03 2023-03-08 Yang, C.S.,Ko, T.P.,Chen, C.J.,Hou, M.H.,Wang, Y.C.,Chen, Y. Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun 2023 14 5078 5078 7X5P Truncated VhChiP (1-19aa) in complex with doxycycline 2022-03-05 2023-03-08 Aunkham, A.,Sanram, S.,Suginta, W. Structure and function of truncated VhChiP To Be Published 0 0 0 0 7X5Q Apo Truncated VhChiP (Delta 1-19) in complex with peptide (DGANSDAAK) 2022-03-05 2023-03-08 Aunkham, A.,Sanram, S.,Suginta, W.,Robinson, R.C. Structure and function of truncated VhChiP To Be Published 0 0 0 0 8IA4 Crystal structure of Cas2 in complex with AcrVA5-peptide 2023-02-07 2023-03-22 Mo, X. Insights into the inhibition of protospacer integration via interaction with Cas2 by an Anti-CRISPR protein To Be Published 0 0 0 0 7YQN 36997036 Crystal structure of Ecoli malate synthase G 2022-08-08 2023-03-29 Ho, M.R.,Wu, Y.M.,Lu, Y.C.,Ko, T.P.,Wu, K.P. Cryo-EM reveals the structure and dynamics of a 723-residue malate synthase G. J.Struct.Biol. 2023 215 107958 107958 7XGS Short vegetative phase protein 2022-04-06 2023-04-12 Pan, Z.-J.,Huang, Y.-C.,Cheng, H.-P.,Lin, C.-P.,Liao, Y.-T.,Ko, T.-P.,Wang, H.-C.,Lin, S.-S. The PHYL1 effector of peanut witches broom (PnWB) phytoplasma alters the miR156/157-mediated squamosa promoter binding protein like regulation and gibberellic acid generation to promote anthocyanin biosynthesis To Be Published 0 0 0 0 8HHG 37019934 The bacterial divisome protein complex FtsB-FtsL-FtsQ 2022-11-16 2023-04-26 Nguyen, H.T.V.,Chen, X.,Parada, C.,Luo, A.C.,Shih, O.,Jeng, U.S.,Huang, C.Y.,Shih, Y.L.,Ma, C. Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun 2023 14 1903 1903 8HHH 37019934 The bacterial divisome protein complex FtsB-FtsL-FtsQ 2022-11-16 2023-04-26 Nguyen, H.T.V.,Chen, X.,Parada, C.,Luo, A.C.,Shih, O.,Jeng, U.S.,Huang, C.Y.,Shih, Y.L.,Ma, C. Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun 2023 14 1903 1903 7WZZ 37296297 Crystal structure of peptide KAGQVVTIW in complex with HLA-B5801 2022-02-20 2023-05-03 Huan, X.,Zhuo, N.,Lee, H.Y.,Ren, E.C. Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep 2023 13 9373 9373 7X00 37296297 Crystal structure of peptide VSFIEFVGW in complex with HLA-B5801 2022-02-20 2023-05-03 Huan, X.,Zhuo, N.,Lee, H.Y.,Ren, E.C. Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep 2023 13 9373 9373 7X1B 37296297 Crystal structure of peptide KAGQVVTI in complex with HLA-B5801 2022-02-23 2023-05-03 Huan, X.,Zhuo, N.,Lee, H.Y.,Ren, E.C. Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep 2023 13 9373 9373 7X1C 37296297 Crystal structure of peptide VSFIEFVI in complex with HLA-B5801 2022-02-23 2023-05-03 Huan, X.,Zhuo, N.,Lee, H.Y.,Ren, E.C. Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep 2023 13 9373 9373 7XJW 35628479 Crystal structure of canine coronavirus main protease in complex with GC376 2022-04-18 2023-05-31 Ho, C.Y.,Yu, J.X.,Wang, Y.C.,Lin, Y.C.,Chiu, Y.F.,Gao, J.Y.,Lai, S.J.,Chen, M.J.,Huang, W.C.,Tien, N.,Chen, Y. A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism. Int J Mol Sci 2022 23 0 0 7XQA Orf1-glycine complex 2022-05-07 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry Nat Commun 2023 14 2528 0 7XXD 37137912 Orf1-sarcosine complex 2022-05-29 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 7XXM 37137912 Orf1-glycine-4-aminobutylthricin complex 2022-05-30 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 7XXP 37137912 F316A-glycine-streptothricin F complex 2022-05-30 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 7XYE 37137912 The apo structure of Orf1 2022-06-01 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 7XYL 37137912 E426Q-glycine-glycylthricin complex 2022-06-01 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 7Y2B 37245780 Crystal structure of CUG repeat RNA duplex containing U-U mismatches 2022-06-09 2023-05-31 Wang, S.C.,Chen, Y.T.,Satange, R.,Chu, J.W.,Hou, M.H. Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1. J.Biol.Chem. 2023 299 104864 104864 7YIA 36796558 Crystal structure of K74A mutant of Cap4 SAVED domain-containing receptor from Enterobacter cloacae 2022-07-15 2023-05-31 Chang, J.J.,You, B.J.,Tien, N.,Wang, Y.C.,Yang, C.S.,Hou, M.H.,Chen, Y. Specific recognition of cyclic oligonucleotides by Cap4 for phage infection. Int.J.Biol.Macromol. 2023 237 123656 123656 7YPU 37137912 OrfE-CoA-glycylthricin complex 2022-08-04 2023-05-31 Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L. N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun 2023 14 2528 2528 8GUL 37259836 Chitin-active AA10 LPMO (GbpA) complexed with Cu(II) from Vibrio campbellii 2022-09-12 2023-06-21 Zhou, Y.,Wannapaiboon, S.,Prongjit, M.,Pornsuwan, S.,Sucharitakul, J.,Kamonsutthipaijit, N.,Robinson, R.C.,Suginta, W. Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii. Acta Crystallogr D Struct Biol 2023 79 479 497 8GUM 37259836 Chitin-active AA10 LPMO (GbpA) from Vibrio campbellii 2022-09-12 2023-06-21 Zhou, Y.,Wannapaiboon, S.,Prongjit, M.,Pornsuwan, S.,Sucharitakul, J.,Kamonsutthipaijit, N.,Robinson, R.C.,Suginta, W. Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii. Acta Crystallogr D Struct Biol 2023 79 479 497 7YH1 Roadblock from Candidatus Prometheoarchaeum syntrophicum strain MK-D1 2022-07-12 2023-07-19 Robinson, R.C.,Tran, L.T. 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Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res. 2023 51 11927 11940 8JI2 37973794 Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan 2023-05-26 2023-11-15 Li, H.,Huang, J.W.,Dai, L.,Zheng, H.,Dai, S.,Zhang, Q.,Yao, L.,Yang, Y.,Yang, Y.,Min, J.,Guo, R.T.,Chen, C.C. The structural and functional investigation into an unusual nitrile synthase. Nat Commun 2023 14 7425 7425 8JI3 37973794 Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan and two Fe2+ 2023-05-26 2023-11-15 Li, H.,Huang, J.W.,Dai, L.,Zheng, H.,Dai, S.,Zhang, Q.,Yao, L.,Yang, Y.,Yang, Y.,Min, J.,Guo, R.T.,Chen, C.C. The structural and functional investigation into an unusual nitrile synthase. 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