PDB_ID PUBMED_CID STRUCTURE TITLE DEPOSITION DATE RELEASE DATE AUTHORS CITATION TITLE JOURNAL YEAR VOLUME FIRST PAGE LAST PAGE 1OUP 12881435 Crystal structure of the periplasmic endonuclease Vvn complexed with octamer double stranded DNA 2003-03-25 2003-08-05 Li, C.-L.,Hor, L.-I.,Chang, Z.-F.,Tsai, L.-C.,Yang, W.-Z.,Yuan, H.S. DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site. Embo J. 2003 22 4014 4025 1IZR 12962489 F46A mutant of bovine pancreatic ribonuclease A 2002-10-11 2003-11-25 Kadonosono, T.,Chatani, E.,Hayashi, R.,Moriyama, H.,Ueki, T. Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry 2003 42 10651 10658 1V4E 14617622 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima 2003-11-13 2004-03-02 Guo, R.T.,Kuo, C.J.,Chou, C.C.,Ko, T.P.,Shr, H.L.,Liang, P.H.,Wang, A.H.-J. Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem. 2004 279 4903 4912 1PT3 14962381 Crystal structures of nuclease-ColE7 complexed with octamer DNA 2003-06-22 2004-03-30 Hsia, K.C.,Chak, K.F.,Liang, P.H.,Cheng, Y.S.,Ku, W.Y.,Yuan, H.S. DNA binding and degradation by the HNH protein ColE7. STRUCTURE 2004 12 205 214 1WKQ 15180998 Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily 2004-06-01 2004-07-13 Liaw, S.H.,Chang, Y.J.,Lai, C.T.,Chang, H.C.,Chang, G.G. Crystal Structure of Bacillus subtilis Guanine Deaminase: THE FIRST DOMAIN-SWAPPED STRUCTURE IN THE CYTIDINE DEAMINASE SUPERFAMILY J.Biol.Chem. 2004 279 35479 35485 1PP6 15451675 VVA2 (STRIP CRYSTAL FORM) 2003-06-16 2004-08-24 Lin, S.-C.,Lo, Y.-C.,Lin, J.-Y.,Liaw, Y.-C. Crystal structures and electron micrographs of fungal volvatoxin A2 J.Mol.Biol. 2004 343 477 491 1R0M 15313614 Structure of Deinococcus radiodurans N-acylamino acid racemase at 1.3 : insights into a flexible binding pocket and evolution of enzymatic activity 2003-09-22 2004-09-22 Wang, W.-C.,Chiu, W.-C.,Hsu, S.-K.,Wu, C.-L.,Chen, C.-Y.,Liu, J.-S.,Hsu, W.-H. Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans J.Mol.Biol. 2004 342 155 169 1WP5 15466871 Crystal structure of the C-terminal domain of DNA topoisomerase IV 2004-08-30 2004-10-12 Hsieh, T.-J.,Farh, L.,Huang, W.M.,Chan, N.-L. Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis J.Biol.Chem. 2004 279 55587 55593 1XPY 15313614 Structural Basis for Catalytic Racemization and Substrate Specificity of an N-Acylamino Acid Racemase Homologue from Deinococcus radiodurans 2004-10-10 2004-10-26 Wang, W.-C.,Chiu, W.-C.,Hsu, S.-K.,Wu, C.-L.,Chen, C.-Y.,Liu, J.-S.,Hsu, W.-H. Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans J.Mol.Biol. 2004 342 155 169 1U24 15530366 Crystal structure of Selenomonas ruminantium phytase 2004-07-16 2004-11-09 Chu, H.M.,Guo, R.T.,Lin, T.W.,Chou, C.C.,Shr, H.L.,Lai, H.L.,Tang, T.Y.,Cheng, K.J.,Selinger, B.L.,Wang, A.H.-J. Structures of Selenomonas ruminantium Phytase in Complex with Persulfated Phytate; DSP Phytase Fold and Mechanism for Sequential Substrate Hydrolysis STRUCTURE 2004 12 2015 2024 1U25 15530366 Crystal structure of Selenomonas ruminantium phytase complexed with persulfated phytate in the C2221 crystal form 2004-07-16 2004-11-09 Chu, H.M.,Guo, R.T.,Lin, T.W.,Chou, C.C.,Shr, H.L.,Lai, H.L.,Tang, T.Y.,Cheng, K.J.,Selinger, B.L.,Wang, A.H.-J. Structures of Selenomonas ruminantium Phytase in Complex with Persulfated Phytate; DSP Phytase Fold and Mechanism for Sequential Substrate Hydrolysis STRUCTURE 2004 12 2015 2024 1PKU 15890279 Crystal Structure of Nucleoside Diphosphate Kinase from Rice 2003-06-06 2005-02-22 Huang, J.Y.,Chang, T.,Chang, C.Y.,Chen, C.J. Crystal structure of nucleoside diphosphate kinase required for coleoptile elongation in rice (Oryza sativa L.). J.Struct.Biol. 2005 150 309 318 1UG4 15895985 Crystal Structure of Cardiotoxin VI from Taiwan Cobra (Naja atra) Venom 2003-06-12 2005-02-22 Chen, T.S.,Chung, F.Y.,Tjong, S.C.,Goh, K.S.,Huang, W.N.,Chien, K.Y.,Wu, P.L.,Lin, H.C.,Chen, C.J.,Wu, W.G. Structural difference between group I and group II cobra cardiotoxins: X-ray, NMR, and CD analysis of the effect of cis-proline conformation on three-fingered toxins. Biochemistry 2005 44 7414 7426 1VBJ The crystal structure of prostaglandin F synthase from Trypanosoma brucei 2004-02-27 2005-04-12 Inoue, T. The crystal structure of prostaglandin F synthase from Trypanosoma brucei TO BE PUBLISHED 0 0 0 0 2AFO 16135565 Crystal structure of human glutaminyl cyclase at pH 8.0 2005-07-26 2005-08-23 Huang, K.F.,Liu, Y.L.,Cheng, W.J.,Ko, T.P.,Wang, A.H. Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa 2005 102 13117 13122 2AFS 16135565 Crystal structure of the genetic mutant R54W of human glutaminyl cyclase 2005-07-26 2005-08-23 Huang, K.F.,Liu, Y.L.,Cheng, W.J.,Ko, T.P.,Wang, A.H. Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa 2005 102 13117 13122 2A3R 16083857 Crystal Structure of Human Sulfotransferase SULT1A3 in Complex with Dopamine and 3-Phosphoadenosine 5-Phosphate 2005-06-26 2005-08-30 Lu, J.H.,Li, H.T.,Liu, M.C.,Zhang, J.P.,Li, M.,An, X.M.,Chang, W.R. Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate Biochem.Biophys.Res.Commun. 2005 335 417 423 1ZR6 16154992 The crystal structure of an Acremonium strictum glucooligosaccharide oxidase reveals a novel flavinylation 2005-05-19 2005-09-13 Huang, C.H.,Lai, W.L.,Lee, M.H.,Chen, C.J.,Vasella, A.,Tsai, Y.C.,Liaw, S.H. Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD J.Biol.Chem. 2005 280 38831 38838 2D27 16162504 Structure of the N-terminal domain of XpsE (crystal form I4122) 2005-09-03 2005-09-20 Chen, Y.,Shiue, S.-J.,Huang, C.-W.,Chang, J.-L.,Chien, Y.-L.,Hu, N.-T.,Chan, N.-L. Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System J.Biol.Chem. 2005 280 42356 42363 2D28 16162504 Structure of the N-terminal domain of XpsE (crystal form P43212) 2005-09-03 2005-09-20 Chen, Y.,Shiue, S.-J.,Huang, C.-W.,Chang, J.-L.,Chien, Y.-L.,Hu, N.-T.,Chan, N.-L. Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System J.Biol.Chem. 2005 280 42356 42363 2D5N Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis 2005-11-02 2005-11-29 Chen, S.J.,Chang, Y.C.,Liaw, S.H. Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis To be Published 0 0 0 0 1XTA Crystal Structure of Natrin, a snake venom CRISP from Taiwan cobra (Naja atra) 2004-10-21 2005-12-13 Wang, Y.-L.,Goh, K.-X.,Lee, S.-C.,Huang, W.-N.,Wu, W.-G.,Chen, C.-J. Structures of snake venom CRISP reveal an action mechanism involving serine protease and ion channel blocking domains To be Published 0 0 0 0 2AVF 16293231 Crystal Structure of C-terminal Desundecapeptide Nitrite Reductase from Achromobacter cycloclastes 2005-08-30 2005-12-20 Li, H.T.,Chang, T.,Chang, W.C.,Chen, C.J.,Liu, M.Y.,Gui, L.L.,Zhang, J.P.,An, X.M.,Chang, W.R. Crystal structure of C-terminal desundecapeptide nitrite reductase from Achromobacter cycloclastes Biochem.Biophys.Res.Commun. 2005 338 1935 1942 2CY1 17277442 Crystal structure of APE1850 2005-07-04 2006-01-04 Tanaka, H.,Umehara, T.,Inaka, K.,Takahashi, S.,Shibata, R.,Bessho, Y.,Sato, M.,Sugiyama, S.,Fusatomi, E.,Terada, T.,Shirouzu, M.,Sano, S.,Motohara, M.,Kobayashi, T.,Tanaka, T.,Tanaka, A.,Yokoyama, S. Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions Acta Crystallogr.,Sect.F 2007 63 69 73 1WS6 The Structure of Thermus thermphillus HB8 hypothetical protein TTHA0928 2004-11-01 2006-02-07 Sasaki, C.,Sugiura, I.,Sugio, S.,Tamura, T.,Inagaki, K. The structure of thermus thermphillus HB8 hypothetical protein TTHA0928 TO BE PUBLISHED 0 0 0 0 2F4B 16451087 Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist 2005-11-23 2006-02-14 Mahindroo, N.,Wang, C.C.,Liao, C.C.,Huang, C.F.,Lu, I.L.,Lien, T.W.,Peng, Y.H.,Huang, W.J.,Lin, Y.T.,Hsu, M.C.,Lin, C.H.,Tsai, C.H.,Hsu, J.T.,Chen, X.,Lyu, P.C.,Chao, Y.S.,Wu, S.Y.,Hsieh, H.P. Indol-1-yl Acetic Acids as Peroxisome Proliferator-Activated Receptor Agonists: Design, Synthesis, Structural Biology, and Molecular Docking Studies J.Med.Chem. 2006 49 1212 1216 1ZNV 16434744 How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor 2005-05-12 2006-03-14 Doudeva, L.G.,Huang, H.,Hsia, K.C.,Shi, Z.,Li, C.L.,Shen, Y.,Cheng, Y.S.,Yuan, H.S. Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci. 2006 15 269 280 2AZJ 16291686 Crystal structure for the mutant D81C of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase 2005-09-11 2006-03-14 Sun, H.Y.,Ko, T.P.,Kuo, C.J.,Guo, R.T.,Chou, C.C.,Liang, P.H.,Wang, A.H.J. Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures J.Bacteriol. 2005 187 8137 8148 2DH4 16554305 Geranylgeranyl pyrophosphate synthase 2006-03-22 2006-04-04 Chang, T.-H.,Guo, R.-T.,Ko, T.-P.,Wang, A.H.,Liang, P.-H. Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination. J.Biol.Chem. 2006 281 14991 15000 2GGG 16650857 The mutant A68C-D72C of Deinococcus Radiodurans N-acylamino acid racemase 2006-03-24 2006-04-11 Chiu, W.C.,You, J.Y.,Liu, J.S.,Hsu, S.K.,Hsu, W.H.,Shih, C.H.,Hwang, J.K.,Wang, W.C. Structure-Stability-Activity Relationship in Covalently Cross-linked N-Carbamoyl d-Amino acid Amidohydrolase and N-Acylamino acid Racemase. J.Mol.Biol. 2006 359 741 753 1ZOI 16321951 Crystal Structure of a Stereoselective Esterase from Pseudomonas putida IFO12996 2005-05-13 2006-05-02 Elmi, F.,Lee, H.T.,Huang, J.Y.,Hsieh, Y.C.,Wang, Y.L.,Chen, Y.J.,Shaw, S.Y.,Chen, C.J. Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis J.Bacteriol. 2005 187 8470 8476 2G0H 16640330 Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities 2006-02-13 2006-05-16 Lu, I.L.,Huang, C.F.,Peng, Y.H.,Lin, Y.T.,Hsieh, H.P.,Chen, C.T.,Lien, T.W.,Lee, H.J.,Mahindroo, N.,Prakash, E.,Yueh, A.,Chen, H.Y.,Goparaju, C.M.,Chen, X.,Liao, C.C.,Chao, Y.S.,Hsu, J.T.,Wu, S.Y. 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Crystal structure of a putative acyl-CoA thioesterase from Xanthomonas campestris (XC229) adopts a tetrameric hotdog fold of epsilongamma mode. Proteins 2006 64 823 826 2FUK 16754966 Crystal structure of XC6422 from Xanthomonas campestris: a member of a/b serine hydrolase without lid at 1.6 resolution 2006-01-27 2006-07-04 Yang, C.Y.,Chin, K.H.,Chou, C.C.,Wang, A.H.J.,Chou, S.H. Structure of XC6422 from Xanthomonas campestris at 1.6 A resolution: a small serine alpha/beta-hydrolase Acta Crystallogr.,Sect.F 2006 62 498 503 2GZ7 16913704 Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease 2006-05-11 2006-08-29 Lu, I.L.,Mahindroo, N.,Liang, P.H.,Peng, Y.H.,Kuo, C.J.,Tsai, K.C.,Hsieh, H.P.,Chao, Y.S.,Wu, S.Y. Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease J.Med.Chem. 2006 49 5154 5161 2GZ8 16913704 Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease 2006-05-11 2006-08-29 Lu, I.L.,Mahindroo, N.,Liang, P.H.,Peng, Y.H.,Kuo, C.J.,Tsai, K.C.,Hsieh, H.P.,Chao, Y.S.,Wu, S.Y. Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease J.Med.Chem. 2006 49 5154 5161 2DUU 16880542 Crystal Structure of apo-form of NADP-Dependent Glyceraldehyde-3-Phosphate Dehydrogenase from Synechococcus Sp. 2006-07-27 2006-09-05 Kitatani, T.,Nakamura, Y.,Wada, K.,Kinoshita, T.,Tamoi, M.,Shigeoka, S.,Tada, T. Structure of apo-glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942 Acta Crystallogr.,Sect.F 2006 62 727 730 2GSC 16948161 Crystal Structure of the Conserved Hypothetical Cytosolic Protein Xcc0516 from Xanthomonas campestris 2006-04-26 2006-10-03 Lin, L.Y.,Ching, C.L.,Chin, K.H.,Chou, S.H.,Chan, N.L. Crystal structure of the conserved hypothetical cytosolic protein Xcc0516 from Xanthomonas campestris reveals a novel quaternary structure assembled by five four-helix bundles. Proteins 2006 65 783 786 2DSX 16930541 Crystal structure of rubredoxin from Desulfovibrio gigas to ultra-high 0.68 A resolution 2006-07-07 2006-10-10 Chen, C.J.,Lin, Y.H.,Huang, Y.C.,Liu, M.Y. Crystal structure of rubredoxin from Desulfovibrio gigas to ultra-high 0.68A resolution Biochem.Biophys.Res.Commun. 2006 349 79 90 2IAG 17020766 Crystal structure of human prostacyclin synthase 2006-09-08 2006-10-10 Chiang, C.-W.,Yeh, H.-C.,Wang, L.-H.,Chan, N.-L. 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The crystal structure of XC1739: a putative multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris at 1.8 A resolution Proteins 2006 65 239 242 2IOB 17124497 E. coli Bifunctional glutathionylspermidine synthetase/amidase Apo protein 2006-10-10 2006-12-12 Pai, C.H.,Chiang, B.Y.,Ko, T.P.,Chou, C.C.,Chong, C.M.,Yen, F.J.,Chen, S.,Coward, J.K.,Wang, A.H.-J.,Lin, C.H. Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase Embo J. 2006 25 5970 5982 2IOB 17124497 E. coli Bifunctional glutathionylspermidine synthetase/amidase Apo protein 2006-10-10 2006-12-12 Pai, C.H.,Chiang, B.Y.,Ko, T.P.,Chou, C.C.,Chong, C.M.,Yen, F.J.,Chen, S.,Coward, J.K.,Wang, A.H.-J.,Lin, C.H. 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Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem. 2008 51 5594 5607 2Z50 18800762 S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-28 2007-06-26 2008-07-01 Chen, C.K.-M.,Hudock, M.P.,Zhang, Y.,Guo, R.-T.,Cao, R.,No, J.H.,Liang, P.-H.,Ko, T.-P.,Chang, T.-H.,Chang, S.-C.,Song, Y.,Axelson, J.,Kumar, A.,Wang, A.H.-J.,Oldfield, E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem. 2008 51 5594 5607 2Z52 18800762 S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-23 2007-06-26 2008-07-01 Chen, C.K.-M.,Hudock, M.P.,Zhang, Y.,Guo, R.-T.,Cao, R.,No, J.H.,Liang, P.-H.,Ko, T.-P.,Chang, T.-H.,Chang, S.-C.,Song, Y.,Axelson, J.,Kumar, A.,Wang, A.H.-J.,Oldfield, E. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem. 2008 51 5594 5607 2QN5 Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin 2007-07-18 2008-07-22 Li, H.T.,Lin, Y.H.,Huang, Y.C.,Guan, H.H.,Hsieh, Y.C.,Chang, T.,Wang, A.H.J.,Chen, C.J. Crystal Structure and Functional Study of the Bowman-Birk Inhibitor from Rice Bran in Complex with Bovine Trypsin To be Published 0 0 0 0 2ZE3 18433062 Crystal Structure of DFA0005 Complexed with alpha-Ketoglutarate: A Novel Member of the ICL/PEPM Superfamily from Alkali-tolerant Deinococcus ficus 2007-12-05 2008-08-12 Liao, C.J.,Chin, K.H.,Lin, C.H.,Tsai, P.S.,Lyu, P.C.,Young, C.C.,Wang, A.H.,Chou, S.H. Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus Proteins 2008 73 362 371 3BDL 18453631 Crystal structure of a truncated human Tudor-SN 2007-11-15 2008-08-26 Li, C.L.,Yang, W.Z.,Chen, Y.P.,Yuan, H.S. Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing. Nucleic Acids Res. 2008 36 3579 3589 2ZB3 19000823 Crystal structure of mouse 15-ketoprostaglandin delta-13-reductase in complex with NADPH 2007-10-16 2008-09-30 Wu, Y.H.,Ko, T.P.,Guo, R.T.,Hu, S.M.,Chuang, L.M.,Wang, A.H.J. Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure 2008 16 1714 1723 3C12 18599076 Crystal Structure of FlgD from Xanthomonas campestris: Insights into the Hook Capping Essential for Flagellar Assembly 2008-01-22 2008-12-09 Kuo, W.-T.,Chin, K.-H.,Lo, W.-T.,Wang, A.H.-J.,Chou, S.-H. 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Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity Plos One 2009 4 0 0 3GWJ 19358695 Crystal structure of Antheraea pernyi arylphorin 2009-04-01 2009-05-05 Ryu, K.S.,Lee, J.O.,Kwon, T.H.,Choi, H.H.,Park, H.S.,Hwang, S.K.,Lee, Z.W.,Lee, K.B.,Han, Y.H.,Choi, Y.S.,Jeon, Y.H.,Cheong, C.,Kim, S. The presence of monoglucosylated N196-glycan is important for the structural stability of storage protein, arylphorin Biochem.J. 2009 421 87 96 2VW9 19285993 Single stranded DNA binding protein complex from Helicobacter pylori 2008-06-18 2009-06-02 Chan, K.-W.,Lee, Y.-J.,Wang, C.-H.,Huang, H.,Sun, Y.-J. Single-Stranded DNA-Binding Protein Complex from Helicobacter Pylori Suggests an Ssdna-Binding Surface. J.Mol.Biol. 2009 388 508 0 2ZYH 19447113 mutant A. 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Insights into the alkyl peroxide reduction pathway of Xanthomonas campestris bacterioferritin comigratory protein from the trapped intermediate-ligand complex structures J.Mol.Biol. 2009 390 951 966 3GD0 19640850 Crystal structure of laminaripentaose-producing beta-1,3-glucanase 2009-02-23 2009-07-28 Wu, H.M.,Liu, S.W.,Hsu, M.T.,Hung, C.L.,Lai, C.C.,Cheng, W.C.,Wang, H.J.,Li, Y.K.,Wang, W.C. Structure, mechanistic action, and essential residues of a GH-64 enzyme, laminaripentaose-producing beta-1,3-glucanase. J.Biol.Chem. 2009 284 26708 26715 3E5R Crystal structure and Functional Analysis of Glyceraldehyde-3-phosphate Dehydrogenase from Oryza Sativa 2008-08-14 2009-08-18 Tien, Y.C.,Lin, Y.H.,Chang, S.L.,Chen, C.J. 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J.Biol.Chem. 2010 285 3245 0 3K7D 20026075 C-terminal (adenylylation) domain of E.coli Glutamine Synthetase Adenylyltransferase 2009-10-12 2009-12-15 Xu, Y.,Carr, P.D.,Vasudevan, S.G.,Ollis, D.L. Structure of the Adenylylation Domain of E. coli Glutamine Synthetase Adenylyl Transferase: Evidence for Gene Duplication and Evolution of a New Active Site. J.Mol.Biol. 2010 396 773 784 3I4L 19944110 Structural characterization for the nucleotide binding ability of subunit A with AMP-PNP of the A1AO ATP synthase 2009-07-01 2010-01-12 Kumar, A.,Manimekalai, M.S.,Balakrishna, A.M.,Jeyakanthan, J.,Gruber, G. Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution. J.Mol.Biol. 2010 396 301 320 3A7G 20124694 Human MST3 kinase 2009-09-26 2010-02-02 Ko, T.P.,Jeng, W.Y.,Liu, C.I.,Lai, M.D.,Wu, C.L.,Chang, W.J.,Shr, H.L.,Lu, T.J.,Wang, A.H.J. Structures of human MST3 kinase in complex with adenine, ADP and Mn2+. 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Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell 2010 22 454 467 3K7L 19932752 Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins 2009-10-13 2010-03-02 Guan, H.H.,Goh, K.S.,Davamani, F.,Wu, P.L.,Huang, Y.W.,Jeyakanthan, J.,Wu, W.G.,Chen, C.J. Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins J.Struct.Biol. 2010 169 294 303 3K7N 19932752 Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins 2009-10-13 2010-03-02 Guan, H.H.,Goh, K.S.,Davamani, F.,Wu, P.L.,Huang, Y.W.,Jeyakanthan, J.,Wu, W.G.,Chen, C.J. 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Crystal structure of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete sbusites in the active site for catalysis To be Published 0 0 0 0 3LDR Crystal structure of fructosyltransferase (D191A) from A. japonicus in complex with 1-Kestose 2010-01-13 2010-05-12 Chuankhayan, P.,Hsieh, C.Y.,Huang, Y.C.,Hsieh, Y.Y.,Guan, H.H.,Hsieh, Y.C.,Tien, Y.C.,Chen, C.D.,Chaing, C.M.,Chen, C.J. Crystal structure of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete sbusites in the active site for catalysis To be Published 0 0 0 0 3LEM Crystal structure of fructosyltransferase (D191A) from A. japonicus in complex with Nystose 2010-01-15 2010-05-12 Chuankhayan, P.,Hsieh, C.Y.,Huang, Y.C.,Hsieh, Y.Y.,Guan, H.H.,Hsieh, Y.C.,Tien, Y.C.,Chen, C.D.,Chaing, C.M.,Chen, C.J. Crystal structure of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete sbusites in the active site for catalysis To be Published 0 0 0 0 3LFI Crystal structure of fructosyltransferase (wild-type) from A. japonicus in complex with glucose 2010-01-17 2010-05-12 Chuankhayan, P.,Hsieh, C.Y.,Huang, Y.C.,Hsieh, Y.Y.,Guan, H.H.,Hsieh, Y.C.,Tien, Y.C.,Chen, C.D.,Chaing, C.M.,Chen, C.J. Crystal structure of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete sbusites in the active site for catalysis To be Published 0 0 0 0 3LIH 20466731 Crystal structure of fructosyltransferase (D191A) from A. japonicus in complex with raffinose 2010-01-24 2010-05-12 Chuankhayan, P.,Hsieh, C.Y.,Huang, Y.C.,Hsieh, Y.Y.,Guan, H.H.,Hsieh, Y.C.,Tien, Y.C.,Chen, C.D.,Chiang, C.M.,Chen, C.J. Crystal structures of Aspergillus japonicus fructosyltransferase complex with donor/acceptor substrates reveal complete subsites in the active site for catalysis J.Biol.Chem. 2010 285 23251 23264 3LG8 20571891 Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase 2010-01-19 2010-07-07 Balakrishna, A.M.,Manimekalai, M.S.S.,Hunke, C.,Gayen, S.,Rossle, M.,Jeyakanthan, J.,Gruber, G. Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering J.Bioenerg.Biomembr. 2010 42 311 320 3N12 20685646 Crystal stricture of chitinase in complex with zinc atoms from Bacillus cereus NCTU2 2010-05-15 2010-08-04 Hsieh, Y.-C.,Wu, Y.-J.,Chiang, T.-Y.,Kuo, C.-Y.,Shrestha, K.L.,Chao, C.-F.,Huang, Y.-C.,Chuankhayan, P.,Wu, W.-G.,Li, Y.-K.,Chen, C.-J. Crystal structures of bacillus cereus NCTU2 chitinase complexes with chitooligomers reveal novel substrate binding for catalysis: a chitinase without chitin-binding and insertion domains J.Biol.Chem. 2010 285 31603 31615 3N12 20685646 Crystal stricture of chitinase in complex with zinc atoms from Bacillus cereus NCTU2 2010-05-15 2010-08-04 Hsieh, Y.-C.,Wu, Y.-J.,Chiang, T.-Y.,Kuo, C.-Y.,Shrestha, K.L.,Chao, C.-F.,Huang, Y.-C.,Chuankhayan, P.,Wu, W.-G.,Li, Y.-K.,Chen, C.-J. Crystal structures of bacillus cereus NCTU2 chitinase complexes with chitooligomers reveal novel substrate binding for catalysis: a chitinase without chitin-binding and insertion domains J.Biol.Chem. 2010 285 31603 31615 3MRU 20819954 Crystal Structure of Aminoacylhistidine Dipeptidase from Vibrio alginolyticus 2010-04-29 2010-09-01 Chang, C.-Y.,Hsieh, Y.-C.,Wang, T.-Y.,Chen, Y.-C.,Wang, Y.-K.,Chiang, T.-W.,Chen, Y.-J.,Chang, C.-H.,Chen, C.-J.,Wu, T.-K. Crystal structure and mutational analysis of aminoacylhistidine dipeptidase from vibrio alginolyticus reveal a new architecture of M20 metallopeptidases J.Biol.Chem. 2010 285 39500 39510 3APZ 21220764 Apo form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase 2010-10-24 2011-01-19 Hsieh, F.-L.,Chang, T.-H.,Ko, T.-P.,Wang, A.H.-J. Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase Plant Physiol. 2011 155 1079 1090 3LBC D-sialic acid aldolase complexed with L-arabinose 2010-01-08 2011-01-19 Chou, C.-Y.,Ko, T.-P.,Wu, K.-J.,Huang, K.-F.,Lin, C.-H.,Wong, C.-H.,Wang, A.H.-J. Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251 To be Published 0 0 0 0 3LCW L-KDO aldolase complexed with hydroxypyruvate 2010-01-12 2011-01-19 Chou, C.-Y.,Ko, T.-P.,Wu, K.-J.,Huang, K.-F.,Lin, C.-H.,Wong, C.-H.,Wang, A.H.-J. Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251 To be Published 0 0 0 0 3P20 21396943 Crystal structure of vanadate bound subunit A of the A1AO ATP synthase 2010-10-01 2011-03-30 Manimekalai, M.S.,Kumar, A.,Jeyakanthan, J.,Gruber, G. The transition-like state and Pi entrance into the catalytic a subunit of the biological engine A-ATP synthase. J.Mol.Biol. 2011 408 736 754 3MRS 22438938 Crystal structure of shikimate kinase mutant (R57A) from Helicobacter pylori 2010-04-29 2011-05-04 Cheng, W.C.,Chen, Y.F.,Wang, H.J.,Hsu, K.C.,Lin, S.C.,Chen, T.J.,Yang, J.M.,Wang, W.C. Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism Plos One 2012 7 0 0 3N2E 22438938 Crystal structure of Helicobactor pylori shikimate kinase in complex with NSC162535 2010-05-18 2011-05-18 Cheng, W.C.,Chen, Y.F.,Wang, H.J.,Hsu, K.C.,Lin, S.C.,Chen, T.J.,Yang, J.M.,Wang, W.C. Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism Plos One 2012 7 0 0 3QX3 21778401 Human topoisomerase IIbeta in complex with DNA and etoposide 2011-03-01 2011-07-06 Wu, C.C.,Li, T.K.,Farh, L.,Lin, L.Y.,Lin, T.S.,Yu, Y.J.,Yen, T.J.,Chiang, C.W.,Chan, N.L. Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide Science 2011 333 459 462 3RO0 21875148 Crystal structure of Bacillus amyloliquefaciens pyroglutamyl peptidase I and terpyridine platinum(II) 2011-04-25 2011-10-05 Lo, Y.-C.,Su, W.-C.,Ko, T.-P.,Wang, N.-C.,Wang, A.H.-J. Terpyridine platinum(II) complexes inhibit cysteine proteases by binding to active-site cysteine. J.Biomol.Struct.Dyn. 2011 29 267 282 3PHG Crystal structure of the Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori 2010-11-04 2011-11-09 Cheng, W.C.,Lin, S.C.,Wang, W.C. Crystal structure of the Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori To be Published 0 0 0 0 3VA1 22211259 Crystal structure of the mammalian MDC1 FHA domain 2011-12-28 2012-02-01 Wu, H.H.,Wu, P.Y.,Huang, K.F.,Kao, Y.Y.,Tsai, M.D. Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry 2012 0 0 0 3VIK 22751668 Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with cellobiose 2011-10-03 2012-07-04 Jeng, W.Y.,Wang, N.C.,Lin, C.T.,Chang, W.J.,Liu, C.I.,Wang, A.H.J. High-resolution structures of Neotermes koshunensis beta-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates Acta Crystallogr.,Sect.D 2012 68 829 838 3VIN 22751668 Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with a new glucopyranosidic product 2011-10-03 2012-07-04 Jeng, W.Y.,Wang, N.C.,Lin, C.T.,Chang, W.J.,Liu, C.I.,Wang, A.H.J. High-resolution structures of Neotermes koshunensis beta-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates Acta Crystallogr.,Sect.D 2012 68 829 838 3SSA Crystal structure of subunit B mutant N157T of the A1AO ATP synthase 2011-07-08 2012-09-05 Sundararaman, L.,Manimekalai, M.S.S.,Gruber, G. Structure of subunit A mutants H156A, N157A and N157T of the A1AO ATP synthase To be Published 0 0 0 0 3TGW Crystal structure of subunit B mutant H156A of the A1AO ATP synthase 2011-08-18 2012-09-05 Tadwal, V.S.,Manimekalai, M.S.S.,Gruber, G. Structure of subunit A mutants H156A, N157A and N157T of the A1AO ATP synthase To be Published 0 0 0 0 3TIV Crystal structure of subunit B mutant N157A of the A1AO ATP synthase 2011-08-22 2012-09-05 Tadwal, V.S.,Manimekalai, M.S.S.,Gruber, G. Structure of subunit A mutants H156A, N157A and N157T of the A1AO ATP synthase To be Published 0 0 0 0 3VOP 23990784 Structure of Vaccinia virus A27 2012-01-31 2013-03-06 Chang, T.H.,Chang, S.J.,Hsieh, F.L.,Ko, T.P.,Lin, C.T.,Ho, M.R.,Wang, I.,Hsu, S.T.,Guo, R.T.,Chang, W.,Wang, A.H. Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein. Plos Pathog. 2013 9 0 0 4FS9 23118975 Complex structure of a broad specificity amino acid racemase (Bar) within the reactive intermediate 2012-06-27 2013-03-06 Wu, H.M.,Kuan, Y.C.,Chu, C.H.,Hsu, W.H.,Wang, W.C. Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants Plos One 2012 7 0 0 4EM0 staphylococcus aureus MarR in complex with salicylate and kanamycin 2012-04-11 2013-04-17 Chang, Y.M.,Chen, C.K.-M.,Wang, A.H.-J. Staphylococcus aureus MarR complexes To be Published 0 0 0 0 4EM2 seleno-methionine staphylococcus aureus MarR in complex with salicylate 2012-04-11 2013-04-17 Chang, Y.M.,Ko, T.-P.,Chen, C.K.-M.,Wang, A.H.-J. Staphylococcus aureus MarR complexes To be Published 0 0 0 0 4JBP 23610398 Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules 2013-02-20 2013-06-05 Wu, J.M.,Chen, C.T.,Coumar, M.S.,Lin, W.H.,Chen, Z.J.,Hsu, J.T.,Peng, Y.H.,Shiao, H.Y.,Lin, W.H.,Chu, C.Y.,Wu, J.S.,Lin, C.T.,Chen, C.P.,Hsueh, C.C.,Chang, K.Y.,Kao, L.P.,Huang, C.Y.,Chao, Y.S.,Wu, S.Y.,Hsieh, H.P.,Chi, Y.H. Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc.Natl.Acad.Sci.USA 2013 110 0 0 4JQ7 23611691 Crystal structure of EGFR kinase domain in complex with compound 2a 2013-03-20 2013-06-19 Peng, Y.H.,Shiao, H.Y.,Tu, C.H.,Liu, P.M.,Hsu, J.T.,Amancha, P.K.,Wu, J.S.,Coumar, M.S.,Chen, C.H.,Wang, S.Y.,Lin, W.H.,Sun, H.Y.,Chao, Y.S.,Lyu, P.C.,Hsieh, H.P.,Wu, S.Y. Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors J.Med.Chem. 2013 56 3889 3903 4JQ8 23611691 Crystal structure of EGFR kinase domain in complex with compound 4b 2013-03-20 2013-06-19 Peng, Y.H.,Shiao, H.Y.,Tu, C.H.,Liu, P.M.,Hsu, J.T.,Amancha, P.K.,Wu, J.S.,Coumar, M.S.,Chen, C.H.,Wang, S.Y.,Lin, W.H.,Sun, H.Y.,Chao, Y.S.,Lyu, P.C.,Hsieh, H.P.,Wu, S.Y. Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors J.Med.Chem. 2013 56 3889 3903 4JR3 23611691 Crystal structure of EGFR kinase domain in complex with compound 3g 2013-03-21 2013-06-19 Peng, Y.H.,Shiao, H.Y.,Tu, C.H.,Liu, P.M.,Hsu, J.T.,Amancha, P.K.,Wu, J.S.,Coumar, M.S.,Chen, C.H.,Wang, S.Y.,Lin, W.H.,Sun, H.Y.,Chao, Y.S.,Lyu, P.C.,Hsieh, H.P.,Wu, S.Y. Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors J.Med.Chem. 2013 56 3889 3903 4JRV 23611691 Crystal structure of EGFR kinase domain in complex with compound 4c 2013-03-22 2013-06-19 Peng, Y.H.,Shiao, H.Y.,Tu, C.H.,Liu, P.M.,Hsu, J.T.,Amancha, P.K.,Wu, J.S.,Coumar, M.S.,Chen, C.H.,Wang, S.Y.,Lin, W.H.,Sun, H.Y.,Chao, Y.S.,Lyu, P.C.,Hsieh, H.P.,Wu, S.Y. Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors J.Med.Chem. 2013 56 3889 3903 4GZ7 The crystal structure of Apo-dihydropyrimidinase from Tetraodon nigroviridis 2012-09-06 2013-09-11 Hsien, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Lysine Carboxylation: Metal and Structure Requirements for Post-translational Modification To be Published 0 0 0 0 4H00 The crystal structure of mon-Zn dihydropyrimidinase from Tetraodon nigroviridis 2012-09-06 2013-09-11 Hsieh, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification To be Published 0 0 0 0 4H01 The crystal structure of di-Zn dihydropyrimidinase from Tetraodon nigroviridis 2012-09-06 2013-09-11 Hsieh, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification To be Published 0 0 0 0 4LCQ 24005677 The crystal structure of di-Zn dihydropyrimidinase in complex with NCBI 2013-06-22 2013-09-18 Hsieh, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem. 2013 288 30645 30658 4LCR 24005677 The crystal structure of di-Zn dihydropyrimidinase in complex with NCBA 2013-06-22 2013-09-18 Hsieh, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem. 2013 288 30645 30658 4LCS 24005677 The crystal structure of di-Zn dihydropyrimidinase in complex with hydantoin 2013-06-23 2013-09-18 Hsieh, Y.C.,Chen, M.C.,Hsu, C.C.,Chan, S.I.,Yang, Y.S.,Chen, C.J. Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem. 2013 288 30645 30658 4HLL Crystal structure of Artificial ankyrin repeat protein_Ank(GAG)1D4 2012-10-17 2013-10-23 Chuankhayan, P.,Nangola, S.,Minard, P.,Boulanger, P.,Hong, S.S.,Tayapiwatana, C.,Chen, C.-J. Identification of Gag bioactive determinants specific to designed ankyrin and interfering in HIV-1 assembly To be Published 0 0 0 0 4HLL Crystal structure of Artificial ankyrin repeat protein_Ank(GAG)1D4 2012-10-17 2013-10-23 Chuankhayan, P.,Nangola, S.,Minard, P.,Boulanger, P.,Hong, S.S.,Tayapiwatana, C.,Chen, C.-J. Identification of Gag bioactive determinants specific to designed ankyrin and interfering in HIV-1 assembly To be Published 0 0 0 0 4BE6 24340031 V. cholera biofilm scaffolding protein RbmA 2013-03-06 2013-12-18 Maestre-Reyna, M.,Wu, W.-J.,Wang, A.H.-J. Structural Insights Into Rbma, a Biofilm Scaffolding Protein of V. Cholerae. Plos One 2013 8 82458 0 4L7Q 24028568 Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish 2013-06-14 2014-05-14 Chuankhayan, P.,Kao, T.-T.,Lin, C.-C.,Guan, H.-H.,Nakagawa, A.,Fu, T.-F.,Chen, C.-J. Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem. 2013 56 7625 7635 4M2G 24505011 Crystal structure of non-heme iron oxygenase OrfP in complex with Fe, succinate, and (3R,4R)-dihydroxy-L-Arg 2013-08-05 2014-06-25 Chang, C.Y.,Lyu, S.Y.,Liu, Y.C.,Hsu, N.S.,Wu, C.C.,Tang, C.F.,Lin, K.H.,Ho, J.Y.,Wu, C.J.,Tsai, M.D.,Li, T.L. Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl. 2014 53 1943 1948 4M2I 24505011 Crystal structure of non-heme iron oxygenase OrfP in complex with Fe 2013-08-05 2014-06-25 Chang, C.Y.,Lyu, S.Y.,Liu, Y.C.,Hsu, N.S.,Wu, C.C.,Tang, C.F.,Lin, K.H.,Ho, J.Y.,Wu, C.J.,Tsai, M.D.,Li, T.L. Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl. 2014 53 1943 1948 4LXL Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3 2013-07-30 2014-07-30 Wang, W.-C.,Chu, C.-H.,Chen, C.-C. Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3 To be Published 0 0 0 0 4QPD 25849409 Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with tetrahydrofolate 2014-06-23 2015-04-15 Lin, C.C.,Chuankhayan, P.,Chang, W.N.,Kao, T.T.,Guan, H.H.,Fun, H.K.,Nakagawa, A.,Fu, T.F.,Chen, C.J. Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D 2015 71 1006 1021 4TS4 25849409 Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) from zebrafish 2014-06-18 2015-04-15 Lin, C.C.,Chuankhayan, P.,Chang, W.N.,Kao, T.T.,Guan, H.H.,Fun, H.K.,Nakagawa, A.,Fu, T.F.,Chen, C.J. Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D 2015 71 1006 1021 4QQR Structural insight into nucleotide rhamnose synthase/epimerase-reductase from Arabidopsis thaliana 2014-06-28 2015-07-01 Han, X.,Liu, X. Structural insight into nucleotide rhamnose synthase/epimerase-reductase from Arabidopsis thaliana To be Published 0 0 0 0 4UA2 26150423 Crystal structure of dual function transcriptional regulator MerR from Bacillus megaterium MB1 2014-08-07 2015-07-22 Chang, C.C.,Lin, L.Y.,Zou, X.W.,Huang, C.C.,Chan, N.L. Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res. 2015 43 7612 7623 4XZW Endo-glucanase chimera C10 2015-02-05 2016-02-10 Wang, A.H.J.,Lee, C.C.,Chang, C.J.,Ho, T.H.D.,Chao, Y.C. Endo-glucanase chimera C10 To Be Published 0 0 0 0 5F8S 27010847 Crystal structure of a Crenomytilus grayanus lectin 2015-12-09 2016-04-06 Liao, J.-H.,Chien, C.-T.,Wu, H.-Y.,Huang, K.-F.,Wang, I.,Ho, M.-R.,Tu, I.-F.,Lee, I.-M.,Li, W.,Shih, Y.-L.,Wu, C.-Y.,Lukyanov, P.A.,Hsu, S.D.,Wu, S.-H. A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3 J.Am.Chem.Soc. 2016 138 4787 4795 4YS2 RCK domain with CDA 2015-03-16 2016-04-27 Chin, K.H.,Chou, S.H. RCK domain with CDA To Be Published 0 0 0 0 5IUI 27031565 Crystal Structure of Anaplastic Lyphoma Kinase (ALK) in complex with 4 2016-03-18 2016-05-18 Tu, C.H.,Lin, W.H.,Peng, Y.H.,Hsu, T.,Wu, J.S.,Chang, C.Y.,Lu, C.T.,Lyu, P.C.,Shih, C.,Jiaang, W.T.,Wu, S.Y. Pyrazolylamine Derivatives Reveal the Conformational Switching between Type I and Type II Binding Modes of Anaplastic Lymphoma Kinase (ALK). J.Med.Chem. 2016 59 3906 3919 5F29 26171638 Structure of RCK domain with cda 2015-12-01 2017-02-01 Chin, K.H.,Liang, J.M.,Yang, J.G.,Shih, M.S.,Tu, Z.L.,Wang, Y.C.,Sun, X.H.,Hu, N.J.,Liang, Z.X.,Dow, J.M.,Ryan, R.P.,Chou, S.H. Structural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK. Biochemistry 2015 54 4936 4951 5HXO 30023621 Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase with D71M, E75A and H103Y Mutants 2016-01-31 2017-04-05 Chan, Y.T.,Ko, T.P.,Yao, S.H.,Chen, Y.W.,Lee, C.C.,Wang, A.H. Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase. Acs Omega 2017 2 930 936 5GY0 30609216 Crystal structure of endoglucanase CelQ from Clostridium thermocellum complexed with cellotetraose 2016-09-21 2017-09-27 Jeng, W.Y.,Liu, C.I.,Lu, T.J.,Lin, H.J.,Wang, N.C.,Wang, A.H. Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris. Chembiochem 2019 20 295 307 6F02 Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution 2017-11-17 2018-12-12 Zhou, A.,Ma, L. Crystal structure of human Kallistatin To Be Published 0 0 0 0 6F2Z Structure of a Fc mutant 2017-11-27 2018-12-12 Zhou, A.,Li, S. Structure of Fc mutant in monomeric form To Be Published 0 0 0 0 6JXG 31700541 Crystasl Structure of Beta-glucosidase D2-BGL from Chaetomella Raphigera 2019-04-23 2019-11-20 Kao, M.R.,Kuo, H.W.,Lee, C.C.,Huang, K.Y.,Huang, T.Y.,Li, C.W.,Chen, C.W.,Wang, A.H.J.,Yu, S.M.,Ho, T.H.D. Chaetomella raphigerabeta-glucosidase D2-BGL has intriguing structural features and a high substrate affinity that renders it an efficient cellulase supplement for lignocellulosic biomass hydrolysis. Biotechnol Biofuels 2019 12 258 258 6JU0 31907057 Mouse antibody 3.3 Fab in complex with PEG 2019-04-12 2020-02-05 Lee, C.C.,Su, Y.C.,Ko, T.P.,Lin, L.L.,Yang, C.Y.,Chang, S.S.,Roffler, S.R.,Wang, A.H. Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci. 2020 27 12 12 7X4O 35506766 Crystal structure of Vps17p PX from S. cerevisiae (Space) 2022-03-03 2022-05-18 Obita, T.,Inaka, K.,Kohda, D.,Maita, N. Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae. Acta Crystallogr.,Sect.F 2022 78 210 216 7X4V Crystal structure of Rhodostomin ARGDDP mutant 2022-03-03 2023-03-08 Chang, Y.T.,Chuang, W.J. Crystal structure of Rhodostomin ARGDDP mutant To be published 0 0 0 0